ibc brochure

8/12/2019 Ibc Brochure

1/3111-800-701-7345


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Rodrigo Rodriguez MD ,medical director and cofound-er of International Bio Care

Hospital and Medical Center, is aninternationally acclaimed and widelyrespected physician with a succesfulacademic career, and many researchpapers, symposia and conferencesin his curriculum. He decided a quar-ter century ago to enter the eld ofnutritional, immune and integrativetherapies. With postgraduate studiesin the US, Canada and Germany hehas researched, implemented andpioneered modalities that are now

becoming standard therapies. He isone of the most recognized expertsin the integrative medicine world andhas devoted his time and experienceto bringing together advanced andhigh-tech medical achievements.

Our TreatmentPhilosophy

IBC Hospitals general treatment approachis based on these concepts:

1. The uniquely individual biochemistry of the patient.

2. The development of treatment programs (protocols) takingthis unique individualized biochemistry into account.

3. A multifactorial, integrative, succesive, restorative approach aiming at:

Detoxication and dietary adjustment. Balancing of the neuro-endocrinological (hormonal) systems. Regulation and restoration of the various components of the immune defense

system. An all-out attack on pathogens with the fullest possible range of modalities with

an emphasis on natural, non-toxic methods. Exhaustive review of dental health to ensure the absence of infectious foci and

the presence of mercury amalgams and other potentially toxic materials. Fostering of a healing psychological milieu.

IBC Hospital is aware that no two patients are exactly alike, so that no two treaments (in application or response) are exactly alike. We are interested not in treating

disease persebut in helping our patient heal him/herself.

Integrative diagnostics and clinical applications are bringing about long-term survivals andmany cases of complete success in advanced disease conditions around the world.

IBC Hospital is the home of many breakthrough therapies that were researched andeveloped to safe and effective levels never before achieved.

The IBC staff notes that its maximum effort is aimed at restoring wellness and controlinmost of the metabolic conditions we have treated in thousands of patients from sometwo dozen countries over a quarter century.

With a professional bilingual staff at all levels, from medical to nursing, from administrative to transportation, we all strive to create a caring and nurturing environment for thpatient. IBC Hospital has accumulated for over 25 years the experience and know-howto implement and successfully manage one of the major integrative health centers inthe world.

We emphatically believe thatmedical intervention should

be comprehensive andintegrative that one part isnot more important than theother and some therapies

should be implemented onlyafter certain goals have

been reached.

The

Bio Care System


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International Bio Care Hos-pital and Medical Centerwithmore than a quarter-century of dedi-cated experience in the eld fullls

your quest for a total treatment centerin which all forms of state-of-the-arttherapies integrative medicine,with a strong bias toward natural

treatments are available for themanagement of a full range of dis-eases, chronic metabolic disorders,immunological conditions and geneticchallenges.

Years of professional experi-ence have thrust International BioCare Hospital into world prominenceas a leader in the development andapplication of individualized, integrat-ed (custom-made) programs in themanagement of all forms of disease

and pathological conditions.

Long-term survivors fromaround the world have helped bringrenown to our veteran, licensed, bilin-gual medical staff, our support teamof research scientists and physiciansfrom around the world.

The caring environment of ev-eryone connected with InternationalBio Care Hospital from drivers tokitchen personnel to nurses and our14-member medical staff and ourtrack record of long-term recoveriesmake our fully accredited facility yournatural choice for a healing and treat-

ment center.

The International Bio-Care Systemis a full package of health-orientedservices that focus on the individualstotal well-being embracing the bestin hospitalized care, state-of-the-artdiagnostics and monitoring, preven-tive health maintenance and a fullline of metabolic pharmaceuticals,

supplements and health products.

International Bio Care Hospitaland Medical Center offers:

Full in-house hospital services,including room and board, intensivecare unit, nurses station and tele-phone communication, cable colortelevision, personalized in-roomnursing when necessary. Organic kitchen and dining roomwhich prepares meals both for in-house patients and outpatients aswell as visitors and loved ones.

Our Medical Nutrition Departmentdirector is continually adding newdietary approaches to our alreadyhighly respected dining services.

On-site laboratories for utilizationof state-of-the-art diagnostics includ-ing high resolution digital medicalmicroscopy. Augusti test (reticuloendothelialprole), a 9-parameter immunologi-cal performance test. The Augustitest has become a major monitor ofcancer activity and immune perfor-mance, offered exclusively by Inter-national Bio Care Hospital. Outpatient services for the lessseriously challenged, including acomfortable and fully staffed generaltreatment area. VIP suites for outpatients andfamilies in spacious accommodationsattached to the medical center. In-house television channel forpatient orientation on therapies andtreatments and for special videoevents. Fully equipped operating room. Individual consultation ofces formedical staff. Transportation to and from SanDiego International Airport and fromhotels and motels. Laundry, exercise, mail and secu-rity services. Full dental and other medicalspecialties available.. On-site X-ray and ultrasound di-agnostics.

IBC Hospital and Medical CenterYour best option in integrative healthcare

International Bio Care Hospitamaintains around-the-clock medicaand nursing services, chauffeur avaiability during working hours every daand has a full complement of kitcheand maintenance personnel trainedto cater to patient needs. Our modern facilities are located only twentminutes from San Diego InternationaAirport.

Our modern, semiprivaterooms are equipped with telephonecolor television with US channels

an in-house, closed-circuit television channel for patient educatioprograms, intercom and private

bathroom. A security safe, securecomputer port with high-speed internet connection in every room, maiinternational telephone and FAXservices are available as well as anInternet access kiosk for browsingand e-mail needs.


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NUTRITIONAL MEDICINE.IBC Hos-

pital remains at the forefront in offering

dietary support and the proper balanceof oral/intravenous administration of vi-

tamins, minerals, enzymes, amino acids,essential fatty acids, herbal extracts and

other nutrients to achieve balanced body

chemistry (homeostasis) and as immunesystem modulators. Germanium, sele-

nium, and coenzyme Q10 are amongmany broad-spectrum nutrients in usein addition to mega-vitamins, minerals,

enzymes and herbs.

DETOXIFICATION/COLON THERAPY.

Recognizing the extreme importance ofsound gastrointestinal tract function, IBC

Hospital applies numerous detoxication

techniques including fasting, enemas,and human ora replacement therapy

as an integral part of metabolic treat-

ments.

COMPREHENSIVE ANTIOXIDANTTHERAPIESThe balancing, supple-menting, and enhancing of antioxidants,

which selectively destroy or inhibittoxic oxygen factors (free radicals),

has been a major IBC Hospital research

endeavor.

LIVE CELL THERAPY. IBC Hospital

is the major center where continuingresearch, development and application

of fresh cell therapy techniques (sub-

dermal or intramuscular suspensionsof birth related animal tissues) as pio-

neered early in the 20th century by thelate Paul Niehans MD of Switzerland are

in place for regeneration, rejuvenation

and endocrine balancing.

LAETRILE THERAPY. IBC Hospital

has researched and applied amygdalin

(laetrile, vitamin B17), both intravenouslyand orally, as important anticancer

agents.

EDTA CHELATION TREATMENTS.

EDTA, mans miracle molecule, is ad-ministered intravenously and by supposi-

tory for the chelation (clawing out) of

toxic heavy metals and minerals as partof a program of detoxication, improved

circulation, immune enhancement, and

the inhibition of free radicals.

CHONDROITIN SULFATES.Revolutionary techniques to improve

blood ow, treat arteriosclerosis, and

help prevent heart disease include thesesubstances.

ACUPUNCTURE & ACUPRESSURE.Dr. Richard Park, in charge of acu -

puncture/acupressure therapies also

provides metabolic breathing exercisesto enhance the function of acupuncture/

acupressure while also oxigenating theblood. These techniques are useful in

pain control, diagnostics, immune en-

hancement, and endocrine balancing.

BIOELECTRICAL REPOLARIZATION

of tumors based on Dr. Nordenstroms

research in Sweden is a major modalityresearched by IBC Hospital staff.

INTEGRATED STANDARD

TREATMENTS.Standard medical pro-

cedures and substances are integratedinto total integrative programs with heavy

metabolic support for individual andspecial needs.

SPECIALIZED THERAPIES.

Specialized state-of-the-art programs,developed from high technology re-

search centers, all from our globalresearch connections, are available as

newer modalities in immune-building,

anti-malignant or homeostasis-manag-ing activity.

AUTOLOGOUS DENDRITIC CELL

VACCINES, An exciting new experi-

mental therapy, vaccines made from

a patients own tumor cells and "den-dritic" immune cells are customized and

administered to the patient as "smartbombs" which entrap and destroy ma-

lignancies.

This novel high-tech approach is non-toxic and provides an entirely new

dimension to cancer therapy. (see also

Integrative Medicine for the Treatmentof Cancer.)

WHOLE-BODY HYPERTHERMIA,

which consists of the elevation of the

core temperature of the body achievedby circulating the blood through a high-

tech heat-exchange device, has provid-

ed positive results in advanced cancer.(see special section)

ULTRAVIOLET BLOOD IRRADIATION

THERAPY (U.B.I.T.), also known as pho

toluminescence, photo-oxidation, anextracorporeal photophoresis, in whic

UV treatment of blood helps improvmicrocirculation and oxygenation of tis

sues, stimulates the immune system

and has powerful antiviral, antibacteriaand antiinammatory properties. It ca

also reduce the size and inammatoractivity of large tumors. (see speciasection)

ADVANCED OXIDATIVE THERAPIESOzone and advanced oxidative agents

hyperbaric oxygen, and oxygen-releas

ing molecules are some of the mosadvanced oxidative agents for nontoxi

antiviral, antibacterial and antifunga

management. IBC has its own hyperbaric oxygen chamber. It is also the

major center for the administration o

concentrated atomic oxygen in theform of BiOx, which is a major oxidativ

therapy available intravenously and asublingual drops.

We are integrating all

of progressive med

standard and integrain the management o

generative diseas

International Bio Care Hospital through its yearsof experience with research associations and

institutions around the world has made avail-

able one of the most comprehensive integrativetherapy programs.

IBC Hospital understands the uniqueness of eachpatient at different stages and has found that

successive, individualized, integrative, restorative

protocols are the way to success.


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There are 8 full-time and part-time

physicians on staff and a support team

of hundreds of consultants from Mexicoand the United States. Nonresident

physicians from around the world havehospital privileges at IBC Hospital.

IBC Hospital has a licensed and reg-istered nursing staff for its inpatient and

outpatient facilities and sixty supportpersonnel. The hospital maintains ongo-ing orientation videotapes and a bureau

of speakers who present instructional

programs.

Special programs for rejuvenation, im-mune system enhancement, longevity

and promotive health are available at

IBC Hospital and Medical Center.

With the theme adding years to your

life and life to your years, IBC pio-neered live cell therapy-based programs

in which hormone balancing through the

use of extracts of birth-related animalendocrine tissues is the centerpiece of

a total program including:

Laboratory workup with advanced

blood, urine and stool proles, as wellas food sensitivity and immunological

panels.

Intravenous feed-

ing and oral nutritional

programs with a strongemphasis on antioxi-

dants, which offer totalsupport and restora-

tion to the seriously

challenged patient.

Specic anti-agingcompounds such asGerovital (GH3) and longevity-inducing

medications, including human growth

hormone, Regeneresen, ginseng, ginkgobiloba. All can be integrated into easily

complied-with, highly successful therapy.

EDTA chelation therapy, which not

only helps protect the circulatory systemfrom plaque buildup and detoxies the

body of minerals and metals, but also

properly balances calcium and enhanceslive cell injections.

Cosmetic and/or restorative surgerywhere necessary or desired.

Accommodations for patients seeking

rejuvenation/longevity programs are

available at the VIP suites attached tothe hospital or at comfortable hotels and

motels on both sides of the border.

The IBC staff encourages the public to

take advantage of existing diagnostic

and treatment modalities now so thatpromotive health can become a reality

for the many instead of the few.

For the past quarter-century,

International Bio-Care Hospital andMedical Center has been facing the ever-

present question of whether to embarkon so-called alternative or integrative

therapies or follow mainstream, conven-

tional or orthodox therapies.

In conventional oncology the

concept of making the body less toxic,improving diet and nutrition and regulat-

ing the immune system while treating

the malignancy is still widely regarded

as an unimportant aspect of medicalcare.

The belief that medication alone

can and should reverse disease andcure a patient without any consideration

of the bodys own defense and recovery

systems still dominates the medicalmentality.

In standard oncology, there i

no treatment which is not deleterious t

the immune system or the overall hosdefense of the patient. In our concep

the foundation of any form of therapyshould be the restoration of the biolog

cal capacities of the host with specic

emphasis on the immune system. Supported by the recovery of the patient

own defense mechanisms medicaintervention in the form of specitherapies can then take place. Such

an approach in due time hopefull

will lead the patient to a better quaity of life and improved longevity.

This is the concept of Integrativ

Medicine. We emphatically believe

that medical intervention should bcomprehensive and successive

one part is not more importan

that the other and some therapieshould be implemented only afte

certain goals have been reached

For example, to give chemo

therapy to a patient who recentlunderwent surgery will only worsen hi

appetite, strength and wellbeing, reduc

ing defense systems and the chances osuccessful outcome.

In standard radiotherapy programs, statistics show that the higher the

dose of radiation, the higher the tumora

response. However, the same statisticprove that higher doses mean less sur

vival. This means that we must strike abalance between how aggressively we

attack the tumor and how much sup

port we give the body or at least howmuch assault our biological systems ca

endure.

INTEGRATIVE MEDICINE FOR THE

TREATMENT OF CANCERby Rodrigo Rodriguez MD, Medical Directo

International Bio Careuses only the nestproducts available,

looking always for quality,performance recordand natural sources.

Only the best productswill be used and prescribed

by our doctors.

Creating a Health Team with patientand doctors alike, careful planning,understanding and commitment are thefoundation of the Bio Care System


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Another important concept to

understand is that a healthy body with

an intact defense system does not de-velop cancer. So the mere fact of cancer

presence denotes a failure, mutation, orbiological change important enough to

trigger such a diagnosis.

If we continue to follow the con-

cept that the elimination of the tumormass brings cure, we will continue tosee the recurrence of cancer which is

one of the consistent outcomes of con-

ventional oncology. The fact is that whena breast tumor, for example, is removed

we are far from solving the problem. Sothe lump is not the disease and that

should be the conclusion.

In an integrative model we follow

four major principles: restoring the best

possible biological conditions throughnutrition, rest and exercise; detoxifying

the body; regulating the immune system;

and using a wide array of modalities, al-ternative and conventional alike, against

the malignant process itself.

We stress the concept of bio-

chemical individuality - no two patientsare treated identically. Since each

patient is different and each patients

response to cancer let alone its therapyis also different, we individualize our

therapies.

The concept of biological indi-

viduality is easy to grasp since we haveindividual genetic pools that are not iden-

tical other than in identical twins, and we

are raised under different circumstances,climates, diets, etc. We are exposed

to different immunological challenges

throughout our lives with unique biologi-

cal experiences.

We are exposed

to different pol-lutants and tox-

ins. Finally, ourindividual mental attitudes give stress a

personal touch that impacts on each and

every one of us.

Much attention in recent yearshas focused on dietary considerationsin chronic disease yet, just as there

is no one-treatment-ts-all therapeutic

approach to cancer, neither is thereone-diet-ts-all, and we must be as at -

tentive to individuality in diet as we areto individuality in therapy.

In critical cancer patients, inten-sive crisis nutrition can only be attained

by intravenous feeding that will deliver

to the blood all the critically necessarynutritional elements in an immediate and

efcient way. It is easy to understand that

patients with cancer are malnourished bylack of appetite, depression and medical

interventions such as surgery, chemo-therapy and poor digestion.

The mere satisfaction of nutri-tional needs represents a major step

toward well-being and the recovery of

biological capacities.

This is a concept well supported

by research at major medical schools.Intravenous nutrition rapidly improves

white blood cell (WBC) performance al-lowing restoration and enhanced activity

of a key element in ghting cancer: cel-

lular immune performance.

Supplementation by mouth is

also a common method of managing

less critical cases.

Detoxication is a major tool if thebody is to be able to function properly.

Each function of the body is regulated by

our genetic information system throughspecic enzymes. A toxin is dened as a

substance that impairs or blocks enzymeperformance.

It is imperative to rid as many

foreign and toxic substances from thesystem as possible, a problem of enor-

mous signicance in cancer.

To detoxify the body we use,

among other things, specialized diets,juice fastin g, coffee enemas, chelat -

ing agents, replacement of friendly

bacteria and any other approach orsubstance required. Coffee enemas,

often regarded as controversial yet of

comparatively ancient pedigree even inWestern medicine, help render the small

intestine alkaline, detoxify the liver andhelp restore bowel regularity.

Of no less importance is thecareful exploration of the body to look

for sources of toxic debris, organic or

inorganic. Infectious focci, dental healthand removal of mercury amalgams are

all of primary importance.

Toxic oxygen breakdown prod-

ucts free radicals have to beneutralized or blocked, a process which

can largely be carried out with nutrients

known to have free radical-blockingthat is, antioxidant activity.

Our approach is to utilize a baseline

special blood test to measure oxidative

antioxidant activity in the blood. Antoxidant substances in general use are

SOD (superoxide dismutase), catalaseglutathione, butyrate, selenium, NAC

(N-acetyl-cysteine) and vitamins A, C

and E, Beta Carotene, to mention onlthe more prominent from a growing lis

The controversial compound laetrile isamong other things, an antioxidant.

Immune regulation involves

complex process (by some denitionthere are several immune systems

whereby internal defense mechanismare made aware of the presence of al

tered cells or tumors which are growin

wildly in the body.

Malignant processes may isolat

themselves by building a protein sheataround themselves or, as Nordenstrom

proposed, by creating an electrica

eld, making them unrecognizable tthe immune system, which otherwise

would attack them. We must overcomethis blockage by the administratio

of proteolytic enzymes as a rst-ran

weapon, or by electrical repolarizatioof the tumor.

Live cell or cellular therapy (being slowly accepted in orthodox circle

as fetal cell transplantation therapy

after being cold-shouldered for years) ia highly effective approach to long-term

immune regulation.

It consists of intramuscular o

subdermal injections of cellular suspensions of animal embryonic or other birth

related tissue. Since these kinds of sus

pensions are obtained from embryos o

Integrative MedicIntegrative MedicineWe emphatically believe thatmedical intervention shouldbe comprehensive and suc-cessive; one part is not moreimportant than the other and

some therapies should beimplemented only after certain

goals have been reached.


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other birth-related tissues in early stages

of pregnancy, they provoke no allergicresponses. The varied positive effects of

such injections have a start-up period ofseveral weeks and an endurance of up

to six months. Live cell injections have a

hormone balancing effect on the body ingeneral, a balancing effect on immunity

and some specic anticancer activity.

The direct assault on cancer

is carried out not only with such time-

tested substances as laetrile (amygdalin,

Vitamin B17), but also with a growingnumber of nutrients and herbal-derivedcompounds, combinations and extracts

which have solid research behind them.

New alkaloids are now available in com-binations that can induce the death of

cancer cells while protecting immune

cells, thus creating a brighter horizon forthe use of herb extracts in the treatment

of cancer.

These essentially nontoxic anti-

cancer compounds, together with a totalmetabolic program of dietary change,

detoxication and immune system regu-

lation, provide us with effective therapiesnot only virtually free of unpleasant side

effects but accompanied by higher en-

ergy levels, better appetite and overallimproved biological performance.

Of course, we can and do utilizesubstances from the orthodox arma-

mentarium when feasible and practical.Ongoing research has shown that a

nutritionally based metabolic program

actually enhances the effects of che-motherapy and radiation should either

of these modalities be c alled for.

Two relatively new therapies

requiring individual attention and which

have shown great promise at our hospi-tal are whole body hyperthermia and

autologous dendritic cells Results ofthese techniques have been particularly

heartening in advanced cancer cases

where the extension or severity of thecase needs intensive, more aggressive

protocols.

Whole body hyperthermia con-

sists of heating the patients body by cir-culating blood through a heat-exchange

device. This is a modern expression of

the ancient observation that cancer cellscannot stand high temperatures to which

normal cells are otherwise insensitive.

High heat sets off a cascade of intracel-lular events in cancer cells leading to

apoptosis or programmed cell death.

During this procedure the patient is se-dated in order to tolerate the increased

heat and allowed a recovery period rang-

ing from a few hours to ve days.

IBC is also pioneering the useof "autologous" meaning "made from

self" - vaccines against the cancer pro-

cess, particularly those made from therecently discovered structures called

"dendritic" cells (DCs). DC's are known

to entrap tumor cells and expose them toa patient's immune system for destruc-

tion.

By lenghtening and enhancingtumor control through human immune/

defense systems while remaining com-

pletely free of side effects over long peri-ods of use, this is the most nature-similar

way of controlling malignant growths.

It has been learned that DCs

elongated appendages in certain

cells can actually pick up normal cellsand migrate with them to Iymph nodes

where they can be exposed to a highconcentration of immune system cells.

DCs can stimulate a responsein which

the immune system increases the activ-ity of T-cells which help ght cancer and

viruses.

The procedure involves drawing

from the patient blood containing mature

and immature DCs and tumor cells. Abiochemist induces the maturation and

activation of DCs in the presence of pro-teins derived from the patient's tumor.

At this point a weapon has beencreated which administered to the pa-

tient, will act as a cellular vaccine - a

"smart bomb" - which will actively seekout, entrap and expose to the immune

system tumor cells developed at every

stage of malignancy.

The vaccine, being non-toxic,sterile and customized from the patient's

own blood, is thus a safe and effective

form of t herapy.

International research and

knowledge exchanges provide informa-tion and resources from around the world

and access to new modalities, products

and experiences that enrich and widenthe expectation of good results in the

hard battle against cancer.

Our anticancer program oslow drip infusions, direct injections

oral and sublingual nutrients, specialize

diet and detoxication normally takethree weeks, a period we call the crisi

phase.

The three-week segment is de

signed to interfere with at least one fucycle of malignant-cell replication a

process which hopefully will remove the

patient from the crisis stage.

After the initial three-week intensive-therapy phase, the patient iprovided with a program of protocol

and dietary changes to be followed a

home.

The arguments between alter

native and orthodox medicine shouldvanish with the understanding that meta

bolic illnesses are part of a multifactoriaand complex scenario.

Real medicine is unitarian - addresses the health and well being o

whole individuals. There are no such

things as different medicines or evenmedical specialties; these are man-made

concepts which help to understand how

the body works in health and disease. Inreality any attempt to treat only a part o

a patient will encounter a far less thandesired outcome.

Every effort to integrate the differing avenues of medicine, alternative

or conventional, old and new, East o

West, homeopathic or allopathic, etcwith the well-being and respect for ou

patients, needs in mind can only lead t

better, more substantial and longer-lasting results.

Integrative MedicIntegrative Medicine


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Hippocrates routinely buried

patients in the desert sand to elevate

their core body temperature in an at-tempt to cure disease. In the middle

1800s a German physician, Dr. WilliamBush, noted spontaneous remission of

sarcomatous tumors in patients who

sustained prolonged fever episodes. Dr.W. C. Colley at the turn of the century

injected cancer patients with differenttoxins to create articial fever with goodresults, and Dr. Julius Wagner-Jauregg,

an Austrian physician, was awarded the

Nobel Prize in Medicine in 1927 for hissuccessful work using malaria serum

fever induction in patients plagued withsevere complications of syphilis.

Hyperthermia represents a natu-ral approach in combating disease since

it involves inducing an exaggerated ver-

sion of the bodys own fever state.

Medical research found tha

induced hyperthermia has damagin

effects on cancerous cells and infectious agents, but the technical limitatio

in elevating body temperature in an accurate, consistent, and reproducible wa

was a major obstacle to accomplishin

this goal in humans despite the excitingresults obtained in experimental obser

vations.

Many infectious agents are

sensitive to heat particularly, but no

restricted to, human immunodeciencvirus (AIDS), Hepatitis C virus and

Lymes disease which die due to heashock before the normal human biolog

is altered.

Summarizing, we observe tha

the articial elevation of body tempera

ture either through normal physiolog(fever) or by induction (medical hyper

thermia) is an important healing factor in

the management and treatmenof several infectious processe

and in the treatment of canceMedical hyperthermia can b

applied in cases where norma

fever response is not presenbecause of the inability of th

host to react to the illness. O

key importance, medical hyperthermia is carried out unde

controlled circumstances, time

and parameters, making it safe and accurate therapeuti

tool.

Medical Hyperthermia

MEDICALHYPERTHERMIAA treatment option in the eldsof oncology and infectious diseasesby Victor Loustaunau, MD

Hyperthermia, from the Greek

words hyper,meaning high, and ther-mos,meaning temperature, can simply

be dened as the elevation of the body

temperature.

The physiological and biological

mechanisms of hot-blooded mammalsincluding humans demand that the body

maintain a temperature that is normallyabove that of the external environment.

However, it is important to note that the

same functions can only successfullyoperate within very narrow t emperature

margins.

Our bodies have developed

highly sophisticated heating and cooling

systems to maintain a stable tempera-ture within the narrow margins required

regardless of environmental conditions.The process that attempts to maintain a

steady internal thermic balance is called

homeostasis.

There are only a few physi-

ological conditions in which the thermicbalance is changed: winter hibernation,

egg-setting hens, and fever. Only fever

is a physiological thermic resource inhumans.

Fever acts as a defense mecha-

nism against a number of processes,

mostly related to either infections or thepresence of abnormal proteins in the

bloodstream called pyrogenes.

One of the most immediate physi-

ological effects of fever is the accelera-

tion of metabolic processes in general.Fever increases oxygen uptake and

renders white blood cells more aggres-sive against bacteria, fungi or viruses.

By making the cells more permeable,

white blood cells are able to dischargeinto the bloodstream more aggressive

substances against infectious organismsand increase their phagocytic (destruc-tive) capability.

Fever within physiological limitscan have many benecial effects and will

not produce any harm to normal cellsthat are able to cope with the higher

metabolic demand. Human cells under

specic metabolic conditions, such ascancer cells or infected cells, can be

seriously challenged by thermic stress

and may even be killed by it.

In summary, fever should be

seen as an important physiological de-fense mechanism against disease.

BACKGROUND INFORMATION

Because of the empirical obser-

vation that the healing process is often

preceded or accompanied by febrileepisodes, the induction of thermic eleva-

tion has been attempted as a cure for

thousands of years. In recent centuriesthere were reports of cures of cancer and

cases of syphilis, which improved spon-taneously after severe fever episodes

that were caused by other infections.


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Necrosis involves damage to the cell

by an external factor such as an injury,

infectious agent, or immune reactionand in fact is the cell death phenomenon

that we have commonly recognized andunderstood.

Apoptosis or programmed celldeath is characterized by a degradation

of the cell with shrinkage and fragmenta-tion triggered from within. Genetic mate-rial in each cell has information codes

that allow the cell to evaluate its own

functions.

Hyperthermia isone of the major

apoptosis induc-

ers. This is whyremission of can-

cer has been em-

pirically seen afterfebrile episodes

and more recent-

ly under inducedtemperature el-

evation.

The damage and

changes produced by hyperthermia canbe enhanced with the use of substances

that can further the metabolic problems

of cancer cells. Vitamin C, glucose,low-dose chemotherapy and low-dose

radiation therapy have been pointed to

as important adjuvants for a more effec-tive therapeutic outcome.

It has been proven that in pa-tients with resistance to chemotherapy,

whole body hyperthermia can reinstitut

drug efcacy. It is widely recognize

and scientically proven that whole bodhyperthermia renders cancer cells mor

sensitive to chemotherapy. This allowthe use of milder forms of chemotherap

at lower doses and hence with fewer side

effects and complications.

The same is true for radiatiotherapy: whole-body hyperthermia casubstantially increase the possible dam

age to the cancer cell with the use o

radiation. And again it is possible to usfewer radiation sessions, with shorte

times and lower doses in general, andstill obtain good results with milder side

effects.

Infectious disease: The ratio

nale for the use of whole body hyper

thermia begins with nature itself: Fever ithe most immediate reaction to infectio

and at the same time one of the bes

known and earliest recognized defensmechanisms.

Under normal circumstance

many infectious agents that were or sti

are important plagues of mankind can bdamaged and destroyed at temperature

that are easily tolerated by normal hu

man cells.

The causative agents of huma

immune deficiency syndrome virushepatitis C virus and Lymes disease

are among the most notorious infectiouagents that due to their susceptibility t

heat have become important targets o

this method.


METHODS

It wasnt until the 1970s when

Dr. Parks, a cardio thoracic surgeon,reported success in using an extra cor-

poreal technique to conduct more thanone thousand whole body hyperthermia

sessions for the treatment of cancer.

During the following two decades manyadditional studies have been conducted

and documented.

The use of external sources of

heat creates uneven heat distribution in

the body and burns are not uncommon.The extra corporeal technique involves

circulating blood through a closed circuitdevice. Extra corporeal circulation with

the help of a pump will carry the blood

through a heat exchange unit. Heat willbe transferred to the blood and then

recirculated into the body.

Utilizing the cardiovascular sys-

tem for inducing hyperthermia from the

inside out has the inherent advantageof creating an extremely uniform heat

distribution throughout the body.

During the procedure the pa-

tient, under mild sedation, is continu-ously monitored. The information from

thermometers in the body is fed back to

the computer that controls the heat ex-change unit. Because of this feedback

mechanism the core body temperature

can be consistently and reliably adjustedwith an accuracy of one tenth of a de-

gree.

In a routine treatment protocol tempera-

ture will be raised to a constant plateau

that lasts 60 to 90 minutes at a tempera-ture of 42 C (108F).

Once the procedure is termi-

nated the patient is transferred to his/her

room, monitored and assisted throughthe following hours until the next day by

specially trained nursing staff.

CRITERIA FOR ENTERING THE

HYPERTHERMIA PROGRAM

The available medical informa-tion and experience have proven that

medical Whole Body Hyperthermia hastwo major classes of patients as potential

beneciaries: cancer patients and those

with chronic progressive viral infections,mainly HIV and Hepatitis C patients.

Cancer: There are many formsof cancer in which hyperthermia can play

a major role and lead to a successful

result: Hyperthermia by itself can havelethal effects against certain forms of

cancer, and in an integrative protocolin which other nontoxic modalities are

used this method is a major adjunctive

therapy.

Cell death is a fundamental

phenomenon of organisms occurringnaturally as part of embryo development,

in cell turnover in adults and as a result

of injuries and pathological processes.There are two fundamental types of cell

death necrosis and apoptosis.


Utilizing the cardiovascularsystem for inducing hyper-

thermia from the inside outhas the inherent advantage ofcreating an extremely uniformheat distribution throughout

the body.


10/31

18

It is highly recommended that any

metabolic disturbances detected beforehyperthermia be placed under control

before this metabolism-challenging pro-

cedure is done.

Patients normally undergo in-tegrative metabolic protocols before

and after whole-body hyperthermia in

order to enhance the positive aspectsand results to be expected from such a

comprehensive program.

FINAL CONSIDERATIONS

Hyperthermia has a long history

of use in medicine in the treatment of avariety of diseases. Recently we have

seen a resurgence of its importance asa potential treatment option in the man-agement of chronic illness in the elds

of oncology and infectious diseases.


CLINICAL APPLICATION

Candidates for whole-body hy-

perthermia are carefully evaluated notonly in terms of the main diagnosis but

also their general, nutritional and overallcondition and specically their lung and

heart functions.

Careful clinical diagnosis and

staging of the disease with all possibleelements to establish the status of theillness will provide necessary informa-

tion to allow both patient and physician

to evaluate changes in the disease in anobjective and systematic manner. This

is vital in the planning of adjunctive andfuture therapies that will bring about a

successful outcome.

Radiological studies, such as CT

scans, MRI, and other X-Ray images,

are helpful elements with which to judgechanges in the progression of a tumor.

Laboratory ndings are also important

factors in this assessment, particularlytumor markers in blood.

In the case of viral infections

modern laboratory techniques can

provide accurate information such asviral load quantication, antibody titer

elevation and immunological reactions

to the disease which provide importantfeedback to support or modify the treat-

ment program.

Patients are placed in a hospital

environment prior to the whole-bodyhyperthermia procedure. Medical evalu-

ation is started at once.

Before the actual procedure

begins the anesthesiologist places the

patient under mild sedation. Two otherphysicians carry out the procedure with

the assistance and help of two nurses.The entire process takes approximately

4 to 6 hours.

After the procedure, the patient

is under constant observation with aphysician and a private duty nurse duringthe rest of the day and night. Other than

the effects of sedation patients should

not expect any discomfort and normallysleep over the following hours.

Laboratory tests may show

some changes following hyperthermia,

similar in nature to those observed afterhigh fever. However, as in fever, these

changes will return to normal in a few

days and scientic studies prove theyare inconsequential.

The day after the treatment mostpatients feel as they would feel after a

normal febrile episode: tired, sleepy, andwith mild aches and pains. All these

symptoms are mild enough not to require

any specic medication.

Thanks to careful surveillanc e

and monitoring during the procedurepatients rarely experience any discom-

fort. After a day, they normally resume

the level of activity they had before thetreatment.


Results from well formulated basic sc

entic studies and subsequent clinica

studies have demonstrated that heat aa therapeutic option is a viable alterna

tive. Heat therapy can be a tool whiccan be offered to many, but state-of

the-art technology, a professional staf

well trained in these protocols andprudent patient screening must rst be

developed in order to implement a safenontoxic procedure.

Chronic viral infections are th

other group of diseases in which treatment options at present are not only lim

ited but unfortunately are accompanieby short-term results. The prevalenc

of AIDS and Hepatitis C in the curren

world population provides the challengto seek effective alternatives to manag

and arrest the progression of these po

tentially fatal conditions.

We cannot stress enough th

importance of an accompanying protocoof detoxication, nourishment, immun

augmentation and overall well being athe foundation for more sophisticated

forms of therapy.

The nal determinat ion of th

value of this therapy in a particular cas

can only be decided by the interactionof doctor and patient together with the

appropriate analysis of clinical and labo

ratory ndings.

Those diseases that medicines donot cure are cured by knife, those

that the knife does not cure arecured by re, and those that re

does not cure must be considered

incurable.

Hippocrates


11/31

20

Advanced Diagnostic Assessmen

ADVANCED DIGITAL MICROSCOPY

IBC has been a world pioneer inthe use of digitalized, high-resolution,

phase-contrast optical microscopy forrapid monitoring and evaluation of condi-

tions. It has also been a research center

utilizing two of the blood tests particularlydesigned to use such an essay: the

"clot retraction" and "Iive cell" bloodtests or CRT and LCA.

The advanced medical micros-

copy used at IBC whose research anddevelopment involved IBC principals

over many years, it is a state-of-the-art system, including digitalization and

video monitor, which allows the clini-

cian to gather a tremendous amount ofinformation in a short period of time.

Sometimes erroneously called"darkeld microscopy" a reference

to one of its modes the system uses

drops of capillary blood expressedfrom the ngertip for the utilization

of the clot-retraction and live-cell tests,although the system is well tted for

medical microscopy in general.

The darkeld mode allows many

elements of blood not clearly visible in

the brighteld mode to come into clearview. At better than 15,000 magnica-

tion, the practitioner may see numerous

factors of living, circulating blood includ-ing red blood cells, white cells, platelets,

yeast forms, chylomicrons, cholesterolcrystals, bacteria, mycoplasma and

other structures.

"Live Cell analysis" hence allows the

physician to see in color and at extremely

high optical magnication a patient'sresponse to diet, medications and patho-

gens. Such evaluations allow for weeklyand even daily patient monitoring and

arguably diagnosis.

The more vintage "clot retraction"test, which has had various names, is uti-

lized at lower magnication to examine

the clotting factors in dried blood.

It has been determined that an

essential element in this test is the se-rum's response to "free radicals," which

are molecular breakdown products

common in the processes of oxidationand inammation. These compounds

which are normally generated by meta-bolic activity of the body can increase

substantially in a number of conditions

ranging from inammation to cancer.

ADVANCED DIAGNOSTIC ASSESSMENTAdvanced Digital Microscopy and the Augusti ReticuloEndothelial Prole, a peek into the future of diagnostics. bySalvador Chavarn, MD.

A theory that's gaining suppoholds that Cancer is

fundamentally a geneticdisease in which the normalgenetic mechanisms that

control cellular growthmaturation and senescence

have been disrupted.

They can also increase when the normalanti-oxidant system either fails or loses

efciency due to the presense of toxins

(tobbaco) or disease.

The appearance of coagulatedblood can indicate many pathological

conditions and/or the body's response

to therapies and healing.

Images from both CRT and LCA;

are digitally collected to produce picturesthat can be analyzed by the doctor with

the patient for his understanding of the

procesess and the result of the therapies.Hard copies will form part of the patient's

le for follow-up and comparison.

Experience has shown thatcertain conditions which would laterplague the patient in a visible, clinical

way were rst observed via the CRT

and LCA before standard laboratorytests detected them. Hence, the tests,

properly done with the advanced mi-

croscopy system, are often predictiveas well as diagnostic.

THE AUGUSTI

RETICULO ENDOTHELIAL PROFILE

Another state-of-the-art diagnos

tic tool that allows the clinician and thepatient not only to determine the status o

the condition but to follow the respons

to different programs is the "Reticuloendothelial Prole," also called the Augus

Test in recognition of the French scientis

who rst described, later standardizedand until today continues to improve th

test: Dr. Yves Augusti.

Normal red & white blood cells.Clumping of cells due t o enzyme deciencand resulting in poor blood ow.


12/31

22

Advanced Diagnostic Assessment

In this test, blood serum from

the patient is incubated at 9 different pHlevels (acid-alkaline) that will precipitate

different types of serum protein (alpha-

globulins). When any of these proteinsis abnormally abundant or scarce, it will

give, in the rst case, a turbid or an ex-

traclear solution in the latter.

These values, read by specialequipment, give us an overall perfor-

mance prole of important functions of

the body, such as the immune system,the liver, in ammatory processes, aller-

gies and even cancer.

The Augusti Test becomes even

more important in the follow-up treat-

ment, since it reacts to the same.

Different kinds of processes canbe followed as they increase in severity

or improve due to different programs

and critically important factors such asimmune performance, to the severity of

the inammatory process, reactivity to

allergic factors and activity or remissionof cancer can be all analyzed in order

to determine what direction future treat-

ments should take.

Many thousands of cases attest

to the performance and reliability ofAugusti's Reticulo Endothelial Prole.

Normal

High protein profile due to inflammatorymalignancy.

The development of vaccinesagainst disease has been one of med-

icine's high-water marks. And now

there is a new era in vaccinology whichincludes customized vaccines made

from tumors and traditionally prepared

cells that stimulate immune responses(Antigens).

Cancer is one of the areas whereresearch groups associated with Inter-

national BioCare Hospital (IBC) have

seen the most potential for DendriticCell (DC's) manipulation and response.

Science has shown that cells derivedfrom the specialized white blood cells

called Lymphocytes and Monocytes

produce tentacle-like elongations whichtrap tumor cells and expose them to the

immune system for destruction. They

are called Dendritic cells (DC's). Manyfactors in modern life may affect the

maturation process of DC's, renderingthe body more susceptible to the growth,

maturation and proliferation of tumo

cells. Every individual's cancer is unique

Therefore, the most effective treatment ione customized to a particular disease'

genetic conguration. By capturing thgenetic information of tumors, we ar

able to use DC's to trigger a desired im

mune response.

The Challenge of Cancer:Individual Cancer and Mutations.

Humans normally produce can

cer cells throughout their lives. Malignan

cells exposed to a healthy, active immune system will either be attacked and

destroyed (Phagocytosis) or geneticallprogrammed for self destruction (Apop

tosis).

Genetic mutations and chro

mosomal abnormalities are commonl

associated with human cancers. Unfortunately, since the genetic mutation

leading to the development of cance

are often random events, every patient'tumor can contain a unique repertoire o

antigens. The characteristic of humacancer requires each patient's immun

system to recognize the specic ant

gens present.

It is in this area of unique genetiprole, and the genetic mutations of eaccancer, that we capitalize our ability to

make Autologous Dendritic cell (DC's

cancer vaccines. The RNA-loaded DC'vaccine is customized to the unique an

tigen repertoire of each patient's tumoequipping the immune system to recog

nize and ght that particular disease.

DENDRITIC CELL (DC) VACCINESBushwhacking cancer from within

by Javier Vazquez, MD


13/31

24

Dendritic cell vaccines

Combining tumor cell-specicdendritic cell vaccines with atotal program which marshalsthe immune system in manyother ways while detoxifyingthe body, providing essentialnutrients and modulating theimmune system can stimulatethe natural process of healingto provide particularly impres-sive responses against degen-

erative diseases that plagueour times.

Because these vaccines include the

entire genetic repertoire of the patient's

tumor, they preclude the need to identifyor isolate specic tumor antigens. Thus,

with DC's vaccines, we can treat thosepatients without known tumor antigens

or those from whom insufcient tumor

material can be obtained, making themsuitable for the vast majority of cancer

patients.

Creating a Personalized Cancer

Vaccine:

The procedure involves drawingblood, from the patient. RNA-loaded

DC's vaccines start with precursors ofthe patient's DC's which, when matured

for the vaccine, are currently considered

the most effective antigen-presentingcells within the immune system. We are

then able to amplify tumor RNA from the

patient, whether from the primary tumorsite, distant metastatic sites, or from

tumor cells present in the circulation,

and transfect the patient's DC's with thepatient's tumor RNA.

This process offers the ability

for most cancer types at any stage of

disease to be target opportunities forthis cancer vaccine. At this point we

have created a weapon which, when in-

jected to the patient, will act as a cellularvaccine a "smart bomb" in modern

defense parlance.

Unique Advantages:

Dendritic cells transfected with RNA-encoding tumor antigens have been

shown to stimulate potent immune cell

responses equal or superior to othercompeting approaches.

The vaccine is completely Autologous,

potentially offering maximum safety with

practically no side-effects.

The vaccine targets the entire antigenicrepertoire of the tumor including "private

mutations" unique to the patient.

Formulation requires no specialized

manipulation maximizing patient partici-

pation (warm vial at room temperature,load syringe, inject).

International BioCare Hospital

is proud of its association with researchcenters from around the world whichhave brought to our patients this novel

and rational treatment program which is

so much in tune with the workings of theimmune system.

AUTOIMMUNE DEGENERATIVEDISEASES

Multiple Sclerosis, Lupus, Rheumatoid Arthritis and related condition

by Michael L. Culbert ScD

An important area of degenerative dis-

ease is one in which the defense or im-

mune system, far from being dormant oracting too slowly, manifests an increased

reactivity while at the same time ignoring

the normal target of its action ("non-self")

and instead turns on the self-compo-nents of our own bodies.

The result is autoimmune dis-

ease.

The immune system may be lik-

ened to a watchdog; a key virtue of theanimal is its ability to distinguish familiar

residents from intruders. The watchdog

that is dozing during a burglary is of nobenet to its master. Likewise, a dog s o

vicious that it does not distinguish be-

tween resident and visitor but may attackboth is an equal problem. This is what

happens in immune dysregulation.

Our immune systems develop

from the earliest infancy: as soon as weare born there are literally thousands

of "immunological challenges" we face

externally and even internally webreathe, eat or come in contact with them

in many ways through different organ

or tissues. That is, from the point of birtwe are under attack.

In the first weeks to month

following birth we are more or less pro

tected through the substances calledantibodies passed onto us from ou

mother's milk and which teach our de

veloping immune systems to distinguisself from non-self. These substance

even allow certain microbes to live and

thrive in certain organs because they areuseful, but others will be attacked and

expelled from the body.

So our immune system will grow

up with us, serving as a rst line of defense against disease. But various fac

tors can disrupt the normal maturation

process of that system: excessive use oantibiotics at an early age, replacement o

mother's milk by "formula" milk, the lacof or deciency in certain vital nutrient

such as essential fatty acids (EFAs), othe use of drugs and medications whic

may have a short-term benet but a long

term negative effect on the system.


14/31

26

Autoimmune degenerative diseases Autoimmune degenerative disease

All these elements may play a

role in the development of autoimmuneand "atopic" diseases.

From asthma to multiple sclero-sis, from lupus to rheumatoid arthritis,

immune diseases share in common a

high reactivity of the immune system with

a self target.

While medicine in general hasalways tried to curb the activity of the

immune system in general with the useof so-called immune suppressor drugs,

we believe that the treatment should

be directed toward helping the immunesystem respond in a more normal way

and to try to direct its activity against

non-self components.

In all immune disorders effortsmust be made to regulate a

dysregulated immune systemto again become an essential

part of our defense systemwhile restoring vitality to af-fected organs and tissues

Our treatment protocol for MS is

designed with various factors in mind:

The possible origins of the dis-

ease, the complications and problemsthe disease may produce, and specic

responses, such as the myelin sheath in

MS and the joints in rheumathoid arthri-tis. Each autoimmune disease normally

has its own most affected tissue or or-gan.

Even though the causes of

degenerative disease are obscure, weconsider that among the more important

ones are the immune system dysregula-tions in which one's own antibodies are

activated against various parts of the

body, such as the myelin sheath in MSor the collagen system. Indeed, since

collagen is an integral part of the con-

nective tissue which is the matrix whichsupports virtually every cell in the body-

we can say that it is universally located in

the body- collagen disease may producesymptoms in virtually every organ in the

body - from the skin to the liver to thekidneys.

Another theory of the origin ofautoimmune disease is that the antibody

response is triggered by viruses and that

in the presence of an altered immunesystem antibodies target tissues in what

are called "cross reactions".

With the increasing evidence

that viruses and/or mycoplasmas maybe "triggers" in these conditions, oxida-

tive agents can play essential roles in

therapy since they attack both.

In our protocols we are interested

in even subclinical infections -as in s uch

commonplace problems as infected

teeth and sinuses. Dysfunctional im

mune systems also allow the proliferation of Candida yeast and other microbia

infestations.

Once a diagnosis is in, oxidative thera

pies become key players since antibiotitherapy is counter-indicated. One of the

most effective of these agents, chlorine

dioxide, can both dismantle the viral omycoplasmic "trigger" and also relieve

the stress that infectious diseases ca

produce on an already overwhelmedimmune system. Ozone, hyperbaric oxy

genation and other oxidative substance

may also help in this process

We are interested insubclinical infections as insuch commonplace chronicproblems as infected teethand sinuses. Dysfunctionalimmune systems also allowthe proliferation of Candidayeast and other microbial

infestations. We also look forsources of toxic substances a

tobacco or mercury llings.

While IBC is not claiming "cure"

in MS or in rheumatoid arthritis,Sjogren's syndrome, lupus and other

autoimmune conditions in which "self"attacks "self" and all of which have re-

sponded favorably to IBC's treatments

its developing track record speaks foritself:

IBC protocols have been utilized,often with signicant results, in autoim-

mune disease in general and multiple

sclerosis (MS) in particular, with con-siderable experience developed in the

latter condition. In fact, over the yearspatients who were unable to walk due to

the deleterious effects of MS have been

able to regain that function.

Lives are lengthened, symptoms

are mitigated, suffering declines orceases, organ function is renewed.

In all autoimmune disorders,efforts must be made to regulate a dys-

regulated immune system as well asrestoring vitality to affected organs and

tissues.

Cytokines in rheumatoid arthritis


15/31

28

Autoimmune degenerative diseases

Optimal nutrition is providedas an important part of

the protocol. A key part inreversing the symptomsand restoring the normal

functioning of the immunesystem is provided by

essential nutrients that aresystematically depleted in the

so-called "western diet".

Our treatment program includes

providing alternative targets. For ex-

ample, certain snake venom derivativesdeect antibodies from normal tissue.

Several of these natural antigens packsuch a powerful punch that they can

shock and jumpstart the immune system

without any side effects to the host. Beevenom has also been positively used

with the same rationale in mind.

The use of live cell therapy (LCT)

helps reprogram the behavior of the

immune system to avoid the derangedresponse which produces the antibodies.

Since our main objective is to restore thehealth of the immune system, any effort

to restore its normal reactivity and its

ability to differentiate self from non-selfbecomes critical in obtaining a healthier

and long-lasting result.

Live cell therapy also helps repair

damaged neurological cells, joints, or

other organs affected so that symptomsare rst slowed and later reversed.

Optimal nutrition is provided as an

important part of the protocol. A key part

in reversing the symptoms and restoringthe normal functioning of the immune

system is provided by essential nutrients

that are systematically depleted in theso-called "western diet". With healthful

eating in mind as a central part of the

therapy program we start our patients onan intravenous protocol that will ll the

gap in the shortest time possible.

Daily intravenous nourishment

provides the missing or decient miner-als, vitamins, co-factors and essential

nutrients. A gluten-free diet is highly rec-

ommended and a vegetarian-oriented

diet rich in essential fatty acids, particu-

larly omega- 3 fatty acids and vegetable

protein and important phytochemicalssuch as lignans, are the foundation on

which long-term supplementation andlifestyle changes will provide healthy

living.

The treatment program is ac-

companied by a tailored detoxication

regimen and a special dietary program tohelp the body achieve peak performance

in ghting the disease while repairing

damage.

We cannot stress enough the

importance of a serious comprehensivein-house treatment program that can be-

gin changing the course of degenerativedisease. Our program that extends from

10 days to 2 weeks typically addresses

the different areas discussed in order torestore normal responses and behavior

in the immune system as well as heal

damaged tissue.


16/31

30

Victor Loustaunau, MD


17/31

32

In the 1980s patients and doctors

alike faced a completely new problem.All of a sudden and without any expla-

nation young people who in other times

would have been considered strong,healthy and very productive became

ill. The new illness did not follow a spe-

cic pattern but rather was a number ofsymptoms that altogether did not seem

to make much sense --at least to theeyes of physicians at that time.

Patients were also disoriented.Young professionals at the top of their

careers fell ill and became tired, de-

pressed, lost interest in all activity andgradually lost their jobs, social status and

even family lives. Worse, medical profes-

sionals failed to diagnose the problemand usual laboratory tests came back

consistently normal.

All this, along with a wide variet

of neurological signs, caused physician

to take the easy way out: The problemis in your mind, you will get over it; you

need a vacation and if all this fails loofor psychological help and take Prozac

they said.

What nobody seemed to unde

stand at the time was that we were facinga new entity, a number of illnesses somehow connected with the failure of the

immune system -- a new dysregulation

of this very important defense mechanism.

With the rst cases at our hos

pital, doctors immediately noticed tha

young, supposedly active people wereundergoing months if not years of partia

disabilities, had lost their goals in life an

evinced a group of signs and symptomnever before seen together in this popu

lation group.

The medical team decided tha

we were facing a new syndrome of greasignicance to which laboratory test

were oblivious.

The AIDS epidemic at the sam

time had brought about signicant inter

est in viral diseases and AIDS itself andherpes became important diagnoses a

the time. At the same time, this new

kid on the block seemed to be relatedto a widespread new and apparentl

unimportant virus: Epstein Barr. One othe clinical advantages about this new

virus was the fact that we already ha

available sophisticated tests to discoveits present level of activity and to deter

mine whether we were facing a new o

old problem.

A GUIDE TOCHRONIC FATIGUE SYNDROME

by Melba Romero, MD


18/31

34

The new interest in viral testingrapidly brought to light for our physicians

the fact that the new syndrome con-

sistently included an elevation of EBVtiters.

By then the term Chronic Fatigue

Syndrome had been coined and has

remained in place probably because itso accurately describes one of the most

important factors of this illness: periods

of extreme fatigue.

Chronic Fatigue Syndrome (CFS)

is the ofcial name given by the UnitedStates Centers for Disease Control and

Prevention (CDC) for a multifactorial dis-

order that in the USA was not recognizeduntil 1988.

CFS has had several names:

Epstein Barr Virus, Yuppie Flu, Chronic

Fatigue Immune Dysfunction Syndrome(CFIDS) and in many places Myalgic

Encephalomyelitis.

Its signs and symptoms can be

confused with such related conditions

as mononucleosis, thyroid dysfunction,chemical sensitivities, autoimmune dis-

eases and other viral conditions.

This dysfunction seems to be

mainly associated with several viruses.Among the more common are those

within the herpes family (EBV and HHV-

6) and less commonly the Enterovirusesand Retroviruses, but there may be other

infectious agents at work as well, includ-

ing mycoplasmas.

CLINICAL SYMPTOMS

The most important complaint ofthe CFS sufferer is energy loss, trans -

lated into a fatigue that does not improvewith rest, vacation, or entertainment.

This fatigue lingers for long periods of

time, and worsens with time.

Along with the fatigue other

symptoms -- mostly from the neuro-logical sphere-- occur: insomnia, depres-

sion, mood shifts, emotional instability

and personality changes are frequentsymptoms; unexplained sadness or guilt

or feelings of worthlessness and suicidalthoughts are not uncommon.

Other symptoms reflecting achronic, viral condition are frequently

present such as weakness, malaise, joint

pains, recurrent headaches, stomaches,sore throat, low-grade fever, swollen

glands, night sweats, cough and cold

symptoms.

These symptoms, and others,can occur in any combination and at any

intensity. For physicians the world over,

the protean span of signs and symptomsseen in apparently healthy young people

and with no apparent cause made it

frustratingly difcult to come up with asingle diagnosis.

Physicians were often faced withsuch a myriad of disturbances -- diges-

tive problems ranging from belching toatulence to diarrhea or constipation,

together with loss of appetite, and al-

lergy/sensitivity reactions which mightinvolve the skin, eyes, or other organs

and tissues -- that they could not grasp

the idea that they were dealing with asingle syndrome.

A Guide To Chronic Fatigue Syndrome

The easy way out was often asnoted to blame it all on the patients

mental state, write him a prescription

for an antidepressant or sedative, andrecommend psychological counseling.

Probably one of the best diagnos-tic clues for the physician is that CFS pa-

tients feel like they are not themselves.

They feel disoriented, do not understandwhat is going on and desperately seek

an answer.

ORIGIN

Our research suggests that CFShas multiple causes and that either new

or old reactivated viruses or mycoplas-

mas may be playing roles as catalysts

to a preexisting condition of general im-mune impairment, elements of which are

often related to prior or ongoing abuseof steroids, prior or ongoing abuse of

antibiotics (from medications or food),prior or ongoing abuse of recreational

drugs, elevated numbers of mercury

amalgam llings and/or root canals inthe mouth, continual overexposure to

industrial chemicals and/or herbicides/

pesticides, uoridated water, immuniza-tions/vaccinations, continual exposure

to low-level electromagnetic emissions

poor responses to anesthesia or in

compatible prosthetics, elements of thstandard Western diet, prior or ongoing

unresolved bacterial or viral infectionsprior or ongoing parasitical infestatio

and possible genetic predispositions.

One critically important fact ithat immune impairment can frequentl

cross-react with common viruses. Inmany cases an antibody intended to attack a foreign protein may in turn reac

against a normal component of the body

hence creating an autoimmune-like response.

For this reason autoimmun

symptoms and abnormal allergic reac

tions are frequently present. The formeexplain many of the neurological, mus

cular and degenerative symptomata

the later explain the multiple allergieseven the universal reactor syndrome

and many of the digestive problems ou

doctors encounter.

LABORATORY Early in the history of this syn

drome it was discovered that standard

laboratory tests did not provide andiagnostic evidence. This was a majo

setback that caused physicians to be

unaware of an abnormal process goinon. Due to the experience of alternative

physicians in dealing with viral, funga

and yeast infections, it became clear thaone of the major parameters observabl

in CFS was the level of Epstein Barvirus (EBV) titers that became react

vated. Epstein Barr virus is a relativel

widespread virus that is acquired early ilife and, due to the immune system, be

comes dormant for the rest of a health

individuals life.

A Guide to Chronic Fatigue Syndrome

Integrative physicians stressthat the origin of the illness iswithin the immune dysfunctionof the host, or patient -- andthat whatever relief that may

result from an attack on oppor-tunistic infections will be lostif the patients immunological

integrity is not restored.


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36

When the immune system un-

dergoes dysfunctional conditions, thenormally dormant Epstein Barr virus can

be reactivated, elevating the amount ofantibodies the body produces against it.

The same reactivation occurs with other

viruses such as human herpes-6 virus(HHV-6). It is unclear whether these are

actual causative agents or simply the

effects of an immune dysfunction.

Whatever, the laboratory assess-

ment of antibodies to them reects theongoing immune dysfunction, are factors

suggestive of diagnosis, and may beused to monitor progression or improve-

ment.

Another important tool that is

not only consistent with the syndrome

and for the same reason an importantdiagnostic tool, but also is probably the

most important piece of evidence that

convinced orthodox medicine that CFSis a real disease, is the Single Photon

Emission Computerized Tomography(SPECT) of the brain. This technologi-

cally advanced test conclusively dem-

onstrates dysfunctional brain activity thatimproves as treatment is provided. For

this reason it is a major monitoring test

for the CFS patient.

TREATMENT CONSIDERATIONS

Because of Internationa l BioCare Hospitals prior history in the de-

velopment of individualized, integrativemetabolic protocols, its approach to

Chronic Fatigue Syndrome was not long

in coming and it is based on the followingconcepts:

The illness probably has an im-

munological imbalance in which someof the following can play a role, in no

particular category of importance: Over-administration of antibiotics, steroids,

immunizations, mercury amalgam llings;

overconsumption of refined carbohy-drates, chemical additives; environmental

chemicals including cigarette smoke;

uoridated water; agricultural chemicals;hormonal manipulation; exposure to low

level electromagnetic frequencies; and, of

considerable importance, mental stress.

With these considerations inmind, the treatment is based on the fol-

lowing concepts:

Detoxication is a primary fea-ture of any therapy and in the case of

CFS the previous history of exposure

to chemicals, antibiotics, steroids etc.makes detoxification one of the key

factors in its successful treatment. For

the same reason avoidance of toxinsbecomes a major issue. Tobacco smoke,

alcohol, prescription and recreationaldrugs should be a major target of the

life-style manipulation elements in CFS

management.

Dietary manipulation, together

with detoxication, is the foundation of

any treatment intended to restore andbalance immune function. The proper

use of diet can never be overlooked.Food is not only the basis of energy and

building materials but is also the sourceof detoxification elements, immune

substances and balanced intestinal ora

-- all of which becomes the foundationof immune performance and equilibrium.

A healthy body and immune competent

system are unobtainable under poornutritional conditions.


Since opportunistic infections

seem to be the most apparent triggers

in many of the symptoms, the treatmentof these conditions becomes a priority:

EBV, HHV-6, mycoplamas, yeasts, and

candida are the most frequent and visibleinfectious elements in this syndrome.

Oxidative therapies are the best choice

for the treatment of these conditions.BI-OX, a powerful oxidative agent, has

become the treatment of choice for them.

BI-OX is a broad-spectrum antimicrobialoxidative agent which attacks all cell

wall-decient structures -- virtually allviruses, yeast/fungal species, various

bacteria and mycoplasma.

Ozone therapy has also been

very powerful in the treatment of theseproblems, together with the irradiationof blood with ultraviolet (UV) light. Ultra -

violet irradiation has a well-documented

antimicrobial effect.

An integrative approach uti-lizes all forms of attack against a broad

spectrum of microbes, yeasts and viral

infestations so strongly present in im-mune disturbances in general and CFS

in particular.

Integrative physicians stress tha

the origin of the illness is within the immune dysfunction of the host, or patien

-- and that whatever relief that may resufrom an attack on opportunistic infection

will be lost if the patients immunologica

integrity is not restored.

Hence, immune restoration is thmajor long-term objective for the CFSpatient. The attempt to regulate immun

function without detoxication, dietar

management and relief from pathogeninfestations will fail. Since mental stres

is increasingly and demonstrably seen tbe playing an important role in immune

regulation it must also be addressed

the patient is to have lasting results anfull recovery.

Recent research reveals thamost immunologically disturbed pa

tients are neither classically immune

depressed nor autoimmune-stimulatedrather, they are suffering the highs an

lows of dysregulation of the variouelements of what is called the immun

system.

Modern biochemical researc

also has made it clear that a vast rang

of nutriments and supplements -- vitamins, minerals, enzymes, amino acids

essential and nonessential fatty acids

phytochemicals, herbs-- are of positivbenet in either specic or nonspeci

immune regulation. Many nutritional elements classed as antioxidants or free

radical scavengers also exert a balanc

ing effect on immunity.

A Guide to Chronic Fatigue Syndrome


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38

Fetal cell extracts (live cell thera-

py) or their derivatives have been widely

used to balance the immune system.Beginning in the 1930s the late Paul

Niehans MD in Switzerland began usinganimal fetal tissue to produce overall

health benets in chronically ill and older

patients.

Modern cell-extraction and pres-ervation techniques have helped makelive cell treatments highly successful

in immune system augmentation. The

availability of such tissue-specic ex-tracts such as those from the thymus

gland is also of great help in the long-term management of CFS. Research

continues in these areas and under-

scores the importance of integrative andindividualized treatments -- an approach

which continues to lengthen our list of

successfully managed cases.

EXPECTED OUTCOME

A multifactorial program con-taining elements of the above --tailored

for the individual case-- can expect toachieve dramatic decreases in patho-

logical symptoms in a short period of

time. However, reduction in symptoms

is not the cure of a multifaceted syn-

drome of so many parts. Restoration ofimmune and endocrine balance is a long-

term challenge and can only be achieved

through adherence to a program ofproper diet, nutrition, supplementation

and proper lifestyle.


Our experience with CFS and re-

lated disorders is that the great majority

of patients show immediate short-termimprovement; smaller numbers improve,

relapse and improve again. CFS remainsthe most unpredictable and highly indi-

vidualized of chronic conditions.

The successful treatment of this

condition demands from the patient acommitment to intensive treatments,many hospital stays followed by an

at-home program accompanied by

discipline and a commitment to createa new lifestyle and improved health.

The do-it-yourself approach is usuallywasteful, expensive, frustrating and

unsuccessful.

At the present time, the innova-

tive, integrative, individualized program

synthesized here is securing the bestresults, and is optimistically aimed at

greater success in the future against an

awesome foe which has mostly bafedstandard medicine.

The nal determinati on of the

value of this form of treatment in any

particular case will be the interaction ofdoctor and patient and correct evalu-

ation of patient clinical and laboratory

ndings.

ULTRAVIOLET BLOODIRRADIATION PROGRAM

History, rationale and clinicaconsiderations of photoluminescence

by Victor Loustaunau MD

With over half a century as avaluable therapeutic weapon, exten-sive research reported in voluminousliterature around the world describesthe effects of ultraviolet blood irradia-tion on toxins, oxygenation and viri-cidal, bactericidal, and inammatoryconditions.

UV Blood Irradiation (UBI)was rst introduced in the 1930s tocombat the polio virus, but the adventof antibiotics and the Salk vaccineminimized its use. The new viral epi-demics and failure to treat a number

of conditions have brought back thepossibility of alternative forms oftherapy for these conditions. Chronicfatigue syndrome, hepatitis C, bacte-rial infections resistant to antibioticsand even such conditions as cancerhave shown good results with the useof UBI.

UBI is the controlled application oUV irradiation to the blood within thaccepted therapeutic UV band.

Applying ultraviolet rays directly to a patients blood was originally conceived as a method of utilizing the bactericidal properties of the

rays in the treatment of blood streaminfections. Recent developments inthe use of UV have led to a wellcontrolled procedure that produceexcellent results with virtually noside effects. Proper instrumentatioand training provide clinical resultin an inexpensive, fast and reliableprocedure.

The method of applying UVrays to the blood began in 1925 witha system that allowed circulation o

a minimum amount of blood out othe body through a device enablingthe operator precise control. Experimental work with dogs infected withdifferent highly infective bacteriaproved very effective and free of sideeffects.

The polio epidemic providea new opportunity for this methodIt developed rapidly and extensiveluntil immunizations eradicated it.

The method also ourishedin the 1930s when people dying ountreatable infections responded tothe therapy.


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Clinical effects and applications:

The effect of UV radiation onthe blood has been recognized and

well researched around the world.Probably the best known applicationsof UV irradiation are in the treatmentof infectious processes such as bac-

terial and viral infections. This is ofconsiderable signicance because ofthe presence of new bacterial groupsthat are resistant to classic antibiotictherapy. And there are viral epidem-ics that threaten younger groups ofpeople for whom alternatives are few.To mention a few: chronic fatiguesyndrome, hepatitis C, bromyalgia,encephalitis, and herpes infections,all of which respond to this therapeu-tic program.

UV irradiation has an im-portant detoxifying action that hasproven very important in chronicdegenerative diseases. Another im-portant effect is in peripheral vasodi-latation that increases blood ow inapproximately 75% of patients. Thiseffect, together with the increase of

blood oxygen by about 20%, meansthat chronic circulatory conditionscan be improved with minimal risk.Since this procedure involves nokidney damage whatsoever, diabeticchronic circulatory problems andolder people can easily be treated.Peripheral arteriosclerosis and evengangrene can be treated as well.

Criteria for entering the UV bloodirradiation program:

Patients who should benetclearly from this program are thosewith infectious processes resistantto antibiotic therapy, chronic viralconditions such as chronic fatiguesyndrome, hepatitis C, and HIVrelated conditions. We also targetthis therapy for people with chronicinammatory illnesses, chronic de-generative diseases and certainforms of cancer. Other targets arepoor circulatory conditions whereblood ow is poor and more aggres-sive techniques such as chelation oreven vascular manipulation could im-

ply a health risk to the patient. Olderpatients with vascular conditions andlower immune performance are alsogood candidates for this treatment.

Final considerations:

Ultraviolet irradiation of theblood is a valuable treatment tool thatmay prove to be an important alter-native in the treatment and manage-ment of difcult chronic infectious,inammatory processes and a num-ber of degenerative conditions wherehigher oxygenation levels and betterimmune performance are required.

Ultraviolet Blood Irradiation

HEPATITIS CTHERAPY PROGRAM

The integrative, complementary approac

by Javier Vazquez, MD

Hepatitis C is a viral illnessarising from contact with the virus,most often from blood transfusions.This infection is responsible for achronic illness that affects the liver.Infection with the Hepatitis C virus

(HCV) is a leading cause of chronicliver diseases worldwide. The mostremarkable and alarming aspect ofHCV infection is its high rate of viralpersistence and its ability to inducechronic liver disease.

Chronic Hepatitis C is diag-nosed clinically due to generalized

nonspecic symptoms such as fa-tigue, low grade fever, u-like mal-aise, abdominal fullness, digestiveproblems, indigestion, and a chronicdull pain in the liver area. Clinicaldiagnosis is often difficult at thebeginning because symptoms canmislead the physician to consider

other infectious problems or diges-tive disturbances. Conrmation ofthe diagnosis in the laboratory occurs

when there is a persistent elevation inserum transaminases in the presencof HCV antibodies. If these tests arequivocal and the disease is highly

suspected, viral load (HCV-RNA detection by PCR) may be conrmatoryIn many cases a liver biopsy may benecessary.

One of the primary goals oany therapy is stopping and ultimateleliminating the viral infection. Alongwith these therapies, a program tosupport liver function and the patients immune responsiveness wibe of great importance, particularlsince enhanced immune activity iable to arrest other forms of virahepatitis infections.

Oxidative Therapies are

the easiest procedures. This oftenimplies the use of BI-OX intravenously during a treatment period oabout 20 days. BI-OX is a moleculethat will release free oxygen into thblood when injec

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