how cells communicate cell signaling. learning objectives how do cells communicate long and short...
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HOW CELLS COMMUNICATE
Cell Signaling
Learning Objectives
How do cells communicate long and short distances?
What are the 3 stages of cell signaling?What is involved in each of the 3 stages of
cell signaling?
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Cell Communication Video
Local Regulators
Direct Contact Cell junctions Cell-cell recognition
Paracrine Growth factors cause cells
to grow and multiplySynaptic
Nervous system Electrical signal triggers
chemical signal – neurotransmitters
Signaling
Long-Distance
Hormones “endocrine signaling” Cells release hormone
molecules into blood vessels where they travel to other parts of the body
Plant hormones can travel through cells, or through air as a gas
Vary a lot in size & type: ethylene vs. insulin
Signaling
Three Stages of Cell Signaling
A Preview…
1. Reception A chemical signal is “detected”
when it binds to a receptor protein on the cell’s surface or inside the cell.
Three Stages of Cell Signaling
A Preview…
2. Transduction The receptor protein changes in
response to the signal and initiates the process of converting the signal to a form that can bring about the response.
Can be a single step or a sequence of changes in multiple molecules (“signal transduction pathway”)
Three Stages of Cell Signaling
A Preview…
3. Response Any cellular activity Must happen in the right cells, at
the right time, and in coordination with other cells of the organism
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Signal Transduction Video