Humidification and Evaporative Cooling

HUMIDIFICATION IN PHARMACEUTICAL MANUFACTURING

Condair humidifiers are used inpharmaceutical processing andresearch facilities around the world tomaintain product quality, reduce wasteand enhance productivity.

Some of the world’s leadingpharmaceutical manufacturers puttheir trust in Condair humidificationsystems to help them meet theirproduction objectives.

TRUSTED TECHNOLOGY

Condair has manufacturing facilities inAsia, North America and Europe as wellas sales operations in 15 countries anddistributors in over 40 more.

The company has been serving theglobal pharmaceutical industry formore than 60 years and is highlyexperienced in many differentprocessing technologies, products,climates and all types ofpharmaceutical production andresearch facility.

Condair humidification systems aredesigned for each individualapplication by pharmaceuticalhumidification experts to create theideal production environment.

If required, Condair’s regional R&Ddepartments can work with a client’sproduct development team, creatingcustom solutions to meet FDA or GAMP compliance.

Alongside system design, manufactureand supply, Condair’s specialisthumidification engineering teams offerinstallation, commissioning,maintenance and spares supply.

System maintenance from Condairprovides the manufacturer’s expertisedirectly on-site, ensuring criticalapplications have the exceptionalsupport they require.

GLOBAL EXPERTISE, LOCAL SOLUTIONS

GlaxoSmithKline, UK

Pfizer, UK

Eli Lilly, UK

AstraZeneca, UK

Boston Scientific, Ireland

Abbott Laboratories, Ireland Roche Penzeberg, Germany

Bristol-Myers Squibb, Germany

GE Healthcare, Austria

Roche Kaiseraugust, SwitzerlandAstellas Pharma Europe, Netherlands

TEVA Pharmachemie, Netherlands

DSM, Netherlands

Novo Nordisk Pharmaceuticals Co Ltd, China

Xian Janssen Pharmaceuticals Ltd, China

Sanofi (Beijing) Pharmaceuticals Co Ltd, China

Beijing Novartis Pharmaceuticals Co Ltd, China

Taizhou Astra Zeneca Pharmaceuticals Co Ltd, China

Teva and Taro, Israel

Neopharma, United Arabic Emirates

QG Medical Devices, Qatar

Spimaco, Saudi Arabia

Nobel and World Medicine, Turkey

Sanofi Aventis Vostok, Russia

TEVA, Russia

Promega Corporation, USA

SPL, USA

Pfizer, USA

Incyte Pharmaceutical, USA

Kremers Urban Pharmaceuticals, USA

MEDCO/Express Scripts, USA

Purdue Heine Pharmacy, USA

St Francis Hospital Pharmacy, USA

Beckman Coulter, USA

Pfizer, Venezuela

Elanco, Canada

Cipla, India

Lupin, India

Zydus Cadila, India

Pharma Spec, South Africa

Adcock Ingram, South Africa

Biovac, South Africa

Torrent Pharma, India

Pharmaxis, Australia

GlaxoSmithKline, Australia

Pfizer, Australia

Reckets Benckaiser, Australia

Apotex, Canada

Laboratorios Bayer, Spain

Laboratorios Beechmann, Spain

Picking Farma, Spain

Productos Roche S.A., Spain

OPTIMUM HUMIDITY IMPROVES PRODUCTIVITYHumidity control in the pharmaceutical industry is essential in many productionand testing processes to maintain quality and reduce waste.

Tablet coatingSuccessful coating of a tablet largelydepends on the composition of thetablet at the time of exposure to itscoating. If the tablet’s surface is too dry,due to incorrect humidity levels, thecoating will not adhere correctly.Likewise if the humidity post coating isnot optimal, the coating may dry toorapidly, detrimentally affecting itsproperties.

CleanroomsMany cleanroom manufacturingprocesses require control overhumidity. For instance, the printing ofdiagnostic strips using water basedinks can require a high humidity ofbetween 95-98%RH, ±1%RH. In suchcircumstances, when the optimumhumidity is so precise, it is often notpossible to maintain a whole room atsuch a close level so a contained micro-climate can be produced around anindividual manufacturing process.

Fluid Bed DryingConsistent and responsive humiditycontrol in FBD processes results in theproduct’s moisture content reachingthe target level more rapidly and withless wastage through over or underdrying. Close control steam humidifiersrunning on pure RO water can provide±2%RH and increase productivity whencompared to more tradition live steamhumidifiers mounted on fluid bed driers.

Stability testingRegulations on accelerated or long-term stability testing mostly requirehumidity to be controlled within atolerance of ±5%RH. If the condition ofthe atmosphere falls outside thiswindow, it can result in a test having tobe restarted. This is expensive and caneven delay the launch of a newproduct.

Static preventionLevels of humidity below 40%RH canlead to static build-up. The results ofthis include materials adhering to eachother on the production line and notlocating correctly inside of packaging.

A humidity level of between 55-65%RHwill significantly reduce the probabilityof electro static discharge, which isvital for sensitive electronic equipmentor where flammable gases orsubstances are being used.

Condair has a wide range ofhumidification systems to suit anypharmaceutical manufacturing orresearch facility. As well as close controlsteam systems, the range includes lowenergy adiabatic humidifiers that canreduce operating costs and a building’scarbon footprint.

Often the type of humidity controlrequired by pharmaceutical processesis not achievable with standardhumidifiers intended for offices ortypical manufacturing environments.Many models within the Condair rangehave options specifically designed foradvanced process applications.

This specialist range is combined withextensive expertise in the industry toensure Condair always recommendsand provides the most appropriatesolution for any pharmaceuticalproject.

SOLUTIONS FOR THE PHARMACEUTICAL INDUSTRY

ASK FOR A FREE EXPERT CONSULTATION

Condair RS – resistive steam humidifier Condair ESCO – live steam humidifier

Condair GS – gas-fired humidifier Condair ME – evaporative humidifier

12/2018

Condair plcArtex Avenue, Rustington, Littlehampton, West Sussex, BN16 3LN, UKTel: +44 (0)1903 850200 - uk.sales@condair.com - www.condair.co.uk