gastrointestinal dysfunction in children.pptx

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    GASTROINTESTINAL DYSFUNCTION

    IN CHILDREN

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    FAILURE TO THRIVE

    Deceleration fromestablished growthpattern or consistently

    below the 5thpercentile for heightand weight on standardgrowth charts;

    sometimesaccompanied bydevelopmental delays

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    Spitting up or regurgitation

    Passive transfer of gastric contents into the

    esophagus or mouth

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    Vomiting

    Forceful ejection of gastric contents; involves

    a complex process under central nervous

    system control that causes salivation, pallor,

    sweating, and tachycardia; usually

    accompanied by nausea

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    Projectile vomiting

    Vomiting accompanied by vigorous peristaltic

    waves and typically associated with pyloric

    stenosis or pylorospasm

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    Nausea

    Unpleasant

    sensation vaguely

    referred to the

    throat or abdomen

    with an inclination

    to vomit

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    Constipation Passage of firm or

    hard stools orinfrequent passageof stool withassociated

    symptoms such asdifficulty expellingthe stools, bloodstreaked stools,and abdominal

    discomfort

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    Encopresis

    Overflow of incontinent stool causing soiling;

    often caused by fecal retention or impaction

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    Diarrhea

    Increase in the numberof stools with increasedwater content as aresult of alterations ofwater and electrolytetransport by thegastrointestinal(GI)tract; may be acute orchronic

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    Hypoactive, hyperactive, or absent

    bowel sounds

    Evidence of intestinal motility problems that

    may be caused by inflammation or obstruction

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    Abdominal distension

    Protuberant contour of the abdomen that may

    be caused by delayed gastric emptying,

    accumulation of gas or stool, inflammation, or

    obstruction

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    Abdominal pain

    Pain associated with the abdomen that may

    be localized or diffuse, acute or chronic; often

    caused by inflammation, obstruction or

    haemorrhage

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    Gastrointestinal bleeding

    Bleeding from an upper or lower GI source;

    may be acute or chronic

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    Hematemesis

    Vomiting of bright red blood or denatured

    blood that results from bleeding in the upper

    GI tract or from swallowed blood from the

    nose or oropharynx

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    Melena

    Passage of dark-colored, tarry stools caused

    by denatured blood, suggesting upper GI tract

    bleeding or bleeding from the right colon

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    Hematochezia

    Passage of bright red blood per rectum,

    usually indicating lower GI tract bleeding

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    Jaundice

    Yellow coloration of the skin and sclerae

    associated with liver dysfunction

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    Dysphagia

    Difficulty swallowing caused by abnormalities

    in the neuromuscular function of the pharynx

    or upper esophageal sphincter or by disorders

    of the esophagus

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    Dysfunctional swallowing

    Impaired swallowing resulting from central

    nervous system defects or structural defects of

    the oral cavity, pharynx or esophagus; can

    cause feeding problems or aspiration

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    Fever

    Common manifestations of illness in children

    with GI disorders; usually associated with

    dehydration, infection or inflammation

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    GASTROINTESTINAL DIAGNOSTIC

    PROCEDURES

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    Stool examination

    Gross, microscopic,

    and chemical

    examination of stool

    specimen

    to detect normal and

    abnormal

    constituents

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    Ova and parasites (O&P)

    Microscopic examination of stool contents for

    parasites of their eggs

    To aid in diagnosis of parasitic infection

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    Bacterial Culture

    Sample contents grown on culture medium

    Detect bacterial pathogens in stool

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    Stool assay for viral pathogens

    ELISA(enzyme-linked immunosorbent assay)

    Detect viral pathogens in stool

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    Quantitative fat

    Detection of abnormal quantities of fat in

    stool

    Diagnosis of pancreatic insufficiency or

    malabsorption by measuring stool-reducing

    substances

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    Reducing substances

    unabsorbed sugars measured in stool

    To detect elevated levels of reducing

    substances in stool, which are abnormal and

    suggest carbohydrate malabsorption

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    pH

    Stool pH

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    Occult blood guaiac test

    Stool smeared on guaiac-impregnated paper,

    and 2 drops of developing solution added to

    reverse side; blue color indicates hemoglobin

    detect presence of blood in stool

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    Serology test

    Blood test for antibody to H.pylori

    assess for exposure to H. pylori

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    Urea breath test

    Collection of breath after ingestion of isotopic

    urea with either carbon 14 or carbon 13;

    measures labelled carbon dioxide in expired

    air

    Determine if there is active infection with

    H.pylori in the stomach

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    Urease test

    Biopsy of stomach, which is stained and

    placed in Christensen urea medium which

    turns color in presence of H.pylori

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    Pancreatic function

    pancreatic secretions collected via duodenal

    tube under stimulated conditions and

    analyzed for water, ions and enzymes

    determine functional secretory capacity of

    pancreas

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    D-Xylose absorption test

    D-xylose solution administered orally; serum

    levels of D-xylose measured at 30, 60, 90, and120 min

    urine collected for total of 5 hr. to measure D-xylose excretion

    Evaluate absorptive capacity of small intestinalmucosa

    diagnose small-bowel malabsorption caused

    by celiac disease

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    Hepatobiliary scintigraphy

    Nuclear medicine study

    Radiopharmaceutical administered

    intravenously, then sequential images of liver,

    biliary system, and bowel obtained

    evaluate conditions of liver and biliary tract

    abnormalities and gallbladder disease

    diagnosis and monitoring of these conditions,

    such as biliary atresia

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    Breath hydrogen test

    non-invasive study to asses for carbohydrateintolerance

    Hydrogen is generated in colon by bacterialfermentation of undigested carbohydrates and is

    then absorbed into blood, where it diffuses intoexpired air via lungs

    evaluate bacterial overgrowth, lactase or sucrase-isomaltase deficiency

    evaluate malabsorption or bacterial overgrowthby detecting rise in expired hydrogen after oralloading with specific carbohydrate

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    Esophageal pH monitoring

    probe that measures pH placed through nose

    into distal esophagus and records pH over

    time

    determine frequency and duration of gastric

    acid reflux into the esophagus

    establish association between patient

    symptoms(pain, apnea, failure to thrive,

    asthma, wheezing) and acid reflux

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    Upper GI, colonoscopy; flexible

    sigmoidoscopy, anoscopy

    Endoscope introduced into area to be

    examined

    Endoscope has flexible-tip light source and

    aspiration and instrument channel

    directly visualize GI tract to evaluate

    abnormalities, detect lesions, obtain biopsies

    perform therapeutic procedures

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    Ultrasonography

    To locate, measure and delineate abdominal

    organs

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    Computed tomography (CT)

    to visualize horizontal and vertical cross

    section of abdomen at any axis

    To distinguish density of various tissue

    structure or organs

    To detect blunt trauma to internal organs and

    masses

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    ( )

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    Magnetic resonance imaging (MRI)

    to visualize internal body structures in any

    plane; permits soft tissue discrimination

    unavailable with many technique