• 50,000 strokes – ¼ under age 55

• 10,000 dead – No. 3

• 20,000 disabled – No. 1

Imaging the Penumbra

No penumbra = no benefit likely

Translation – animal to human

Imaging the vessels

Better clot busting drugs

• TNK

• DSP

Better access to proven therapies

Number needed to transport = 2.5