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Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry

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Page 1: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Hyperbilirubinemia

Web Meeting

2018

Dr. Ann Anderson Berry

Page 2: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Introduction

Page 3: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Objective

• Describe evidence-based practices (EBP) to prevent

hyperbilirubinemia and kernicterus

Page 4: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

• All newborns will have a prn bilirubin order (TSB or TCB) to

be initiated at the nurse’s discretion (AAP)

-Visual assessment not accurate (Keren)

AAP (2004). Management of Hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics, 114(1),297-316. DOI:

10.1542/peds.114.1.297.

Keren, R., Luan, X., Friedman, S., Saddlemire, S., Cnaan, A., & Bhutani, V. K. (2008). A comparison of alternative risk-assessment strategies

for predicting significant neonatal hyperbilirubinemia in term and near-term infants. Pediatrics, 121(1), e170-9.

EBP

Page 5: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

• Universal predischarge bilirubin screening-TSB or TcB

• Use of clinical risk factors and predischarge bili to predict risk

of hyperbilirubinemia

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in the newborn infant ≥ 35

weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198. DOI:10.1542/peds.2009-0329

Bhutani, V. K., Stark, A. R., Lazzeroni, L. C., Poland, R., Gourley, G. R., Kazmierczak, S., . . . Stevenson, D. K. (2013). Predischarge

screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics, 162(3), 477-482.e1.

10.1016/j.jpeds.2012.08.022

EBP

Page 6: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

AAP (2004). Management of Hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.

Pediatrics, 114(1),297-316. DOI: 10.1542/peds.114.1.297.

Risk Factors

Page 7: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te

newborn infant ≥ 35 weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198.

DOI:10.1542/peds.2009-0329

Risk Factors

Page 8: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

• Use hour-specific nomogram to interpret bili (Maisels 2009, AAP 2004)

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te newborn infant ≥ 35

weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198. DOI:10.1542/peds.2009-0329

AAP (2004). Management of Hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics, 114(1),297-316. DOI:

10.1542/peds.114.1.297.

EBP

Page 9: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te

newborn infant ≥ 35 weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198.

DOI:10.1542/peds.2009-0329

Page 10: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

www.bilitool.org

Page 11: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,
Page 12: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,
Page 13: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,
Page 14: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Recommendations for Management and Follow-up

EBP

Page 15: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te

newborn infant ≥ 35 weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198.

DOI:10.1542/peds.2009-0329

Page 16: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te

newborn infant ≥ 35 weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198.

DOI:10.1542/peds.2009-0329

Page 17: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te

newborn infant ≥ 35 weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198.

DOI:10.1542/peds.2009-0329

Page 18: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Copyright ©2004 American Academy of Pediatrics

Subcommittee on Hyperbilirubinemia, Pediatrics 2004;114:297-316

Guidelines for phototherapy in hospitalized infants of 35 or more weeks' gestation

Page 19: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Maisels, M.J., Bhutani, V.k., Bogen, D., Newman, T.B., Start, A.R., & Watchko, J.F. (2009).Hyperbilirubinemia in te

newborn infant ≥ 35 weeks gestation: An update with clarifications. Pediatrics, 124(4), 1193-1198.

DOI:10.1542/peds.2009-0329

Recommendations for Management and Follow-up

Page 20: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

• Written and verbal info to parents at discharge explaining

jaundice and need to monitor for (AAP, 2004)

AAP (2004). Management of Hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics, 114(1),297-316. DOI:

10.1542/peds.114.1.297.

EBP

Page 21: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

SUMMARY

• TSB or TcB if any jaundice noted visually (AAP, Keren) to be initiated by the nurse (NANN 2010)

• Use of clinical risk factors and predischarge bili to predict risk of hyperbilirubinemia (Maisels)

• Universal predischarge bilirubin screening-TSB or TcB (Maisels)

• Use hour-specific nomogram to interpret bili (Maisels 2009, AAP 2004)

• Written and verbal info to parents at discharge explaining jaundice and need to monitor for (AAP 2004)

• Follow up post discharge per algorithm (Maisels 2009)

Page 22: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

• G1P0

• 36 5/7 wks gestation

• Hispanic

• PROM

• Apgars 7 & 9

• AB pos

• SVD after 20 hour

labor with oxytocin

• Formula feeding

• Universal bili screen

at 24h with newborn

screen was 10.6

(TSB)

Case 1

Page 23: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Copyright ©2004 American Academy of Pediatrics

Subcommittee on Hyperbilirubinemia, Pediatrics 2004;114:297-316

Guidelines for phototherapy in hospitalized infants of 35 or more weeks' gestation

Page 24: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

G4P3

39 weeks

gestation

Caucasian

SVD after 2 hour

labor

O pos

Apgars 9 & 9

Breastfeeding well

Case 2

Page 25: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Post Discharge:

• ER visit 48 hours after discharge (72 hours of life) for poor

feeding – PE Jaundiced

• Bilirubin 24

Page 26: Hyperbilirubinemia Web Meeting 2018 Dr. Ann Anderson Berry · screening for severe neonatal hyperbilirubinemia identifies infants who need phototherapy. The Journal of Pediatrics,

Questions Can be

Directed to Peggy Brown

or Ann Anderson Berry

through NPQIC.org