NIATx

NIDAs Clinical Trials Network:Science, Practice & RealityHarold I Perl, PhDCenter for the Clinical Trials NetworkNational Institute on Drug AbuseNIATx Summit and SAAS National ConferenceBoston, MAJuly 13, 2011

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Pick Your Favorite Metaphor

2IOM Report Decries the GapNIDA responds to IOM reportNational Drug Abuse Treatment Clinical Trials Network (CTN) 1999Blending Initiative 2001Based on Bi-DirectionalityClinicians & Researchers collaborating

3CTN MissionStudy behavioral and pharmacological treatments that have high potential for success in community treatment settingsGet research findings into the hands of clinicians who can make the best use of them as fast as possible

4Regional Research and Training Center (RRTC)State with Community Treatment Program (CTP)CTN Across the Nation 5NIDA/SAMHSA Blending InitiativeBlending ConferencesClinical and research experts present latest scientific findings to front-line clinicians and managers Single State Agency DirectorsFacilitate broader adoption of research-supported txBlending Teams & Blending ProductsOperationalize implementation of research findings in the field

6Buprenorphine Treatment: Training for Multidisciplinary Addiction ProfessionalsShort-Term Opioid Withdrawal Using BuprenorphineBuprenorphine Treatment for Young AdultsTreatment Planning MATRS: Utilizing the ASI to Make Required Data Collection UsefulMotivational Interviewing Assessment: Supervisory Tools for Enhancing Proficiency (MIA-STEP)Promoting Awareness of Motivational Incentives (PAMI)Suite of Blending Products

7Selecting Blending ProductsSpecific intervention models drawn from the findings of CTN and other researchDecisions based on key principles of Treatment Research and Implementation ScienceRelevance to intended usersDemonstrated efficacy and effectivenessPotential reach, feasibility and sustainability across array of ecological and organizational settingsFaithful adoption can be enhanced by comprehensive training and ongoing clinical supervision

8Buprenorphine Treatment SuiteTraining for Multidisciplinary Addiction ProfessionalsBroad overview of Buprenorphine use and effectsRole of non-prescribers in patient care6-hour classroom training program and videoSelf-paced CD-ROM awareness courseShort-Term Opioid Withdrawal Using BuprenorphineTeaches the 13-day Buprenorphine taper intervention4-hour classroom training programBuprenorphine Treatment for Young AdultsEffectiveness of longer term treatment for young adults3-hour classroom training and PowerPoint presentation

9Motivational Interviewing Assessment: Supervisory Tools for Enhancing Proficiency (MIA:STEP)Teaching tools for assessing and enhancing counselors MI SkillsSupervisor training curriculum for 6-10 hour workshopAudiotaped treatment sessions and supervisory tape rating guideTools for clinical supervisors to fortify ability to deliver effective supervision to front-line counselors

1010Promoting Awareness of Motivational Incentives (PAMI)Motivational Incentives Awareness VideoPowerPoint presentations for clinicians and policy makersToolkit (activities, sample materials, etc.)Resources (bibliography, articles, FAQ, etc.)Explains research findings that show low-cost incentives can increase drug abstinence and enhance patient retention in treatment speaks to the clinics Bottom Line

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motivationalincentives.org13

motivationalincentives.org

motivationalincentives.org

Motivational Incentives: Positive Reinforcements to Enhance Successful Treatment Outcomes (MI PRESTO)6-Module, On-Demand, Self-Paced CourseNuts and Bolts of how to establish a Motivational Incentive Program

Motivational Incentives Implementation Software (MIIS)Program to utilize and apply incentives in clinic settingMaintain information on patient outcomes, attendance, etc.

16New Blending ProductsCurrently under development

Prescription Opioid Addiction Treatment Study (POATS)

HIV Rapid Testing and Counseling

17Find a Trained Trainer

18Find a Trained Trainer

19Find a Trained Trainer

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Find a Training Event21Find a Training Event

22CTN Impact on Adopting EBPsAdoption of CTN-tested protocols in CTPs 141.9% : Buprenorphine treatment61.4% : Motivational IncentivesAdoption of EBPs tested outside CTN 2CTN CTPs 3 times more likely to adopt acamprosate or naltrexone for AUDs than non-CTN programs CTN CTP staff who participate in research are more likely to use EBPs in clinical practice 31Roman, Abraham, Rothrauff & Knudsen (2010)2Abraham, Knudsen, Rothrauff & Roman, P. M. (2011)3Pinto , Yu, Spector, Gorroochurn & McCarty (2010)1Roman, Abraham, Rothrauff, & Knudsen (2010) A longitudinal study of organizational formation, innovation adoption, anddissemination activities within the National Drug Abuse Treatment Clinical Trials Network Journal of Substance Abuse Treatment 38 (Suppl 1) S44S52

2Abraham, A. J., Knudsen, H. K., Rothrauff, T. C., & Roman, P. M. (2011). The adoption and implementation of alcohol pharmacotherapiesin the Clinical Trials Network. Journal of Substance Abuse Treatment

3Pinto , Yu, Spector, Gorroochurn & McCarty (2010) Substance abuse treatment providers' involvement in research is associatedwith willingness to use findings in practice Journal of Substance Abuse Treatment 39 18819423

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ctndatashare.org

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A Closing ThoughtThe future is already here it's just not evenly distributed.William Gibson (science fiction writer) as quoted in The Economist, December 4, 200329Harold I Perl, PhDSenior Lead for Behavioral Research, Dissemination and TrainingCenter for the Clinical Trials NetworkNational Institute on Drug Abuse301/443-9982hperl@nida.nih.gov

nida.nih.gov/CTN ctndisseminationlibrary.org nida.nih.gov/blending motivationalincentives.orgattcnetwork.org

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