high free antioxidant

7/30/2019 High Free Antioxidant

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High antioxidant juice

with new concept


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Why human get sick?

b. Because of too much radicalin the body

- not many people know toremove radicals

- do not know right techniqueto take high antioxidant foods


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Do we take enough antioxidants??

Red palm oil ??

Take enough fruit ??
http://www.google.com.my/imgres?imgurl=http://www.thegoodoilcompany.com/images/3bottles.jpg&imgrefurl=http://www.thegoodoilcompany.com/production.html&usg=__skNSucCPcYYHQonDZj6_3sBZ-S4=&h=407&w=300&sz=25&hl=en&start=11&um=1&itbs=1&tbnid=couO_eZppha9CM:&tbnh=125&tbnw=92&prev=/images%3Fq%3Dred%2Bpalm%2Boil%26um%3D1%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26tbs%3Disch:1http://www.google.com.my/imgres?imgurl=http://ictllp.wikispaces.com/file/view/raspberry.jpg/109746157/raspberry.jpg&imgrefurl=http://ictllp.wikispaces.com/food&usg=__SyS836eksFzGcMe0jktQ1F0pkFg=&h=742&w=721&sz=455&hl=en&start=4&um=1&itbs=1&tbnid=mWrsJLTKPXT98M:&tbnh=141&tbnw=137&prev=/images%3Fq%3Draspberry%26um%3D1%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26tbs%3Disch:1http://www.google.com.my/imgres?imgurl=http://www.uasd.edu/pomegranatesymposium/pomegranate.jpg&imgrefurl=http://www.uasd.edu/pomegranatesymposium/&usg=__fDRsJsMuTRkuqzTxbTNnMHhMw5M=&h=400&w=300&sz=78&hl=en&start=1&um=1&itbs=1&tbnid=zmvuVsMjpr9EoM:&tbnh=124&tbnw=93&prev=/images%3Fq%3Dpomegranate%26um%3D1%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26tbs%3Disch:1


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Fresh or over-cookedvegetables

Brown or polished rice

Green tea or teh tarik
http://images.google.co.uk/imgres?imgurl=http://www.apartmenttherapy.com/uimages/kitchen/2008_08_19-Tea.jpg&imgrefurl=http://www.apartmenttherapy.com/ny/slinks/from-the-kitchn-does-milk-negate-teas-health-benefits-060289&usg=__lk47U2hqUxJiVY4eJvGhOGx2kNY=&h=449&w=400&sz=57&hl=en&start=18&um=1&itbs=1&tbnid=NaeMjkjHTH-8kM:&tbnh=127&tbnw=113&prev=/images%3Fq%3Dtea%2Bmilk%26um%3D1%26hl%3Den%26sa%3DN%26rlz%3D1T4ADSA_enMY340MY341%26tbs%3Disch:1http://images.google.co.uk/imgres?imgurl=http://www.greenopia.com/image/news/green-tea.jpg&imgrefurl=http://www.greenopia.com/USA/news/15649/11-2-2009/Top%2520Natural%2520Ways%2520to%2520Fight%2520Allergies%2520and%2520Asthma%2520for%2520Fall&usg=__e8YcyXw0s48_5mUWIkyfx5xP5v0=&h=305&w=300&sz=26&hl=en&start=1&um=1&itbs=1&tbnid=4gEng0J51ypR0M:&tbnh=116&tbnw=114&prev=/images%3Fq%3Dgreen%2Btea%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26sa%3DN%26um%3D1http://images.google.co.uk/imgres?imgurl=http://www.ogiimpex.com/images/content_pic/brown_rice.jpg&imgrefurl=http://www.ogiimpex.com/rice.php%3Flang%3Den&usg=__-nNSgdGgyWAh4s-uQDlHSds2cXY=&h=302&w=318&sz=34&hl=en&start=2&um=1&itbs=1&tbnid=LADceGC6ftHvEM:&tbnh=112&tbnw=118&prev=/images%3Fq%3Dbrown%2Brice%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26um%3D1


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Pucuk paku merah

Pucuk kaduk

Pucuk gajus

Antioxidant in ulam


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Do we use naturalor artificialcolours?
http://en.wikipedia.org/wiki/File:Anthocyanidine.svghttp://www.google.com.my/imgres?imgurl=http://174.123.135.195/uploads05/3/0/Untitled-219096347.jpg&imgrefurl=http://agriculture.indiabizclub.com/products/turmeric&usg=__72m5ln5t6OKZfyHt-xfs8zvqeNE=&h=200&w=300&sz=16&hl=en&start=5&um=1&itbs=1&tbnid=EGe86eRDj6PGbM:&tbnh=77&tbnw=116&prev=/images%3Fq%3Dyellow%2Bcurcumin%26um%3D1%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26tbs%3Disch:1http://www.google.com.my/imgres?imgurl=http://www.olelantana.com/images/products/clitoria_ternatea.jpg&imgrefurl=http://www.olelantana.com/index.php%3Fmain_page%3Dproduct_info%26cPath%3D37_275%26products_id%3D661&usg=__HQn1R7KGRu5K-3klO-eJUaDXS_k=&h=300&w=300&sz=13&hl=en&start=77&um=1&itbs=1&tbnid=iDRqPlYc91NCRM:&tbnh=116&tbnw=116&prev=/images%3Fq%3Dclitoria%2Bternatea%26start%3D72%26um%3D1%26hl%3Den%26sa%3DN%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26ndsp%3D18%26tbs%3Disch:1http://www.google.com.my/imgres?imgurl=http://www.colourlovers.com/uploads/2008/02/cereal_colors.jpg&imgrefurl=http://lsmithrd.wordpress.com/2009/09/01/how-to-avoid-food-dye/&usg=__t47sAVnoWOhqIo8S-pshyvABPho=&h=292&w=490&sz=45&hl=en&start=82&um=1&itbs=1&tbnid=9rKCyCD2WuQPaM:&tbnh=77&tbnw=130&prev=/images%3Fq%3Dcolors%2Bfood%26start%3D72%26um%3D1%26hl%3Den%26sa%3DN%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26ndsp%3D18%26tbs%3Disch:1


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Antioxidants - compounds that inhibit or delay, but do not completely

prevent oxidation of;

fats

proteins

carbohydrates

DNA

Natural antioxidants;

Vitamin E Vitamin C Carotenoids Coenzyme Q10

Phenolic acids Hydroxycinnamates and stilbenes

Flavonoids Quinones

Essential oils

Antioxidant enzyme

(Superoxide dismutase,catalase and glutathione

peroxidase

Synthetic antioxidants

Butylated hydroxyanisole (BHA)

Butylated hydroxytoluene (BHT).

Antioxidants and health


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ROS and RNS Free radicals

- generated by normal cellularmetabolism- exogenous agents.

ROS can cause damage to cellularmacromolecules

- leading to a process called

oxidative stress

Oxidative stress - implicated in thedevelopment of many diseases

- cancer- cardiac disease

- premature aging

Why phenolics?? Phenolics have received much attention as theysuggested to protect against a variety of disorders,particularly cancer and cardiovascular diseases

Antioxidant - stronger than Vitamin C and E


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O

O

O

O

OO

O

O

O

OH

O

Flavone

Flavonol

Anthocyanin

Flavanone

Flavan-3-ol

Isoflavone

3

45

6

78

1

2

3'

4'

5'

6'

1'

2'

A C

B

O

OH

9

10
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How to identify phenolic compounds??


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HPLC-MS-MS - powerful technique to characteriseand identify phenolics;

- structural information of;

a. aglyconb. type of carbohydratec. interglycosidic linkage

- rapid and accurate e.g. 3 days compareto 3 weeks by NMR

HPLC with tandem mass spectrometry

O

O

O

O aglyconeOH

CH2OH

OHOHOH

HO OH

0,2X1

Y1

Z1

0,2A1 B1

0,2A2

B2

Y0 Z0


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Gas Chromatography Mass Spectrometry (GCMS)

GC-MS - powerful technique to characteriseand identify simple phenolics;

- phenolic acids- derivatise using BSTFA

or MSTFA


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How phenolics can be metabolised

in humans ??


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Stomach

Small intestine

Colon

Phenolic antioxidants

Contains ~1012 microorganism - able to produceenzymes involved in hydrolysis, dehydroxylation,demethylation, ring cleavage, decarboxylationand deconjugation
http://images.google.com.my/imgres?imgurl=http://www.kadagan.bz.tc/images/citrus.jpg&imgrefurl=http://www.kadagan.bz.tc/custom2.html&usg=__JMvUBtXtPPqPlPdqC6iP30sGEa4=&h=216&w=319&sz=33&hl=en&start=226&tbnid=zCsdteAtAyEzkM:&tbnh=80&tbnw=118&prev=/images%3Fq%3Dcitrus%2Bfruit%26start%3D220%26gbv%3D2%26ndsp%3D20%26hl%3Den%26sa%3DNhttp://www.mdhb.com/images/raspberry1.jpg


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Herbal Supplements may sometimes besuccessful in emptying the bowel, but they dont really clean out the bowel orremove the toxic waste. They also dont promote good bacteria. In turn, your

colon health remains unaffected. Essentially herbal supplements will causecontraction which can help to excrete stuff that would have come out anyway.

However, they do not offer a long term solution.Laxativesshould only be used as a temporary solution for constipation. Ongoing use can

cause colitis, dehydration and other awful disorders and diseases of the colon.Laxatives also dont help the compaction issue either, which is the most difficult to

treat. Colon Cleanse is helpful if you want toexperience the benefits of a proper colon cleanse or have mild or chronic

constipation. It is a full intestinal colon cleanse solution that took a team ofscientists two years to develop. The key ingredient is Psyllimax, a derivative ofpsyllium a natural fiber. Psyllimax combined with other special, all natural

ingredients, actually soaks up toxins, and scrubs out those deep crevices where badbacteria and parasites can hide. It removes all impacted feces and completely

detoxes your intestines allowing your body to get all the nutrients it needs.

High fibreYoghurt

How to maintain colons health?


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Potential source of antioxidants

Green Tea
http://www.google.com.my/imgres?imgurl=http://www.teacuppa.com/img/products/Green-Tea-Powder.jpg&imgrefurl=http://www.teacuppa.com/Green-Tea-Powder.asp&usg=__Od4oJILss8yTnk4Spe2wnaD31Dw=&h=280&w=280&sz=20&hl=en&start=173&um=1&itbs=1&tbnid=6hN4f3q8-60SfM:&tbnh=114&tbnw=114&prev=/images%3Fq%3Dgreen%2Btea%26start%3D162%26um%3D1%26hl%3Den%26sa%3DN%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26ndsp%3D18%26tbs%3Disch:1http://www.google.com.my/imgres?imgurl=http://www.istockphoto.com/file_thumbview_approve/3841859/2/istockphoto_3841859-white-tea-green-tea-plant.jpg&imgrefurl=http://www.istockphoto.com/stock-photo-3841859-white-tea-green-tea-plant.php&usg=__ofOlddRf_j7PE8PKY3QsWISyhNU=&h=328&w=380&sz=42&hl=en&start=164&um=1&itbs=1&tbnid=5DrDkWGXUB8XIM:&tbnh=106&tbnw=123&prev=/images%3Fq%3Dgreen%2Btea%26start%3D162%26um%3D1%26hl%3Den%26sa%3DN%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26ndsp%3D18%26tbs%3Disch:1


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potent antioxidant greater than vitamin C and E contains gallic acid derivatives, flavan-3-ols, flavonol, teaflavin and

purine alkaloid. ()-Epigallocatechin gallate - Trolox Equivalent Antoxidant Capacity

(TEAC) value of 3.0.

Green tea

OH

HO O

OH

OH

OH

OHOH

O

O

epigallocatechin gallate

OH

OHOH

HO O

OHOH

epicatechin

OHOH

HO O

OHOH

epigallocatechin

OHO

OH

HO O

OH

OH

epicatechin gallate

OH

OHOH

O


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a. Contains high amount of chlorogenic acid and other caffeloyl

quinic acid derivativesb. Comprise a number of sub-groups;

The most widespreadi. caffeloylquinic acid

ii. feruloylquinic acidiii.p-cumaroylquinic acid

d. Major component in coffee is 5-O-caffeloylquinic acide. 5-O-caffeloylquinic acid showed the highest TEAC value

by 1.4.

5-O-caffeloylquinic acid

Coffee

OH

OH

O

O

OH

HOOCOH

OH

OH

OH

O

O

OH

HOOCOH

OH


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OHOH

OO

OH

OH

HOOCOH

OHOH

O

O

OH

OH

HOOC

OHOH

O

O

OH

HOOC OH

OH

OH

HOOCO

OH

OH

OHOH

O

O

OCH 3OH

O

O

OH

OHHOOC

OH

OCH3OH

OO

OH

OHHOOC

OH

OCH 3OH

O

O

OHHOOC

OH

OH

OHOH

O

O

OH

HOOCOH

OHOH

O

O

OHOH

O

OOH

HOOC

OHOH

O

OOH

OH

O

O

O

OH

3-O-Caffeoylquinic acid 4-O-Caffeoylquinic acid 5-O-Caffeoylquinic acid

3-O-Feruloylquinic acid 4-O-Feruloylquinic acid 5-O-Feruloylquinic acid

3,4-O-Dicaffeoylquinic acid 3,5-O-Dicaffeoylquinic acid 4,5-O-Dicaffeoylquinic acid

Major chlorogenic acids found in coffee


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Found in oranges - hesperetin-7-O-rutinoside(hesperidin)

Hesperidin appears not to be absorbed in thesmall intestine

Some of the released aglycone is absorbed intothe circulatory via the formation of hesperetinglucuronide, in quantities corresponding to ca.5% of flavanone intake.

Citrus flavanones OO

HOHO

O

O

HO HOOH HO

OH

OH

O

OCH3

O

OH

1

2

345

6

7

81'

2'3'

4'

5'6'

A C

B

Hesperetin-7-O-rutinoside (hesperidin)
http://www.google.com.my/imgres?imgurl=http://www.shopolives.com/shop/images/uploads/FDA100_logo_green.jpg&imgrefurl=http://www.shopolives.com/shop/olives-glass-jar/cracked-green-olives-in-lemon-14-11-oz/prod_29.html&usg=__KJn6Vh5eJh87CQoiWTy57-Gq_7E=&h=82&w=80&sz=5&hl=en&start=7&um=1&itbs=1&tbnid=CaEzovTkOTT20M:&tbnh=75&tbnw=73&prev=/images%3Fq%3DFDA%2Bapproved%2Blogo%26um%3D1%26hl%3Den%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26tbs%3Disch:1


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Effect of food matricFood matrices e.g. carbohydrate, fat and protein
http://images.google.com.my/imgres?imgurl=http://www.happynews.com/living/chocolate/all-nestle-chocolate.jpg&imgrefurl=http://www.happynews.com/living/chocolate/all-nestle-chocolate.htm&usg=__3b5FpG_7XKdqgqnxzkGuqmBhFAw=&h=229&w=175&sz=12&hl=en&start=28&um=1&tbnid=NV3X6tNkfEVMlM:&tbnh=108&tbnw=83&prev=/images%3Fq%3Dchocolate%2Bnestle%26start%3D20%26ndsp%3D20%26um%3D1%26hl%3Den%26sa%3DNhttp://images.google.com.my/imgres?imgurl=http://www.guidaconsumatore.com/english/guides/food_beverage/chocolate-cocoa.jpg&imgrefurl=http://www.guidaconsumatore.com/english/guides/food_beverage/chocolate-cocoa.html&usg=__Iz1zE5IpaiVgdWdT-OEOaCvgVc8=&h=300&w=305&sz=31&hl=en&start=39&um=1&tbnid=1fosrRqWaimI6M:&tbnh=114&tbnw=116&prev=/images%3Fq%3Dcocoa%26start%3D20%26ndsp%3D20%26um%3D1%26hl%3Den%26rlz%3D1W1GGLR_en%26sa%3DN


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1% 31%

+


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Catabolism of cocoa flavan-3-ols

Food matrix effect
http://images.google.com.my/imgres?imgurl=http://www.sostav.ru/articles/eng/2005/09.12/news/images/almond.jpg&imgrefurl=http://www.sostav.ru/eng/news/2005/12/09/r1/&usg=__CH1TLGplv4sZvDorUAHgpzAnfBY=&h=297&w=450&sz=22&hl=en&start=53&um=1&tbnid=jUZ-XFFEChOpTM:&tbnh=84&tbnw=127&prev=/images%3Fq%3Dchocolate%2Bnestle%26start%3D40%26ndsp%3D20%26um%3D1%26hl%3Den%26sa%3DN


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Posses higher antioxidant activity than green

tea, wine and black tea

Cocoa products are currently controversialas to whether or not they should berecommended as health foods.

Cocoa contains high fat

Cocoa flavan-3-ols

O

OH

O

OH

4

8

OHOH

HO

OH OH

OH

OH

HO

O

OH

OHOH

HO

OH

4

O

OHHO

HO

OHOH

6

OH

HO O

OHOH

OH

OH

HO O

OHOH

OH

(+)-Catechin (+)-Epicatechin

(-)-Procyanidin B2 dimer

(-)-Procyanidin B5 dimer

Food matrix effect
http://images.google.com.my/imgres?imgurl=http://www.chocablog.com/wp-content/uploads/2008/08/nestle-heaven-vanilla-truffle-2.jpg&imgrefurl=http://www.chocablog.com/reviews/nestle-heaven-dark-vanilla-truffle/&usg=__PSECeUbIRpj5NzBrMmze1RmJRNI=&h=960&w=1280&sz=214&hl=en&start=27&um=1&tbnid=uvzK-Ah55-SemM:&tbnh=113&tbnw=150&prev=/images%3Fq%3Dchocolate%2Bnestle%26start%3D20%26ndsp%3D20%26um%3D1%26hl%3Den%26sa%3DN


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Is it really good ????

Teh tarikCarrot milk

Yoghurt with fruit

+

Green tea added with cholestrum
http://www.google.com.my/imgres?imgurl=http://www.teacuppa.com/img/products/Green-Tea-Powder.jpg&imgrefurl=http://www.teacuppa.com/Green-Tea-Powder.asp&usg=__Od4oJILss8yTnk4Spe2wnaD31Dw=&h=280&w=280&sz=20&hl=en&start=173&um=1&itbs=1&tbnid=6hN4f3q8-60SfM:&tbnh=114&tbnw=114&prev=/images%3Fq%3Dgreen%2Btea%26start%3D162%26um%3D1%26hl%3Den%26sa%3DN%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26ndsp%3D18%26tbs%3Disch:1http://www.google.com.my/imgres?imgurl=http://www.istockphoto.com/file_thumbview_approve/3841859/2/istockphoto_3841859-white-tea-green-tea-plant.jpg&imgrefurl=http://www.istockphoto.com/stock-photo-3841859-white-tea-green-tea-plant.php&usg=__ofOlddRf_j7PE8PKY3QsWISyhNU=&h=328&w=380&sz=42&hl=en&start=164&um=1&itbs=1&tbnid=5DrDkWGXUB8XIM:&tbnh=106&tbnw=123&prev=/images%3Fq%3Dgreen%2Btea%26start%3D162%26um%3D1%26hl%3Den%26sa%3DN%26rls%3Dcom.microsoft:*:IE-SearchBox%26rlz%3D1I7ADSA_en%26ndsp%3D18%26tbs%3Disch:1http://images.google.co.uk/imgres?imgurl=http://www.berryo.com.au/Image/yoghurt_fruit_salad_bowl.jpg&imgrefurl=http://www.berryo.com.au/default.asp%3Fid%3DBerryo&usg=__ZVfF_0IQpWLTXwvf2uERUXRBaiU=&h=324&w=250&sz=14&hl=en&start=1&um=1&itbs=1&tbnid=Q5dPDl_1J4Z16M:&tbnh=118&tbnw=91&prev=/images%3Fq%3Dyoghurt%2Bfruit%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26sa%3DN%26um%3D1


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How to overcome low absorption of

phenolics eg. flavonoids?


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Eat fruits!!
http://images.google.com.my/imgres?imgurl=http://www.the-m-studio.com/blog/rambutan.jpg&imgrefurl=http://saudijawa.blogspot.com/2008/04/wonderful-world-of-southeast-asian.html&usg=__b5Kj_jgQ-4tBn4ihSYmvjlpW4qI=&h=383&w=510&sz=32&hl=en&start=26&tbnid=TSBEopVyOm6nnM:&tbnh=98&tbnw=131&prev=/images%3Fq%3Drambutan%26gbv%3D2%26ndsp%3D20%26hl%3Den%26sa%3DN%26start%3D20http://images.google.com.my/imgres?imgurl=http://polkadotrobot.com/wp-content/uploads/2009/02/2-green-apples.jpg&imgrefurl=http://polkadotrobot.com/%3Fm%3D200902&usg=__z94mvv6CdUAnSB3MA8OJufrZP-0=&h=780&w=614&sz=28&hl=en&start=19&tbnid=hcYvGBw9auzdDM:&tbnh=142&tbnw=112&prev=/images%3Fq%3Dapples%26gbv%3D2%26hl%3Den%26sa%3DG


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Fruit contains vitamin

and free antioxidant

compound highlyabsorped
http://images.google.com.my/imgres?imgurl=http://www.the-m-studio.com/blog/rambutan.jpg&imgrefurl=http://saudijawa.blogspot.com/2008/04/wonderful-world-of-southeast-asian.html&usg=__b5Kj_jgQ-4tBn4ihSYmvjlpW4qI=&h=383&w=510&sz=32&hl=en&start=26&tbnid=TSBEopVyOm6nnM:&tbnh=98&tbnw=131&prev=/images%3Fq%3Drambutan%26gbv%3D2%26ndsp%3D20%26hl%3Den%26sa%3DN%26start%3D20http://images.google.com.my/imgres?imgurl=http://polkadotrobot.com/wp-content/uploads/2009/02/2-green-apples.jpg&imgrefurl=http://polkadotrobot.com/%3Fm%3D200902&usg=__z94mvv6CdUAnSB3MA8OJufrZP-0=&h=780&w=614&sz=28&hl=en&start=19&tbnid=hcYvGBw9auzdDM:&tbnh=142&tbnw=112&prev=/images%3Fq%3Dapples%26gbv%3D2%26hl%3Den%26sa%3DG


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Phenolic acids

a. Contribute one-third of the dietary phenols in plant foodsb. Antioxidant properties and beneficial health-promoting effects in chronic

and degenerative diseases.c. Free phenolic acid -well absorbed, better than flavonoids

e.g 5 to 30 minutes compared to 8-24 hrs for flavonoidd. Higher antioxidant capacity than flavonoids

e.g. gallic acid (14 x higher than vit. E)pyrogallic acidprotocatechuic acid (10 x higher than vit. E)

OHOH


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Phenolic acidsO

OH

O

OH

4

8

OH

OH

HO

OH OH

OH

OH

HO

O

OH

OHOH

HO

OH

4

O

OHHO

HO

OH

OH

6

OH

HO O

OH

OH

OHOH

HO O

OH

OH

OH

( )-Epicatechin(+)-Catechin

( )-Procyanidin B2 dimer ( )-Procyanidin B5 dimer

Phenolic acids

microorganism
http://images.google.co.uk/imgres?imgurl=http://jihyelikesfood.files.wordpress.com/2009/03/dean-and-deluca-soy-sauce1.jpg&imgrefurl=http://jihyelikesfood.wordpress.com/2009/03/14/soy-sauce/&usg=__ifnvWfLdvrTvH46FnIq7PlRY81o=&h=300&w=300&sz=28&hl=en&start=8&um=1&itbs=1&tbnid=JVbPZDso42gzcM:&tbnh=116&tbnw=116&prev=/images%3Fq%3Dsoy%2Bsauce%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26sa%3DN%26um%3D1http://images.google.co.uk/imgres?imgurl=http://www.changetovegan.com/wp-content/uploads/2009/06/tempeh.jpg&imgrefurl=http://www.changetovegan.com/2009/06/tempeh-delight/&usg=__9dEmnBFfKH-Oji-U4fIUd29_ies=&h=254&w=285&sz=6&hl=en&start=7&um=1&itbs=1&tbnid=rYizscryDNjZEM:&tbnh=102&tbnw=115&prev=/images%3Fq%3Dtempeh%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26um%3D1http://images.google.co.uk/imgres?imgurl=http://www.pillfreevitamins.com/images/colon.jpg&imgrefurl=http://www.pillfreevitamins.com/coloncleanse.htm&usg=__6xABf0u1-dOF9l0z08RIEpLXi3E=&h=263&w=350&sz=16&hl=en&start=8&um=1&itbs=1&tbnid=kOBDMrFQJ-FEYM:&tbnh=90&tbnw=120&prev=/images%3Fq%3Dcolon%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26sa%3DN%26um%3D1


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Colon

Flavonoids

Phenolic acids (5 to 30 hrs)

High free phenolicacids juice

5 to 30 min.absorption
http://images.google.com.my/imgres?imgurl=http://www.ieoonions.com/images/sales/yellow_onion.jpg&imgrefurl=http://www.economicefficiency.blogspot.com/&usg=__-RDshDYQ8gNDlg3OvEL6EEHwIUg=&h=1709&w=1565&sz=192&hl=en&start=2&um=1&tbnid=aX81ivwqWfr4JM:&tbnh=150&tbnw=137&prev=/images%3Fq%3Donion%26um%3D1%26hl%3Den%26rlz%3D1W1GGLR_en%26sa%3DGhttp://images.google.com.my/imgres?imgurl=http://www.kadagan.bz.tc/images/citrus.jpg&imgrefurl=http://www.kadagan.bz.tc/custom2.html&usg=__JMvUBtXtPPqPlPdqC6iP30sGEa4=&h=216&w=319&sz=33&hl=en&start=226&tbnid=zCsdteAtAyEzkM:&tbnh=80&tbnw=118&prev=/images%3Fq%3Dcitrus%2Bfruit%26start%3D220%26gbv%3D2%26ndsp%3D20%26hl%3Den%26sa%3DNhttp://www.mdhb.com/images/raspberry1.jpg


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Free phenolic acids in hone
http://images.google.co.uk/imgres?imgurl=http://www.thedailygreen.com/cm/thedailygreen/images/Dz/honey-super-food-lg.jpg&imgrefurl=http://www.thedailygreen.com/healthy-eating/eat-safe/super-foods-44030408&usg=__EQ8l3keyz2-TXRXLuyFygN-ezBk=&h=360&w=460&sz=17&hl=en&start=193&um=1&itbs=1&tbnid=yPCrOXfjE3gGUM:&tbnh=100&tbnw=128&prev=/images%3Fq%3Dhoney%26ndsp%3D20%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26sa%3DN%26start%3D180%26um%3D1http://images.google.co.uk/imgres?imgurl=http://www.igourmet.com/images/topics/honey1.jpg&imgrefurl=http://www.igourmet.com/honey.asp&usg=__8IWCi5k7ppit8fEsMS2tMNIIVoE=&h=325&w=325&sz=80&hl=en&start=182&um=1&itbs=1&tbnid=fvumBMwboEO1pM:&tbnh=118&tbnw=118&prev=/images%3Fq%3Dhoney%26ndsp%3D20%26hl%3Den%26rlz%3D1T4ADSA_enMY340MY341%26sa%3DN%26start%3D180%26um%3D1


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031.2

3.3

134

29.2

375.1

573.4

0

100

200

300

400

500

600

Totalfreephe

nolicac

Product A Product B Product C Product D Product E Product F Nutrima-

Juice

Free phenolic acid in commercial products and

Nutrima-Juice

high free antioxidant

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