IAPCOI perspectives on Rotavirus vaccines: What are the issues?

Vipin M. Vashishtha, MD, FIAPConvener, IAPCOI 2011-13

vipinipsita@gmail.com

• Do we have significant disease burden to warrant universal immunization ag rotavirus?

• Are the available vaccines potent enough to provide adequate protection?

•

Efficacy of RV vaccines in India

• OPV fared poorly only in India!!!

• What ought to be the schedule of using RV in India?

• Do we need to adopt 3-dose series of all RV vaccines?

• Do we need to use these vaccines differently to get most out of them?

• What about catch-up schedule?

• How effectively current RV vaccine going to provide homotypic & heterotypic protection?

• Whether vaccination may lead to the replacement of vaccine-type strains??

• What about the risks of intussusceptions ?

• Are the current vaccines indeed cost-effective?

• What is the status of Indian RV vaccine? • Should we wait till the results of Rotvac TM

are available?