Gut Editorial Committee

J J MISIEWICZ(Editor)

D L WINGATE(Book Review Editor)

A ALLEND J ALLISONE L BLAIR

S R BLOOMR M CASER COCKELP B COTTONA G COXG P CREANJ FIELDINGR C HEADINGI D HILL

H J F HODGSOND P JEWELLA G JOHNSONR M KIRKA S McNEISHT J PETERSA B PRICEN READI TAYLOR

G T WILLIAMSROGER WILLIAMSK G WORMSLEY

EDITORBritith Medical Journal

SHIRLEY McGEALEY(Technical Editor)

Gut publishes original papers and reviews concerned withpractice and research in the field of gastroenterology. Thefield is that of alimentary, hepatic, or pancreatic disease,and papers may cover the medical, surgical, radiological,or historical aspects. They may also deal with the basicsciences concerned with the alimentary tract, includingexperimental work. A case report will be accepted only if itdeals with a clinical problem which has been studied indetail and the resulting data provide material for furtherresearch. Letters dealing with matters arising from articlespublished in Gut, or with topics of general professionalinterest are encouraged, but the correspondence columnshould not be used for publication of original data.

COMMUNICATIONS Two copies of papers and figuresshould be addressed to the Editor, Gut, BMA House,Tavistock Square, London WC1H 9JR. Papers areaccepted only on the written understanding, signed by allauthors, that they are not published elsewhere withoutprevious sanction of the Editorial Committee, and that allauthors agree to publication in Gut. Manuscripts shouldfollow the Vancouver conventions (see Br Med J 1979; 1:532-5. Gut 1979; 20: 651-2).They should be in double-spaced typewriting on one side of the paper only. On thepaper the name of the author should appear with initials(or distinguishing first name) only, and the name andaddress of the hospital or laboratory where the work wasperformed. A short summary should be provided at thebeginning of the paper.

ACKNOWLEDGEMENT OF MANUSCRIPTS Manuscripts willnot be acknowledged unless a stamped addressed postcardor international reply coupon is enclosed.

ILLUSTRATIONS Photographs Unmounted photographson glossy paper should be provided. Diagrams These willusually be reduced to 2i in wide. Lettering should be ineither Letraset or stencil, and care should be taken thatlettering and symbols are of comparable size. Illustrationsshould not be inserted in the text, they should be markedon the back with Figure numbers, title of paper, and nameof author. All photographs, graphs, and diagrams shouldbe referred to as Figures and should be numberedconsecutively in the text in Arabic numerals. The legendsfor illustrations should be typed on a separate sheet.Tables Tables should be numbered consecutively in thetext in Arabic numerals and each typed on a separatesheet.

ETHICS Ethical considerations will be taken into accountin the assessment of papers (see the Medical ResearchCouncil's publications on the ethics of human experi-mentation, and the World Medical Association's code ofethics, known as the Declaration of Helsinki (see Br Med J1964; 2:177)).

SI UNITS All measurements except blood pressure areexpressed in SI units. In the text they should be followed

by traditional units in parentheses. In tables and illustra-tions value are given in SI units, but a conversion factormust be supplied. For general guidance on the Internation-al System of Units and some useful conversion factors, seeThe SIfor the Health Professions (WHO, 1977). NB: Suchconversion is the responsibility of the author.

REFERENCES These follow the Vancouver system - thatis, references numbered consecutively in the text and listednumerically with titles abbreviated in the style of IndexMedicus, Standard journal article - (list all authors whensix or less; when seven or more, list first three and add etal): James A, Joyce B, Harvey T. Effect of long-termcimetidine. Gut 1979; 20: 123-4. NB: Accurate punctuationis essential.

CORRECTIONS other than printers' errors may be chargedto the author.

REPRINTS Twenty-five reprints will be supplied free ofcharge. Further reprints will be available on payment ofthe necessary costs; the number of reprints required shouldbe sent to the Publishing Manager on the form providedwith the proof.

NOTICE TO ADVERTISERS Application for advertisementspace and for rates should be addressed to the Advertise-ment Manager, Gut, BMA House, Tavistock Square,London WC1H 9JR.

NOTICE TO SUBSCRIBERS Gut is published monthly. Theannual subscription rates are available on request to theSubscription Manager, Gut, BMA House, TavistockSquare, London WC1H 9JR. Orders can also be placedwith any leading subscription agent or bookseller. (For theconvenience of readers in the USA subscription orders,with or without payment, can also be sent to: BritishMedical Journal, Box 560B, Kennebunkport, Maine04046. All enquiries, however, must be addressed to thePublisher in London.) All enquiries regarding Air Mailrates and single copies already published should beaddressed to the Publisher in London.

COPYRIGHT © 1985 Gut. This publication is copyrightunder the Berne Convention and the International Copy-right Convention. All rights reserved. Apart from anyrelaxations permitted under national copyright laws, nopart of the publication may be reproduced, stored in aretrieval system or transmitted in any form or by anymeans without the prior permission of the copyrightowners. Permission is not, however, required to copyabstracts of papers or articles on condition that a fullreference to the source is shown. Multiple copying of thecontents of the publication without permission is alwaysillegal.

ISSN 0017-5749

1390 Books

good example of the genre. In part this reflects theoften serious lack of knowledge about mineralabsorption. More importantly, it is because, ingeneral, authors have not been prepared to reviewtheir subject, merely to catalogue progress. It is alsobecause the editors seem to have done little editing.Thus, for example, each chapter includes a some-times laborious description of the techniques formeasuring absorption. As in general, these do notdiffer between minerals, it might have been moreappropriate to include an opening chapter on thistopic rather than the one offered by the editors on'physiological and pathological mechanisms in min-eral absorption' which says very little. It is perhapsnot surprising that the lengthy chapter on zinc iswritten by one of the editors. Finally, the publishersare not blameless. From the references it is clearthat most chapters were written in 1982. The bookwas sent to Gut for review in January 1985. Whydoes it take two years to publish a book?

MAYNARD CASE

Integrated clinical science - gastroenterology By PF Jones, P W Brunt, and N A G Mowat. (Pp 365;illustrated; £12.50.) London: Heinemann, 1985.This has to be the best illustrated short text book ofgastroenterology. If you need to make teachingslides, the hundreds of line drawings are absolutelyideal. The book is a very reasonable price for its 365pages, but with so many illustrations the text isnecessarily short. It is written for the 'interested'final year student, or as core reading for themembership or fellowship candidate. I think thebook succeeds, and it can be strongly recommendedfor these 'non-gastroenterologists'.

R E POUNDER

Coloproctology and the pelvic floor Edited by MHenry and M Swash. (Pp 407; illustrated; price notstated.) London: Butterworths, 1985.Although the title sounds rather like that of aromantic novel and is literally enigmatic, this is atimely book. The important parts of the book arethe sections dealing with the methods of assessmentof the patients presenting with pelvic floor abnorma-lities; these sections, written by the two editors, areparticularly valuable.The general standard of printing and reproduction

of the illustrations is a weak point of the book. Manyof the illustrations have been borrowed from otherarticles and textbooks written by the chapter au-thors. Some of these have reproduced well but manyof the halftone drawings look indistinct and cheap.The radiograph reproduction and even the blackand white histological reproductions of musclefibres look good but the overall appearance of the

work suffers from the lack of a 'housestyle' of theillustrations. It is difficult to believe that anyoneasked to write a chapter on the anatomy of anussphincters and pelvic floor could do so with the useof only one crude figure and 115 references; 30figures and 30 references would have been a betterproportion. One has the impression that the produc-tion of the book was somewhat hurried to meet thedeadline of the 150th anniversary celebrations of StMark's Hospital. With more time and attention tographic detail this book might well have become aclassic. I expect that it will sell well particularly atthe meeting.

J ALEXANDER-WILLIAMS

Case presentations in gastrointestinal diseaseEdited by W D W Rees, S Hughes, J L Shaffer, andG R Barclay. (Pp 201; illustrated; £6.95.) London:Butterworths, 1985.The book is in two parts: 60 case presentations withquestions and answers, followed by eight shortreview articles.The case presentations are a great success. They

cover most gastrointestinal problems and are writtenin an interesting, light style. A few questions areasked the 'examiner' with model answers providedlater in the book. It is a pity that these answers arenot shuffled, as it is almost impossible not to cheat.Perhaps the reader should start at case 60 and workbackwards. The answers allow the authors to discussthe up to date differential diagnosis, managementand treatment of each condition.The eight review articles seem out of place - they

only discuss a few aspects of gastroenterology whichcould have been covered by another 20 casepresentations in the same space.

Gastroenterologists will find the book quite un-like outpatients: 59 organic problems and only onepatient with an irritable bowel! A pleasure to read,which may help their teaching.

R E POUNDER

Books receivedRadiology cumulative index 1978-1982 Edited byWilliam R Eyler. (Pp. 688; not illustrated; no pricestated.) Illinois: Radiological Society of NorthAmerica, 1983.

Vagotomy in modern surgical practice Edited byJ H Baron, J Alexander-Williams, M Allgower, CMuller, and J Spencer. (Pp. 378; illustrated;£38.00.) Sevenoaks, Kent: Butterworth Group,1982.

Volume 26 General IndexAADLAND, E. See KITIANG, E, AADLAND, E, et al.Abdominal tuberculosis (Leading article), 1275

in urban Britain (experience of W. London districtgeneral hospital, 1973-83), 1296

ABRAVANEL, G M. See MARTY, J F, VERNAY, M Y, et al.Abscess of liver, amoebic, cholestasis in, 140Acetaldehyde as initiator of hepatocellular damage in acute

alcoholic liver disease, 1065Acetate absorption and metabolism in rabbit hindgut, 562ACHESON, D W K. See BRAGANZA, J M, and ACHESON, D W K

Acid exposure, endogenous, oesophageal motor events in healthysubjects and in oesophagitis during, 336

ACTH and gastrin, neuroendocrine islet cell tumour producing, incalcifying chronic pancreatitis (Case report), 426

Adenine arabinoside 5'-monophosphate in chronic hepatitis Bvirus infection (Clinical trial), 745

Adenocarcinoma, colonic, elution of cytomegalovirus antibodiesfrom, 1053

ADEYEMI, E 0, NEUMANN, S, CHADWICK, V S, HODGSON, H J F, and

PEPYS, M B: Circulating human leucocyte elastase in patients withinflammatory bowel disease, 1306

Adrenergic effects on epidermal growth factor secretion fromBrunner's glands, 920

Adrenocorticotrophic hormone. See ACTHADRIAN, T E. See PRESTON, D M, ADRIAN, T E, et al.

See SAVAGE, A P, GORNACZ, G E, et al.See WOOD, S M, KRAENZLIN, M E, et al.

Age, normal gastro-oesophageal reflux influenced by?, 799AHONEN, J. See PAIMELA, H, HARKONEN, M, et a!.

AIDS, diarrhoea and malabsorption in, 4 cases showing frequencyof unusual protozoan infestations, 179

, granulomatous involvement of liver in, 1220AINGE, G. See POYNTER, D, PICK, C R, et al.AINLEY, C C. See LEDGER, J E, WATSON, G j, et al.AIREY, M. See MAYER, A D, AIREY, M, et al.AKKERMANS, L M A. See SMOUT, A J P M, BOGAARD, J w, et al.AL-AGHBAR, M N A, NEUBERGER, J, WILLIAMS, R, and EDDLESTON,A L W F: Mononuclear cell complement blockade in primarybiliary cirrhosis, 20

Alcohol, absolute, endoscopic sclerotherapy using, 120and parenteral heroin abuse in young adults, association of

hepatic cirrhosis with (Leading article), 8Alcoholic cirrhosis, ascitic fluid pH in, diagnosis of spontaneous

bacterial peritonitis from, reevaluation of, 332, decompensated, renal function enhancement with

ornipressin in (Case report), 1385-liver disease, acute, acetaldehyde as initiator of hepatocellulardamage in, 1065

pancreatitis, chronic, comparison of oral (PABA) pancreaticfunction test, secretin-pancreozymin test and ERCP in, 1257

, development of, diet and drinking habits in relation to,882

ALEXANDER-WILLIAMS, J. See FABRICIUS, P J, GYDE, S N, et al.Alimentary tract. See Gastrointestinal tractAL-JANABI, M N. See READ, N W, AL-JANABI, M N, et al.Alkaloid exposure, toxic, quantification in adults with herbal tea

induced hepatic veno-occlusive disease (Case reports), 101ALLAN, A, BRISTOL, J B, and WILLIAMSON, R C N: Crypt cell

production rate in ulcerative proctocolitis: differential incre-ments in remission and relapse, 999

ALLAN, R N. See FABRICIUS, P J, GYDE, S N, et al.See RHODES, J M, GALLIMORE, R, et al.See RHODES, J M, MARSHALL, T, et al.

ALLEN-MERSH, T G: What is the significance of pancreatic ductalmucinous hyperplasia?, 825

ALLISON, M C, RENFREW, C C, WEBB, W J S, CHAPPELL, M E, and

POUNDER, R E: Neuroendocrine islet cell tumour producinggastrin and ACTH in a patient with calcifying chronic pancreati-tis (Case report), 426

AL-MUKHTAR, M Y T. See MIAZZA, B M, AL-MUKHTAR, M Y T, et al.See SAGOR, G R, GHATEI, M A, et al.

ALPEROVITCH, A. See SAINT-MARC GIRARDIN, M-F, LE MINOR, M, et al.Alpha-heavy chain disease, non-secretory, in plasma cell infiltra-

tion of small bowel, no evidence for, 928AMBINDER, E P. See COHEN, L B, AMBINDER, E P, et al.AMERIGO, J. See EARLAM, R J, AMERIGO, J, et al.Amino acids, free, whole protein and hydrolysed protein, relative

nutritional value of, 6945-Aminosalicylic acid enemas in ulcerative colitis, topical adminis-

tration and rectal absorption and excretion, 400Anal sphincter, external, musculature, and puborectalis muscle,

innervation to, in anorectal incontinence and rectal prolapse, 470ANAND, B S. See BHALLA, S, vIJ, J C, et al.

See SARIN, S K, SACHDEVA, G K, et al.- See VIJ, J C, ANAND, B S, et al.

ANDERSEN, B N, LARSEN, N-E, RUNE, S J, and WORNING, H: Develop-ment of cimetidine resistance in the Zollinger-Ellison syndrome(Case report), 1263

ANDERSON, K C. See WAITERS, D A K, SMITH, A N, et al.ANDERSON, M G, and MURRAY-LYON, I M: Natural history of theHBsAg carrier (Progress report), 848

Aneurysm of hepatic artery, diagnosis and management of, CATscanning in (Case report), 752

ANGELELI, A Y O. See RODRIGUES, M A M, DE CAMARGO, J L v, et al.ANNIBALE, B. See KOHN, A, ANNIBALE, B, et al.Anorectal and gastrointestinal disorders in homosexual men

(Leading article), 869incontinence and rectal prolapse, innervation to puborectalis

and external anal sphincter muscles in, 470ANSALDI, N. See FARCI, P, BARBERA, C, et al.ANTHONY, P P. See FREEMAN, K, ANTHONY, P P, et al.Antibiotics, non-absorbable, plus elemental diet in active Crohn's

disease, comparative trial with prednisolone, 994Antibodies, cytomegalovirus, elution from adenocarcinoma of

colon, 1053monoclonal. See Monoclonal antibodiesto gliadin detected by immunofluorescence and micro-ELISA

method, value as markers of active childhood and adult coeliacdisease, 667

Antibody, monoclonal. See Monoclonal antibodyAntibody-mediated hepatocyte injury in methyl dopa induced

hepatotoxicity, 1233Antidiarrhoeal agent, new. See NufenoxoleAntigen, hepatitis B surface. See Hepatitis B surface antigen

, oncofetal, pancreatic, enzyme immunoassay of, as marker ofpancreatic cancer, 450

Antigens, HLA-DR, not associated with susceptibility to primarybiliary cirrhosis, 625

Anti-inflammatory drugs, non-steroidal, and peptic ulcer perfora-tion, 359; (Letters), 981

Antrum, oesophagus and duodenum, histological appearances andcorrelation with symptoms in duodenal ulcer, 95

Appendix, gut associated lymphoid tissue in, morphological andimmunocytochemical study of, 672

ARMSTRONG, C P, TAYLOR, T v, and TORRANCE, H B: Pressure, volumeand the pancreas, 615

ARNDT, R. See SCHMIEGEL, W H, KREIKER, C, et al.ARTHUR, M J P, TANNER, A R, PATEL, C, WRIGHT, R, RENWICK, A G, and

GEORGE, C F: Pharmacology of propranolol in patients withcirrhosis and portal hypertension, 14

See also HILLER, K, SMITH, C L, et al.ARVIDSSON, S, FALT, K, and HAGLUND, U: Gastric mucosal damage in

sepsis-effects of pretreatment with a synthetic prostaglandin E,analogue, 1025

Ascites and cirrhosis, renal function impairment induced byposture change in, 629

1391

General index

chylous, and intestinal lymphangiectasia in 'yellow-nail'syndrome (Case report), 1266

, refractory, peritoneovenous shunt surgery for, morbidity andmortality after, 1070

Ascitic fluid pH in alcoholic cirrhosis for diagnosis of spontaneousbacterial peritonitis, reevaluation of, 332

Aspirin and taurocholate, gastric mucosal damage in rat inducedby, effect of cimetidine and omeprazole, 770

AURICCHIO, S. See PIGNATA, C, TRONCONE, R, et al.

Autonomic regulation of postprandial plasma somatostatin, gas-

trin, and insulin, 683AXON, A T R. See DICKINSON, R J, O'CONNOR, H J, et al.

- See HAMILTON, 1, COBDEN, I, et al.See WINSTANLEY, P A, ELLIS W R, et al.

AYLOTT, A. See DANESH, B J Z, BURKE, M, et al.AZIZ, L A. See BATE, C M, and AZIZ, L A

BABB, R R, and 'I'ROLLOPE, M L: Acute fulminating amoebic colitis:survival after total colectomy (Case report), 301

Bacterial peritonitis, spontaneous (Leading article), 325diagnosis from ascitic fluid pH in alcoholic

cirrhosis, reevaluation of, 332BAILLOD, R. See JEFFREY, G, KIBBLER, C C, et al.BALDI F, FERRARINI, F, BALESTRA, R, BORIONI, D, LONGANESI A,

MIGLIOLI, M, and BARBARA, L: Oesophageal motor events at theoccurrence of acid reflux and during endogenous acid exposure

in healthy subjects and in patients with oesophagitis, 336BALESTRA, R. See BALDI, F, FERRARINI, F, et al.Balloon expulsion from rectum in constipation of different types,

1049BALSANO, F. See BARNABA, V, IAMBURRINI, E, et al.

BANK, S, ZIMMERMAN, H, SMOLOW, c, and KRANZ, V: Prevention ofduodenal ulcers in the rat using a combination of ranitidine andsucralphate in subtherapeutic doses, 603

BARALDINI, M. See BERNARDI, M, SANTINI, C, et al.

BARATZ, M. See BAR-MEIR, S, HALPERN, z, et al.BARBARA, L. See BALDI, F, FERRARINI, F, et al.BARBERA, C. See FARCI, P, BARBERA, C, et al.BARBIERI, C. See CALDARA, R, BARBIERI, C, et al.

BAR-MEIR, S, HALPERN, Z, GUTMAN, M, SHPIRER, Z, BARATZ, M, and

BASS, D: Effect of (+)-cyanidanol-3 on chronic active hepatitis: a

double blind controlled trial (Clinical trial), 975BARNABA, V, I'AMBURRINI, E, LAGHI, V, CAUDA, R, LEVRERO, M,

RUOCCO, G, ORTONA, L, and BALSANO, F: Peripheral bloodmononuclear cells and regulatory T cells in acute viral hepatitis,739

BARNES, P R H, and LENNARD-JONES, J E: Balloon expulsion from therectum in constipation of different types, 1049

BARON, J H. See THOMPSON, J N, BARR, J A, et al.BARONI, S. See PARENIE, F, LAZZARONI, M, et al.

BARR, J A. See THOMPSON, J N, BARR, J A, et al.BARR, L C, BOOTH, J, FILIPE, M I, and LAWSON, J O N: Clinical

evaluation of the histochemical diagnosis of Hirschsprung'sdisease, 393

BARRY, R E, and MCGIVAN, J D: Acetaldehyde alone may initiatehepatocellular damage in acute alcoholic liver disease, 1065

BARTER, S J. See JEFFREE, M A, BARTER, S J, et al.BASILISCO, G, BOZZANI, A, CAMBONI, G, RECCHIA, M, QUATRINI, M,

CONTE, D, PENAGINI, R, and BIANCHI, P A: Effect of loperamide andnaloxone on mouth-to-caecum transit time evaluated by lactu-lose hydrogen breath test, 700

See also QUAIRINI, M, BASILISCO, G, et al.BASRAN, G S. See PALMER, K R, PATIL, D H, et al.BASS, D. See BAR-MEIR, S, HALPERN, z, et al.BASSENDINE, M F, COLLINS, J D, STEPHENSON, J, SAUNDERS, P, and

JAMES, 0 F W: Platelet associated immunoglobulins in primarybiliary cirrhosis: a cause of thrombocytopenia?, 1074

DEWAR, P j, and JAMES, 0 F w: HLA-DR antigens.in primarybiliary cirrhosis: lack of association. 625

BATE, c M, and AZIZ, L A: Electrohydrothermoprobe-a simplealternative to laser therapy in the management of acutegastrointestinal haemorrhage, 477

BATES, T E. See READ, N W, AL-JANABI, M N, et al.BATIEN, J C. See ZENTLER-MUNRO, P L, FINE, D R, et al.

Battery, miniature, endoscopic retrieval of (Letter), 215BAX, R. See VAN SPREEUWEL, J P, DUURSMA, G c, et al.

BAXTER, J N, GRIME, J S, CRITCHLEY, M, and SHIELDS, R: Relationshipbetween gastric emptying of solids and gall bladder emptying innormal subjects, 342

BAZZOCCHI, G. See CAMPIERI, M, LANFRANCHI, G A, et al.

BEALE, P J. See HULL, D H, and BEALE, P J

BEAITY D W. See GILINSKY, N H, MEE, A s, et al.BECKE-Il-, G J, CHAPMAN, B J, DYSON, E H, and HAYES, J D: Plasma

glutathione S-transferase mcasurements aftcr paracetamol over-

dose: evidence for early hepatocellular damage, 26BEE1'HAM, R. See MORIARTY K J, KELLY, M J, et al.BEGLINGER, C, KOHLER, E, WHITEHOUSE, I, and GYR, K: Secretin and

pancreatic enzyme secretion (Letter), 320BELLENTANI, S, GRISENDI, A, and MANENTI, F: Serum PABA test in

chronic pancreatitis (Letter), 537BELLUZZI, A. See CAMPIERI. M, LANFRANCHI, A, et al.

BENHAMOU, J P. See BERCOFF, E, BERNUAU, J, et al.

BENNE1r, M K. See HARPER, P H, LEE, E C G, et al.BENSON, L H. See FARAH, D A, CALDER, I, et al.

See MACKENZIE, J F, CALDER, I, et al.BEPPU, T. See IAKIKAWA, H, BEPPU, 'i, et al.

BERCOFF, E, BERNUAU, J, DEGOTT, C, KALIS, B, LEMAIRE, A, TILLY, H,

RUEFF, B, and BENHAMOU, i P: Ketoconazole-induced fulminanthepatitis (Case reports), 636

BERGHOUSE, L. See MCINTYRE, P B, MACRAE, F A, et al.

BERNAL, A L. See GIBSON, P R, HERMANOWICZ, A, et al.

BERNARDI, M, SAN'I'INI, C, 'I'REVISANI, F, BARALDINI, M, LIGABUE, A,

and GASBARRINI, G: Renal function impairment induced bychange in posture in patients with cirrhosis and ascites, 629

BERNIER, J J. See JIAN, R, DUCROT, F, et al.BERNSTEIN, L. See WILSON, J S, BERNSTEIN, L, et al.

BERNUAU, J. See BERCOFF, E, BERNUAU, J, et al.

Beta, adrenoreceptor blocker, selective. See MetoprololBHALLA, S, VIJ, J C, ANAND, B S, VARGHESE, A, and CHUTTANI, H K:

Gastric acid secretion in patients with typhoid fever, 491 (Seealso letter by Vij, et al., 1387)

BIANCHI, F B. See VOLTA, U, LENZI, M, et al.BIANCHI, P A. See BASILISCO, G, BOZZANI, A, et al.

See QUATRINI, M, BASILISCO, G, et al.BIANCHI PORRO, G. See PARENTE, F, LAZZARONI, M, et al.

Bile acid concentrations in gastric juice in erosive oesophagitis, 495acids and glucuronide and sulphate conjugates, profiles in

serum, urine and bile during and after bile drainage, 38, conjugated, in serum and secretions in response to

cholecystokinin/secretin stimulation in children with cystic fibro-sis, 1246

, human, protcins in, sources of, 500Biliary cirrhosis, primary, HLA-DR antigens not associated with

susccptibility to, 625mononuclear cell complemcnt receptor blockade

in, 20D-penicillamine for (Leading article), 109

trial of, 114role of plasmapheresis in, 291thrombocytopenia in, platelet-associatcd im-

munoglobulins as cause of, 1074excretion of radioactivity after intravenous administration of

3H-1,25-dihydroxyvitamin D3, 1240lipid secretion and serum lipids, effect of Rowachol in normal

volunteers, 32sphincterotomy, endoscopic, medium term complications of,

730BINDER, V, HENDRIKSEN, C, and KREINER, S: Prognosis in Crohn'sdisease-based on results from a regional patient group from the

1392

General index

county of Copenhagen, 146See also ELMGREEN, J, BOTH, H, et al.

BINFIELD, P. See THOMPSON, D G, BINFIELD, P, et al.Bismuth, uptake and subcellular localisation in gastrointestinalmucosa of rats after short term administration of colloidalbismuth subcitrate, 364

BJARNASON, 1, MARSH, M N, PRICE, A, LEVI, A j, and PETERS, T J:

Intestinal permeability in patients with coeliac disease anddermatitis herpetiformis, 1214

, and PETERS, T J: In vitro determination of small intestinalpermeability (Letter), 323

, SMETHURST, P, LEVI, A J, and PETERS, T J: Intestinalpermeability to 5'Cr-EDTA in rats with experimentally inducedenteropathy, 579

BLACK, R R. See RHODES J M, BLACK, R R, et al.BLACKSHAW, A J. See CHONG, S K F, BLACKSHAW, A J, et al.Bleeding, gastrointestinal. See Gastrointestinal haemorrhage

varices. See under VaricesBlood, peripheral, mononuclear cells and regulatory T cells in

acute viral hepatitis, 739platelet. See Plateletsupply and function of intestines, 20-year surgical study, 656

BLOOM, S R. See MIAZZA, B M, AL-MUKHTAR, M Y T, et al.

See PRESTON, D M, ADRIAN, T E, et al.See SAGOR, G R, GHATEI, M A, et al.See SAVAGE, A P, GORNACZ, G E, et al.See WOOD, S M, KRAENZLIN, M E, et al.

BLUM, A L. See ETIENNE, A, FIMMEL, C J, et al.BOGAARD, J w. See SMOUT, A J P M, BOGAARD, J W, et al.

BOGOMOLETZ, W V. See FILIPE, M 1, POTET, F, et al.

BOLONDI, L, GAIANI, S, TESTA, s, and LAB6, G: Gall bladder sludgeformation during prolonged fasting after gastrointestinal tractsurgery, 734

Bombesin and somatostatin, influence on plasma enteroglucagonand cell proliferation after intestinal resection in rat, 89

BONFILS, S: New somatostatin molecule for management of endoc-rine tumours (Leading article), 433

Book reviews:ABRAMS, J : Abdominal stomas: indications, operative technique

and patients care, 1984, 759BOLONDI, L, LABO, G, and GANDOLFI, L, eds: Diagnostic ultrasound

in gastroenterology, 1984, 324BRADBEAR, R A, CAMPBELL, C R, and POWELL, L W: 'Gastroenter-

ology revision' illustrated case histories and MCQs, 1984, 982BRANDT, L J, et al.: Gastrointestinal disorders of the elderly, 1984,644

Ciba Foundation Symposia: Mucus and mucosa (New series,109), 1984, 982

Clinics in gastroenterology, Vol 13, No 1, Non-invasive radi-

ology, 1984, 866in immunology and allergy, Vol 3, No 3, Natural mechan-

isrs of immunity, 1983, 324COHEN, S, and SOLOWAY, R D, eds: Peptic ulcer disease, 1985, 867Contemporary issues in gastroenterology, Vol 5, Hormone pro-

ducing tumours of the gastrointestinal tract, 1985, 1389Current hepatology, Vol 4, 1984, 646

opinion in gastroenterology, Vol 1, No 1, Large intestine andgastrointestinal infections, 1985, 1388

topics in nutrition and disease, Vol 12, Absorption andmalabsorption of mineral nutrients, 1984, 1389

DONOWITZ, m, and SHARP G W G, eds: Mechanisms of intestinal

electrolyte transport and regulation by calcium, 1984, 983DRASAR, B s, and BARROW, P A, eds: Intestinal microbiology, 1985,

1273DUBOIS, A, and CASTELL, D o, eds: Esophageal and gastric

emptying, 1984, 983EASTWOOD, G L, ed: Core textbook of gastroenterology, 1984, 644ENTERLINE, H, and THOMPSON J: Pathology of the esophagus, 1984,540

GALANTER, M, ed: Recent developments in alcoholism, Vol 2,

1984, 538

Gastroenterology annual/2, 1984, 982

GILLES-BAILLIEN m, and GILLES, R, eds: Intestinal transport:

fundamental and comparative aspects, 1983, 216

GITNICK G, ed: Controversies in gastroenterology, 1984, 759

red: Current gastroenterology, Vol 4, 1984, 64

GLASS, G B j, and SHERLOCK, P, eds: Progress in gastroenterology,4th ed, 1983, 539

HALL, ed: Alcoholic liver disease: pathobiology, epidemiologyand clinical aspects, 1985, 1097

HELLEMANS, M,and VANTRAPPEN, G, eds: Gastrointestinal tractdisorders in the elderly, 1984, 760

HENRY m, and SWASH, m, eds: Coloproctology and the pelvic floor,1390

HUMBER, A, HOCHESTER, A H c, and ALLGOWER, M: Transsphinctericsurgery of the rectum, 1984, 646

HUGHES, SIR E, CUTHBERTSON, A m, and KILLINgBACK, M K:

Colorectal surgery, 1983, 539JONES, P F, BRUNT, P w, and MOWAT, N A GaIntegrated clinical

science-Gastroenterology, 1985, 1390

KEPPLER, D, et al., eds: Mechanisms of hepatocyte injury and

death, 1984, 646

LINNER, H, ed: Surgery for morbid obesity, 1984, 868

LOS RIOS MAGRINA, E DE: Atlas of therapeutic proctology, 1984,

1272

LUTZ, H, and DEMLING, L, eds: Diagnostic imaging methods in

hepatology, 1984, 867

NAJARIAN, s, and DELANEY, JPM eds: Advances in gastrointestinalsurgery, 1984, 647

OKUDA, K, NAKAYAM, A F, and WONG, J: Intrahepatic calculi, 1984,868

POWELL, L w, and PIPER, D w, eds: Fundamentais of gastroenterol-ogy, 1984, 215

Progress in cancer research and therapy, Vol 29, Markers ofcolonic cell differentiation, 1984, 646

RAVENSCROFJI m m, and SWAN, C H i: Gastrointestinal endoscopyand related procedures, 1984, 216

READ, N w, ed: Irritable bowel syndrome, 1985, 1273

REES, W D w, et al., eds: Case presentations in gastrointestinaldisease, 1985, 1390

SHEPHERD, A P, and GRANGER, D N: Physiology of the intestinalcirculation, 1984, 645

STENGER, R J: Interpretation of liver biopsies (Biopsy interpreta-tion series), 1983, 432

TANNER. m s, and STOCKS. Ra. eds: Neonatal gastroenterologycontemporary issues, 1984, 431

WRIGHT, N, and ALISON, M: The biology of epithelial cell

populations, Vols & 2, 1984, 865

WRIGHT, R A, and HEYMSFIELD, s, eds: Nutritional assessment,1984, 645

1984 Year book of digestive diseases, 1984, 1388Books received, 105, 324, 540, 868, 983, 1098, 1390BOOTH, C C: What has technology done to gastroenterology?, 1088BOOTH, I W. See PINKERTON, C R, BOOTH, I W, et al.BOOTH, J. See BARR L C, BOOTH, j, et al.BORIES, C. See MODIGLIANI, R, BORIES, c, et al.BORIONI, D. See ALDI, F, FERRARINI, F, et al.BORTOLOTTI, F. See FARCI, P, BARBERA, c, et al.BORZIO, M. See CALDARA, R, BARBIERI, C, et al.BOSCHI, S. See CAMPIERI, M, LANFRANCHI, G A, et al.BOTH, H. See ELMGREEN, J, BOTH, H, et al.Bowel diseases in homosexual men (Leading article), 869

See also Intestine(s)BOWN, S G, SWAIN C P, STOREY, D W, COLLINS, C, MATTHEWSON, K,

SALMON, P R, and CLARK, C G: Endoscopic laser treatment ofvascular anomalies of the upper gastrointestinal tract, 1338

BOYD, E, and MARKS, I N: Appropriate statistical test in comparativeulcer healing studies (Letter), 643

BOYD, J F: Pathology of the alimentary tract in Salmonellatyphimurium food poisoning, 935

1393

General index

BOYLE, S. See CHONG, S K F, BLACKSHAW, A J, et al.BOYLSTON, A. See WEBER, J N, CARMICHAEL, D J, et al.BOZZANI, A. See BASILISCO, G, BOZZANI, A, et al.BRAGANZA, J M, and ACHESON, D W K: Comparative radiological and

morphological study of human pancreas (Letter), 1095BRAILLON, A, CAPRON, J P, HERVt, M A, DEGUoI, C, and QUENUM, C:

Liver in obesity, 133BRAMBLE, M G, ZUCOLOTO, S, WRIGHT, N A, and RECORD, C 0: Acute

gluten challenge in treated adult coeliac disease: a morphometricand enzymatic study, 169

BRANDES, J-W. See SCHMITZ-MOORMANN, P, HIMMELMANN, G W, et al.Breath, exhaled, hydrogen measurements during investigation of

gastrointestinal disease, extra intestinal influences on, 1349-, flatus and faeces, analysis for methane excretion, 69;

(Letters), 1270- hydrogen profile after solid meal containing unabsorbable

carbohydrate, interpretation of, 834test, lactulose hydrogen, in evaluation of effect of loperamide

and naloxone on mouth-to-caecum transit time, 700BRIGNOLA C. See CAMPIERI, M, LANFRANCHI, G A, et al.BRISTOL, J B. See ALLAN, A, BRISTOL, J B, et al.British Society of Gastroenterology, President (1985-86), DrGerard Patrick Crean, 1099

BROECKAERT, L. See RUTGEERTS, P, VAN GOMPEL, F, et al.BRON, B A. See ETIENNE, A, FIMMEL, C J, et al.BROWN, B. See KEOHANE P P, GRIMBLE, G K, et al.BROWN, C. See READ, N W, AL-JANABI, M N, et al.BROWN, M R. See LENZ, H J, MORTRUD, M T, et al.BROWN, R. See HARRIES, A D, BROWN, R, et al.Brunner's gland hyperplasia, degree of, in chronic renal failure,

relation to serum pepsinogen group II concentration, 198glands, epidermal growth factor secretion from, adrenergic

effects on, 920BRYDON, W G. See MCKAY, L F, EASTWOOD, M A, et al.BUKHAVE, K. See SPEELMAN, P, RABBANI, G H, et al.BULLEN, A W. See FOSTER, P N, BULLEN, A W, et al.BUNCE, M. See COTrONE, M, BUNCE, M, et al.BURFORD-MASON, A P, and WILLOUGHBY, J M T: Specific food

intolerance (Letter), 980BURINI, R C. See RODRIGUES, M A M, DE CAMARGO, J L V, et al.

BURKE, M. See DANESH, B J Z, BURKE, M, et al.BURMAN, J F, JENKINS, W J, WALKER-SMITH, J A, PHILLIPS, A D,

SOURIAL, N A, WILLIAMS, C B, and MOLLIN, D L: Absent ilealuptake of IF-bound vitamin B12 in vivo in the Imerslund-Grasbeck syndrome (familial vitamin B12 malabsorption withproteinuria) (Case report), 311

BUSH, A. See THOMPSON, J N, BARR, J A, et al.BYTH, K. See MCINTOSH, J H, BYTH, K, et al.

CABALLERIA, J. See NEUBERGER, J, CHRISTENSEN, E, et al.Caecum, rat, not rendered susceptible to carcinogenesis by distal

transposition, 718CALAM, J. See COOPER, R G, DOCKRAY, G J, et al.Calcitonin gene related peptide inhibition of basal and pentagas-

trin, histamine and bethanecol stimulated gastric acid secretion,550

Calcium and vitamin D metabolism, regulation after gastrectomy,252

CALDARA, R, BARBIERI, C, PIEPOLI, V, BORZIO, M, and MASCI, E: Effect

of L-dopa with and without inhibition of extracerebral dopadecarboxylase on gastric acid secretion and gastrin release inman, 1014

CALDER, 1. See FARAH, D A, CAkLDER, I, et al.See MACKENZIE, J F, CALDER, I, et al.

CALZIA, R. See FARCI, P, BARBERA, C, et al.CAMBONI, G. See BASILISCO, G, BOZZANI, A, et al.CAMPIERI, M, LANFRANCHI, G A, BOSCHI, S, BRIGNOLA, C, BAZZOCCHI, G

GIONCHEIlTI, P, MINGUZZI, M R, BELLUZZI, A, and LAB6, G: Topicaladministration of 5-aminosalicylic acid enemas in patients with

ulcerative colitis: studies on rectal absorption and excretion, 400Campylobacter colitis, histological, immunohistochemical and

ultrastructural findings in, 945Campylobacter pyloridis in peptic ulcer disease, microbiology,

pathology, and scanning electron microscopy, 1183CANN, P A. See READ, N W, AL-JANABI, M N, et al.CAPORASO, N. See FARCI, P, BARBERA, C, et al.CAPRON, D. See SCEMAMA-CLERGUE, J, DOUTRELLOT-PHILIPPON, C, et

al.CAPRON, J P. See BRAILLON, A, CAPRON, J P, et al.Carbohydrate, unabsorbable, breath hydrogen profile after solidmeal containing, interpretation of, 834

Carcinogenesis, rat caecum not rendered susceptible by distaltransposition to, 718

Carcinoid tumour, ileal, bleeding, endoscopic diagnosis of (Letter),431

tumours, gastric, and inhibition of gastric acid secretion(Leading article), 1279-,-1association with long lasting unsurmountable

histamine H2 blockade with loxtidine in rat, 1284Carcinoma, colorectal, incidence in proctocolitis, study of 959 cases

over 40 years, 43-, -, induced, in rat, effect of warfarin on cell kinetics,

epithelial morphology and tumour incidence in, 807, primary, cell kinetics and in vitro clonogenicity of,

clinicopathological relationships and implications for chemo-therapy, 267-, gastric, risk of, incomplete sulphomucin-secreting and other

types of intestinal metaplasia as indicators of, prospective3-centre study, 1319

, pancreatic, enzyme immunoassay of pancreatic oncofetalantigen as marker of, 450

CARMICHAEL, D J. See WEBER, J N, CARMICHAEL, D J, et al.CARMINATI, G. See PIGNATA C, TRONCONE, R, et al.CARRATU, R. See PAOLUZI, P, RICOTlA, G, et al.CARR-LOCKE, D L. See GOODMAN, A J, NEOPTOLEMOS, J P, et al.CARTER, D C. See UTLEY, R J, SALIM, A S M, et al.CASSANI, F. See VOLTA, U, LENZI, M, et al.CASTANEDA SANZ, S, HERRERO-BEAUMONT, G, and TORNERO MOLINA, J:

Protein-losing enteropathy caused by systemic lupus erythemato-sus (Letter), 757

CAUDA, R. See BARNABA, V, TAMBURRINI, E, et al.Caved-S maintenance therapy in prevention of symptomatic gastric

ulcer recurrence, 2-year comparison with cimetidine, 599;(Erratum), 984

plus ranitidine and ranitidine alone in treatment of gastriculceration, comparative study (Clinical trial), 1377

Cellular proliferation and plasma enteroglucagon after intestinalresection in rat, influence of somatostatin and bombesin, 89

Cereal proteins, reticulin binding property in vitro, role inpathogenesis of coeliac disease?, 1204

CERF-BENSUSSAN, N, GUY-GRAND, D, and GRISCELLI, C: Intraepitheliallymphocytes of human gut: isolation, characterisation and studyof natural killer activity, 81

CHADWICK, V S. See ADEYEMI, E 0, NEUMANN, S, et al.See SAVERYMUTTU, S H, HODGSON, H J F, et al.See SAVERYMUTTU, S H, PETERS, A M, et al.

CHALMERS, D M. See FOSTER, P N, BULLEN, A W, et al.CHAN, K W. See COODE, P E, CHAN, K W, et al.CHAN, Y T. See COODE, P E, CHAN, K W, et al.CHAPMAN, B J. See BECKETT, G J, CHAPMAN, B J, et al.CHAPPELL, M E. See ALLISON, M C, RENFREW, C C, et al.CHAUVEINC, P. See FILIPE, M I, POTEI, F, et al.Cholangiopancreatography, retrograde, endoscopic. See ERCPCholecystokinin/secretin stimulation in children with cystic fibrosis,

conjugated bile acids in serum and secretions in response to,1246

Cholera, acute, increased jejunal prostaglandin E2 concentrationsin, 188

toxin, intestinal response to, prostaglandins not mediators of,

1394

General index

680Cholestasis in amoebic liver abscess, 140Cholestatic jaundice in haemolytic-uraemic syndrome (Case re-

port), 315CHONG, S K F, BLACKSHAW, A J, BOYLE, S, WILLIAMS, C B, andWALKER-SMITH, J A: Histological diagnosis of chronic inflamma-tory bowel disease in childhood, 55

CHRISTENSEN, E. See NEUBERGER, J, CHRISTENSEN, E, et al.CHRISTIANSEN, C. See NILAS, L, CHRISTIANSEN, C, et al.CHRISTIANSEN, J. See LOUD, F B, HOLST, J J, et al.

See NILAS, L, CHRISTIANSEN, C, et al.CHRISTOFIDES, N D. See PRESTON, D M, ADRIAN, T E, et al.CHUITANI, H K. See BHALLA, S, VIJ, J C, et al.-. See VIJ, i C, ANAND, B S, et al.Cimetidine and omeprazole, effect on aspirin- and taurocholate-

induced gastric mucosal damage in rat, 770effect on enzyme inactivation, bile acid precipitation, and

lipid solubilisation in pancreatic steatorrhoea due to cysticfibrosis, 892

on gastric secretion and duodenogastric reflux, 766healing of duodenal ulcer and ulcer persistence or relapse,

influence of cigarette smoking, 1333maintenance therapy in prevention of symptomatic gastric

ulcer recurrence, 2-year comparison with Caved-S, 599; (Erra-tum), 984

treatment of completely and incompletely healedduodenal ulcers, outcome of (Clinical trial), 1080

regimens, separate, for reducing postprandial and nocturnalacid secretions, duodenal ulcer healing by, differences inpathophysiology in, 1038

resistance, development in Zollinger-Ellison syndrome (Casereport), 1263

versus ranitidine in short term healing of duodenal ulcers(Letters), 642

CIRIACO, M. See PIGNATA, C, TRONCONE, R, et al,Cirrhosis, alcoholic, ascitic fluid pH in, diagnosis of spontaneous

bacterial peritonitis from, reevaluation of, 332decompensated, renal function enhancement with

ornipressin in (Case report), 1385and ascites, renal function impairment induced by posture

change in, 629and portal hypertension, propranolol pharmacology in, 14biliary, primary, HLA-DR antigens not associated with

susceptibility to, 625mononuclear cell complement receptor blockade

in, 20D-penicillamine for (Leading article), 109

trial of, 114role of plasmapheresis in, 291thrombocytopenia in, platelet-associated im-

munoglobulins as cause of, 1074, clinical course in young adults and therapeutic potential of

liver transplantation, 1359of liver in young adults, association with alcohol and

parenteral heroin abuse (Leading article), 8propranolol disposition in (Letter), 865variceal bleeding in, long term management of, oral

metroprolol compared with injection sclerotherapy for (Clinicaltrial), 421

Cisapride, effect on gastric emptying in dyspepsia, measurementof, 352

on interdigestive and postprandial motor activity ofdistal oesophagus, 246

Citrate in oral rehydration therapy (Letters), 429CLARK, C G. See BOWN, S G, SWAIN, C P, et al.CLARK, J. See PRICE, A B, LEVI, J, et al.CLARK, L. See MCCREADY, D R, CLARK, L, et al.CLARK, M L. See MORIARTY, K J, HEGARTY, J E, et al.

See MORIARTY, K J, KELLY, M J, et al.See MORIARTY, K J, ROLSTON, D D K, et al.

See ROLSTON, D D K, FARTHING, M J G, et al.CLARKE, J M F. See MARSTON, A, CLARKE, J M F, et al.CLASSEN, M. See SCHMIEGEL, W H, KREIKER, c, et al.CLUYSENAER, O i j, and VAN TONGEREN, J H M: Coeliac disease

presenting with intestinal pseudo-obstruction (Letter), 538COBDEN, I. See HAMILTON, I, COBDEN, I, et al.COCHAND-PRIOLLET, B. See MODIGLIANI, R, BORIES, c, et al.COELHO, K I R. See RODRIGUES, M A M, DE CAMARGO, J L v, et al.Coeliac disease, adult, treated, acute gluten challenge in, mor-

phometric and enzymatic study, 169and dermatitis herpetiformis, intestinal permeability in,

1214, childhood and adult, active, value of antibodies to

gliadin detected by immunoflourescence and micro-ELISAmethod as markers of, 667- -, DR and non-DR Ia allotypes associated with suscepti-

bility to, 1210-- , frequency of, changing patterns in analysis of Coeliac

Society membership, 175impaired suppressor activity in children affected by, 285in vitro determination of small intestinal permeability in

(Letters), 322- , pathogenesis of, role for reticulin binding property of

cereal proteins in vitro in?, 1204presenting with intestinal pseudo-obstruction (Letter),

538; (Letter), 758- -, splenic function in, genetic influences on, 1004Colitis, idiopathic, acute exacerbations of, oral vancomycin as

adjunctive treatment in (Clinical trial), 1380COHEN, D L. See KIBBLER, C C, COHEN, D L, et al.COHEN, L B, AMBINDER, E P, WOLKE, A M, FIELD, S P, and SCHAFFNER,

F: Role of plasmapheresis in primary biliary cirrhosis, 291COHEN, M M. See MCCREADY, D R, CLARK, L, et al.Colectomy, total, in acute fulminating amoebic colitis, survival

after (Case report), 301Colitis, amoebic, fulminating, acute, survival after total colectomy

in (Case report), 301Crohn's, maintenance of, role of faecal stream in, 279distal, poorly absorbed prednisolone enema in, therapeutic

benefits from, trial of, 822due to Campylobacter, histological, immunohistochemical

and ultrastructural findings in, 945, ulcerative, 5-aminosalicylic acid enemas in, topical adminis-

tration and rectal absorption and excretion of, 400, and Crohn's disease, faecal mucus-degrading glycosi-

dases in, 761and HLA phenotype, 952apparent, Kaposi's sarcoma qf bowel presenting as

(Case report), 295epidemiological studies, comparison of (Progress

report), 968, , prognosis, long term, based on follow-up of all patients

from county of Copenhagen (1960-78), 158Collagenolytic enzyme inhibitors in serum in chronic liver dis-

orders, 1364COLLIER, D ST J, and PAIN, J A: Non-steroidal anti-inflammatory

drugs and peptic ulcer perforation, 359; (Letter), 981COLLIER, N. See THOMPSON, J N, BARR, J A, et al.COLLIN, J. See WATKINS, R M, DENNISON, A R, et al.

COLLINA, A. See VOLTA, U, LENZI, M, et al.COLLINS, B J, CROTHERS, G, MCFARLAND, R J, and LOVE, A H G: Bile

acid concentrations in the gastric juice of patients with erosiveoesophagitis, 495

See also SPENCE, R A J, COLLINS, B j, et al.COLLINS, C. See BOWN, S G, SWAIN, C P, et al.COLLINS, J D. See BASSENDINE, M F, COLLINS, J D, et al.

Colon, adenocarcinoma of, elution of cytomegalovirus antibodiesfrom, 1053

, glucose perfusion of, hyperenteroglucagonaemia and smallintestinal mucosal growth in rats after, 518

1395

General index

, mechanical properties of, comparison between African andEuropean colon in vitro, 384

Colorectal carcinoma, incidence in proctocolitis, study of 959 casesover 40 years, 43- , induced, in rat, effect of warfarin on cell kinetics,

epithelial morphology and tumour incidence in, 807, primary, cell kinetics and in vitro clonogenicity of,

clinicopathological relationships and implications for chemo-therapy, 267

Complement dysfunction in Crohn's disease, familial occurrence

of, correlation with intestinal symptoms and hypercatabolism ofcomplement, 151

receptors on mononuclear cells, blockade of, in primarybiliary cirrhosis, 20

COMPSTON, J E. See LEDGER, J E, WATSON, G J, et al.Computer-aided selection of diagnostic tests in jaundiced patients,

961Computer-assisted tomography scanning in diagnosis and manage-ment of hepatic artery aneurysm (Case report), 752

Constipation of different types, balloon expulsion from rectum in,1049

CONTALDO, F, MANCINI, M, REED, L A, et al.: Liver and obesity(Letter), 1096

CONTE, D. See BASILISCO, G, BOZZANI, A, et al.COODE, P E, CHAN, K W, and CHAN Y T: Polyps and diverticula of the

large intestine: a necropsy survey in Hong Kong, 1045COOK, J L. See POYNTER, D, PICK, C R, et al.COOKE, T. See GOETING, N, TROTrER, G A, et al.COOPER, A J. See TROTrER, G A, MORGAN, G R, et al.COOPER, M J. See CORFIELD, A P, COOPER, M J, et al.COOPER, R G, DOCKRAY, G J, CALAM, j, and WALKER, R: Acid and

gastrin responses during intragastric titration in normal subjectsand duodenal ulcer patients with G-cell hyperfunction, 232

COPE, L. See THOMPSON, J N, BARR, J A, et al.CORAZZA, G R, TABACCHI, P, FRISONI, M, and GASBARRINI, G: DR and

non-DR Ia allotypes are associated with susceptibility to coeliacdisease, 1210

COREMANS, G. See RUTGEERTS, P, VAN GOMPEL, F, et al.CORFIELD, A P, COOPER, M J, and WILLIAMSON, R C N: Acute

pancreatitis: a lethal disease of increasing incidence, 724Corrections, 540, 984COSTELLO, F T. See LEE, F i, and COSTELLO, F T

COTrON, P B. See DANESH, B J Z, BURKE, M, et al.See GILINSKY, N H, DEL FAVERO, G, et al.See SHORVON, P J, COT1ON, P B, et al.

COTTONE, M, BUNCE, M, TAYLOR, C J, TING, A, and JEWELL, D P:

Ulcerative colitis and HLA phenotype, 952Crean, Dr Gerard Patrick (President, BSG, 1985-86), 1099CRITCHLEY, M. See BAXTER, J N, GRIME, J S, et al.CROFTON, M E. See SAVERYMUTTU, S H, PETERS, A M, et al.Crohn's colitis, maintenance of, role of faecal stream in, 279

disease, active, comparative trial of prednisolone and elemen-tal diet plus non-absorbable antibiotics in, 994

and ulcerative colitis, faecal mucus-degrading glycosi-dases in, 761

, complement dysfunction in, familial occurrence of,correlation with intestinal symptoms and hypercatabolism ofcomplement, 151- -, granulocyte migration to diseased bowel in, in vivo

assessment of, 378in elderly, 461in two married couples (Case reports), 1086incidence and prevalence in Blackpool (1968-80), 274low residue or normal diet in, prospective study in

Italian patients, 989management of, diet in (Leading article), 985plasma and erythrocyte selenium concentrations during

total parenteral nutrition in, 50, prognosis based on follow-up of all patients from county

of Copenhagen (1960-78), 146

- ,1 vitamin D status in, association with nutrition anddisease activity, 1197

Cronkhite Canada syndrome, features and aetiology (Case report),531

CROSSLEY, I R, and WILLIAMS, R: Spontaneous bacterial peritonitis(Leading article), 325

CROTHERS, G. See COLLINS, B J, CROTHERS, G, et al.CRUICSHANK, J K. See KIBBLER, C C, COHEN, D L, et al.Cryoprecipitate treatment, acute fulminant non-A, non-B hepatitis

leading to chronic active hepatitis after (Case report), 639Crypt cell production rate in ulcerative proctocolitis, differential

increments in remission and relapse, 999(+)-Cyanidanol-3, effect on chronic active hepatitis (Clinical trial),

975Cystic fibrosis, conjugated bile acids in serum and secretions in

response to cholecystokinin/secretin stimulation in children with,1246

, pancreatic steatorrhoea due to, effect of cimetidine onenzyme inactivation, bile acid precipitation, and lipid solubilisa-tion in, 892

Cytomegalovirus antibodies, elution from adenocarcinoma ofcolon, 1053

DAHL, G. See TAGESSON, C, FRANZEN, L, et al.DANESH, B J Z, BURKE, M, NEWMAN, J, AYLOTT, A, WHITFIELD, P, and

COTTON, P B: Comparison of weight, depth, and diagnosticadequacy of specimens obtained with 16 different biopsy forcepsdesigned for upper gastrointestinal endoscopy, 227

DAVIDSON, G P. See ROBB, T A, DAVIDSON, G P, et al.DAWSON, A M. See KINGHAM, J G C, and DAWSON, A M

See MORIARTY, K J, HEGARTY, J E, et al.See ROLSTON, D D K, FARTHING, M J G, et al.

DAWSON, D J, and WHITWELL, H: Coeliac disease presenting withintestinal pseudo-obstruction (Letter), 758

DAWSON, J, GERTSCH, P. MOSIMANN. F, WEST, R, and ELIAS, E:

Endoscopic variceal pressure measurements: response to isosor-bide dinitrate, 843

DAWSON, P A. See FILIPE, M I, POTET, F, et al.DAY, N E. See MANOUSOS, 0, DAY, N E, et al.DE BELDER, A. See THOMPSON, D G, BINFIELD, P, et al.DE CAMARGO, J L V. See RODRIGUES, M A M, DE CAMARGO, J L V, et al.DE COCK, K M, GOVINDARAJAN, s, and REDEKER, A G: Acute delta

hepatitis without circulating HBsAg (Case report), 212DEGOTT, C. See BERCOFF, E, BERNUAU, J, et al.

See BRAILLON, A, CAPRON, J P, et al.DEL FAVERO, G. See GILINSKY, N H, DEL FAVERO, G, et al.DELLE FAVE, G. See KOHN, A, ANNIBALE, B, et al.Delta agent, detection and clinical significance, 1

infection in children, 4hepatitis, acute, without circulating HBsAg (Case report), 212

DENNISON, A R. See WATKINS, R M, DENNISON, A R, et al.Dermatitis herpetiformis and coeliac disease, intestinal permeabil-

ity in, 1214DESPORTES, I. See MODIGLIANI, R, BORIES, C, et al.DEUTSCH, E. See LENZ, K, DRUML, W, et al.DEWAR, P J. See BASSENDINE, M F, DEWAR, P J, et al.DHUMEAUX, D. See SAINT-MARC GIRARDIN, M-F, LE MINOR, M, et al.-. See SCEMAMA-CLERGUE, J, DOUTRELLOT-PHILIPPON, C, et al.Diarrhoea and malabsorption in AIDS, 4 cases showing frequency

of unusual protozoan infestations, 179DICK, R D. See KIBBLER, C C, COHEN, D L, et al.DICKINSON, R J, O'CONNOR, H J, PINDER, I, HAMILTON, I, JOHNSTON, D,and AXON, A T R: Double blind controlled trial of oral vancomycinas adjunctive treatment in acute exacerbations of idiopathiccolitis, 1380

Diet and diverticulosis, new evidence (Leading urticle), 541and drinking habits in relation to development of alcoholic

pancreatitis, 882and other factors in aetiology of diverticulosis, epidemio-

1396

General index

logical study in Greece, 544-, elemental, plus non-absorbable antibiotics in active Crohn's

disease, comparative trial with prednisolone, 994in management of Crohn's disease (Leading article), 985low residue or normal, in Crohn's disease, prospective study

in Italian patients, 9893H-1,25-Dihydroxyvitamin D3, intravenous administration of, bili-

ary excretion of radioactivity after, 1240

DINCSOY, H P. See ORENSTEIN, M S, TAVITIAN, A, et al.

Dioctyl sodium sulphosuccinate, mechanism of action in humanjejunum, 1008

Diverticula and polyps of large intestine, necropsy survey in HongKong, 1045

Diverticular disease of sigmoid colon, elastosis in, 258Diverticulosis, aetiology of, diet and other factors in, epidemiolo-

gical study in Greece, 544and diet, new evidence (Leading article), 541

DOCKRAY, G J. See COOPER, R G, DOCKRAY, G J, et al.DOLBY, J M. See PRICE, A B, LEVI, J, et al.L-Dopa with and without inhibition of extracerebral dopa decar-

boxylase, effect on gastric acid secretion and gastrin release,1014

DOUTRELLOT-PHILIPPON, C. See SCEMAMA-CLERGUE, J, DOUTRELLOT-

PHILIPPON, C, et al.DOWLATSHAHI, K, EVANDER, A, WALTHER, B, and SKINNER, D B:

Influence of morphine on the distal oesophagus and loweroesophageal sphincter: a manometric study, 802

DR and non-DR Ia allotypes associated with susceptibility tocoeliac disease, 1210

Drinking habits and diet in relation to development of alcoholicpancreatitis, 882

DRUML, W. See LENZ, K, DRUML, w, et al.D'UBALDI, A. See LEVENSTEIN, S, PRANTERA, C, et al.DUCROT, F. See JIAN R, DUCROT, F, et al.DUDLEY, F. See RUBINSTEIN, D, MCINNES, I, et al.DUGGAN, J M: Conservative treatment of gastrointestinal haemor-

rhage (Letter), 1272See also ROFE, S B, DUGGAN, J M, et al.

DUHRA, P M, QUIGLEY, E M M, and MARSH M N: Chylous ascites,intestinal lymphangiectasia and the 'yellow-nail' syndrome (Casereport), 1266

DUNSCOMBE, P L. See PRICE, A B, LEVI, J, et al.Duodenitis and duodenal ulceration, duodenal bulb plasma cells in,

1032Duodenogastric reflux and gastric secretion, effect of cimetidine,766

Duodenoscopic sphincterotomy, percutaneous transhepatic assist-ance for, 1373

Duodenum, oesophagus and antrum, histological appearances andcorrelation with symptoms in duodenal ulcer, 95

ulcer, and duodenitis, duodenal bulb plasma cells in, 1032changes in solid and liquid gastric emptying in, 689cigarette smoking, gastric acid secretion and serum

pepsinogen I concentrations in, 1327failing to heal (Letter), 105gastric acid and pancreatic polypeptide responses to

modified sham feeding in, and increased basal vagal tone in somepatients, 776

gastrin sensitivity in, 485healing by separate cimetidine regimens for reducing

postprandial and nocturnal acid secretions, differences inpathophysiology in, 1038

complete and incomplete, outcome of cimetidinemaintenance treatment after (Clinical trial), 1080

short term, cimetidine versus ranitidine for(Letters), 642

, influence of cigarette smoking on healing by cimetidineand ulcer persistence or relapse, 1333

pathogenesis of, and histamine (Leading article), 1159patients with G-cell hyperfunction, acid and gastrin

responses during intragastric titration in, 232, , prevention in rat by combined ranitidine and sucralfate

in subtherapeutic doses, 603-,- , prostaglandin synthesis in duodenal mucosa in, 237DUURSMA, G C. See VAN SPREEUWEL, J P, DUURSMA, G C, et al.DYSON, E H. See BECKETT, G J, CHAPMAN, B j, et al.Dyspepsia, gastric emptying in, measurement of, and effect of

cisapride, 352

EARLAM, R J, AMERIGO, J, KAKAVOULIS, T, and POLLOCK, D J:

Histological appearances of oesophagus, antrum and duodenumand their correlation with symptoms in patients with a duodenalulcer, 95

EASTWOOD, M A. See MCKAY, L F, EASTWOOD, M A, et al.See WATTERS, D A K, SMITH, A N, et al.

EBERL, W. See SCHMIEGEL, W H, KREIKER, C, et al.EDDLESTON, A L W F. See AL-AGHBAR, M N A, NEUBERGER, J, et al.EGENSE, E. See LOUD, F B, HOLST, J j, et al.ELASHOFF, J D. See MOGARD, M H, MAXWELL, v, et al.Elastase, human leucocyte, circulating, in inflammatory bowel

disease, 1306Elastosis in diverticular disease of sigmoid colon, 258ELDER, J B: Inhibition of acid and gastric carcinoids (Leading

article), 1279Electrohydrothermoprobe as alternative to laser therapy in acute

gastrointestinal haemorrhage, results of trial, 477Electrolytes, gastric acid and pepsin, basal, sham feed- and

pentagastrin-stimulated, after omeprazole 20 mg and 40 mgdaily, 1018

ELIAS, E. See DAWSON, J, GERTSCH, P, et al.-. See RHODES, J M, GALLIMORE, R, et al.ELISA. See Micro-ELISAELLIS, W R. See WINSTANLEY, P A, ELLIS, W R, et al.ELMGREEN, J, BOTH, H, and BINDER, v: Familial occurrence ofcomplement dysfunction in Crohn's disease: correlation withintestinal symptoms and hypercatabolism of complement, 151

ELTON, R A. See WATTERS, D A K, SMITH, A N, et al.Encephalopathy, hepatic, chronic, lactitol compared with lactulose

in treatment of (Clinical trial), 415Endocrine tumours, pancreatic, somatostatin (SMS 201-995) treat-ment of, symptomatic and peptide responses, 438- -, somatostatin (SMS 201-995) for management of

(Leading article), 433Endoscopic biliary sphincterotomy, medium term complications of,730

diagnosis of bleeding ileal carcinoid tumour (Letter), 431- fine needle puncture method in assessment of intravascular

oesophageal variceal pressure under basal conditions, afterValsalva's manoeuvre and after glyceryltrinitrate application,525

laser treatment of vascular anomalies of upper gastrointestinaltract, 1338

retrieval of miniature battery (Letter), 215retrograde cholangiopancreatography. See ERCPsclerotherapy using absolute alcohol, 120variceal pressure measurements, response to isosorbide

dinitrate, 843Endoscopy, gastrointestinal, upper, biopsy forceps designed for,comparison of weight, depth, and diagnostic adequacy ofspecimens obtained with 16 different types, 227

ENGLISH, J. See MCINTYRE, P B, MACRAE, F A, et al.ENLOW, R W. See NOVICK, D M, ENLOW, R W, et al.Enteritis die to enteropathogenic Escherichia coli, evaluation of

gnotobiotic piglet as model of human infection, 570Enteroglucagon, plasma levels, and cell proliferation after intes-

tinal resection in rat, influence of somatostatin and bombesin, 89Enteropathy, experimental, intestinal permeablity to 51Cr-EDTA

in rats with, 579, protein-losing, due to systemic lupus erythematosus (Let-

1397

General index

ters), 757Enzyme immunoassay of pancreatic oncofetal antigen as marker of

pancreatic cancer, 450Epidermal growth factor secretion from Brunner's glands, adrener-

gic effects on, 920Epigastric impedance as non-invasive method for assessment of

gastric emptying and motility, 607ERCP in chronic alcohol induced pancreatitis, comparison with

oral (PABA) pancreatic function test and secretin-pancreozymintest, 1257

Erythrocyte and plasma selenium concentrations during totalparenteral nutrition in Crohn's disease, 50

Escherichia coli, enteropathogenic, enteritis due to, evaluation ofgnotobiotic piglet as model of human infection, 570

Ethylenediaminetetraacetate, 5'Cr-labelled, intestinal permeabilityto, in rats with experimental enteropathy, 579

ETIENNE, A, FIMMEL, C J, BRON, B A, LOIZEAU, E, and BLUM, A L:

Evaluation of pirenzepine on gastric acidity in healthy volunteersusing ambulatory 24 hour intragastric pH-monitoring, 241

EVANDER, A. See DOWLATSHAHI, K, EVANDER, A, et al.EVANS, P. See YV,ILLIAMS, N S, EVANS, P, et al.EWE, K. See STARITZ, M, PORALLA, T, et al.EYRE-BROOK, I. See MCCORMACK, T T, SIMS, J, et al.

FABIANI, B. See FILIPE, M 1, POTET, F, et al.FABRICIUS, P J, GYDE, S N, SHOULER, P, KEIGHLEY, M R B, ALEXANDER-

WILLIAMS, J, and ALLAN, R N: Crohn's disease in the elderly, 461Faecal extracts, desialation and desulphation of normal and

inflammatory bowel disease rectal mucus by, histochemicaldemonstration of, 1312

mucus-degrading glycosidases in ulcerative colitis and Crohn'sdisease, 761

stream, role in maintenance of Crohn's colitis, 279sulphatase in health and in inflammatory bowel disease, 466

Faeces, breath and flatus, analysis for methane excretion, 69;(Letters), 1270

FAIRCLOUGH, P D. See LUCEY, M R, WASS, J A H, et al.See MORIARTY, K J, HEGARTY, J E, et al.

FALT, K. See ARVIDSSON, S, FALT, K, et al.FARAH, D A, CALDER, 1, BENSON, L H, and MACKENZIE, J F: Specific

food intolerance: its place as a cause of gastrointestinal symp.-toms, 164 (see also Letter, 980)

FARCI, P, BARBERA, C, NAVONE, C, BORTOLOTTI, F, VAJRO, P, CAPORASO,N, VEGNENTE, A, ANSALDI, N, RIZZETTO, M, l'OLENTINO, P, and

CALZIA, R: Infection with the delta agent in children, 4FARRINGTON, K. See JEFFREY, G, KIBBLER, C C, et al.FARRIS, E. See PIGNATA, C, TRONCONE, R, et al.FARTHING, M J G. See ROLSTON, D D K, FARTHING, M J G, et al.Fasting, prolonged, after gastrointestinal tract surgery, gall bladder

sludge formation during, 734Feeding. See Sham feedingFELCE-DACHEZ, M. See MIAZZA, B M, AL-MUKHIAR, M Y T, et al.FENZY, A. See FILIPE, M 1, POTET, F, et al.FERGUSON, D J P. See GIBSON, P R, HERMANOWICZ, A, et al.FERRARINI, F. See BALDI, F, FERRARINI, F, et al.FIELD, S P. See COHEN, L B, AMBINDER, E P, et al.FILALI, A. See MIAZZA, B M, AL-MUKHTAR, M Y et al.FILIPE, M I, POTET, F, BOGOMOLETZ, W V, DAWSON, P A, FABIANI, B,CHAUVEINC, P, FENZY, A, GAZZARD, B, GOLDFAIN, D, and ZEEGEN,R: Incomplete sulphomucin-secreting intestinal metaplasia forgastric cancer: preliminary data from a prospective study fromthree centres, 1319

See also BARR, L C, BOOTH, j, et al.FIMMEL, C J. See ETIENNE, A, FIMMEL, C J, et al.FINE, D R. See ZENTLER-MUNRO, P L, FINE, D R, et al.FINLAY, D B L. See GOODMAN, A J, NEOPTOLEMOS, J P, et al.FINN, T. See SPENCER, J, FINN, T, et al.FIOCCHI, C. See STALNIKOWICZ, R, GODER, K, et al.FITZGERALD, O: Types of pancreatitis (Letter), 430

FITZHARRIS, B. See MULLOCK, B M, SHAW, L J, et al.

Flatus, breath and faeces, analysis for methane excretion, 69;(Letters), 1270

FLUCK, P A. See POYNTER, D, PICK, C R, et al.Fluid secretion in human jejunum, inhibition by nufenoxole, 75FOK, K-H. See LAM, S-K, LAI, C-L, et al.FOLSCH U R. See SCHMITZ-MOORMANN, P, HIMMELMANN, G W, et al.Food intolerance, specific, as cause of gastrointestinal symptoms,

164; (Letters), 980poisoning with Salmonella typhimurium, alimentary tract

pathology in, 935Forceps, biopsy, designed for upper gastrointestinal endoscopy,comparison of weight, depth, and diagnostic adequacy ofspecimens obtained with 16 different types 227

FOSSARD, D P. See GOODMAN, A J, NEOPTOLEMOS, J P, et al.FOSTER, P N, BULLEN, A W, ROBERTSON, D A F, CHALMERS, D M, and

LOSOWSKY, M S: Development of impaired splenic function in

intestinal lymphangiectasia (Case report), 861FOTINO, M. See NOVICK, D M, ENLOW, R W, et al.FOULDS, I S. See WOOD, M L, FRENCH, M A, et al.FRANZEN, L. See TAGESSON, C, FRANZEN, L, et al.FREEMAN, K, ANTHONY, P P, MILLER, D S, and WARIN, A P: CronkhiteCanada syndrome: a new hypothesis (Case report), 531

FRENCH, M A. See WOOD, M L, FRENCH, M A, et al.FRISONI, M. See CORAZZA, G R, TABACCHI, P, et al.

G cell hyperfunction, duodenal ulcer patients with, acid and gastrinresponses during intragastric titration in, 232

GAIANI, S. See BOLONDI, L, GAIANI, S, et al.GALIAN, A. See MODIGLIANI, R, BORIES, C, et al.Gall bladder emptying in normal subjects, relationship to gastricemptying of solids, 342

sludge formation during prolonged fasting after gastro-intestinal tract surgery 734

stone detection after acute pancreatitis, 125- pancreatitis, acute, pathogenesis of, and effect of

injection pressure and volume on pancreas, 615GALLIMORE, R. See RHODES, J M, BLACK, R R, et al.

See RHODES, J M, GALLIMORE, R, et al.GALPIN, S. See WELLER, I V D, LOK, A S F, et al.GARCIA GARCIA, J. See MARSTON, A, CLARKE, J M F, et al.GASBARRINI, G. See BERNARDIM M, SANTINI, C, et al.

See CORAZZA, G R, TABACCHI, P, et al.Gastrectomy, partial, serum pepsinogens I and II and gastric

mucosal histology after, 1179, regulation of vitamin D and calcium metabolism after, 252

Gastric acid and gastrin responses during intragastric titration innormal subjects and duodenal ulcer patients with G-cell hyper-function, 232- and pancreatic polypeptide responses to modified sham

feeding in duodenal ulcer and increased basal vagal tone in somepatients, 776-, pepsin and electrolytes, basal, sham feed- and pentagas-

trin-stimulated, after omeprazole 20 mg and 40 mg daily, 1018and intrinsic factor, secretion of, effect of

omeprazole, 594secretion and duodenogastric reflux, effect of cimetidine,

766and gastrin production in short bowel syndrome,

914- - release, effect of L-dopa with andwithout inhibition of extracerebral dopa decarboxylase, 1014

and pancreatic endocrine secretion in man,somatostatin as humoral regulator of, 445

basal and pentagastrin, histamine, and bethanecolstimulated, inhibiton by calcitonin gene related peptide, 550

in typhoid fever, 491; (Letters), 1387inhibition of, and gastric carcinoids (Leading

article), 1279

1398

General index

, postprandial and nocturnal, reduction of, duodenalulcer healing by separate cimetidine regimens for, differences inpathophysiology in, 1038

serum pepsinogen I concentrations and cigarettesmoking in duodenal ulcer, 1327

somatostatin inhibition of, after gastric mucosalprostaglandin synthesis inhibition by indomethacin, 1189

carcinoid tumours and inhibition of gastric acid secretion(Leading article), 1279

, association with long lasting unsurmountablehistamine H2 blockade with loxtidine in rat, 1284

carcinoma risk, incomplete sulphomucin-secreting and othertypes of intestinal metaplasia as indicators of, prospective3-centre study, 1319

emptying and motility, assessment of, epigastric impedance asnon-invasive method for, 607

in dyspepsia, measurement of, and effect of cisapride,352

of solids in normal subjects, relationship to gall bladderemptying, 342

, solid and liquid, changes in duodenal ulcer disease, 689juice, bile acid concentrations in erosive oesophagitis, 495luminal prostaglandin E2, reduction by cigarette smoking,

1192-mucosal damage in rat induced by aspirin and taurocholate,

effect of cimetidine and omeprazole, 770- in sepsis, effects of pretreatment with misoprostol,

1025histology and serum pepsinogens I and II after partial

gastrectomy, 1179prostaglandin synthesis inhibition by indomethacin,

somatostatin inhibition of gastric acid secretion after, 1189ulcer, chronic, aetiology of, environmental factors in, case

control study of exposure variables before first symptoms, 789, symptomatic, recurrence of, 2-year comparison between

Caved-S and cimetidine maintenance therapy for prevention of,599; (Erratum), 984- -, treatment by ranitidine alone and by ranitidine plus

Caved-S, comparative study (Clinical trial), 1377See also Intragastric

Gastrin and acid responses during intragastric titration in normalsubjects and duodenal ulcer patients with G-cell hyperfunction,232

and ACTH, neuroendocrine islet cell tumour producing, incalcifying chronic pancreatitis (Case report), 426

, motilin and pancreatic polypeptide concentrations, circulat-ing, correlation with symptoms in functional bowel disorders,1059

-production and gastric acid secretion in short bowel syn-drome, 914

sensitivity in duodenal ulcer, 485somatostatin and insulin, postprandial plasma levels, auto-

nomic regulation of, 683Gastritis inflammatory, or congestive gastropathy in portal

hypertension, 1226Gastroduodenal mucosa, human, actual histamine levels in, mea-

surement for clinical trials on peptic ulcer pathogenesis andvagotomy, sample taking problems in, 1165

Gastroenterology, development and effects of technology in, 1088Gastrointestinal and anorectal disorders in homosexual men

(Leading article), 869disease, exhaled breath hydrogen measurements during

investigation of, extra intestinal influences on, 1349endoscopy, upper, biopsy forceps designed for, comparison of

weight, depth, and diagnostic adequacy of specimens obtainedwith 16 different types, 227

haemorrhage, acute, electrohydrothermoprobe as alternativeto laser therapy in, results of trial, 477

, conservative treatment of, 481; (Letter), 1097; (Letter),1272

upper, drug trial problems in (Leading article), 217-, massive, somatostatin in treatment of, trial of, 221

mucosa, rat, bismuth uptake and subcellular localisation aftershort term administration of colloidal bismuth subcitrate 364

pH, plastic pH electrodes for measurement of, 203symptoms, specific food intolerance as cause of, 164;

(Letters), 980tract lymphoid tissue associated with, morphological and

immunocytochemical study in appendix, 672pathology in Salmonella typhimurium food poisoning,

935surgery, gall bladder sludge formation during prolonged

fasting after, 734, upper, vascular anomalies of, endoscopic laser treat-

ment of, 1338, vascular malformations of, treatment by Neodymium

Yag laser photocoagulation, long term results of, 586Gastrokinetic agents. See CisaprideGastro-oesophageal reflux. See Reflux, gastro-oesophagealGastropathy, congestive, or inflammatory gastritis in portal

hypertension, 1226GAZZARD, B. See FILIPE, M I, POTET, F, et al.GEBOES, K. See RUTGEERTS, P, VAN GOMPEL, F, et al.

GELB, A M. See NOVICK, D M, ENLOW, R w, et al.Genetic influences on splenic function in coeliac disease, 1004

GEORGE, C F. See ARTHUR, M J P, TANNER, A R, et al.GERTSCH, P. See DAWSON, J, GERTSCH, P, et al.GHATEI, M A. See MIAZZA, B M, AL-MUKHTAR, M Y T, et al.

See SAGOR, G R, GHATEI, M A, et al.See SAVAGE, A P, GORNACZ, G E, et al.

GIBSON, P R, HERMANOWICZ, A, VERHAAR, H J J, FERGUSON, D J P,BERNAL, A L, and JEWELL, D P: Isolation of intestinal mononuclearcells: factors released which affect lymphocyte viability andfunction, 60

GILINSKY, N H, DEL FAVERO, G, COT-rON, P B, and LEES, W R:

Congenital short pancreas: a report of two cases (Case reports),304

, MEE, A S, BEATTY, D W, NOVIS, B H, YOUNG, G, PRICE, S, PURVES,L R, and MARKS, I N: Plasma cell infiltration of the small bowel:lack of evidence for a non-secretory form of alpha-heavy chaindisease 928

See also MEE, A S, GIRDWOOD, A H, et al.GILLESPIE, I E: Intestinal ischaemia (Leading article), 653GIMSON, A E. See WESTABY, D, MELIA, w M, et al.GIONCHETTI, P. See CAMPIERI, M, LANFRANCHI, G A, et al.

GIRDWOOD, A H. See MEE, A S, GIRDWOOD, A H, et al.Gliadin, antibodies to, detected by immunofluorescence andmicro-ELISA method, value as markers of active childhood andadult coeliac disease, 667

Glucose perfusion of colon, hyperenteroglucagonaemia and smallintestinal mucosal growth in rats after, 518

Glutathione S-transferase, plasma measurements after paraceta-mol overdose as evidence for early hepatocellular damage, 26

Gluten challenge, acute, in treated adult coeliac disease, morpho-metric and enzymatic study, 169

Glyceryltrinitrate application, intravascular oesophageal varicealpressure assessed by endoscopic fine needle puncture after, 525

, effect on sphincter of Oddi motility and baseline pressure 194Glycosidases, faecal, mucus-degrading, in ulcerative colitis and

Crohn's disease 761GODER, K. See STALNIKOWICZ, R, GODER, K, et al.GOEPEL, J. See MCCORMACK, T T, SIMS, J, et al.GOETING, N, TROTTER, G A, COOKE, T, KIRKHAM, N, and TAYLOR, I:

Effect of warfarin on cell kinetics, epithelial morphology andtumour incidence in induced colorectal cancer in the rat, 807

GOLDFAIN, D. See FILIPE, M 1, POTET, F, et al.GONIS, G. See TZIPORI, S, ROBINS-BROWNE, R M, et al.

GOODALL, A. See SCOTT, B B, GOODALL, A, et al.GOODALL, A H. See WIDEMANN, K H, TREJDOSIEWICZ, L K, et al.

GOODLAD, R A. See SAVAGE, A P, GORNACZ, G E, et al.

1399

General index

GOODMAN, A J, NEOPTOLEMOS, J P, CARR-LOCKE, D L, FINLAY, D B L,

and FOSSARD, D P: Detection of gall stones after acute pancreati-tis, 125

GORNACZ, G E. See SAVAGE, A P, GORNACZ, G E, et al.

GOVINDARAJAN, S. See DE COCK, K M, GOVINDARAJAN, s, et al.

GOYAL, B M. See NIGAM, P, GUPTA, A K, et al.GRADE, A C. See SMOUT, A J P M, BOGAARD, i w, et al.GRAIL, A, and NORVAL M: Elution of cytomegalovirus antibodies fron

adenocarcinoma of the colon, 1053Granulocytes autologous, "'In-labelled, in detection of inflamma-

tory bowel disease, 955, migration to diseased bowel in Crohn's disease, in vivo

assessment of, 378Granulomatous involvement of liver in AIDS, 1220GRETEN, H. See SCHMIEGEL, W H, KREIKER, C, et al.

GRIBBLE, R J N. See THOMPSON, I N, BARR, J A, et al.

GRIMBLE, G K. See KEOHANE, P P, GRIMBLE, G K, et al.

GRIME, J S. See BAXTER, J N, GRIME, J s, et al.GRISCELLI, C. See CERF-BENSUSSAN, N, GUY-GRAND, D, et al.

GRISENDI, A. See BELLENTANI, S, GRISENDI, A, et al.

GULLO, L: Secretin and pancreatic enzyme secretion (Letter), 321GUPTA, A K. See NIGAM, P, GUPTA, A K, et al.Gut. See Gastrointestinal tractGut referees, 106; Erratum, 540GUTMAN, M. See BAR-MEIR, S, HALPERN, z, et al.GUY-GRAND, D. See CERF-BENSUSSAN, N, GUY-GRAND, D, et al.

GUZMAN, S, NERVI, F, LLANOS, 0, LE6N, P, and VALDIVIESO, V:

Impaired lipid clearance in patients with previous acute pan-

creatitis, 888GYDE, S N. See FABRICIUS, P J, GYDE, S N, et al.GYR, K. See BEGLINGER, C, KOHLER, E, et al.

Haemodialysis in 2 patients with hepatorenal syndrome (Casereports), 208

Haemolytic-uraemic syndrome, cholestatic jaundice in (Case re-

port), 315Haemorrhage, gastrointestinal. See Gastrointestinal haemorrhageHAGLUND, U. See ARVIDSSON, S, FALT, K, et al.HAHN, G. See KELLER, F, WAGNER, K, et al.HALPERN, Z. See BAR-MEIR, S, HALPERN, z, et al.HAMER, I D. See RHODES, J M, MARSHALL, T, et al.HAMILTON I, COBDEN, I, and AXON, A T R: In vitro determination of

small intestinal permeability (Letter), 322See also DICKINSON, R J, O'CONNOR, H I, et al.See also WINSTANLEY, P A, ELLIS, W R, et al.

HAMILTON, M I R. See MULLOCK, B M, SHAW, L I, et al.

HARCOURT, R A. See POYNTER, D, PICK, C R, et al.HARKONEN, M. See PAIMELA, H, HARKONEN, M, et al.

HARMAN, I W. See POYNTER, D, PICK, C R, et al.HARPER, P H, LEE, E C G, KETTLEWELL, M G W, BENNETT, M K, and

JEWELL, D P: Role of the faecal stream in the maintenance ofCrohn's colitis, 279

HARRIES, A D, BROWN, R, HEATLEY, R V, WILLIAMS, L A, WOODHEAD, S,and RHODES, J: Vitamin D status in Crohn's disease: associationwith nutrition and disease activity, 1197

HATFIELD, A R W. See SHORVON, P J, COITON, P B, et al.

HAUBRICH, w S: Duodenal ulcers that will not heal (Letter), 105HAVELKA, J. See MARATKA, Z, NEDBAL, j, et al.HAWKEY, C J. See WALT, R P, REYNOLDS, J R, et al.HAYES, J. See TZIPORI, S, ROBINS-BROWNE, R M, et al.

HAYES, I D. See BECKETT, G J, CHAPMAN, B j, et al.HEATLEY, R V. See HARRIES, A D, BROWN, R, et al.HEATON, K w: Diet and diverticulosis-new leads (Leading article),

541

HEGARTY, J E. See MORIARTY, K J, HEGARTY, J E, et al.

See WESTABY, D, MELIA, W M, et al.HEMINGWAY, A P. See JEFFREE, M A, BARTER, S j, et al.

HENDL, J. See MARATKA, Z, NEDBAL, J, et al.HENDRIKSEN, C. See BINDER, V, HENDRIKSEN, c, et al.

HENRY, M M. See SNOOKS, S J, HENRY, M M, et al.Hepatic artery aneurysm, diagnosis and management of, CAT

scanning in (Case report), 752encephalopathy, chronic, lactitol compared with lactulose in

treatment of (Clinical trial), 415veno-occlusive disease induced by herbal tea. quantification

of toxic alkaloid exposure in adults with (Case reports), 101See also Liver

Hepatitis B surface antigen carrier, natural history of (Progressreport), 848- virus infection, chronic. adenine arabinoside 5'-

monophosphate in (Clinical trial), 745chronic active, effect of (+)-cyanidanol-3 (Clinical trial), 975delta, acute, without circulating HBsAg (Case report), 212fulminant, induced by ketoconazole (Case reports), 636non-A, non-B, fulminant, acute, leading to chronic active

hepatitis after cryoprecipitate treatment (Case report), 639, viral, acute, peripheral blood mononuclear and regulatory T

cells in, 739Hepatocellular damage, early, plasma glutathione S-transferascmeasurements after paracetamol overdose as evidence for. 26

in acute alcoholic liver disease. acetaldehyde as initiatorof, 1065

Hepatocyte injury, antibody-mediated, in methyl dopa inducedhepatotoxicity, 1233

Hepatorenal syndrome, haemodialysis in 2 paticnts with (Casereports), 208

Hepatotoxicity induced by methyl dopa, antibody-mediated hepa-tocyte injury in, 1233

HERMANOWICZ, A. See GIBSON, P R, HERMANOWICZ A. et al.

Heroin, parenteral, and alcohol, abuse of, in young adults,association of hepatic cirrhosis with (Leading article). 8

HERRERO-BEAUMONT, G. See CASTANEDA SANZ, S, HERRERO-BEAUMONT, G, et al.

HERVi, M A. See BRAILLON, A, CAPRON, J P, et al.HEI'ZEL, D J. See MADDERN, G J, HOROWITZ, M. et al.

HILL, I D: Statistical tests for 2x2 tables (Letter), 1096HILLIER, K, SMITH, C L, JEWELL, R, ARTHUR. M J P, and ROSS, G:

Duodenal mucosa synthesis of prostaglandins in duodenal ulcerdisease, 237

HIMMELMANN, G W. See SCHMI'I'Z-MOORMANN, P, HIMMELMANN, G W,et al.

Hindgut. See Intestine, largeHINTON, R H. See MULLOCK, B M, SHAW, L j, et al.Hirschsprung's disease, histochemical diagnosis of, clinical cvalua-

tion, 393Histamine, actual levels in human gastroduodenal mucosa. mea-

surement for clinical trials on peptic ulcer pathogcnesis andvagotomy, sample taking problems in, 1165

and pathogenesis of duodenal ulcer (Leading article), 1159H2 blockade, unsurmountable, long lasting, with loxtidine,

association with gastric carcinoid tumours in rat, 1284HLA phenotype and ulcerative colitis, 952HLA-DR antigens not associated with susceptibility to primary

biliary cirrhosis, 625HOBSLEY, M. See MELVILLE, R J, SULEIMAN, s I. et al.

HODGSON, H J F. See ADEYEMI, E 0. NEUMANN, S, et al.See SAVERYMUTTU, S H, HODGSON, H J F, et al.See SAVERYMU'I'U, S H, PETERS, A M, et al.

HODGSON, J. See MAYER, A D, AIREY, M, et al.HOLBOROW, E J. See UNSWORTH, D j, and HOLBOROW, E J

HOLGATE, A M. See READ, N W, AL-JANABI, M N, et al.HOLST, J J. See LOUD, F B, HOLST, J j, et al.Homosexual men, gastrointestinal and anorectal disorders in

(Leading article), 869HOROWITZ, M. See MADDERN, G J, HOROWITZ, M, et al.

HORTNAGL, H. See LENZ, K, DRUML, w, et al.HOWDEN, c w, and HUNT, R H: Gastric secretion in patients with

typhoid (Letter), 1387HUI, W-M. See LAM, S-K. LAI, C-L, et al.

1400

General index

HULL, D H, and BEALE. P J: Cigarette smoking and duodenal ulcer,1333

HUNT, R H. See HOWDEN, C w, and HUNT, R HHUNT, T M. See MULLOCK, B M, SHAW, L J, et al.Hydrogen breath test. See Lactulose hydrogen breath test

in exhaled breath, measurements during investigation ofgastrointestinal disease, extra intestinal influences oni, 1349

profile in breath after solid meal containing unabsorbablecarbohydrate, interpretation of, 834

Hyperenteroglucagonaemia and small intestinal mucosal growthafter colonic perfusion of glucose in rats, 518

Hypertension, portal, and cirrhosis, propranolol pharmacology in,14

inflammatory gastritis or congestive gastropathy in,1226

IHRE, T. See MAGNUSSON, 1, IHRE, T, et al.Ileum, carcinoid tumour of, bleeding, endoscopic diagnosis of

(Letter), 431, rabbit, in vitro, and rat jejunum in vivo, solute and water

transport in, alteration by topical methotrexate, 704-, rat, permeability to macromolecules increased by lysophos-

phatidylcholine, 369Imerslund-Grasbeck syndrome, absent ileal uptake of IF-bound

vitamin B12 in vivo in (Case report), 311Immune deficiency syndrome, acquired. See AIDSImmunofluorescence and micro-ELISA method, antibodies to

gliadin detected by, value as markers of active childhood andadult coeliac disease, 667

Immunoglobulins, platelet-associated, as cause of thrombocyto-penia in primary biliary cirrhosis, 1074

Incontinence, anorectal, and rectal prolapse, innervation to pubo-rectalis and external anal sphincter muscles in, 470

"'Indium autologous granulocytes in detection of inflammatorybowel disease, 955

Indomethacin inhibition of gastric mucosal prostaglandin synthesis,somatostatin inhibition of gastric acid secretion after, 1189

Injection pressure and volume, effect on pancreas, and pathogene-sis of acute gall stone pancreatitis, 615

Insulin, somatostatin, and gastrin, postprandial plasma levels,autonomic regulation of, 683

Intestinal ischaemia (Leading article), 653lymphangiectasia and chylous ascites in 'yellow-nail' syn-

drome (Case report), 1266, impaired splenic function in, development of (Case

report), 861pseudo-obstruction, coeliac disease presenting with (Letter),

538; (Letter), 758Intestine, large, polyps and diverticula of, necropsy survey in HongKong, 1045

, rabbit, acetate absorption and metabolism in, 562small, mucosa of, in young, adult, and old rats submitted to

protein deficiency and rehabilitation, morphometric study of,816

mucosal growth, and hyperenteroglucagonaemia aftercolonic perfusion of glucose in rats, 518,-, permeability, in vitro determination in coeliac disease

(Letters), 322plasma cell infiltration of, no evidence for non-

secretory alpha-heavy chain disease in, 928resection in rat, raised plasma peptide YY after,

responsible for trophic response?, 1353Intestines, function and blood supply, 20-year surgical study, 656

, functional disorders, correlation between symptoms andcirculating motilin, pancreatic polypeptide and gastrin concen-trations in, 1059-, human, intraepithelial lymphocytes of, isolation, character-

isation and natural killer activity, 81, inflamed, in Crohn's disease, granulocyte migration to, in

vivo assessment of, 378-, inflammatory disease, chronic, in childhood, histological

diagnosis of, 55circulating human leucocyte elastase in, 1306desialation and desulphation of rectal mucus by

faecal extracts in, histochemical demonstration of, 1312detection of, "'Indium autologous granulocytes

in, 955faecal sulphatase in, 466

leucocyte (2'-5') oligo adenylate synthetaseactivity in, 556-, Kaposi's sarcoma of, presenting as apparent ulcerative colitis(Case report), 295

, metaplasia, incomplete sulphomucin-secreting and othertypes of, as indicators of gastric cancer risk, prospective 3-centrestudy, 1319-, rnononuclear cells, isolation of, release of factors affecting

lymphocyte viability and function during, 60, permeability in coeliac disease and dermatitis herpetiformis,

1214to 5'Cr-EDTA in rats with experimental enteropathy,

579protein absorption in normal man, influence of protein

composition and hydrolysis method, 907, resection, plasma enteroglucagon and cell proliferation in rat

after, influence of somatostatin and bombesin, 89, responsc to cholera toxin, prostaglandins not mediators of,

680, short bowel syndrome, gastric acid secretion and gastrin

production in, 914Intragastric acidity, effect of pirenzepine in healthy volunteers,

evaluation with 24-hour intragastric pH-monitoring, 241pH, rapid rise produced by intravenous omeprazole, 902

Intrinsic factor, gastric acid and pepsin, secretion of, effect ofomeprazole, 594

ISAACSON, P G. See SPENCER, J, FINN, T, et al.ISLAM, M R: Citrate in oral rehydration therapy (Letter), 429Islet cell tumour, neuroendocrine, producing gastrin and ACTH in

calcifying chronic pancreatitis (Case report), 426Isosorbide dinitrate, response of endoscopic variceal pressuremeasurements to, 843

IYER, S K. See ORENSTEIN. M S, TAVITIAN, A, et al.

JACOBSON, S, and PLANTIN, L-O: Concentration of selenium inplasma and erythrocytes during total parenteral nutrition inCrohn's disease, 50

JAMES, 0 F w: D-penicillamine for primary biliary cirrhosis (Leadingarticle), 109

See also BASSENDINE, M F, COLLINS, J D, et al.See also BASSENDINE, M F, DEWAR, P J, et al.

JAMIESON, G G. See MADDERN, G J, HOROWITZ, M, et al.Jaundice, cholestatic, in haemolytic-uraemic syndrome (Case

report), 315-, computer-aided selection of diagnostic tests in patients with,

961JEFFREE, M A, BARTER, S J, HEMINGWAY, A P, and NOLAN, D J:

Endoscopic diagnosis of a bleeding ileal carcinoid tumour(Letter), 431

JEFFREY G, KIBBLER, C C, BAILLOD, R, FARRINGTON, K, and MORGAN,M Y: Cholestatic jaundice in the haemolytic-uraemic syndrome(Case report), 315

Jejunum, human, fluid secretion, inhibition by nufenoxole, 75, mechanism of action of dioctyl sodium sulphosuccinate

in, 1008prostaglandin E. concentrations, increase in acute cholera,

188, rat, in vivo and rabbit ileum in vitro, solute and water

transport in, alteration by topical methotrexate, 704JENKINS, D. See SCOYT, B B, GOODALL, A, et al.

1401

General index

JENKINS, W J. See BURMAN, J F, JENKINS, W J, et al.JENKINSON, L R, NORRIS, T L, and WATSON, A: Combined manometry

and antimony pH catheter (Letter), 1271JESSEN, K. See SCHMIEGEL, W H, KREIKER, C, et al.JEWELL, D P. See COTrrONE, M, BUNCE, M, et al.

See GIBSON, P R, HERMANOWICZ, A, et al.See HARPER, P H, LEE, E C G, et al.

JEWELL, R. See HILLIER, K, SMITH, C L, et al.JIAN, R, DUCROT, F, PIEDELOUP, C, MARY, J Y, NAJEAN, Y, and BERNIER,

J J: Measurement of gastric emptying in dyspeptic patients: effectof a new gastrokinetic agent (cisapride), 352

JOHANSSON, C. See MAGNUSSON, 1, IHRE, T, et al.JOHNSON, A G. See MCCORMACK, T T, SIMS, J, et al.JOHNSON, P J. See KEATING, J J, JOHNSON, R D, et al.JOHNSON, R D. See KEATING, J J, JOHNSON, R D, et al.JOHNSTON, D. See DICKINSON, R J, O'CONNOR, H J, et al.JONES, D B: Propranolol disposition in cirrhosis (Letter), 865-, and YEOMANS, N D: Cimetidine versus ranitidine in short term

healing of duodenal ulcers (Letter), 642JOSHI, L D. See NIGAM, P, GUPTA, A K, et al.

KAKAVOULIS, T. See EARLAM, R J, AMERIGO, J, et al.KALIS, B. See BERCOFF, E, BERNUAU J, et al.KALTHOFF, H. See SCHMIEGEL, W H, KREIKER, C, et al.KAPETANAKIS, A. See MANOUSOS, 0, DAY, N E, et al.KAPOOR, K K. See NIGAM, P, GUPTA, A K, et al.Kaposi's sarcoma of bowel presenting as apparent ulcerative colitis

(Case report), 295KARAYIANNIS, P. See LEE, C A, KERNOFF, P B A, et al.

See WELLER, I V D, LOK, A S F, et al.KARMELI, F. See STALNIKOWICZ, R, GODER, K, et al.KARONEN, S-L. See PAIMELA, H, HARKONEN, M, et al.KAUFFMAN, G L, JR, See MOGARD, M H, MAXWELL, v, et al.KEATING, J J, JOHNSON, R D, JOHNSON, P J, and WILLIAMS, R: Clinical

course of cirrhosis in young adults and therapeutic potential ofliver transplantation, 1359

KEIGHLEY, M R B. See FABRICIUS, P J, GYDE, S N, et al.KELLER, F, WAGNER, K, LENZ, T, POMMER, W, HAHN, G, MOLZAHN, M,

and KRAUSE, P-H: Haemodialysis in 'hepatorenal syndrome':report on two cases (Case reports), 208

KELLY, M J. See MORIARTY, K J, HEGARTY, J E, et al.See MORIARTY, K J, KELLY, M J, et al.See MORIARrY, K J, ROLSTON, D D K, et al.

KENNA, G. See NEUBERGER, J, KENNA, G, et al.KENNEDY, H. See MCCORMACK, T T, SIMS, J, et al.KENNEDY, J F. See RHODES, J M, GALLIMORE, R, et al.KEOHANE, P P, GRIMBLE, G K, BROWN, B, SPILLER, R C, and SILK, D B A:

Influence of protein composition and hydrolysis method on

intestinal absorption of protein in man, 907KERNOFF, P B A. See LEE, C A, KERNOFF, P B A, et al.Ketoconazole, fulminant hepatitis induced by (Case reports), 636KETrLEWELL, M G W. See HARPER, P H, LEE, E C G, et al.KIBBLER, C C, COHEN, D L, CRUICSHANK, J K, KUSHWAHA, S S, MORGAN,M Y, and DICK, R D: Use of CAT scanning in the diagnosis andmanagement of hepatic artery aneurysm (Case report), 752

See also JEFFREY, G, KIBBLER, C C, et al.KING, R F G J. See WILLIAMS, N S, EVANS, P, et al.KINGHAM, J G C, and DAWSON, A M: Origin of chronic right upper

quadrant pain, 783KINSMAN, R 1. See READ, N W, AL-JANABI, M N, et al.KIRKEGAARD, P. See SKOV OLSEN, P, POULSEN, S S, et al.KIRKHAM, N. See GOETING, N, TROTrER, G A, et al.

See TROTTER, G A, MORGAN, G R, et al.KIRUBAKARAN, C. See ROBB, T A, DAVIDSON, G P, et al.KITCHINGMAN, G. See WALT, R P, REYNOLDS, J R, et al.KlWrANG, E, AADLAND, E, and SCHJ0NSBY, H: Effect of omeprazoleon the secretion of intrinsic factor, gastric acid and pepsin inman, 594

KLEINBERGER, G. See LENZ, K, DRUML, W, et al.

KO, W. See KUMANA, C R, NG, M, et al.KOCIANOVAk, J. See MARATKA, Z, NEDBAL, J, et al.KOHLER, E. See BEGLINGER, C, KOHLER, E, et al.KOHN, A, ANNIBALE, B, SURIANO, G, SEVERI, C, SPINEI.LA, s, and DELLE

FAVE, G: Gastric acid and pancreatic polypeptide responses tomodified sham feeding; indication of an increased basal vagaltone in a subgroup of duodenal ulcer patients, 776

KONDO, M. See NISHIDA, K, SUGIURA, M, et al.KOO, J. See LAM, S-K, and KOO, J.

KOTrLER, R E. See MEE, A S, GIRDWOOD, A H, et al.KOVACS, T. See MOGARD, M H, MAXWELL, V, et al.KRAENZLIN, M E. See WOOD, S M, KRAENZLIN, M E, et al.KRANZ, V. See BANK, S. ZIMMERMAN, H, et al.KRAUSE, P-H. See KELLER, F, WAGNER, K, et al.KREEK, M J. See NOVICK, D M, ENLOW, R W, et al.KREIKER, C. See SCHMIEGEL, W H, KREIKER, C, et al.KREINER, S. See BINDER, V, HENDRIKSEN, C, et al.KUCHARZ, E J: Inhibitors of collagenolytic enzymes in the serum of

patients with chronic liver disorders, 1364KUDRMANN, J. See MAAATKA, Z, NEDBAL, J, et al.KUMANA, C R, NG, M, LIN, H J, KO, W, WU, P-C, and TODD, D: Herbal

tea induced hepatic veno-occlusive disease: quantification oftoxic alkaloid exposure in adults (Case reports), 101

KUSHWAHA, S S. See KIBBLER, C C, COHEN, D L, et al.

LAB6, G. See BOLONDI, L, GAIANI, S, et al.-. See CAMPIERI, M, LANFRANCHI, G A, et al.Lactitol in treatment of chronic hepatic encephalopathy, compari-

son with lactulose (Clinical trial), 415Lactulose hydrogen breath test in evaluation of effect of loper-amide and naloxone on mouth-to-caecum transit time, 700

LAGGNER, A. See LENZ, K, DRUML, W, et al.LAGHI, V. See BARNABA, V, TAMBURRINI, E, et al.LAI, C-L. See LAM, S-K, LAI, C-I, et al.LAM, S-K, and KOO, J: Gastrin sensitivity in duodenal ulcer, 485

, LAI, C-L, NG, M, FOK, K-H, and HUI, W-M: Duodenal ulcerhealing by separate reduction of postprandial and nocturnal acidsecretions have different pathophysiology, 1038

LANFRANCHI, G A. See CAMPIERI, M, LANFRANCHI, G A, et al.LANGMAN, M J S: Upper gastrointestinal bleeding: the trials of trials

(Leading article), 217, MCCONNELL, T H, SPIEGELIHALTER, D J, and MCCONNELL, R B:

Changing patterns of coeliac disease frequency: an analysis ofCoeliac Society membership records, 175

See also WALT, R P, REYNOLDS, J R, et al.LANTHIER, P L, and MORGAN, M Y: Lactitol in the treatment of

chronic hepatic encephalopathy: an open comparison withlactulose (Clinical trial), 415

LARSEN, N-E. See ANDERSEN, B N, LARSEN, N-E. et al.Laser photocoagulation, Neodymium Yag. in treatment of vascular

malformations of gastrointestinal tract, long term results of, 586treatment, endoscopic, of vascular anomalies of upper

gastrointestinal tract, 1338LAVENDER, J P. See SAVERYMUTTIU, S H, PETERS, A M, et al.LAVERGNE, A. See MODIGLIANI, R, BORIES, C, et al.LAWSON, J 0 N. See BARR, L C, BOOIH, J, et al.LAZZARI, R. See VOLTA, U, LENZI, M, et al.LAZZARONI, M. See PARENTE, F, LAZZARONI, M, et al.LE CHARPENTIER, Y. See MODIGLIANI, R, BORIES, C, et al.LEDGER, J E, WATSON, G J, AINLEY, C C, and COMPSTON, J E: Biliary

excretion of radioactivity after intravenous administration of3H-1,25-dihydroxyvitamin D3 in man, 1240

LEE, C A, KERNOFF, P B A, KARAYIANNIS, P, and I-HOMAS, H C: Acute

fulminant non-A, non-B hepatitis leading to chronic activehepatitis after treatment with cryoprecipitate (Case report), 639

LEE, E C G. See HARPER, P H, LEE, E C G, et al.LEE, F I, and COSTELLO, F T: Crohn's disease in Blackpool-

incidence and prevalence 1968-80, 274LEES, W R. See GILINSKY, N H, DEL FAVERO, G, et al.

1402

General index

LEISS, O, and VON BERGMANN, K: Effect of Rowachol on biliary lipidsecretion and serum lipids in normal volunteers, 32

LEMAIRE, A. See BERCOFF, E, BERNUAU, J, et al.LE MINOR, M. See SAINT-MARC GIRARDIN, M-F, LE MINOR, M, et al.

LENNARD-JONES, J E. See BARNES, P R H, and LENNARD-JONES, J E

. See MCINTYRE, P B, MACRAE, F A, et al.See PRESTON, D M, ADRIAN, T E, et al.

LENZ, H J, MORTRUD, M T, RIVIER, J E, and BROWN, M R: Calcitoningene related peptide inhibits basal, pentagastrin, histamine, andbethanecol stimulated gastric acid secretion, 550

LENZ, K, DRUML, W, KLEINBERGER, G, HORTNAGL, H, LAGGNER, A,

SCHNEEWEISS, B, and DEUTSCH, E: Enhancement of renal functionwith ornipressin in a patient with decompensated cirrhosis (Casereport), 1385

LENZ, T. See KELLER, F, WAGNER, K, et al.LENZI, M. See VOLTA, U, LENZI, M, et al.LE6N, P. See GUZMAN, S, NERVI, F, et al.Leucocyte elastase, human, circulating, in inflammatory bowel

disease, 1306Leucocytes, (2'-5') oligo adenylate synthetase activity in inflamma-

tory bowel disease, 556LEVENSTEIN, S, PRANTERA, C, LUZI, C, and D'UBALDI, A: Low residue

or normal diet in Crohn's disease: a prospective controlled studyin Italian patients, 989

LEVI, A J: Diet in the management of Crohn's disease (Leadingarticle), 985

. See also BJARNASON, 1, MARSH, M N, et al.See also BJARNASON, 1, SMETHURST, P, et al.

LEVI, J. See PRICE, A B, LEVI, J, et al.LEVRERO, M. See BARNABA, V, TAMBURRINI, E, et al.

LIGABUE, A. See BERNARDI, M, SANTINI, C, et al.LIN, H J. See KUMANA, C R, NG, M, et al.LINDEMAN, J. See VAN SPREEUWEL, J P, DUURSMA, G C, et al.

LINTOTT, D J. See WINSTANLEY, P A, ELLIS, W R, et al.

Lipid clearance, impairment in patients with previous acutepancreatitis, 888

Lipids, biliary secretion and serum concentrations, effect ofRowachol in normal volunteers, 32

Lipoprotein, liver-specific, antigenic composition of, analysis withmurine monoclonal antibodies, 510

Liver abscess, amoebic, cholestasis in, 140cell. See Hepatocytecirrhosis in young adults, association with alcohol and

parenteral heroin abuse (Leading article), 8disease, alcoholic, acute, acetaldehyde as initiator of hepa-

tocellular damage in, 1065, chronic, collagenolytic enzyme inhibitors in serum in,

1364granulomatous involvement in AIDS, 1220in obesity, 133; (Letter), 1096transplantation, therapeutic potential of, and clinical course

of disease, in cirrhosis in young adults, 1359See also Hepatic

Liver-specific lipoprotein, antigenic composition of, analysis withmurine monoclonal antibodies, 510

LLANOS, O. See GUZMAN, S, NERVI, F, et al.LOIZEAU, E. See ETIENNE, A, FIMMEL, C J, et al.LOK, A S F. See WELLER, I V D, LOK, A S F, et al.LONGANESI, A. See BALDI, F, FERRARINI, F, et al.

Loperamide and naloxone, effect on mouth-to-caecum transit timeevaluated by lactulose hydrogen breath test, 700

LORENZ, W. See THON, K P, LORENZ, w, et al.LORENZ-MEYER, H. See SCHMITZ-MOORMANN, P, HIMMELMANN, G W, et

al.LOSOWSKY, M S. See FOSTER, P N, BULLEN, A w, et al.

LOUD, F B, HOLST, J J, EGENSE, E, PETERSEN, B, and CHRISTIANSEN, J:Is somatostatin a humoral regulator of the endocrine pancreasand gastric acid secretion in man?, 445

LOVE, A H G. See COLLINS, B J, CROTHERS, G, et al

See SPENCE, R A J, COLLINS, B J, et al.

Loxtidine, long lasting unsurmountable histamine H2 blockadewith, association with gastric carcinoid tumours in rat, 1284

LUCAS, M L. See RAWLINGS, J M, and LUCAS, M L

LUCEY, M R, WASS, J A H, FAIRCLOUGH, P D, WEBB, J, WEBB, S,MEDBAK, s, and REES, L H: Autonomic regulation of postprandialplasma somatostatin, gastrin and insulin, 683

Lupus erythematosus, systemic, protein-losing enteropathy due to(Letters), 757

LUZI, C. See LEVENSTEIN, S, PRANTERA, c, et al.Lymphangiectasia, intestinal, and chylous ascites in 'yellow-nail'syndrome (Case report), 1266

, impaired splenic function in, development of (Casereport), 861

Lymphocytes, intraepithelial, of human intestines, isolation, char-acterisation and natural killer activity, 81

, viability and function, release of factors affecting, duringisolation of intestinal mononuclear cells, 60

Lymphoid tissue associated with gut, morphological and immuno-cytochemical study in appendix, 672

Lysophosphatidylcholine, rat ileal permeability to macromoleculesincreased by, 369

MCADAM, W A F. See MORGAN, A G, PACSOO, C, et al.MCCARTHY, C F. See O'GRADY, J G, STEVENS, F M, et al.

MCCARTNEY, E. See TZIPORI, S, ROBINS-BROWNE, R M, et al.

MCCLELLAND G R, and SUrrON, J A: Epigastric impedance: a

non-invasive method for the assessment of gastric emptying andmotility, 607

MCCONNELL, R B. See LANGMAN, M J S, MCCONNELL, T H, et al.

MCCONNELL, T H. See LANGMAN, M J S, MCCONNELL, T H, et al.

MCCORMACK, T T, SIMS, J, EYRE-BROOK, 1, KENNEDY, H, GOEPEL, J,

JOHNSON, A G, and TRIGER, D R: Gastric lesions in portalhypertension: inflammatory gastritis or congestive gastropathy,1226

MCCREADY, D R, CLARK, L, and COHEN, M M: Cigarette smokingreduces human gastric luminal prostaglandin E2, 1192

MCDONALD, C. See WILSON, J S, BERNSTEIN, L, et al.

MACDOUGALL, B R D. See WESTABY, D, MELIA, W M, et al.

MCFARLAND, R J. See COLLINS, B J, CROTHERS, G, et al.

MCFARLANE, A. See READ, N W, AL-JANABI, M N, et al.

MCGIVAN, J D. See BARRY, R E, and MCGIVAN, J D

MCINNES, I. See RUBINSTEIN, D, MCINNES, I, et al.MCINTOSH, J H, BYTH, K, and PIPER, D w: Environmental factors in

aetiology of chronic gastric ulcer: a case control study ofexposure variables before the first symptoms, 789

MCINTYRE, P B, MACRAE, F A, BERGHOUSE, L, ENGLISH, J, and

LFNNARD-JONES, J E: Therapeutic benefits from a poorly absorbedprednisolone enema in distal colitis, 822

MCKAY, L F, EASTWOOD, M A, and BRYDON, W G: Methane excretion inman-a study of breath, flatus, and faeces, 69; (Letter), 1270

MACKENZIE, J F, CALDER, I, and BENSON, L H: Specific foodintolerance (Letter), 980

See also FARAH, D A, CALDER, I, et al.MCMAHON, M J. See MAYER, A D, AIREY, M, et al.MCNEIL, D. See WILSON, J S, BERNSTEIN, L, et al.MACRAE, F A. See MCINTYRE, P B, MACRAE, F A, et al.Macromolecules, rat ileal permeability to, increased by lysophos-

phatidylcholine, 369MADDERN, G J, HOROWITZ, M, HETZEL, D J, and JAMIESON, G G:

Altered solid and liquid gastric emptying in patients withduodenal ulcer disease, 689

MAEDA, M. See RAINEY, J B, MAEDA, M, et al.MAGNUSSON, 1, IHRE, T, JOHANSSON, C, SELIGSON, U, TORNGREN, S,and UVNAS-MOBERG, K: Randomised double blind trial ofsomatostatin in the treatment of massive upper gastrointestinalhaemorrhage, 221

Malabsorption and diarrhoea in AIDS, 4 cases showing frequencyof unusual protozoan infestations, 179

MALCHOW, H. See SCHMITZ-MOORMANN, P, HIMMELMANN, G w, et al.

1403

General index

MANCINI, M. See CONTALDO, F, MANCINI, M, et al.MANENTI, F. See BELLENTANI, S, GRISENDI, A, et al.MANOUSOS, 0, DAY, N E, TZONOU, A, PAPADIMITRIOU, C, KAPETANAKIS,

A, POLYCHRONOPOULOU-TRICHOPOULOU, A, and TRICHOPOULOS, D:

Diet and other factors in the aetiology of diverticulosis: an

epidemiological study in Greece, 544MARATKA, Z, NEDBAL, J, KOCIANOVA, J, HAVELKA, J, KUDRMANN, J,and HENDL, J: Incidence of colorectal cancer in proctocolitis: a

retrospective study of 959 cases over 40 years, 43MARKS, N. See BOYD, E, and MARKS, I N

- See GILINSKY, N H, MEE, A S, et al.. See MEE, A S, GIRDWOOD, A H, et al.

MARSH, M N. See BJARNASON, 1, MARSH, M N. et al.See DUHRA, P M, QUIGLEY, E M M, et al.

MARSHALL, T. See RHODES J M, MARSHALL, T, et al.MARSTON, A, CLARKE, J M F, GARCIA GARCIA, j, and MILLER, A L:

Intestinal function and intestinal blood supply: a 20 year surgicalstudy, 656

MARTY, J F, VERNAY, M Y, and ABRAVANEL, G M: Acetate absorptionand metabolism in the rabbit hindgut, 562

MARY, J Y. See JIAN, R, DUCROT, F. et al.MASCI, E. See CALDARA, R, BARBIERI, C, et al.MASON, R R. See SHORVON, P J, CO-rrON, P B, et al.MAIHAN M M, and MAIHAN, v i: Rectal mucosal morphologic

abnormalities in normal subjects in southern India: a tropicalcolonopathy?, 710

MATHAN, V 1. See MATHAN, M M, and MATHAN. V

MArIHEWSON, K. See BOWN, S G, SWAIN, C P, et al.MAXWELL, V. See MOGARD, M H, MAXWELL, v, et al.MAYBERRY, J F: Some aspects of the epidemiology of ulcerative

colitis (Progress report), 968MAYER, A D, AIREY, M, HODGSON, j, and MCMAHON. M J: Enzyme

transfer from pancreas to plasma during acute pancreatitis: thecontribution of ascitic fluid and lymphatic drainage of thepancreas, 876

MEDBAK, S. See LUCEY, M R, WASS, J A H, et al.MEE, A S, GIRDWOOD, A H, WALKER, E, GILINSKY, N H, KO-I1lLER, R E,

and MARKS, N: Comparison of the oral (PABA) pancreaticfunction test, the secretin-pancreozymin test and endoscopicretrograde pancreatography in chronic alcohol induced pan-

creatitis, 1257-. See also GILINSKY, N H, MEE, A S, et al.MEIJER, C J L M. See VAN SPREEUWEL, J P, DUURSMA, G C, et al.MELIA, W M. See WESTABY, D, MELIA, W M, et al.MELVILLE, R J, SULEIMAN, S 1, WHITFIELD, P F, PARKIN, J V,

NWABUNIKE, T o, and HOBSLEY, M: Effect of cimetidine on gastricsecretion and duodenogastric reflux, 766

MESSING, B. See MODIGLIANI, R, BORIES, C, et al.Methane excretion, analysis of breath, flatus and faeces for, 69;

(Letters), 1270Methotrexate, topical, alteration of solute and water transport in

rat jejunum in vivo and rabbit ileum in vitro by, 704Methyl dopa, hepatotoxicity induced by, antibody-mediated hepa-

tocyte injury in, 1233Metoprolol, oral, for long term management of variceal bleeding in

cirrhosis, comparison with injection sclerotherapy (Clinicaltrial), 421

METREAU, J-M. See SAINT-MARC GIRARDIN, M-F, LE MINOR, M, et al.See SCEMAMA-CLERGUE J, DOUTFRELLOT-PHILIPPON, C, et al.

MEYER ZUM BUSCHENFELDE, K-M. See STARITZ, M, PORALLA, 'I, et al.MIAZZA, B M, AL-MUKHTAR, M Y T, SALMERON, M, GHAIL-EI, M A,

FELCE-DACHEZ, M, FILALI, A, VILLET, R, WRIGHT, N A, BLOOM, S R,

and RAMBAUD,' J-C: Hyperenteroglucagonaemia and small intes-tinal mucosal growth after colonic perfusion of glucose in rats,

518Micro-ELISA method and immunofluorescence, antibodies to

gliadin detected by, value as markers of active childhood andadult coeliac disease, 667

MIGLIOLI, M. See BALDI, F, FERRARINI, F, et al.MILLA, P J. See PINKERTON, C R, BOOTH, I W, et al.

MILLER, A L. See MARSI'ON, A, CLARKE, J M F, et al.MILLER, D S. See FREEMAN, K, ANt1'HONY, P P, et al.MINDEL, A. See WELLER, V D, LOK, A S F, et al.MINGUZZI, M R. See CAMPIERI, M, LANFRANCHI G A, et al.Misoprostol, pretreatment with, effects on gastric mucosal damage

in sepsis, 1025MODIGLIANI, R, BORIES, C, LE CHARPENTIER, Y, SALMERON, M, MESSING,

B, GALIAN, A, RAMBAUD, J-C, LAVERGNE, A, COCHAND-PRIOLLET, B,and DESPORTES, i: Diarrhoea and malabsorption in acquiredimmune deficiency syndrome: a study of four cases with specialemphasis on opportunistic protozoan infestations, 179

MOGARD, M H, MAXWELL, V, KOVACS, T, VAN DEVENTER, G, ELASHOFF,

J D, YAMADA. T, KAUFFMAN, G L, JR, and WALSH, J H: Somatostatininhibits gastric acid secretion after gastric mucosal prostaglandinsynthesis inhibition by indomethacin in man, 1189

MOLLIN, D L. See BURMAN, J F, JENKINS, W J, et al.MOLZAHN, M See KELLER, F, WAGNER, K, et al.MONACO, G. See PIGNATA, C, IRONCONE, R, et al.MONJARDINO, J. See WELLER, V D. LOK, A S F, et al.Monoclonal antibodies, murine, in analysis of antigenic composi-

tion of liver-specific lipoprotein. 510antibody defining CA 19-9 in pancreatic juices and sera, 456

Mononuclear cell complement receptor blockade in primary biliarycirrhosis, 20

-cells and regulatory T cells in peripheral blood in acute viralhepatitis, 739

, intestinal, isolation of, release of factors affectinglymphocyte viability and function during, 60

MONTENEGRO, M R G. See RODRIGUES, M A M, DE CAMARGO, J L V, et al.MORGAN, A G, PACSOO, C. and MCADAM, W A F: Comparison between

ranitidine and ranitidine plus Caved-S in the treatment of gastriculceration, 1377

- , Maintenance therapy: a two year comparisonbetween Caved-S and cimetidine treatment in the prevention ofsymptomatic gastric ulcer recurrence 599; (Erratum), 984

MORGAN, G R. See TRO-1-I'ER, G A, MORGAN, G R, et al.MORGAN, M Y. See JEFFREY, G, KIBBLER, C C, et al.

See KIBBLER, C C. COHEN, D L, et al.See LANTHIER, P L, and MORGAN, M Y

MORIARTY, K J, HEGARTY, J E, FAIRCLOUGH, P D, KELLY, M J, CLARK,

M L, and DAWSON, A M: Relative nutritional value of wholeprotein, hydrolysed protein and free amino acids in man, 694

, KELLY, M J, BEETHAM, R, and CLARK, M L: Studies on themechanism of action of dioctyl sodium sulphosuccinate in thehuman jejunum, 1008-, ROLS'I'ON, D D K, KELLY, M J, SHIELD. M, and CLARK, M L:

Nufenoxole, a new antidiarrhoeal agent, inhibits fluid secretionin the human jejunum, 75

Morphine, influence on distal oesophagus and lower oesophagealsphincter, manometric study, 802

Morphine-neostigmine, abnormal responses to, in patients withundefined biliary-type pain, 1367

MORRIS, D L: Conservative treatment of gastrointestinal haemor-rhage (Letter), 1097

MORSON, B C. See WHI1-EWAY, J, and MORSON, B C

MORJ0RUD, M T. See LENZ, H J, MORTRUD, M T, et al.MOSIMANN, F. See DAWSON, J, GERTSCH, P, et al.Motilin, pancreatic polypeptide and gastrin concentrations, circu-

lating, correlation with symptoms in functional bowel disorders,1059

Motor activity. interdigestive and postprandial, of distal oesopha-gus. effect of cisapride, 246

oesophageal. at acid reflux and during endogenous acidexposure in healthy subjects and in oesophagitis, 336

Mouth-to-caccum transit time, effect of loperamide and naloxoneevaluated by lactulose hydrogen breath test, 700

Mucosa, gastroduodenal, human, actual histamine levels in,measurement for clinical trials on peptic ulcer pathogenesis andvagotomy, sample taking problems in, 1165-. gastrointestinal, rat, bismuth uptake and subcellular localisa-

1404

General index

tion after short term administration of colloidal bismuth subci-trate, 364

, rectal, morphologic abnormalities in normal subjects insouthern India designated as 'tropical colonopathy', 710

Mucosa(1). See also under Gastric; Intestine, smallMucus, rectal, normal and in inflammatory bowel disease, desiala-

tion and desulphation by faecal extracts, histochemical demon-stration of, 1312

Mucus-degrading faccal glycosidases in ulcerative colitis andCrohn's disease, 761

MUGERWA, J W. See WATTERS, D A K, SMITH, A N, et al.MULLOCK, B M, SHAW, L J, FITZHARRIS, B, PEPPARD, J, HAMILTON,M J R, SIMPSON, M T, HUNT, T M, and HINTON, R H: Sources ofproteins in human bile, 500

MUNRO, A. See WEBER, J N, CARMICHAEL, D J, et al.MURRAY, D J. See STIEL, D, MURRAY, D J, et al.MURRAY-LYON, I M. See ANDERSON, M G, and MURRAY-LYON, I M

NAJEAN, Y. See JIAN, R. DUCROT, F, et al.NALIN, D R: Citrate in oral rehydration therapy (Letter), 429Naloxone and loperamide, effect on mouth-to-caecum transit time

evaluated by lactulose hydrogen breath test, 700NANDA, R. See SARIN. S K, SACHDEVA, G K, et al.NAVONE, C. See FARCI, P, BARBERA, C, et al.NEDBAL, J. See MARATKA, Z, NEDBAL, J, et al.Neodymium Yag laser photocoagulation treatment of vascular

malformations of gastrointestinal tract, long term results of, 586NEOPTOLEMOS, J P. See GOODMAN, A J, NEOPTOLEMOS, J P, et al.Neostigmine. See Morphine-neostigmineNERVI, F. See GUZMAN, S, NERVI, F, et al.NEUBERGER, J, CHRISTENSEN, E, PORTMANN, B, CABALLERIA, J, RODES,

J, RANEK, L, TYGSTRUP, N, and WILLIAMS, R: Double blindcontrolled trial of d-penicillamine in patients with primary biliarycirrhosis, 114

, KENNA, G, NOURI ARIA, K, and WILLIAMS, R: Antibody medi-ated hepatocyte injury in methyl dopa induced hepatotoxicity.1233

See also AL-AGHBAR, M N A, NEUBERGER, J, et al.NEUMANN, S. See ADEYEMI, E 0, NEUMANN, S, et al.NEWMAN, J. See DANESH, B J Z, BURKE, M, et al.News, 105, 216, 432, 540, 647, 760, 868, 984, 1098, 1274NG, M. See KUMANA, C R, NG, M, et al.

See LAM, S-K, LAI, C-L, et al.NIGAM, P, GUPTA, A K, KAPOOR, K K, SHARAN, G R, GOYAL, B M, and

JOSHI, L D: Cholestasis in amoebic liver abscess, 140NILAS, L, CHRISTIANSEN, C, and CHRISTIANSEN, J: Regulation of

vitamin D and calcium metabolism after gastrectomy, 252NISHIDA, K, SUGIURA, M, YOSHIKAWA, T, and KONDO, M: Enzymeimmunoassay of pancreatic oncofetal antigen as a marker ofpancreatic cancer, 450

NOLAN, D J. See JEFFREE M A, BARTER, S J, et al.NORRIS, T L. See JENKINSON, L R. NORRIS, T L, et al.NORTHFIELD, T C. See ZENTLER-MUNRO, P L, FINE, D R, et al.NORVAL, M. See GRAIL, A, and NORVAL, M

NOURI ARIA, K. See NEUBERGER, J, KENNA, G, et al.NOVICK, D M, ENLOW, R W, GELB, A M, STENGER, R J, FOTINO, M,WINTER, J W, YANCOVITZ, S R, SCHOENBERG, M D, and KREEK, M J:

Hepatic cirrhosis in young adults: association with adolescentonset of alcohol and parenteral heroin abuse, 8

NOVIS, B H. See GILINSKY, N H, MEE, A S, et al.Nufenoxole inhibiton of fluid secretion in human jejunum, 75Nutrition and disease activity in Crohn's disease, association with

vitamin D status, 1197, parenteral. See Parenteral nutrition

Nutritional value, relative, of whole protein, hydrolysed proteinand free amino acids, 694

NWABUNIKE, T O. See MELVILLE, R J, SULEIMAN, S I, et al.

Obesity, liver in, 133; (Letter), 1096O'BRIEN, J. See THOMPSON, D G, BINFIELD, P, et al.O'CONNOR, H J. See DICKINSON, R J, O'CONNOR, H J, et al.Oddi, sphincter of. See Sphincter of OddiOesophageal sphincter, lower, and distal oesophagus, influence ofmorphine on, manometric study, 802

-varices. See Varices, oesophagealOesophagitis, erosive, gastric juice bile acid concentrations in, 495

, oesophageal motor events at acid reflux and during endoge-nous acid exposure in, 336

Oesophagus, antrum and duodenum, histological appearances andcorrelation with symptoms in duodenal ulcer, 95

7 distal, and lower oesophageal sphincter, influence of mor-

phine on, manometric study, 802, motor activity, interdigestive and postprandial, effect

of cisapride, 246O'GRADY, J G, STEVENS, F M, and MCCARTHY, C F: Genetic influenceson splenic function in coeliac disease, 1004

OHMANN, C. See THON, K P, LORENZ, W, et al.(2'-5') Oligo adenylate synthetase activity in leucocytes in inflam-matory bowel disease, 556

Omeprazole and cimetidine, effect on aspirin- and taurocholate-induced gastric mucosal damage in rat, 770

effect on secretion of intrinsic factor, gastric acid and pepsin,594

intravenous, rapid rise in intragastric pH produced by, 90220 mg and 40 mg daily, basal, sham feed- and pentagastrin-

stimulated gastric acid, pepsin and electrolytes after, 1018Oncofetal antigen, pancreatic, enzyme immunoassay of, as marker

of pancreatic cancer, 450ORENSTEIN, M S, TAVITIAN, A, YONK, B, DINCSOY, H P, ZEREGA, J, IYER,

S K, and STRAUS, E w: Granulomatous involvement of the liver inpatients with AIDS, 1220

Onripressin enhancement of renal function in decompensatedalcoholic cirrhosis (Case report), 1385

ORTONA, L. See BARNABA, V, TAMBURRINI, E, et al.O'SHAUGHNESSY, D J. See SAGOR, G R, GHATEI, M A, et al.

PABA in serum as test for chronic pancreatitis (Letter), 537pancreatic function test in chronic alcohol induced pancreati-

tis, comparison with secretin-pancreozymin test and ERCP, 1257PACSOO, C. See MORGAN, A G, PACSOO, C, et al.PAIMELA, H, HARKONEN, M, KARONEN, S-L, TALLGREN, L G, STENMAN,

s, and AHONEN, J: Relation between serum group II pepsinogenconcentration and the degree of Brunner's gland hyperplasia inpatients with chronic renal failure, 198

PAIN, J A. See COLLIER, D ST J, and PAIN, J A

Pain, biliary-type, undefined, abnormal responses to morphine-neostigmine in patients with, 1367

, right upper quadrant, chronic, origin of, 783PALMER, K R, PATIL, D H, BASRAN, G S, RIORDAN, J F, and SILK, D B A:

Abdominal tuberculosis in urban Britain-a common disease,12%

Pancreas, carcinoma of, enzyme immunoassay of pancreaticoncofetal antigen as marker of, 450

, comparative radiological and morphological study withpattern and implication for ERCP of pancreatitis-like changes inpostmortem ductograms, 406; (Letter), 1095

, effect of injection pressure and volume, and pathogenesis ofacute gall stone pancreatitis, 615

, endocrine secretion, and gastric acid secretion in man,somatostatin as humoral regulator of, 445

, enzyme transfer to plasma during acute pancreatitis, contri-bution of ascitic fluid and lymphatic drainage to, 876

, short, congenital, 2 patients with (Case reports), 304Pancreatic duct, mucinous hyperplasia of, significance of, 825

endocrine tumours, somatostatin (SMS 201-995) treatment of,

1405

General index

symptomatic and peptide responses, 438enzyme secretion and secretin (Letters), 320juices and sera, monoclonal antibody defining CA 19-9 in, 456polypeptide and gastric acid responses to modified sham

feeding in duodenal ulcer and increased basal vagal tone in somepatients, 776

, motilin and gastrin concentrations, circulating, correla-tion with symptoms in functional bowel disorders, 1059

steatorrhoea due to cystic fibrosis, effect of cimetidine on

enzyme inactivation, bile acid precipitation. and lipid solubilisa-tion in, 892

Pancreatitis, acute, enzyme transfer from pancreas to plasmaduring, contribution of ascitic fluid and lymphatic drainage to,876

gall stone detection after, 125lethal character and increasing incidence, 724previous, impaired lipid clearance in patients with, 888

alcoholic, chronic, comparison of oral (PABA) pancreaticfunction test, secretin-pancreozymin test and ERCP in, 1257

, development of, diet and drinking habits in relation to,882

, chronic, calcifying, neuroendocrine islet cell tumour produc-ing gastrin and ACTH in (Case report), 426

, serum PABA test in (Letter), 537types of (Letter), 430

PAOLUZI, P, RICOTTA, G, RIPOLI, F, PROIETII, F, ZACCARDELLI, E,CARRATU, R, and TORSOLI, A: Incompletely and completely healedduodenal ulcers' outcome in maintenance treatment: a doubleblind controlled study (Clinical trial), 1080

PAPADIMITRIOU, C. See MANOUSOS, 0, DAY, N E, et al.

Para-aminobenzoic acid. See PABAParacetamol overdose, plasma glutathione S-transferase measure-

ments after, as evidence for early hepatocellular damage, 26PARENTE, F, LAZZARONI, M, SANGALETTI, 0, BARONI, s, and BIANCHI

PORRO, G: Cigarette smoking, gastric acid secretion and serumpepsinogen I concentrations in duodenal ulcer patients, 1327

Parenteral nutrition, total, in Crohn's disease, plasma and erythro-cyte selenium concentrations during, 50

PARKIN, J V. See MELVILLE, R J, SULEIMAN, s i, et al.

PARKS, T G. See SPENCE, R A J, COLLINS, B J, et al.PARSONS, M E: Histamine and the pathogenesis of duodenal ulcer

disease (Leading article), 1159PATEL, C. See ARTHUR, M J P, TANNER, A R, et al.PATIL, D H. See PALMER, K R. PATIL, D H, et al.PELED, Y: Methane excretion in man (Letter), 1270PENAGINI, R. See BASILISCO, G, BOZZANI, A, et al.

D-Penicillamine for pimary biliary cirrhosis (Leading article), 109trial of, 114

PEPPARD, J. See MULLOCK, B M, SHAW, L J, et al.Pepsin, gastric acid and electrolytes, basal, sham feed- and

pentagastrin-stimulated, after omeprazole 20 mg and 40 mgdaily, 1018

and intrinsic factor, secretion of, effect ofomeprazole, 594

Pepsinogen I, serum concentrations, gastric acid secretion andcigarette smoking in duodenal ulcer, 1327

group II, serum concentration in chronic renal failure,relation to degree of Brunner's gland hyperplasia, 198

Pepsinogens I and II, serum levels, and gastric mucosal histologyafter partial gastrectomy, 1179

Peptic ulcer, Campylobacter pyloridis in, microbiology, pathology,and scanning electron microscopy, 1183

pathogenesis and vagotomy, clinical trials on, sampletaking problems in measuring actual histamine levels of humangastroduodenal mucosa for, 1165

, perforated, and non-steroidal anti-inflammatory drugs,359; (Letters), 981

Peptide YY, plasma concentrations, raised, after intestinal resec-tion in rat, responsible for trophic response?, 1353

PEPYS, M B. See ADEYEMI, E 0, NEUMANN, s, et al.

Peritoneovenous shunt surgery for refractory ascites, morbidityand mortality after, 1070

Peritonitis, bacterial, spontaneous (Leading article), 325diagnosis from ascitic fluid pH in alcoholic

cirrhosis, reevaluation of, 332PETERS, A M. See SAVERYMUTrU, S H, PETERS, A M, et al.

PETERS, T J. See BJARNASON, 1, MARSH, M N, et al.- See BJARNASON, I, and PETERS, T J

See BJARNASON, 1, SMETHURST, P, et al.See STIEL, D, MURRAY, D J, et al.

PETERSEN, B. See LOUD, F B, HOLST, iJ, et al.pH catheter, combined manometry and antimony (MonocrystantMod 1010), problem with (Letter), 1271

-electrodes, plastic, for measurement of gastrointestinal pH,203

PHILLIPS, A D. See BURMAN, J F, JENKINS, w j, et al.PHILLIPS, E M. See WILSON, J A, and PHILLIPS, E M

Photocoagulation with Neodymium Yag laser, in treatment ofvascular malformations of gastrointestinal tract, long term resultsof, 586

PICK, C R. See POYNTER, D, PICK, C R, et al.PIEDELOUP, C. See JIAN, R, DUCROT, F, et al.PIEPOLI, V. See CALDARA, R, BARBIERI, c, et al.PIGNATA, C, TRONCONE, R, MONACO, G, CIRIACO, M, FARRIS, E,

CARMINATI, G, and AURICCHIO, S: Impaired supprcssor activity inchildren affected by coeliac disease, 285

PINCHING, A J. See WEBER, J N, CARMICHAEL, D J, et al.PINDER, I. See DICKINSON, R J, O'CONNOR, H J, et al.PINKERTON, C R, BOOTH, I W, and MILLA, P J: Topical methotrexate

alters solute and water transport in the rat jejunum in vivo andrabbit ileum in vitro, 704

PIPER, D W. See MCINTOSH, J H, BYTH, K, et al.Pirenzepine, effect on gastric acidity in healthy volunteers,

evaluation with 24-hour intragastric pH-monitoring, 241PIROLA, R C. See WILSON, J S, BERNSTEIN, L, et al.PISI, E. See VOLTA, U, LENZI, M, et al.PLANTIN, L-O. See JACOBSON, S, and PLANTIN, L-O

Plasma and erythrocyte selenium concentrations during totalparenteral nutrition in Crohn's disease, 50

cell infiltration of small bowel, no evidence for non-secretoryalpha-heavy chain disease in, 928

cells in duodenal bulb in duodenitis and duodenal ulceration,1032

-enteroglucagon and cell proliferation after intestinal resectionin rat, influence of somatostatin and bombesin, 89

, enzyme transfer from pancreas to, during acute pancreatitis,contribution of ascitic fluid and lymphatic drainage to, 876

glutathione S-transferase measurements after paracetamoloverdose as evidence for early hepatocellular damage, 26

peptide YY, raised, after intestinal resection in rat, responsi-ble for trophic response?, 1353

somatostatin, gastrin, and insulin, postprandial, autonomicregulation of, 683

Plasmapheresis, role in primary biliary cirrhosis. 291Platelet-associated immunoglobulins as cause of thrombocytopenia

in primary biliary cirrhosis, 1074POLLOCK, D J. See EARLAM, R J, AMERIGO, j, et al.POLYCHRONOPOULOU-TRICHOPOULOU, A. See MANOUSOS, 0, DAY, N E,

et al.Polyps and diverticula of large intestine, necropsy survey in HongKong, 1045

POMMER, W. See KELLER, F, WAGNER, K, et al.PORALLA, T. See STARITZ, M, PORALLA, T, et al.Portal hypertension and cirrhosis, propranolol pharmacology in, 14

, inflammatory gastritis or congestive gastropathy in,1226

PORTMANN, B. See NEUBERGER, J, CHRISTENSEN, E, et al.Posture change in cirrhosis and ascites, renal function impairmentinduced by, 629

POTET, F. See FILIPE, M I, POTET, F, et al.

1406

General index

POULSEN, S S. See SKOV OLSEN, P, POULSEN, S S, et al.POUNDER, R E. See ALLISON, M C, RENFREW, C C, et al.POYNTER, D, PICK, C R, HARCOURT, R A, SELWAY, S A M, AINGE, G,

HARMAN, I W, SPURLING, N W, FLUCK, P A, and COOK, J L:

Association of long lasting unsurmountable histamine H2 block-ade and gastric carcinoid tumours in the rat, 1284

PRANTERA, C. See LEVENSTEIN, S, PRANTERA, C, et al.Prednisolone enema, poorly absorbed, in distal colitis, therapeutic

benefits from, trial of, 822-in active Crohn's disease, comparative trial with elemental

diet plus non-absorbable antibiotics, 994PRESTON, D M, ADRIAN, T E, CHRISTOFIDES, N D, LENNARD-JONES, J E,

and BLOOM, S R: Positive correlation between symptoms andcirculating motilin, pancreatic polypeptide and gastrin concen-

trations in functional bowel disorders, 1059PRICE, A. See BJARNASON, 1, MARSH, M N, et al.PRICE, A B, LEVI, J, DOLBY, J M, DUNSCOMBE, P L, SMITH, A, CLARK, J,

and STEPHENSON, M L: Campylobacter pyloridis in peptic ulcerdisease: microbiology, pathology, and scanning electron micros-copy, 1183

PRICE, S. See GILINSKY, N H, MEE, A S, et al.Proctocolitis, incidence of colorectal cancer in, study of 959 cases

over 40 years, 43, ulcerative, crypt cell production rate in, differential incre-

ments in remission and relapse, 999PROIETTI, F. See PAOLUZI, P, RICOTTA, G, et al.Propranolol disposition in cirrhosis (Letter), 865

, pharmacology in cirrhosis and portal hypertension, 14Prostaglandin El analogues. See Misoprostol

E2, jejunal concentrations, increase in acute cholera, 188level in gastric lumen, reduction by cigarette smoking,

1192synthesis in gastric mucosa, inhibition by indomethacin,

somatostatin inhibition of gastric acid secretion after, 1189Prostaglandins not mediators of intestinal response to cholera

toxin, 680, synthesis in duodenal mucosa in duodenal ulcer disease, 237

Protein absorption, intestinal, in normal man, influence of proteincomposition and hydrolysis method, 907

deficiency and rehabilitation, small intestinal mucosa inyoung, adult, and old rats submitted to, morphometric study of,816

, whole, hydrolysed protein and free amino acids, relativenutritional value of, 694

Protein-losing enteropathy due to systemic lupus erythematosus(Letters), 757

Proteins in human bile, sources of, 500Protozoan infestations, unusual, frequency in AIDS shown by 4

cases with diarrhoea and malabsorption, 179Puborectalis and external anal sphincter muscles, innervation to, in

anorectal incontinence and rectal prolapse, 470PURVES, L R. See GILINSKY, N H, MEE, A S, et al.

QUATRINI, M, BASILISCO, G, and BIANCHI, P A: Cimetidine versus

ranitidine in short term healing of duodenal ulcers (Letter), 642See also BASILISCO, G, BOZZANI, A, et al.

QUENUM, C. See BRAILLON, A, CAPRON, J P, et al.QUIGLEY, E M M. See DUHRA, P M, QUIGLEY, E M M, et al.

RABBANI, G H. See SPEELMAN, P, RABBANI, G H, et al.RACHMILEWITZ, D. See STALNIKOWICZ, R, GODER, K, et al.RAINEY, J B, MAEDA, M, and WILLIAMSON, R C N: Distal transposition

of rat caecum does not render it susceptible to carcinogenesis,718

RAMBAUD, J-C. See MIAZZA, B M, AL-MUKHTAR, M Y T, et al.See MODIGLIANI, R, BORIES, C, et al.

RANEK, L. See NEUBERGER, J, CHRISTENSEN, E, et al.Ranitidine alone and ranitidine plus Caved-S in treatment of gastric

ulceration, comparative study (Clinical trial), 1377and sucralfate combined in subtherapeutic doses for preven-

tion of duodenal ulcers in rat, 603versus cimetidine in short term healing of duodenal ulcers

(Letters), 642RASK-MADSEN, J. See SPEELMAN, P, RABBANI, G H, et al.RAWLINGS, J M, and LUCAS, M L: Plastic pH electrodes for themeasurement of gastrointestinal pH, 203

READ, N W, AL-JANABI, M N, BATES, T E, HOLGATE, A M, CANN, P A,

KINSMAN, R 1, MCFARLANE, A, and BROWN, C: Interpretation of thebreath hydrogen profile obtained after ingesting a solid mealcontaining unabsorbable carbohydrate, 834

RECCHIA, M. See BASILISCO. G, BOZZANI, A, et al.RECORD, C 0. See BRAMBLE, M G, ZUCOLOTO, S, et al.Rectal absorption and excretion of topical 5-aminosalicylic acidenemas in ulcerative colitis, 400

mucosal morphologic abnormalities in normal subjects insouthern India designated as 'tropical colonopathy', 710

mucus, normal and in inflammatory bowel disease, desialationand desulphation by faecal extracts, histochemical demonstra-tion of, 1312

prolapse and anorectal incontinence, innervation to puborec-talis and external anal sphincter muscles in, 470

Rectum, balloon explusion from, in constipation of different types,1049

REDEKER, A G. See DE COCK, K M, GOVINDARAJAN, S, et al.REED, L A. See CONTALDO, F, MANCINI, M, et al.REES, H. See SAVERYMUTTU, S H, PETERS, A M, et al.REES, L H. See LUCEY, M R, WASS, J A H, et al.Reflux, duodenogastric, and gastric secretion, effect of cimetidine,766

gastro-oesophageal, normal, influenced by age?, 799, oesophageal motor events at, in healthy subjects and in

oesophagitis, 336Rehydration therapy, oral, citrate in (Letters), 429Renal failure, chronic, relation between serum pepsinogen group II

concentration and degree of Brunner's gland hyperplasia in, 198function enhancement with ornipressin in decompensated

alcoholic cirrhosis (Case report), 1385impairment induced by posture change in cirrhosis and

ascites, 629RENFREW, C C. See ALLISON, M C, RENFREW, C C, et al.RENWICK, A G. See ARTHUR, M J P, TANNER, A R, et al.Reticulin binding property of cereal proteins in vitro, role in

pathogenesis of coeliac disease?, 1204REYNOLDS, J R. See WALT, R P, REYNOLDS, J R, et al.RHODES, J. See HARRIES, A D, BROWN, R, et al.RHODES, J M, BLACK, R R, GALLIMORE, R, and SAVAGE, A: Histo-

chemical demonstration of desialation and desulphation ofnormal and inflammatory bowel disease rectal mucus by faecalextracts, 1312

, GALLIMORE, R, ELIAS, E, and KENNEDY, J F: Faecal sulphatasein health and in inflammatory bowel disease, 466

ALLAN, R N, and KENNEDY, J F: Faecal mucus

degrading glycosidases in ulcerative colitis and Crohn's disease,761

, MARSHALL, T, HAMER, J D, and ALLAN, R N: Crohn's disease intwo married couples (Case reports), 1086

RICOTTA, G. See PAOLUZI, P, RICOTTA, G, et al.RIORDAN, J F. See PALMER, K R, PATIL, D H, et al.RIPOLI, F. See PAOLUZI, P, RICOTTA, G, et al.RIVIER, J E. See LENZ, H J, MORTRUD, M T, et al.RIZZETTO, M. See FARCI, P, BARBERA, C, et al.ROBB, T A, DAVIDSON, G P, and KIRUBAKARAN, C: Conjugated bile

acids in serum and secretions in response to cholecystokinin/secretin stimulation in children with cystic fibrosis, 1246

ROBERTS-THOMSON, I C, and TOOULI, J: Abnormal responses tomorphine-neostigmine in patients with undefined biliary typepain, 1367

ROBERTSON, D A F. See FOSTER, P N, BULLEN, A W, et al.

1407

General index

ROBINS-BROWNE, R M. See TZIPORI, S, ROBINS-BROWNE, R M, et al.RODES, J. See NEUBERGER, J, CHRISTENSEN, E, et al.RODRIGUES, M A M, DE CAMARGO, J L V, COELHO, K I R, MONTENEGRO,

M R G, ANGELELI, A Y o, and BURINI, R C: Morphometric study ofthe small intestinal mucosa in young, adult, and old ratssubmitted to protein deficiency and rehabilitation, 816

ROFE, S B, DUGGAN, J M, SMITH, E R, and THURSBY, C J: Conservativetreatment of gastrointestinal haemorrhage, 481; (See also Letterby Duggan, 1272)

ROHDE, H. See THON, K P, LORENZ, w, et al.ROHER, H D. See THON, K P, LORENZ, W, et al.ROLSTON, D D K, FARTHING, M J G, CLARK, M L, and DAWSON, A M:

Citrate in oral rehydration therapy (Letter). 429See also MORIARTY, K J, ROLSTON, D D K, et al.

ROSEKRANS, P C M. See VAN SPREEUWEL, J P, DUURSMA, G C, et al.ROSS, G. See HILLIER, K, SMITH, C L, et al.ROUDOT-THORAVAL, F. See SAINT-MARC GIRARDIN, M-F, LE MINOR, M,

et al.Rowachol, etfect on biliary lipid secretion and serum lipids in

normal volunteers, 32RUBINSTEIN, D, MCINNES, I, and DUDLEY, F: Morbidity and mortality

after peritoneovenous shunt surgery for refractory ascites, 1070RUEFF, B. See BERCOFF, E, BERNUAU, J, et al.RUNE, S J. See ANDERSEN, B N, LARSEN, N-E, et al.RUOCCO, G. See BARNABA, V, TAMBURRINI, E, et al.RUTGEERTS, P, VAN GOMPEL, F, GEBOES, K, VANTRAPPEN, G, BROECK-

AERT, L, and COREMANS, G: Long term results of treatment ofvascular malformations of the gastrointestinal tract by Neody-mium Yag laser photocoagulation, 586

SACHDEVA, G K. See SARIN, S K, SACHDEVA, G K, et al.SAGOR, G R, GHATEI, M A, O'SHAUGHNESSY, D J, AL-MUKHTAR, M Y T,

WRIGHT, N A, and BLOOM, S R: Influence of somatostatin andbombesin on plasma enteroglucagon and cell proliferation afterintestinal resection in the rat, 89

SAINT-MARC GIRARDIN, M-F, LE MINOR, M, ALPEROVITCH, A, ROUDOT-

THORAVAL, F, METREAU, J-M, and DHUMEAUX, D: Computer-aidedselection of diagnostic tests in jaundiced patients, 961

SALIM, A S M. See UTLEY, R J, SALIM, A S M, et al.SALMERON, M. See MIAZZA, B M, AL-MUKHTAR, M Y T, et al.

See MODIGLIANI, R, BORIES, C, et al.SALMON, P R. See BOWN, S G, SWAIN, C P, et al.Salmonella typhimurium food poisoning, alimentary tract pathol-

ogy in, 935SAMLOFF, I M. See SIPPONEN, P, SAMLOFF, M, et al.SANGALETTI, o. See PARENTE, F, LAZZARONI, M, et al.SANTINI, C. See BERNARDI, M, SANTINI, C, et al.Sarcoma, Kaposi's, of bowel presenting as apparent ulcerative

colitis (Case report), 295SARIN, S K, SACHDEVA, G K, NANDA, R, VIJ, J C, and ANAND, B S:

Endoscopic sclerotherapy using absolute alcohol, 120SAUKKONEN, M. See SIPPONEN, P, SAMLOFF, M, et al.SAUNDERS, P. See BASSENDINE, M F, COLLINS, J D, et al.SAVAGE, A. See RHODES, J M, BLACK, R R, et al.SAVAGE, A P, GORNACZ, G E, ADRIAN, T E, GHATEI, M A, GOODLAD, R A,

WRIGHT, N A, and BLOOM, S R: Is raised plasma peptide YY afterintestinal resection in the rat responsible for the trophicresponse?, 1353

SAVERYMUTTU, S H, HODGSON, H J F, and CHADWICK, V S: Controlledtrial comparing prednisolone with an elemental diet plusnon-absorbable antibiotics in active Crohn's disease, 994

, PETERS, A M, CROFTON, M E, REES, H, LAVENDER, J P, HODGSON,

H J F, and CHADWICK, V S: "'Indium autologous granulocytesin the detection of inflammatory bowel disease, 955

, LAVENDER, J P, CHADWICK, V S, and HODGSON, H J F: Invivo assessment of granulocyte migration to diseased bowel inCrohn's disease, 378

SCEMAMA-CLERGUE,J, DOUTRELLOT-PHILIPPON, C, METREAU, J-M, TEIS-

SEIRE, B, CAPRON, D, and DHUMEAUX, D: Ascitic fluid pH in

alcoholic cirrhosis: a reevaluation of its use in the diagnosis ofspontaneous bacterial peritonitis, 332

SCHAFFNER F. See COHEN, L B, AMBINDER, E P, et al.SCHJ0NSBY, H. See KrITANG, E, AADLAND, E, et al.SCHMIEGEL, W H, KREIKER, C, EBERL, W, ARNDT, R, CLASSEN, M,

GRETEN, H, JESSEN, K, KALTHOFF, H, SOEHENDRA, N, and THIELE,H-G: Monoclonal antibody defines CA 19-9 in pancreatic juicesand sera, 456

SCHMITZ-MOORMANN, P, HIMMELMANN, G W, BRANDES, J-W, FOLSCH,U R, LORENZ-MEYER, H, MALCHOW, H, SOEHENDRA, L N, andWIENBECK, M: Comparative radiological and morphological studyof human pancreas: pancreatitis like changes in postmortemductograms and their morphological pattern: possible implica-tion for ERCP, 406

SCHNEEWEISS, B. See LENZ, K, DRUML, W, et al.SCHOENBERG, M D. See NOVICK, D M, ENLOW, R W, et al.SCHOFIELD, P F: Abdominal tuberculosis (Leading article), 1275Sclerotherapy, endoscopic, using absolute alcohol, 120

, injection, for long term management of variceal bleeding in

cirrhosis, comparison with oral metoprolol (Clinical trial), 421SCOTT, B B, GOODALL, A, STEPHENSON, P, and JENKINS, D: Duodenal

bulb plasma cells in duodenitis and duodenal ulceration, 1032Secretin and pancreatic enzyme secretion (Letters), 320Secretin-pancreozymin test in chronic alcohol induced pancreatitis,comparison with oral (PABA) pancreatic function test andERCP, 1257

Selenium, plasma and erythrocyte concentrations during totalparenteral nutrition in Crohn's disease, 50

SELIGSON, U. See MAGNUSSON, 1, IHRE, T, et al.SELWAY, S A M. See POYNTER, D, PICK, C R, et al.Sepsis, gastric mucosal damage in, effects of pretreatment with

misoprostol, 1025Serum and pancreatic juices, monoclonal antibody defining CA

19-9 in, 456and secretions, conjugated bile acid levels in response to

cholecystokinin/secretin stimulation in children with cystic fibro-sis, 1246

collagenolytic enzyme inhibitors in chronic liver disorders,1364

lipid concentrations and biliary lipid secretion, effect ofRowachol in normal volunteers, 32PABA test in chronic pancreatitis (Letter), 537pepsinogen I concentrations, gastric acid secretion and

cigarette smoking in duodenal ulcer, 1327group II concentration in chronic renal failure, relation

to degree of Brunner's gland hyperplasia, 198pepsinogens I and II and gastric mucosal histology after

partial gastrectomy, 1179-, urine and bile, profiles of bile acids and glucuronide and

sulphate conjugates during and after bile drainage in, 38SEVERI, C. See KOHN, A, ANNIBALE, B, et al.SEYAMA, Y. See TAKIKAWA, H, BEPPU, T, et al.Sham feeding, modified, gastric acid and pancreatic polypeptide

responses to, in duodenal ulcer, and increased basal vagal tone insome patients, 776

SHARAN, G R. See NIGAM, P, GUPTA, A K, et al.SHAW, L J. See MULLOCK, B M, SHAW, L J, et al.SHERLOCK, S. See WELLER, V D, LOK, A S F, et al.SHIELD, M. See MORIARTY, K J, ROLSTON, D D K, et al.SHIELDS, R. See BAXIER, J N, GRIME, J S, et al.SHORVON, PJ, COPI'ON, P B, MASON, R R, SIEGEL, J H, and HATFIELD,

A R W: Percutaneous transhepatic assistance for duodenoscopicsphincterotomy, 1373

SHOULER, P. See FABRICIUS, P J, GYDE, S N, et al.SHPIRER, Z. See BAR-MEIR, S, HALPERN, Z, et al.SIEGEL, J H. See SHORVON, PJ, COTTON, P B, et al.Sigmoid colon, diverticular disease of, elastosis in, 258SILK, D B A. See KEOHANE, P P, GRIMBLE, G K, et al.

See PALMER, K R, PATIL, D H, et al.SIMPSON, M T. See MULLOCK, B M, SHAW, LJ, et al.

1408

General index

SIMS, J. See MCCORMACK, T T, SIMS, 1, et al.SIPPONEN, P, SAMLOFF, I M, SAUKKONEN, M, and VARIS, K: Serum

pepsinogens I and 11 and gastric mucosal histology after partialgastrectomy, 1179

SKINNER, D B. See DOWLATSHAHI, K, EVANDER, A, et al.SKOV OLSEN, P, POULSEN, s s, and KIRKEGAARD, P: Adrenergic effectson secretion of epidermal growth factor from Brunner's glands,920

SMART, H L. See WALT, R P, REYNOLDS, J R, et al.SMETHURST, P. See BJARNASON, 1, SMETHURST, P, et al.SMITH, A. See PRICE, A B, LEVI, j, et al.SMITH, A N. See WAY[ERS, D A K, SMITH, A N. et al.SMITH, C L. See HILLIER, K, SMITH, C L, et al.SMITH, E R. See ROFE, S B, DUGGAN, J M, et al.SMITH, G S, WARHURST, G, TONGE, A, and TURNBERG, L A: Prostaglan-

dins are not mediators of the intestinal response to cholera toxin,680

Smoking, cigarette, gastric acid secretion and serum pepsinogen Iconcentrations in duodenal ulcer, 1327

, influence on duodenal ulcer healing by cimetidine andulcer persistence or relapse, 1333

, reduction of gastric luminal prostaglandin E2 by, 1192SMOLOW, C. See BANK, S, ZIMMERMAN, H, et al.SMOUT, A J P M, BOGAARD, J W, GRADE, A C, TEN THIJE, 0 J,AKKERMANS, L M A, and wiIrrEBOL, P: Effects of cisapride, a new

gastrointestinal prokinetic substance, on interdigestive andpostprandial motor activity of the distal oesophagus in man, 246

SMS 201-995 for management of endocrine tumours (Leadingarticle), 433

treatment of pancreatic endocrine tumours, symptomaticand peptide responses, 438

SNOOKS, S J, HENRY, M M, and SWASH, M: Anorectal incontinence andrectal prolapse: differential assessment of the innervation topuborectalis and external anal sphincter muscles, 470

SOEHENDRA, L N. See SCHMIrZ-MOORMANN, P, HIMMELMANN, G W,

et al.SOEHENDRA, N. See SCHMIEGEL, W H, KREIKER, C, et al.Solute and water transport in rat jejunum in vivo and rabbit ileum

in vitro, alteration by topical methotrexate, 704Somatostatin analogues, long-acting. See SMS 201-995

and bombesin, influence on plasma enteroglucagon and cellproliferation after intestinal resection in rat, 89

as humoral regulator of endocrine pancreas and gastric acidsecretion in man, 445

, gastrin, and insulin, postprandial plasma levels, autonomicregulation of, 683

in treatment of massive upper gastrointestinal haemorrhage,trial of, 221

inhibition of gastric acid secretion after gastric mucosalprostaglandin synthesis inhibition by indomethacin, 1189

SOMERVILLE, K W. See WALT, R P, REYNOLDS, J R, et al.SOURIAL, N A. See BURMAN, J F, JENKINS, W J, et al.SPEELMAN, P, RABBANI, G H, BUKHAVE, K, and RASK-MADSEN, J:

Increased jejunal prostaglandin E2 concentrations in patientswith acute cholera, 188

SPENCE, R A J, COLLINS, B J, PARKS, T G, and LOVE, A H G: Does ageinfluence normal gastro-oesophageal reflux?, 799

SPENCER, J. See THOMPSON, J N, BARR, J A, et al.SPENCER, J, FINN, T, and ISAACSON P G: Gut associated lymphoid

tissue: a morphological and immunocytochemical study of thehuman appendix, 672

Sphincter, anal, external, musculature, and puborectalis muscle,innervation to, in anorectal incontinence and rectal prolapse, 470

, oesophageal, lower, and distal oesophagus. influence ofmorphine on, manometric study, 802

of Oddi motility and baseline pressure, effect of glyceryltrinitrate, 194

Sphincterotomy, biliary, endoscopic, medium term complicationsof, 730-, duodenoscopic, percutaneous transhepatic assistance for,

1373SPIEGELHALTER, D J. See LANGMAN, M J S, MCCONNELL, T H, et al.SPILLER, R C. See KEOHANE, P P, GRIMBLE, G K, et al.SPINELLA, S. See KOHN, A, ANNIBALE, B, et al.Splenic function, impairment in intestinal lymphangiectasia,development of (Case report), 861- in coeliac disease, genetic influences on, 1004

SPURLING, N W. See POYNTER, D, PICK, C R, et al.STALNIKOWICZ, R, GODER, K, KARMELI, F, FIOCCHI, c, and RACHMILE-

WITZ, D: (2'-5') Oligo adenylate synthetase activity in leucocytesof patients with inflammatory bowel disease, 556

S1'ARITZ, M, PORALLA, T, EWE, K, and MEYER ZUM BUSCHENFELDE, K-H:Effect of glyceryl trinitrate on the sphincter of Oddi motility andbaseline pressure, 194

and MEYER ZUM BUSCHENFELDE, K-H: Intravascularoesophageal variceal pressure assessed by endoscopic fine needlepuncture under basal conditions, Valsalva's manoeuvre and afterglyceryltrinitrate application, 525

Steatorrhoea, pancreatic, due to cystic fibrosis, effect of cimetidineon enzyme inactivation, bile acid precipitation, and lipidsolubilisation in, 892

STENGER, R J. See NOVICK, D M, ENLOW, R W, et al.STENMAN, S. See PAIMELA, H, HARKONEN, M, et al.STEPHENSON, J. See BASSENDINE, M F, COLLINS, J D, et al.STEPHENSON, M L. See PRICE, A B, LEVI, J, et al.STEPHENSON, P. See SCOTT, B B, GOODALL, A, et al.STEVENS, F M. See O'GRADY, J G, STEVENS, F M, et al.STIEL, D, MURRAY, D J, and PETERS, T J: Uptake and subcellular

localisation of bismuth in the gastrointestinal mucosa of rats aftershort term administration of colloidal bismuth subcitrate, 364

STOREY, D W. See BOWN, S G, SWAIN, C P, et al.STRAUS, E W. See ORENSTEIN, M S, TAVITIAN, A, et al.Sucralfate and ranitidine combined in subtherapeutic doses for

prevention of duodenal ulcers in rat, 603SUGIURA, M. See NISHIDA, K, SUGIURA, M, et al.SULEIMAN, S 1. See MELVILLE, R J, SULEIMAN, S I, et al.Sulphatase, faecal, in health and in inflammatory bowel disease,466

Suppressor activity, impairment in children affected by coeliacdisease, 285

SURIANO, G. See KOHN, A, ANNIBALE, B, et al.SUTTON, J A. See MCCLELLAND, G R, and SUTrON, J ASWAIN, C P. See BOWN, S G, SWAIN, C P, et al.SWASH, M. See SNOOKS, S J, HENRY, M M, et al.

T cells, regulatory, and mononuclear cells in peripheral blood inacute viral hepatitis, 739

TABACCHI, P. See CORAZZA, G R, TABACCHI, P, et al.TAGESSON, C, FRANZEN, L, DAHL, G, and WESTROM, B: Lysophospha-

tidylcholine increases in rat ileal permeability to macro-

molecules, 369TAIT, A. See WILSON, J S, BERNSTEIN, L, et al.TAKIKAWA, H, BEPPU, T, and SEYAMA, Y: Profiles of bile acids and

their glucoronide and sulphate conjugates in the serum, urineand bile from patients undergoing bile drainage, 38

TALLGREN, L G. See PAIMELA, H, HARKONEN, M, et al.TAMBURRINI, E. See BARNABA, V, TAMBURRINI, E, et al.I'ANNER, A R. See ARTHUR, M J P, TANNER, A R, et al.Taurocholate and aspirin, gastric mucosal damage in rat induced

by, effect of cimetidine and omeprazole, 770TAVITIAN, A. See ORENSTEIN, M S, TAVITIAN, A, et al.TAYLOR, C J. See COTTONE, M, BUNCE, M, et al.1'AYLOR, 1. See GOEI'ING, N, TROTTER, G A, et al.

See TROTrER, G A, MORGAN, G R, et al.TAYLOR, T V. See ARMSTRONG, C P, TAYLOR, T V, et al.Tea, herbal, hepatic veno-occlusive disease induced by, quantifica-

tion of toxic alkaloid exposure in adults with (Case reports), 101TEISSEIRE, B. See SCEMAMA-CLERGUE, J, DOUTRELLOT-PHILIPPON, C,

et al.

1409

General index

TEN THIJE, O J. See SMOUT, A J P M, BOGAARD, J W, et al.

TESTA, S. See BOLONDI, L, GAIANI, S, et al.THIELE, H-G. See SCHMIEGEL, W H, KREIKER, C, et al.THOMAS, H C: The delta agent comes of age (Leading article), 1

See also LEE, C A, KERNOFF, P B A, et al.See also WELLER, I V D, LOK, A S F, et al.See also WIEDMANN, K H, TREJDOSIEWICZ, L K, et al.

THOMPSON, D G, BINFIELD, P, DE BELDER, A, O'BRIEN, J, WARREN, S,

and WILSON, M: Extra intestinal influences on exhaled breathhydrogen measurements during the investigation of gastrointes-tinal disease, 1349

THOMPSON, J N, BARR, J A, COLLIER, N, SPENCER, J, BUSH, A, COPE, L

GRIBBLE, R J N and BARON, J H: Basal, sham feed and pentagastrinstimulated gastric acid, pepsin and electrolytes after omeprazole20 mg and 40 mg daily, 1018

THON, K P, LORENZ, W, OHMANN, C, WEBER, D, ROHDE, H, andROHER, H D: Sample taking problems in measuring actualhistamine levels of human gastroduodenal mucosa: specific andgeneral relevance in clinical trials on peptic ulcer pathogenesisand selective proximal vagotomy, 1165

Thrombocytopenia in primary biliary cirrhosis, platelet-associatedimmunoglobulins as cause of, 1074

THURSBY, C J. See ROFE, S B, DUGGAN, J M, et al.TILLY, H. See BERCOFF, E, BERNUAU, J, et al.TING, A. See COTITONE, M, BUNCE, M, et al.TODD, D. See KUMANA, C R, NG, M, et al.TOLENTINO, P. See FARCI, P, BARBERA, c, et al.Tomography. See Computer-assisted tomographyTONGE, A. See SMITH, G S, WARHURST, G, et al.TOOULI, J. See ROBERTS-THOMSON, I C, and TOOULI, J

TORNERO MOLINO, J. See CASTANEDA SANZ, S, HERRERO-BEAUMONT, G,

et al.TORNGREN, S. See MAGNUSSON, I, IHRE, T, et al.TORRANCE, H B. See ARMSTRONG, C P, TAYLOR, T v, et al.

TORSOLI, A. See PAOLUZI, P, RICOTTA, G, et al.Transplantation of liver, therapeutic potential of, and clinical

course of disease, in cirrhosis in young adults, 1359TREJDOSIEWICZ, L K. See WIEDMANN K H, TREJDOSIEWICZ, L K, et al.

TREVISANI, F. See BERNARDI, M, SANTINI, C, et al.

TRICHOPOULOS, D. See MANOUSOS, 0, DAY, N E, et al.

TRIGER, D R. See MCCORMACK, T T, SIMS, j, et al.TROLLOPE, M L. See BABB, R R, and TROLLOPE, M L

TRONCONE, R. See PIGNATA, C, TRONCONE, R, et al.

TROYIER, G A, MORGAN, G R, COOPER, A J, KIRKHAM, N, WHITEHOUSE,J M A, and TAYLOR, 1: Cell kinetics and in vitro clonogenicity ofprimary colorectal cancer: clinicopathological relationships andthe implications for chemotherapy, 267-. See also GOETING, N, TROTT7ER, G A, et al.Tuberculosis, abdominal (Leading article), 1275

-, -, in urban Britain (experience of W. London districtgeneral hospital, 1973-83), 1296

Tumour, carcinoid, of ileum, bleeding, endoscopic diagnosis of(Letter), 431

, islet cell, neuroendocrine, producing gastrin and ACTH incalcifying chronic pancreatitis (Case report), 426

Tumours, carcinoid, gastric, and inhibition of gastric acid secretion(Leading article), 1279,-,1 , association with long lasting unsurmountable

histamine H2 blockade with loxtidine in rat, 1284-, endocrine, pancreatic, somatostatin (SMS 201-995) treat-ment of, symptomatic and peptide responses, 438

, -1,somatostatin (SMS 201-995) for management of(Leading article), 433

TURNBERG, L A. See SMITH, G S, WARHURST, G, et al.

TYGSTRUP, N. See NEUBERGER, J, CHRISTENSEN, E, et al.

Typhoid fever, gastric acid secretion in, 491; (Letters), 1387TZIPORI, S, ROBINS-BROWNE, R M, GONIS, G, HAYES, J, WITHERS, M, and

MCCARTNEY, E: Enteropathogenic Escherichia coli enteritis: eva-

luation of the gnotobiotic piglet as a model of human infection,570

TZONOU, A. See MANOUSOS, 0, DAY, N E, et al.

Ulcer healing studies, choice of appropriate statistical test in(Letter), 643; (Letter), 1096

See also under Duodenum; Gastric; PepticUNSWORTH, D 1, and HOLBOROW, E i: Does the reticulin binding

property of cereal proteins demonstrable in vitro have patho-genetic significance for coeliac disease?, 1204

Urine, serum and bile, profiles of bile acids and glucuronide andsulphate conjugates during and after bile drainage in, 38

UTLEY, R I, SALIM, A S M, and CARTER, D C: Effect of cimetidine andomeprazole on aspirin- and taurocholate-induced gastric mucosaldamage in the rat, 770

UVNAS-MOBERG, K. See MAGNUSSON, 1, IHRE, T, et al.

Vagal tone, basal, increase in some duodenal ulcer patients andgastric acid and pancreatic polypeptide responses after modifiedsham feeding, 776

Vagotomy and peptic ulcer pathogenesis, clinical trials on, sampletaking problems in measuring actual histamine levels of humangastroduodenal mucosa for, 1165

VAIRO, P. See FARCI, P, BARBERA, c, et al.VALDIVIESO, V. See GUZMAN, S, NERVI, F, et al.Valsalva's manoeuvre, intravascular oesophageal variceal pressure

assessed by endoscopic fine needle puncture after, 525Vancomycin, oral, as adjunctive treatment in acute exacerbations

of idiopathic colitis (Clinical trial), 1380VAN DEVENTER, G. See MOGARD, M H, MAXWELL, V, et al.

VAN GOMPEL, F. See RUTGEERTS, P, VAN GOMPEL, F, et al.

VAN SPREEUWEL, J P, DUURSMA, G C, MEIJER, C J L M, BAX, R,

ROSEKRANS, P C M, and LINDEMAN, J: Campylobacter colitis:histological, immunohistochemical and ultrastructural findings,945

VAN TONGEREN, J H M. See CLUYSENAER, o i J, and VAN TONGEREN,

J H M

VANTRAPPEN, G. See RUTGEERTS, P, VAN GOMPEL, F, et al.VARGHESE, A. See BHALLA, s, vIJ, i c, et al.

Varices, bleeding, in cirrhosis, long term management of, oralmetoprolol compared with injection sclerotherapy for (Clinicaltrial), 421-, oesophageal, endoscopic pressure measurements, response

to isosorbide dinitrate, 843-,-, intravascular pressure in, assessment by endoscopic

fine needle puncture under basal conditions, after Valsalva'smanoeuvre and after glyceryltrinitrate application, 525

VARIS, K. See SIPPONEN, P, SAMLOFF, I M, et al.Vascular anomalies of upper gastrointestinal tract, endoscopic laser

treatment of, 1338malformations of gastrointestinal tract, treatment by Neody-

mium Yag laser photocoagulation, long term results of, 586VEGNENTE, A. See FARCI, P, BARBERA, c, et al.VERHAAR, H J J. See GIBSON, P R, HERMANOWICZ, A, et al.VERNAY, M Y. See MARTY, J F, VERNAY, M Y, et al.VIJ, J C, ANAND, B s, and CHUTTANI, H K: Gastric secretion in patients

with typhoid (Letter), 1387See also BHALLA, S, VII, J C, et al.See also SARIN, S K, SACHDEVA, G K, et al.

VILLET, R. See MIAZZA, B M, AL-MUKHTAR, M Y I, et al.Viral hepatitis, acute, peripheral blood mononuclear cells and

regulatory T cells in,, 739Vitamin B12 malabsorption, familial, with proteinuria. See Im-

erslund-Grasbeck syndromeD and calcium metabolism, regulation after gastrectomy, 252

status in Crohn's disease, association with nutrition anddisease activity, 1197

VOLTA, U, LENZI, M, LAZZARI, R, CASSANI, F, COLLINA, A, BIANCHI,F B, and PISI, E: Antibodies to gliadin detected by immuno-fluorescence and a micro-ELISA method: markers of active

1410

General index

childhood and adult coeliac disease, 667VON BERGMANN, K. See LEISS, o, and VON BERGMANN, K

WAGNER, K. See KELLER, F, WAGNER, K, et al.WALKER, E. See MEE, A S, GIRDWOOD, A H, et al.WALKER, R. See COOPER, R G, DOCKRAY, G J, et al.WALKER-SMITH, J A. See BURMAN, J F, JENKINS, W J, et al.

See CHONG, S K F, BLACKSHAW, A J, et al.WALSH, J H. See MOGARD, M H, MAXWELL, V, et al.WALT, R P, REYNOLDS, J R, LANGMAN, M J S, SMART, H L,

KITCHINGMAN, G, SOMERVILLE, K W, and HAWKEY, C J: Intravenousomeprazole rapidly raises intragastric pH, 902

WALTHER, B. See DOWLATSHAHI, K, EVANDER, A, et al.Warfarin, effect on cell kinetics, epithelial morphology and tumour

incidence in induced colorectal cancer in rat, 807WARHURST, G. See SMITH, G S, WARHURST, G, et al.WARIN, A P. See FREEMAN, K, ANTHONY, P P, et al.WARREN, S. See THOMPSON, D G, BINFIELD, P, et al.WASS, J A H. See LUCEY, M R, WASS, J A H, et al.Water and solute transport in rat jejunum in vivo and rabbit ileum

in vitro, alteration by topical methotrexate, 704WATKINS, R M, DENNISON, A R, and COLLIN, J: Drug therapy and

perforated peptic ulcer (Letter), 981WATSON, A. See JENKINSON, L R, NORRIS, T L, et al.WATSON, G J. See LEDGER, J E, WATSON, G J, et al.WATTERS, D A K, SMITH, A N, EASTWOOD, M A, ANDERSON, K C, ELTON,

R A, and MUGERWA, J W: Mechanical properties of the colon:comparison of the features of the African and European colon invitro, 384

WEBB, J. See LUCEY, M R, WASS, J A H, et al.WEBB, S. See LUCEY, M R, WASS, J A H, et al.WEBB, W J S. See ALLISON, M C, RENFREW, C C, et al.WEBER, D. See THON, K P, LORENZ, W, et al.WEBER, J N, CARMICHAEL, D J, BOYLSTON, A, MUNRO, A, WHITEAR, W P,and PINCHING, A J: Kaposi's sarcoma of the bowel-presentingas apparent ulcerative colitis (Case report), 295

WELLER, I V D: The gay bowel (Leading article), 869, LOK, A S F, MINDEL, A, KARAYIANNIS, P, GALPIN, S,

MONJARDINO, J, SHERLOCK, S, and THOMAS, H C: Randomisedcontrolled trial of adenine arabinoside 5'-monophosphate(ARA-AMP) in chronic hepatitis B virus infection (Clinicaltrial), 745

WEST, R. See DAWSON, J, GERTSCH, P, et al.WESTABY, D, MELIA, W M, MACDOUGALL, B R D, HEGARTY, J E, GIMSON,A E, and WILLIAMS, R: B, selective adrenoreceptor blockade forthe long term management of variceal bleeding: a prospectiverandomised trial to compare oral metoprolol with injectionsclerotherapy in cirrhosis (Clinical trial), 421

WESTROM, B. See TAGESSON, C, FRANZEN, L, et al.WHITEAR, W P. See WEBER, J N, CARMICHAEL, D J, et al.WHITEHOUSE, 1. See BEGLINGER, C, KOHLER, E, et al.WHITEHOUSE, J M A. See TROTrER, G A, MORGAN, G R, et al.WHITEWAY, j, and MORSON, B C: Elastosis in diverticular disease of

the sigmoid colon, 258WHITFIELD, P. See DANESH, B J Z, BURKE, M, et al.WHITFIELD, P F. See MELVILLE, R J, SULEIMAN, S i, et al.WHITWELL, H. See DAWSON, D J, and WHITWELL, HWIEDMANN, K H, TREJDOSIEWICZ, L K, GOODALL, A H, and THOMAS,H C: Analysis of the antigenic composition of liver specificlipoprotein using murine monoclonal antibodies, 510

WIENBECK, M. See SCHMITZ-MOORMANN, P, HIMMELMANN, G W, et al.WILLIAMS, C B. See BURMAN, J F, JENKINS, W J, et al.

See CHONG, S K F, BLACKSHAW, A J, et al.

WILLIAMS, L A. See HARRIES, A D, BROWN, R, et al.WILLIAMS, N S, EVANS, P, and KING, R F G J: Gastric acid secretionand gastrin production in the short bowel syndrome, 914

WILLIAMS, R. See AL-AGHBAR, M N A, NEUBERGER, J, et al.See CROSSLEY, I R, and WILLIAMS, RSee KEATING, J J, JOHNSON, R D, et al.See NEUBERGER, J, CHRISTENSEN, E, et al.See NEUBERGER, J, KENNA, G, et al.See WESTABY, D, MELIA, W M, et al.

WILLIAMSON, R C N. See ALLAN, A, BRISTOL, J B, et al.See CORFIELD, A P, COOPER, M J, et al.See RAINEY, J B, MAEDA, M, et al.

WILLOUGHBY, J M T. See BURFORD-MASON, A P, and WILLOUGHBY, J M T

WILSON, J A, and PHILLIPS, E M: Endoscopic retrieval of miniaturebattery (Letter), 215

WILSON, J S, BERNSTEIN, L, MCDONALD, C, TAIT, A, MCNEIL, D, andPIROLA, R C: Diet and drinking habits in relation to thedevelopment of alcoholic pancreatitis, 882

WILSON, M. See THOMPSON, D G, BINFIELD, P, et al.WINSTANLEY, P A, ELLIS, W R, HAMILTON, I, LINTOTr, D J, and AXON,A T R: Medium term complications of endoscopic biliarysphincterotomy, 730

WINTER, J W. See NOVICK, D M, ENLOW, R W, et al.WITHERS, M. See TZIPORI, S, ROBINS-BROWNE, R M, et al.WITTEBOL, P. See SMOUT, A J P M, BOGAARD, J W, et al.WOLKE, A M. See COHEN, L B, AMBINDER, E P, et al.WOOD, M L, FRENCH, M A, and FOULDS, I S: Protein-losing

enteropathy caused by systemic lupus erythematosus (Letter),758

WOOD, S M, KRAENZLIN, M E, ADRIAN, T E, and BLOOM, S R: Treatmentof patients with pancreatic endocrine tumours using a newlong-acting somatostatin analogue: symptomatic and peptideresponses, 438

WOODHEAD, S. See HARRIES, A D, BROWN, R, et al.WORNING, H. See ANDERSEN, B N, LARSEN, N-E, et al.WRIGHT, N A. See BRAMBLE, M G, ZUCOLOTO, S, et al.

See MIAZZA, B M, AL-MUKHTAR, M Y T, et al.See SAGOR, G R, GHATEI, M A, et al.See SAVAGE, A P, GORNACZ, G E, et al.

WRIGHT, R. See ARTHUR, M J P, TANNER, A R, et al.wu, P-C. See KUMANA, C R, NG, M, et al.

YAMADA, T. See MOGARD, M H, MAXWELL, V, et al.YANCOVITZ, S R. See NOVICK, D M, ENLOW, R W, et al.'Yellow-nail' syndrome with chylous ascites and intestinal lym-

phangiectasia (Case report), 1266YEOMANS, N D. See JONES, D B, and YEOMANS, N DYONK, B. See ORENSTEIN, M S, TAVITIAN, A, et al.YOSHIKAWA, T. See NISHIDA, K, SUGIURA, M, et al.YOUNG, G. See GILINSKY, N H, MEE, A S, et al.

ZACCARDELLI, E. See PAOLUZI, P, RICOTTA, G, et al.ZEEGEN, R. See FILIPE, M I, POTET, F, et al.ZENTLER-MUNRO, P L, FINE, D R, BATTEN, J c, and NORTHFIELD, T C:

Effect of cimetidine on enzyme inactivation, bile acid precipita-tion, and lipid solubilisation in pancreatic steatorrhoea due tocystic fibrosis, 892

ZEREGA, J. See ORENSTEIN, M S, TAVITIAN, A, et al.ZIMMERMAN, H. See BANK, S, ZIMMERMAN, H, et al.Zollinger-Ellison syndrome, development of cimetidine resistance

in (Case report), 1263ZUCOLOTO, S. See BRAMBLE, M G, ZUCOLOTO, S, et al.

1411

Abstracts IndexAbdominal tuberculosis in urban Britain, importance and preva-

lence among immigrants, A566Acetaldehyde metabolism, impairment in non-alcoholic liver dis-

orders, A563Acetate absorption in normal rat jejunum, mechanism of, A1109Acetylsalicyclic acid. See AspirinAchalasia, ambulatory oesophageal pH monitoring in, A1144

, surgical and bag dilatation treatment of, audit of, A541ACHESON, D W K, et al.: Dietary antioxidants, cytochrome P450, and

non-alcoholic pancreatitis, A577Adenoma-carcinoma sequence, colorectal, experimental supportdemonstrated with American but not with British histopatho-logical criteria, A573

Adenomata and colonic carcinoma, abnormal lectin binding in,A565

synchronous with colorectal cancer, Ca 19-9 antibody in, A564Adenosine triphosphatase, duodenal brush border membraneHCO--ATPase, implicated in HCOQ secretion, as expression ofalkaline phosphatase, AlllO

Adrenaline, endoscopic injection of, in bleeding peptic ulcers,A1136

ADRIAN, T E, et al.: Increased peptide YY release in patients withileal resection, A550

AFDHAL, N H, et al.: Ca 19-9 antibody in colorectal cancer andsynchronous adenomata, A564

AINLEY, C, et al.: Factors affecting suppression of cell mediatedimmunity in inflammatory bowel disease, A1122

Air and carbon dioxide in double contrast barium enema,

comparison of discomfort after, A582Albendazole, prophylactic, after operations for hydatid disease,

animal study, A1126Albumin, 51Cr-labelled, and cs1-antitrypsin in assessment of faecal

protein loss, A1112Alcohol abuse and HBV infection, synergic effect accentuating

liver disease or casual association?, A1124- and gallstones, acute pancreatitis related to, prospective

comparison of clinical and biochemical features of attack, A581-, blood levels, reduction by dietary lipid, mechanism of, A1113Alcoholic and non-alcoholic subjects with varices, gastrointestinal

bleeding in, short and long term prognosis, A575liver disease and autonomic neuropathy, A1139

Alcoholism, decreased red cell aldehyde dehydrogenase activity in,A1100

Aldehyde dehydrogenase activity of erythrocytes in health anddisease and as marker for hepatic aldehyde dehydrogenaseactivity, A1100

Alginate/antacid mixture in treatment of oesophagitis, comparisonwith antacid/dimethicone mixture, A574

Alkali acceleration of omeprazole absorption in Zollinger-Ellisonsyndrome, A1134

Alkaline secretion, luminal, in amphibian duodenum in vitro,effects of eicosanoids, A1110

Alkaline phosphatase, duodenal brush border membrane HCO3-ATPase, implicated in HCO3 secretion, as expression of, All10

ALLEN, J M, et al.: Omeprazole treatment results in elevation ofantral gastrin and reciprocal reduction in somatostatin concen-

trations, A558-, et al.: Presence, distribution and effects of neuropeptide Y in

the mammalian gut, A547AL MARDINI, H, et al.: Effect of methionine loading and endogenous

hypermethioninaemia on blood mercaptans in man, A568Alpha-adrenoreceptor-mediated inhibition by dopamine of human

isolated colonic muscle, A582ALSTEAD, E M, et al.: Comparison of conventional BSP kinetics with

single photon emission tomography, A563Aluminium, effect on bicarbonate secretion by isolated amphibian

gastroduodenal mucosa, A1150AMBROSE, N s, et al.: Patients with pruritis ani leak liquids from the

anal canal more readily than normal subjects, A1124Amino acid solutions in total parenteral nutrition, efficacy affected

by glycine content?, A1114acids, branched chain, plasma concentrations, increase after

high lipid parenteral feeds, investigation for possible use inportasystemic encephalopathy, A569

, plasma and CSF levels, effects of dietary protein,correlation with degree of encephalopathy, A1125

Ampicillin, effect on colonic salvage of carbohydrate, A1152Anal canal, abnormal leakage of liquids from, in pruritis ani, A1124

fissure, lateral subcutaneous sphincterotomy versus manualdilatation of anus under general anaesthetic for, A570- sphincter competence, analysis by measurement of analcompliance, A1123

ANDRE, c, et al.: Indirect evidence against the viral hypothesis inCrohn's disease in the Lyons area, A1155

ANDRE, F, et al.: Influence of human and murine giardiasis onintestinal permeability, A1142

ANDREWS, H A, and ALLAN, R N: How can the excess mortality fromCrohn's disease be reduced?. A1156

Androgen receptor, cytosolic, of classical type, identification in ratliver, A569

Angelchik prosthesis for reflux control, comparison with Nissenfundoplication, A555- -, late failures of, A1143Angiodysplasia, colonic, surgery in, outcome of, A1155Anorectal myectomy, value in treatment of chronic constipation,A1130

Antacid/dimethicone mixture in treatment of oesophagitis, com-parison with alginate/antacid mixture, A574

Antero-posterior rectopexy for solitary rectal ulcer syndromewithout overt rectal prolapse, A570

Antibiotics, single dose intravenous administration, emergence ofCl difficile and disturbance of faecal flora after, A1152

Antibodies, IgG subclass, to wheat gliadin in coeliac disease,A1113

monoclonal. See Monoclonal antibodiesstimulating gastric parietal cells, immunological forms of

duodenal ulcer produced by?, A1116to Campylobacterpyloridis, gastric, local, A1106

Antibody, monoclonal. See Monoclonal antibodyAntigen, carcinoembryonic. See Carcinoembryonic antigenAntigenic determinants of wheat protein in coeliac disease, A1108Antigens, liver cell, aberrant cellular reactivity to, and immunore-

gulatory defects in families of patients with autoimmune chronicactive hepatitis, A1100

, MHC, class I (HLA-A,B,C) and class II (HLA-DR),expression by colonic epithelium in intestinal schistosomiasis,A1120

Anti-inflammatory drugs, non-steroidal, and bleeding peptic ulcer,A1137

association with emergency peptic ulcer surgery,A1118

iatrogenic ilea! strictures caused by, pathology of,A542

ileocaecitis due to, A566Antioxidants, dietary, and cytochrome P450 induction in non-

alcoholic pancreatitis, A577Antipyrine and paracetamol clearance in chronic liver disease,

effect of acute and chronic propranolol administration, A1102ocx-Antitrypsin and 51Cr-albumin in assessment of faecal protein

loss, A1112Antiviral therapy, response rate to, factors determining, A568Antral gastritis, chronic, in duodenal ulcer, natural history and

response to misoprostol treatment, A1149, duodenal ulcer, and reflux oesophagitis, luminal and

mucosal pH in, A1117mucosa, gastrin content, and serum gastrin and pepsinogen I

412

Index to abstracts

in duodenal ulcer, influence of RP 40749 treatment, A1119Antro-antral reflexes, genesis in anaesthetised ferret, permissive

role for vagus nerves in, A1108Appendicectomy, emergency, surgeon's macroscopic diagnosis at,

relationship to subsequent histopathology, A565Arachidonic acid metabolism and leucocyte infiltration, as deter-mined by myeloperoxidase activity, in colon in model of IBD,A1148

ARKLE, s, and ARGENT, B E: Morphological and biochemical studieson rat pancreatic ducts maintained in tissue culture, A1132

ARMITAGE, N C, et al.: In vitro binding and in vivo localisation of an

anti CEA monoclonal antibody (C46), A1129ARMSTRONG, C P, et al.: Bile, infection and pancreatic duct integrity,A649

ARTHUR, M J P, et al.: Enhanced respiratory burst activity of Cpa.vum elicited hepatic macrophages compared with normalKupffer cells in the rat, A1103

Aspirin, absorption and effect on gastric mucosal electricalpotential difference, comparison with non-acetylated salicylate,A559

, gastric mucosal bleeding induced by, reduction by enprostil,A560

treatment, chronic, adaptation of gastric mucosa to, measuredby gastric microbleeding and cell exfoliation, A560

Atopic status and food intolerance in irritable bowel syndrome,A572

Atropine, dissociated effect on hypergastrinaemia induced bysingle or repeated doses of omeprazole, A1147

Autonomic neuropathy and alcoholic liver disease, A1139Azodisalicylate for treatment of active ulcerative colitis, A1157

of ulcerative colitis, clinical trial and assessment ofdrug disposition, A542

Azygous blood flow and hepatic venous pressures in cirrhosis,effect of long acting somatostatin analogue (SMS 201-995), A562

Baclofen (PCP-GABA), newly discovered activity as stimulant ofgastric acid secretion, clinical and experimental significance,A545

Bacterial contamination of upper small intestine in chronic renalfailure, A1140

BADR EL-DIN, s, et al.: Expression of MHC Class I (HLA-A,B,C)and Class II (HLA-DR) antigens by colonic epithelium in humanintestinal schistosomiasis, A1120

, et al.: T-lymphocyte subsets in the colonic mucosa of patientswith intestinal schistosomiasis, A1121

BAKER, P R, et al.: Long-term oral contraceptive use and serum totalcholesterol and total bile acids, A1127

BALASUBRAMANIAM, K, et al.: Compensatory increase in linguallipase activity and intragastric lipolysis in pancreatic steatorrhoeacaused by adult cystic fibrosis, A576

, et al.: Therapeutic potential of acid resistant fungal lipase inpancreatic steatorrhoea, A575

BALLANTYNE, K C, et al.: Flow cytometric analysis of the DNAcontent of gastric cancer, A1106

, et al.: Monoclonal antibody binding to primary and metasta-tic colorectal cancer, A1154

Balloons, hydrostatic, in dilatation of oesophageal strictures,A1143

versus bougies for dilatation of benign oesophageal stricture,trial of, A1136

BANNISTER, J i, et al.: Experimental support for a simple model ofdefecation, A1131

et al.: Faecal impaction in the elderly, A567et al.: Faecal incontinence in the elderly impacted patients,

A570, et al.: Urological abnormalities in patients with slow transit

constipation, A1131BANNISTER, P, et al.: Endocrine liver: identification of the classical

cytosolic androgen receptor in rat liver, A569

, et al.: Sex hormones and sex hormone binding globulin inpostmenopausal women with non-alcoholic liver cirrhosis, A570

BARCLAY, G R, and TURNBERG, L A: Influence of physical andpsychological stress on fluid and electrolyte absorption in thehuman jejunum in vivo, A554

BARDHAN, K D, et al.: Changing pattern of admissions for duodenalulcer in the Trent region, 1972-1983, A546

, et al.: Comparison of two different doses of omeprazoleversus ranitidine in duodenal ulcer healing, A557

, et al.: Enprostil versus ranitidine in duodenal ulcer, A1149Barium enema, double contrast, with carbon dioxide -and air,comparison of discomfort after, A582

radiology in gastro-oesophageal reflux disease, reappraisal of,A1103

BARTER, F, and TANNER, A R: Autonomic neuropathy and alcoholicliver disease, A1139

BARTER, s, et al.: Comparative studies of non-invasive investigationof Budd-Chiari syndrome, A568

BASILISCO, G, et al.: Do endogenous opioids regulate mouth-to-caecum transit time in man?, A551

BAUER, F E, et al.: Distribution and molecular forms of galanin inthe human intestine, A548

, et al.: Galanin in gut peptide secreting tumours and itsdiagnostic value in phaeochromocytomas, A1112

BENINI, L, et al.: Hyperenzymemia and molecular size distributionof trypsin and elastase 1 in the serum after ERCP and duringacute pancreatitis, A649

Beta-blockers in protection of upper gastrointestinal function fromdisturbance by stress, A559

BIANCHI PORRO, G, et al.: Comparison between three methods ofoesophageal pH recording in the diagnosis of gastro-oesophagealacid reflux, A1104

, et al.: Natural history of silent duodenal ulcer, A1145Bicarbonate, effect on efficacy of oral rehydration therapy in ratmodel of secretory diarrhoea, A1142

-secretion by isolated amphibian duodenum, effect of electricalfield stimulation, A111O

gastroduodenal mucosa, effect ofaluminium, A1150

, duodenal brush border membrane HCO3-ATPase,implicated in, as expression of alkaline phosphatase, AlllO

, gastroduodenal, amphibian, isolated, effect of sucral-fate, A1119

Bile acid profiles, duodenal, in patients with colorectal polyps,A1129

regimen, optimum, for rapid gall stone dissolution, A576transport, NA'-dependent, ileal, regulation of, A1113

acids and cholesterol, total, serum levels, and long-term oralcontraceptive use, A1127

-, faecal, excretion changes after promotion of coloniccancer by small bowel resection in rat, A564

involved in regulation of mouth-to-caecum transit time?,A1132

and bowels, effects of new wheat fibre product (Trifyba),A577

and infection, effects on rat pancreatic duct integrity, A649duct, common, calculi in, endoscopic removal in elderly,

cholecystectomy needed after?, A1158obstruction, ultrasound assessment for level, cause, and

tumour resectability, A1157strictures, benign, simulating malignant lesions at hilum

of liver, A561-reflux, role in oesophagitis and oesophageal stricture, A555

salts, Giardia interactions in vitro, A552-, uptake by Giardia lamblia, role in fat malabsorption?,

A1115BILGE, A, and ELDER, J B: Does gastric fundic pH or distension affect

ileal absorption?, A1108Biliary cirrhosis, primary, asymptomatic, enigma of, A1139

,-, in men, A567

1413

Index to abstracts

increased incidence of menstrual abnormalitiesand hysterectomy preceding, A1140

poor sulphoxidation status as factor in highincidence of adverse reactions to D-penicillamine therapy in,A561

prognosis in, importance of clinical staging for,A1126

small bowel disease in, A567prostheses, superiority of 10 French gauge straight compared

with 8 French gauge pigtail prostheses, A541tract, malignant stricture of, results of endoscopic stenting in,

Al 135BINGHAM, E A, et al.: Can dynamic liver scanning replace liver

biopsy in methotrexate patients?, AllOlBJARNASON, I, et al.: latrogenic ileocaecitis due to non-steroidal

anti-inflammatory drugs, A566, et al.: Intestinal imaging: comparison of "lIndium labelled

leucocytes and 99'Tc porphyrin, A553BLACKBURN, A, et al.: Long term use of cyclosporin A in patients

after liver grafting, A554Bleeding gastric varices, endoscopic sclerotherapy for, A1105

oesophageal varices. See Varices, oesophageal, bleedingpeptic ulcers and non-steroidal anti-inflammatory drugs,

A1137electrocoagulation with 7 FG bipolar probe in, trial

of, A1151endoscopic injection of adrenaline in, A1136

stress, gastric, prostaglandin E2 in prevention of, A1150varices, acute, control by vasopressin and vasopressin plus

nitroglycerin, trial of, A1137See also Haemorrhage

Blood alcohol levels, reduction by dietary lipid, mechanism of,A1113- flow, azygous, and hepatic venous pressures in cirrhosis,

effect of long acting somatostatin analogue (SMS 201-995), A562, hepatic, and portal hypertension in cirrhosis, reduction

by digoxin, A562, local, in canine colon, detection of, modified oxygen

electrode as probe for, A1128-, superior mesenteric artery, effect of glucose and

lactulose, A557- lipid changes related to dimethylhydrazine-induced colon

cancer in rats, A573mercaptans, effect of methionine loading and endogenous

hypermethioninaemia, A568- tests, occult, faecal, different, comparison of effects of lowresidue diet and purgation, A1128

BOLTON, R P, et al.: Defective neutrophil function in intestinallymphangiectasia, A550

Bombesin, inhibitory effect on pancreatic polypeptide secretion,evidence for, A1134

Bone marrow transplantation, acute graft versus host disease after,"'Indium granulocyte scanning in, A1122

BOUGHTON-SMITH, N K, et al.: Arachidonic acid metabolism andleukocyte infiltration, as determined by myeloperoxidase acti-vity, in a model of IBD, A1148

BOURKE, J B, et al.: Relationship between surgeon's macroscopicdiagnosis at emergency appendicectomy and the subsequenthistopathology, A565

Bowel preparation, rapid, for outpatient flexible sigmoidoscopy,A1156

See also Intestine(s)BRADBURY, W H, et al.: Preliminary evaluation of a modified PABA

test, A1134BRAIN, A J L, et al.: Slowing of gastric emptying after ingestion of

calcium ions in normal subjects: therapy for the dumpingsyndrome?, A549

Bran, wheat, dietary, in prevention of kwashiorkor-like liverchanges induced by elemental diet (Vivonex), A553

, low-phytate, inhibition of zinc absorption less than with

standard bran, A1114BREARLEY, s, et al.: Laparotomy: still a valuable investigation in

patients with bleeding from the intestine, A1128BRISTOL, J B, et al.: Increased crypt number is a feature of colonic

adaptation to jejunoileal bypass in rats, A572British Society of Gastroenterology: 46th Annual Meeting, AllO0

Spring Meeting, A541British Society of Gastroenterology early gastric cancer/dysplasia

survey, first 104 cases, Al 151Bromsulphthalein kinetics, conventional, in assessment of liver

disease, comparison with single photon emission tomography.A563

BROWN, A, et al.: Impaired gall bladder response to intravenouscacrulein in patients with coeliac disease, A580

BROWN, C P, et al.: Clinical and biochemical monitoring for evidenceof acute pancreatitis after ERCP (± sphincterotomy), A650

BROWN, S G, et al.: Focal necrosis in liver and a fibrosarcoma in ratsproduced by photodynamic therapy, A563

, et al.: Follow up of laser palliation for malignant dysphagia,A1144

BSP. See BromsulphthaleinBUAMAH, P K, et al.: An initial assessment of the value of serum

carbohydrate antigenic determinant (CA19-9) concentrations inpatients with pancreatic cancer, A577

Budd-Chiari syndrome, diagnosis by liver ultrasound and colloidscintigraphy, A568

long term prognosis of, A1127, non-invasive investigation of, comparative studies, A568

BULLIMORE, D w: Gastrointestinal bleeding in alcoholic and non-

alcoholic subjects with varices-short and long term prognosis,A575

Is active bleeding at time of initial endoscopy a badprognostic sign in variceal haemorrhage?, A575

BURKE, D A, and AXON, A T R: Adhesive E coli in ulcerative colitis,A1156

BURLAND, W L, et al.: SK&F 93574: preliminary evaluation of a

potent and long-acting parenteral H2-receptor antagonist in man,A1107

BURROUGHS, A K, et al.: Effect of a long acting analogue ofsomatostatin (SMS 201-995) on hepatic venous pressures andazygous blood flow in cirrhotics, A562

Ca 19-9 antibody in colorectal cancer and synchronous adenomata,A564- -, serum concentrations in pancreatic cancer, initial

evaluation of, A577Ca-50, detection in serum from patients with malignant liver

disease, Al 125Caerulein, intravenous, impaired gall bladder response in coeliac

disease to, A580Calcium activation of intestinal epithelial protein kinases, A1149

ions, ingestion of, slowing of gastric emptying after, measure-

ment in normal subjects, and possible use as therapy for dumpingsyndrome, A549

salt crystals, cholesterol nucleation on, morphology of, andcholesterol gall stone pathogenesis, A561

Calculi in common bile duct, endoscopic removal in elderly,cholecystectomy needed after?, A1158

CALLOW, D c, and LEATHARD, H L: Alpha-adrenoreceptor-mediatedinhibition by dopamine of human isolated colonic muscle, A582

Campylobacter pyloridis, antibodies to, gastric, local, A1106Campylobacter-like organisms, gastric, antibody response to, A544

in duodenal ulcer, pathogenic role of, A1117, presence in duodenal mucosa and effect of ulcer

treatment, A579Carbohydrate absorption, intestinal, regulation by 2 new selectiveenzyme inhibitors derived from deoxynojirimycin (BAY mlO99and o1248), A549

, colonic salvage of, effect of ampicillin, A1152

1414

Index to abstracts

malabsorption in postvagotomy diarrhoea, effect of codeineand loperamide, A1112

Carbomer, mucosal protective action on gastric mucus barrier,mechanism for, A1109

Carbon dioxide and air in double contrast barium enema,comparison of discomfort after, A582

Carbinoembryonic antigen, monoclonal antibody (C46) against, invitro binding and in vivo localisation of, A1129

Carcinogenesis, colonic, experimental, cell cycle kinetics during,A1154

, experimental, persisting susceptibility of healed colonicanastomoses to, A567

, gastric surgery as risk factor in, A553Carcinoid syndrome, effect of Ketanserin, clinical trial of, A556Carcinoma, colonic, and adenoma, abnormal lectin binding in,A565

, induced by dimethylhydrazine in rats, blood lipidchanges related to, A573

, -, promotion by small bowel resection in rat, changes infaecal bile acid excretion after, A564

signet ring cell, invasive behaviour of, structuralexplanation for, A574

, colorectal, and colorectal polyps, incidence in health care

district during first year of registration, A1129, and synchronous adenomata, Ca 19-9 antibody in,

AS641, ,cell line (HT29), effect of timed exposure to cytocidal

agents, A570cell-mediated immunity in, effect of surgery, A565frequency among first-degree relatives of patients with

cancer or polyps of large bowel, A1153human, tumour cell metabolism in vitro, inhibition by

monoclonal antibodies to ras-oncogene product, A1153, increased colonic prostaglandin E2 risk factor for?,

A1128liver metastases from, pre-operative diagnosis of,

prospective comparison of ultrasonic scanning and static anddynamic isotope imaging in, A1130

, primary and metastatic, monoclonal antibody bindingto, A1154- , -, survival in, influence of sialomucin at resection margin,A1129

, T lymphocyte subpopulations in blood, primary tumourand normal colonic mucosa in, Al154

, transition from adenoma to, experimental supportdemonstrated with American but not with British histopatho-logical criteria, A573

gastric, advanced, symptomatic, therapy in, A1106-, changes in mucus glycoprotein biosynthesis by cultured

human gastric mucosa in, A546DNA content of, flow cytometric analysis, A1106earlier diagnosis and improving prognosis in, A579early, and gastric dysplasia, BSG survey, first 104

cases, Al 151-1 -1,-, ,-1recognition of, pathologists'problems, AlSl

case for long term surveillance, A548risk after benign ulcer surgery, A1151

hepatocellular, cell line (PLC/PRF/5), monoclonal antibody(RFH-K1) directed against, in vitro and in vivo binding studieswith, A561

, oesophageal, evaluation by computed tQmography forintubation or operation, A1105-,- , squamous cell surface in, scanning electron microscopy

study, A574, of gastric stump, as separate clinical entity, evidence from

analysis of 799 patients, A579-, pancreatic, serum CA19-9 concentrations in, initial evalu-

ation of, A577, rectal, histological grading with multivariate analysis, A1153

, ulcerative colitis complicated by, peanut lectin binding anddysplasia in multicolonic biopsies in, A1122

Carcinoma-type mucus glycoprotein abnormalities in ulcerativecolitis and Crohn's disease demonstrated by lectin bindingchanges, A578

Cardiopulmonary bypass, pancreatitis after, related by mycoplas-ma infection?, A651

CAREY, L C: Misplaced pancreatic duct orifice as a cause of recurrentacute pancreatitis, A649

CARROLL, N J H, et al.: Secretin stimulates gastric mucus barrierthickness without increasing luminal mucus, A1109

CAYGILL, C P j, et al.: Gastric surgery as a risk factor in humancarcinogenesis, A553

Cell-mediated immunity in colorectal cancer, effect of surgery,

A565, suppression in inflammatory bowel disease, factors

affecting, A1122CHAPMAN, R w, et al.: Role of metronidazole in the management of

severe ulcerative colitis, A566CHEMELLO, L, et al.: Natural killer cell activity in acute viral

hepatitis, AllOtChenodeoxycholic and ursocholic acids, effects on gall bladder

emptying, A1124CHESNER, I M, et al.: High performance liquid chromatography of

plasma PABA-a sensitive assay for pancreatic exocrine dys-function, A1157

CHIARAMONTE, M, et al.: Does male sex predispose to the HBsAgcarrier state or to chronic liver disease?, A1139

, et at.: HBV infection and alcohol abuse: a synergic effectleading to a more severe liver disease or a casual association?,Al 124

Chloride secretion stimulated by prostaglandin E2 in guinea-pigisolated gastric mucosa, A1147

Cholangiopancreatography, retrograde, endoscopic. See ERCPCholangitis, acute, management of, and impact of endoscopic

sphincterotomy, A553and acute pancreatitis, A648sclerosing, and ulcerative colitis, peripheral blood T cell

subsets in, A1122Cholecystectomy, needed after endoscopic removal of common

bile duct stones in elderly?, A1158, subhepatic collection after, risk increased by drainage?,

A1158Cholecystogram, prolonged infusion, in early diagnosis of rightupper quadrant pain, A577

Cholecystokinin, molecular forms in plasma after ingestion of fat,A1 132

provocation test in suspected acalculous biliary pain, 31/2 yearsof clinical use, A1158

octapeptide-like material produced from larger forms duringcirculation, A1133

Choledocholithiasis, ultrasound screening in, assessment of, A1135Cholera toxin, intestinal secretion induced by, mediated via

neurogenic mechanism?, AlllCholesterol absorption by human gall bladder, A1132

and bile acids, total, serum levels, and long-term oralcontraceptive use, A1127

gall stone pathogenesis and morphology of cholesterolnucleation on calcium salt crystals, A561

Chromatin changes in premalignant colonic epithelium, A564Chromatography, liquid, high performance, of plasma PABA as

assay for pancreatic exocrine dysfunction, A1157Chyme in pancreatic steatorrhoea, composition and distribution of

lipids in, A652, ultracentrifuged, 2 new phases in, and solubilisation of

dietary fat, A651CICLITIRA, P J, et al.: Gluten free foods: do they cause symptoms in

coeliac patients?, A556, et al.: IgG subclass antibodies to wheat gliadin in patients

with coeliac disease, A1113

1415

General index

Cimetidine, acid reduction with, for short term treatment of acuteduodenal ulcer, comparison with sucralfate cytoprotection, A548

for short term treatment of gastric ulcer, comparison withsucralfate, A549-, large single night-time doses of, evaluation with continuous

24-hour ambulatory intragastric pH monitoring, A559, overnight response to, prediction of duodenal ulcer healing

from, A1150prognosis after perforated duodenal ulcer altered by?, A1118response to, in duodenal ulcer, affected by smoking?, A546versus sucralfate (histamine-2-antagonist versus cytoprotec-

tive agent) for short term treatment of prepyloric ulcer, A559Cirrhosis, biliary, primary, asymptomatic, enigma of, A1139

in men, A567increased incidence of menstrual abnormalities

and hysterectomy preceding, A1140poor sulphoxidation status as factor in high

incidence of adverse reactions to D-penicillamine therapy in,A561

prognosis in, importance of clinical staging for,A1126

small bowel disease in, A567childhood, Indian, severity of histological abnormality in,

poor correlation with liver copper content, A1138, hepatic haemodynamics in rat with, effect of portasystemic

shunting, A1102venous pressures and azygous blood flow in, effect of

long acting somatostatin analogue (SMS 201-995), A562intravariceal pressure in, effect of SMS 201-995, A1102of liver, non-alcoholic, sex hormones and sex hormone

binding globulin in postmenopausal women with, A570, portal hypertension and liver blood flow in, reduction by

digoxin, A562Cisapride inhibition of secretory action of serotonin in mammalian

small intestine, AllllCLASSEN, M, et al.: Omeprazole heals duodenal, but not gastric,

ulcers more rapidly than ranitidine, A558CLEMENTS, D, et al.: The Birmingham liver transplantation pro-gramme: our early experience, A1139

Clostridium difficile emergence and disturbance of faecal flora aftersingle dose intravenous antibiotic administration, A1152

Coagulation, impaired, liver biopsy in patients with, 'plugged' or

transvenous?, A1127Codeine and loperamide, effect on carbohydrate malabsorption inpostvagotomy diarrhoea, A1112

Coeliac disease, expression of abnormal c-myc oncogene product insmall intestinal epithelium in, A1143

gluten-free foods as cause of symptoms in, A556gluten-sensitive oral ulceration in absence of, A1137IgG subclass antibodies to wheat gliadin in, A1113impaired gall bladder response to intravenous caerulein

in, A580in teenagers, A551, inflammatory cell subpopulations in small intestinal

mucosa in, A1141macrophages in microenvironment of, A1140wheat protein in, antigenic determinants of, A1108

Colectomy, total, ileal absorption changes after, A543Colitis, collagenous, 5 cases of, A1152

ulcerative, active, azodisalicylate for treatment of, A1157adhesive E coli in, A1156and Crohn's disease, carcinoma-type mucus glyco-

protein abnormalities demonstrated by lectin binding changes in,A578

increased formation of leukotriene B4and sulphidopeptide-leukotrienes by rectal mucosa in, A542-I, -, and sclerosing cholangitis, peripheral blood T cell

subsets in, A1122_, ,1 azodisalicylate in treatment of, clinical trial andassessment of drug disposition, A542

-, -, complicated by carcinoma, peanut lectin binding anddysplasia in multicolonic biopsies in, A1122

in district general hospital, audit of, A1123severe, management of, role of metronidazole in, A566

Collagenous colitis, 5 cases of, A1152COLLINS, J S A, et al.: Long-term prognosis in childhood duodenal

ulcer, A547Colloid scintigraphy and liver ultrasound in diagnosis of Budd-

Chiari syndrome, A568Colo-anal anastomosis and mucosal proctectomy for chronic

radiation rectal injury, functional changes after, A1155Colon, adaptation to jejunoileal bypass in rats, increased cryptnumber in, A572

, anastomoses, healed, persisting susceptibility to experimen-tal carcinogenesis, A567

healing, peroperative assessment of colonic perfusionas predictor of, A571

and ileum, pH, comparison of effects of lactulose and lactitol,A1125

, arachidonic acid metabolism and leucocyte infiltration, as

determined by myeloperoxidase activity, in model of IBD,A1148

, benign and malignant diseases of, differentiation between,monoclonal antibodies to ras-oncogene product in, A1153

, canine, local blood flow in, detection of, modified oxygen

electrode as probe for, A1128carbohydrate salvage in, effect of ampicillin, A1152carcinogenesis, experimental, cell cycle kinetics during,

A1154, carcinoma of, and adenoma, abnormal lectin binding in,

A565induced by dimethylhydrazine in rats, blood lipid

changes related to, A573promotion by small bowel resection in rat,

changes in faecal bile acid excretion after, A564signet ring cell, invasive behaviour of, structural

explanation for, A574, distal, rat, apical membrane of, glucocorticoid (dexametha-

sone)-induced Na and K channels in, A1146, epithelial cells and resident macrophages, enhanced prosta-

glandin E2 production in inflammatory bowel disease by, A1121, epithelium, expression of MHC class I (HLA-A,B,C) and

class II (HLA-DR) antigens by, in intestinal schistosomiasis,A1120

premalignant, chromatin changes in, A564rat, ionic conductances in, segmental variability of,

A1148motility patterns in irritable bowel syndrome, investigation

with radiotelemetry, A1131-, mucosa of, in intestinal schistosomiasis, T-lymphocyte

subsets in, A1121, neoplasia of, promoted by super-efficient starch absorption?,

A554, permeability to 5'Cr-EDTA in inflammatory bowel disease,

A1123premalignancy in, detection of, A1122prostaglandin E2, increased, risk factor for colorectal

cancer?, A1128, proximal, steatorrhoea-decreased capitance of, experimen-

tal, segmental colonic function in, A1136Colonic angiodysplasia, surgery in, outcome of, A1155

muscle, isolated, human, x-adrenoreceptor-mediated inhibi-tion by dopamine, A582

Colorectal adenoma-carcinoma sequence, experimental supportdemonstrated with American but not with British histopatho-logical criteria, A573

carcinoma and polyps, incidence in health care district duringfirst year of registration, A1129

and synchronous adenomata, Ca 19-9 antibody in, A564cell line (HT29), effect of timed exposure to cytocidal

1416

Index to abstracts

agents, A570cell-mediated immunity in, effect of surgery, A565frequency among first-degree relatives of patients with

cancer or polyps of large bowel, A1153, human, tumour cell metabolism in vitro, inhibition by

monoclonal antibodies to ras-oncogene product, A1153, increased colonic prostaglandin E2 risk factor for?,

A1128, liver metastases from, pre-operative diagnosis of,

prospective comparison of ultrasonic scanning and static anddynamic isotope imaging in, A1130

, primary and metastatic, monoclonal antibody bindingto, A1154- -, survival in, influence of sialomucin at resection margin,A1129-, T lymphocyte subpopulations in blood, primary tumour

and normal colonic mucosa in, A1154function abnormalities in intractable constipation after

hysterectomy, A581in elderly constipated patients, A573

liver metastases, development delayed by razoxane (ICRF159), A572

polyps, duodenal bile acid profiles in patients with, A1129Computed tomography in evaluation of oesophageal carcinoma for

intubation or operation, A1105Constipation, chronic, value of anorectal myectomy in treatment

of, A1130colorectal function in elderly patients with, A573intractable, after hysterectomy, colorectal function abnor-

malities in, A581diagnosis and surgical management of, A1130

'simple', separation from spastic colon unjustified?, A571slow transit, absence of postprandial defaecation response in,

investigation of, A571urological abnormalities in, A1131

Contraceptives, oral, long-term use of, and serum total cholesteroland total bile acids, A1127

COOKE, T, et al.: Cell cycle kinetics during experimental coloniccarcinogenesis, A1154

Copper content of liver, poor correlation with severity of histo-logical abnormality in Indian childhood cirrhosis, A1138

CORCORAN, G D, et al.: Risk of gastric cancer after benign ulcersurgery, A1151

CORFIELD, A P, et al.: Hyperamylasaemia and pancreatic inflamma-tion after ERCP, A650

Corticosteroid maintenance therapy, chronic active hepatitis with,osteomalacia lacking in, A1126

Corynebacterium parvum, hepatic macrophages elicited with,enhanced respiratory burst activity compared with normalKupffer cells in rat, A1103

cox, J c, et al.: Balloons against bougies for dilatation of benignoesophageal stricture-a randomised prospective trial, A1136

CRAMPTON, J R, et al.: Effect of aluminium on bicarbonate secretionby isolated amphibian gastroduodenal mucosa, A1150

, et al.: Effect of electrical field stimulation on bicarbonatesecretion by isolated amphibian duodenum, AlllO

, et al.: Effect of sucralfate on isolated amphibian gastro-duodenal bicarbonate secretion, A1119

CRANFORD, c, et al.: Prospective evaluation of the Nissen fundopli-cation: effect on endoscopy, oesophageal pH and manometry,A555

Crohn's disease, abnormal presence of lactosylceramide detectedby thin layer chromatography in, A1156

and ulcerative colitis, carcinoma-type mucus glyco-protein abnormalities demonstrated by lectin binding changes in,A578

increased formation of leukotriene B4and sulphidopeptide-leukotrienes by rectal mucosa in, A542

, defective suppression in autologous mixed lymphocytereaction in, A544

excess mortality from, measures for reduction of, A1156fertility among women with, European study of, A543monocytes, inhibition of PgE2 secretion by salazopyrin

and prednisolone in, A1121- of small bowel, active, abnormal lactulose/rhamnose

permeability in, improvement by elemental diet, A1114strictureplasty in surgical management

of, A549patient education in, A1120perianal, surgical treatment for, dangers of, A1136serological studies in, A1120small bowel strictures in, methods of assessment, A578viral hypothesis in, indirect evidence from Lyons area

against, A1155CROWSON, M, et al.: Effect of timed exposure of cytocidal agents on

colorectal cancer (HT29) cells, A570CRUSE, J P, et al.: Experimental support for the colorectaladenoma-carcinoma sequence is provided when American butnot British histopathological criteria are used, A573

Crypt-villus axis of rat ileum in vitro, electrophysiological recordingalong, AllII

Cyclosporin A, long term use after liver grafting, A554Cystic fibrosis, adult, pancreatic steatorrhoca caused by, compen-

satory increase in lingual lipase activity and intragastric lipolysisin, A576

Cytochrome P450 induction and dietary antioxidants in non-

alcoholic pancreatitis, A577Cytocidal agents, effect of timed exposure on colorectal cancer

(HT29) cells, A570Cytoprotection, adaptive, mediation by prostaglandins, evidence

against, A1148Cytosolic androgen receptor of classical type, identification in rat

liver, A569

DANESH, B J Z, et al.: Non-acetylated salicylate is absorbed fasterand causes less disruption in the gastric mucosal electricalpotential difference than aspirin in man, A559

DAWSON, D J, et al.: Technetium-99m-sucralfate isotope scanning: a

new technique to detect active inflammatory bowel disease?,A578

DAWSON, K, et al.: Prospective randomised trial of Angelchikprosthesis versus Nissen fundoplication, A555

DAWSON, P M, et al.: Influence of sialomucin at the resection marginon survival of patients with colorectal cancer, A1129

Dazmegrel for gastric mucosal protection, A1107DEAKIN, M, et al.: Does smoking affect the response to cimetidine induodenal ulcer disease?, A546

et al.: Don't freeze pepsin!, A546et al.: Effect of Enprostil on 24 hour intragastric acidity and

nocturnal acid and pepsin output, A545, et al.: Treatment of duodenal ulcer by H2 blockade, large

single daily dose, how much and when?. A1120- et al.: Will overnight response to cimetidine predict healing of

duodenal ulcers?, AllS0DE DOMBAL, F T, et al.: BSG early gastric cancer/dysplasia survey:

the first 104 cases, A1151Defaecation response, postprandial, absence in slow transit consti-

pation, investigation of, A571? simple model of, experimental support for, A1131

DE LAZZARI, F, et al.: Are there immunological forms of duodenalulcer as a consequence of gastric parietal cell stimulatingantibodies?, A1116

Deoxynojirimycin, 2 new selective enzyme inhibitors (BAY mlO99and o1248) derived from, regulation of intestinal carbohydrateabsorption by, A549

DESMOND, H P, et al.: Identification of human progastrin, A1146DETrMAR, P w, et al.: A new role for polyacrylates in gastric mucosal

protection, A1107Diarrhoea of infancy, protected, autoimmune variant of, and loss

1417

Index to abstracts

of tolerance to self enterocytes, A544postirradiation, A573postvagotomy, carbohydrate malabsorption in, effect of

codeine and loperamide, A1112, pathophysiology of, new evidence for, A1118

secretory, efficacy of oral rehydration therapy in rat modelof, effect of bicarbonate, A1142

, , fluid and electrolyte transport in patient with, effect ofSMS 201-995, A1115

, toddler's, mouth-to-caecum transit time in, A1141Diarrhoeal disease, acute, in children, small round viruses in,A1141

Diet, elemental, improvement of abnormal lactulose/rhamnosepermeability in active Crohn's disease of small bowel by, A1114

(Vivonex), kwashiorkor-like liver changes induced by,prevention with dietary wheat bran, A552

, low residue, effect on different faecal occult blood tests,comparison with purgation, A1128

Diets, modular elemental and polymeric liquid, comparison ofeffects on growth, nitrogen balance and wastage, faecal residueand hepatic lipid in rats, Alll1

Digoxin reduction of portal hypertension and liver blood flow incirrhosis, A562

Diverticular disease promoted by super-efficient starch absorp-tion?, A1152

DNA content of gastric cancer, flow cytometric analysis of, A1106Dopamine, x-adrenoreceptor-mediated inhibition of human iso-

lated colonic muscle by, A582Dumping syndrome, possible use of slowing of gastric emptying

after ingestion of calcium ions as therapy for, A549DUNK, A, et al.: In vitro and in vivo binding studies with a

monoclonal antibody directed against the PLC/PRF/5 cell line,A561

Duodenum, amphibian, isolated, bicarbonate secretion by, effectof electrical field stimulation, AlllO

, luminal alkaline secretion in vitro, effects of eico-sanoids, AlllO

bile acid profiles in patients with colorectal polyps, A1129brush border membrane HCO3-ATPase, implicated in HCO3

secretion, as expression of alkaline phosphatase, AlllO, mucosa of, presence of Campylobacter-like organisms in, and

effect of ulcer treatment, A579, ulcer, acute, short term treatment of, comparison of

sucralfate cytoprotection and acid reduction with cimetidine for,A548-, -, admission pattern changes in Trent region, 1972-83,A546-, -, and gastric ulcer, healing of, comparison of omeprazole

with ranitidine for, A558, Campylobacter-like organisms in, pathogenic role of,

A1117-

1, , chronic antral gastritis in, natural history and responseto misoprostol treatment, A1149

, healing, comparison of 2 different doses of omeprazoleversus ranitidine in, A557

prediction from overnight response to cimetidine,A1150

, immunological forms produced by gastric parietal cellstimulating antibodies?, A1116

in childhood, long-term prognosis in, A547perforated, prognosis after, altered by cimetidine?,

A1118, prostaglandin E2 and leukotriene B4 production in,

effect of H2 receptor antagonists, A1119recurring, asymptomatic, natural history of, A1145reflux oesophagitis, and antral gastritis, luminal and

mucosal pH in, A1117, relapse in, due to persistent duodenal prostaglandin E2

deficiency?, A1150, response to cimetidine in, affected by smoking?, A546

-1 -, RP 40749 in treatment of, and influence on serum

gastrin, serum pepsinogen I and gastrin content of antralmucosa, A1119

, treatment by H2 blockade in large single daily dose,more effective with higher or earlier dosing?, A1120

,1- -, comparison between enprostil and ranitidine for,A1149

Dyspepsia in general practice, causes of, A580Dysphagia, malignant, laser palliation for, follow-up of, A1144Dysplasia and peanut lectin binding in multicolonic biopsies in

ulcerative colitis complicated by carcinoma, A1122-, gastric, and early gastric cancer, BSG survey, first 104 cases,

A1151-, -7 , -,recognition of, pathologists'problems, A1151

EDTA. See Ethylenediamine tetra-acetateEDWARDS, C A, et al.: Effect of somatostatin analogue SMS 201-995on fluid and electrolyte transport in a patient with secretorydiarrhoea, A1115

Eicosanoids, effects on amphibian duodenal luminal alkalinesecretion in vitro, All1O

Elastase 1 and trypsin, molecular size distribution in serum, andhyperenzymaemia after ERCP and during acute pancreatitis,A649

Electrical field stimulation, effect on bicarbonate secretion byisolated amphibian duodenum, A1110

Electrocoagulation with 7 FG bipolar probe in bleeding pepticulcers, trial of, A1151

Electrolyte and fluid absorption in jejunum in vivo, influence ofphysical and psychological stress, A554

transport in patient with secretory diarrhoea, effectof SMS 201-995, A1115

ELLIO-rr, E et al.: Effect of bicarbonate on efficacy of oralrehydration therapy in a rat model of secretory diarrhoea, A1142

Encephalopathy, degree of, correlation with effects of dietaryprotein on plasma and CSF levels, A1125

, portasystemic, investigation of increase in plasma branchedchain amino acid concentrations after high lipid parenteral feedsfor possible use in, A569

Endocrine cells of gastric corpus in patients treated with omepra-zole, stereological data on, A557

Endoscopic biopsies, upper GI, normal and abnormal, prosta-glandin E2 in, A560

haemostasis, new mechanical methods of (stitching, banding,clamping, ulcer removal), experimental studies, A1151

injection of adrenaline in bleeding peptic ulcers, A1136retrograde cholangiopancreatography. See ERCPsclerotherapy for bleeding gastric varices, A1105

, oesophageal ulceration after extravasation of sodiumtetradecyl sulphate and ethanolamine oleate during, A1105

sphincterotomy, impact in management of acute cholangitis,A553

-stenting in malignant stricture of biliary tract, results of,A1135

treatment of pyloric stenosis, A541ultrasonography in investigation of oesophageal strictures,

A1104Enema, water-soluble contrast, early postoperative, clinical im-

portance and complications, A1123Enprostil, effect on 24 hour intragastric acidity and nocturnal acidand pepsin output, A545

in treatment of duodenal ulcer, comparison with ranitidine,A1149

of gastric ulcer, comparison with ranitidine, A1149reduction of aspirin induced bleeding from gastric mucosa,

A560treatment, 24 hour intragastric acidity before and during,

A545

1418

Index to abstracts

Enteral nutrition and starvation, intestinal function during, A551Enteritis, radiation, established, natural history of, A556Enterochromaffin-like cell density in oxyntic mucosa, relation toplasma gastrin concentrations during inhibition of gastric acidseeretion in rat, A558- cells, gastric, demonstration of histamine content and

cholinergic nerve supply, A1145Enterocytes, rat, attachment of Giardia lamblia to, mediated by

trypsin-sensitive surface ligand, A1115Enterokinase generation of lysolecithin in trypsinogen, prophos-

pholipase A2, lecithin mixtures, and pathogenesis of acutenecrotising pancreatitis, A648

Enzyme induction in idiopathic pancreatitis, assessment of, A1133EPSTEIN, O, et al.: Importance of clinical staging for prognosis in

primary biliary cirrhosis, A1126ERCP and endoscopic sphincterotomy in acute pancreatitis,

prospective study, A541and sphincterotomy in management of acute pancreatitis,

A648(± sphincterotomy), evidence of acute pancreatitis after,

clinical and biochemical monitoring for, A650-, hyperamylasaemia and pancreatic inflammation after, A650

and pancreatitis induced by, role of protease inhibitor(aprotinin) in, A650-, hyperenzymaemia and molecular size distribution of trypsin

and elastase 1 in serum after, A649-, preoperative, in patients with pancreatic pseudocysts, A651Erythrocytes, aldehyde dehydrogenase activity, decrease in alco-

holism, A1100in health and disease and as marker for

hepatic aldehyde dehydrogenase activity, A1100Escherichia coli, adhesive, in ulcerative colitis, A1156ESSEN, H A VAN, et al.: Prostaglandin E2 in the prevention of gastric

stress bleeding, A1150Ethanol feeding, chronic, increased iron absorption in rats after,A1138

, influence on paracetamol hepatotoxicity, clinical and experi-mental studies, AllOl

Ethanolamine oleate and sodium tetradecyl sulphate extravasationduring endoscopic sclerotherapy, oesophageal ulceration after,AllOS

Ethylenediamine tetra-acetate, 51Cr-labelled, colonic permeabilityto, in inflammatory bowel disease, A1123

EUROPEAN COLLABORATIVE GROUP: European study of fertility amongwomen with Crohn's disease, A543

EVANS, D F, et al.: Effect of oesophageal pH sensors on patterns ofswallowing, A574

Faecal bile acid excretion changes after promotion of coloniccancer by small bowel resection in rat, AS64- flora, disturbance of, and emergence of Cl difficile after single

dose intravenous antibiotic administration, A1152impaction in elderly, A567incontinence, impaired recruitment of pelvic floor muscula-

ture by intra-abdominal pressure in, A1130- in elderly impacted patients, A570leucocytosis in acute gastroenteritis, A543occult blood tests, different, comparison of effects of low

residue diet and purgation, A1128protein loss, xl-antitrypsin and 51Cr-albumin in assessment of,

A1112FARTHING, M J G, et al.: Identification of Giardia surface antigensand their release during in vitro growth, A552

Fat absorption, micellar theory of, and identification of additionalaqueous phases, A576

, dietary, solubilisation of, and 2 new phases in ultracentri-fuged chyme, A651

ingestion, molecular forms of cholecystokinin in plasma after,A1132

malabsorption, role for bile salt uptake by Giardia lambliain?, A1115

Feeding and satiety, effect of ileal and intravenous lipid infusions,A1143-. See also Sham feedingFertility among women with Crohn's disease, European study of,A543

Fibrosarcoma and liver in rats, focal necrosis produced byphotodynamic therapy in, A563

FINAN, P j,, et al.: Prospective comparison of ultrasonic scanningand static and dynamic isotope imaging in the pre-operativediagnosis of liver metastases from colorectal cancer, A1130

FINE, D R, et al.: Composition and distribution of lipids in chymefrom patients with pancreatic steatorrhoea, A652

, et al.: How does dietary fat get into solution? Two newphases in ultracentrifuged chyme, A651

, et al.: Micellar theory of fat absorption may be only half thestory, A576

Fluid and electrolyte absorption in jejunum in vivo, influence ofphysical and psychological stress, A554

transport in patient with secretory diarrhoea, effectof SMS 201-995, A1115

FONDACARO, J D, et al.: Effects of protein kinase C activation onintestinal fluid transport and blood flow, AlllO

Food intolerance and atopic status in irritable bowel syndrome,A572

FOSTER, M E, and LEAPER, D J: Peroperative assessment of colonicperfusion as a predictor of anastomotic healing, A571

FOSTER, S N E, et al.: Mechanism for the mucosal protective action ofpolyacrylate on the gastric mucus barrier, A1109

FOZARD, J B 1, et al.: Peanut lectin binding and dysplasia inmulticolonic biopsies from patients with ulcerative colitis compli-cated by carcinoma, A1122

FREEMAN, J G, et al.: Haemodynamic responses to glypressin, A562FROST, R A, et al.: Discomfort after double contrast barium enema: a

prospective study of carbon dioxide and air for gas contrast,A582

Fundoplication. See Nissen fundoplication

Galanin in gut peptide secreting tumours and diagnostic value inphaeochromocytomas, A1112

in human intestine, distribution and molecular forms, A548Gall bladder contraction, induction by modified sham feeding,

atropine-sensitive CCK-independent mechanism for, A1133emptying, effects of chenodeoxycholic and ursocholic

acids, A1124pattern after dual phase meal, A1147

human, cholesterol absorption by, A1132impaired response to intravenous caerulein in coeliac

disease, A580stone dissolution, rapid, optimum bile acid regimen for, A576stones and alcohol, acute pancreatitis related to, prospective

comparison of clinical and biochemical features of attack, A581- -, cholesterol, pathogenesis of, and morphology of

cholesterol nucleation on calcium salt crystals, A561- , electrohydraulic lithotripsy of, in vitro study, A1135

GALLAND, R B, and SPENCER, J: Natural history of establishedradiation enteritis, A556

Gastric acid and pepsin output, nocturnal, and 24 hour intragastricacidity, effect of enprostil, A545

secretion, inhibition in rat, relation of plasma gastrinconcentrations and oxyntic mucosal ECL cell density during,A558

, overnight, effects of single nocturnal doses ofpirenzepine, A1116

stimulation of, newly discovered activity ofbaclofen (PCP-GABA) in, clinical and experimental signifi-cance, A545

antibodies to Campylobacter pyloridis, local, A1106

1419

Index to abstracts

Campylobacter-like organisms, antibody response to, A544carcinoma, advanced, symptomatic, therapy in, A1106

, changes in mucus glycoprotein biosynthesis by culturedhuman gastric mucosa in, A546

DNA content of, flow cytometric analysis, A1106earlier diagnosis and improving prognosis in, A579early, and gastric dysplasia, BSG survey, first 104 cases,

A1151-I -I, ,-1 recognition of, pathologists'

problems, A1151case for long term surveillance, A548

risk after benign ulcer surgery, Al151corpus, endocrine cells, in patients treated with omeprazole.

stereological data on, A557emptying, altered drug pharmacokinetics in smokers due to

effect on, A1144, slowing after ingestion of calcium ions, measurement in

normal subjects, and possible use as therapy for dumpingsyndrome, A549- enterochromaffin-like cells, demonstration of histamine con-

tent and cholinergic nerve supply, A1145fundic pH or distension, effect on ileal absorption, A1108juice, increased pepsin degradation of mucus by, in peptic

ulcer, measurement of, A1119mucosa, adaptation to chronic aspirin treatment measured by

gastric microbleeding and cell exfoliation, A560- -1, amphibian, secretion of adherent mucus gel in vitro by,A1109

, isolated, guinea-pig, chloride secretion stimulated byprostaglandin E2 in, A1147

mucosal bleeding induced by aspirin, reduction by enprostil,A560

damage and thromboxanes, A1145electrical potential difference, effects of non-acetylated

salicylate and aspirin compared, A559protection by thromboxane synthesis inhibitor

(dazmegrel), A1107role for polyacrylates in, A1107

mucus barrier, mucosal protective action of polyacrylate(carbomer) on, mechanism for, A1109

thickness, stimulation by secretin without increasein luminal mucus, A1109

parietal cell stimulating antibodies, immunological forms ofduodenal ulcer produced by?, A1116

stress bleeding, prostaglandin E2 in prevention of, A1150stump cancer as separate clinical entity, evidence from

analysis of 799 patients, A579surgery as risk factor in carcinogenesis, A553-, postprandial reactive hypoglycaemia after, effect of

glucomannan, A1118ulcer and duodenal ulcer, healing of, comparison of omepra-

zole with ranitidine for, A558, H2 receptor antagonists in, efficacy independent of

antisecretory effect, A1116, short term treatment of, comparison of sucralfate and

cimetidine for, A549treatment, comparison between enprostil and ranitidine

for, A1149varices, bleeding, endoscopic sclerotherapy for, A1105See also Intragastric

Gastrin and pepsinogen I, serum levels, and gastrin content ofantral mucosa in duodenal ulcer, influence of RP 40749treatment, A1119

, antral, elevation of, and reduction in antral and fundicsomatostatin after omeprazole treatment, A558

, plasma concentrations, relation to oxyntic mucosal ECL celldensity during inhibition of gastric acid secretion in rat, A558

Gastritis, antral, chronic, in duodenal ulcer, natural history andresponse to misoprostol treatment, A1149,-, duodenal ulcer, and reflux oesophagitis, luminal and

mucosal pH in, A1117Gastroduodenal bicarbonate secretion, amphibian, isolated, effect

of sucralfate, A1119mucosa, amphibian, isolated, bicarbonate secretion by, effect

of aluminium, A1150- , human, in vivo, evidence for neutral micro-climate

lining, A1117Gastroenteritis, acute, faecal leucocytosis in, A543Gastroenterology clinic, 2-year audit of, A579Gastrointestinal haemorrhage in alcoholic and non-alcoholic sub-

jects with varices, short and long term prognosis, A575, obscure, specialist investigation of, Al 154

hormone profile, postprandial, after intestinal glycosidaseinhibition, A1113

motility, physiological role for serotonin in?, A1146, postoperative, radiotelemetry study, A1142

peptide, tumours secreting, galanin in, and diagnostic value inphaeochromocytomas, A1112

tract, mammalian, presence, distribution and effects ofneuropeptide Y in, A547

, upper, endoscopic biopsies, normal and abnormal,prostaglandin E2 in, A560

function, protection by beta-blockers fromdisturbance by stress, A559

transit. See Mouth-to-caecum transitGastro-oesophageal reflux. See Reflux, gastro-oesophagealGastroplasty, vertical banded, in management of morbid obesity,

early and median term results, A1107Giardia bile salt interactions in vitro, A552

surface antigens, identification and release during in vitrogrowth, A552- lamblia attachment to rat enterocytes mediated by trypsin-

sensitive surface ligand, A1115- bile salt uptake, role in fat malabsorption?, A1115

Giardiasis, human and murine, influence on intestinal permeabil-ity, A1142

GIBBONS, C P, et al.: An analysis of anal sphincter competence bymeasurement of anal compliance, A1123

GIBSON, R N, et al.: Ultrasound assessment of bile duct obstruction:level, cause, and tumour resectability, A1157

Gilbert's syndrome, abnormal haem biosynthesis in, A564GIMSON, A E s, et al.: Randomised trial of vasopressin and

vasopressin plus nitroglycerin in the control of acute varicealhaemorrhage, A1137

Gliadin, wheat, IgG subclass antibodies to, in coeliac disease,A1113

GLISE, H, et al.: Short term treatment of acute duodenal ulcer: acomparison of cytoprotection with sucralfate and acid reductionwith cimetidine, A548

Glucagon-(1-21)-peptide applied locally to periampullary mucosa,relaxation of sphincter of Oddi by, A581

Glucocorticoid (dexamethasone), Na and K channels in apicalmembrane of rat distal colon induced by, A1146

Glucomannan, effect on postprandial reactive hypoglycaemia aftergastric surgery, A1118

Glucose and lactulose, effect on superior mesenteric artery bloodflow, A557

polymers and jejunal water absorption, A550Gluten-free foods as cause of symptoms in coeliac patients, A556Gluten-sensitive oral ulceration in absence of coeliac disease,A1137

Glycine content, efficacy of amino acid solutions in total parenteralnutrition affected by?, A1114

Glycoprotein abnormalities, carcinoma-type, in mucus in ulcera-tive colitis and Crohn's disease demonstrated by lectin bindingchanges, A578

Glycoproteins in mucus, biosynthesis by cultured human gastricmucosa, changes in gastric cancer, A546

Glycosidase inhibition, intestinal, postprandial gut hormone profileafter, A1113

1420

Index to abstracts

GLYNN, M j, et al.: High lipid parenteral feeds raise plasma branchedchain amino acid concentrations-a possible therapeuticapproach to portasystemic encephalopathy?, A569

Glypressin, haemodynamic responses to, A562GOODLAD, R A, et al.: Recombinant urogastrone-EGF can provide a

proliferative signal after small resection in parenterally fed rats,A1146

Graft ve'rsus host disease, acute, after bone marrow transplanta-tion, "'1Indium granulocyte scanning in, A1122

GRAINGER, S L, et al.: Endoscopic treatment of pyloric stenosis,A541

GRIFFIN, S M, et al.: Acid stable lipase in the treatment of pancreaticsteatorrhoea, A1158

GRUNDY, D, et al.: Permissive role for the vagus nerves in thegenesis of antro-antral reflexes in the anaesthetised ferret, A1108

Guar, hypocholesterolaemic dose of, intestinal transit times andstool output during intake of, A1115

GUERRERO, R, et al Toddler's diarrhoea-intestinal hurry?, A1141GUPTrA, S, and HODGSON, H i: Long term prognosis of Budd-Chiari

syndrome, A1127-, et al.: Is the pattern of idiopathic inflammatory disease

different in the elderly?, A544-, et al.: Partial hepatectomy enhances proliferation of ectopic-

ally sited liver cells in experimental animals, AllOlGUSTAFSEN, J, et al.: Clinical controlled trial of the effect of

Ketanserin in carcinoid syndrome, A556Gut. See Gastrointestinal

HABIB, N A, et al.: Detection of CA-SO in serum from patients withmalignant liver disease, A1125

, et al.: Expression of oncogene related proteins in humanmalignant liver neoplasms, A1126

, et al.: Use of monoclonal antibodies against ras-oncogeneproducts to inhibit the metabolism of human colorectal cancercells in vitro, A1153-, et al.: Use of monoclonal antibodies to ras-oncogene product

in the differentiation between benign and malignant diseases ofthe colon, A1153

HADJIS, N s, and BLUMGART, L H: Non-neoplastic bile duct stricturessimulating a malignant lesion at the hilum of the liver, A561

Haem biosynthesis, abnormal, in Gilbert's syndrome, A564Haemochromatosis, screening for, in UK, preliminary results,A1139

Haemorrhage, gastrointestinal. See Gastrointestinal haemorrhageintestinal, value of laparotomy for investigation of, A1128variceal, active bleeding at initial endoscopy in, bad

prognostic sign?, A575See also Bleeding

Haemostasis, endoscopic, new mechanical methods of (stitching,banding, clamping, ulcer removal), experimental studies, A1151

HAGEL, H-J, et al.: Adaptation of gastric mucosa to chronicacetylsalicylic acid treatment measured by gastric microbleedingand cell exfoliation in man, A560

HALL, C N, et al.: An attempt to resolve the nitrosamine controversyin hypochlorhydric subjects, A547

HALL, M 1, et al.: Low phytate wheat bran inhibits zinc absorptionless than standard bran, A1114

HALL, R I, et al.: Diagnosis and management of pancreatic ductinjuries in children: a report on four cases, A1133

HALLERBACK, B, et al.: Short term treatment of gastric ulcer-acomparison of sucralfate and cimetidine, A549

HALLE1T, M B, et al.: Intestinal tissue oxygen tension measurementusing a surface electrode, A1147

HALLIDAY, C E w, et al.: Bile salt uptake by Giardia lamblia: possiblerole in fat malabsorption, A1115

HALTER, F, et al.: Dissociated effect of atropine on hypergastri-naemia induced by single dose and repeated omeprazoletreatment, A1147

HAMILTON, i, et al.: Pancreatic enzyme synthetic rates in 'mild

chronic pancreatitis', A576HARPER, A A, et al.: Partial purification of pancreotone, A1134HARRISON, B J, and HUGHES, L E: Management and differential

diagnosis of perianal hidradenitis, A1131HARRISON, J D, et al.: Electrohydraulic lithotripsy of gall stones, an

in vitro study, A1135HASSAN, M, et al.: Peptic ulcer in Bangladesh-an endoscopic

survey, A1117HAWKEY, c 1, et al.: Adaptive cytoprotection: evidence against

mediation by prostaglandins, A1148, et al.: Gastric mucosal protection by a thromboxane synthesis

inhibitor, A1107, et al.: Reduction by enprostil of aspirin induced bleeding

from human gastric mucosa, A560HAYES, P C, and BOUCHIER, I A D: Effect of acute and chronic

propranolol administration on antipyrine and paracetamol clear-ance in chronic liver disease, A1102- , Prophylactic propranolol therapy in chronic liver

disease, A1103HAYNES, I G, et al.: Clinical importance and complications of the

early postoperative water-soluble contrast enema, A1123, et al.: Strictureplasty in the surgical management of small

bowel Crohn's disease, A549HEALY, M, et al.: Bacterial contamination in chronic renal failure,A1140

HEATON, N D, and HOWARD, E R: Anorectal myectomy: a valuabletreatment for chronic constipation, A1130

HELANDER, H F, et al.: Stereological data on endocrine cells of thegastric corpus in patients treated with omeprazole, A557

Hepatectomy, partial, enhancement of proliferation of ectopicallysited liver cells in experimental animals by, AllOl

Hepatic haemodynamics in cirrhotic rat, effects of portasystemicshunting, A1102- in pig, effect of SMS 201-995, A1102macrophages elicited with C parvum, enhanced respiratory

burst activity compared with normal Kupffer cells in rat, A1103- tight junctions, increased permeability to proteins in x-

naphthyl-isothiocyanate-treated rats, A1127-- venous pressures and azygous blood flow in cirrhosis, effect of

long acting somatostatin analogue (SMS 201-995), A562-. See also LiverHepatitis B surface antigen carrier state or chronic liver disease,male sex predisposed to?, A1139- virus infection and alcohol abuse, synergic effect

accentuating liver disease or casual association?, A1124, chronic active, autoimmune, immunoregulatory defects and

aberrant cellular reactivity to liver cell antigens in families ofpatients with, A1100

prognostic features in, A1140, with maintenance corticosteroid therapy,

osteomalacia lacking in, A1126, viral, acute, natural killer cell activity in, AllOl

Hepatocellular carcinoma cell line (PLC/PRF/5), monoclonalantibody (RFH-K1) directed against, in vitro and in vivo bindingstudies with, A561

Hepatocytes, ectopically sited, proliferation enhanced in experi-mental animals by partial hepatectomy, AllOl

See also Liver cell antigensHepatotoxicity, paracetamol, influence of ethanol on, clinical and

experimental studies, AllOlHepatotrophic factor, high molecular weight, from human serum,

partial purification of, A1124HETZEL, D J, et al.: Azodisalicylate in the treatment of ulcerative

colitis: a controlled clinical trial and assessment of drugdisposition, A542

Hexokinase activity and isoenzymic composition in rat liver andhepatic morphology, correlations between acute effects ofthioacetamide on, A1108

Hidradenitis, perianal, management and differential diagnosis of,A1131

1421

Index to abstracts

Hilar bile duct strictures, benign, simulating malignant lesions,A561

Histamine content and cholinergic nerve supply in gastric en-terochromaffin-like cells, demonstration of, A1145

H2 blockade in large single daily dose for treatment ofduodenal ulcer, more effective with higher or earlier dosing?,A1120

H2-receptor antagonists, effect on prostaglandin E2 andleukotriene B4 production in duodenal ulcer, A1119

in gastric ulcer, efficacy independent of antisecre-tory effect, A1116

See also Cimetidine; SK&F 93574Histocompatibility complex, major. See MHCHOPKINSON, G B, et al.: Serotonin, a physiological role in gastro-

intestinal motility?, A1146HOPMAN, w P M, et al.: Effect of glucomannan on postprandial

reactive hypoglycaemia after gastric surgery, A1118, et al.: Modified sham feeding induces gall bladder contraction

by an atropine-sensitive, CCK-independent mechanism, A1133HOSKING, s w, and JOHNSON, A G: Does Valsalva's manoeuvre cause

variceal bleeding?, A1144HOUGHTON, P w J, et al.: Early gastric cancer-the case for long term

surveillance, A548HOWARD, P, et al.: Effects of chenodeoxycholic and ursocholic acids

in gall bladder emptying, A1124, et al.: Is gall bladder emptying really exponential?, A1147

HOWDEN, c w, et al.: Effects of single nocturnal doses ofpirenzepine on overnight gastric secretion, A1116-, et al.: Efficacy of H2 receptor antagonists in gastric ulcer is

independent of antisecretory effect, A1116HUBSCHER, s, et al.: Biopsy findings in liver allograft rejection,A1127

HUI, w M, et al.: Humari gastric enterochromaffin-like cells:demonstration of histamine content and its cholinergic nervesupply, A1145

, et al.: Natural history of chronic antral gastritis in duodenalulcer and its response to treatment with prostaglandin El(misoprostol), A1149

, et al.: Pathogenic role of campylobacter-like organisms induodenal ulcer, A1117

HUTTON, D A, et al.: Measurement of increased pepsin degradationof mucus by gastric juice in peptic ulcer patients, A1119

Hydatid disease, prophylactic albendazole after operations for,animal study, A1126

Hyperamylasaemia and pancreatic inflammation after ERCP, A650and pancreatitis induced by ERCP, role of protease inhibitor

(aprotinin) in, A650Hypergastrinaemia induced by single or repeated doses of omepra-

zole, dissociated effect of atropine on, A1147Hypermethioninaemia, endogenous, and methionine loading,

effect on blood mercaptans, A568Hypertension, portal, and liver blood flow in cirrhosis, reductionby digoxin, A562

Hypochlorhydria, nitrosamine controversy in, results of investiga-tion, A547

Hypoglycaemia, reactive, postprandial, after gastric surgery, effectof glucomannan, A1118

Hysterectomy and menstrual abnormalities, increased incidencepreceding primary biliary cirrhosis, A1140

, intractable constipation after, colorectal function abnormali-ties in, A581

IBBOTSON, J P, et al.: Serological studies in Crohn's disease, A1120Ileal and intravenous lipid infusions, effect on feeding and satiety,A1143

reservoirs, relationship between mucosal structure andintestinal flora in, A565

Ileocaecitis, iatrogenic, due to non-steroidal anti-inflammatorydrugs, A566

Ileostomy output increased by neurotensin infusions, A551Ileum, absorption, changes after total colectomy, A543

- , effect of gastric fundic pH or distension, A1108and colon, pH, comparison of effects of lactulose and lactitol,

A1125, mucosa of, rabbit, influence of neuropeptide Y, A1137Na+-dependent bile acid transport, regulation of, A1113rat, in vitro, electrophysiological recording along crypt-villus

axis, Allll, resection, increased peptide YY release in patients with,

A550, strictures of, iatrogenic, caused by non-steroidal anti-

inflammatory drugs, pathology of, A542Immunity, cell-mediated, suppression in inflammatory bowel

disease, factors affecting, A1122Immunoglobulin G subclass antibodies to wheat gliadin in coeliac

disease, A1113Incontinence, faecal, impaired recruitment of pelvic floor muscula-

ture by intra-abdominal pressure in, A1130, in elderly impacted patients, A570

'"indium granulocyte scanning in acute graft versus host diseaseafter bone marrow transplantation, A1122

INGE, P M G, et al.: Giardia - bile salt interactions in vitro, A552-, et al.: Trypsin-sensitive surface ligand mediates attachment of

Giardia lamblia to rat enterocytes, AlliSIntestinal glycosidase inhibition, postprandial gut hormone profile

after, A1113lymphangiectasia, defective neutrophil function in, A550schistosomiasis, expression of MHC class I (HLA-A,B,C) and

class II (HLA-DR) antigens by colonic epithelium in, A1120- , T-lymphocyte subsets in colonic mucosa in, A1121

Intestine, large, as accessory organ of K excretion in chronic renalfailure, A571

, small, Crohn's disease of, active, abnormal lactulose/rhamnose permeability in, improvement by elemental diet,A1114

strictureplasty in surgical managementof, A549

disease of, in primary biliary cirrhosis, A567-, epithelium, coeliac, expression of abnormal c-myc

oncogene product in, A1143, lactitol absorption, A1114mammalian, secretory action of serotonin in, inhibition

by cisapride, Allll-, mucosa of, normal and coeliac, inflammatory cell

subpopulations in, A1141_, ,1 resection in parenterally fed rats, recombinant uro-gastrone-EGF as stimulant of proliferation after, A1146-, -, ,9 promotion of colonic cancer in rat by, changes in

faecal bile acid excretion after, A564, , strictures in Crohn's disease, methods of assessment,

A578-, _,1 upper, bacterial contamination of, in chronic renal

failure, A1140Intestines, bleeding from, value of laparotomy for investigation of,A1128

, carbohydrate absorption, regulation by 2 new selectiveenzyme inhibitors derived from deoxynojirimycin (BAY m1099and o1248), A549

, epithelial protein kinases, activation by calcium, A1149-, fluid transport and blood flow, effects of protein kinase Cactivation, AlllO

, function, and bile, effects of new wheat fibre product(Trifyba), A577

-, during starvation and enteral feeding, A551healing, and oxygen tension, effect of thromboxane synthe-

tase inhibitor (UK 38,485), A582human, galanin in, distribution and molecular forms, A548inflammatory disease, active, detection of, "9mTc-sucralfate

isotope scanning for, A578

1422

Index to abstracts

and smoking, A11SSarachidonic acid metabolism and leucocyte

infiltration, as determnined by myeloperoxidase activity, in colonin model of, A1148

colonic permeability to 51Cr-EDTA in, A11239 enhanced prostaglandin E2 production by colonic

epithelial cells and resident macrophages in, A1121idiopathic, pattern of, different in elderly?, A544osteoporosis in, Allil

-, -, suppression of cell mediated immunity in, factorsaffecting, A1122

, irritable bowel syndrome, colonic motility patterns in,investigation with radiotelemetry, A1131

food intolerance and atopic status in, A572gastro-oesophageal reflux in, A1104paroxysmal motor abnormalities evoked by

stress in, A556kinin action in, site of, AlllOlactase activity, neonatal, A552permeability, influence of human and murine giardiasis,

A1142, radio-imaging of, comparison of "'In-labelled leucocytes and

99mTc porphyrin for, A553, secretion induced by cholera toxin, mediated via neurogenic

mechanism?, Allll, tissue oxygen tension measurement using surface electrode,

A1147transit time. See Mouth-to-caecum transit time

times, and stool output during intake of hypocholester-olaemic dose of guar, AlllS

See also BowelIntragastric acidity, 24-hour, and nocturnal acid and pepsin output,

effect of enprostil treatment, A545before and during enprostil treatment, A545

pH monitoring, ambulatory, 24-hour, continuous, in evalua-tion of large single night-time doses of cimetidine, A559

Ionic conductances in rat colonic epithelium, segmental variabilityof, A1148

IRELAND, A, et al.: Azodisalicylate for the treatment of activeulcerative colitis, A1157

Iron absorption, increase after chronic ethanol feeding in rats,A1138

IVERS, M A, et al.: A two year audit of gastroenterology clinics, A579

JACYNA, M R, et al.: Cholesterol absorption by the human gallbladder, A1132

JANSEN, J B M J, and LAMERS, C B H W: Molecular forms ofcholecystokinin in human plasma after ingestion of fat, A1132

JASS, J R, and ATKIN, w S: Histological grading of rectal cancer: amultivariate analysis, A1153

Jaundice, obstructive, malignant, endoscopic and percutaneousprostheses in poor risk patients with, comparative trial, A1135

JAYARAJ, A P, et al.: Kwashiorkor-like liver changes induced by an

elemental diet can be prevented with dietary wheat bran, A552JAZRAWI, R, et al.: Optimum bile acid regimen for rapid gall stone

dissolution, A576Jejunoileal bypass, colonic adaptation in rats to, increased cryptnumber in, A572

Jejunum, fluid and electrolyte absorption in vivo, influence ofphysical and psychological stress, A554

rat, normal, acetate absorption in, mechanism of, A1109water absorption, and glucose polymers, A550

JENKINS, R T, et al.: Colonic permeability to 51Cr-EDTA ininflammatory bowel disease, A1123

JENKINS, S A, et al.: Effects of a long acting analogue ofsomatostatin (SMS 201-995) on hepatic haemodynamics in thepig and on intravariceal pressure in cirrhotic patients, A1102

, et al.: Effects of a long acting somatostatin analogue (SMS201-995) on the activity of the reticuloendothelial system in rats,

A1138, et al.: Effects of dietary protein on plasma and CSF amino

acid levels: correlation with the degree of encephalopathy,A1125

, et al.: Effects of portasystemic shunting on hepatic haemody-namics in the cirrhotic rat, A1102

JEPSON, M A, et al.: Correlations between the acute effects ofthioacetamide on hepatic morphology and on hexokinase activityand isoenzymic composition in the rat, A1108

JOHNSON, D A, et al.: Altered drug pharmacokinetics in smokers-an effect of smoking on gastric emptying, A1144

JOHNSTON, B J, et al.: Campylobacter-like organisms in the duodenalmucosa and the effect of ulcer treatment on their presence, A579

JONES, B J M, and SILK, D B A: Glucose polymers and jejunal waterabsorption, A550

, et al.: Hydrostatic balloon dilatation of oesophageal stric-tures, A1143

JONES, H w, et al.: An audit of ulcerative colitis in a district generalhospital, A1123

, et al.: Neurotensin infusions increase ileostomy output, A551JONG, A J L DE, et al.: Evidence for an inhibitory effect of bombesinon pancreatic polypeptide secretion in man, A1134

JUDD, D, et al.: Osteoporosis in patients with inflammatory boweldisease, Allll

KAN, K s, et al.: Increased permeability to proteins of hepatic tightjunctions in r-naphthyl-isothiocyanate-treated rats, A1127

KAPUR, B, et al.: Evaluation of large single night-time doses ofcimetidine using continuous 24-hour ambulatory gastric pHmonitoring, A559

KEATING, J J, et al.: Prognostic features in chronic active hepatitis,A1140

KEIGHLEY, M R B, and ALLAN, R N: Dangers of surgical treatment forperianal Crohn's disease, A1136

KELLEHER, D, et al.: Defective suppression in the autologous mixedlymphocyte reaction in patients with Crohn's disease, A544

KELLY, J, et al.: Inflammatory cell subpopulations in normal andcoeliac small intestinal mucosa, A1141

KENDALL, G P N, and THOMPSON, D G: Abnormal response todistension in oesophageal clearance disorders, A1103

KEOGH, J P, et al.: Effects of eicosanoids on amphibian duodenalluminal alkaline secretion in vitro, A1110

, et al.: Secretion of adherent mucus gel by amphibian gastricmucosa in vitro, A1109

Ketanserin, effect in carcinoid syndrome, clinical trial of, A556Kinin action in intestine, site of, A1110KLASS, H J, et al.: Small bowel disease in primary biliary cirrhosis,A567

KORDOSSIS, T, and GRIFFIN, G E: Faecal leucocytosis in acutegastroenteritis, A543

KUMAR, D, and WINGATE, D L: Irritable bowel is marked byparoxysmal motor abnormalities, A556

KUMAR, P J, et al.: The teenage coeliac, A551Kwashiorkor-like liver changes induced by elemental diet

(Vivonex), prevention with dietary wheat bran, A552

Lactase activity, intestinal, neonatal, A552Lactitol, effect on ileal and colonic pH, comparison with lactulose,A1125

, intestinal absorption and laxative threshold, A1114Lactosylceramide, abnormal presence detected in Crohn's diseaseby thin layer chromatography, A1156

Lactulose and glucose, effect on superior mesenteric artery bloodflow, A557

, effect on ileal and colonic pH, comparison with lactitol,A1 125

Lactulose/rhamnose permeability, abnormal, in active Crohn'sdisease of small bowel, improvement by elemental diet, A1114

1423

Index to abstracts

LAFERLA, G, et al.: Role of a protease inhibitor in ERCP inducedhyperamylasaemia and pancreatitis, A650

LAMERS, C B H W, et al.: Absorption of omeprazole in Zollinger-Ellison syndrome is accelerated by alkali, A1134

LANG, J, et al.: Pathology of iatrogenic ileal strictures caused bynon-steroidal anti-inflammatory drugs, A542

Laparotomy, value for investigation of intestinal bleeding, A1128LARCHER, v, et al.: Small round viruses in acute diarrhoeal disease in

children, A1141LARSSON, H, et al.: Relation of plasma gastrin concentrations and

oxyntic mucosal ECL cell density during inhibition of gastric acidsecretion in the rat, A558

Laser palliation for malignant dysphagia, follow-up of, A1144Lectin binding, abnormal, in colonic carcinoma and adenoma,A565

- changes, carcinoma-type mucus glycoprotein abnormali-ties in ulcerative colitis and Crohn's disease demonstrated by,A578

LEESE, T, et al.: Management of acute cholangitis and the impact ofendoscopic sphincterotomy, A553

, et al.: Use of fresh frozen plasma in the treatment of acutepancreatitis, A1157

LENNARD, T w J, et al.: Cholecystokinin provocation test insuspected acalculous biliary pain: three and a half years ofclinical use, A1158

, et al.: T lymphocyte subpopulations in the blood, primarytumour and normal colonic mucosa of patients with colorectalcarcinoma, A1154

Leucocytes, infiltration, as determined by myeloperoxidase acti-vity, and arachidonic acid metabolism in colon in model of IBD,A1148

"t"In-labelled, for intestinal imaging, comparison with 99mTcporphyrin, A553

Leucocytosis, faecal, in acute gastroenteritis, A543Leukotriene B4 and prostaglandin E2 production in duodenal ulcer,

effect of H2 receptor antagonists, A1119and sulphidopeptide-leukotrienes, increased formation

by rectal mucosa in Crohn's disease and ulcerative colitis, A542LEUNG, J W c, and CHUNG, s c S: Endoscopic injection of adrenaline

in bleeding peptic ulcers, A1136LEWIN, M R, et al.: Changes in blood lipids related to the presence of

dimethylhydrazine-induced colon cancer in rats, A573, et al.: Is increased colonic prostaglandin E2 a risk factor for

colorectal cancer?, A1128Lipase, acid stable, in treatment of pancreatic steatorrhoea, A1158

activity, lingual, and intragastric lipolysis, compensatoryincrease in pancreatic steatorrhoea caused by adult cysticfibrosis, A576

, fungal, acid resistant, therapeutic potential in pancreaticsteatorrhoea, A575

Lipid, dietary, reduction of blood alcohol level by, mechanism of,A1113

infusions, ileal and intravenous, effect on feeding and satiety,A1143

parenteral feeds, high, increase in plasma branched chainamino acid concentrations after, investigation for possible use inportasystemic encephalopathy, A569

Lipids, composition and distribution in chyme in pancreaticsteatorrhoea, A652-in blood, changes related to dimethylhydrazine-induced colon

cancer in rats, A573Lithotripsy, electrohydraulic, of gall stones, in vitro study, A1135Liver, aldehyde dehydrogenase activity, erythrocyte aldehydedehydrogenase activity in health and disease as marker for,AllO0

and fibrosarcoma in rats, focal necrosis produced by photo-dynamic therapy in, A563

biopsy in patients with impaired coagulation, 'plugged' ortransvenous?, A1127

blood flow and portal hypertension in cirrhosis, reduction by

digoxin, A562cell antigens, aberrant cellular reactivity to, and immunoregu-

latory defects in families of patients with autoimmune chronicactive hepatitis, AllO0

cells. See Hepatocyteschanges, kwashiorkor-like, induced by elemental diet

(Vivonex), prevention with dietary wheat bran, A552cirrhosis, non-alcoholic, sex hormones and sex hormone

binding globulin in postmenopausal women with, A570, copper content, poor correlation with severity of histological

abnormality in Indian childhood cirrhosis, A1138damage. See Hepatotoxicitydisease, alcoholic, and autonomic neuropathy, A1139

, assessment of, comparison of conventional BSP kineticswith single photon emission tomography in, A563

, chronic, antipyrine and paracetamol clearance in, effectof acute and chronic propranolol administration, A1102

, , or HBsAg carrier state, male sex predisposed to?,A1139

prophylactic propranolol therapy in, A1103hepatic steatosis and fibrosis in, ultrasound for detection

of, A569-, malignant, detection of CA-50 in serum from patients

with, A1125-disorders, non-alcoholic, impaired acetaldehyde metabolism

in, A563metastases from colorectal cancer, pre-operative diagnosis of,

prospective comparison of ultrasonic scanning and static anddynamic isotope imaging in, A1130

tumours, development delayed by razoxane(ICRF 159), A572

morphology and hexokinase activity and isoenzymic composi-tion in rat, correlations between acute effects of thioacetamideon, A1108

neoplasms, malignant, expression of ras-oncogene product in,using monoclonal antibodies, A1126

, rat, identification of classical cytosolic androgen receptor in,A569

scanning, dynamic, as replacement for liver biopsy inmethotrexate patients, A1101- transplantation, Birmingham programme, early experience

with, A1139- -, long term use of cyclosporin A after, A554

orthotopic, hepatic infarction after, A1138rejection after, biopsy findings in, A1127

ultrasound and colloid scintigraphy in diagnosis of Budd-Chiari syndrome, A568- in Budd-Chiari syndrome, comparison with CT scanning,

A568See also Hepatic

Loperamide and codeine, effect on carbohydrate malabsorption inpostvagotomy diarrhoea, A1112

LUCEY, M R, et al.: The enigma of asymptomatic primary biliarycirrhosis, A1139-, et al.: Primary biliary cirrhosis in men, A567Lymphangiectasia, intestinal, defective neutrophil function in,A550

Lymphocytes, autologous mixed lymphocyte reaction in Crohn'sdisease, defective suppression in, A544-. See also T cellLysolecithin generation by enterokinase in trypsinogen, pro-

phospholipase A2, lecithin mixtures, and pathogenesis of acutenecrotising pancreatitis, A648

MCCOLL, K E L, et al.: Abnormal haem biosynthesis in Gilbert'ssyndrome, A564

MCENTREE, G P, et al.: Cell-mediated immunity in colorectal cancer:the effect of surgery, A565

, et al.: Computed tomography evaluation of oesophageal

1424

Index to abstracts

carcinoma-intubate or operate?, A1105MCMAHON, M J, and MAYER, A D: Differentiation of acute pancreatitisfrom surgically correctable abdominal emergencies by peritoneallavage, A580

, et al.: Cholangitis and acute pancreatitis, A648Macrophages, hepatic, elicited with C parvum, enhanced respira-

tory burst activity compared with normal Kupffer cells in rat,Al 103

in microenvironment of coeliac disease, A1140Malabsorption, '4C-triolein test in diagnosis and management of,

experience with, A557Malignancy. See PremalignancyMALU, A o, et al.: Role of bile reflux in oesophagitis and

oesophageal stricture, A555MARCUS, S N, and HEATON, K w: Bile and bowels: the effects of a

new, concentrated wheat fibre product, A577Is 'simple constipation' a myth?, A571

MARTIN, D F, and TWEEDLE, D E F: Is cholecystectomy needed afterendoscopic removal of common bile duct stones in the elderly?,A1158

MASON, C H, and JEWELL, D P: Collagenous colitis: a report of fivecases, A1152

MATTHEWS, J, and COOKE, T: Changes in chromatin in premalignantcolonic epithelium, A564

, et al.: Detecting premalignancy in the colon, A1122MAITHEWSON, K, and RECORD, C O: Erythrocyte aldehyde dehydro-

genase activity in health and disease and its value as a marker forhepatic aldehyde dehydrogenase activity, Al100

, et al.: Impaired acetaldehyde metabolism in patients with nonalcoholic liver disorders, A563

MAXTON, D G, et al.: Intestinal function during starvation andenteral feeding, A551

MAXWELL, w j, et al.: Inhibition of PgE2 secretion by salazopyrinand prednisolone in normal and Crohn's disease monocytes,A1121

MAYBERRY, J F, et al.: An audit of surgical and bag dilatationtreatment of achalasia, A541

MAYER, A D, and MCMAHON, M J: Peritoneal fluid pool in acutepancreatitis-an enzyme sump?, A649-, et al.: Alcohol and gall stone related acute pancreatitis:

prospective comparison of clinical and biochemical features ofthe attack, A581

MAZZANTI, R, et al.: Increased iron absorption after chronic ethanolfeeding in rats, A1138

MEERWALDT, J H, and BLANKENSTEIN, M VAN: Postirradiation diar-rhoea, A573

Menstrual abnormalities and hysterectomy, increased incidencepreceding primary biliary cirrhosis, A1140

Mercaptans in blood, effect of methionine loading and endogenoushypermethioninaemia, A568

Mesenteric artery, superior, blood flow, effect of glucose andlactulose, A557

Methionine loading and endogenous hypermethioninaemia, effecton blood mercaptans, A568

Methotrexate therapy, dynamic liver scanning as replacement forliver biopsy in patients on, A1101

Metronidazole, role in management of severe ulcerative colitis,A566

MEYRICK THOMAS, J, et al.: Effect of treatment for one year withranitidine and of truncal vagotomy and pyloroplasty on intra-gastric pH, total and nitrate-reducing bacteria, and nitrite andN-nitroso compounds in patients with peptic ulcer, A547

MHC antigens, class I (HLA-A,B,C) and class II (HLA-DR),expression by colonic epithelium in intestinal schistosomiasis,A1120

Micellar theory of fat absorption and identification of additionalaqueous phases, A576

MIRAKIAN, R, et al.: Autoimmune variant of protracted diarrhoea ofinfancy: how is tolerance to self enterocytes lost?, A544

Misoprostol treatment, response of chronic antral gastritis in

duodenal ulcer to, A1149MITCHELL, K G, et al.: Preoperative ERCP in patients with

pancreatic pseudocysts, A651Monoclonal antibodies, expression of ras-oncogene product in

malignant liver neoplasms using, A1126to ras-oncogene product in differentiation between

benign and malignant diseases of colon, A1153in inhibition of metabolism of human

colorectal cancer cells in vitro, A1153See also Ca 19-9

antibody binding to primary and metastatic colorectal cancer,

A1154(C46) to CEA, in vitro binding and in vivo localisation

of, A1129(RFH-K1) directed against PLC/PRF/5 cell line, in vitro

and in vivo binding studies with, A561Monocytes, normal and in Crohn's disease, inhibition of PgE2

secretion by salazopyrin and prednisolone in, A1121MONSON, J R T, et al.: Does drainage increase the risk of subhepatic

collection following cholecystectomy? - a prospective study,A1158

MOORHEAD, R J, et al.: Duodenal bile acid profiles in patients withcolorectal polyps, A1129

MOREL, P, and ALEXANDER-WILLIAMS, J: Methods of assessment ofsmall bowel strictures in Crohn's disease, A578

MORGAN, A G, et al.: Comparison between enprostil and ranitidine inthe treatment of gastric ulceration and subsequent follow up

(interim report), A1149MORIARTY, K J, et al.: Cisapride inhibits the secretory action of

serotonin (5-HT) in mammalian small intestine, Allll, et al.: Influence of neuropeptide Y on rabbit ileal mucosa,

A1137, et al.: Is cholera toxin-induced intestinal secretion mediated

via a neurogenic mechanism?, AllllMORRIS, D L, et al.: Prophylactic chemotherapy after operations for

hydatid disease-an animal study, A1126, et al.: Ranitidine for stress ulceration: effect of bolus or

infusion administration, A1106, et al.: Study of postoperative gastrointestinal motility in man

using radiotelemetry, A1142Motor abnormalities, paroxysmal, evoked by stress in irritablebowel syndrome, A556

Mouth-to-caecum transit time in toddler's diarrhoea, A1141regulation of, bile acids involved in?, Al132

endogenous opioids involved in, A551Mucosa, antral, gastrin content, and serum gastrin and pepsinogen

I in duodenal ulcer, influence of RP 40749 treatment, A1119, colonic, in intestinal schistosomiasis, T-lymphocyte subsets

in, A1121, gastroduodenal, amphibian, isolated, bicarbonate secretion

by, effect of aluminium, A1150, human, in vivo, evidence for neutral micro-climate

lining, A1117, ileal, rabbit, influence of neuropeptide Y, A1137

Mucosa(l), gastric. See Gastric mucosa(l)Mucus, gastric. See Gastric mucus

gel, adherent, secretion by amphibian gastric mucosa in vitro,A1109

-glycoprotein biosynthesis by cultured human gastric mucosa,changes in gastric cancer, A546

, increased pepsin degradation by gastric juice in peptic ulcer,measurement of, Alll9

Mycoplasma infection, pancreatitis after cardiopulmonary bypassrelated to?, A651

Myeloperoxidase activity, leucocyte infiltration as determined by,and arachidonic acid metabolism in colon in model of IBD,A1148

MYLVAGANAM, K, et al.: Experience with a 14C triolein test in thediagnosis and management of malabsorption, A557

Myocardial infarction, oesophageal dysmotility after, A1104

1425

Index to abstracts

x-Naphthyl-isothiocyanate, increased permeability to proteins ofhepatic tight junctions in rats treated with, A1127

NASMYTH, D G, et al.: Changes in ileal absorption after totalcolectomy, A543-, et al.: Relationship between mucosal structure and intestinal

flora in ileal reservoirs, A565Natural killer cell activity in acute viral hepatitis, AllOlNELIS, G F, et al.: RP 40749 in the treatment of duodenal ulcer and

its influence on serum gastrin, serum pepsinogen I and gastrincontent of the antral mucosa, A1119

Neoplasia, colonic, promoted by super-efficient starch absorp-tion?, A554

Neoplasms of liver, malignant, expression of ras-oncogene productin, using monoclonal antibodies, A1126

NEOPTOLEMOS, J P, et al.: Endoscopic retrograde cholangio-pancreatography and sphincterotomy in the management ofacute pancreatitis, A648

Neuropathy, autonomic, and alcoholic liver disease, A1139Neuropeptide Y, influence on rabbit ileal mucosa, A1137

presence, distribution and effects in mammalian gut,A547

Neurotensin infusions, ileostomy output increased by, A551Neutrophils, defective function in intestinal lymphangiectasia,A550

Nissen fundoplication for reflux control, comparison with Angel-chik prosthesis, A555

prospective evaluation by effect on

endoscopy, oesophageal pH and manometry, A555Nitroglycerin plus vasopressin and vasopressin alone in control of

acute variceal haemorrhage, trial of, A1137Nitrosamine controversy in hypochlorhydria, results of investiga-

tion, A547NSAIDs. See Anti-inflammatory drugs, non-steroidalNutrition. See Enteral nutrition; Parenteral nutritionNutritional support, intravenous, peripheral, clinical efficacy of,Al 142

OAMAR, M i, et al.: Effect of glucose and lactulose on superiormesenteric artery blood flow in man, A557

Obesity, morbid, vertical banded gastroplasty in management of,early and median term results, A1107

O'BRIEN, C j, et al.: Immunoregulatory defects and aberrant cellularreactivity to liver cell antigens in families of patients withautoimmune chronic active hepatitis, et al.: A1100

O'BRIEN, J, et al.: Beta-blockers can protect human upper gastro-intestinal function from disturbance by stress, A559

O'BRIEN, J D, and BURNHAM, W R: Trial of the 7 FG bipolar probe inbleeding peptic ulcers, A1151

, et al.: Effect of codeine and loperamide on carbohydratemalabsorption in postvagotomy diarrhoea, A1112

Oddi, sphincter of. See Sphincter of OddiOesophageal varices. See Varices, oesophagealOesophagitis and oesophageal stricture, role of bile reflux in, A555

patterns of gastro-oesophageal reflux associated with, A1143reflux, duodenal ulcer, and antral gastritis, luminal and

mucosal pH in, A1117, treatment of, comparison of antacid/dimethicone mixture

and alginate/antacid mixture in, A574Oesophagus, carcinoma of, evaluation by computed tomography

for intubation or operation, A1105-,- ,1 squamous cell surface in, scanning electronmicroscopy study, A574

, clearance disorders, abnormal response to distension in,A1 103

distal, pH, normal profile, A555dysmotility after myocardial infarction, A1104pH monitoring, ambulatory, in achalasia, A1144

recording in diagnosis of gastro-oesophageal reflux, 3methods compared, A1104

sensors, effect on patterns of swallowing, A574strictures of, and oesophagitis, role of bile reflux in, A555

benign, dilatation of, gastro-oesophageal refluxaffected by?, A1105

-9 -,-, trial of balloons versus bougiesfor, A1136

dilatation of, hydrostatic balloons in, A1143investigation by endoscopic ultrasonography,

A1104peptic, treated by intermittent dilatation, com-

parison of medical and surgical reflux control in, A553, ulcer, after extravasation of sodium tetradecyl sulphate and

ethanolamine oleate during endoscopic sclerotherapy, A1105OLOMU, A, et al.: Poor sulphoxidation status in patients with

primary biliary cirrhosis could explain the high incidence ofadverse reactions to D-penicillamine therapy, A561

09MAHONEY, C, et al.: Antigenic determinants of wheat protein incoeliac disease, A1108

, et al.: Gluten sensitive oral ulceration in the absence ofcoeliac disease, A1137

Omeprazole absorption in Zollinger-Ellison syndrome, accelera-tion by alkali, A1134

, endocrine cells of gastric corpus in patients treated with,stereological data on, A557

for healing of duodenal and gastric ulcers, comparison withranitidine, A558

, hypergastrinaemia induced by single or repeated doses of,dissociated effect of atropine on, A1147

treatment, elevation of antral gastrin and reduction in antraland fundic somatostatin after, A558

, 2 different doses of, in duodenal ulcer healing, comparisonwith ranitidine, A557

Oncogene product, c-myc, abnormal, expression in coeliac smallintestinal epithelium, A1143

See also Ras-oncogeneOpioids, endogenous, involved in regulation of mouth-to-caecum

transit time?, A551Oral ulceration, gluten-sensitive, in absence of coeliac disease,A1137

Osteomalacia lacking in chronic active hepatitis with maintenancecorticosteroid therapy, A1126

Osteoporosis in inflammatory bowel disease, AllllOWEN, E R T c, et al.: Early and median term results of verticalbanded gastroplasty in the management of morbid obesity,A1107

Oxygen electrode, modified, as probe for detection of local bloodflow in canine colon, A1128

tension and intestinal healing, effect of thromboxane synthe-tase inhibitor (UK 38,485), A582

measurement in intestinal tissue using surface electrode,A1147

Oxyntic and parietal cell function, immediate effects of vagotomy,A1145

mucosal ECL cell density, relation to plasma gastrin concen-

trations during inhibition of gastric acid secretion in rat, A558

PABA in plasma, high performance liquid chromatography of, as

assay for pancreatic exocrine dysfunction, A1157test, modified, preliminary evaluation of, A1134

Pain, biliary, suspected acalculous, cholecystokinin provocationtest in, 31/2 years of clinical use, A1158

, right upper quadrant, early diagnosis by prolonged infusioncholecystogram, A577

PALMER, K R. et al.: Abdominal tuberculosis in urban Britain-anunderestimated clinical problem?, A566

Pancreas, exocrine dysfunction, high performance liquid chromato-graphy of plasma PABA as assay for, A1157

, inflammation of, and hyperamylasaemia after ERCP, A650Pancreatic carcinoma, serum CA19-9 concentrations in, initial

1426

Index to abstracts

evaluation of, A577- disease, benign and malignant, differentiation by testosterone

assay, A652-- , management of, alternative surgical procedures for,A652

-duct injuries in children, diagnosis and management in 4cases, A1133

integrity, rat, effects of bile and infection, A649- orifice, misplacement of, as cause of recurrent acute

pancreatitis, A649- ducts, rat, maintained in tissue culture, morphological and

biochemical studies on, A1132enzyme synthetic rates in 'mild chronic pancreatitis', A576polypeptide secretion, inhibitory effect of bombesin, evidence

for, A1134pseudocysts, preoperative ERCP in patients with, A651spasmolytic polypeptide, effect on sphincter of Oddi, A581steatorrhoea, acid stable lipase in treatment of, A1158

caused by adult cystic fibrosis, compensatory increase inlingual lipase activity and intragastric lipolysis in, A576- -, chyme in, composition and distribution of lipids in,A652

, therapeutic potential of acid resistant fungal lipase in,A575

Pancreatic Society of Great Britain and Ireland: 9th AnnualMeeting, A648

Pancreatitis, acute, and cholangitis, A648, differentiation from surgically correctable abdominal

emergencies by peritoneal lavage, A580, , ERCP and endoscopic sphincterotomy in, prospective

study, A541and sphincterotomy in management of, A648

,,evidence of, after ERCP (± sphincterotomy), clinicaland biochemical monitoring for, A650

fresh frozen plasma in treatment of, A1157hyperenzymaemia and molecular size distribution of

trypsin and elastase 1 in serum during, A649late follow up of patients, A651peritoneal fluid pool as sump for pancrea,tic enzymes

in, A6499 , recurrent, misplaced pancreatic duct orifice as cause of,

A649related to alcohol and gall stones, prospective

comparison of clinical and biochemical features of attack, A581- after cardiopulmonary bypass, related to mycoplasma infec-

tion?, A651and hyperamylasaemia induced by ERCP, role of protease

inhibitor (aprotinin) in, A650'chronic, mild', pancreatic enzyme synthetic rates in, A576idiopathic, enzyme induction in, assessment of, A1133

-, necrotising, acute, pathogenesis of, and lysolecithin genera-tion by enterokinase in trypsinogen, prophospholipase A2,lecithin mixtures, A648-, non-alcoholic, dietary antioxidants and cytochrome P450

induction in, A577Pancreotone, partial purification of, A1134Para-aminobenzoic acid. See PABAParacetamol and antipyrine clearance in chronic liver disease,

effect of acute and chronic propranolol administration, A1102-hepatotoxicity, influence of ethanol on, clinical and experi-

mental studies, AllOlParenteral nutrition, total, amino acid solutions in, efficacy

affected by glycine content?, A1114-1-, recombinant urogastrone-EGF as stimulant of

proliferation after small bowel resection in rats on, A1146Parietal and oxyntic cell function, immediate effects of vagotomy,A1145

PARK, R H R, et al.: Comparison of modular elemental and polymericliquid diets on growth, nitrogen balance, N wastage, faecalresidue and hepatic lipid in rats, A1112

PATIL, D H, et al.: Comparison of lactulose and lactitol on ileal andcolonic pH, A1125-, et al.: Intestinal absorption and laxative threshold oflactitol-a new hydrogenated derivative of lactose, A1114

Peanut lectin binding and dysplasia in multicolonic biopsies inulcerative colitis complicated by carcinoma, A1122

Pelvic floor musculature, impaired recruitment by intra-abdominalpressure in faecal incontinence, A1130

*, innervation damage in childbirth, obstetric factorsin, A581

PENAGINI, R, et al.: Are bile acids involved in the regulation ofmouth-to-caecum transit time in man?, A1132

, et al.: Does dilatation of benign oesophageal strictures affectgastro-oesophageal reflux?, A1105

, et al.: Intestinal transit times and stool output during intakeof a hypocholesterolaemic dose of guar in man, A1115

D-Penicillamine therapy, adverse reactions to, high incidence inprimary biliary cirrhosis, poor sulphoxidation status as factor in,A561

Pepsin and acid output, nocturnal, and 24 hour intragastric acidity,effect of enprostil, A545

degradation of mucus by gastric juice, increased, in pepticulcer, measurement of, A1119-, loss of activity after freezing of specimens, A546Pepsinogen I and gastrin, serum levels, and gastrin content of

antral mucosa in duodenal ulcer, influence of RP 40749treatment, A1119

Peptic ulcer, bleeding, and non-steroidal anti-inflammatory drugs,A1137

, - , electrocoagulation with 7 FG bipolar probe in,trial of, A1151

,-, endoscopic injection of adrenaline in, A1136effects of ranitidine treatment for one year, and truncal

vagotomy and pyloroplasty, on intragastric pH, total andnitrate-reducing bacteria, and nitrite and N-nitroso compoundsin, A547

, emergency surgery for, association with NSAIDs,A1118

, increased pepsin degradation of mucus by gastric juicein, measurement of, A1119

Peptide YY, increased release in patients with ileal resection, A550Peritoneal fluid pool in acute pancreatitis as sump for pancreaticenzymes, A649

lavage in differentiation of acute pancreatitis from surgicallycorrectable abdominal emergencies, A580

PESKAR, B M, et al.: Increased formation of leukotriene B4 andsulphidopeptide-leukotrienes by rectal mucosa of patients withCrohn's disease and ulcerative colitis, A542

Phaeochromocytomas, diagnostic value of galanin in, A1112Photodynamic therapy, focal necrosis in liver and fibrosarcoma in

rats produced by, A563Phytate, wheat bran low in, inhibition of zinc absorption less than

with standard bran, A1114PIASECKI, c, and LAKE, S: Modified oxygen electrode as a probe for

detecting local blood flow in canine colon, A1128Pirenzepine, single nocturnal doses of, effects on overnight gastric

secretion, A1116Plasma, fresh frozen, in treatment of acute pancreatitis, A1157-, molecular forms of cholecystokinin in, after ingestion of fat,A1132- PABA, high performance liquid chromatography of, as assay

for pancreatic exocrine dysfunction, A1157PLAYFORTH, M j, et al.: Pancreatitis after cardiopulmonary bypass

operations: is it related to mycoplasma infection?, A651POKORNY, c, et al.: Comparison of an antacid/dimethicone mixtureand an alginate/antacid mixture in the treatment of oesophagitis,A574

Polyacrylates, role in gastric mucosal protection, A1107-. See also CarbomerPolyps, colorectal, and colorectal cancer, incidence in health care

1427

Index to abstracts

district during first year of registration, A1129, duodenal bile acid profiles in patients with, A1129

or cancer, colorectal, frequency of large bowel cancer among

first-degree relatives of patients with, A1153PONZ DE LEON, M, et al.: Frequency of colorectal cancer among the

first-degree relatives of patients with cancer or polyps of thelarge bowel, A1153

, et al.: Incidence of colorectal cancer and polyps in a healthcare district: experience at one year of registration, A1129

Porphyrin, 99mTc-labelled, for intestinal imaging, comparison with.. In-labelled leucocytes, A553

Portal hypertension and liver blood flow in cirrhosis, reduction bydigoxin, A562

vein patency, ultrasound scanning in assessment of, A1125Portasystemic encephalopathy, investigation of increase in plasma

branched chain amino acid concentrations after high lipidparenteral feeds for possible use in, A569

shunting, effects on hepatic haemodynamics in cirrhotic rat,A1102

POSKIO-, K R, et al.: Right upper quadrant pain: the early diagnosisby prolonged infusion cholecystogram, A577

Potassium and sodium channels in apical membrane of rat distalcolon induced by glucocorticoid (dexamethasone), A1146

excretion in chronic renal failure, large intestine as accessory

organ of, A571POWELL-JACKSON, P, et al.: Diagnosis of Budd Chiari syndrome by

liver ultrasound and colloid scintigraphy, A568, et al.: Hepatic infarction after orthotopic liver transplanta-

tion, A1138Prednisolone and salazopyrin inhibition of PgE2 secretion innormal and Crohn's disease monocytes, A1121

Premalignancy, detection in colon, A1122Prepyloric ulcer, short term treatment of, cytoprotective agent

(sucralfate) versus histamine-2-antagonist (cimetidine) for, A559PRICE, A B, et al.: Pathologists' problems in the recognition of early

gastric cancer and gastric dysplasia, A1151PRICE, C A, et al.: Thromboxanes and gastric mucosal damage,A1145

Proctectomy, mucosal, with colo-anal anastomosis for chronicradiation rectal injury, functional changes after, A1155

Progastrin, human, identification of, A1146Propranolol administration, acute and chronic, effect on antipyrineand paracetamol clearance in chronic liver disease, A1102

therapy, prophylactic, in chronic liver disease, A1103Prostaglandin El. See Misoprostol

E2 and leukotriene B4 production in duodenal ulcer, effect ofH2 receptor antagonists, A1119

, colonic, increased, risk factor for colorectal cancer?,A1128

deficiency, duodenal, persistent, relapse in duodenalulcer due to?, A1150

in normal and abnormal upper GI endoscopic biopsies,A560

in prevention of gastric stress bleeding, AlS0production, enhanced, by colonic epithelial cells and

resident macrophages in inflammatory bowel disease, A1121secretion, inhibition by salazopyrin and prednisolone in

normal and Crohn's disease monocytes, A1121- stimulation of chloride secretion in guinea-pig isolated

gastric mucosa, A1147Prostaglandins, mediation of adaptive cytoprotection by, evidence

against, A1148Prostheses, endoscopic and percutaneous, in poor risk patients

with malignant obstructive jaundice, comparative trial, A1135Protease inhibitor (aprotinin), role in ERCP induced hyperamy-

lasaemia and pancreatitis, A650Protein, dietary, effects on plasma and CSF amino acid levels,

correlation with degree of encephalopathy, A1125loss, faecal, al-antitrypsin and 5'Cr-albumin in assessment of,

A1112

Protein kinase C activation, effects on intestinal fluid transport andblood flow, AlIlO

kinases of intestinal epithelium, activation by calcium, A1149Proteins, increased permeability of hepatic tight junctions to, in

x-naphthyl-isothiocyanate-treated rats, A1127Pruritis ani, abnormal leakage of liquids from anal canal in, A1124PUGH, S, et al.: Clinical and experimental significance of the newly

discovered activity of baclofen (PCP-GABA) as a stimulant ofgastric acid secretion, A545

, et al.: Is persistent duodenal prostaglandin E2 deficiency thecause of relapse in DU?, A1150-, et al.: Prostaglandin E2 in normal and abnormal upper GI

endoscopic biopsies, A560Purgation, effect on different faecal occult blood tests, comparison

with low residue diet, A1128Pyloric contractions, isolated, in fasted and fed human subjects,A1118

stenosis, endoscopic treatment of, A541

QUIGLEY, E M M, and TURNBERG, L A: Luminal and mucosal pH inpatients with duodenal ulcer, reflux oesophagitis and antralgastritis, A1117_, _: Neutral micro-climate lines human gastroduodenalmucosa in vivo, A1117

, et al.: ca-1-antitrypsin and 51-CR-albumin in the assessmentof faecal protein loss, A1112

RABY, N, et al.: Assessment of portal vein patency: value ofultrasound scanning, A1125

Radiation enteritis, established, natural history of, A556rectal injury, chronic, mucosal proctectomy with colo-anal

anastomosis for, functional changes after, A1155Radiotelemetry in investigation of colonic motility patterns in

irritable bowel syndrome, A1131study of postoperative gastrointestinal motility, A1142

Radiotherapy, diarrhoea after, A573RAIMES, S A, et al.: New evidence for the pathophysiology ofpostvagotomy diarrhoea, A1118

RAMAGE, J K, et al.: Oesophageal dysmotility after myocardialinfarction, A1104

Ranitidine for healing of duodenal and gastric ulcers, comparisonwith omeprazole, A558

for stress ulceration, effect of bolus or infusion administra-tion. A1106-in duodenal ulcer healing, comparison with omeprazole in 2

different doses, A557in treatment of duodenal ulcer, comparison with enprostil,

A1149of gastric ulcer, comparison with enprostil, A1149

treatment for one year, and truncal vagotomy and pyloro-plasty, effects on intragastric pH, total and nitrate-reducingbacteria, and nitrite and N-nitroso compounds in peptic ulcer,A547

RAO, S s C, et al.: Effect of ampicillin on the colonic salvage ofcarbohydrate, A1152

Ras-oncogene product, expression in malignant liver neoplasmsusing monoclonal antibodies, A1126

, monoclonal antibodies to, in differentiation betweenbenign and malignant diseases of colon, A1153

in inhibition of metabolism of humancolorectal cancer cells in vitro, A1153

RATHBONE, B j, et al.: Antibody response to gastric Campylobacter-like organisms, A544

et al.: Causes of dyspepsia in general practice, A580et al.: Local gastric antibodies to Campylobacter pyloridis,

A1 106Razoxane (ICRF 159), development of colorectal liver metastasesdelayed by, A572

READ, N W, et al.: Isolated pyloric contractions in fasted and fed

1428

Index to abstracts

human subjects, A1118Rectal ulcer, solitary, syndrome of, without overt rectal prolapse,

antero-posterior rectopexy for, A570Rectum, carcinoma of, histological grading with multivariate

analysis, A1153-, radiation injury, chronic, mucosal proctectomy with colo-

anal anastomosis for, functional changes after, A1155Red cells. See ErythrocytesREES, R G, et al.: Does glycine content affect the efficacy of amino

acid solutions in TPN?, A1114Reflux control, comparison of Angelchik prosthesis and Nissen

fundoplication for, A555-, medical and surgical, comparison in peptic oesophageal

stricture treated by intermittent dilatation, A553, Nissen fundoplication for, prospective evaluation by

effect on endoscopy, oesophageal pH and manometry, A555, gastro-oesophageal, affected by dilatation of benign

oesophageal strictures?, A1105barium radiology in, reappraisal of, A1103in irritable bowel syndrome, A1104oesophageal pH recording in diagnosis of, 3 methods

compared, A1104-, patterns associated with oesophagitis, A1143

oesophagitis. See Oesophagitis, refluxRehydration therapy, oral, efficacy in rat model of secretory

diarrhoea, effect of bicarbonate, A1142Renal failure, chronic, bacterial contamination of upper small

intestine in, A1140K excretion in, large intestine as accessory organ

of, A571Reticuloendothelial system activity in rats, effects of SMS 201-995,A1138

REY, J F, et al.: Effect of pancreatic spasmolytic polypeptide on thesphincter of Oddi, A581-, et al.: Relaxation of the sphincter of Oddi by glucagon-(1-21)-

peptide applied locally to the periampullary mucosa, A581REYNOLDS, J R, et al.: Investigation of colonic motility patterns in

the irritable bowel syndrome using radiotelemetry, A1131Rhamnose/lactulose permeability, abnormal, in active Crohn's

disease of small bowel, improvement by elemental diet, A1114RHODES, J M, et al.: Abnormal lectin binding in colonic carcinomaand adenoma, A565

, et al.: Carcinoma-type mucus glycoprotein abnormalities inulcerative colitis and Crohn's disease demonstrated by alteredlectin binding, A578

ROBERTS, G M, et al.: Alterations in mucus glycoprotein biosynthesisby cultured human gastric mucosa in gastric cancer, A546

ROE, A M, and MORTENSEN, N J MCC: Why do patients with slowtransit constipation have no postprandial defaecation response?,A571

, et al.: Diagnosis and surgical management of intractableconstipation, A1130

ROE, R, et al.: Healed colonic anastomoses remain susceptible toexperimental carcinogenesis, A567

ROOIJ, F W M DE, et al.: Regulation of ileal Na+-dependent bile acidtransport in man, A1113

ROSE, J D R, and SMITH, P M: Oesophageal ulceration afterextravasation of sodium tetradecyl sulphate and ethanolamineoleate during endoscopic sclerotherapy, A1105

ROWLAIT, c, et al.: Structural explanation for the invasive behaviourof signet ring cell carcinoma of the colon, A574

ROYCE, C M, et al.: Clinical efficacy of peripheral intravenousnutritional support, A1142

RP 40749 in treatment of duodenal ulcer and influence on serum

gastrin, serum pepsinogen I and gastrin content of antralmucosa, A1119

RUSSELL, R C G: Alternative surgical procedures for the manage-ment of pancreatic disease, A652

RUSTIN, G, et al.: Therapy in symptomatic advanced gastriccarcinoma, A1106

SACHDEV, G K, et al.: Peripheral blood T cell subsets in sclerosingcholangitis and ulcerative colitis, A1122

SADEK, s, et al.: Normal distal oesophageal pH profile, A555-, et al.: Patterns of gastro-oesophageal reflux associated with

oesophagitis, A1143Salazopyrin and prednisolone inhibition of PgE2 secretion innormal and Crohn's disease monocytes, A1121

SALEM, R R, et al.: Outcome of surgery in colonic angiodysplasia,A1155

, et al.: Specialist investigation of obscure gastrointestinalhaemorrhage, A1154

Salicylate, non-acetylated, absorption and effect on gastric mucosalelectrical potential difference, comparison with aspirin, A559

SANDERSON, I R, et al.: Improvement of abnormal lactulose/rhamnose permeability in active Crohn's disease of the smallbowel by an elemental diet, All14

SANDLE, G i: Glucocorticoid-induced Na and K channels in theapical membrane of rat distal colon, A1146-: Segmental variability of ionic conductances in rat colonicepithelium, A1148

, et al.: Large intestine as an accessory organ of K excretion inchronic renal failure, A571

SANDLE, L N, et al.: Methods to assess 'enzyme induction' inpatients with idiopathic pancreatitis, A1133

SANTANA, I A, et al.: Twenty four hour intragastric acidity beforeand during treatment with Enprostil, A545

SAVAGE, A P, et al.: Changes in faecal bile acid excretion followingpromotion of colonic cancer by small bowel resection in the rat,A564

SAVERYMUTrU, S H, et al.: "'Indium granulocyte scanning in acutegraft versus host disease after bone marrow transplantation,A1122

et al.: Ultrasound for the detection of hepatic steatosis andfibrosis in liver disease, A569

Schistosomiasis, intestinal, expression of MHC class I (HLA-A,B,C) and class II (HLA-DR) antigens by colonic epitheliumin, A1120

T-lymphocyte subsets in colonic mucosa in, A1121Scintigraphy, colloid, and liver ultrasound in diagnosis of Budd-

Chiari syndrome, A568, static and dynamic, in pre-operative diagnosis of liver

metastases from colorectal cancer, prospective comparison withultrasonic scanning, A1130

Sclerotherapy, endoscopic, for bleeding gastric varices, A1105, oesophageal ulceration after extravasation of sodium

tetradecyl sulphate and ethanolamine oleate during, A1105, prophylactic, of oesophageal varices, A1102

SCOnT, P D, and MCCLOY, R F: Immediate effects of vagotomy on

parietal and oxyntic cell function, A1145SCULLY, L J, et al.: Factors determining response rate to antiviral

therapy, A568Secretin stimulation of gastric mucus barrier thickness without

increase in luminal mucus, A1109SELDEN, A C, et al.: Partial purification of a high molecular weight

hepatotrophic factor from human serum, A1124SELLAR, R j, et al.: Barium radiology in gastro-oesophageal reflux

disease: a reappraisal, A1103Serotonin, physiological role in gastrointestinal motility?, A1146

, secretory action in mammalian small intestine, inhibition bycisapride, Allll

Serum from patients with malignant liver disease, detection ofCA-50 in, A1125

gastrin, serum pepsinogen I and gastrin content of antralmucosa in duodenal ulcer, influence of RP 40749 treatment,Al119

, human, high molecular weight hepatotrophic factor from,partial purification of, A1124

total cholesterol and total bile acids and long-term oralcontraceptive use, A1127

Sex hormones and sex hormone binding globulin in postmeno-

1429

Index to abstracts

pausal women with non-alcoholic liver cirrhosis, A570Sham feeding, modified, induction of gall bladder contraction by,

atropine-sensitive CCK-independent mechanism for, A1133SHANDALL, A, et al.: Effect of a thromboxane synthetase inhibitoron oxygen tension and intestinal healing, A582

SHEARER, M G, et al.: Late follow up of acute pancreatitis patients,A651

SHORVON, P j, et al.: Endoscopic ultrasonography in the investiga-tion of oesophageal strictures, A1104

Sialomucin, influence at resection margin on survival in colorectalcancer, A1129

Sigmoidoscopy, flexible, outpatient, rapid bowel preparation for,A1156

Signet ring cell carcinoma of colon, invasive behaviour of,structural explanation for, A574

SILVERMAN, S H, and KEIGHLEY, M R B: Rapid bowel preparation foroutpatient flexible sigmoidoscopy, A1156

SIMPSON, c J, et al.: Does cimetidine alter the prognosis afterperforated duodenal ulcer?, A1118

SIMSON, I N L, and NICHOLLS, R J: Antero-posterior rectopexy: a newtreatment for solitary rectal ulcer syndrome in patients withoutovert rectal prolapse, A570

SK&F 93574, preliminary evaluation of, A1107SLATER, N D, et al.: Prospective randomised study of ERCP and

endoscopic sphincterotomy in acute pancreatitis, A541SMART, H L, and MAYBERRY, J F: Patient education in Crohn's

disease, A1120.-, et al.: Ambulatory oesophageal pH monitoring in achalasia,A1144-, et al.: Gastro-oesophageal reflux in the irritable bowel

syndrome, A1104SMITH, M A, et al.: Food intolerance and atopic status in the irritablebowel syndrome, A572

Smokers, altered drug pharmacokinetics in, due to effect on gastricemptying, A1144

Smoking and inflammatory bowel disease, A1155-, response to cimetidine in duodenal ulcer affected by?, A546SMS 201-995, effect on fluid and electrolyte transport in patient

with secretory diarrhoea, A1115-, on hepatic haemodynamics in pig and intravariceal

pressure in cirrhotic patients, A1102--- venous pressures and azygous blood flow

in cirrhosis, A562, on reticuloendothelial system activity in rats,

A1138SNOOKS, S J, et al.: Obstetric factors in damage to the innervation of

the pelvic floor musculature in childbirth, A581Sodium and potassium channels in apical membrane of rat distal

colon induced by glucocorticoid (dexamethasone), A1146Sodium tetradecyl sulphate and ethanolamine oleate extravasation

during endoscopic sclerotherapy, oesophageal ulceration after,AllOS

Somatostatin analogues. See SMS 201-995-, antral and fundic, reduction in, and elevation of antral gastrin

after omeprazole treatment, A558SOMERVILLE, K w, et al.: Non-steroidal anti-inflammatory drugs and

bleeding peptic ulcer, A1137S0REIDE, O, et al.: Is gastric stump cancer a separate clinical entity?

Analysis of 799 patients, A579SPEER, A G, et al.: Randomised trial comparing endoscopic and

percutaneous prostheses in poor risk patients with malignantobstructive jaundice, A1135

, et al.: 10 French gauge straight biliary prostheses performsignificantly better than 8 French gauge pigtail prostheses, A541

Sphincter, anal, competence, analysis by measurement of analcompliance, A1123

of Oddi, effect of pancreatic spasmolytic polypeptide, A581, relaxation by glucagon-(1-21)-peptide applied

locally to periampullary mucosa, A581Sphincterotomy and ERCP in management of acute pancreatitis,

A648, endoscopic, and ERCP in acute pancreatitis, prospective

study, A541, impact in management of acute cholangitis, A552

-, subcutaneous, lateral, versus manual dilatation of anus undergeneral anaesthetic for anal fissure, A570

SPILLER, R c, et al.: Segmental colonic function in experimentalsteatorrhoea-decreased capitance of the proximal colon, A1136

SPRAGGS, C F, and BUNCE, K T: Prostaglandin E2 stimulates chloridesecretion in guinea-pig isolated gastric mucosa, A1147

SPRINGER, C j, and CALAM, j: Cholecystokinin octapeptide-likematerial is produced from larger forms during circulation in man,A1133

Squamous cell surface in oesophageal cancer, scanning electronmicroscopy study, A574

Starch absorption, super-efficient, colonic neoplasia promoted by?,A554

, , diverticular disease promoted by?, A1152Starvation and enteral feeding, intestinal function during, A551Steatorrhoea, experimental, capitance of proximal colon decreased

by, segmental colonic function in, A1136, pancreatic, acid stable lipase in treatment of, A1158-, caused by adult cystic fibrosis, compensatory increase

in lingual lipase activity and intragastric lipolysis in, A576,-, chyme in, composition and distribution of lipids in,

A652-, -, therapeutic potential of acid resistant fungal lipase in,A575

STELLON, A j, and WILLIAMS, R: Increased incidence of menstrualabnormalities and hysterectomy preceding primary biliary cirrhosis, A1140

, et al.: Lack of osteomalacia in chronic active hepatitis onmaintenance corticosteroid therapy, A1126

STEVENS, c, et al.: Abnormal presence of lactosylceramide detectedin Crohn's disease by thin layer chromatography, A1156

STEWART, C P, and TURNBERG, L A: Electrophysiological recordingalong the crypt-villus axis of rat ileum in vitro, Allll

STEWART, J, et al.: Abnormal c-myc oncogene product expression incoeliac small intestinal epithelium, A1143

STOKER, J, et al.: Results of endoscopic stenting in malignantstricture of the biliary tract, A1135

Stones. See CalculiStool output and intestinal transit times during intake of hypo-

cholesterolaemic dose of guar, A1115Stress bleeding, gastric, prostaglandin E2 in prevention of, A1150

, paroxysmal motor abnormalities evoked in irritable bowelsyndrome by, A556

, physical and psychological, influence 6n fluid and electrolyteabsorption in jejunum in vivo, A554-, protection of upper gastrointestinal function by beta-blockersfrom disturbance by, A559- ulceration, ranitidine for, effect of bolus or infusion adminis-

tration, A1106Strictureplasty in surgical management of small bowel Crohn's

disease, A549Sucralfate cytoprotection for short term treatment of acuteduodenal ulcer, comparison with acid reduction by cimetidine,A548 0

, effect on isolated amphibian gastroduodenal bicarbonatesecretion, A1119

for short term treatment of gastric ulcer, comparison withcimetidine, A549-, 99mTc-labelled, isotope scanning with, for detection of active

inflammatory bowel disease, A578versus cimetidine (cytoprotective agent versus histamine-2-

antagonist) for short term treatment of prepyloric ulcer, A559Sulphidopeptide-leukotrienes and leukotriene B4, increased forma-

tion by rectal mucosa in Crohn's disease and ulcerative colitis,A542

Sulphoxidation status, poor, in primary biliary cirrhosis as factor in

1430

Index to abstracts

high incidence of adverse reactions to D-penicillamine therapy,A561

SVEDBERG, L-E, et al.: Short term treatment of prepyloric ulcer-acytoprotective agent versus a histamine-2-antagonist, A559

SWAIN, c P, et al.: Experimental studies of new mechanical methodsof endoscopic haemostasis: stitching, banding, clamping, andulcer removal, A1151

Swallowing patterns, effect of oesophageal pH sensors, A574

T cell subpopulations in blood, primary tumour and normal colonicmucosa in colorectal carcinoma, A1154

subsets in colonic mucosa in intestinal schistosomiasis,A1121-- -, peripheral blood, in sclerosing cholangitis and

ulcerative colitis, A1122TAGGART, D, et al.: Differentiation between benign and malignant

pancreatic disease by testosterone assay, A652TALBOT, I c, et al.: Liver copper content correlates poorly with

severity of histological abnormality in Indian childhood cirrhosis,A1138

TANNER, A R, et al.: Screening for haemochromatosis in the UK:preliminary results, A1139

TAYLOR, R H, et al.: Postprandial gut hormone profile after intestinalglycosidase inhibition, A1113-, et al.: Razoxane (ICRF 159) delays appearance of colorectal

liver metastases, A572, et al.: Regulation of intestinal carbohydrate absorption in

man by two new selective enzyme inhibitors, A549TERRY, T R, et al.: Generation of lysolecithin by enterokinase in

trypsinogen, prophospholipase A2, lecithin mixtures, and itsrelevance to the pathogenesis of acute necrotising pancreatitis,A648

Testosterone assay in differentiation between benign and malig-nant pancreatic disease, A652

Thioacetamide, acute effects on hepatic morphology and hexo-kinase activity and isoenzymic composition in rat, correlationsbetween, A1108

THORNTON, J R, et al.: Does super-efficient starch absorptionpromote colonic neoplasia?, A554

, et al.: Does super-efficient starch absorption promotediverticular disease?, A1152

Thromboxane synthesis inhibitor. See DazmegrelThromboxane synthetase inhibitor (UK 38,485), effect on oxygen

tension and intestinal healing, A582Thromboxanes and gastric mucosal damage, A1145TOBIN, M v, and GILMORE, I T: Liver biopsy in patients with impaired

coagulation-which route?, A1127, et al.: Smoking and inflammatory bowel disease, A1155et al.: Ultrasonography in choledocholithiasis-a new look,

A1135Tomography, computed, in evaluation of oesophageal carcinoma

for intubation or operation, A1105-, single photon emission, in assessment of liver disease,

comparison with conventional BSP kinetics, A563Transplantation, bone marrow, acute graft versus host disease

after, "'Indium granulocyte scanning in, A1122- of liver, Birmingham programme, early experience with,A1139____- -, long term use of cyclosporin A after, A554

, orthotopic, hepatic infarction after, A1138-- , rejection after, biopsy findings in, A1127

TRAYNOR,-O J, et al.: Squamous cell surface in oesophageal cancer: ascanning electron microscopy study, A574

TREDGER, I M, et al.: Clinical and experimental studies of theinfluence of ethanol on paracetamol hepatotoxicity, AllOl

TREJDOSIEWICZ, L K, et al.: Macrophages in the microenvironmentof coeliac disease, A1140

TRIGER, D R, and JOHNSON, A G: Prophylactic sclerotherapy ofoesophageal varices: a preliminary report, A1102

4C-Triolein test in diagnosis and management of malabsorption,experience with, A557

Trypsin and elastase 1, molecular size distribution in serum, andhyperenzymaemia after ERCP and during acute pancreatitis,A649

Trypsin-sensitive surface ligand, attachment of Giardia lamblia torat enterocytes mediated by, A1115

Tuberculosis, abdominal, in urban Britain, importance and preva-lence among immigrants, A566

TUDOR, R G, et al.: Emergence of Clostridium difficile anddisturbance of faecal flora after single dose intravenous antibioticadministration, A1152

Tumours secreting gut peptide, galanin in, and diagnostic value inphaeochromocytomas, A1112

TURNER, N R, et al.: Decreased red cell aldehyde dehydrogenaseactivity in patients with alcoholism, AllO0

Ulcer. See under Duodenum; Gastric; Oesophagus; Peptic; Pre-pyloric; Rectal

Ulceration, oral, gluten-sensitive, in absence of coeliac disease,A1137

, stress, ranitidine for, effect of bolus or infusion administra-tion, A1106

Ultrasonography, endoscopic, in investigation of oesophagealstrictures, A1104

Ultrasound assessment of bile duct obstruction for level, cause, andtumour resectability, A1157- for detection of hepatic steatosis and fibrosis in liver disease,A569

, liver, and colloid scintigraphy in diagnosis of Budd-Chiarisyndrome, A568

in Budd-Chiari syndrome, comparison with CTscanning, A568

scanning in assessment of portal vein patency, A1125- in pre-operative diagnosis of liver metastases from

colorectal cancer, prospective comparison with static and dyna-mic isotope imaging, A1130

screening in choledocholithiasis, assessment of, A1135Urogastrone-EGF, recombinant, as stimulant of proliferation after

small bowel resection in parenterally fed rats, A1146Urological abnormalities in slow transit constipation, A1131Ursocholic and chenodeoxycholic acids, effects on gall bladder

emptying, A1124

Vagotomy, diarrhoea after. See Diarrhoea, postvagotomy, immediate effects on parietal and oxyntic cell function,

A1145-, truncal, and pyloroplasty, and ranitidine treatment for one

year, effects on intragastric pH, total and nitrate-reducingbacteria, and nitrite and N-nitroso compounds in peptic ulcer,A547

Vagus nerves, permissive role in genesis of antro-antral reflexes inanaesthetised ferret, A1108

VALORI, R M, et al.: Digoxin reduces portal hypertension and liverblood flow in patients with cirrhosis, A562

Valsalva's manoeuvre as cause of variceal bleeding, A1144Variceal haemorrhage, active bleeding at initial endoscopy in, bad

prognostic sign?, A575Varices, bleeding, acute, control by vasopressin and vasopressin

plus nitroglycerin, trial of, A1137gastric, bleeding, endoscopic sclerotherapy for, A1105gastrointestinal bleeding in alcoholic and non-alcoholic

subjects with, short and long term prognosis, A575-, oesophageal, bleeding, Valsalva's manoeuvre as cause of,A1143-, -, pressure measurement, relationship to portal pressure

and response to changes in intra-abdominal pressure, A562

1431

Index to abstracts

-, prophylactic sclerotherapy of, A1102pressure within, in cirrhotic patients, effect of SMS 201-995,

A1102VARMA, j. s, and SMITH, A N: Abnormalities of colorectal function in

intractable constipation after hysterectomy, A581et al.: Colorectal function in the elderly constipated, A573et al.: Functional changes after mucosal proctectomy with

colo-anal anastomosis for chronic radiation rectal injury, A1155Vasopressin and vasopressin plus nitroglycerin in control of acute

variceal haemorrhage, trial of, A1137

WALKER, A J, and DEWAR, E P: Emergency peptic ulcer surgery: an

association with NSAIDs, A1118WALSH, J P, et al.: Effect of H2 receptor antagonists on prostaglan-

din E2 and leukotriene B4 production in duodenal ulcer disease,A1119

WARD, D c, et al.: Earlier diagnosis and improving prognosis ofpatients with carcinoma of the stomach, A579

WARHURST, G, et al.: Activation of intestinal epithelial proteinkinases by calcium, A1149

, et al.: Site of kinin action in the intestine, AlllOWater absorption, jejunal, and glucose polymers, A550Water-soluble contrast enema, early postoperative, clinical im-

portance and complications, A1123WATSON, A: Randomised study comparing medical and surgical

reflux control in peptic oesophageal stricture treated by intermit-tent dilatation, A553

WATSON, A J M, et al.: Mechanism of acetate absorption in normalrat jejunum, A1109

WEAVER, L T, et al.: Neonatal intestinal lactase activity, A552WEAVER, M, et al.: Lateral subcutaneous sphincterotomy versus

manual dilatation of the anus performed under general anaes-thetic for anal fissure, A570

WELCH, I MCL, and READ, N w: Effect of ileal and intravenous lipidinfusions on feeding and satiety in humans, A1143

, et al.: How does dietary lipid lower blood alcohol levels?,A1113

WESTABY, D, et al.: Oesophageal varix pressure measurement: therelationship to portal pressure and the response to changes inintra-abdominal pressure, A562

Wheat bran. See Bran, wheatfibre product, new (Trifyba), effects on bile and bowels, A577gliadin. See Gliadin, wheatprotein in coeliac disease, antigenic determinants of, A1108

WILKES, J M, et al.: Duodenal brush border membrane HCO3-ATPase, implicated in HCOj secretion, is an expression ofalkaline phosphatase, AlllO

WILLIAMSON, B W A, et al.: Cholesterol gall stone pathogenesis:morphology of cholesterol nucleation on calcium salt crystals,A561

WOLVERSON, R L, and TEMPLE, I G: Late failures of the Angelchikprosthesis, A1143

WOMACK, N R, et al.: Impaired recruitment of the pelvic floormusculature by intra-abdominal pressure in faecal incontinence,A1130

YASSIN, Y M, et al.: Endoscopic sclerotherapy for bleeding gastricvarices, A1105

YIU, c Y, et al.: Comparison of low residue diet and purgation ondifferent faecal occult blood tests, A1128

Zinc absorption inhibited less by low-phytate wheat bran than bystandard bran, A1114

Zollinger-Ellison syndrome, omeprazole absorption in, accelera-tion by alkali, A1134

1432

Journal of the British Societyof Gastroenterology

VOLUME TWENTY SIX1985

EDITOR

J J MISIEWICZ

BOOK REVIEW EDITOR

D L WINGATE

Editorial CommitteeA ALLEN

D J ALLISON

E L BLAIR

S R BLOOM

R M CASE

R COCKEL

P B COTTON

A G COX

G P CREAN

J FIELDING

R C HEADING

I D HILL

H J F HODGSON

D P JEWELL

A G JOHNSON

R M KIRK

A S MCNEISH

T J PETERS

A B PRICE

N READ

I TAYLOR

G T WILLIAMS

ROGER WILLIAMS

K G WORMSLEY

EDITOR British Medical JournalSHIRLEY MCGEALEY (Technical Editor)

BRITISH MEDICAL ASSOCIATIONTAVISTOCK SQUARE * LONDON WC1

ContentsNo 1, JANUARY 1985

PageLeading article: The delta agent comes of age H C THOMAS ........................................................................ 1Liver and biliary: Infection with the delta agent in children P FARCI, C BARBERA, C NAVONE, F BORTOLOTTI, P VAJRO, N

CAPORASO,AVEGNENTE, N ANSALDI, M RIZZETTO, P TOLENTINO, AND R CALZIA .................................................. 4Hepatic cirrhosis in young adults: association with adolescent onset of alcohol and parenteral heroin abuse D MNOVICK, R W ENLOW, A M GELB, R J STENGER, M FOTINO, J W WINTER, S R YANCOVITZ, M D SCHOENBERG, AND M J KREEK 8Pharmacology of propranolol in patients with cirrhosis and portal hypertension M J P ARTHUR, A R TANNER,C PATEL, RALPH WRIGHT, A G RENWICK, AND C F GEORGE.............................................................................. 14Mononuclear cell complement receptor blockade in primary biliary cirrhosis M N A AL-AGHBAR, J NEUBERGER,ROGER WILLIAMS, AND A L W F EDDLESTON ......................... ..................................................................... 20Plasma glutathione S-transferase measurements after paracetamol overdose: evidence for early hepatocellular

damageGJBECKETT,B JCHAPMAN, E H DYSON, AND J D HAYES ..................................................................... 26Effect of Rowachol on biliary lipid secretion and serum lipids in normal volunteers OTTMAR LEISS AND KLAUS VONBERGMANN ...................................................................................................................... 32Profiles of bile acids and their glucoronide and sulphate conjugates in the serum, urine and bile from patientsundergoing bile drainage H TAKIKAWA, T BEPPU, AND Y SEYAMA................................................................... 38Incidence of colorectal cancer in protocolitis: a retrospective study of 959 cases over 40 years z MARATKA, J

NEDBAL,JKOCIANOVA,J HAVELKA, J KUDRMANN, AND J HENDI ..................................................................... 43Alimentary tract and pancreas: Concentration of selenium in plasma and erythrocytes during total parenteralnutrition in Crohn's disease S JACOBSON AND L-O PLANTIN. ......................................................................... 50Histological diagnosis of chronic inflammatory bowel disease in childhood S K F CHON, A J BLACKSHAW, S BOYLE,

CB WILLIAMS, AND J A WALKER-SMITH ............................... .................................................................... 55Isolation of intestinal mononuclear cells: factors released which affect lymphocyte viability and function P RGIBSON, A HERMANOWICZ, H J J VERHAAR, D J P FERGUSON, A LOPEZ BERNAL, AND D P JEWELL ....... ......................... 60Methane excretion in man - a study of breath, flatus and faeces LINDA F MACKAY, M A EASTWOOD, ANDWGBRYDON ...................................................................................................................... 69Nufenoxole, a new antidiarrhoeal agent, inhibits fluid secretion in the human jejunum K J MORIARTY, D D KROLSTON, M J KELLY, M SHIELD, AND M L CLARK........................................................................................ 75Intraepithelial lymphocytes of human gut: isolation, characterisation and study of natural killer activity NADIE

CERF-BENSUSSAN,DELPHINE GUY-GRAND, AND C GRISCELLI .......................................................................... 81Influence of somatostatin and bombesin on plasma enteroglucagon and cell proliferation after intestinalresection in the rat G R SAGOR, M A GHATEL, D J O'SHAUGHNESSY, M Y T AL-MUKHTAR, N A WRIGHT, AND S R BLOOM ...... 89Histological appearances of oesophagus, antrum and duodenum, and their correlation with symptoms in patientswith a duodenal ulcer R J EARLAM, J AMERIGO, T KAKAVOULIS, AND D J POLLOCK................................................ 95Case reports: Herbal tea induced hepatic veno-occlusive disease: quantification of toxic alkaloid exposure in

adultsCRKUMANA,M NG, SIANG J U LIN, WENDY KO, PUI-CHEE WU, AND D TODD ............................................... 101Correspondence. Books received. News.................................................................................... 105Gut referees .................................................................................... 106

No 2, FEBRUARY 1985

Leading article: D-penicillamine for primary biliary cirrhosis o F W JAMES .............. ...................................... 109Liver and biliary: Double blind controlled trial of d-penicillamine in patients with primary biliary cirrhosis iNEUBERGER, E CHRISTENSEN, B PORTMANN, J CABALLERIA, J RODES, L RANEK, N TYGSTRUP AND ROGER WILLIAMS .......... 114Endoscopic sclerotherapy using absolute alcohol S K KARIN, G K SACHDEVA, R NANDA, J C VIJ, AND B S ANAND ......... 120Detection of gall stones after acute pancreatitis A J GOODMAN, J P NEOPTOLEMOS, D L CARR-LOCKE, D B L FINLAY, ANDD P FOSSARD . ..................................................................................................................... 125Liver in obesity A BRAILLON, J P CAPRON, M A HERVE, C DEGOTI, AND C QUENUM................................................ 133Cholestasis in amoebic liver abscess P NIGAM, A K GUPTA, K K KAPOOR, G R SHARAN, B M GOYAL, AND L D JOSHI ......... 140Alimentary tract and pancreas: Prognosis in Crohn's disease - based on results from a regional patient group from

thecountyofCopenhagen v BINDER, C HENDRIKSEN, AND S KREINER ............................................................146Familial occurrence of complement dysfunction in Crohn's disease: correlation with intestinal symptoms and

hypercatabolism of complement J ELMGREEN, H BOTH, AND V BINDER ................. .......................................... 151Long term prognosis in ulcerative colitis - based on results from a regional patient group from the county of

CopenhagenC HENDRIKSEN, S KREINER, AND V BINDER ............... ............................................................... 158Specific food intolerance: its place as a cause of gastrointestinal symptoms D A FARAH, I CALDER, LOUISE BENSON,AND J F MACKENZIE ..................................................................................................................... 164Acute gluten challenge in treated adult coeliac disease: a morphometric and enzymatic study M G BRAMBLE, S

Contents

PageZUCOLOTO, N A WRIGHT, AND C 0 RECORD. .............................................................................................. 169Changing patterns of coeliac disease frequency: an analysis of Coeliac Society memberhsip records M i S

LANGMAN,THMCCONNELL, D J SPIEGELHALTER, AND R B MCCONNELL.............................................................175Diarrhoea and malabsorption in acquired immune deficiency syndrome: a study of four cases with specialemphasis on opportunistic protozoan infestations R MODIGLIANI, C BORIES, Y LE CHARPENTIER, M SALMERON, BMESSING, A GALIAN, J C RAMBAUD, A LAVERGNE, I DESPORTES, AND B COCHAND-PRIOLLET...................................... 179Increased jejunal prostaglandin E2 concentrations in patients with acute cholera P SPEELMAN, G H RABBANI, KBUKHAVE, AND J RASK-MADSEN............................................................................................................ 188Effect of glyceryl trinitrate on the sphincter of Oddi motility and baseline pressure M STARITZ, T PORALLA, K EWE,K-H MEYER ZUM BUSCHENFELDE........................................................................................................... 194Relation between serum group II pepsinogen concentration and the degree of Brunner's gland hyperplasia inpatients with chronic renal failure H PAIMELA, M HARKONEN, S-L KARONEN, L G TALLGREN, S STENMAN, AND JAHONEN............................................. ........................................................................ 198Methods andtechniques: Plastic pH electrodes for the measurement of gastrointestinal pHJ M RAWLINGS AND M LLUCAS ..................................................................................................................... 203Case reports: Haemodialysis in 'hepatorenal syndrome': report on two cases F KELLER, K WAGNER, T LENZ, W

POMMER,G HAHN, M MOLZAHN, AND P-H KRAUSE.............. ........................................................................ 208Acute delta hepatitis without circulating HBsAg K M DE COCK, SUGANTHA GOVINDARAJAN, AND A G REDEKER .......... 212Correspondence. Books. News........................... ......................................................... 215

No 3, MARCH 1985

Leading article: Upper gastrointestinal bleeding: the trials of trials M J S LANGMAN ........ ................................. 217Alimentary tract and pancreas: Randomised double blind trial of somatostatin in the treatment of massive uppergastrointestinal haemorrhage I MAGNUSSON, T IHRE, C JOHANSSON, U SELIGSON, S TORNGREN, AND K UVNAS-MOBERG 221Comparison of weight, depth, and diagnostic adequacy of specimens obtained with 16 different biopsy forcepsdesigned for upper gastrointestinal endoscopy B J Z DANESH, M BURKE, J NEWMAN, A AYLOTT, P WHITFIELD, AND P BCOTTON ......................................... ............................................................................ 227Acid and gastrin response during intragastric titration in normal subjects and duodenal ulcer patients with G-cell

hyperfunction RGCOOPER, G J DOCKRAY, J CALAM, AND R WALKER ................................................................ 232Duodenal mucosa synthesis of prostaglandins in duodenal ulcer disease K HILLIER, C L SMITH, R JEWELL, M J PARTHUR, AND G ROSS ..................................................................................................................... 237Evaluation of pirenzepine on gastric acidity in healthy volunteers using ambulatory 24 hour intragastric

pH-monitoring A ETIENNE, C J FIMMEL, B A BRON, E LOIZEAU, AND A L BLUM.................................................... 241Effects of cisapride, a new gastrointestinal prokinetic substance, on interdigestive and postprandial motoractivity of the distal oesophagus in man A J P M SMOUT, J W BOGAARD, A C GRADE, 0 J TEN THIJE, L M A AKKERMANS,AND P WRITTEBOL ..................................................................................................................... 246Regulation of vitamin D and calcium metabolism after gastrectomy L NILAS, C CHRISTIANSEN, AND J CHRISTIANSEN 252Elastosis in diverticular disease of the sigmoid colon JANET WHITEWAY AND B C MORSON.................................... 258Cell kinetics and in vitro clonogenicity of primary colorectal cancer: clinicopathological relationships and theimplications for chemotherapy G A TROTTER, G R MORGAN, A J COOPER, N KIRKHAM, J M A WHITEHOUSE, AND I TAYLOR 267Crohn's disease in Blackpool - incidence and prevalence 1968-80 F I LEE AND F T COSTELLO ....... ....................... 274Role of the faecal stream in the maintenance of Crohn's colitis P H HARPER, E C G LEE, M G W KETrLEWELL, M KBENNETT, AND D P JEWELL ................................................................................................................. 279Impaired suppressor activity in children affected by coeliac disease c PIGNATA, R TRONCONE, G MONACO, M CIRIACO,E FARRIS, G CARMINATI, AND S AURICCHIO ...................... ......................................................................... 285Liver and biliary: Role of plasmapheresis in primary biliary cirrhosis L B COHEN, E P AMBINDER, A M WOLKE, S PFIELD, AND F SCHAFFNER .................................. ................................................................................. 291Case reports: Kaposi's sarcoma of the bowel - presenting as apparent ulcerative colitis J N WEBER, D J

CARMICHAEL,ABOYLSTON, A MUNRO, W P WHITEAR, AND A J PINCHING ............................................................295Acute fulminating amoebic colitis: survival after total colectomy R R BABB AND M L TROLLOPE ....... ..................... 301Congenital short pancreas: a report of two cases N H GILINSKY, G DEL FAVERO, P B COTTON, AND W R LEES .............. 304Absent ileal uptake of IF-bound vitamin B12 in vivo in the Imerslund-Grasbeck syndrome (familial vitamin B12malabsorption with proteinuria) J F BURMAN, W J JENKINS, J A WALKER-SMITH, A D PHILLIPS, N A SOURIAL, C BWILLIAMS, AND D L MOLLIN ................................................................................................................ 311Cholestatic jaundice in the haemolytic-uraemic syndrome: a case report G JEFFREY, C C KIBBLER, R BAILLOD, KFARRINGTON AND MARSHA Y MORGAN.................................. 315Correspondence. Books. News ...................... ............................................................. 320

Contents

No 4, APRIL 1985Page

Leading article: Spontaneous bacterial peritonitis I R CROSSLEY AND ROGER WILLIAMS....................................... 325Liver and biliary: Ascitic fluid pH in alcoholic cirrhosis: a re-evaluation of its use in the diagnosis of spontaneousbacterial peritonitis J SCEMAMA-CLERGUE, C DOUTRELLOT-PHILIPPON, J-M METREAU, B TEISSEIRE, D CAPRON, AND DDHUMEAUX ................................................................................................................... 332Alimentary tract and pancreas: Oesophageal motor events at the occurrence of acid reflux and duringendogenous acid exposure in healthy subjects and in patients with oesophagitis F BALDI, F FERRARINI, R

BALESTRA,DBORIONI, ANNAMARIA LONGANESI, M MIGLIOLI, AND L BARBARA....... .............................................. 336Relationship between gastric emptying of solids and gall bladder emptying in normal subjects J N BAXTER, J SGRIME, M CRITCHLEY, AND R SHIELDS. .................................................................................................... 342Measurement of gastric emptying in dyspeptic patients: effect of a new gastrokinetic agent (cisapride) R JIAN, F

DUCROT, CPIEDELOUP, J Y MARY, Y NAJEAN, AND J J BERNIER........................................................................ 352Non-steroidal anti-inflammatory drugs and peptic ulcer perforation D STJ COLLIER ANDJ A PAIN ...... .................. 359Uptake and subcellular localisation of bismuth in the gastrointestinal mucosa of rats after short termadministration of colloidal bismuth subcitrate D STIEL, D J MURRAY, AND T J PETERS.......................................... 364Lysophosphatidylcholine increases rat ileal permeability to macromoleculesc TAGESSON, L FRANZEN, G DAHL, ANDB WESTROM................................................ ................................................................. 369In vivo assessment of granulocyte migration to diseased bowel in Crohn's disease H SAVERYMUTrU, A M PETERS, J PLAVENDER, V S CHADWICK, AND H J F HODGSON. ........................................................................................ 378Mechanical properties of the colon: comparison of the features of the African and European colon in vitro D A KWATTERS, A N SMITH, MA EASTWOOD, K C ANDERSON, R A ELTON, AND J W MUGERWA........................................... 384Clinical evaluation of the histochemical diagnosis of Hirschsprung's disease L C BARR, J BOOTH, M I FILIPE, AND0 N LAWSON . ................................................................................................................... 393

Topical administration of 5-aminosalicylic acid enemas in patients with ulcerative colitis. Studies on rectalabsorption and excretion M CAMPIERE, G A LANFRANCHI, S BOSCHI, C BRIGNOLA, G BAZZOCCHI, P GIONCHEITI, M RMINGUZZI, A BELLUZZI, AND G LABO. ...................................................................................................... 400Comparative radiological and morphological study of human pancreas. Pancreatitis like changes in postmortemductograms and their morphological pattern. Possible implication for ERCP P SCHMITZ-MOORMANN, G WHIMMELMANN, J-W BRANDES, U R FOLSCH, H LORENZ-MEYER, H MALCHOW, L N SOEHENDRA, AND M WEINBECK..... ....... 406Clinical trials: Lactitol in the treatment of chronic hepatic encephalopathy: an open comparison with lactulosePHILIPPE L LANTHIER AND MARSHA Y MORGAN........................................................................................... 415B1 selective adrenoreceptor blockade for the long term management of variceal bleeding. A prospectiverandomised trial to compare oral metoprolol with injection sclerotherapy in cirrhosis D WESTABY, W M MELIA,

BRDMACDOUGALL,J E HEGARTY, A E GIBSON, AND ROGER WILLIAMS .............................................................. 421Case reports: Neuroendocrine islet cell tumour producing gastrin and ACTH in a patient with calcifying chronicpancreatitis M C ALLISON, C C RENFREW, W J S WEBB, M E CHAPPELL AND R E POUNDER....... .................................. 426Correspondence. Books. News.......................... .......................................................... 429

No 5, MAY 1985

Leading article: New somatostatin molecule for management of endocrine tumours S BONFILS ....... ................... 433Alimentary tract and pancreas: Treatment of patients with pancreatic endocrine tumours using a new long-actingsomatostatin analogue symptomatic and peptide responses s M WOOD, M E KRAENZLIN, T E ADRIAN, AND S R BLOOM 438Is somatostatin a humoral regulator of the endocrine pancreas and gastric acid secretion in man? F B LOUD, J J

HOLST, E EGENSE, B PETERSEN, AND J CHRISTIANSEN................................................................................... 445Enzyme immunoassay of pancreatic oncofetal antigen (POA) as a marker of pancreatic cancer K NISHIDA, MSUGIURA, T YOSHIKAWA, AND M KONDO. .................................................................................................. 450Monoclonal antibody defines CA 19-9 in pancreatic juices and sera W H SCHMIEGEL, C KREIKER, W EBERL, R ARNDT,M CLASSEN, H GRETEN, K JESSEN, H KALTHOFF, N SOEHENDRA, AND H-G THIELE.................................................. 456Crohn's disease in the elderly P J FABRICIUS, A N GYDE, P SHOULDER, M R B KEIGHLEY, J ALEXANDER-WILLIAMS, ANDR N ALLAN ................................. ................................................................................ 461Faecal sulphatase in health and in inflammatory bowel disease J M RHODES, RUTH GALLIMORE, E ELIAS, AND J FKENNEDY ................................................................................................................... 466Anorectal incontinence and rectal prolapse: differential assessment of the innervation to puborectalis andexternal anal sphincter muscles s J SNOOKS, M M HENRY, AND M SWASH.......................................................... 470Electrohydrothermoprobe - a simple alternative to laser therapy in the management of acute gastrointestinal

haemorrhage C M BATE AND L ABDUL AZIZ ....................... ...................................................................... 477Conservative treatment of gastrointestinal haemorrhage S B ROFE, J M DUGGAN, E R SMITH AND C J THURSBY ...... ..... 481

Contents

PageGastrin sensitivity in duodenal ulcer SHIU-KUM LAM AND JARLEY KOO. ........................................................... 485Gastric acid secretion in patients with typhoid feverF BHALLA,J C VIJ, BS ANAND, A VARGHESE, AND H K CHUTTANI 491Bile acid concentrations in the gastric juice of patients with erosive oesophagitis BJ COLLINS, G CROTHERS, RJMCFARLAND, A'4D A H G LOVE .............................................................................................................. 495Sources of proteins in human bile BARBARA M MULLOCK, LYNNE J SHAW, B FITZHARRIS, JANE PEPPARD,

MJRHAMILTON, M T SIMPSON, T M HUNT, AND R H HINTON....... .................................................................... 500Liver and biliary: Analysis of the antigenic composition of liver specific lipoprotein using murine monoclonalantibodies K H WIEDMANN, L K TREJDOSIEWICZ, A H GOODALL, AND H C THOMAS................................................ 510Hyperenteroglucagonaemia and small intestinal mucosal growth after colonic perfusion of glucose in rats B MMIAZZA, M Y R AL-MUKHTAR, M SALMERON, M A GHATEL, M FELCE-DACHEZ, A FILALI, RVILLET, N A WRIGHT, S R BLOOM,AND J-C RAMBAUD..................................................................................................................... 518Intravascular oesophageal variceal pressure (IOVP) assessed by endoscopic fine needle puncture under basalconditions, Valsalva's manoeuvre and after glyceryltrinitrate application M STARITZ, T PORALLA, AND K-H MEYERZUM BUSCHENFELDE..................................................................................................................... 525Case report: Cronkhite Canada syndrome: a new hypothesis K FREEMAN, P P ANTHONY, D S MILLER, AND A P WARIN 531Correspondence. Books. News................................. ................................................... 537British Society of Gastroenterology.................................................................................... A541

No 6, JUNE 1985

Leading article: Diet and diverticulosis - new leads K W HEATON............. ................................................... 541Alimentary tract and pancreas: Diet and other factors in the aetiology of diverticulosis: an epidemiological studyin Greece 0 MANOUSOS, N E DAY, A TZONOU, C PAPADIMITRIOU, A KAPETANAKIS, A POLYCHRONOPOULOU-TRICHOPOULOU, AND D TRICHOPOLOUS. .................................................................................................. 544Calcitonin gene related peptide inhibits basal, pentagastrin, histamine, and bethanecol stimulated gastric acid

secretionHJLENZ, MTMORTRUD,J E RIVIER, AND M R BROWN...................................................................... 550(2'-5') Oligo adenylate synthetase activity in leucocytes of patients with inflammatory bowel disease R

STALNIKOWICZ, KGODER,F KARMELI, C FIOCCHI, AI$D D RACHMILEWITZ........................................................... 556Acetate absorption and metabolism in the rabbit hindgutJ F MARTY, M YVERNAY, AND G M ABRAVANEL..... ............ 562Enteropathogenic Escherichia coli enteritis: evaluation of the gnotobiotic piglet as a model of human infection sTZIPORI, R M ROBINS-BROWNE, GENA GONIS,JANE HAYES, MAREE WITHERS, AND ELINOR MCCARTNEY ...... ................... 570Intestinal permeability to 51Cr-EDTA in rats with experimentally induced enteropathy I BJARNASON, PSMETHURST, AJ LEVI, AND TJ PETERS. .................................................................................................... 579Long term results of treatment of vascular malformations of the gastrointestinal tract by Neodymium Yag laserphotocoagulation P RUTGEERTS, F VAN GOMPEL, K KEBOES, G VANTRAPPEN, L BROECKAERT, AND G COREMANS..... ........586Effect of omeprazole on the secretion of intrinsic factor, gastric acid and pepsin in man E KITrANG, E AADLAND,AND H SCHJ0MSBY..................................................................................................................... 594Maintenance therapy: a two year comparison between Caved-S and cimetidine treatment in the prevention ofsymptomatic gastric ulcer recurrence A G MORGAN, C PACSOO, AND W A F MCADAM............................................ 599Prevention of duodenal ulcers in the rat using a combination of ranitidine and sucralphate in subtherapeutic

dosesSBANK,HZIMMERMAN, C SMOLOW, AND VICTORIA KRANZ .................................................................... 603Epigastric impedance: a non-invasive method for the assessment of gastric emptying and motilityG R MCCLELLAND AND J A SUITON. ........................................................................................................ 607Pressure, volume and the pancreas C P ARMSTRONG, T V TAYLOR, AND H B TORRANCE.......................................... 615HLA-DR antigens in primary biliary cirrhosis: lack of association MF BASSENDINE, PJ DEWAR, AND 0 F W JAMES .....625Liver and biliary: Renal function impairment induced by change in posture in patients with cirrhosis and ascites MBERNARDI, COSTANZA SANTINI, F TREVISANI, M BARALDINI, A LIGABUE, AND G GASBARRINI..................................... 629Case reports: Ketoconazole-induced fulminant hepatitis E BERCOFF, J BERNUAU, C DEGOTT, B KALIS, A LEMAIRE, HTILLY, B RUEFF, AND J P BENHAMOU....................................................................................................... 636Acute fulminant non-A, non-B hepatitis leading to chronic active hepatitis after treatment with cryoprecipitateCHRISTINE A LEE, P B A KERNOFF, P KARAYIANNIS, AND H C THOMAS................................................................. 639Correspondence. Books. News ........................ ............................................................ 642Pancreatic Society of Great Britain and Ireland.................................................................................... A648

No 7, JULY 1985

Leading article: Intestinal ischaemia I E GILLESPIE................................................................................... 653Alimentary tract and pancreas: Intestinal function and intestinal blood supply: a 20 year surgical study A

Contents

PageMARSTON,JMFCLARKE,J GARCIA GARCIA, AND A L MILLER.......................................................................... 656

Antibodies to gliadin detected by immunofluorescence and a micro-ELISA method: markers of active childhoodand adult coeliac disease U VOLTA, M LENZI, ROSANNA LAZZARI, F CASSANI, ANGELA COLLINA, F B BIANCHI, AND E PISI 667Gut associated lymphoid tissue: a morphological and immunocytochemical study of the human appendix joSPENCER, TERESA FINN, AND P G ISAACSON. ............................................................................................. 672Prostaglandins are not mediators of the intestinal response to cholera toxin G S SMITH, G WARHURST, A TONGE, ANDLATURNBERG .......................................................................................................................... 680Autonomic regulation of postprandial plasma somatostatin, gastrin, and insulin M R LUCEY, J A H WASS, PFAIRCLOUGH, J WEBB, S MEDBAK, AND L H REES. ....................................................................................... 683Altered solid and liquid gastric emptying in patients with duodenal ulcer disease G J MADDERN, M HOROWITZ, DHETZEL AND G G JAMIESON. ................................................................................................................. 689Relative nutritional value of whole protein, hydrolysed protein and free amino acids in man K J MORIARTY, J E

HEGARTY,PDFAIRCLOUGH, M J KELLY, M L CLARK, AND A M DAWSON.............................................................. 694Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath testG BASILISCO, A BOZZANI, G CAMBONI, M RECCHIA, M QUARTRINI, D CONTE, R PENAGINI, AND P A BIANCI.... .................. 700Topical methotrexate alters solute and water transport in the rat jejunum in vivo and rabbit ileum in vitro C RPINKERTON, I W BOOTH, AND P J MILLA. ................................................................................................... 704Rectal mucosal morphological abnormalities in normal subjects in southern India: a tropical colonopathy?MINNIE M MATHAN AND V I MATHAN ....................................................................................................... 710Distal transposition of rat caecum does not render it susceptible to carcinogenesis J B RAINEY, M MAEDA, AND R C NWILLIAMSON ........................................................................................................................... 718Acute pancreatitis: a lethal disease of increasing incidence A P CORNFIELD, MJ COOPER, AND RC N WILLIAMSON .......724Liver and biliary: Medium term complications of endoscopicbiliary sphincterotomy P A WINSTANLEY,W R ELLIS, EHAMILTON, D J LINTOTT, AND A T R AXON. ............................................................................................... 730Gall bladder sludge formation during prolonged fasting after gastrointestinal tract surgery L BOLONDI, S GAIANI, STESTA, AND G LABO.......................................................................................................................... 734Peripheral blood mononuclear cells and regulatory T cells in acute viral hepatitis v BARNABA, E TAMBURRINI, V

LAGHI,RCAUDA,MLEVRERO,G RUOCCO, L ORTONA, AND F BALSANO............................................................... 739Clinical trial: Randomised controlled trial of adenine arabinoside 5'-monophosphate (ARA-AMP) in chronichepatitis B virus infection I V D WELLER, ANNA S F LOK, A MINDEL, P KARAYIANNIS, SARAH GALPIN, J MONJARDINO,

SHEILA SHERLOCK, AND H C THOMAS...................................................................................................... 745Case report: Use of CAT scanning in the diagnosis and management of hepatic artery aneurysm C C KIBBLER, D LCOHEN, J K CRUICKSHANK, S S KUSHWAHA, MARSHA Y MORGAN, AND R D DICK.................................................... 752Correspondence. Books. News............................... ........................................................ 757

No 8, AUGUST 1985

Alimentary tract and pancreas: Faecal mucus degrading glycosidases in ulcerative colitis and Crohn's disease J MRHODES,RUTHGALLIMORE, E ELIAS, R N ALLAN, AND J F KENNEDY ................................................................. 761

Effect of cimetidine on gastric secretion and duodenogastric reflux R J MELVILLE, S I SULEIMAN, P F WHITFIELD, J VPARKIN, T 0 NWABUNIKE, AND M HOBSLEY............................................................................................... 766Effect of cimetidine and omeprazole on aspirin - and taurocholate induced gastric mucosal damage in the rat R J

UTLEY, A S M SALIM, AND DC CARTER ..................................................................................................... 770Gastric acid and pancreatic polypeptide responses to modified sham feeding: indication of an increased basalvagal tone in a subgroup of duodenal ulcer patients ANNA KOHN, B ANNIBALE, G SURIANO, CAROLA SEVERI, SABRINA

SPINELLA, AND G DELLE FAVE.............................................................................................................. 776Origin of chronic right upper quadrant pain J G C KINGHAM AND A M DAWSON .......... ....................................... 783Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the

firstsymptoms J HMCINTOSH, KAREN BYTH, AND D W PIPER ......................................................................... 789Does age influence normal gastro-oesophageal reflux? R A J SPENCE, B J COLLINS, T G PARKS, AND A H G LOVE .........799Influence of morphine on the distal oesophagus and the lower oesophageal sphincter - a manometric study K

DOWLATSHAHI, AEVANDER, B WALTHER, AND D B SKINNER .......................................................................... 802Effect of warfarin on cell kinetics, epithelial morphology and tumour incidence in induced colorectal cancer inthe rat NICOLA GOETING, G A TROTTER, T COOKE, N KIRKHAM AND I TAYLOR........................................................ 807Morphometric study of the small intestinal mucosa in young, adult, and old rats submitted to protein deficiencyand rehabilitation MARIA A M RODRIGUES, J L V DE CAMARGO, K I R COELHO, M R G MONTENEGRO, A Y 0 ANGELELI, AND

R C BURINI . .......................................................................................................................... 816Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis P B MCINTYRE, F A MACRAE, L

BERGHOUSE, J ENGLISH, AND J E LENNARD-JONES ...................................................................................... 822

Contents

PageWhat is the significance of pancreatic ductal mucinous hyperplasia? T G ALLEN-MERSH..................................... 825Interpretation of the breath hydrogen profile obtained after ingesting a solid meal containing unabsorbablecarbohydrate N W READ, M N AL-JANABI, T E BATES, A M HOLGATE, P A CANN, R I KINSMAN, A MCFARLANE, ANDCHRISTINE BROWN...................................................................................................................... 834Liver and biliary: Endoscopic variceal pressure measurements: response to isosorbide dinitrate J DAWSON, PPERTSCH, F MOSIMANN, R WEST, AND E ELIAS.............. ............................................................................. 843Progress report: Natural history of the HBsAg carrier M G ANDERSON AND I M MURRAY-LYON.............................. 848Case report: Development of impaired splenic function in intestinal lymphangiectasia P N FOSTER, AW BULLEN,

DAFROBERTSON, D M CHALMERS, AND M S LOSOWSKY. ............................................................................... 861Correspondence. Books. News............................ ........................................................ 865

No 9, SEPTEMBER 1985

Leadingarticle: The gay bowel I V D WELLER.............. ........................................................................... 869Alimentary tract and pancreas: Enzyme transfer from pancreas to plasma during acute pancreatitis. Thecontribution of ascitic fluid and lymphatic drainage of the pancreas A D MAYER, M AIREY, JAHAN HODGSON, AND M JMCMAHON ...................................................................................................................... 876Diet and drinking habits in relation to the development of alcoholic pancreatitis i S WILSON, L BERNSTEIN, CMCDONALD, A TAIT, D MCNEIL, AND R C PIROLA............... .......................................................................... 882Impaired lipid clearance in patients with previous acute pancreatitis S GUZMAN, F NERVI, O LLANOS, P LE6N, AND VVALDIVIESO ...................................................................................................................... 888Effect of cimetidine on enzyme inactivation, bile acid precipitation, and lipid solubilisation in pancreaticsteatorrhoea due to cystic fibrosis P L ZENTLER-MUNRO, D R FINE, J C BATrEN, AND T C NORTHFIELD ...... ................. 892Intravenous omeprazole rapidly raises intragastric pH R P WALT, J R REYNOLDS, M J S LANGMAN, H L SMART, G

KITCHINGMAN, K W SOMERVILLE, AND C J HAWKEY............. ........................................................................ 902Influence of protein composition and hydrolysis method of intestinal absorption of protein in man P P KEOHANE,

GKGRIMBLE,BARBARA BROWN, R C SPILLER, AND D B A SILK......................................................................... 907Gastric acid secretion and gastrin production in the short bowel syndrome N S WILLIAMS, P EVANS, AND R F G J KING 914Adrenergic effects on secretion of epidermal growth factor from Brunner's glands P SKOV OLSEN, S S POULSEN,AND P KIRKEGAARD ..................................................................................................................... 920Plasma cell infiltration of the small bowel: lack of evidence for a non-secretory form of alpha heavy chain diseaseN H GILINSKY, A S MEE, D W BEATTY, B H NOVIS, G YOUNG,-S PRICE, L RPURVES, AND IN MARKS ...... ......................... 928Pathology of the alimentary tract in Salmonella typhimturium food poisoning J F BOYD..................................... 935Campylobacter colitis: histological immuno-histochemical and ultrastructural findings i P VAN SPREEUWEL, G CDUURSMA, C J L M MEIJER, R BAX, P C M ROSEKRANS, AND J LINDEMAN.............................................................. 945Ulcerative colitis and HLA phenotype M COTTONE, M BUNCE, C J TAYLOR, A TING, AND D P JEWELL........................ 9521Indium autologous granulocytes in the detection of inflammatory bowel disease S H SAVERYMUTTU, A M PETERS,

MECROFTON,HREES, J PLAVENDER, H J F HODGSON, AND V S CHADWICK ......................................................... 955Liver and biliary: Computer-aided selection of diagnostic tests in jaundiced patients M-F SAINT-MARC GIRARDIN,M LE MINOR, A ALPEROVITCH, F ROUDOT-THORAVAL, J-M METREAU, AND D DHUMEAUX .......................................... 961Progress report: Some aspects of the epidemiology of ulcerative colitis J F MAYBERRY ......... ............................. 968Clinical trial: Effect of (+)-cyanidanol-3 on chronic active hepatitis: a double blind controlled trial S BAR-MEIR, ZHALPERN, M GUTMAN, Z SHPIRER, MIMI BARATZ, AND D BASS......................................................................... 975Correspondence. Books. News ....................... ............................................................. 980

No 10, OCTOBER 1985

Leading article: Diet in the management of Crohn's disease A J LEVI ............... ............................................ 985Alimentary tract and pancreas: Low residue or normal diet in Crohn's disease: a prospective controlled study in

ItalianpatientsSLEVENSTEIN, C PRANTERA, C LUZI, AND A D'UBALDI .............................................................989Controlled trial comparing prednisolone with an elemental diet plus non-absorbable antibiotics in active Crohn's 994disease S SAVERYMUTTU, H J F HODGSON, AND V S CHADWICK......................................................................

Crypt cell production rate in ulcerative proctocolitis: differential increments in remission and relapse A ALLAN, J BBRISTOL, AND R C N WILLIAMSON. .......................................................................................................... 999Genetic influences on splenic function in coeliac disease J G O'GRADY, F M STEVENS, AND C F MCCARTHY ...... ........... 1004Studies on the mechanism of action of dioctyl sodium sulphosuccinate in the human jejunum K J MORIARTY, M JKELLY, R BEETHAM, AND M L CLARK....................................................................................................... 1008

Contents

PageEffect of L-dopa with and without inhibition of extra cerebral dopa decarboxylase on gastric acid secretion andgastrin release in man R CALDARA, C BARBIERI, V PIEPOLI, M BORZIO, AND E MASCI.............................................. 1014Basal, sham feed and pentagastrin stimulated gastric acid, pepsin and electrolytes after omeprazole 20 mg and40mg daily J N THOMPSON, J A BARR, N COLLIER, J SPENCER, A BUSH, L COPE, R J N GRIBBLE, AND J H BARON..... ........... 1018Gastric mucosal damage in sepsis - effects of pretreatment with a synthetic prostaglandin El analogue sARVIDSSON, K FALT, AND UHAGLUND. .................................................................................................... 1025Duodenal bulb plasma cells in duodenitis and duodenal ulceration B B sCoTr, ANNE GOODALL, P STEPHENSON, ANDD JENKINS..................................................... ................................................................ 1032Duodenal ulcer healing by separate reduction of postprandial and nocturnal acid secretions have differentpathophysiology SHIU-KUM LAM, CHING-LUNG LAI, MATTHEW NG,KAI-HING FOK, AND WAI-MO HUI ..... .................... 1038Polyps and diverticula of the large intestine: a necropsy survey in Hong Kong P E COODE, KW CHAN, AND Y T CHAN 1045Balloon expulsion from the rectum in constipation of different types P R H BARNES AND J E LENNARD-JONES ........... 1049Elution of cytomegalovirus antibodies from adenocarcinoma of the colon ANN GRAIL AND MARY NORMAL..... ........ 1053Positive correlation between symptoms and circulating motilin, pancreatic polypeptide and gastrin concentra-tions in functional bowel disorders D M PRESTON, T E ADRIAN, N D CHRISTOFIDES, J E LENNARD-JONES, AND S R BLOOM 1059Liver and biliary: Acetaldehyde alone may initiate hepatocellular damage in acute alcoholic liver disease R EBARRY AND J D MCGIVEN.................................................................................................................... 1065Morbidity and mortality after peritoneovenous shunt surgery for refractory ascites D RUBINSTEIN, I MCINNES, ANDF DUDLEY.................................................. ................................................................... 1070Platelet associated immunoglobulins in primary biliary cirrhosis: a cause of thrombocytopenia? M F BASSENDINE,J D COLLINS, J STEPHENSON, P SAUNDERS, AND 0 F W JAMES.......................................................................... 1074Clinical trial: Incompletely and completely healed duodenal ulcers' outcome in maintenance treatment: a doubleblind controlled study P PAOLUZI, G RICOTTA, F RIPOLI, F PROIETTI, E ZACCARDELLI, R CARRATU, AND A TORSOLI.......... 1080Case report: Crohn's disease in two married couples J M RHODES, T MARSHALL, J D HAMER, AND R N ALLAN..... ........ 1086Apoint of view: What has technology done to gastroenterology? C C BOOTH........... ....................................... 1088

Correspondence. Books. News .......................... .......................................................... 1095New President of the BSG.................................................................................... 1099British Society of Gastroenterology.................................................................................... A1100

No 11, NOVEMBER 1985

Leading article: Histamine and the pathogenesis of duodenal ulcer disease M E PARSONS ........ .......................... 1159Alimentary tract and pancreas: Sample taking problems in measuring actual histamine levels of humangastroduodenal mucosa: specific and general relevance in clinical trials on peptic ulcer pathogenesis and selectiveproximal vagotomy K PTHON, W LORENZ, ch OHMANN, D WEBER, H ROHDE, AND H D ROHER................................. 1165Serum pepsinogens I and II and gastric mucosal histology after partial gastrectomy P SIPPONEN, I M SAMLOFF, MSAUKKONEN, AND K VARIS ................................................................................................................... 1179Campylobacter pyloridis in peptic ulcer disease: microbiology, pathology, and scanning electron microscopy A BPRICE, J LEVI, JEAN M DOLBY, P L DUNSCOMBE, A SMITH, J CLARK, AND MARY L STEPHENSON ....... ............................ 1183Somatostatin inhibits gastric acid secretion after gastric mucosal prostaglandin synthesis inhibition byindomethacin in man M H MOGARD, V MAXWELL, T KOVACS, G VAN DEVENTER, J D ELASHOFF, T YAMADA, G LKAUFFMAN JR, AND J H WALSH ............................................................................................................. 1189Cigarette smoking reduces human gastric luminal prostaglandin E2 D R MCCREADY, L CLARK, AND M M COHEN ........ 1192Vitamin D status in Crohn's disease: association with nutrition and disease activity A D HARRIES, R BROWN, R V

HEATLEY,L AWILLIAMS, S WOODHEAD, AND J RHODES ............... ................................................................. 1197Does the reticulin binding property of cereal proteins demonstrable in vitro have pathogenetic significance forcoeliac disease? D J UNSWORT HAND E J HOLBOROW................................................................................... 1204DR and non-DR Ia allotypes are associated with susceptibility to coeliac disease G R CORAZZA, P TABACCHI, MFRISONI, C PRATI, AND G GASBARRINI................................. 1210Intestinal permeability in patients with coeliac disease and dermatitis herpetiformis I BJARNASON, M N MARSH, APRICE, A J LEVI, AND T J PETERS . ............................................................................................................ 1214Liver and biliary: Granulomatous involvement of the liver in patients with AIDS M S ORENSTEIN, A TAVITIAN, B

YONK,HPDINCSOY, J ZEREGA, S K IYER, AND E W STRAUS ............................................................................ 1220Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy? T T MCCORMACK, J SIMS, I

EYRE-BROOK,HKENNEDY, J GOEPEL, A G JOHNSON, AND D R TRIGER ................................................................ 1226Antibody mediated hepatocyte injury in methyl dopa induced hepatotoxicity J NEUBERGER, G KENNA, K NOURIARIA, AND R WILLIAMS ..................................................................................................................... 1233Biliary excretion of radioactivity after intravenous administration of 3H-1,25-dihydroxyvitamin D3 in man J E

Contents

PageLEDGER, G J WATSON, C C AINLEY, AND J E COMPSTON .1240Conjugated bile acids in serum and secretions in response to cholecystokinin/secretin stimulation in children withcystic fibrosis T A ROBB, G P DAVIDSON, AND C KIRUBAKARAN .1246Comparison of the oral (PABA) pancreatic function test, the secretin-pancreozymin test and endoscopicretrograde pancreatography in chronic alcohol induced pancreatitis A S MEE, A H GIRDWOOD, E WALKER, N H 1257GILINSKY, R E KOTTLER, AND I N MARKS .

Case reports: Development of cimetidine resistance in the Zollinger-Ellison syndrome B NYBOE ANDERSEN, N-ELARSEN, S J RUNE, AND H WORNING .1263Chylous ascites, intestinal lymphangiectasia and the 'yellow-nail' syndromeP M DUHRA, E M M QUIGLEY, AND M N

MARSH.1266Correspondence. Books. News .1270

No 12, DECEMBER 199'5

Leading articles: Abdominal tuberculosis P F SCHOFIELD........................................................................... 1275Inhibition of acid and gastric carcinoids J B ELDER................................................................................... 1279Alimentary tract and pancreas: Association of long lasting unsurmountable histamine H2 blockade and gastriccarcinoid tumours in the rat D POYNTER, C R PICK, R A HARCOURT, SAM SELWAY, G AINGE, I W HARMAN, N W SPURLING,P A FLUCK, AND J L COOK.................................................................................................................... 1284Abdominal tuberculosis in urban Britain - a common disease K R PALMER, D H PATIL, G S BASRAN,J F RIORDAN, ANDDBASILK................................................................... ................................................... 1296Circulating human leucocyte elastase in patients with inflammatory bowel disease EO ADEYEMI, S NEUMANN, V SCHADWICK, HJ F HODGSON, AND M B PEPYS.............. .............................................................................. 1306

Histochemical demonstration of desialation and desulphation of normal and inflammatory bowel disease rectalmucus by faecal extractsJ M RHODES, R R BLACK, R GALLIMORE, AND A SAVAGE........ ......................................... 1312Incomplete sulphomucin-secreting intestinal metaplasia for gastric cancer. Preliminary data from a prospectivestudy from three centres M I FILIPE, F POTET, W V BOGOMOLETZ, P A DAWSON, B FABIANI, P CHAUVEINC, A FENZY, BGAZZARD, D GOLDFAIN, AND R ZEEGEN. ................................................................................................. 1319Cigarette smoking, gastric acid secretion and serum pepsinogen I concentrations in duodenal ulcer patients FPARENTE, M LAZZARONI, ORNELLA SANGALETTI,STEFANIABARONI, AND BIANCHI PORRO ....................................... 1327Cigarette smoking and duodenal ulcer D H HULL AND PJ BEALE. ................................................................. 1333

Endoscopic laser treatment of vascular anomalies of the upper gastrointestinal tract S G BOWN, C P SWAIN, D WSTOREY,CCOLLINS, KMATTHEWSON, P R SALMON, AND C G CLARK.................................................................. 1338

Extra intestinal influences on exhaled breath hydrogen measurements during the investigation of gastrointestinaldisease D G THOMPSON, P BINFIELD, A DE BELDER, JO BRIEN, S WARREN, AND M WILSON....................................... 1349Is raised plasma peptide YY after intestinal resection in the rat responsible for the trophic response? A P SAVAGE,G E GORNACZ, T E ADRIAN, M A CHATEI, R A GOODLAD, N A WRIGHT, AND S R BLOOM ............................................. 1353Liver and biliary: Clinical course of cirrhosis in young adults and therapeutic potential of liver transplantation i J

KEATING,RDJOHNSON,P J JOHNSON, AND ROGER WILLIAMS ........................................................................ 1359Inhibitors of collagenolytic enzymes in the serum of patients with chronic liver disorders E J KUCHARZ ..... .......... 1364Abnormal responses to morphine-neostigmine in patients with undefined biliary type pain I C ROBERTS-THOMPSONAND J TOOULI . ...................................................................................................................... 1367Percutaneous transhepatic assistance for duodenoscopic sphincterotomy P i SHORVON, P B COTTON, R R MASON, J HSIEGEL, AND A R W HATFIELD. ............................................................................................................. 1373Comparison between ranitidine and ranitidine plus Caved-S in the treatment of gastric ulceration A G MORGAN, CPACSOO, AND W A F MCADAM ............................................................................................................... 1377Clinical trial: Double blind controlled trial of oral vancomycin as adjunctive treatment in acute exacerbations ofidiopathic colitis R J DICKINSON, H J O'CONNOR, I PINDER, I HAMILTON, D JOHNSTON, AND A T R AXON ....... ................ 1380Case report: Enhancement of renal function with ornipressin in a patient with decompensated cirrhosis K LENZ, WDRUML, G KLEINBERGER, H HORTNAGL, A LAGGNER, B SCHNEEWEIB, AND E DEUTSCH............................................ 1385Correspondence. Books. News ..................... ............................................................... 1387General index to volume 26 .................................................................................... 1391Index to abstracts .................................................................................... 1412