how cells communicate cell signaling. learning objectives how do cells communicate long and short...

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HOW CELLS COMMUNICATE Cell Signaling

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Page 1: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

HOW CELLS COMMUNICATE

Cell Signaling

Page 2: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

Learning Objectives

How do cells communicate long and short distances?

What are the 3 stages of cell signaling?What is involved in each of the 3 stages of

cell signaling?

Page 4: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

Local Regulators

Direct Contact Cell junctions Cell-cell recognition

Paracrine Growth factors cause cells

to grow and multiplySynaptic

Nervous system Electrical signal triggers

chemical signal – neurotransmitters

Signaling

Page 5: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

Long-Distance

Hormones “endocrine signaling” Cells release hormone

molecules into blood vessels where they travel to other parts of the body

Plant hormones can travel through cells, or through air as a gas

Vary a lot in size & type: ethylene vs. insulin

Signaling

Page 6: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

Three Stages of Cell Signaling

A Preview…

1. Reception A chemical signal is “detected”

when it binds to a receptor protein on the cell’s surface or inside the cell.

Page 7: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

Three Stages of Cell Signaling

A Preview…

2. Transduction The receptor protein changes in

response to the signal and initiates the process of converting the signal to a form that can bring about the response.

Can be a single step or a sequence of changes in multiple molecules (“signal transduction pathway”)

Page 8: HOW CELLS COMMUNICATE Cell Signaling. Learning Objectives How do cells communicate long and short distances? What are the 3 stages of cell signaling?

Three Stages of Cell Signaling

A Preview…

3. Response Any cellular activity Must happen in the right cells, at

the right time, and in coordination with other cells of the organism