great plains laboratory clinician manual

8/16/2019 Great Plains Laboratory Clinician Manual

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ClinicianInformation

ManualThe Great Plains Laboratory, Inc.

11813 W. 77th St.

Lenexa, Kansas 66214

[email protected]

www.GreatPlainsLaboratory.com

913-341-8949 Toll-Free 800-288-0383

Your Representative

___________________________________

Account Representative

___________________________________

Direct Line

___________________________________

Mobile

___________________________________

E-mail

Revised: 7 /13/20


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Clinician Information Manual

William Shaw, Ph.D., Director 11813 West 77th Street, Lenexa, KS 66214 (913) 341-8949 Fax (913) 341-6207 www.GPL4U.com

Getting Started with Lab Testing 1

■

Introduction to The Great Plains Laboratory, Inc.■ Test Kit Order Form

■ Additional Resources Available on Our Website

■ Brochures Available on Our Website

■ GPL3 and GPL4 Panels

Clinical Lab Test Recommendations 2

■ Top 5 Recommended Tests

■ Clinical Significance of the Organic Acids Test

Test & Pricing Information 3

■ Physician Test Price List

■ Patient Test Price List

■ Test Descriptions

Turn-Around Times and Specimen Collection 4

Insurance Billing, CPT & ICD-9 Codes 5

■ Insurance Overview■ Insurance Coverage Verification Guide

■ CPT Codes for Insurance Billing (Individual Tests & Test Panels)

■ ICD-9 Codes for Insurance Billing

Sample Test Requisition Form 6

Nutritional Supplements 7

■ Distributor Price List

■ New Client Form

Introduction to Integrative Medicine for Mental Health (IMMH) 8

■ Introduction to IMMH & IMMH Website

■ Recommended Testing for Mental Health Patients

■ Introduction to Zeebra Formulations

■ Practitioner Supplement Recommendations


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Getting Started With Lab Testing

Getting Started

With Lab Testing

Getting Started with Lab Testin


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Introduction to The Great Plains Laboratory, Inc.

Welcome to The Great Plains Laboratory, Inc., where customer service is our number one

priority. Our friendly staff is dedicated to helping both medical practitioners and patients to

achieve their maximum potential through accurate and informative laboratory testing. As a

client, you will appreciate the personal, one-on-one service that sets our laboratory apart fromthe rest. We hope you will take advantage of the new clinical tests we have to offer based on

the latest research.

Our laboratory staff works diligently with medical practitioners and individual patients to ensure

that test results are thoroughly understood. Our knowledgeable customer service

representatives are available by phone and by email to answer questions and to provide clear

advice about how to order our tests. Our clients receive the maximum value for their test

results, which includes a professional consultation.

At The Great Plains Laboratory, Inc., we have coupled advanced technology with friendly

assistance to offer the most complete, reliable, and understandable laboratory testing available.

We look forward to working with you soon.

Sincerely,

William Shaw, Ph.D.

Laboratory Director

Website: www.GPL4U.com

E-mail: [email protected]



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Kit Order Form Fax to: 913‐324‐5262

Quantity Test Kits Quantity Test Kits

Amino Acids Urine Test ‐ Random Collection Amino Acids Plasma Test (US only)

Amino Acids Urine Test ‐ 24 Hr Collection

Advanced Cholesterol Test

IgE Food Allergy Basic Test

IgE Inhalant Allergy Basic Test

Gluten / Casein Peptides Test

GPL‐TOX Profile

Metals Urine Test ‐ Random Collection

Microbial Organic Acids Test (MOAT)

Organic Acids Test (OAT)

Phospholipase A2 Activity Test

Uric Acid Test ‐ Random Collection

C‐

Reactive

Protein

Test

(hs‐

CRP)Celiac Disease Test

IgG Food Allergy Test w/ Candida

IgG Asian Food Allergy Test w/ Candida

IgE Food Allergy Essential (12) Test

IgG Food Allergy Test + IgE Food Allergy Essential (12) Test

Prealbumin Test

Streptococcus Antibodies Profile

Vitamin D Test ‐ Serum

Kryptopyrrole Test (US only) IgE Allergy Advanced Combined Test

Metals Urine Test ‐ 24 Hr or Timed Collection

Uric Acid Test ‐ 24 Hr Collection

IgE Food Allergy Advanced Test

IgE Inhalant Allergy Advanced Test

Porphyrins Test Ceruloplasmin Test

Copper / Zinc Profile

Comprehensive Fatty Acids Test (US & Canada only)

Comprehensive Stool Analysis IgG Food Allergy Test w/ Candida ‐ Dried Blood Spot (DBS)

IgG Asian Food Allergy Test w/ Candida (DBS)

Metals Fecal Test Immune Deficiency Profile

Yeast Culture w/ Sensitivity Test Metals Red Blood Cell Test

Metals Whole Blood Test

MOAT + Yeast Culture w/ Sensitivity Test Combo Vitamin D Test ‐ Dried Blood Spot (DBS)

OAT + Amino Acids Urine Test Combo Random ___ 24 hr ___

OAT + IgG Food Allergy Test w/ Candida ‐ DBS Combo

Hormones Comprehensive Panel

Hormones Comprehensive Plus Panel

Hormones Short Comprehensive Panel

OAT + IgG Food Allergy Test w/ Candida ‐ Serum Combo

OAT + Yeast Culture w/ Sensitivity Test Combo GPL Information Guides

GPL3: OAT + IgG Food Allergy Test ‐ DBS + Metals Hair Pediatric Collection Bags

GPL4‐DBS: OAT + IgG Food Allergy Test w/ Candida

+ Metals Hair + Phospholipase A2 Activity Tes

GPL4‐Serum: OAT + IgG Food Allergy Test w/ Candida

+ Red Blood Cell + Phospholipase A2 Activity Test Metals Hair Test

Comprehensive Autism Panel Basic Autism Panel

Comprehensive AD(H)D Panel Basic AD(H)D Panel

Comprehensive Tourette’s & Tics Panel Basic Tourette’s & Tics Panel

Comprehensive Fibromyalgia & CFS Panel Basic Fibromyalgia & CFS Panel

Comprehensive Wellness Panel Basic Wellness Panel

Comprehensive Mental Health Panel Basic Mental Health Panel

Clinic City, State & Zipcode:

Physician Phone:

Clinic Name: Physician Name:

Physician Fax:Physician Email:

Clinic Street Address:

Physician Title:

BASIC TEST PANELS

URINE KITS

STOOL KITS

BLOOD KITS

COMBO KITS

SALIVA KITS

OTHER MATERIALS

HAIR KIT

COMPREHENSIVE TEST PANELS


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Additional Resources Available on Our Website

Free Webinars

The Great Plains Laboratory, Inc. uses the power of the internet to bring educational conferences into the comfort of your

home. These webinars are educational seminars conducted by a wide range of experts on the topic of biomedical treatment

and testing. The information is designed to provide useful information about the clinical manifestations that occur in certain

disorders. The presenters draw from years of clinical experience to bring you important, helpful information about various

situations that can occur in the body to create illness and disease. The presentations explain the topic in detail using language

that is easy to understand. These live webinars are given frequently throughout the year. Specific dates can be found listed on

the Upcoming Webinars section of our home page.

Sign Up to Receive Email Updates

Emails will include information regarding new and updated tests, conferences, and webinars. A special publication called

BioMed Today E-Newsletter is sent out quarterly in addition to the e-mails and includes a featured topic and related

articles about new and updated discoveries in the biomedical field as well as upcoming events, discussions, tips, recent

news, and other resources. Visit E-mail Sign Up under Upcoming Events on our website to sign up.

Books and DVDsWe offer a variety of educational books and DVDs including Dr. Shaw’s books: “Biological Treatments for Autism and

PDD” and “Autism: Beyond the Basics.” To place an order, go to GPL Bookstore under Resources on our website.

Integrative Medicine for Mental Health (IMMH) Clinician Registry & Resources

Integrative medicine for mental health is a whole body approach utilizing multiple fields of medicine and nutritional

sciences. The Integrative Medicine for Mental Health website contains a Registry where medical professionals are listed

as resources to the community. Clinician Registry eligibility is exclusive to practitioners who have either attended an

IMMH Conference or after viewing the IMMH Conference DVD. Visit www.IMMH.org for more information.

Educational Conferences

The Great Plains Laboratory, Inc. regularly hosts, sponsors, and attends conferences around the world. These events

provide patients and practitioners with the opportunity to learn more about the latest research and the clinical significanceof tests and treatments. The conferences hosted by GPL provide an opportunity to learn about the complex metabolic

pathways that are affected in particular disorders, and about environmental and genetic influences that are contributing to

the symptoms of disease. To find out where GPL is participating in a conference, visit Upcoming Events on our website.

Clinician Educational Seminars

The Great Plains Laboratory, Inc. frequently hosts clinician educational seminars designed to improve the scope of

practice. We provide useful tools for practitioners to understand the various influences that complicate metabolic

pathways and explain the connection in our test results. Using the latest research on specific compounds and metabolites,

we bring new insight to the disease process. The practitioner will gain an understanding of the clinical significance of

biomedical testing and a clear comprehension of the appropriate treatment. To find out when and where our next clinician

educational seminar will be held, visit Upcoming Events on our website.

Sample Patient Health History Form

This is a template available for you to use to obtain patient information and assess overall health.

Four Weeks to Dairy-Free

This educational resource is to help those who are trying to embark on a casein-free (CF) or dairy-free diet. The guide

contains information on how to get started, a list of foods that contain casein and their alternatives, recipes, meal ideas,

and more. The daily instructions included in the guide can provide a smooth transition to a dairy-free lifestyle.

Patient Price List

This resource is available for download. When placing kit orders, you can request sets of 12 for waiting room material.



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This innovative and valuable panel by the Great Plains Laboratory (GPL) provides an

excellent and accurate description of the patient’s overall health in regards to their

metabolism, vitamins and mineral levels, food allergies and metal toxicity. Testing for

organic acids, IgG’s, food allergies and metals is crucial to detect any malfunctioning

within the body. With the GPL3 panel, no blood draw is required. Included in the panel ar

Organic Acids Test The Organic Acids Test (OAT) provides a metabolic “snapshot” based on the products the body

discards through the urine. These small, discarded organic acid molecules are byproducts of hum

cellular activity, the digestion of foods, and the metabolism of gastrointestinal flora. The Organic

Acids Test includes 74 urinary metabolites, including 9 yeast markers, 8 bacterial markers, 3 oxalat

markers, 3 Glycolytic cycle markers, 6 Krebs cycle markers, 7 neurotransmitter markers, 1 folate

metabolism markers, 8 fatty acid oxidation markers, 8 vitamin markers, 3 indicators of detoxificat

14 Amino Acid metabolites and 1 bone metabolite. This makes it the most comprehensive Organ

Acids test available anywhere.

IgG Dried Blood Spot - Food AllergiesIgG (immunoglobulin G) testing is a useful guide for structuring elimination diets in many chronic

conditions. Individuals with neurological, gastrointestinal, and movement disorders often suffer

from IgG food allergies. IgG Food allergies do not usually release histamine but cause inflamation

and elevated C-reactive protein. The 93 foods tested in the IgG Food Allergy Test w/ Candida can

identify problem foods so they can be eliminated from the patient’s diet.

Metals Hair The metals test is important for measuring toxic metals that can impede development and norm

brain functioning, as well as measuring levels of minerals essential for normal growth and goodhealth. The results indicate levels of 39 toxic and essential elements, 5 ratios and includes an

individualized interpretation.

Today, with increasing pollution levels, the presence of toxic metals in the environment is constan

growing. Chemical products, fertilizers, industrial paint, building materials, fish, silver dental filling

and vaccines are just some of the sources of heavy metals in everyday life. Toxic metals may norm

be present in the body in very low levels, but continuous exposure or metabolic abnormalities ca

cause accumulation of heavy metals in body tissues, and subsequently, in the brain.

Value for your money:Please call your GPL representative to inquire about the different billing options available for the GP

www.GPL4U.com [email protected] 913-341-8

AD(H)D

Allergies

Alzheimer’s Disease

Autism

Bipolar Disorder

Candida & Bacteria Overgrowth

Chemical Exposure

Chronic Fatigue

Depression

Digestive Disorders

Eating Disorders

Fibromyalgia

Multiple Sclerosis

OCD

Schizophrenia

Seizure Disorders

Tourette Syndrome

Tics disorders and more.

Recommended for the following conditions:Metal Toxicity

Food Intolerance

Gastrointestinal Imbalance



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The value of the GPL4 panel comes from the superior and comprehensive analysis it

provides from a single urine sample and 3 blood tube samples testing for organic acids,

vitamins and mineral levels, food allergies, metal toxicity and Vitamin D. The GPL4 panel

provides an excellent assessment of an individual’s metabolism and is targeted to find any

irregularities that are directly related to numerous conditions. Included in the panel are:

Organic Acids Test The Organic Acids Test (OAT) provides a metabolic “snapshot” based on the products the body

discards through the urine. These small, discarded organic acid molecules are byproducts of human

cellular activity, the digestion of foods, and the metabolism of gastrointestinal flora. The Organic

Acids Test includes 74 urinary metabolites, including 9 yeast markers, 8 bacterial markers, 3 oxalate

markers, 3 glycolytic cycle markers, 6 Krebs cycle markers, 7 neurotransmitter markers, 1 folate

metabolism markers, 8 fatty acid oxidation markers, 8 vitamin markers, 3 indicators of detoxification,14 amino acid metabolites and 1 bone metabolite. This makes it the most comprehensive Organic

Acids test available anywhere.

IgG - Food Allergies SerumIgG (immunoglobulin G) testing is a useful guide for structuring elimination diets in many chronic

conditions. Individuals with neurological, gastrointestinal, and movement disorders often suffer

from IgG food allergies. IgG Food allergies do not usually release histamine but cause inflamation

and elevated C-reactive protein. The 93 foods tested in the IgG Food Allergy Test w/ Candida can

identify problem foods so they can be eliminated from the patient’s diet.

RBC Metals* The Red Blood Cell (RBC) Test is an invaluable diagnostic method for assessing insufficiency or

excess of elements that have important functions within cells or on blood cell membranes. Analysisof red blood cells provides the best diagnostic tool for assessing the status of elements that have

important functions inside cells or on blood cell membranes. Our RBC test provides analysis of 13

essential elements and 5 toxic metals. It is highly recommended for checking levels of deficiency of

minerals and acute exposure to heavy metals.

* The Metals Hair Test is also offered in place of the RBC Metals Test for the Metals Toxicity section in the GPL4 Panel.

Vitamin D

Vitamin D is essential for the formation, growth, and repair of bones. Vitamin D is necessary for

normal calcium absorption and immune function. It also improves muscle strength and helps reduce

inflammation. The Vitamin D Test at The Great Plains Laboratory, Inc. measures both D2 and D3 and

can help to determine if sun exposure is adequate, if dietary vitamin D is sufficient, and to assess the

likelihood of malabsorption.

Value for your money:Please call your GPL representative to inquire about the different billing options available for the GPL4.

www.GPL4U.com [email protected] 913-341-8949

Food Intolerance

Vitamin D

Gastrointestinal Imbalance

Recommended for the following conditions:AD(H)D

Allergies

Alzheimer’s Disease

Autism

Bipolar Disorder

Candida & Bacteria Overgrowth

Chemical Exposure

Chronic Fatigue

Depression

Digestive Disorders

Eating Disorders

Fibromyalgia

Multiple Sclerosis

OCD

Schizophrenia

Seizure Disorders

Tourette Syndrome

Tics disorders and more.

Getting Started with Lab Testing


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Clinical Lab Test Recommendations

Clinical Lab Test

Recommendations

Clinical Lab Test Recommendation


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IgG Food Allergy Test w/Candida

GPL’s IgG Food Allergy Test identifies sensitivities to 93 foods, including those

commonly eaten as well as several that are used as substitutes for common

trigger foods. IgG antibodies have a much longer half life than the traditional

IgE allergy, and symptoms may occur hours or days after the offending food has

been consumed. Our test also detects IgG antibodies to Candida, a common

yeast species, at no additional charge. Candida overgrowth in the gut may

contribute to food allergies and sensitivities by allowing absorption of partially

digested proteins (peptides), triggering antibody production to foods.

IgG food allergy testing is beneficial for the following conditions: AD(H)D, asthma,

autism, autoimmune and inflammatory disorders, celiac disease, Crohn’s disease,

diabetes, fatigue, irritable bowel syndrome, migraines, obesity, rheumatoid

arthritis, sleep disorders, and many others.

Methodology

GPL uses an enzyme-linked immunosorbent assay (ELISA) method to measure IgG antibodies in human serum

and dried blood spots (DBS) against offending foods and Candida. The test as a DBS collection is a very easy and

convenient alternative for patients and practitioners who do not have access to a phlebotomist. The specimen can be

collected from the convenience of home and shipped to our laboratory for analysis.

Unlike most other laboratories that test food sensitivities based only on IgG4, GPL offers an affordable measure

of total IgG (IgG1, IgG2, IgG3, and IgG4), providing a more comprehensive and accurate representation of adverse

food-based reactions. IgG4 antibodies do not activate the immune factor termed “complement” and are incapable of

causing inflammation. Thus, total IgG analysis is far more clinically useful than IgG4 alone.

Quality Control

At the Great Plains Laboratory, we perform several different methods of quality controls toensure the accuracy and reliability of our IgG analysis. We perform a quality control check

using a positive control specimen on each coated micro titer plate lot before we ever put it into

production. By performing the control throughout the lot, we obtain a high level of precision.

To guarantee that there are no false positives reported, we run a no matrix specimen (buffer) on

each batch. Additionally, we incorporate 2 negative controls (no antigen) and 1 positive control

on each individual specimen that we run.

We utilize random split-sample testing by an independent laboratory to guarantee the accuracy

and reliability of our IgG panels. To date, all results have corresponded precisely to those obtained

by other, more expensive leading food and environmental allergy testing facilities.

GPL’s IgG Food Allergy Test results are provided in a semi-quantitative report which shows

sensitivities in a low, moderate, and high range versus results from other laboratories that are

shown in a yes / no report. Our results provide rotation diet recommendations with food optionsthat patients can use to prevent new food reactions.

Legumes - Beans and Peas

Garbanzo Bean 1.96

Green Bean 3.34

Kidney Bean 4.19

Lentil 1.28

Lima Bean 1.22

Pea 1.36

Pinto Bean 3.46

.

Wheat Gluten 4.34

Wheat 4.72

Fish

Cod Fish 1.79

Crab 0.99

Halibut 1.85

Lobster 1.49

Salmon 2.89

Reactivity Summary

HighEgg White Egg Yolk Candida Albicans

Milk Yeast, Bakers * Yeast, Brewers *

Whey Yogurt Casein

Cheese Beef Goat Cheese

Lemon Strawberry Sorghum

Moderate

Cranberry Wheat Mozzarella Cheese

Wheat Gluten Celery Kidney Bean

Grapefruit Lettuce Gliadin

Garlic Rye Millet

Peanut Barley Corn

Cocoa

Low

Pinto Bean Green Bean Lamb

Buckwheat Honey Mushroom

Chicken Salmon Sesame

Onion Tomato Pistachio

Watermelon Apple Pear

Pineapple Pecan Broccoli

Blueberry Carrot Cane Sugar

Banana Radish Potato

Eggplant Turkey Orange

Green Pepper Flax Spinach

Cabbage Cashews Oat

Grape Pumpkin Beet

.

. . .Top 5 Recommended Tests 201/08/14

William Shaw, Ph.D., Director 11813 West 77th Street, Lenexa, KS 66214 (913) 341-8949 Fax (913) 341-6207 www.GPL4U.comWilliam Shaw, Ph.D., Director 11813 West 77th Street, Lenexa, KS 66214 (913) 341-8949 Fax (913) 341-6207 www.GPL4U.com

Physician Name:Requisition #:

Patient Name: Date of Collection:

Timeof Collection:PatientAge:

Sex: Print Date:

Comprehensive IgG Food Allergy Test + C. albicans, S. cerevisiae (94)

Dairy

Casein 7.15

Cheese 7.05

Goat Cheese 5.91

Milk 9.39

Mozzarella Cheese 4.65

Whey 8.13

Yogurt 7.27

Legumes-Beansand Peas

Garbanzo Bean 1.96

Green Bean 3.34

Kidney Bean 4.19

Lentil 1.28

Lima Bean 1.22

Pea 1.36

Pinto Bean 3.46

Soybean 1.69

Fruit

Apple 2.60

Apricot 1.81

Banana 2.39

Blueberry 2.45

Coconut 1.96

Cranberry 4.90

Grape 2.06

Grapefruit 4.16

Lemon 5.40

Orange 2.25

Papaya 1.78

Peach 1.67

Pear 2.60

Pineapple 2.59

Plum (Prune) 1.69

Strawberry 5.33

Watermelon 2.66

Grains

Barley 3.61

Buckwheat 3.24

Corn 3.60

Gliadin 3.95

Millet 3.84

Oat 2.11

Rice 1.70

Rye 3.88

Sorghum 5.09

Wheat Gluten 4.34

Wheat 4.72

Fish

Cod Fish 1.79

Crab 0.99

Halibut 1.85

Lobster 1.49

Salmon 2.89

Sardine 1.30

Shrimp 0.99

Tuna 1.98

Meat/Fowl

Beef 6.39

Chicken 3.05

Egg White 13.63

Egg Yolk 12.91

Lamb 3.25

Pork 1.68

Turkey 2.26

Nutsand Seeds

Almond 1.86

Cashews 2.12

Flax 2.18

Hazelnut 1.45

Peanut 3.77

Pecan 2.56

Pistachio 2.66

Sesame 2.85

Testingperformedby TheGreat Plains Laboratory, Inc., Lenexa, Kansas. TheGreat Plains Laboratory has developedand determined

theperformancecharacteristics of this test. This test has not beenevaluatedby the U.S. FoodandDrugAdministration.

Dairy

Casein 7.15

Cheese 7.05

Goat Cheese 5.91

Milk 9.39

Mozzarella Cheese 4.65

Whey 8.13

Yogurt 7.27

Buckwh

Corn

Gliadin

Millet

Oat

Rice

Rye

Sorghu


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IgE Food & Inhalant Allergy TestsA “classic,” or Type I, allergy causes immediate reactions to foods/inhalants characterized by

redness, swelling, and heat in the body as a response to elevated blood levels of Immunoglobulin

E (IgE). The symptoms produced by IgE can be subtle and similar to those seen with other

immunoglobulins. GPL offers a serum-based IgE Food Allergy Test that analyzes either 25 (Basic)

or 93 foods (Advanced).

We offer an IgE Inhalant Test that analyzes 36 (Basic) or 69 inhalants (Advanced). The Advanced

IgE Inhalant Test increases the ability of the practitioner to identify numerous offending foods

and/or inhalants, including Thimerosal and Candida which are commonly associated with

neurological, gastrointestinal, and movement disorders.

The use of our IgE Food and Inhalant Allergy Tests can identify sources of allergic reaction to

reduce inflammation, asthma, hives, skin rashes, and other allergic reactions. Elimination ofIgE positive foods and inhalant exposure can bring major improvements in many symptoms or

disorders triggered by common allergens.

Our FDA-approved method of technology maximizes the ability to identify IgE-mediated allergy

response with high specificity and traceability to World Health Organization standards. We perform

several different methods of quality control to ensure the accuracy and reliability of our analysis.

Top 5 Recommended Tests 01/08/14


The Great Plains Laboratory is the only lab in the U.S. with an in-house opiate peptides method

that follows federal laboratory regulations. Our peptides test indicates an inability to completely

digest wheat, rye, barley, and milk proteins. Casomorphin is derived from dairy and gliadorphin

is derived from wheat and other gluten-contaminating grains. Individuals who have difficulty

digesting these opiate peptides may experience altered behavior, lack of focus, sleepiness, or

aggression after consumption. Studies show that intolerance to gluten is the cause of multiple

mental disorders, including schizophrenia.

The test indicates sensitivity even when a patient has no IgE- or IgG-mediated response to these

foods, and helps determine whether dietary modifications should be part of an integrated

treatment plan. If either of the peptide results is abnormal, both gluten (from gliadorphin) and

casein (from casomorphin) should be eliminated. Our Gluten/Casein Peptides Test uses the ELISA

method, which is highly specific to the nanogram level (one-billionth of a gram). To accomplish

this, casomorphin and gliadorphin are custom-synthesized to be able to define the very sensitive

standard curve that is required.

Clinical Lab Test Recommendation


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INTESTINAL MICROBIAL OVERGROWTH

Yeast and Fungal Markers

itramalic Acidevate c trama c ac s pro uce ma n y y acc aromyces spec es or rop on acter a overgrowt

High-potency, multi-strain probiotics may help rebalance GI flora.

5-Hydroxy-methyl-furoic AcidA metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription onatural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth levels.

3-Oxoglutaric AcidIndicates a possible yeast overgrowth in the GI tract. High-potency, multi-strain probiotics may help

rebalance GI flora.

Furan-2,5-dicarboxylic AcidA metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription o

natural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth levels.

Furancarbonylglycine

A metabolite produced by Aspergillus and possibly other fungal species in the GI tract. Prescription onatural antifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.

Tartaric Acid

Produced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinose

Antifungal treatment and high-potency, multi-strain probiotics may help rebalance GI flora.

rabinose

Produced by action of Candida hyaluronidase on the intercellular cement, hyaluronic acid. Oxidation

the hyaluronic acid breakdown by white blood cell hypochlorite produces tartaric acid and arabinoseAntifungal treatment and high-potency, multi-strain probiotics may help rebalance GI flora.

arboxycitric AcidElevated yeast/fungal metabolites indicate overgrowth in the GI tract. Prescription or naturalantifungals, along with high-potency, multi-strain probiotics, may reduce overgrowth.

Tricarballylic Acid

A chemical byproduct released from fumonisins during passage through the gastrointestinal tract.

Fumonisins are fungal toxins produced primarily by F. verticillioides. Elevated levels can be caused bythe intake of corn or corn-based food contaminated with fumonisins.

Bacterial Markers

Hippuric Acid

A bacterial product of phenylalanine metabolism. Most hippuric acid in urine is derived from microbi

breakdown of chlorogenic acid, a common substance found in beverages and in many fruits andvegetables. Higher levels indicate GI bacterial overgrowth that can be reduced with natural anti-

bacterial agents and/or high-potency, multi-strain probiotics.

2-Hydroxyphenylacetic AcidElevated 2-hydroxyphenylacetic acid is associated with intestinal bacteria overgrowth. High-potency,

multi-strain probiotics may help rebalance GI flora.

-Hydroxybenzoic Acid

A marker for intestinal dysbiosis. Results may also show elevated values as a result of ingestion of

foods such as jams and pie fillings containing paraben preservatives. The use of probiotics and the

exclusion of paraben-containing foods is the first treatment consideration.

-Hydroxyhippuric Acid

A glycine conjugate of 4-hydroxybenzoic acid, a metabolite of paraben preservatives. May be elevate

after exposure to paraben antimicrobials in certain foods and cosmetics. Intake of fruits containingpolyphenols rich in anthocyanins, flavonols, and hydroxycinnamates may increase this compound inthe urine. Avoid exposure to parabens.

DHPPA

(dihydroxyphenylpropionic acid)

DHPPA in urine indicates intake of chlorogenic acid, a common substance in beverages and many frui

and vegetables. Harmless or beneficial bacteria such as Lactobacilli, Bifidobacteria, and E. coli ncreasethe breakdown of chlorogenic acid to DHPPA, so high values are mainly associated with increasedamounts of these species in the GI tract.

William Shaw, Ph.D., Director 11813 West 77th Street, Lenexa, KS 66214 (913) 341-8949 Fax (913) 341-6207 www.GPL4U.

The following pages list the 74 metabolite markers of the Organic Acids Test. Included is the name of the metabolic marker, its clinicsignificance, and usual initial treatment.


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Clinical Significance of the Organic Acids Test 04/09/15

Clostridia Bacterial Markers

4-Hydroxyphenylacetic Acid A tyrosine metabolic product of GI bacteria. Elevated levels are associated with bacterial overgrowth

or small bowel disease. May also indicate celiac disease.

HPHPA (3-(3-hydroxyphenyl)-3-

hydroxypropionic acid)

n elevated value indicates an overgrowth of certain Clostridia bacteria in the GI tract includingC. sporogenes, C. caloritolerans, and C. botulinum. This metabolite is commonly elevated in autism,

psychiatric disorders, and GI disorders. This metabolite inhibits the enzyme dopamine-beta-hydroxylase, leading to a derangement of neurotransmitter balance.

4-Cresol

n elevated value indicates an overgrowth in the GI tract of C. diffi cile. s meta o te s common yelevated in autism, psychiatric disorders, and GI disorders. This metabolite inhibits the enzyme,

dopamine-beta-hydroxylase, leading to a derangement of neurotransmitter balance.

3-Indoleacetic Acid

3-Indoleacetic acid is a tryptophan byproduct of the following Clostridia species: C. stricklandii, C.ituseburense, C. subterminale, and C. putrefaciens. Very high amounts of this metabolite derived fromryptophan may indicate a depletion of tryptophan needed for other physiological functions.

OXALATE METABOLITES

Glyceric Acid Elevated in genetic hyperoxaluria type II. Normal values of glyceric acid rule out genetic causes of

significant elevation of oxalic acid in urine.

Glycolic AcidVery elevated in genetic hyperoxaluria type I. Normal values of glycolic acid rule out genetic causes ofsignificant elevation of oxalic acid in urine. This genetic disease can be confirmed by DNA testing at th

Mayo Clinic.

Oxalic AcidElevated oxalic acid may be associated with dysbiosis from Aspergillus, Penicillium, and possiblyCandida, or from high doses of vitamin C. If yeast or fungal markers are elevated, antifungal therapy

may reduce oxalates. Elevated oxalic acid may also result from anti-freeze (ethylene glycol) poisoning

GLYCOLYTIC CYCLE METABOLITES

Lactic Acid

Elevated by a number of nonspecific influences, such as vigorous exercise, bacterial overgrowth of the

GI tract, shock, poor perfusion, B-vitamin deficiency, mitochondrial dysfunction or damage, and anemia,among others. Tiglylglycine is a more specific indicator of mitochondrial dysfunction or damage. Thepossibility of an inborn error of metabolism increases when the lactic acid value exceeds 300 mmol/

mol creatinine. There are many inborn errors of metabolism that are present with elevated lactic acid,including disorders of sugar metabolism, pyruvate dehydrogenase deficiency, and mitochondrial

sor ers.

Pyruvic Acid

Elevated by a number of non-specific factors, including vigorous exercise, bacterial overgrowth of

he GI tract, shock, poor perfusion, B-vitamin deficiency, mitochondrial dysfunction or damage, andanemia, among others. High pyruvic acid indicates the possibility of an inborn error of metabolism

hen the value exceeds 100 mmol/mol creatinine.


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MITOCHONDRIAL MARKERS KREBS CYCLE METABOLITES

An elevated result may indicate a relative deficiency of riboflavin and/or coenzyme Q10. Alsoproduced by bacterial degradation of unabsorbed glutamine supplement. Low levels may indicate

the need for leucine/isoleucine supplementation. Suggest supplementation with riboflavin and/orcoenzyme Q10.

Fumaric Acid

Increased urinary fumaric acid may be due to impaired Krebs cycle function, a defect in the enzymefumarase, or in mitochondrial function. To support mitochondrial function, supplement withcoenzyme Q10, nicotinamide adenine dinucleotide (NAD+), L-carnitine and acetyl-L-carnitine,

riboflavin, nicotinamide, biotin, and vitamin E.

Malic Acid

Slightly elevated values usually indicate a higher need for nutrients such as niacin and coenzymeQ10. When malic acid is simultaneously elevated with citric, fumaric, and 2-ketoglutaric acids, amitochondrial energy pathway dysfunction is strongly suggested.

2-Oxoglutaric Acid

Increased values in urine may be due to dietary vitamin deficiencies or the intake of 2-ketoglutaric acas a supplement. The conversion of 2-oxoglutaric acid to succinyl-CoA requires coenzyme A (derived

from pantothenic acid), flavin adenine dinucleotide (FAD) derived from riboflavin, and thiamine.

conitic Acid

Aconitase, the enzyme that metabolizes citric and aconitic acids, is dependent upon glutathione.

Elevated in mitochondrial disorders (e.g. Complex I and Pierson Syndrome). Elevated aconitic acid maindicate an additional requirement for reduced glutathione.

itric Acid

Elevations may be due to increased intake of citric acid-containing foods or result from intestinalyeast-producing citric acid, or perhaps inhibiting the human citric acid cycle. Increased citric acid

may also indicate depletion of glutathione, which is required for the enzyme, aconitase to metabolizeboth aconitic and citric acids. If pyroglutamic acid values are low, consider supplements containingglutathione, or n-acetyl-cysteine.

MITOCHONDRIAL MARKERS AMINO ACID METABOLITES

3-Methylglutaric Acid

3-Methylglutaconic

Significant increase is due to a reduced ability to metabolize the amino acid, leucine. This abnormalityis found in the genetic disease, methylglutaconic aciduria and in mitochondrial disorders.

3-Methylglutaconic acid may also be elevated. Supplementation with coenzyme Q10, niacin,L-carnitine and acetyl-L-carnitine, riboflavin, nicotinamide, biotin, and vitamin E may be useful.

3-Hydroxyglutaric

Marker of glutaryl CoA dehydrogenase deficiency. This enzyme is involved in the breakdown of

lysine, hydroxylysine, and tryptophan, and is associated with the genetic disease, glutaric aciduriatype 1. Elevated 3-hydroxyglutaric acid may occur in combination with glutaric and glutaconic acids.

Symptoms of glutaryl CoA dehydrogenase deficiency are varied. Some individuals appear normal,while others display encephalopathy, autism, cerebral palsy, and additional neurological abnormalitie

Treatment includes adherence to a diet low in lysine and supplementation with carnitine.

NEUROTRANSMITTER METABOLISMPhenylalanine and Tyrosine Metabolites

HVA and VMA

HVA (homovanillic acid), a dopamine metabolite, and VMA (vanillylmandelic acid), a metabolite of

epinephrine and norepinephrine, are often elevated due to stress increasing catecholamine outputfrom the adrenal gland, or from lead toxicity. Elevated HVA may also result from the intake of L DOPA,dopamine, phenylalanine, or tyrosine, or due to Clostridia metabolites.

HVA/VMA Ratio

An elevated ratio is often the result of a decreased conversion of dopamine to norepinephrine by theenzyme, dopamine beta-hydroxylase. Inhibition of this enzyme is commonly caused by Clostridia by-

products, including HPHPA, 4-cresol, and 4-hydroxyphenylacetic acid.

Continued on the next page



25/80


PYRIMIDINE METABOLITES FOLATE METABOLISM

Uracil

Because folic acid is involved as a methyl donor in the conversion of uracil to thymine, elevated uracilmay indicate a defect in folic acid metabolism. Elevated uracil is found in about 10% of children with

autism.

T ymine

Slightly elevated urinary thymine has no clinical significance. High values are associated with

inflammatory diseases and cancer. Elevated pyrimidines and elevated thymine have been reported indihydropyrimidine dehydrogenase deficiency, a rare genetic disease, which has been associated withseizures and autism.

KETONE AND FATTY ACID OXIDATION

3-Hydroxybutyric Acid

cetoacetic Acid

Ketones, such as 3-hydroxybutyric and acetoacetic acids, are the end-products of rapid or excessive

fatty acid breakdown. Common causes of elevated ketones are prolonged fasting, protein malnutritionhigh fat diet, vitamin B12 deficiency, severe GI Candida overgrowth, and pulmonary infections.

-Hydroxybutyric Acid

A moderate urinary increase in 4-hydroxybutyric acid may be due to intake of dietary supplementscontaining 4-hydroxybutyric acid, also known as gamma-hydroxybutyric acid. Very high levels may

indicate the genetic disorder involving succinic semialdehyde dehydrogenase deficiency.

dipic Acid

Slightly elevated adipic acid may result from excessive ingestion of gelatin or other “junk” foodcontaining adipic acid as an additive. Elevated adipic acid may also indicate an abnormality in fatty

acid metabolism. Dietary supplements containing L-carnitine or L-acetyl-carnitine may be beneficial.

Suberic Acid

Sebacic Acid

Ethylmalonic Acid

Methylsuccinic Acid

Increased urinary products of the omega fatty acid metabolism pathway may be due to carnitine

deficiency, fasting, or increased intake of triglycerides from coconut oil, or some infant formulas. Veryelevated values may indicate a genetic disorder. Fatty acid oxidation defects are associated with

hypoglycemia and lethargy. Regardless of cause, intake of dietary supplements containing L-carnitineor acetyl-L-carnitine may improve clinical symptoms.

Tryptophan Metabolites

5-Hydroxyindoleacetic Acid

Metabolite of the neurotransmitter, serotonin. Elevated values may result from supplementingtryptophan or 5 hydroxy tryptophan (5-HTP). Low values may indicate inadequate production of the

neurotransmitter, serotonin. Often slightly elevated by ingestion of foods high in serotonin, such asavocado, banana, tomato, plum, walnut, pineapple, or eggplant. High values are found in carcinoidsyndrome.

Quinolinic Acid

Increased values in urine may be caused by various factors such as chronic inflammation frommicrobial infections, central nervous system degeneration, excessive tryptophan supplementation,

or even exposure to phthalates. Reduce excess quinolinic acid by eliminating tryptophansupplementation and also reduce exposure to infections and environmental pollutants. Brain damageinduced by quinolinic acid can be mitigated by supplements containing acetyl L-carnitine, melatonin,

, turmer c, an gar c.

Kynurenic Aci KYNA

The most common causes of elevated kynurenic acid are the use of tryptophan supplements and

the presence of chronic infections. Very high urine values are found in genetic disorders involvingkynureninase deficiency.

Quino inic Aci / 5-HIAA RatioA high ratio indicates excessive inflammation due to recurrent infections, excessive tryptophan intakeimmune overstimulation, excessive adrenal production of cortisol, or excessive exposure to phthalates


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NUTRITIONAL MARKERS

Methylmalonic Acid

(Vitamin B12)

Slightly elevated methylmalonic acid is commonly associated with vitamin B12 deficiency, or otherfactors such as pernicious anemia, GI bacterial metabolism, malabsorption, or gastroenteritis in very

young infants. Very elevated values may indicate a genetic disorder.

Pyridoxic Acid

(Vitamin B6)

A major metabolite of vitamin B6. High pyridoxic acid indicates high recent intake of vitamin B6.Because some individuals may require very high doses of vitamin B6, high values do not necessarily

indicate the need to reduce vitamin B6 intake. Low values are associated with low B6 status, highoxalates, and/or low neurotransmitters.

Pantothenic Acid

(Vitamin B5)

An essential vitamin (vitamin B5). High pantothenic acid indicates high recent intake of pantothenicacid. Since some individuals may require very high doses of pantothenic acid, high values do not

necessarily indicate the need to reduce pantothenic acid intake.

Glutaric Acid

Vitamin B2

Elevation indicates riboflavin deficiency (vitamin B2), a common factor in moderate urinary increases

of glutaric acid. Other possible factors include fatty acid oxidation defects and metabolic effects ofvalproic acid (Depakene), or celiac disease. The probability of a genetic disease is higher with very higvalues. The use of dietary supplements containing riboflavin and coenzyme Q10 may improve clinica

symptoms. This compound may be elevated in about 10% of children with autism.

Ascorbic Acid

(Vitamin C)

Commonly elevated by supplementation. High values are usually of no concern, except in individuals

w t extreme y g nta e > mg ay , n w om ascor c ac may e converte to oxa c ac ,increasing the risk of kidney stones. It is unlikely that elevated vitamin C will contribute to kidney

stone formation if oxalic acid is in the normal range.

3-Hydroxy-3-methylglutaric Acid

(Coenzyme Q10)

The precursor of coenzyme Q10 and cholesterol. Slightly increased values may be caused bygastrointestinal yeast overgrowth. A moderate increase in urine HMG may also indicate decreasedsynthesis of coenzyme Q10. Certain cholesterol-lowering drugs may inhibit the synthesis pathway anresult in high HMG values. Very elevated values may be caused by the genetic disorder, HMG aciduria

N-Acetylcysteine Acid

A powerful antioxidant that increases the glutathione reserves in the body. Together with glutathioneacetylcysteine directly binds to toxic metabolites. Although acetylcysteine may be beneficial undercertain conditions, excessive use of the supplement could be harmful.

Methylcitric Acid

Biotin Vitamin H

Elevation usually indicates a biotin deficiency (Vitamin H). Biotin deficiency may be due tomalabsorption, excessive intake of raw egg white, dietary deficiency, or dysbiosis. Higher levels mayindicate the presence of genetic disorders involving biotin-dependent enzymes and may require biotsupplementation at very high doses.

INDICATORS OF DETOXIFICATION

Glutathione

Pyroglutamic Acid

Pyroglutamic acid is a metabolite of glutathione. Glutathione serves as an antioxidant and is also

conjugated to toxic compounds in the liver. Elevated values are most commonly caused by glutathiondeficiency due to toxic exposure, such as acetaminophen toxicity. Elevated pyroglutamic acid may

also result from a genetic disorder, metabolic effects of certain antibiotics, or intake of certain infantformulas. Supplementation with liposomal glutathione or N-acetyl-cysteine can raise glutathione

levels. Selenium is essential to the antioxidant activity of glutathione; usually, adequate selenium canbe obtained from a quality multivitamin.

2-Hy roxy utyric Aci

Elevated 2-hydroxybutyric acid is a byproduct of the breakdown of the sulfur amino acid metabolite,

cystathionine, which may be formed in excess during oxidative stress or when toxic exposures increasthe need for detoxification. When glutathione is depleted by excessive toxic exposure, pyroglutamic

acid may also be elevated. High values of 2-hydroxybutyric acid may also be associated with the onsetof diabetes mellitus or significant alcohol intake. This compound may also be elevated in certain

genetic diseases such as lactic acidosis, glutaric aciduria type II, dihydrolipoyl dehydrogenase (E3)deficiency, and propionic aciduria.

Continued on the next page



27/80

Ammonia Excess

Orotic Acid

Elevations are most commonly associated with ammonia toxicity. Elevated ammonia may result fromdrug toxicity to the liver, viral liver infection, gastrointestinal bleeding, or inborn errors of ammonia

metabolism. Confirmation of a genetic disorder requires testing plasma amino acids.

Aspartame, Salicylates, or GI bacteria

2-Hydroxyhippuric Acid

conjugate of the amino acids, glycine and hydroxybenzoic acid (salicylic acid). Intake of aspirin

(salicylates) or the growth of salicylate-producing gastrointestinal bacteria may elevate levels. Alsoincreased after the ingestion of the artificial sweetener, aspartame (Nutrasweet).

AMINO ACID METABOLITES

2-Hy roxyisova eric Aci2-Oxoisovaleric Acid3-Methyl-2-oxovaleric Acid2-Hydroxyisocaproic Acid2-Oxoisocaproic Acid

moderate increase of branched-chain amino acid metabolites in urine may result from lactic acidosiepisodic ketosis, or deficiencies of the vitamins, thiamine or lipoic acid. Elevated 2-hydroxyisocaproic

acid in urine has also been linked to short bowel syndrome. A significant increase of branched-chainamino acid metabolites is associated with the genetic disorders, maple syrup urine disease (MSUD)

and pyruvate dehydrogenase deficiency. Patients with slight to moderate elevations may use dietary

supplements containing thiamine to improve clinical symptoms.

2-Oxo-4-methiolbutyric AcidElevated in an inborn error of methionine metabolism. Confirmation of the genetic disorder requires

esting of plasma amino acids.

Mandelic Acid

ncrease y etary p eny a an ne or p eny a an ne supp ementat on, ut a so ue to exposureo styrene, a toxic environmental compound. Significant elevation is found in the genetic disorder,

phenylketonuria (PKU). A plasma phenylalanine test will rule out PKU.

Phenyllactic Acid

metabolite of phenylalanine. Elevated values indicate increased intake of dietary phenylalanine or

he heterozygous carrier status (homozygosity) for the genetic disease, phenylketonuria (PKU). Valuesobserved in clinically diagnosed PKU typically exceed 200 mmol/mol creatinine.

Phenylpyruvic Acid

Moderate elevations may result from intake of phenylalanine, from genetic carrier status for PKU, orrom a deficiency in production of biopterin, a cofactor required for phenylalanine metabolism. Very

high values are associated with the genetic disease, PKU.

Homogentisic AcidHomogentisic acid is elevated in the genetic disorder, homogentisic aciduria (alkaptonuria). Slightincreases may indicate the heterozygous genetic carrier state of the disease.

4-Hydroxyphenyllactic Acid

Increased values are commonly associated with tyrosinemias, which can result from immature

development of enzyme synthesis in infants or genetic deficiencies. Slight increases may be due toincreased tyrosine intake, bacterial gut metabolism, short bowel syndrome, or liver disease.

N-Acetylaspartic AcidElevated N-acetylaspartic acid is due to the genetic disorder, Carnavan’s disease, a potentially fataldisease causing spongy degeneration of the brain.

Malonic Acid

ssociated with the genetic disorders, malonyl-CoA decarboxylase deficiency and malonic aciduriaith normal malonyl-CoA decarboxylase activity. Slightly elevated values in urine are unlikely to be

clinically significant.

MINERAL METABOLITES

Phosphoric Acid

Phosphate urinary excretion is directly proportional to dietary intake. Processed foods high inphosphate include: sodas, candy, ice cream, chocolate, mayonnaise, frozen pizza, commercially baked

goods, and meats. Excess phosphate is also associated with hyperparathyroidism, vitamin D-resistantrickets, immobilization following paraplegia or fracture due to bone resorption, vitamin D intoxication

blood lead levels above 1.5 ppm, renal tubular damage, familial hypophosphatemia, and metabolicacidosis. Low urinary phosphate is most common in low phosphate intake and in vitamin D deficiency.



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Test & Pricing Information

Test & Pricing

Information

Test & Pricing Information


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31/80

Physician Price List

Nutritional, Environmental, and Metabolic Assessments Physician Billing

Price*

Patient Cash

Price** List Price***

Out-of-Network

Payment***

Organic Acids Test (OAT) (74) – Urine $239 $299 $599 $120

Microbial Organic Acids Test (MOAT) (21) – Urine $159 $199 $449 $90

Advanced Cholesterol Profile – Serum $85 $110 $135 $27Amino Acids Test - Plasma or Urine (24 hr. or Random) (43) $199 $229 Insurance Not Availabl

C-Reactive Protein Test (hs-CRP) – Serum $55 $70 $85 $17

Ceruloplasmin Test – Serum $60 $85 $95 $19

Comprehensive Fatty Acids Test – Serum $209 $239 $299 $60

GPL-TOX (Toxic Organic Chemical Profile) (when ordered w ith t he OAT/MOAT) $199 ($149) $219 ($169) Insurance Not Availabl

Kryptopyrrole Test – Urine $129 $129 Insurance Not Availabl

Phospholipase A2 Activi ty Test (PLA2) (when ordered wi th t he OAT/MOAT) $99 ($39) $99 ($39) Insurance Not Availabl

Prealbumin Test – Serum $55 $70 $85 $17

Uric Acid Test (24 hr. or Random) – Urine (when ordered w ith t he OAT/MOAT) $65 ($29) $65 ($29) $85 ($39) $17 ($8)

Vitamin D Test – Serum or Dried Blood Spot (DBS) $48 $58 $99 $20

DNA Methylation Pathway

Physician Billing

Price*

Patient Cash


Out-of-Network

Payment***

DNA Methylation Pathway Profile – Dried Blood Spot (DBS) $429 $459 Insurance Not Availabl

Stool Tests Physician Billing

Price* Patient Cash


Out-of-Network

Payment***

Comprehensive Stool Analysis with Parasitology $295 $345 $599 $92

Yeast Culture w/ Sensitivity Test $140 $170 $225 $45

Hormone Tests Physician Billing

Price*

Patient Cash


Out-of-Network

Payment***

Hormones Comprehensive Panel $215 $225 $255 $51

Hormones Comprehensive Plus Panel $225 $275 $325 $65

Hormones Short Comprehensive Panel $195 $215 $225 $45

Food Allergies, Sensitivities, and Immune System Physician Billing

Price* Patient Cash


Out-of-Network

Payment***

gG Food Allergy Test w/ Candida (94) – Serum or Dried Blood Spot (DBS) $165 $219 $325 $65

gG Asian Food Allergy Test w/ Candida (94) – Serum or Dried Blood Spot (DBS) $165 $219 $325 $65

Celiac Disease Test – Serum $85 $109 $165 $33

Gluten / Casein Peptides Test – Urine $85 $110 $119 $24

gE Allergy Advanced Combined Test (93 / 69) – Serum $700 $729 $800 $160

gE Food Allergy Essentials Test (12) – Serum $75 $75 $119 $24

gE Food Allergy Basic Test (25) – Serum $219 $270 $379 $76

gE Food Allergy Advanced Test (93) – Serum $449 $479 $579 $116

gE Inhalant Allergy Basic Test (36) – Serum $219 $270 $379 $76

gE Inhalant Allergy Advanced Test (69) – Serum $349 $379 $449 $90

mmune Deficiency Profile – Serum $179 $239 $299 $60

Streptococcus Antibodies Profile – Serum $55 $70 $85 $17

Metals and Essential Elements Physician Billing

Price* Patient Cash

Price**List Price***

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Payment***

Metals Hair Test (39) $115 $140 $250 $50

Copper Test – Serum $35 $35 $60 $12

Copper / Zinc Profile – Serum $135 $165 $215 $43

Metals Fecal Test (13) $115 $140 $250 $50

Metals Red Blood Cell Test (18) $235 $285 $360 $72

Metals Urine (24 hr., Timed or Random) Test (37) $165 $185 $299 $60

Metals Whole Blood Test (20) $180 $210 $320 $64

Porphyrins Profile – Urine $85 $109 $145 $29

Zinc Test – Serum $35 $35 $60 $12


32/80

Revised 07/10/

Combo Tests Physician Billing

Price*

Patient Cash


Out-of-Network

Payment**

OAT + Amino Acids Urine Test Combo – Urine $425 $515 $899 $180

OAT + IgG Food Allergy Test w/ Candida Combo – Urine & Serum or Dried Blood SpotDBS)

$399 $499 $699 $140

OAT + Yeast Culture w/ Sensitivity Test Combo – Urine & Stool $319 $399 $699 $140

MOAT + Yeast Culture w/ Sensitivity Test Combo – Urine & Stool $239 $299 $549 $110

GPL3: Organic Acids Test + Metals Hair + IgG Dried Blood Spot (DBS) $514 $559 $949 $190

GPL4-DBS: Organic Acids Test + IgG Food Allergy Test + Metals Hair + Phospholipase A2 Activity Test

$562 $599 $1048 $210

GPL4-Serum: Organic Acids Test + IgG Food Allergy Test + Red Blood Cell +

Phospholipase A2 Activity Test$682 $699 $1,158 $232

gG Food Allergy Test w/ Candida + IgE Food Allergy Essentials Test – Serum $225 $279 $444 $89

Test Panels Physician Billing Price*Patient Cash


Out-of-Networ

Payment*

Comprehensive Autism Panel

$1,495 $1,835 $2,599 $492Advanced Cholesterol ProfileComprehensive Stool AnalysisCopper / Zinc ProfileFerritin Test

Gluten / Casein Peptides TestIgG Food Allergy Test w/ CandidaImmune Deficiency ProfileMetals Hair Test

Organic Acids TestStreptococcus Antibodies ProfileVitamin D Test

Basic Autism Panel $894 $1,094 $1,667 $305Comprehensive Stool Analysis

Gluten / Casein Peptides TestIgG Food Allergy Test w/ CandidaMetals Hair Test

Organic Acids Test

Comprehensive AD(H)D Panel

$1,716 $2,070 $3,124 $597Advanced Cholesterol ProfileAmino Acids Urine TestComprehensive Fatty Acids Test

Comprehensive Stool Analysis

Copper / Zinc ProfileFerritin TestGluten / Casein Peptides Test


Metals Hair TestOrganic Acids Test Streptococcus Antibodies Profile

Vitamin D Test

Basic AD(H)D Panel $808 $988 $1,367 $273Comprehensive Fatty Acids Test

Gluten / Casein Peptides TestIgG Food Allergy Test w/ CandidaMetals Hair Test

Organic Acids Test

Comprehensive Tourette’s & Tics Panel

$1,686 $2,070 $3,124 $597Advanced Cholesterol ProfileAmino Acids Urine TestComprehensive Stool AnalysisCopper / Zinc Profile

Ferritin TestGluten / Casein Peptides TestIgG Food Allergy Test w/ Candida Immune Deficiency Profile

Metals Hair TestOrganic Acids TestStreptococcus Antibodies ProfileVitamin D Test

Basic Tourette’s & Tics Panel$753 $918 $1,268 $254Advanced Cholesterol Profile

Ferritin TestIgG Food Allergy Test w/ Candida Metals Hair Test

Organic Acids TestStreptococcus Antibodies Profile

Comprehens ive Fibromyalgia & CFS Panel

$1,188 $1,457 $2,376 $447Amino Acids Urine TestC-Reactive Protein TestComprehensive Stool Analysis

Gluten / Casein Peptides TestIgG Food Allergy Test w/ Candida Metals Hair Test

Organic Acids TestVitamin D Test

Basic Fibromyalg ia & CFS Panel $599 $749 $1,068 $214Gluten / Casein Peptides Test

gG Food Allergy Test w/ Candida Metals Hair TestOrganic Acids Test

Comprehensive Wellness Panel

$1,366 $1,655 $2,440 $488Advanced Cholesterol ProfileAmino Acids Urine TestComprehensive Fatty Acids TestCopper / Zinc Profile

Ferritin TestGluten / Casein Peptides TestIgG Food Allergy Test w/ CandidaMetals Hair Test


Basic Wellness Panel $723 $878 $1,248 $250Comprehensive Fatty Acids Test

gG Food Allergy Test w/ Candida Metals Hair TestOrganic Acids Test

Comprehens ive Mental Health Panel

$1,570 $1,895 $2,714 $515Advanced Cholesterol ProfileAmino Acids Plasma TestComprehensive Fatty Acids TestComprehensive Stool Analysis

Copper / Zinc ProfileGluten / Casein Peptides TestIgG Food Allergy Test w/ Candida Metals Hair Test


Basic Mental Health Panel $1,007 $1,217 $1,666 $333Amino Acids Plasma Test

Comprehensive Fatty Acids Test



Metals Hair Test

Organic Acids Test

* Physician billing is unavailable in New Jersey and Rhode Island.** Payment must be submitted with sample. We accept checks, money orders, wire transfers, and all major credit cards.*** Price commonly billed to insurance. See insurance section on website or Test Requisition Form for exceptions.**** Out-of-network down payment (approx. 20% of list price) due upon submission (no up-front payment for in-network billing: some BCBS, Tricare, and Medicare). All prices are subject to change without prior notice.


33/80

Patient Price Lis t

Nutritional, Environmental, and Metabolic Assessments Cash Price* List Price** Out-of-Network Down

Payment***

Organic Acids Test (OAT) (74) – Urine $299 $599 $120

Microbial Organic Acids Test (MOAT) (21) – Urine $199 $449 $90

Advanced Cholesterol Profile – Serum $110 $135 $27

Amino Acids Test – Plasma or Urine (24 hr. or Random) (43) $229 Insurance Not Available

C-Reactive Protein Test (hs-CRP) – Serum $70 $85 $17

Ceruloplasmin Test – Serum $85 $95 $19

Comprehensive Fatty Acids Test – Serum $239 $299 $60

GPL-TOX (Toxic Organic Chemical Profil e) (when ordered w ith the OAT/MOAT) $219 ($169) Insurance Not Available

Kryptopyrrole Test – Urine $129 Insurance Not Available

Phospholipase A2 Activi ty Test (PLA2) (when ordered w ith the OAT/MOAT) $99 ($39) Insurance Not Available

Prealbumin Test – Serum $70 $85 $17

Uric Acid Test (24 hr. or Random) – Urine (when ordered w ith t he OAT/MOAT) $65 ($29) $85 ($39) $17 ($8)

Vitamin D Test – Serum or Dried Blood Spot (DBS) $58 $99 $20

DNA Methylation Pathway Cash Price* List Price** Out-of-Network Down

Payment***

DNA Methylation Pathway Profile – Dried Blood Spot (DBS) $459 Insurance Not Available

Stool Tests Cash Price* List Price** Out-of-Network Down

Payment***

Comprehensive Stool Analysis with Parasitology $345 $599 $92

Yeast Culture w/ Sensitivity Test $170 $225 $45

Hormones Tests Cash Price* List Price** Out-of-Network Down

Payment***

Hormones Comprehensive Panel $225 $255 $51

Hormones Comprehensive Plus Panel $275 $325 $65

Hormones Short Comprehensive Panel $215 $225 $45

Food Allergies, Sensitivities, and Immune System Cash Price* List Price** Out-of-Network Down

Payment***

IgG Food Al lergy Test w/ Candida (94) – Serum or Dried Blood Spot (DBS) $219 $325 $65

IgG Asian Food Allergy Test w/ Candida (94) – Serum or Dried Blood Spot (DBS) $219 $325 $65

Celiac Disease Test – Serum $109 $165 $33

Gluten / Casein Peptides Test – Urine $110 $119 $24

IgE Allergy Advanced Combined Test (93 / 69) – Serum $729 $800 $160

IgE Food Allergy Essentials Test (12) – Serum $75 $119 $24

IgE Food Allergy Basic Test (25) – Serum $270 $379 $76

IgE Food Allergy Advanced Test (93) – Serum $479 $579 $116

IgE Inhalant Allergy Basic Test (36) – Serum $270 $379 $76

IgE Inhalant Allergy Advanced Test (69) – Serum $379 $449 $90

Immune Deficiency Profile – Serum $239 $299 $60

Streptococcus Antibodies Profile – Serum $70 $85 $17

Metals and Essential Elements Cash Price* List Price** Out-of-Network Down

Payment***

Metals Hair Test (39) $140 $250 $50

Copper Test – Serum $35 $60 $12

Copper / Zinc Profile – Serum $165 $215 $43

Metals Fecal Test (13) $140 $250 $50

Metals Red Blood Cell Test (18) $285 $360 $72

Metals Urine (24 hr., Timed or Random) Test (37) $185 $299 $60

Metals Whole Blood Test (20) $210 $320 $64

Porphyrins Profile – Urine $109 $145 $29

Zinc Test – Serum $35 $60 $12


34/80

Revised 07

Combo Tests Cash Price* List Price** Out-of-Network Down Paymen

OAT + Amino Acids Urine Test Combo – Urine $515 $899 $180

OAT + IgG Food Allergy Test w/ Candida Combo - Urine & Serum or Dried Blood Spot (DBS) $499 $699 $140

OAT + Yeast Culture w/ Sensitivity Test Combo – Urine & Stool $399 $699 $140

MOAT + Yeast Culture w/ Sensitivity Test Combo – Urine & Stool $299 $549 $110

GPL3: Organic Acids Test + Metals Hair + IgG Dried Blood Spot (DBS) $559 $949 $190

GPL4-DBS: Organic Acids Test + IgG Food Allergy Test + Metals Hair + Phospholipase A2 Activity Test $599 $1048 $210

GPL4-Serum: Organic Acids Test + IgG Food Allergy Test + Red Blood Cell + Phospholipase A2 Activity Test

$699 $1,158 $232

IgG Food Allergy Test w/ Candida + IgE Food Allergy Essentials Test – Serum $279 $444 $89

Test Panels Cash Price* List Price** Out-of-Network Down Paymen

Comprehensive Aut ism Panel:

$1,835 $2,599 $492 Advanced Cholesterol ProfileComprehensive Stool AnalysisCopper / Zinc ProfileFerritin Test

Gluten / Casein Peptides TestIgG Food Allergy Test w/ Candida Immune Deficiency ProfileMetals Hair Test

Organic Acids TestStreptococcus Antibodies ProfileVitamin D Test

Basic Autism Panel $1,094 $1,667 $305Comprehensive Stool Analysis

Gluten / Casein Peptides TestMetals Hair TestIgG Food Allergy Test w/ Candida

Organic Acids Test

Comprehensi ve AD(H)D Panel

$2,070 $3,124 $597 Advanced Cholesterol Profile Amino Acids Urine TestComprehensive Fatty Acids TestComprehensive Stool Analysis

Copper / Zinc ProfileFerritin TestGluten / Casein Peptides TestIgG Food Allergy Test w/ Candida

Metals Hair TestOrganic Acids TestStreptococcus Antibodies ProfileVitamin D Test

Basic AD(H)D Panel $988 $1,367 $273Comprehensive Fatty Acids Test

Gluten / Casein Peptides TestMetals Hair TestOrganic Acids Test


Comprehensive Tourette’s & Tics Panel

$2,070 $3,124 $597 Advanced Cholesterol Profile Amino Acids Urine TestComprehensive Stool AnalysisCopper / Zinc Profile

Ferritin TestGluten / Casein Peptides TestIgG Food Allergy Test w/ Candida Immune Deficiency Profile

Organic Acids TestStreptococcus Antibodies ProfileVitamin D TestMetals Hair Test

Basic Tourette’s & Tics Panel $918 $1,268 $254 Advanced Cholesterol Profile

Ferritin TestMetals Hair TestOrganic Acids Test

IgG Food Allergy Test w/ CandidaStreptococcus Antibodies Profile

Comprehensi ve Fibromyalgia & CFS Panel

$1,457 $2,376 $447 Amino Acids Urine TestC-Reactive Protein TestComprehensive Stool Analysis

IgG Food Allergy Test w/ CandidaMetals Hair TestOrganic Acids Test


Vitamin D Test

Basic Fibromyalg ia & CFS Panel $749 $1,068 $214Gluten / Casein Peptides Test


Comprehensive Wellness Panel

$1,655 $2,440 $488 Advanced Cholesterol Profile Amino Acids Urine TestComprehensive Fatty Acids TestCopper / Zinc Profile

Ferritin TestGluten / Casein Peptides TestIgG Food Allergy Test w/ Candida

Metals Hair TestOrganic Acids TestVitamin D Test

Basic Wellness Panel $878 $1,248 $250Comprehensive Fatty Acids Test


Comprehensi ve Mental Health Panel

$1,895 $2,714 $515

Advanced Cholesterol Profile

Amino Acids Plasma TestComprehensive Fatty Acids TestComprehensive Stool Analysis

Copper / Zinc Profile

Gluten / Casein Peptides TestIgG Food Allergy Test w/ Candida

Metals Hair Test


Basic Mental Health Panel $1,217 $1,666 $333 Amino Acids Plasma Test

Comprehensive Fatty Acids TestIgG Food Allergy Test w/ Candida Metals Hair Test

Gluten / Casein Peptides TestOrganic Acids Test

All prices are subject to change without prior notice.* Payment must be submitted with sample. We accept checks, money orders, wire transfers, and all major credit cards.** Price commonly billed to insurance. Some BCBS plans are not considered in-network, see insurance section on website or Test Requisition Form for exception*** Out-of-network down payment (approx. 20% of list price) due upon submission (no up-front payment for in-network billing: some BCBS, Tricare, and Medicare


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Test / Turn Around Time DescriptionAdvanced Cholesterol Prof ile

- 4 weeks Total cholesterol, Apolipoprotein A-1 (Apo A-1), Apolipoprotein B (Apo B), Lipoprotein (a) (Lp (a)), Homocysteine

Amino Acid s Uri ne Test (43)

Amino Acids Plasma Test (43)

- 4 weeks

Alanine, Beta-Alanine, Alpha-Aminoadipic, Alpha-Aminobutyric, Gamma-Aminobutyric, Beta-Aminoisobutyric, Ammonia, Anserine, Arginine, Asparagine,Carnosine, Citrulline, Cystathionine, Cysteine, Cystine, Ethanolamine, Glycine, Glutamic, Glutamine, Histidine, Homocysteine, Hydroxyproline, IsoleucineLeucine, Lysine, Met Sulfoxide, Methionine, 1-Methylhistidine, 3-Methylhistidine, Ornithine, Phenylalanine, Phosphoethanolamine, Phosphoserine, Prolin

Sarcosine, Serine, Taurine, Threonine, Tryptophan, Tyrosine, Valine, Urine Only – Creatinine and Urea

C-Reactive Protein Test (hs-CRP)- 3 weeks

High Sensitivity C-Reactive Protein

Celiac Disease Test (2 - 4 weeks) Transglutaminase Antibody, Confirmatory test for Celiac Disease

Ceruloplasmin Test (1 - 3 weeks) Ceruloplasmin

Comprehensive Fatty Aci ds Test- 3 weeks

Total Saturated, Total Monounsaturated, Total Polyunsaturated, Total Omega 3, Total Omega 6, Total Fatty Acids. Omega 3 Series: Alpha-Linolenic,Eicosapentaenoic, Docosapentaenoic, Docosahexaenoic. Omega 6 Series: Linoleic, Gamma-Linolenic, Dihomo-Gamma-Linolenic, Arachidonic,Docosapentaenoic, Docosatetraenoic. Omega 9 Series: Eicosatrienoic. Monosaturated Series: Lauroleic, Myristoleic, Palmitoleic, Hexadecenoic, VaccOleic, Nervonic. Saturated: Caprylic, Lauric, Myristic, Palmitic, Stearic, Arachidic, Docosanoic, Tetracosanoic, Hexacosanoic. Branched-chain: PristanicPhytanic. Ratios: Triene-to-Tetraene.

Comprehensive Stool Analysis - 4 weeks

Bacterial culture: 73 potential species of imbalanced and dysbiotic bacteria, 4 species of beneficial bacteria. Yeast (Mycology) cu lture: 48 potential yefungal species. Parasite isolation: 22 potential parasites. Digestion and Absorption markers: Elastase, Fat Stain, Muscle Fibers, Vegetable fibers, anCarbohydrates. Inflammation markers: Lysozyme, Lactoferrin, White Blood Cells, Mucus. Immunology: Secretory Immunoglobulin A (sIgA). Short Ch

Aci ds: Acetate, Propionate, Butyrate, Valerate. Intestinal Health markers: Red Blood Cells, pH, Occult Blood, Yeast (microscopy). Yeast sensitivity tFluconazole, Itraconazole, Nystatin, Flucytosin, Berberine, Caprylic acid, Uva Ursi, Goldenseal, Tanalbit, Oregano. Bacterial sensitivity to: Augmentin,

Cefpodoxime, Cefuroxime, Ciprofloxacin, Tetracycline, Trimeth-sulfa, Berberine, Black Walnut, Caprilic Acid, Cats Claw, Goldenseal, Mastica, Oregano, UCopper Test (1 - 3 weeks) Copper

Copper / Zinc Profile (1 - 3 weeks) Bound Copper, Unbound Copper, Total Copper, Zinc, Ceruloplasmin

DNA Methylation Pathway Profile– 6 weeks

ACAT / 1-02, AHCY 1/2/19, BHMT 1, 3, 4, 8, CBS C699T/ A360A/ N212N, COMT V158M, H62H, 61, MAO A/ R297R, MTHFR C677T/A1298C/3, MTR/ AMTRR, A66G/H595Y/K350A/R415T/S257T/11, NOS / D298E, SHMT/ C1420T, SUOX/ S370S, VDR Taq1/ Fok1

Gluten / Casein Peptides Test- 2 weeks

Gliadorphin (peptide from wheat) and Casomorphin (peptide from dairy products)

GPL3 (2 - 3 weeks) See Organic Acids Test (OAT) (74), Metals Hair Test (39) and IgG Food Allergy Test w/ Candida (94)

GPL4-DBS (2 - 3 weeks) See Organic Acids Test (OAT) (74), IgG Food Allergy Test w/ Candida (94), Metals Hair Test (39) and Phospholipase A2 Activity

GPL4-Serum (2 - 3 weeks) See Organic Acids Test (OAT) (74), IgG Food Allergy Test w/ Candida (94), Metals Red Blood Cell Test (18) and Phospholipase A2 Activity

GPL-TOX (11) (1 – 2 weeks) 2-,3-,4-Methylhippuric Acid (2MHA, 3MHA,4MHA), 2,4-Dichlorophenoxyacetic Acid (2,4D), 2-Hydroxyisobutyric Acid (2HIB), 3-Phenoxybenzoic Acid (3PBDiethylphosphate (DEP), Dimethylphosphate (DMP), Monoethyl Phthalate (MEP), N-acetyl phenyl cysteine (NAP), Phenylglyoxylic Acid (PGO), Thiodigly

Acid (TDG), Tiglyglycine (TG)Hormones Comprehensive Panel

- 3 weeks Estradiol, Progesterone, Testosterone, DHEA, am/noon/evening/pm Cortisol

Hormones Comprehensive Plus Panel- 3 weeks

Estrone, Estradiol, Estriol, Progesterone, Testosterone, DHEA, am/noon/evening/pm Cortisol

Hormone Short Comprehensive Panel - 3 weeks

Estradiol, Progesterone, Testosterone, DHEA, am /pm Cortisol

gE Allergy Advanced Combined Test93 / 69)- 2 weeks

See IgE Food Allergy Advanced Test (93) and IgE Inhalant Allergy Advanced Test (69) for test descriptions.

gE Food Allergy Essentials Test (12) - 2 weeks Almond, Beef, Chicken, Corn, Egg White, Milk, Orange, Peanut, Shrimp, Soybean, Tomato, Wheat

gE Food Allergy Basic Test (25) - 2 weeks

Almond, Apple, Barley, Bean (White), Beef, Chicken, Chocolate, Corn, Egg (Whole), Garlic, Milk, Oat, Onion, Orange, Peanut, Pork, Potato, Rice, Shellfi

(Cod, Shrimp, Mussel, Tuna, Salmon), Soybean, Tomato, Tuna, Vegetable Mix (Green Bean, White Bean, Carrot, Potato), Wheat, Yeast (Bakers)

gE Food Allergy AdvancedTest (93)

- 2 weeks

Almond, Apple, Apricot, Asparagus, Avocado, Banana, Barley, Beef, Beet, Blueberry, Broccoli, Buckwheat, Cabbage, Cane Sugar, Carrot, Casein, CashCelery, Cheese, Chicken, Coconut, Cod Fish, Cocoa, Coffee, Corn, Crab, Cranberry, Eggplant, Egg White, Egg Yolk, Flax, Garbanzo Bean, Garlic, GluteMilk Cheese, Grape, Grapefruit, Green Bean, Green Pepper, Halibut, Hazelnut, Honey, Kidney Bean, Lamb, Lemon, Lentil, Lettuce, Lima Bean, Lobster, MMilk, Millet, Mushroom, Oat, Onion, Orange, Papaya, Pea, Peach, Peanut, Pear, Pecan, Pineapple, Pinto Bean, Pistachio, Plum, Pork, Potato, Pumpkin, Raisin, Rice, Rye, Salmon, Sardine, Sesame, Shrimp, Soybean, Spinach, Strawberry, Sunflower, Sweet Potato, Tomato, Turkey, Tuna, Walnut, WatermeWheat, Whey, Yogurt, Yeast (Bakers), Yeast (Brewers), Zucchini

gE Inhalant Allergy Basic Test (36) - 2 weeks

Alder (Speckled), Alternaria, Ash (White), Aspergillus, Beech (American), Bermuda Grass, Birch (Common Silver), Box Elder (Maple), Burning Bush, CatCladosporium, Cocklebur, Cockroach, Cottonwood Tree, Dog, Elm (White), Hickory (White), House Dust, Lamb’s Quarters, Marsh Elder (Rough), MeadowFescue, Mite (D. Farinae), Mugwort, Nettle, Oak (White), Orchard Grass/Cocksfoot, Penicillium, Pigweed, Pine Ponderosa, Plantain (English), Privet, Rag(Short), Rye (Perennial), Sheep Sorrel, Sycamore (American), Timothy Grass

gE Inhalant Allergy A dvancedTest (69)

- 2 weeks

Acacia, Alder (Smooth), Alternaria, Amoxicillin, Ash (White), Aspergillus, Bahia Grass, Bermuda Grass, Bluegrass (Kentucky), Box Elder (Maple), Brome GrassCandida, Cat, Cedar (Mountain), Cladosporium, Cocklebur, Cockroach, Corn (Cultivated), Cottonwood Tree, Cypress (Bald), Dockweed (Yellow), Dog, Elm (Amand Fall Blooming), Ferret, Fescue (Meadow), Gerbil, Goldenrod, Hickory (White), House Dust, Iodine Bush, Johnson Grass, Lamb’s Quarters, Maple (Red), MElder (Rough), Mexican Tea, Mite (D. Farinae), Mouse, Mulberry (Red and White), Nettle, Oak (Live, White, and Red), Oats, (Cultivated), Oat Grass Tall, PecanPenicillium, Pigweed (Spiny and Rough), Plantain (English), Poplar (White), Privet, Rabbit, Ragweed (Giant and Short), Rye (Cultivated), Rye Grass (PerenniaCedar, Salt Grass, Sheep Sorrel, Sweet Gum, Sycamore, Timothy Grass, Tree of Heaven, Walnut (Black), Western Water Hemp, Wheat (Cultivated), Willow (B


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Revised 07

gG Food Allergy Test w/ Candida (94)- 2 weeks

Almond, Apple, Apricot, Asparagus, Avocado, Baker’s Yeast (Saccharomyces cerevisiae), Banana, Barley, Beef, Beet, Blueberry, Brewer’s Yeast(Saccharomyces cerevisiae),Broccoli, Buckwheat, Cabbage, Candida albicans, Cane Sugar, Carrot, Cashews, Casein, Celery, Cheese, Chicken, CocoaCod fish, Coffee, Corn, Crab, Cranberry, Eggplant, Egg White, Egg Yolk, Flax, Garbanzo Beans, Garlic, Gliadin, Goat’s Milk Cheese, Grape, Grapefruit, GBean, Green Pepper, Halibut, Hazelnut, Honey, Kidney Bean, Lamb, Lemon, Lentil, Lettuce, Lima bean, Lobster, Milk, Millet, Mozzarella Cheese, MushroOnion, Orange, Papaya, Pea, Peach, Peanut, Pear, Pecan, Pineapple, Pinto Bean, Pistachio, Plum (Prune), Pork, Potato, Pumpkin, Radish, Rice, Rye, Sardine, Sesame, Shrimp, Sorghum, Soybean, Spinach, Strawberry, Sunflower, Sweet Potato, Tomato, Tuna, Turkey, Wheat Gluten, Walnut, WatermeloWheat, Whey, Yogurt

gG Food Allergy Test w/ Candida + IgEood Allergy Essentials Test- 2 weeks

See IgG Food Allergy Test w/ Candida and IgE Food Allergy Essentials Test for test descriptions.

gG Asian Food Allergy Testw/ Candida (94)

- 2 weeks

Abalone, Adzuki Bean, Almond, Apple, Bamboo Shoot, Banana, Barley, Beef, Black Pepper, Bonito, Buckwheat, Burdock (Gobo), Cabbage, Candida albCarrot, Casein, Cauliflower, Celery, Cheese, Cherry, Chestnut, Chicken, Clam, Cocoa, Coconut, Coffee, Corn, Crab, Cucumber, Curry Powder, Duck, EgEggplant, Garlic, Ginger, Grape, Green Bean, Green Pepper, Green Tea, Honey, Jack Mackerel, Kiwi, Kombu (Kelp), Lamb, Laver (Nori), Lettuce, Lotus Mackerel, Mango, Melon, Milk, Miso, Mushroom-Enoki, Mushroom-Shiitake, Mustard, Oat, Olive, Onion, Oolong Tea, Orange, Oyster, Pacific Saury, PeaPeanut, Pear, Pineapple, Pistachio, Pork, Potato, Pumpkin, Radish-Daikon, Red Pepper, Rice, Rye, Salmon, Sardine, Seaweed (Wakame), Sesame, ShSoybean, Spinach, Squid, Strawberry, Sunflower, Sweet Potato, Tomato, Tuna, Vanilla Bean, Wheat, Wheat Gluten, Whey, Yeast (Brewer’s), Yogurt

mmune Deficiency Profil e - 3 weeks

Immunoglobulins IgA, IgM, IgE, IgG and IgG Subclasses 1, 2, 3 and 4, and Zinc

Kryptopyrro le Test - 3 weeks Kryptopyrrole

Metals Fecal Test (13) - 3 weeks

Toxic: Antimony, Arsenic, Beryllium, Bismuth, Cadmium, Copper, Lead, Mercury, Nickel, Platinum, Thallium, Tungsten, Uranium

Metals Hair Test (39) - 3 weeks

Nutritional: Calcium, Magnesium, Sodium, Potassium, Copper, Zinc, Manganese, Chromium, Vanadium, Molybdenum, Boron, Iodine, Lithium, Phosphorus, SStrontium, Sulfur, Barium, Cobalt, Iron, Germanium, Rubidium, Zirconium. Ratios: Calcium/Magnesium, Sodium/Potassium, Zinc/Copper, Zinc/Cadmium,Calcium/Phosphorus Toxic: Aluminum, Antimony, Arsenic, Beryllium, Bismuth, Cadmium, Lead, Mercury, Platinum, Thallium, Thorium, Uranium, Nickel, SilveTitanium

Metals Red Blood Cell Test (18) - 3 weeks

Nutritional: Boron, Chromium, Calcium, Copper, Iron, Magnesium, Manganese, Molybdenum, Phosphorus, Potassium, Selenium, Vanadium, Zinc Toxi Arsenic, Cadmium, Lead, Mercury, Thallium

Metals Urine Test (37) - 3 weeks

Nutritional: Boron, Calcium, Chromium, Cobalt, Copper, Iron, Magnesium, Manganese, Molybdenum, Phosphorus, Potassium, Selenium, Sodium, StronSulfur, Vanadium, and Zinc Toxic: Aluminum, Antimony, Arsenic, Barium, Beryllium, Bismuth, Cadmium, Cesium, Gadolinium, Lead, Mercury, Nickel, PaPlatinum, Tellurium, Thallium, Thorium, Tin, Tungsten, Uranium

Metals Whole Blood Test (20) - 3 weeks

Nutritional: Calcium, Copper, Lithium, Magnesium, Manganese, Molybdenum, Selenium, Strontium, Zinc Toxic: Arsenic, Barium, Cadmium, Cobalt, LeMercury, Nickel, Platinum, Silver, Thallium, Uranium

Microbial Organic Acids Test (MOAT) (21) - 2 weeks

Citramalic, 5-Hydroxymethyl-2-Furoic, 3-Oxoglutaric, Furan-2,5-Dicarboxylic, Furancarbonylglycine, Tartaric, Arabinose, Carboxycitric, Tricarballylic, 2-Hydroxyphenylacetic, 4-Hydroxyphenylacetic, 4-Hydroxybenzoic, 4-Hydroxyhippuric, HPHPA (Clostridia marker), 4-Cresol, DHPPA (beneficial bacteria), 3-Indoleacetic, 3-Hydroxy-3-methylglutaric, 2-Hydroxyhippuric, Creatinine

Microbial Organic A cids Test + Yeast Culture w/ Sensitivity Test Combo

- 3 weeks See Microbial Organic Acids Test and Yeast Culture w/ Sensitivity Test for test descriptions.

Organic Acids Test (OAT) (74) - 2 weeks

Citramalic, 5-Hydroxymethyl-2-furoic, 3-Oxoglutaric, Furan-2,5-dicarboxylic, Furancarbonylglycine, Tartaric, Arabinose, Carboxycitric, Tricarballylic, 2-HydroxyphenylaHydroxyphenylacetic, 4-Hydroxybenzoic, 4-Hydroxyhippuric, Hippuric, 3-Indoleacetic, Succinic, HPHPA (Clostridia marker), 4-Cresol (C. difficile), DHPPA (beneficial Glyceric, Glycolic, Oxalic, Lactic, Pyruvic, 2-Hydroxybutyric, Fumaric, Malic, 2-Oxoglutaric, Aconitic, Citric, Homovanillic Acid (HVA), Vanillmandelic Acid (VMA), HVA/VRatio, 5-Hydroxyindoleacetic (5-HIAA), Quinolinic, Kynurenic, Quinolinic / 5-HIAA Ratio, Uracil, Thymine, 3-Hydroxybutyric, Acetoacetic, 4-Hydroxybutyric, EthylmalonMethylsuccinic, Adipic, Suberic, Sebacic, Methylmalonic (Vitamin B12), Pyridoxic (Vitamin B6), Pantothenic (Vitamin B5), Glutaric (Vitamin B2-Riboflavin), Ascorbic (V

3-Hydroxy-3-methylglutaric (Vitamin Q10-CoQ10), N-Acetylcysteine (Glutathione precursor and chelating agent), Methylcitric (Vitamin H-Biotin), Pyroglutamic, Orotic,Hydroxyhippuric, 2-Hydroxyisovaleric, 2-Oxoisovaleric, 3-Methyl-2-oxovaleric, 2-Hydroxyisocaproic, 2-Oxoisocaproic, 2-Oxo-4-methiolbutyric, Mandelic, PhenyllacticPhenylpyruvic, Homogentisic, 4-Hydroxyphenyllactic, N-Acetylaspartic, Malonic, 3-Methylglutaric, 3-Hydroxyglutaric, 3-Methylglutaconic, Phosphoric, Creatinine

Organic Acids Test + Amino Acid s Urine Test Combo

- 3 weeks See Organic Acids Test and Amino Acids Urine Test for test descriptions.

Organic Acids Test + IgG Food AllergyTest w/ Candida Combo

- 3 weeks

See Organic Acids Test and IgG Food Allergy Test w/ Candida for test descriptions.

Organic Acids Test + Yeast Culture w/Sensitivit y Test Combo

- 3 weeks See Organic Acids Test and Yeast Culture w/ Sensitivity Test for test descriptions.

Phospholipase A2 Activi ty Test- 2 weeks

Phospholipase A2 Activity

Porphyrins Profile (2 - 3 weeks) Coproporphyrin I and III (CP), Heptacarboxy (7-CP), Hexacarboxy (6-CP), Pentacarboxy (5-CP), Precoproporphyrin (PreCP), Uroporphyrins (UP)

Prealbumin Test (1 - 3 weeks) Prealbumin

Streptococcus Antibodies Profile - 3 weeks

DNase antibodies in serum (ADB); Antistreptolysin O titer (ASO)

Uric Acid Test (1 - 3 weeks) Uric Acid, Creatinine

Vitamin D Test: SerumVitamin D Test: Dried Blood Spot (DBS) Serum: 2 - 3 weeks DBS: 3 - 4 weeks

25-Hydroxyvitamin D2 (ergocalciferol), 25-Hydroxyvitamin D3 (cholecalciferol)

Yeast Culture w/ Sensitivity Test - 3 weeks

Yeast (Mycology) c ulture: 48 possible yeast and fungal species; Yeast (microscopy - visible presence of yeast cells); Yeast sensitivity to: Berberine, Acid, Uva Ursi , Tannic Acid, Oregano, Undecylenic Acid, Citrus Seed Extract, Nystatin, Fluconazole, Itraconazole, Ketoconazole

inc Test (2 - 3 weeks) Zinc

PLEASE NOTE: *SST tubes are not sent in international test kits - Navy blue top tubes wi th (no additive) are provided in international test kits .


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Turn-Around-Times and Specimen Collection

Turn-Around-Times

and SpecimenCollection

Turn-Around-Times and Specimen Collection


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T y p e o f T u b e / V i a l

T y p e o f S p e c i m e n

A b s o l u t e

M i n i m u m

R e q u e s t e d

A m o u n t

T u r n A r o u n d T i m e

T u r n A r o u n d T i m e s & S p e c i m e n R e q u i r e m e n t s

M i c

r o b i a l O r g a n i c A c i d s T e s t ( M O A T ) ( 2 0 )

7 0 m L U r i n e C o l l e c t i o n C u p

F i r s t M o r n i n g U r i n e

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F r e e z e

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great plains laboratory clinician manual

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