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Future of health = the home 13 SEPTEMBER 2018 Zayna Khayat, Ph.D. Future Strategist, SE Health Adjunct Faculty, Rotman School, U of T Faculty, Singularity University @ZaynaKhayat #SEFutures @SEHealth_SEHC Photo by Luke Stackpoole on Unsplash

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Future of

health =

the home

1 3 S E P T E M B E R 2 0 1 8

Zayna Khayat, Ph.D.Future Strategist, SE Health

Adjunct Faculty, Rotman School, U of T

Faculty, Singularity University

@ZaynaKhayat #SEFutures @SEHealth_SEHC

Photo by Luke Stackpoole on Unsplash

Central paradigm: The system

New paradigm: The Person

Future of Health

@ZaynaKhayat

Central paradigm: The system

New paradigm: The Person

Future of Health

$

@ZaynaKhayat

“Our government is committed

to building 15,000 new long-

term care beds in the next five

years and 30,000 in 10 years.”

– Ontario MP, August 2018

Central paradigm: The system

New paradigm: The Person

Future of Health

$

@ZaynaKhayat

500 BC-500 AD

Hippocrates

500-1500

Black

Plague

1670

Microscopy

of cells

1796

Smallpox

vaccination

1799

Anaesthesia

1870s

Microbes

& disease

1628

Human

Anatomy &

Physiology

1895

X rays

1928

Antibiotics

1948

WHO

established

by UN

1953

DNA structure

Watson & Crick

1971

Medical

Imaging -

MRI, CAT

1978

1st "test tube

baby“

1983

HIV virus

causes

AIDS

2008

Digitiza-

tion

2003

Human

Genome

Source: Adapted from PWC Health @ZaynaKhayat

Future: Person

Proactive, preventative, predictive

Personalized, intelligent

Digi-cal | decentralized

Continuous | team

People-powered

Value, outcomes

Reactive, sick care

1 size fits all, crude, analog

Institution-centred

Episodic, intermittent, silo’d

Provider

Volume, inputs, costs

Today: System

TIMING

PRECISION

MODALITY

DURATION

POWER

CURRENCY

Future of Health

Where

health

is

created

Drivers

of health

Where we

invest

Source: NEHI Analytics (2013)

Medical Care 90%

Behaviour 9%

Other 1%

Access to care 9%

DNA Code20%

Postal Code 22%

Behaviour37%

Interactions of above - 15%

@ZaynaKhayat

(currently, but not for long …)

NEJM Catalyst - Do Hospitals Still Make Sense? The Case for Decentralization of Health Care Article · December 20, 2017Deep Dive - The healthcare of tomorrow will move away from hospitals – April 2017

@ZaynaKhayat

A hospital

designed to

keep people

out of

hospital

“If you have to go to the hospital, we

have failed you.” CEO, Aetna

From hospital → health village

Farmer’s markets - target neighborhoods

Housing|Transportation|Employment

Primary care “Plus” – SDOH + 1 care

$200M Impact Fund – housing stability

Voice as

biomarker

= the “new

vital sign”

2000 – Portals

2010 – Mobile apps

2020 – Voice, conversation

Source of image: Precision Public Health Summit

Public healthAI & Predictalytics

Traditional medicine

Digital biomarkers: predictalytics

@ZaynaKhayat

“Medicine has been a clinical science supported by data.

…becoming a data science supported by clinicians”

Dr. Brad Perkins, Chief Medical Officer, Human Longevity Inc.

Socionome

Phenome =

Traditional

medical record

Panome

https://www.ted.com/talks/daniel_kraft_the_pharmacy_of_the_future_personalized_pills_3d_printed_at_home?utm_campaign=tedspread&utm_medium=referral&utm_source=tedcomshare#t-87478

Fast Company@ZaynaKhayat

Future: Person

Proactive, preventative, predictive

Personalized, intelligent

Digi-cal | decentralized

Continuous | team

People-powered

Value, outcomes

Reactive, sick care

1 size fits all, crude, analog

Institution-centred

Episodic, intermittent, silo’d

Provider

Volume, inputs, costs

Today: System

TIMING

PRECISION

MODALITY

DURATION

POWER

CURRENCY

Future of Health

People Paper & PensBricks

De-centralized

De-physicalized

De-materialized

De-monetized

Dis-intermediated

Digi-calFax Machines

@ZaynaKhayat

22

VR = digital therapeutic (better than some drugs!)

@ZaynaKhayat

Threshold changes in affordability ~$1000

Wearable / portable MRI

Non-invasive

wearable

replaces

cochlear

implants

Personal robots to

support

ADL

Digital

divide?

• Changing paradigm of time, space, distance

• New venues and modalities to access care

SensorsVoice

Healthcare goes Omni-channel

phone

@ZaynaKhayat

Unbundling of the hospital

“70% of what is

currently done

at the hospital,

will not be

done at the

hospital”

“mobile first;

physical next”

New Dutch health ministry (October 2017)

• 2 billion € removed from “cure” budget [hospitals]

• 1.5 billion € added to elderly “care” budget [community, home, primary care]

“Healthcare with no address”

• 18 hospitals

• 2 campus university

• Think and work like a startup

• Partnerships with VCs, tech

giants & startups

• Example – post-surgery rounds

w/ patient at home

“no new

inpatient

beds”

Hospitals

without

beds

... Hospitals evolve into outpatient wellness centers

where the building’s physical structure is a single entity

of service points”

33

Primary care in your pocket

This is a hologram

1st AI

enabled

chatbot for

caregivers

Digital companions

@ZaynaKhayatSource: Lucien Engeln

Care robots

in the home

https://www.facebook.com/techinasia/videos/1438092306229178/

“Mini-bar” in the home?

(re-stocked by drones)

Micro clinics in the

neighbourhood?

https://flipboard.com/@zaynak/biz-model-innovation-in-health(care)-4ak3unq7y/china%E2%80%99s-newest-fad%3A-workout-pods-in-the-middle-of-the-

street/a-W_bQpn4DQ4mVMZKQo6_Lqw%3Aa%3A2045816252-6ca222b37e%2Ftechinasia.com; http://carterjensen.com/2018/02/01/forget-online-shopping-

walmart-patents-a-store-built-right-in-your-home/

@ZaynaKhayat

“people

live in their

homes;

doctors

live at the

clinical

sites”

World’s 1st Virtual Decentralized Clinical Trial Platform

Traditional Model(hospital sites)

Meta Site Model

Source: Noah Craft, MD, PhD, CEO & Founder, Science 37 (Exponential Medicine November 2018)

Future: Person

Proactive, preventative, predictive

Personalized, intelligent

Digi-cal | decentralized

Continuous | team

People-powered

Value, outcomes

Reactive, sick care

1 size fits all, crude, analog

Institution-centred

Episodic, intermittent, silo’d

Provider

Volume, inputs, costs

Today: System

TIMING

PRECISION

MODALITY

DURATION

POWER

CURRENCY

Future of Health

Nesta; NEJM Catalyst – Rhoades DR, McFarland KF, Finch WH, Johnson AO. Family Medicine 33(7): 528-32 (2001); Image from Augmented Health(care) by Lucien Engelen (2018)

Hours living

with chronic

illness

(5,800 hrs /

year)

Hours

accessing

formal

care

@ZaynaKhayat

Formal & informal

caregivers remote

access to vital signs

from anywhere

Patch cardiac rhythm

monitor continuously

for weeks

Bed sensors:

presence, sleep

pattern, heart

rate, breathing,

Person or home: falls,

wandering, meds, …

Sensors: 24/7 remote monitoring

Continuous noninvasive –

glucose, other biomarkers

Source: adapted from PWC

“Apple Watch is moving from a trendy option to a clinical

imperative”

“intelligent guardian for your health”

Source: The Medical Futurist (https://medicalfuturist.com/the-body-map-of-digital-health-sensors) ; Daniel Kraft, Singularity University Exponential Medicine (2017)

Footables (gait)

Sockables (diabetic foot)

Trainables

Shockables

Shakeables (Parkinsons)

Hearables/ringables

Sleepables

Insideables (drugs, glucose)

Breathables (detect cancer)

Steamables (as biomarker)

Moveables (smog)

Foodables (gluten,nuts,cals)

Drinkables (Proof);

Shirtables (sweat, vitables)

Protectables (stop

from falling)

Pain-ables (treat pain

without drugs)

Menstruables

Peeables

Poopables

“It will be retro to have your

blood pressure taken by a

human again”

Future: Person

Proactive, preventative, predictive

Personalized, intelligent

Digi-cal | decentralized

Continuous | team

People-powered

Value, outcomes

Reactive, sick care

1 size fits all, crude, analog

Institution-centred

Episodic, intermittent, silo’d

Provider

Volume, inputs, costs

Today: System

TIMING

PRECISION

MODALITY

DURATION

POWER

CURRENCY

Future of Health

As was predicted … (in 1995)

Tom Ferguson, “Consumer Health Informatics”, Healthcare Forum Journal, 1995, pp28-33

“Patients are the (untapped)

renewable resource of

healthcare”

- Mark Britnell (KPMG)

“Most exciting innovation of our

era is not access to medical

information, but access to each

other” - Susannah Fox

Dermatology

Anemia

Urinalysis (colorometrix)HIV

Test

Ultrasound

Personal diagnostics

Infection monitoring

Opthalmology

Smart thermometer patch

ECG

Pulse

Ox

Otoscope

Smart scale

X-Ray

“Consumer devices

in our homes will

know more about

us than the clinic”

Gerontechnology

DIY, at-home kits

Prosthetics

Hearing aids

Pills

Orthodontics

Biologics

New forms of mobility

REShape Health Innovation Centre, Radboud university medical center (Netherlands)

Providers

Individuals

“If you can have a social network of 1.4 billion people, why can’t you have a medical network of billions of people?” Dr. Eric Topol

“When you think of medicine, you won’t think of 1 doctor, you’ll think of a global community of experts aggregated to make sure that every patient gets their answer quickly and inexpensively”

Future: Person

Proactive, preventative, predictive

Personalized, intelligent

Digi-cal | decentralized

Continuous | team

People-powered

Value,outcomes,fee-4-health

Reactive, sick care

1 size fits all, crude, analog

Institution-centred

Episodic, intermittent, silo’d

Provider

Volume,costs,fee-4-service

Today: System

Future of Health

TIMING

PRECISION

MODALITY

DURATION

POWER

CURRENCY

@ZaynaKhayat“Fee-for-health” coined by Daniel Kraft, MD, PhD in Augmented Healthcare (2018)

@ZaynaKhayat

“Soon it will cost

less to sequence a

genome than to

flush a toilet”

Ray McAuley, Singularity University

@ZaynaKhayat

@ZaynaKhayat

PPATH

24/7 Phone line Virtual Rounds

Integrated Care

CoordinatorsVirtual Care &

Telemonitoring

Integrated

Patient Record

Follow-up clinic

Putting Patients at the Heart Cardiac Surgery Bundled Care Success

2 DaysLength of Stay

38%Readmission Rate

230%Patients Receiving

Community Supports

13%Overall Costs

7

Bundled payments: hospital-to-home

@ZaynaKhayat

http://film.karolinska.se/media/KLEJ5MjiWgIvHtYOLLejPQ/karolinskas-new-operating-model-and-value-based-health-care

Re-base

operating

model and

business

model

By 2022:

50% disease burden

funded based on

outcome indicators

•Autonomous ride hailing service

•Seniors communities

•Chrysler Pacifica – fits wheelchair

Strategy: creative financing vehicles

$22 million PE fund investing in building blocks

of healthy communities in Massachusetts

Disease

prevention

initiatives

impacting >370k

residents in MA

$200M

Co-op bank + Kresge Foundation + Morgan Stanley

Focus on housing

Wellness Trusts

$200M Impact Fund – housing stability

New financing vehicles

@ZaynaKhayat

• 2006: 1 team of 4 nurses

• 2017: 850 teams (10,000

nurses) … with no

recruitment

• Independent, autonomous

front-line teams of nurses

• No management … only

coaches

• Lower cost, higher quality,

happier staff

• Scale: national, USA, Japan,

Korea, Sweden, Germany +

15 other countries

Tuesday 9 May 2017 - The Guardian

New org

models

Future: PersonToday: System

Future of Health = Innovation

Proactive, preventative, predictive

Personalized, intelligent

Digi-cal | decentralized

Continuous | team

People-powered

Value,outcomes,fee-4-health

Reactive, sick care

1 size fits all, crude, analog

Institution-centred

Episodic, intermittent, silo’d

Provider

Volume,costs,fee-4-service

TIMING

PRECISION

MODALITY

DURATION

POWER

CURRENCY

@ZaynaKhayat

66

@ZaynaKhayat

Vala Afshar; Citi Digital Strategy Team; Michael Felton, The New York Times (in HBR.org)

Time to reach 50 M users

17 yrs

Average time

from

evidence to

practice in

medicine: 17

years

@ZaynaKhayat

Source: Accenture Research Disruptability Index– in HBR.org, How Likely Is Your Industry to Be Disrupted? (Jan 2018)

Susceptibility to future disruption

Current disruption

Healthcare delivery

New Entrants: customer obsessed,

savvy with exponentials, patient

@ZaynaKhayat

@ZaynaKhayat

@ZaynaKhayat

Libraries, restaurants, barbershops,

retailers – mental health care

74

Independent living services

New players delivering home care

“The home setting

and health services

will become so

synonymous that

they may not be

called home care;

rather, they will just

be modern health

care”Home Care Could be Heart of the U.S. Health System by 2024, Leaders Say (2015)

KEEP CALM & KEEP INNOVATING

Zayna Khayat, Ph.D.

SE Futures

[email protected]

@ZaynaKhayat |@SEFutures |@SEHealth_SEHC

Image source: Samsung