hsv treatment by aseem
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TRANSCRIPT
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MANAGEMENT REGIMES FOR HERPES SIMPLEX INF
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SYMPTOMATIC MANAGEMENT• Maintain Hygeine, Keep area dry and clean
• Treatment indicated in case of Persistence, Burning / Pain / Fever, Superadded infection,
• TOPICALS DOCOSANOL 10% CREAM LA 5 TIMES DAILY X 07-10 DAYS PENCICLOVIR 1% CREAM LA q 2 hrs X 07-10 DAYS ACYCLOVIR 5% CREAM LA 5 TIMES DAILY X 07-10 DAYS (Muco-adhesive Buccal Tablet (Sitavig 50mg) Single dose to Canine Fossa)
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SYSTEMIC ANTIVIRALSREDUCTION :
Healing time of lesions 16 12 days 07 05 days
Post-herpetic pain 07 05 days04 02 days
Constitutional symp 06 03 days04 03 days
No effect on Latency
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ORO-FACIAL HERPES
PRIMARY INFECTION
T ACYCLOVIR 400 mg TDS X 07-10 daysT VALACYCLOVIR 1 g BD X 07-10 daysT FAMCICLOVIR 250 mg TDS X 07-10 days
ACYCLOVIR 15 mg/kg/dose 5 times a day x 07-10 days (Pediatric)
Also for Herpes Gladiatorum / Whitlow / Scrumpox
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ORO-FACIAL HERPES
• RECURRENT : EPISODIC
T ACYCLOVIR 400 mg 5 times a day X 04-05 dT VALACYCLOVIR 2 g BD X 01 dT FAMCICLOVIR 500 mg TDS X 01 d
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ORO-FACIAL HERPES
• RECURRENT : SUPPRESSION
T ACYCLOVIR 400 mg BD x 12 months
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GENITAL HERPES (CDC-2010)
• PRIMARY INFECTION
T ACYCLOVIR 400 mg TDS X 07-10 daysT VALACYCLOVIR 1 g BD X 07-10 daysT FAMCICLOVIR 250 mg TDS X 07-10 days
Extended > 10 days if inadequate healing
ACYCLOVIR 15 mg/kg/dose 5 times a day x 07-10 days (Pediatric)
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GENITAL HERPES
• RECURRENT : EPISODIC
T ACYCLOVIR 400 mg TDS X 05 dT VALACYCLOVIR 1g OD X 05 dT FAMCICLOVIR 125 mg BD X 05 d
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GENITAL HERPES
• RECURRENT : SUPPRESSION
T ACYCLOVIR 400 mg BD X 12 monthsT VALACYCLOVIR 500 mg BD X 12 monthsT FAMCICLOVIR 250 mg TDS X 12 months
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GENITAL HERPES
• RECURRENT : SUPPRESSION in PREGNANCY
T ACYCLOVIR 400 mg TDS 36th Week of Gestation till Delivery
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OCULAR HERPES
• PRIMARY INFECTION
T ACYCLOVIR 400 mg 5 times a dayT VALACYCLOVIR 1 gm BD
Topical 1 % ED TRIFLURIDINE, 0.1 % ED IDOXURIDINE or 0.5 % Ointment, 3 % Ointment VIDARABINE q 2 hrs Day + q 4 hrs Night
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OCULAR HERPES
• RECURRENCE : SUPPRESSION
T ACYCLOVIR 400 mg TDS X 12 months
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NEONATAL HERPES
• Inj ACYCLOVIR 20 mg/kg/dose TDSx 02 – 03 weeks
(Max 80 mg/kg/day)
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ECZEMA HERPETICUM
T ACYCLOVIR 400 mg TDS X 14-21 daysT VALACYCLOVIR 1 g BD X 14-21 daysT FAMCICLOVIR 250 mg TDS X 14-21 days
Inj ACYCLOVIR 10-15 mg/kg/dose TDS X 02 -03 weeks
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HERPES SIMPLEX ENCEPHALITIS
• Inj ACYCLOVIR IV10-15 mg/kg/dose TDS X 14-21 days
Also for Disseminated Herpes Simplex Inf
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THANK YOU