gene snp 2010
TRANSCRIPT
FDA Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
The Basics - Genes
• Segments of DNA that encode instructions to our cells
• Nucleotides link the two strands of our DNA
• These bases are the alphabet of our genetic code
The Basics - SNPs
• Single nucleotide polymorphism• Result of cell division • Occur in at least 1% of
the population
Understanding the Impact
A T
C G
G T
A T
C G
A T SNP
Gene sends message to encode protein
Protein is created based on message from gene
Parent Child
Areas of Health
• Detoxification• Inflammation• Heart Health• Alcohol Metabolism• Bone Health• Insulin Resistance• Fitness/Weight Management
Detoxification
Gene Impact
CYP1A1 Genotoxic intermediates
CYP1A2 Genotoxic intermediates
GSTM1 Phase II detoxification
GSTP1 Enzyme activity
MnSOD Mitochondrial antioxidant protection
CuZnSOD/SOD3 Antioxidant protection
Inflammation
Gene Impact
CBS Homocysteine
GSTT1 Oxygen radicals
IL-6 Immune cells
TNF-alpha Immune cells
Heart HealthGene ImpactACE Blood pressure and triglyceridesAGT Blood pressure
APOC3 Cholesterol and triglycerides
CETP Cholesterol and triglyceridesLIPC Hepatic lipaseLPL LDL and blood pressure
MTHFR Homocysteine
MTR HomocysteineMTRR General
ENOS/NOS3 Nitric oxide production
PON1 LDL oxidation
Alcohol Metabolism
Gene Impact
ADH1B Conversion of alcohol to acetaldehyde
ADH1C Conversion of alcohol to acetaldehyde
ALDH2 Activity of aldehyde dehydrogenase 2
Insulin Sensitivity
Gene Impact
ACE Insulin sensitivity
CRP Insulin sensitivity
LIPC Glucose disposal and oxidation
PPARY2 Insulin sensitivity
PPARGC1A Insulin sensitivity
VDR Fasting glucose and insulin sensitivity
Fitness and Weight Management
Gene Impact
ACE Muscle mass, use and retention
ADRB2 VO2 Max
CRP VO2 Max
IL-6 Muscle recovery
ENOS Nitric oxide production
PPARGC1A VO2 Max
TNF-Alpha Muscle recovery
Gene SNP™ and Transitions™
• Gene SNP dietary recommendations linked to Transitions Lifestyle System®
• Dietary needs based on your genes linked to low GI solutions
Gene SNP™ Dietary Recommendations
• Eating for optimal heart health– Dietary fat intake– B vitamins
• Eating for optimal bone health– Caffeine– Vitamin D and calcium
• Preventing nutrient deficiencies– Antioxidants– Vitamins and minerals
Gene SNP™ and Supplements
• Isotonix OPC-3®• Advanced Level 90 ®• Isotonix® Isochrome• Heart Health™
Advanced Lipitrim Ultra• Isotonix Calcium Plus• Curcumin Extreme• Isotonix Vision
• Isotonix Resveratrol• Isotonix Advanced B-
Complex• Heart Health Essential
Omega III• Isotonix Multivitamin• Isotonix Vitamin D with
K2
What Gene SNP™ Offers
• Secure online customer profile which can be updated at any time
• Affordable and comprehensive kit evaluates SNPs associated with numerous aspects of health
• Comprehensive online health action plan that offers solutions related to diet, exercise, lifestyle changes and supplementation
• Provides ongoing personal support from a customer manager
• BV!!
Getting Started
Purchase your Gene SNP Kit
Obtain DNA sample from cheek swab and mail swab and consent forms to lab
Complete your secure online customer profile
When your results are ready, view your complete Gene SNP Health Action Plan online
Get results! Achieve optimal health by following recommendations based on your genetic profile. Continuously update your customer profile to monitor your progress!