National Consultative WorkshopStrengthening and Road Mapping of Emerging Technology Innovation Systems of Sri Lanka

17-19 November 2015 Colombo, Sri Lanka

Global Emerging Technology Trends : Bio and Nanotechnologies

Mr. N. SrinivasanCoordinator, Science, Technology, and Innovation

Asian and Pacific Centre for Transfer of Technology (APCTT) of theUnited Nations Economic and Social Commission for Asia and the Pacific (UN ESCAP) in New Delhi, India

(Acknowledgement : Assistance in research and preparation of presentation slides byMs. Becky Byler, APCTT Intern, Yale School of Engineering and Applied Sciences, USA)

Presentation OverviewBio and Nanotechnologies

• R&D• Expenditures• Patents• Journal Articles

• Industry• Firms• Sectors• Revenue

• R&D• Expenditures• Patents• Journal Articles*

• Industry• Firms• Sectors• Revenue

Biotechnology

*Data not currently available since definition of “biotechnology” is too broad/inconsistent

Areas:1. Pharmaceuticals2. Healthcare/Diagnostics3. Bioinformatics4. Genetic Engineering5. Genomics/Proteomics6. Animal and Plant

Agriculture/Crop Improvement

7. Food Innovations8. Fermentation Technology9. Energy and Environmental

Management

Most Cited:• DNA coding, mapping, and

sequencing• Protein sequencing, synthesis,

and engineering• Subcellular organism research• Cell and tissue culture and

engineering

Biot

ech

R&D

Expe

nditu

res i

n $U

SD M

illio

ns P

PP

% of Biotech R&D Expenditures of total BERD

Biotech R&D: Private Expenditures (2014)

% of Biotech R&D Expenditures of total public R&D expenses

Biotech R&D: Public Expenditures (2014)

Biot

ech

R&D

Expe

nditu

res i

n $U

SD M

illio

ns P

PP

Biotech R&D: Patents (2006-2011)

Sri Lanka Australia China India Japan Korea Malaysia Thailand Belgium Canada France Germany Spain Switzerland UK USA

Sri Lanka Australia China India Korea Malaysia Thailand Belgium Canada France Spain Switzerland UK

Num

ber o

f Bio

tech

nolo

gy P

aten

ts

Biotech R&D: Global Patent Share (2014)

1.5% Australia4.4% China1.1% India4.9% Korea0.3% Malaysia

0% Thailand

2.4% Canada1.2% Belgium

4.7% France

6.3% Germany

1.6% Spain1.8% Switzerland

3.8% UK

0% Sri Lanka

40.9% USA

11.5% Japan

Biotech R&D: Percent of Total Patents

% o

f Tot

al P

aten

ts

Biotech R&D: Biotech “Advantage” (2014)

THAI

LAN

D: N

O D

ATA

SRI L

ANKA

: NO

DAT

A

Biotech Industry: Number of Firms (2014)

Biotech Industry: Size of Firms (2014)

Japan

Korea

Belgium Canada

France Germany Spain

USAUKSwitzerland

28%

72%

59%

41%

66%

34%51%49%

74%

26% 29%

71% 82%

18%

27%

73%

20%

80%

30%

70%

Small Firms(<50 Employees)

Large Firms(>50 Employees)

Biotech Industry: Revenue (2013-2014)

Biot

ech

Reve

nue

in $

USD

Bill

ions

Biotech Industry: Industrial Sectors (2014)

Biot

echn

olog

y F

irms b

y Ap

plic

ation

Biotech R&D: Research Areas (2014)

Perc

ent o

f All

Biot

echn

olog

y Re

sear

ch A

reas

Nanotechnology

*Data not currently collected

• R&D• Expenditures• Patents• Journal Articles

• Industry• Firms• Sectors*• Revenue

Areas:1. Nanomaterials

(nanoparticles, nanotubes, nanocomposites)

2. Nanotools (nanolithography tools and scanning probe microscopes)

3. Nanodevices (nanosensors and nanoelectronics)

Most Cited:• Graphene• Gold Nanoparticles• DNA nanotechnology• Nanopores• Nanotoxicology

Nanotech R&D: Private Expenditures (2014)

Nan

otec

h R&

D Ex

pend

iture

s in

$USD

Mill

ions

PPP

% of Nanotech R&D Expenditures of total BERD

Nanotech R&D: Public Expenditures (2014)

Nan

otec

h R&

D Ex

pend

iture

s in

$USD

Mill

ions

PPP

% of Nanotech R&D Expenditures of total public R&D expenses

Sri Lanka Australia China India Japan Korea Malaysia Thailand Belgium Canada France Germany Spain Switzerland UK USA

Sri Lanka Australia India Malaysia Thailand Belgium Canada Spain Switzerland

Nanotech R&D: Patents (2006-2011)

Num

ber o

f Nan

otec

hnol

ogy

Pate

nts

Nanotech R&D: Global Patent Share (2014)

0.7% Australia2.6% China1.1% India

8.9% Korea

0.3% Malaysia

0% Thailand

1.4% Canada0.5% Belgium

4.3% France

6.5% Germany

1.9% Spain1.0% Switzerland

3.3% UK

0% Sri Lanka

36.5% USA

18.7% Japan

% o

f Tot

al P

aten

ts

Nanotech R&D: Percent of Total Patents

Nanotech R&D: Nanotech “Advantage” (2014)

THAI

LAN

D: N

O D

ATA

SRI L

ANKA

: NO

DAT

A

Nanotech R&D: Journal Articles (2006-2014)

Sri Lanka Australia China India Japan Korea Malaysia Thailand Belgium Canada France Germany Spain Switzerland UK USA

Sri Lanka Malaysia Thailand Belgium

Num

ber o

f Nan

otec

hnol

ogy

Artic

les

Nanotech Industry: Number of Firms (2014)

Nanotech Industry: Size of Firms (2014)

Japan

Belgium

France Germany

USASwitzerland

Small Firms (<50 Employees) Large Firms (>50 Employees)

Nanotech Industry: Revenue (2010-2013)

Nan

otec

h Re

venu

e in

$U

SD B

illio

ns

• Restructuring of pricing models to constrain healthcare costs/increase access (e.g. Gilead’s three pricing tier with Sovaldi)

• Continued revamping of R&D/innovation processes including the development of more carefully crafted product pipelines

• Increased mergers and acquisitions to bolster R&D resources, integrate delivery models, and maintain global competitiveness

• Expansion and growth of biotech/nanotech market in the Asia-Pacific

• Growth of global biosimilars market and continued deliberation about generics and IPR

• Spread of nanotech into nontraditional sectors, creating more “nano-enabled” products

Predicted Future Industry Trends

• Immunotherapies and Nanomedicines

• Wearable Health Trackers/Personalized Medicine

• Epigenetics and Genome Editing

• Nanomaterials

• Big Data (Use of proliferating, ubiquitous data collection for future research on assuring nanotech/biotech quality, safety, and traceability)

Predicted R&D Focal Points

1. “Most Cited”: Web of Science ISI Citation Index Database (Accessed July 31, 2015) http://apps.webofknowledge.com/2. OECD Key Biotechnology Indicators and OCED 2014 Biotechnology Report (Accessed July 12, 2015) http://www.oecd.org/sti/inno/keybiotechnologyindicators.htm3. EY Beyond Borders: Reaching New Heights (29th Annual Biotech Industry Report; Accessed July 21, 2015)http://www.ey.com/GL/en/Industries/Life-Sciences/EY-beyond-borders-unlocking-value4. OECD Key Nanotechnology Indicators (Accessed July 14, 2015) http://www.oecd.org/sti/nanotechnology-indicators.htm5. Web of Science ISI Citation Index Database (Accessed July 31, 2015)http://apps.webofknowledge.com/6. US NSF/Lux Research (Accessed August 3, 2015)https://portal.luxresearchinc.com/research/report_excerpt/16215

References

National Consultative WorkshopStrengthening and Road Mapping of Emerging Technology Innovation Systems of Sri Lanka

17-19 November 2015 Colombo, Sri Lanka

Thank you

Mr. N. SrinivasanCoordinator, Science, Technology, and Innovation

Asian and Pacific Centre for Transfer of Technology (APCTT) of theUnited Nations Economic and Social Commission for Asia and the Pacific (UN ESCAP) in New Delhi, India