genetically modified organs

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This is a powerpoint presentation that briefly explains the problem and solutions of genetically modified organisms.

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    Genetically ModifiedOrganisms

    Conie Angulo

    Ali M. MeghadadiWriting 39C/ 33374

    June 4, 2014

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    Problem

    Lack of Organs

    122,439 people that need an organsOnly 14,000 donors

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    Genetically Constructed

    Organs(Anthony Atala, Wake Forrest Baptist medical center)

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    History Genetic Code

    Stem Cell Research Tissue Engineering

    Genetically

    Constructed Organs

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    Tissue Engineering

    1. Obtain the

    Cells2. Grow them

    outside of the

    body

    3. Print the

    scaffold

    4. Scaffolds =

    printed organBerger

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    Problems

    Early Works

    Scientist estimate clinical trials in 10 to 15

    years

    More money and time is being spent

    Technological barriers (unviable organs)

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    Xenotransplantations

    Practice oftransplanting,

    infusing living

    cells, tissues or

    organs from one

    species to another

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    Successes

    Transplanted cells have been used fordiabetes, Alzheimers and Parkinson's

    disease

    Helped show improvement in life threating

    diseases

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    Controversy

    Moral and ethical

    Views

    Health Risks

    Rejection Rates

    Animal Activist

    Protesters outside a lab in San Diego, 2002 (Berger)

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    Future of medicine

    Selective breeding

    Immunosuppressant

    and containment

    Pigs are slaughtered

    everyday Only possible

    solution to the lack

    of organs

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    Works Cited

    "Animal Organs in Humans: Unresolved Risks." U.S National Library of Medicine. U.S. National

    Library of Medicine, 28 Oct. 2013. Web. 19 May 2014.

    .

    Atala Anthony: Printing a Human kidney Perf. Atul Gawande. TED Talk, 2011. Video.

    Brunt, Keith R., Richard D. Weisel, and Li Ren-Ke. "Stem Cells And Regenerative Medicine --

    Future Perspectives." Canadian Journal Of Physiology & Pharmacology90.3 (2012): 327-335.Academic Search Complete. Web. 1 May 2014.

    "Diaries of Despair Protest ."Xenotransplantation (Animal to Human Transplants). Uncaged, n.d.

    Web. 27 May 2014. .

    Hani, Homayoun, et al. "Caprine Pncreatic Islet Xenotransplantation Into Diabetic

    Immunosuppressed BALB/C Mice."Xenotransplantation21.2 (2014): 174-182.Academic Search

    Complete. Web. 13 May 2014.

    Heneine, W. (n.d.). [Web Based Recording]. How big is the risk? Organ farm Retrieved fromhttp://www.pbs.org/wgbh/pages/frontline/shows/organfarm/interviews/heneine.html

    Piguet P, Poindron P (eds): Genetically Modified Organisms and Genetic Engineering in Research

    and Therapy. BioValley Monogr. Basel, Karger, 2012, vol 3, pp 132

    "Uniting People and Information to Help Save Lives." OPTN: Organ Procurement and

    Transplantation Network. Health Resources and Services Administration, U.S. Department of

    Health & Human Services, 1 May 2014. Web. 1 May 2014. http://optn.transplant.hrsa.gov.

    Xenotransplantation Technology.Revivicor's Technology - Xenotransplantation Technology.Revivicor Incorporation, n.d. Web. 19 May 2014. .

    http://optn.transplant.hrsa.gov/http://optn.transplant.hrsa.gov/http://optn.transplant.hrsa.gov/http://optn.transplant.hrsa.gov/