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State of the Division 2017 Bruce E. Sands, MD, MS Chief of the Dr. Henry D. Janowitz Division of Gastroenterology Dr. Burrill B. Crohn Professor of Medicine Icahn School of Medicine at Mount Sinai Mount Sinai Health System

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Page 1: GI Division Achievements 2016-2017icahn.mssm.edu/files/ISMMS/Assets/Departments/Medicine/GI Divisi… · Mission% • To#promote#the#health#and#quality#of#life#of# people#with#gastrointes6nal#disorders#by##

State  of  the  Division  2017  

Bruce  E.  Sands,  MD,  MS  Chief  of  the  Dr.  Henry  D.  Janowitz  Division  

of  Gastroenterology  

Dr.  Burrill  B.  Crohn  Professor  of  Medicine  

Icahn  School  of  Medicine  at  Mount  Sinai  

Mount  Sinai  Health  System  

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Mission  

•  To  promote  the  health  and  quality  of  life  of  people  with  gastrointes6nal  disorders  by    

– providing  the  most  innova6ve  and  highest  quality  gastroenterology  care  

– leading  advances  in  the  science  of  gastroenterology  

– training  the  next  genera6on  of  academic  gastroenterologists    

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Appointments  

•  Robert  Hirten,  MD  

•  Pascale  White,  MD  

•  Serre-­‐Yu  Wong,  MD,  PhD  

•  Laura  Frado,  MD  (Voluntary)  

 

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Promo?ons  

•  Laurie  Keefer,  PhD:  Associate  Professor  of  Medicine  and  Psychiatry  

•  SaOsh  Nagula,  MD:  Associate  Professor  of  Medicine  

•  Thomas  Ullman,  MD:  Professor  of  Medicine  

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Michael  Smith,  MD,  MBA  

•  Chief  of  Gastroenterology  and  Hepatology,  MSSL  and  MSW  

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BreA  Bernstein,  MD  

•  Chief  of  Gastroenterology  and  Hepatology,  Mount  Sinai  Downtown  

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Awards  and  Dis?nc?ons  

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Awards  and  Dis?nc?ons  

•  Aimee  Lucas  –  Emerging  Star  Award,  NaOonal  Pancreas  FoundaOon,  2017  

–  ASGE  Leadership  EducaOon  and  Development  (LEAD)  Program,  2017  

•  Julia  AYenborough,  NP  –  Compassionate  Care  Award,  NaOonal  Pancreas  FoundaOon,  2017  

•  Steven  Itzkowitz  –  Chosen  by  ISMMS  Class  of  2017  to  serve  as  Marshal  at  Commencement  

•  Ashish  Atreja  –  IT  InnovaOon  Award  for  RxUniverse,  an  app  prescribing  pla]orm  

–  Nominated  for  Top  40  Healthcare  Transformers  of  2017  

 

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Awards  and  Dis?nc?ons  

•  Michelle  Kim  –  Women’s  ExecuOve  Leadership  Program,  Impact  Center    

•  Ryan  Ungaro  –  Poster  of  DisOncOon,  CCFA  Advances  in  IBD  Conference    

•  Kamron  Pourmand  –  Harvard-­‐Macy  Scholarship  –  InsOtute  of  Medical  EducaOon,  Mount  Sinai  –  ACG  EducaOon  Universe  Editorial  Board  

•  Ari  Grinspan  –  Mount  Sinai  World  Trade  Center  Health  Program  Clinical  Center  AppreciaOon  

Award  

 

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Awards  and  Dis?nc?ons  

•  Chris  DiMaio  –  Editorial  Board,  Video  Gastrointes6nal  Endoscopy  (also  “reviewer  of  the  

month”  award  twice)  –  Selected  to  parOcipate  in  Mount  Sinai  LEAD  (Leaders  Emerging  in  Academic  

Departments)  course  –  Advanced  endoscopist  by  appointment  to  the  Royal  Family  of  Saudi  Arabia    

•  Barry  Jaffin  and  Anthony  Weiss  –  Humanitarian  of  the  Year,  CCFA  New  York  Chapter    

•  Bruce  Sands  –  Henry  D.  Janowitz,  MD,  LifeOme  Achievement  Award,  CCFA,  2016  

 

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Roles  in  Regional,  Na?onal,  and  Interna?onal  Organiza?ons  •  Jerome  Waye,  MD  

–  Chair  of  “Program  for  Endoscopy  Teachers,”  World  Endoscopy  OrganizaOon  

–  Chair  of  the  CommiYee  on  Centers  of  Excellence,  World  Endoscopy  OrganizaOon  

•  Chris  DiMaio,  MD  

–  AGA  Community  Forum  Clinical  Expert  Moderator  for  PancreaOc  Disorders  and  Imaging  and  Advanced  Technology  

–  Member,  ASGE  Research  CommiYee  

•  Steven  Itzkowitz  

–  Member,  NaOonal  Colorectal  Cancer  Roundtable  Steering  CommiYee  

–  Co-­‐Chair,  NYC  C5  CoaliOon  Screening  Guidelines  CommiYee  

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Roles  in  Regional,  Na?onal,  Interna?onal  Organiza?ons  •  Ashish  Atreja,  MD  

–  Member,  PCORI  NaOonal  Advisory  Panel  on  CommunicaOon  and  DisseminaOon  Research  

–  American  College  of  Cardiology,  InnovaOon  Advisory  Board  

–  Co-­‐InvesOgator  in  AGA-­‐led  naOonal  FMT  registry  efforts  

–  Chair,  Registry  SubcommiYee,  Center  for  GI  InnovaOon  and  Technology,  American  Gastroenterological  AssociaOon  

•  Bruce  Sands,  MD  –  Chair,  NominaOng  CommiYee  and  Member  of  Board  of  Trustees,  InternaOonal  

OrganizaOon  for  IBD  

•  Michelle  Kim,  MD  –  ScienOfic  Chair,  Korean-­‐American  Medical  AssociaOon  

–  AGA  RepresentaOve  to  ASCO;  GI-­‐ASCO  Program  CommiYee  

–  AGA,  Research  Policy  CommiYee  

 

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Roles  in  Regional,  Na?onal,  Interna?onal  Organiza?ons  •  David  Greenwald,  MD  

–  American  College  of  Gastroenterology,  Board  of  Trustees  

–  American  College  of  Gastroenterology,  Secretary  

–  GIQuIC,  Chairman  of  the  Research  CommiYee  

–  Citywide  Colon  Cancer  Control  CoaliOon  (C5),  Co-­‐Chairman  

–  NaOonal  Colorectal  Cancer  Roundtable,  Steering  CommiYee,  Co-­‐Chairman  of  Public  Outreach  and  Social  Media  Task  Group  

 

•  Ben  Cohen,  MD  –  Chair,  CCFA  Rising  Educators,  Academicians  and  Clinicians  Helping  IBD  (REACH-­‐

IBD)  

–  Member,  AGA  EducaOon  &  Training  CommiYee  

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Roles  in  Regional,  Na?onal,  Interna?onal  Organiza?ons  •  Saurabh  Mehandru,  MD  

–  Gastroenterology  Merit  Review  CommiYee  (GAST),  Veteran’s  AdministraOon  Research  Program  

–  CCFA  Clinical  Grant  Review  CommiYee  

–  College  of  Reviewers,  Canadian  InsOtute  of  Health  Research    

•  Rob  Hirten,  MD  –  Secretary,  New  York  Crohn’s  &  ColiOs  OrganizaOon  –  Member,  ACG  Training  CommiYee  

 

•  Laurie  Keefer,  PhD  –  Chair,  Psychogastroenterology  SecOon,  Rome  FoundaOon  

–  Member,  Ethics  CommiYee,  AGA  

 

 

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Roles  in  Regional,  Na?onal,  Interna?onal  Organiza?ons  •  Christopher  DiMaio,  MD  

–  President,  NYSGE  –  Member,  ASGE  Research  CommiYee  

 •  David  Faleck,  MD  

–  Vice-­‐Chair  of  EducaOon,  Crohn’s  &  ColiOs  FoundaOon  NYC  Fellow’s  CommiYee  

 

•  Kamron  Pourmand,  MD  –  Co-­‐Instructor,  Harvard-­‐Macy  Scholarship  Course,  2017  

 

 

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Editorial  Roles  

•  Bruce  Sands  –  Editorial  Board  for  Inflammatory  Bowel  Diseases  

•  Jean-­‐Frederic  Colombel  –  Associate  Editor  for  Gastroenterology  

•  Ashish  Atreja  –  Associate  Editor  for  Inflammatory  Bowel  Diseases  

•  Chris  DiMaio  –  Editorial  Board,  Video  Gastrointes6nal  Endoscopy  

•  Saurabh  Mehandru  –  Editorial  Board  for  Gastroenterology  

•  Kamron  Pourmand  –  Editorial  Board  for  ACG  Educa6on  Universe  

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Major  Administra?ve  Posi?ons  at  Icahn  School  of  Medicine  at  Mount  Sinai  and  Mount  Sinai  Health  System  •  Tom  Ullman,  MD  

–  Chief  Medical  Officer,  Mount  Sinai  Doctors  Faculty  PracOce  

–  Senior  Associate  Dean  for  Clinical  Affairs  •  Ashish  Atreja,  MD  

–  Chief  Technology  InnovaOon  and  Engagement  Officer,  Department  of  Medicine  

•  Brijen  Shah,  MD  

–  Chief  Medical  Officer,  Mount  Sinai  Queens  

•  Judy  Cho,  MD  

–  Director  of  the  InsOtute  for  Personalized  Medicine  

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Reputa?on,  Impact,  Research  and  Innova?on  

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US  News  &  World  Report:    Overall  Ranks,  2017  

Hospital   Overall  Rank  

Mayo  Clinic   1  

Cleveland  Clinic   2  

Johns  Hopkins   3  

Cedars-­‐Sinai   4  

MGH   5  

UPMC   6  

Mayo  Jacksonville   7  

Mount  Sinai   8  

University  of  Michigan   9  

Mayo  Clinic  Phoenix   10  

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US  News  &  World  Report:    Rank  by  Reputa?on  Scores,  2017  

Hospital   Overall  Rank   Reputa?on  Score   Reputa?on  Rank  

Mayo  Clinic   1   46.5%     1  

Cleveland  Clinic   2   30.3%     2  

Johns  Hopkins   3   23.3%     3  

Cedars  Sinai   4   7.8%%     7  

MGH   5   17.4%     4  

UPMC   6   8.5%     6  

Mount  Sinai   7   11.1%     5  

Mayo  Jacksonville   8   5.6%     9  

University  of  Michigan   9   6.7%     8  

Mayo  Clinic  Phoenix   10   4.6%     10  

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GI  Research  Funding  as  of  July  2017  

TYPE Count Total  Directs Total  Indirects TOTALCLINICAL  TRIALSInflammatory  Bowel  Disease  (IBD) 23 4,008,821$                     1,428,491$                         5,437,312$                    Neuroendocrine  Tumor  (NET) 2 150,597$                           52,709$                                   203,306$                          Biliary 3 -­‐$                                         -­‐$                                               -­‐$                                        Other/General  GI 6 150,608$                           52,713$                                   203,321$                          

TOTAL  CLINICAL  TRIALS 34 4,310,026$                     1,533,913$                         5,843,939$                    GRANTSNational  Institutes  of  Health  (NIH) 10 4,809,647$                     1,750,942$                         6,622,067$                    Foundation 13 4,339,476$                     928,812$                               5,268,288$                    Industry 4 544,648$                           219,819$                               764,466$                          Career  Development  Award 2 289,255$                           -­‐$                                               289,255$                          State/Federal  Government 1 27,984$                               9,515$                                       37,499$                              University   8 706,557$                           330,457$                               1,037,015$                    

TOTAL  GRANTS 38 10,717,567$                 3,239,545$                         14,018,590$                MOUNT  SINAI  FUNDEDTOTAL  MOUNT  SINAI  FUNDED 43 N/A N/A N/A

TOTAL  CURRENT  PROJECTS 115 15,027,593$     4,773,458$               19,862,529$    

Clinical Trial and Grant Funding Snapshot (July 2017)

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Grant  Funding:  2016  vs.  2017  

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Research  Grants  

•  Jean-­‐Frederic  Colombel,  Judy  Cho,  Ari  Grinspan  

–  SUCCESS  2.0  (Sinai  UlceraOve  ColiOs:  Clinical,  Experimental  and  Systems  Studies);  anonymous  donor  

•  Ari  Grinspan  –  George  Waechter  FoundaOon  Grant  

•  Jean-­‐Frederic  Colombel  

–  CCFA:  Personalized  IBD:  the  role  of  microbiome  diversity  in  intesOnal  inflammaOon  (with  Jose  Clemente)  

–  Rainin  FoundaOon:  The  Role  of  Viral  Exposure  Preceding  IBD  Diagnoses  in  Crohn’s  Disease  Pathogenesis  

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Research  Grants  

•  Judy  Cho  –  NIDDK  U01  Renewal  IBD  GeneOcs  Research  ConsorOum  Data  

CoordinaOng  Center  and  GeneOcs  Research  Center  

–  The  Sanford  J.  Grossman  Center  for  IntegraOve  Studies  in  Inflammatory  Bowel  Diseases  at  The  Mount  Sinai  Hospital  

 PROGRESS  

Personalized  Medicine  in  Crohn’s  disease:  Understanding  and  PredicOng  Disease  Progression  towards  Strictures    

 

•  Bruce  Sands  –  OSCCAR  (CDC  U01):  ProspecOve,  populaOon-­‐based  IBD  cohort  in  RI    

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Research  Grants  

•  Janssen/Mount  Sinai  IBD  CollaboraOon  

–  Completed  enrollment,  ongoing  analysis  

–  TransiOon  to  “Road  to  PrevenOon,”  led  by  Marla  Dubinsky,  Jean-­‐Frederic  Colombel  

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Research  Grants  

•  Ashish  Atreja  –  NIH  K23,  “IBDPROMISE:  A  web-­‐based  paOent-­‐centric  model  to  improve  

quality  and  outcomes”  

–  Takeda,  “Real-­‐World  Impact  of  Vedolizumab  on  PaOent-­‐Reported  Outcomes  and  Quality  Indicators:  RetrospecOve  Analysis  of  HealthPROMISE  App  Data”  

•  Aimee  Lucas  

–  American  Cancer  Society  Career  Development  Award,  “EffecOveness  of  PancreaOc  Cancer  Screening  in  High-­‐Risk  Individuals”  

•  Louis  Cohen  –  NIH  K08,  “Defining  Host-­‐Microbial  InteracOons  Using  FuncOonal  

Metagenomics”  

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Research  Grants  

•  Saurabh  Mehandru  

–  NIH  R01,  “Impact  of  HIV-­‐1  infecOon  and  its  treatment  on  gastrointesOnal  B  cells”  

–  Rainin  FoundaOon  Synergy  Award,  “Towards  idenOfying  the  unique  pathology  that  explains  ulceraOve  coliOs  distribuOon”  

–  NIH  R01,  “Mapping  of  neuro-­‐immune  interacOons  in  the  GI  tract,”      (co-­‐I)  

–  NIH  R01,  “Cell  migraOon  and  virologic  synapse  formaOon  in  HIV  transmission,”  (co-­‐I)  

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Research  Grants  

CCFA  Clinical  Research  Consor?um  Pilot  Award  

Steven  Itzkowitz:  SAPPHIRE  Registry    

 Safety  of  Immunosuppression  in  a  ProspecOve  Cohort  of  IBD  PaOents  with  a  History  of  New  or  Recurrent  Cancer  

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Research  Grants  

•  Ryan  Ungaro  –  Mount  Sinai  LK2  Scholars  Award  for  Clinical  and  TranslaOonal  Research  

Career  Development  

–  CCFA  Career  Development  Award  

–  Department  of  Medicine  Junior  Faculty  TranslaOonal  CollaboraOve  Research  IniOaOve  Grant  (co-­‐PI)  

•  Laurie  Keefer  –  Pfizer,  “Understanding  the  impact  of  resilience  on  medicaOon  aqtudes  

and  beliefs  in  UC”  

–  NIAID-­‐DMID-­‐NIH,  “Targeted  clinical  research  to  address  select  viral  infecOons”  

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Publica?ons  

•  152  peer-­‐reviewed  arOcles    •  Wide  coverage  of  content  and  methodology  –  IBD  –  Endoscopy  –  Colorectal  cancer  –  PancreaOc  cancer  –  IBS  –  GI  immunology  –  NETs  –  GeneOcs  –  Clinical  epidemiology  –  Medical  EducaOon  –  GI  Psychology    

 

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Ashish  Atreja:  Mount  Sinai  App  Lab  

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NODE Health is a consortium of health systems to promote evidence based digital medicine.

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Pa?ent  Care  

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GRITT-IBD™ An IBD medical home dedicated to Gaining Resilience

Through Transitions  

Population Health Manager Jonathan Washington, MPH

Psychosocial Care Team Laurie Keefer, PhD

Karen Conlon, LMSW

Nursing Team & Ostomy Care Blossom Hashemi, FNP, Nicole Thomas, FNP

Patricia Lazio, RN, Alexis Sherman, RN

Nutrition Team Laura Manning, RD

Tyffanie Ammeter, RD Joshua Novak, MD

Colorectal Surgeons

Peer Mentoring Nirrit Ganjian, MS

Vetted Peer Mentors

Medical Neighborhood

Pain Program Dermatology OB/GYN, Rheumatology Mount Sinai Adult and

Pediatric Health Homes

Telemedicine Program

Standardized Resilience Screening

Technology Extenders GoLantern

HealthPROMISE

Enrollment Coordinator Gianina Diaz

(212) 824-7724

Child Life Madison Elkow, MS

IBD Patient

Advisory Board

Medical Sociologist Ksenia Gorbenko, PhD

Clinical Pharmacist Stacy Tse, PharmD

Co-Directors Laurie Keefer, PhD and Marla Dubinsky, MD

Gastroenterologists/GI Fellows

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Innova?ons  in  Care  

•  Surgical  endoscopy:  Nikhil  Kumta    •  High  risk  pancreaOc  cancer:  Aimee  Lucas  •  GI  Cancer  and  High-­‐Risk  CRC  Syndromes:  Steven  Itzkowitz  •  InpaOent  BMT:  Steve  Naymagon  •  Deep  Enteroscopy:  Steve  Naymagon  •  BarreY’s  Esophagus:  SaOsh  Nagula  •  Large  Polyps:  Jerry  Waye  (Director  of  Center  for  Advanced  Polypectomy)  •  BMT  for  IBD:  Louis  Cohen  •  Center  for  Carcinoid  and  Neuroendocrine  Tumors:  Michelle  Kim  (Director)  •  NutriOon  Support  Services:  Josh  Novak  (Medical  Director)  •  Fecal  Microbial  Therapies:  Ari  Grinspan  (Director  of  FMT  for  MSHS)  •  GI  Clinic:  Pascale  White  (Director)  •  Early  IBD  Clinic:  Ryan  Ungaro    

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Educa?on  

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Fellowship  Program  

•  Program  Director:  Steven  Itzkowitz  

•  Associate  Program  Director:  SaOsh  Nagula  

•  Chief  Fellows  – Ruby  Greywoode  – Kamron  Pourmand  

 

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Fellowship  Program  

•  Graduated  fellows  –  James  Crismale:  Liver  Transplant,  Mount  Sinai  

–  Joanna  Lopez:  PracOce,  Miami  

–  Shailja  Shah:  Vanderbilt  University  – Eugenia  Shmidt:  University  of  Minnesota  

–  Serre-­‐Yu  Wong:  Mount  Sinai  

 

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Fellowship  Program  

•  New  fellows  – Zachary  Borman:  Beth  Israel-­‐Deaconess  

–  Lauren  Grinspan:  Columbia  University  

– Akash  Kumar:  Mount  Sinai  

–  Sheila  Rustgi:  Mount  Sinai  

 

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Fellowship  Program  

•  Advanced  fellows  –  Sudarshan  Paramasothy  (Present-­‐Levison  Advanced  IBD  Fellow)  

– Zane  Gallinger  (Advanced  IBD  Fellow)  – Zach  Zator  (Wong-­‐Tang  Advanced  Endoscopy  Fellow  in  Honor  of  Dr.  Jerry  Waye)  

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The  Division’s  Fellowship  Teaching  Awards,  2017  

•  Outstanding  Endoscopy  Preceptor  of  the  Year  –  Lawrence  Cohen  

•  Outstanding  OutpaOent  Preceptor  of  the  Year  –  Bruce  Sands  

•  Outstanding  Voluntary  Faculty  of  the  Year  –  Peter  Chang  

•  Outstanding  Teacher  of  the  Year  –  SaOsh  Nagula  

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Mount  Sinai  CME  Programs  

•  Mount  Sinai  Live  Endoscopy  Course  –  1st  Annual  on  March  10,  2017  

–  Course  Directors:  Chris  DiMaio,  David  Greenwald,  Co-­‐Director:  SaOsh  Nagula  

•  Mount  Sinai  Intensive  Review  of  Gastroenterology  and  Hepatology  –  5th  Annual  on  August  10-­‐12,  2017  –  Course  Directors:    Jawad  Ahmad,  Doug  Dieterich,  Ari  Grinspan,  Bruce  Sands,  Tom  

Schiano,  SaOsh  Nagula  

•  Mount  Sinai  Inflammatory  Bowel  Disease  Consultant’s  Course  –  14th  Annual  on  Friday,  October  6,  2017  Goldwurm  Auditorium  

–  Course  Directors:  Jean-­‐Frederic  Colombel,  Marla  Dubinsky,  Asher  Kornbluth,  James  Marion  

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Other  Educa?onal  Programs  

•  James  Marion  

-  Facebook  LIVE:  From  the  Susan  and  Leonard  Feinstein  Clinical  IBD  Center  

-  Pfizer  IBD  TherapeuOc  Drug  Monitoring  Preceptorship  

–  Johnson  &  Johnson  General  OperaOng  CommiYee  Preceptorship  on  IBD  

–  Future  Program:  Takeda  Preceptorship  

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Major  Teaching  Roles  Outside  the  Ins?tu?on  

•  Steven  Itzkowitz  

-  USCAP  (US-­‐Canada  AssociaOon  of  Pathologists)  Annual  MeeOng  Short  Course:  Colorectal  Dysplasia  in  IBD  

-  Course  Co-­‐Director,  AACR  Conference  on  Colorectal  Cancer  •  Louis  Cohen  

-  “Updates  in  ColiOs  for  Hermansky-­‐Pudlak  Syndrome,  “  HPS  Network  Conference,  Uniondale,  NY  

•  Ben  Cohen  

-  IBD  Clinical  PracOce  Video  Series,  Moderator  

•  Saurabh  Mehandru  

–  Plenary  PresentaOon,  InternaOonal  Mucosal  Immunology  Congress,  Toronto,  2016,  “Microbial  modulaOon  of  lung  dendriOc  cell  funcOon”  

–  Invited  Lecture,  InternaOonal  Congress  of  the  Brazilian  Society  of  Mucosal  Immunology,  Salvador,  Brazil  

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Major  Teaching  Roles  Outside  the  Ins?tu?on  

•  Rob  Hirten  

-  Co-­‐Director  and  Organizer,  ACG  2017  Trainee  Luncheon  at  WCOG  

•  Ashish  Atreja  

-  Director,  Digital  Medicine  Conference  2017,  December  4-­‐5,  2017  

-  Invited  Plenary  Talk  on  “Digital  Medicine”  at  AssociaOon  of  Physicians  of  India  (APICON)  

•  Nikhil  Kumta  

-  Director,  NYSGE  David  Falkenstein,  MD  Fellows  Night  

•  Laurie  Keefer  

–  Course  Director,  American  Neurogastroenterology  and  MoOlity  Society  Clinical  Course  

•  Bruce  Sands  

–  4th  Annual  AOlla  Ertan  Lectureship,  University  of  Texas  Health  Science  Center  at  Houston  

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Major  Teaching  Roles  Outside  the  Ins?tu?on  

•  Judy  Cho  -  Organized  “Keystone  Conference,”  “Host  and  the  Environment  in  IBD:  ScienOfic  

Advances  Leading  to  New  TherapeuOcs”  

-  Keynote  Speaker,  Mayo  Clinic  Personalized  Medicine,  “Genomics  of  IBD:  Towards  Precision  Medicine”  

•  Ashish  Atreja  -  Director  of  “Digital  Medicine  2017”    

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