harvesting energy
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Harvesting energy. Genes and Development Biology 122. Substrate level phosphorylation. Glycolysis. - PowerPoint PPT PresentationTRANSCRIPT
Harvesting energy
Harvesting energyGenes and DevelopmentBiology 122Substrate level phosphorylation
GlycolysisThe overall energy balance for glycolysis is as follows:
Priming -2 ATP [use to add phosphates]Harvest +4 ATP [get from phosphates] +2 NADH__________________________________Net +2 ATP +2 NADHOxidation of pyruvateAcetyl-CoA has a central role in metabolism
Not only are sugars broken down to acetyl-CoA, but fats are also broken down to it. In addition, some amino acids in proteins also get broken down into acetyl-CoA
Acetyl-CoA is also used to make fats and some amino acidsThe Citric acid cycleEnergy summary: The complete oxidation of each acetyl-CoA yields
one GTP (equivalent to one ATP)3 NADHsone FADH2 two CO2 molecules are released
ATP synthase tutorial (Marcey site)
ATP synthase animation
Without oxygenNAD+O2
NADHETC in mitochondria
Acetyl-CoA
EthanolNAD+
CO2NAD+
H2O
Lactate
Pyruvate
Acetaldehyde
NADH
NADH
With oxygenKrebsCycle