hypertension guidelines amga plank 2

51
Hypertension Guidelines and Adherence AMGA Plank 2 Emil Thattassery MD MPH Division of Cardiology Chief of Medical Specialties, Baltimore Mid-Atlantic Permanente March 21 st , 2013

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Page 1: Hypertension Guidelines AMGA Plank 2

Hypertension Guidelines

and Adherence

AMGA Plank 2

Emil Thattassery MD MPH

Division of Cardiology

Chief of Medical Specialties Baltimore

Mid-Atlantic Permanente

March 21st 2013

Disclosures

I have no financial disclosures

No personal financial interests stock ownership

interests or industry relationships

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Importance

High blood pressure is ubiquitous

bull 1 out of 3 US adults (68 million adults) have high blood pressure

ndash 36 million adults still have uncontrolled BP

ndash 30 of people with hypertension in US are unaware of it

bull Lifetime risk of HTN is approximately 85-90 (by age 80-85)

ndash 75 of adults older than 75yrs have HTN

High blood pressure is deadly

bull Lowering SBP by 12mmHg over 10yrs in patient with CV risk

factors ndash can prevent 1 death for every 11 patients

High blood pressure is costly

bull Costs the nation almost $131 billion annually in direct medical

expenses and $25 billion in lost productivity

CDC 2011 NHANES

JNC 7

Blood Pressure Definitions

Definition

bull Average of two or more properly measured seated BP

readings on each of two or more office visits

Goals of Therapy (JNC7)

bull BP goal lt14090

bull For patients with diabetes renal disease goal lt13080

JNC8 still to be released

bull JNC7 was released 2003 now 10 years old

bull JNC8 will be based on rigorous clinical evidence review

bull Guidelines to be released on HTN Hyperlipidemia Obesity

JNC 7

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 2: Hypertension Guidelines AMGA Plank 2

Disclosures

I have no financial disclosures

No personal financial interests stock ownership

interests or industry relationships

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Importance

High blood pressure is ubiquitous

bull 1 out of 3 US adults (68 million adults) have high blood pressure

ndash 36 million adults still have uncontrolled BP

ndash 30 of people with hypertension in US are unaware of it

bull Lifetime risk of HTN is approximately 85-90 (by age 80-85)

ndash 75 of adults older than 75yrs have HTN

High blood pressure is deadly

bull Lowering SBP by 12mmHg over 10yrs in patient with CV risk

factors ndash can prevent 1 death for every 11 patients

High blood pressure is costly

bull Costs the nation almost $131 billion annually in direct medical

expenses and $25 billion in lost productivity

CDC 2011 NHANES

JNC 7

Blood Pressure Definitions

Definition

bull Average of two or more properly measured seated BP

readings on each of two or more office visits

Goals of Therapy (JNC7)

bull BP goal lt14090

bull For patients with diabetes renal disease goal lt13080

JNC8 still to be released

bull JNC7 was released 2003 now 10 years old

bull JNC8 will be based on rigorous clinical evidence review

bull Guidelines to be released on HTN Hyperlipidemia Obesity

JNC 7

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 3: Hypertension Guidelines AMGA Plank 2

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Importance

High blood pressure is ubiquitous

bull 1 out of 3 US adults (68 million adults) have high blood pressure

ndash 36 million adults still have uncontrolled BP

ndash 30 of people with hypertension in US are unaware of it

bull Lifetime risk of HTN is approximately 85-90 (by age 80-85)

ndash 75 of adults older than 75yrs have HTN

High blood pressure is deadly

bull Lowering SBP by 12mmHg over 10yrs in patient with CV risk

factors ndash can prevent 1 death for every 11 patients

High blood pressure is costly

bull Costs the nation almost $131 billion annually in direct medical

expenses and $25 billion in lost productivity

CDC 2011 NHANES

JNC 7

Blood Pressure Definitions

Definition

bull Average of two or more properly measured seated BP

readings on each of two or more office visits

Goals of Therapy (JNC7)

bull BP goal lt14090

bull For patients with diabetes renal disease goal lt13080

JNC8 still to be released

bull JNC7 was released 2003 now 10 years old

bull JNC8 will be based on rigorous clinical evidence review

bull Guidelines to be released on HTN Hyperlipidemia Obesity

JNC 7

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 4: Hypertension Guidelines AMGA Plank 2

Importance

High blood pressure is ubiquitous

bull 1 out of 3 US adults (68 million adults) have high blood pressure

ndash 36 million adults still have uncontrolled BP

ndash 30 of people with hypertension in US are unaware of it

bull Lifetime risk of HTN is approximately 85-90 (by age 80-85)

ndash 75 of adults older than 75yrs have HTN

High blood pressure is deadly

bull Lowering SBP by 12mmHg over 10yrs in patient with CV risk

factors ndash can prevent 1 death for every 11 patients

High blood pressure is costly

bull Costs the nation almost $131 billion annually in direct medical

expenses and $25 billion in lost productivity

CDC 2011 NHANES

JNC 7

Blood Pressure Definitions

Definition

bull Average of two or more properly measured seated BP

readings on each of two or more office visits

Goals of Therapy (JNC7)

bull BP goal lt14090

bull For patients with diabetes renal disease goal lt13080

JNC8 still to be released

bull JNC7 was released 2003 now 10 years old

bull JNC8 will be based on rigorous clinical evidence review

bull Guidelines to be released on HTN Hyperlipidemia Obesity

JNC 7

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 5: Hypertension Guidelines AMGA Plank 2

JNC 7

Blood Pressure Definitions

Definition

bull Average of two or more properly measured seated BP

readings on each of two or more office visits

Goals of Therapy (JNC7)

bull BP goal lt14090

bull For patients with diabetes renal disease goal lt13080

JNC8 still to be released

bull JNC7 was released 2003 now 10 years old

bull JNC8 will be based on rigorous clinical evidence review

bull Guidelines to be released on HTN Hyperlipidemia Obesity

JNC 7

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 6: Hypertension Guidelines AMGA Plank 2

Blood Pressure Definitions

Definition

bull Average of two or more properly measured seated BP

readings on each of two or more office visits

Goals of Therapy (JNC7)

bull BP goal lt14090

bull For patients with diabetes renal disease goal lt13080

JNC8 still to be released

bull JNC7 was released 2003 now 10 years old

bull JNC8 will be based on rigorous clinical evidence review

bull Guidelines to be released on HTN Hyperlipidemia Obesity

JNC 7

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 7: Hypertension Guidelines AMGA Plank 2

Hypertension JNC7 Classification

JNC 7

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 8: Hypertension Guidelines AMGA Plank 2

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 9: Hypertension Guidelines AMGA Plank 2

JNC 7

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 10: Hypertension Guidelines AMGA Plank 2

JNC 7 Pharmacologic choices

Pharmacologic recommendations from JNC 7

bull First-line ndash diuretic therapy preferred

ndash HCTZ (25-50mg) or Chlorthalidone (125-25mg)

bull Combination therapy

ndash gt23 of patients cannot be controlled on one drug

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 11: Hypertension Guidelines AMGA Plank 2

JNC 7

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 12: Hypertension Guidelines AMGA Plank 2

JNC 7

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 13: Hypertension Guidelines AMGA Plank 2

Resistant Hypertension

Resistant HTN

bull Defined as adherence to 3 drug regimen (including diuretic)

bull Causes

ndash Improper BP measurement

ndash White Coat Hypertension

ndash Heavily calcified brachial arteries

ndash Inadequate diuretic dose (CKD CHF)

ndash NSAIDS OTC cold products (pseudoephedrine)

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 14: Hypertension Guidelines AMGA Plank 2

Causes of Resistant Hypertension

Drug-related causes

58

Nonadherence 16

Unknown 6

Office resistance

6

Psychological causes

9

Secondary HTN 5

Interfering substances

1

Primary cause of resistant hypertension Garg JP et al Am J Hypertens 200316925-930

Suboptimal regimen

Medication intolerance

Drug interactions

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 15: Hypertension Guidelines AMGA Plank 2

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 16: Hypertension Guidelines AMGA Plank 2

Recent Clinical Evidence

ACCORD-BP (NEJM 2010)

bull 4733 pts DM2 x 47yrs ndash goal BPlt120 vs lt140

ndash Mean BP attained 1193 vs 1335 (vs 13976 baseline)

bull No diff MICVAdeath (187 vs 209)

bull No difference in all cause mortality (128 vs 119)

ndash Reduction in stroke (032 vs 053)

ndash Side effects (ie syncopedizziness) (33 vs 13)

HYVET (NEJM lsquo08)

bull 3800pt x 18yrs gt80yrs goal SBPlt150 with diuretic+- ACE

bull Decreased CVA (30) CHF (64) all cause mortality (21)

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 17: Hypertension Guidelines AMGA Plank 2

Recent Statements

Diabetics Blood Pressure Treatment Goals

bull ADA (2013) ndash BP lt14080

bull NICE (2011) ndash BPlt14090 (DMCKDCVD)

bull ESH (2009) ESC (2012) ndash BPlt14090

Elderly Blood Pressure Treatment Goals

bull ACCFAHA (2011) gt80 yrs ndash SBP lt150

bull NICE (2011) ndash gt80 yrs - BPlt15090

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 18: Hypertension Guidelines AMGA Plank 2

Speculations for JNC 8

Changes in BP goals (DM CKD elderly)

Expanding first line preferred agents

bull Thiazide diuretic is currently the preferred agent may expand

to CCBACEARB in future

Ambulatory BPs vs In-office readings

Combination therapy

bull Two drugs are better than doubling dose

Chlorthalidone vs HCTZ

bull Differences between agents may be dose related (HCTZ 50

is similar efficacy to Chlorthalidone 25)

Aldactone as add-on agent for resistant HTN

Sodium dietary targets

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 19: Hypertension Guidelines AMGA Plank 2

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 20: Hypertension Guidelines AMGA Plank 2

Challenges to Adherence

Obesity

bull 68 of US adults are overweight or obese (35 obese)

bull 32 of US children are overweight or obese (17 obese)

Diet

bull Less than 1 of US adults meet the definition of ldquoIdeal

Healthy Dietrdquo

bull Essentially no children meet the goal

Exercise

bull 32 of adults report no aerobic activity at all

bull Only 21 of adults meet guidelines for physical activity

Medications

bull Studies indicate up to 50 of patients do not take their

medications as prescribed

AHA Circ 2013

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 21: Hypertension Guidelines AMGA Plank 2

Improving Adherence

Patient factors

bull Patient education developing insight into condition

ndash Patients usually feel well

ndash Perceived side effects to medications

bull Depression

bull Family members social support

Physician factors

bull Truly believing in importance of goals

ndash Nonadherence is 19 higher in patients whose physician

communicates poorly

bull Conveying empathy concern

bull Correctly identifying patient barriers

bull Including patient into decision making

bull Acknowledging patient successes adherence

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 22: Hypertension Guidelines AMGA Plank 2

Improving Adherence

Simplifying Medical Regimen

bull Low cost medications

bull Once daily meds

ndash 8 greater adherence with once a day dosing

bull Recognize Nonadherence

Follow-up

bull Make next appointment before patient leaves office

bull Use appointment reminders

bull Follow-up on patients who miss appointments

bull Collaboration with dieticians nurses NPs PAs pharmacists

Clin Ther 2002 24302

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 23: Hypertension Guidelines AMGA Plank 2

Overview

Background

Definitions

Treatment Guidelines (JNC 7) bull Non-pharmacologic

bull Pharmacologic

bull Resistant Hypertension

Recent Clinical Data and Recommendations

Optimizing Adherence to Therapy

Case Study ndash Kaiser Permanente (Mid-Atlantic)

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 24: Hypertension Guidelines AMGA Plank 2

The Kaiser Experience

Implementing Blood Pressure Control

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 25: Hypertension Guidelines AMGA Plank 2

KP Initial challenges

In 2001 Kaiser Permanente ranked below the 25th

percentile for HEDIS BP measures by NCQA

bull lt50 of KP members had BP under control

Blood Pressure control became a top priority by KP

Leadership

bull Implementation assisted by subsequent adoption of

electronic medical records system (Epic implemented in

2005)

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 26: Hypertension Guidelines AMGA Plank 2

Blood Pressure ndash Implementation

Benchmarking

bull Sharing and comparing performance other Kaiser regions

and other organizations across the US

Transparency

bull Sharing performance monthly to region center provider

bull 2010 ndash Electronic panel management tool

ndash Providers can search and directly link to patients with

uncontrolled BP

ndash All MDs can view data not password protected

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 27: Hypertension Guidelines AMGA Plank 2

Transparency

Performance Reporting Panel Mgmt

By Center Individual Physicians

By Area

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 28: Hypertension Guidelines AMGA Plank 2

Blood Pressure ndash Implementation

Education

bull Training staff annually for BP measurement competency

bull Quarterly Webinars Quality Newsletters

bull Member education ndash pamphlets classes online education

bull Sharing best practices from local regional and national high

performers

ndash Disseminating best practices across Kaiser regions

throughout country

Reliability ndash creating effective and simple workflows

bull Standardized Treatment Algorithm

bull Non-MD BP clinic

bull Pharmacy RN support

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 29: Hypertension Guidelines AMGA Plank 2

Effective workflows

Standardized treatment algorithm

bull Simple

ndash one BP target for all patients (lt14090) ndash DMCKDetc

bull Fewer steps ndash easier for providers and patients

ndash (1) ACEHCTZ (2) CCB (3) Aldactone or BB

bull Faster control patient satisfaction

bull Fewer pills improved patient compliance

bull Fewer visits to providers improved access for patients

bull Available on KP website from any Kaiser computer

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 30: Hypertension Guidelines AMGA Plank 2

CMI HTN Treatment Algorithm Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 31: Hypertension Guidelines AMGA Plank 2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Begin with LisinoprilHCTZ

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 32: Hypertension Guidelines AMGA Plank 2

SBP Reduction Monotherapy ACEI Vs Combination therapy with HCTZ

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 33: Hypertension Guidelines AMGA Plank 2

14 of ACEI Rxrsquos dispensed

as Single Pill Combination Therapy

0

10

20

30

40

50

60

70

80

90

100

2001 2002 2003 2004 2005 2006 2007 2008 2009

O

f A

ll A

CE

I R

xs

ACEI OnlyTablet

ACEI + HCTZTablet

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 34: Hypertension Guidelines AMGA Plank 2

LisinoprilHCTZ and Hypertension

Performance

Prinzide Rate vs HTN Performance

37373633

3027

18

85858380

7371

64818078

74

6865

0

10

20

30

40

50

60

70

80

90

100

2005 2006 2007 2008 2009 2010 2011

PRINZIDE RATIO CSG POINT

LisinoprilHCTZ Rate vs HTN Permormance

LisinoprilHCTZ Ratio

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 35: Hypertension Guidelines AMGA Plank 2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Beta-Blocker OR Spironolactone

Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

OR IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ (Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Amlodipine is Third Drug

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 36: Hypertension Guidelines AMGA Plank 2

Management of

Adult Hypertension1

1

If ACEI intolerant or pregnancy potential

Calcium Channel Blocker

Add amlodipine 5 mg X frac12 daily 5 mg X 1 daily 10 mg daily

Spironolactone or Beta-Blocker

IF on thiazide AND eGFR ge 60 mlmin AND K lt 45 Add spironolactone 125 mg daily 25 mg daily

OR Add atenolol 25 mg daily 50 mg daily (Keep heart rate gt 55)

If not in control

If not in control

If not in control

Thiazide Diuretic

Chlorthalidone 125 mg 25 mg

OR HCTZ 25 mg 50 mg

If not in control

ACE-Inhibitor2 Thiazide Diuretic

Lisinopril HCTZ

(Advance as needed) 20 25 mg X frac12 daily 20 25 mg X 1 daily 20 25 mg X 2 daily

Pregnancy Potential Avoid ACE-Inhibitors2

Spironolactone Preferred Fourth Drug

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 37: Hypertension Guidelines AMGA Plank 2

37

Year 2001 2003 2005 2007 2009

Step 1

TD or BB TD TD or TD + ACEI

TD or TD + ACEI

TD or TD + ACEI

Step 2

TD + BB TD + ACEI or TD + BB

TD + ACEI TD + ACEI TD + ACEI

Step 3

TD + BB + ACEI

TD + BB + ACEI

TD + ACEI + BB

TD + ACEI + BB

TD + ACEI + DCCB

Step 4

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + BB + ACEI + DCCB

TD + ACEI + DCCB + BB or Spir

TD=Thiazide Diuretic BB=Beta Blocker ACEI=Angiotensin Converting

Enzyme Inhibitor DCCB=Dihydropyridine Calcium Channel Blocker

Spir=Spironolactone 1995-2001 No Significant changes after step 2

BB not 1st

ACEI or BB 2nd

SPC OK 1st

ACEI 2nd

BB 3rd DCCB 3nd

BB OK 4th BB OK 1st BB OK 2nd BB 3rd BB still 3rd

BB OK 4th

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 38: Hypertension Guidelines AMGA Plank 2

Non-MD Blood Pressure Check

Blood Pressure Clinic

bull ANY BP measured in ANY primary care or specialty setting is

captured and an appointment is made in BP clinic

ndash BP measurement is rechecked manually after 5 minutes

on any elevated reading

ndash Captures patients in Optometry OB-GYN Podiatry Derm

Many of these patients may not see PCP regularly

bull Non-physician based clinic (BP check with medical assistant)

ndash Patient seen same-day in center if BPgt 13989

ndash PCP adjusts therapy before patient leaves

ndash Repeat appointment every 2 weeks until BP controlled

ndash No charge Walk-ins welcome removed all barriers for

patients

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 39: Hypertension Guidelines AMGA Plank 2

Reliability Proactive Care

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 40: Hypertension Guidelines AMGA Plank 2

BP at goal

Doctor clinic visit

BP over goal

Follow up

non-MD visit

Treatment

intensification

BP check

Advantages

No charge for visit

Shorter visit for patient

Scheduling flexibility

Improves access to MD

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Non-MD Blood Pressure Check

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 41: Hypertension Guidelines AMGA Plank 2

Hypertension Control Rates 2001-2009

KP Northern California

40

45

50

55

60

65

70

75

80

85

2001 2002 2003 2004 2005 2006 2007 2008 2009

C

on

tro

lled

Year

Commercial Rate as

reported to HEDIS

44

80

Marc Jaffe MD bull The Permanente

Medical Group Inc bull 3252013

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 42: Hypertension Guidelines AMGA Plank 2

Hypertension Control Rates 2006-2011

KP Mid-Atlantic States

60

65

70

75

80

85

2006 2007 2008 2009 2010 2011

Perc

en

tag

e

Measurement Year

CA BP clinic 65

83

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 43: Hypertension Guidelines AMGA Plank 2

Hypertension Control ndash Ethnicity

KP Mid-Atlantic States

Only 28 difference in

BP control between

white and black patients

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 44: Hypertension Guidelines AMGA Plank 2

KP Blood pressure Control

Kaiser Northern California

bull 33 million members 5000 physicians 17 medical centers

bull 2001 to 2009 HTN control nearly doubled from 44 to 80

359000 more people had controlled HTN

Kaiser Mid-Atlantic States

bull 500000 members over 900 physicians

bull 2010 ndash HTN was made a top priority

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 45: Hypertension Guidelines AMGA Plank 2

HEDIS 2012

Top Ten Performance - MEDICARE

Plan State Contract Plan Type

Rate

State

Rank

National

Rank

Kaiser Foundation Health Plan of Ohio OH H6360 HMO 8881 1 1

Kaiser Foundation Health Plan of Colorado CO H0630 HMO 8833 1 2

Kaiser Foundation Health Plan Inc - Southern California CA H0524 HMO 8832 1 3

Kaiser Foundation Health Plan Inc - Hawaii HI H1230 HMO 8783 1 4

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA H2150 HMO 8597 1 5

Gundersen Lutheran Health Plan Inc WI H5262 HMO 8516 6

Kaiser Foundation Health Plan Inc - Northern California CA H0524 HMO 8402 2 7

Group Health Plan Inc MN H2462 HMO 8308 8

Kaiser Foundation Health Plan Inc - Northern California CA H6052+ HMO 8297 3 9

Chinese Community Health Plan CA H0571 HMO 8247 10

HealthAmerica Pennsylvania Inc PA H3959 HMO 8081 11

Kaiser Foundation Health Plan of the Northwest Inc ORWA H9003 HMO 8029 1 12

Partnership Health Plan Inc WI H5206 HMO 7951 13

ConnectiCare Inc CT H3528 HMO 7944 14

HealthPartners MN H2422 HMO 7939 15

HealthSun Health Plans Inc FL H5431 HMO 7908 16

Horizon Blue Cross Blue Shield of New Jersey Inc NJ H3154 HMOPOS 7844 17

Medical Associates Health Plan Inc IL HMO 7810 18

Tufts Associated Health Maintenance Organization Inc MA H2256 HMO 7764 19

Humana Wisconsin Health Organization Insurance Corporation WI H6622 HMOPOS 7762 20

Kaiser Foundation Health Plan of Georgia Inc GA H1170 HMO 7508 1 33

Total Number of Reporting Plans (excluding PPOs) 261

+Closed contract

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 46: Hypertension Guidelines AMGA Plank 2

HEDIS 2012

Top Ten Performance - COMMERCIAL

Plan State Plan Type

Rate

State

Rank

National

Rank

Coventry Health Care of Illinois Inc IL HMOPOS 8885 1

Cigna HealthCare Mid-Atlantic Inc DCMDVA HMOPOS 8750 2

Kaiser Foundation Health Plan Inc - Northern California CA HMO 8708 1 3

Kaiser Foundation Health Plan Inc - Southern California CA HMO 8564 2 4

Kaiser Foundation Health Plan Inc - Hawaii HI HMO 8443 1 5

Kaiser Foundation Health Plan of the Mid-Atlantic States Inc DCMDVA HMO 8304 2 6

Kaiser Foundation Health Plan of Ohio OH HMO 8273 1 7

HealthPartners Inc MN HMOPOSPPO 8007 8

Gundersen Lutheran Health Plan Inc WI HMO 7908 9^

Wellmark Health Plan of Iowa Inc IA HMOPOS 7908 9^

Medical Associates Health Plan Inc IA HMOPOS 7859 11

ConnectiCare Inc CT HMOPOS 7836 12

Geisinger Health Plan PA HMOPOS 7719 13^

Tufts Associated Health Maintenance Organization Inc MA HMOPOS 7719 13^

HealthAmerica Pennsylvania Inc PA HMOPOS 7692 15

Kaiser Foundation Health Plan of Colorado CO HMO 7686 1 16

Kaiser Foundation Health Plan of the Northwest Inc ORWA HMO 7664 1 17

Group Health Cooperative of Eau Claire WI HMO 7655 18

Saint Marys HealthFirst NV HMOPOS 7616 19

Security Health Plan of Wisconsin Inc WI HMOPOS 7591 20

Kaiser Foundation Health Plan of Georgia Inc GA HMO 6237 2 134

Kaiser Foundation Health Plan of Georgia Inc GA POS 4161 6 181

Total Number of Reporting Plans (excluding PPOs) 183

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 47: Hypertension Guidelines AMGA Plank 2

KP Keys to Achieving BP control

Take Home Points

bull BP checks (and mgmt) at every patient care encounter

ndash Including optometry OB-GYN etc

bull BP clinic (Non-MD clinic)

ndash Free and frequent visits walk ins welcome

ndash Removing all barriers for patients

bull Simple algorithm ndash easy for providers and patients

ndash One BP goal (lt14090) for all patients

ndash Emphasis on combination pills (lisinopril HCTZ)

ndash Emphasis on getting to target BP control quickly

bull Feedback on Performance Transparency

ndash Panel management electronic tools

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 48: Hypertension Guidelines AMGA Plank 2

Acknowledgements

Bernadette Loftus MD

Robbie Pearl MD

Michael Dias MD

Doug Vanzoeren MD

Joel Handler MD KPNC

Mark Jaffe MD KPNC

Karin Dodge MD

Joe Territo MD

Judy Dejarnette MD

John Golden MD

Carol Cardinale MD

Loan Nguyen MD

Kathryn Brown

Carol Foster MD

Susan Fiorella MD

Joyce Jones

Jerry Penso MD

Stacey Shapiro

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 49: Hypertension Guidelines AMGA Plank 2

Clinical References

AMGA Best Practices in Hypertension

Controlling Blood Pressure Kaiser Mid-Atlantic 2006

httpwwwamgaorgresearchresearchHypertensionCompendiumskaiserpdf

Hypertension Best Practices Kaiser Mid-Atlantic 2010

httpwwwamgaorgresearchresearchHypertensionSymposiumkaiserpdf

CDC

httpwwwcdcgovbloodpressure

httpwwwcdcgovdhdspdata_statisticsfact_sheetsfs_bloodpressurehtm

NHLBI

httpwwwnhlbinihgovhealthprofheartindexhtmhbp

httpwwwnhlbinihgovhealthprofhearthbpsalt_updpdf

AHA

httpwwwheartorgHEARTORG

httpwwwheartorgHEARTORGGeneralHeart-and-Stroke-Association-

Statistics_UCM_319064_SubHomePagejsp

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 50: Hypertension Guidelines AMGA Plank 2

Clinical References

NICE guidelines National Institute of Clinical Excellence (Britain)

httpwwwniceorgukguidanceCG127

httpwwwniceorguknicemedialive135615601556015pdf

ACCF AHA Guidelines

httpcircahajournalsorgcontent123212434long

ADA 2013 Guidelines

httpwwwndeiorgdslnewslideaspxSlideid=2990

American Diabetes Association Standards of medical care in diabetesmdash2013 Diabetes Care

201336(suppl 1)S11-S66

European Society of Hypertension

Mancia G Laurent S Agabiti-Rosei E et al European Society of Hypertension Reappraisal of European

guidelines on hypertension management a European Society of Hypertension Task Force document J

Hypertens 27(11) 2121ndash2158(2009)

European Society of Cardiology (ESC)

httpwwwescardioorgguidelines-surveysesc-

guidelinesGuidelinesDocumentsEssential_Messages_CVD_Preventionpdf

httpwwwescardioorgguidelines-surveysesc-guidelinesPagescvd-preventionaspx

Detailed list of international guidelines

httpbestpracticebmjcombest-practicemonograph26treatmentguidelineshtml

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts

Page 51: Hypertension Guidelines AMGA Plank 2

Clinical References

Smith SC Collins A Ferrari R et al Our Time A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke) J Am Coll Cardiol 201260(22)2343-2348 doi101016jjacc201208962

Go AS et al Heart Disease and Stroke statistics ndash 2013 update a report from the AHA Circulation 2013

Garg JP et al Am J Hypertens 2005 May18(5 Pt 1)619-26 Resistant hypertension revisited a comparison of two university-based cohorts