genetics - wordpress.com · genetics was founded with the work of ... ex. blood type, roan horses...
TRANSCRIPT
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Chapter 9 Genetics
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MENDEL’S LEGACYSection 1
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Genetics is the field of biology devoted to understanding how characteristics are transmitted from parents to offspring
Genetics was founded with the work of Gregor Johann Mendel, an Austrian monk who experimented with garden peas
This section describes Mendel’s experiments and the principles of genetics that resulted from them
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Gregor Mendel Knowledge of
statistics valuable to his research on heredity handing down of characteristics from parent to offspring
Did experiments on garden pea, Pisum sativum
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Mendel’s Garden Peas Observed 7 characteristics◦ Each occurred in two contrasting traits
Plant height (long/short stems) Flower position (side/top) Pod color (green/yellow) Pod appearance (big/small) Seed texture (smooth/wrinkled) Seed color (yellow/green) Flower color (purple/white)
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Self-Pollination
Pollen transferred from the anthers of a flower to stigma of either the same flower or a flower on the same plant
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Cross-Pollination
Pollen transferred from anthers of a flower to stigma of a flower on a different plant
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Mendel’s Experiments Studied each characteristic and its
contrasting traits individually Began with true-breeding plants
always produce offspring with same trait
Strain plants that are pure for a specific trait
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Produced strains by allowing plants to self-pollinate for several generations
Eventually got 14 strains, one for each of contrasting traits
Each strain was called parental generation, or P1 generation
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Then he cross-pollinated two plants, one for each contrasting trait
Resulting offspring were first filial generation, F1 generation
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Mendel took 2 F1 offspring and self-pollinated them◦ Second filial generation, F2
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Mendel’s Results F1 generation ratio
of 4:0 for contrasting traits
F2 generation ratio of 3:1 for contrasting traits
Hypothesis: each trait inherited by controlling factor◦ Must be pair of
factors for each trait
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Mendel’s Conclusion Whenever he crossed P1 strains, one trait
was NEVER in F1 generation That trait would come back in 25% (1/4) of
F2 generation
Hypothesized trait appearing in F1 was controlled by dominant factor because it masked (dominated) the other
Trait that did NOT appear in F1 was recessive
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Dominant factor represented by capital letter◦ Yellow seed = Y
Recessive factor represented by lower case letter◦ Green seed = y
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Law of Segregation One of two laws that come from
Mendel’s experiments
A pair of factors is segregated, or separated, during the formation of gametes (meiosis)
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Law of Independent Assortment
2nd law that comes from his experiments Mendel crossed plants that differed in
TWO characteristics Traits produced by dominant factors
don’t always appear together◦ Green pod on white flowering plant
Factors for different characteristics are distributed to gametes independently
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Chromosomes and Genes Molecular genetics study of structure
and function of chromosomes and genes Remember a gene is a segment of DNA on a
chromosome that controls a trait◦ Chromosomes occur in pairs, so genes occur in
pairs
Each of several alternative forms of a gene allele◦ Mendel’s “factors” alleles
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Alleles Since each trait has alternative forms
(alleles), letters are used to represent dominance and recessiveness
Ex. Yellow seeds may be YY or Yy, since the Y will mask, or dominate, the y
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GENETIC CROSSESSection 2
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Genetic Crosses
Genotype genetic makeup of an organism (Yy)
Phenotype the physical appearance of an organism (yellow seed)
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When both alleles of a pair are alike, the organism is homozygous for that characteristic◦ YY or yy
When alleles are different, the organism is heterozygous for that characteristic◦ Yy
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Probability Likelihood that a specific event will
occur◦ Can be decimal, percentage, fraction
Probability = number of times an event is expect to happennumber of opportunities for an even to happen
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Ex. Dominant trait of yellow seed color appeared in F2 generation 6,022 times
Recessive trait of green seed appeared 2,001 times
6,022 + 2,001 = 8,023 total individuals
6,022/8,023 = 0.75 (75% dominant) 2,001/8,023 = 0.25 (25% recessive)
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Predicting Results Cross between individuals that
involves only 1 set of contrasting traits monohybrid cross
Use Punnett square to predict results of monohybrid cross
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Genotypic Ratios Creating a ratio to
express probability of GENOTYPES
Write possible genotypes◦ TT, Tt, tt
Ratio reflects probability◦ TT:Tt:tt = 1:2:1
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Phenotypic Ratios
Ratio of phenotypes
T = tall, t = short
Ratio of tall:short ◦ 3:1
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Testcross
How do you tell if a yellow seed is YY or Yy?◦ Use testcross
Cross with homozygous recessive
Y Y
y Yy Yy
y Yy Yy
Y y
y Yy yy
y Yy yy
If 100% offspring are yellow, then genotype of
parent is homozygous dominant.
If offspring are 50/50, then genotype of parent is
heterozygous.
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Incomplete Dominance
• Compete dominance dominant allele complete masks recessive allele
• Incomplete dominance alleles mix/blend
• Ex. Four o’clock flowers
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Codominance
BOTH alleles expressed in heterozygous offspring
Neither allele dominant or recessive
Ex. Blood type, roan horses◦ RR’ to show different
alleles
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Dihybrid Crosses
Cross between individuals that involves TWO pairs of contrasting traits
More complicated, more possible combinations
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TTBB = 1/16TTBb = 2/16TtBB = 2/16Ttbb = 2/16TtBb = 4/16TTbb = 1/16ttBB = 1/16ttBb = 2/16ttbb = 1/16
TtBb x TtBb
9/163/163/161/16