i journal d cerebral circulation -...
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i Journal d Cerebral Circulation
MEDICAL LIBRARYVA CENTER
Wilmington, Delaware
zJln Official iJburnalofthe^
(^American Heart"a/lssociation, Inc.
VOLUME 10 NUMBER 6
NOVEMBER-DECEMBER 1979
(Volume Index In This Issue)
lschemic Cerebral Edema. A Review 623M D O'Brien
Prostaglandin I2 and Idomethacin Prevent Im-pairment of Post-lschemic Brain Reperfusionin the Dog 629
John M. Hallenbeck and Thomas W. Furlow, Jr.Prevention of Experimental Subarachnoid Hem-
orrhage-Induced Intracranial Arterial Vaso-necrosis with Phosphodiesterase InhibitorPhthalazinol(EG-626) 638
John F. Alksne and P. Josephine BransonAttenuation of lschemic Brain Edema by Pento-
barbital after Carotid Ligation in the Gerbil 644Pablo Lawner, John Laurent, Frederick Simeone,
Eugene Fink, and Elliot RubinBarbiturates in Focal Ischemia of Primate Cor-
tex: Effects on Blood Flow Distribution,Evoked Potential and Extracellular Potassium 647
Neil M. Brans ton. Terence Hope, andLindsay Symon
Influence of Various Agents on the Developmentof Brain Edema in the Rat Following Micro-embolism. Protective Effect of Gamma-Butyrolactone 653
Jean Bralet. Paulette Beley, Anne-Marie Bralel,end Alain Beley •»
Changing Pattern of Cerebral Infarction: 1945-1974 657
W. Michael Garraway, Jack P Whisnant,Leonard T. Kurland, and W. Michael O'Fallon
Recovery in Treated Aphasia in the First YearPost-Stroke 663
Martha Taylor Sarno and Eric LevitaMassive Doses of Steroids in Cryogenic Cerebral
Injury and Edema 670Raymond A. Clasen. Sylvia Pandolfi,
and Jaclynn R. ClasenHistopathological Reactivity of Carotid Arteries
of Normotensive Sprague-Dawley vs Spon-taneously Hypertensive Rats to LigationInjury 674
Bernard C. Wexler
Intracranial Venous Thrombosis in YoungWomen 680
Bruno Estanol. Alejo Rodriguez, Guillermo Come,Jose Manuel Aleman, Mauro Loyo,and Javier Pizzuto
Levels in Stroke Patients of CFS Astroprotein,and Astrocyte-Specific Cerebroprotein 685
Toru Hayakawa. Yukitaka Ushio, Takesada Mori,Norio Arila, Toshiki Yoshimine,Yasulaka Maeda, Keiji Shimizu, andAkio Myoga
Measurement of Regional Brain Glucose Utiliza-tion In Vivo Using [2-MC] Glucose 690
Richard Hawkins, William K. Hass,and Joseph Ransohoff
Experimental Cerebral Vasospasm after Sub-arachnoid Hemorrhage. Participation ofAdrenergic Nerves in Cerebral Vessel Wall 703
Shunro Endo andjiro SuzukiEffects of Hemorrhagic Hypotension on the Cere-
bral Circulation. I. Cerebral Blood Flowand Pial Arteriolar Caliber 711
Eric T. MacKenzie, J. Keith Farrar,William Fitch, David I. Graham,Peter C. Gregory, and A. Murray Harper
Effects of Hemorrhagic Hypotension on theCerebral Circulation. II. ElectrocorticalFunction 719
Peter C. Gregory, Anne P. McGeorge,William Fitch, David I. Graham,Eric T. MacKenzie, and A. Murray Harper
Effects of Hemorrhagic Hypotension on theCerebral Circulation III. Neuropathology 724
David I. Graham, William Fitch,Eric T. MacKenzie. and A. Murray Harper
Correlated Electrical and Mechanical Responsesof Isolated Rabbit Pial Arteries to SomeVasoactive Drugs 727
N.A.T. Lusamvuku. R. Sercombe. P. Aubineau,and J. Seylaz
continued on back cover
SJCCA 10(11-12)623-761(1979)ISSN 0039 2499
Publication number is 878740
Effect of Phenobarbital on Cerebral Energy Stateand Metabolism. Enzymatic Activities . . . 733
G. Benzi, A. Agnoli. F. Dagani, S. Ruggieri.and R.F. Villa
Pharmacological Comparison of Isolated HumanCerebral and Digital Arteries 736
Gary A. Rose and Robert F. W. Moulds
Abstracts of Literature
Erratum 741
An Appreciation 742
LETTERS TO THE EDITOR: Death in EarlyStroke, Causes and Mechanisms 743
O. B White. J W. Korris. V. C. Hachinskiand A. Lewis
744
News from American Heart Association 762A
Volume Author Index 767
Volume Subject Index 770
UltrasonicStroke Screening
SystemDOPSCAN™ is an ultrasonic, Doppler, arterial scanningsystem for early detection of potential stroke conditions.
It provides a noninvasive evaluation of the carotidbifurcation and other peripheral arteries to indicate thelocation and severity of arterial insufficiency andplaquing. It is a valuable supplement to X-ray angiography.
The simplicity and safety permit a physician toeasily follow the process of plaquing or a patient'sprogress after arterial surgery.
The DOPSCAN™ system is unique in that it providesa set of permanent exam records consisting of:(1) Mapped image of the carotid bifurcation, (2) Stripchart recordings showing pulsatile velocity waveformsin forward or reverse flow, and (3) Magnetic taperecordings of the customary Doppler flow sounds,which present the flow information in aural form alongwith the operator's commentary.
FIFTHINTERNATIONALJOINT CONFERENGO N STROKE ANDCEREBRALCIRCULATIONFebruary 21-23 1980Dutch Inn Resort Hotel, Walt Disney World, Lake Buena Vista, Flori
The Stroke Council of theAmerican Heart Associationin association with the Cere-brovascular Surgery Sectionof the American Associationof Neurological Surgeons,The Canadian Stroke Societyof The Canadian Heart Foun-dation and The Society forVascular Surgery is pleasedto announce the 5th Interna-tional Joint Conference onStroke and Cerebral Circula-tion.
This is an open meeting,whose purpose is to providea common forum for the pre-sentation of material relatingto all aspects of cerebrovas-cular disease and the physi-ology and pathology of thecerebral circulation. Ab-stracts dealing with the clini-cal or experimental aspectsof the pathogenesis, diagno-sis, medical and surgicalmanagement of vascular dis-ease of the brain and spinalcord are welcome.
Physicians and investigatorsinterested in diseases of thecerebral circulation and thephysiology and pathologicalchanges in the cerebral cir-culation are encouraged tosubmit abstracts to the Pro-gram Committee for consid-eration to be presented atthat meeting. Abstracts ac-cepted for presentation willbe published in the January1980 issue of the journalStroke of the American HeartAssociation.
Guidelines and furthermotion may be obtainswriting: Administrator, Pgraduate Programs, Ancan Heart Association,Greenville Avenue, DallTexas 75231. Phone (2 V750-5441. Robert G. SielM.D. of the Mayo Clinicand J. Donald Easton, tof the University of Misscare serving as ConfererCo-Chairmen.
Hotel reservation cards will be mailedwith a letter confirming registration
American HeartAssociation