REFERATPENYAKIT GRAVESMaria Angeline ChristiantoNRP. 15221!"1#FAK$%TAS KE&'KTERAN$NIVERSITAS KAT'%IK (I&YA MAN&A%AS$RA)AYA2"15KELENJAR TIROIDT *an T! *isi+,an teri-at ,a*a,rotein.Gli-o,reotein tiroglo/0linPreal/0+inAl/0+in ser0+1an2a se*i-it T *an T! 2ang ti*a- teri-at ter*a,at *ala+ sir-0lasi *arahKELENJAR TIROIDSe-resiHORMON TIROIDIodide trappingTrans,or a-ti3 4*engan sti+0lasi TS15)erh0/0ngan *engan Na6 K6 ATPase sel 3oli-el +enari- 2o*i*a *ari *arah -e *ala+n2ao71""8"" 0g 2o*i*a 9 -e/0t0han sehari8hari'rgani:-asi'-si*asi 4oleh tiroi* ,ero-si*ase5. 2o*i*a 2o*i0+Yo*inasi. tirosin monoiodothyrosine 4MIT5 *an diiodothyrosine 4&IT5HORMON TIROIDCouplingMIT *an &IT T *an T! *i si+,an *ala+ -oloi*Se-resiA-ti;itas lisoso+ 4/ant0an en