icpermed-international consortium & l’iniziativa …erapermed consortium –32 members from 22...
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H2020 SC1 – Health, demographic change and well-being
Dr. G. GuglielmiDGRIC: Ministero della Salute
ICPerMed-International Consortium & L’INIZIATIVA SULLA MEDICINA PERSONALIZZATA
2
Personalised Medicine - Historic
CSA: PerMed(2013-2015)
ICPerMed(2016-2020)
CSA: ICPerMed Secretariat(2016-2020)
27 partners Including Industry, Researchers,
Funders and Ministries
Main output: Strategic research and Innovation Agenda (SRIA, 2015) with 5 Challenge Groups
28 countries partners→ Separation also in regions→ 6 countries observers
European Commission First main output: Action Plan
(Actionable Research and Support Activities)
4 countries Germany (coordination),
France, Italy (Health Ministry), Spain
Support for ICPerMed
1- Developing Awareness and Empowerment2- Integrating Big Data and ICT Solutions3- Translating Basic to Clinical Research and Beyond 4- Bringing Innovation to the Market5- Shaping Sustainable Healthcare
ERA-NET-Cofund 2018
Close connection
2017-2021 Tool to enable funding in PM
Venue
ICPerMedAim: to coordinate and foster research to develop and evaluate personalised medicine approaches
Over 30 European and international partners :
Representing ministries, funding agencies and the European Commission (EC)
International consortium model (similar to IRDiRC or IHEC)
Governance
Venue
ICPerMed – Development of the Action Plan
• 22 Actionable Research and 8 support activities
• Will feed into national and European strategic
discussion of research funders
First ICPerMed Workshop June 2017– Result and Dissemination base (MoH-It)
• In the short and medium term:
• to involve more European infrastructures for PM research, to expand
and improve BioBanking.
• Training of all stakeholders, including clinicians in the use of new
technology and Big Data dissemination.
• Development of shared policies for Informed Consent across EU,
design and implementation of new EU legislation on Data protection to
ensure that it supports PM.
• In the long term:
• Standardisation/Harmonisation of all steps of data production from the
patient to the final database.
ICPerMed Best Practise Recognition 2019– 2nd call
- Launched on 21st of November 2018.
- Deadline for proposal submission was 21st of January, with an extension until 4th February 2019
- Opened to applicants worldwide.
- Proposal published and/or developed between January 1st, 2017 and October 31st,
2018 were eligible to apply.
- Call topics have been aligned to contents of 2nd ICPerMed Workshop 2019.
- The first three selected proposals will be invited to the ICPerMed Workshop 2019 in Madrid and
will be given the opportunity to present their results during a plenary session. In addition, the
successful candidates will receive a non – cash support for the dissemination of the best practice
example by the ICPerMed Secretariat in the value of € 500
- Some projects will be selected to the Poster presentantion during the ICPerMed Workshop 2019
ICPerMed Recognition 2019: Overview ProposalsTotal Number applications received: 38 (18 call 2018)- at the first deadline ( 21th january 2019): 24- after the second deadline (4th february 2019): 14
58%
42%
Applicants : Gender Distribution
Female Male
4
1
1
2
4
4
13
1
2
1
5
0 2 4 6 8 10 12 14
Austria
Belgium
Canada
Estonia
Germany
Israel
Italy
Netherlands
Sweden
Switzerland
Turkey
Geographic distribution Applications
N. applications
RANKING LIST
Four successful examples (highest scores) for talk presentation
Number ID first author Institution Country/ RegionFinal
Score
Stand
Dev Rank list
ICPerMed_BPR_2019_32 Patrizio Giacomini
Oncogenomics & Epigenetics, IRCSS
National Cancer
Institute Regina Elena (IRE), Rome
Italy 4,7 0,9 1
ICPerMed_BPR_2019_37 Juergen BuschLudwig Boltzmann Gesellschaft,
AustriaAustria 4,6 0,2 2
ICPerMed_BPR_2019_14 Mark A.Rubin
Department of BioMedical
Research (DBMR), University of
Bern, Switzerland
Switzerland 4,5 0,4 3
ICPerMed_BPR_2019_17 Sulev Reisberg
Science for Life Laboratory,
Department Medical Sciences,
Uppsala University
Estonia 4,5 0,9 3
• RANKING LIST : 8 successful examples for poster presentation
Number ID first author Institution Country/ RegionFinal
Score
Stand
Dev Rank list
ICPerMed_BPR_2019_11 Dafna Ben Bashat Tel Aviv Sourasky Medical Center Israel
4,3 0,7 P1
ICPerMed_BPR_2019_21 Yvonne Bombard
Institute of Health Policy,
Management and Evaluation,
University of Toronto
Toronto 4,3 0,7 P2
ICPerMed_BPR_2019_05 Stefania Boccia
Institute of Public Health
Faculty of Medicine, U. Cattolica
del Sacro Cuore, Policlinico
‘Agostino Gemelli’ IRCCS
Italy 4,3 0,8 P3
ICPerMed_BPR_2019_30 Dom Dwyer
PRONIA Neurodiagnostics Group
Psychiatry & Psychotherapy
LMU MunichGermany 4,0 1,2 P4
ICPerMed_BPR_2019_01 Stefan FröhlingNational Center for Tumor
Diseases HeidelbergGermany 3,9 0,8 P5
ICPerMed_BPR_2019_29Nicola Gentili / Ilaria
Massa
IT Unit, Istituto Scientifico
Romagnolo per lo Studio e la Cura
dei Tumori (IRST) IRCCS, Meldola
Italy 3,7 0,1 P6
ICPerMed_BPR_2019_03 Maris AlverInstitute of Molecular and Cell
Biology, University of TartuEstonia 3,7 0,8 P7
ICPerMed_BPR_2019_31 Vera Damuzzo
Department of Pharmaceutical and
Pharmacological Sciences,
Hospital Pharmacy, University of
Padova, Padova, Veneto, Italy
Italy 3,7 1,6 P8
ICPerMed Recognition 2020
The launch of the “BEST PRACTICE IN PERSONALISED
MEDICINE" RECOGNITION 2020 will be on 5th of November 2019.
Deadline for proposal submission will be on 23th of January, 2020.
According to guidance of the ICPerMed Steering Board the call has been opened to applicants
worldwide.
Call topics have been aligned to topics of Paris Conference 2020
• The international scope requires the participation in ICPerMed of health research funding and
policy-making organisations from Europe and from other regions, as is the case of the CELAC
region (Community of Latin American and Caribbean States), addressed in this specific project
proposal.
• In this regard it is important to remark that the CELAC group of countries has been prioritized within
the Horizon 2020Work Programme 2018-2020,to promote this collaboration, in particular related to
the uptake of personalised approaches in health systems and healthcare, taking into account social
and cultural aspects, health economy issues and equitable healthcare.
• EU-CELAC PerMed work will be developed in close coordination with ICPerMed and ERA
PerMedinitiatives
EU-CELACPerMed:Widening EU-CELAC policy and research cooperation in PM
EULAC-PerMed, List of Partners
Participant No Participant organisation name Country1
(Coordinator)
Instituto de Salud Carlos III
(ISCIII)
Spain
2 Secretaría de Ciencia, Tecnología e Innovación Productiva de la Nación(SGCTeIP)
Argentina
3 Deutsches Zentrum für Luft und Raumfahrt, Projektträger /German Center forAerospace Research, Project Management Agency (DLR)
Germany
4 Fundação Oswaldo Cruz
(FIOCRUZ)
Brazil
5 Ministerio de Salute
(ITMoH)
Italy
6 Comisión Nacional de Investigación Científica y Tecnológica (CONICYT) Chile7 Sociedad para el Fomento de la Innovación Tecnológica (INNOVATEC) Spain8 European Clinical Research Infrastructure Network (ECRIN-ERIC) France9 National Research and Innovation Agency
(ANII)
Uruguay
10 Instituto Conmemorativo Gorgas de Estudios de la Salud Panama11 Chief Scientist Office, Ministry of Health (CSO-MoH) Israel
Widening EU-CELAC policy and research cooperation in Personalised Medicine
EULAC-PerMed Associate Partners and LTP
Associate Partner Country
Consejo Nacional de Ciencia y Tecnología
(CONACYT)
Paraguay
Ministerio de Educación
(MINEDU)
Bolivia
Laboratorio Nacional de Nanotecnología
(LANOTEC-CeNAT)
Costa Rica
Secretaría Nacional de Ciencia y Tecnología
(SENACYT)
Guatemala
Technical Research Centre of Finland Ltd
(VTT)
Finland
Ministerio de Salud Panama
Fundação para a Ciência e Tecnologia
(FCT)
Portugal
Link Third Party to ITMoH
Agenzia per la Promozione della Ricerca Europea
(APRE)
Italy
EULAC-PerMed Consortium
ACTIVITIES
Mapping
Training: 4 Summer Schools ( Italian Ministry of Health)
2 Common Methodologies´Workshops
1 ELSA Workshop
Relations with ESFRI landmarks and sister initiatives
Communication & Dissemination
1st EULAC-PerMed Summer School
“Personalised Medicine Research
in the Health System”
“Escuela Nacional de Sanidad” - ISCIII
Monforte de Lemos 5 – 28029 Madrid, SPAIN.
Madrid, Spain, 7th and 8th November 2019
Submission deadline: 15th July 2019
The event will be “back to back” with the ICPerMed 2nd workshop “Personalised Medicine for all citizens and patients within Sustainable Implementation”
Twenty researchers from European and LAC countries —priority given to those from LAC countries— will participate in a Training event with the aim of improving and sharing the appropriate knowledge and skills that will allow them to assess the impact of PM in the Health System in their countries.
It could be a chance to create research networking between EU & LAC countries.
For more information please visit: www.eulac-perme.eu
Save the date
EULAC PerMed will be holding three relevant events in December 2019 in Montevideo, Uruguay.
• 9th-10th December- EULAC PerMed Summer School: “Health Technology Assessment Research in PM”
• 11th-12th December- Stakeholder workshop: “Building Bridges In Personalised Medicine Between Latin America-Caribbean and Europe”.
• 11th-12th December- Technical Workshop “Innovative methodologies for data use and management in Personalised Medicine Research”
EULAC PerMed Summer School: “Health Technology Assessment
Research in PM”
• 20 researchers from European and LAC countries —priority given to those from LACcountries— will participate in a Training event with the aim of improving and sharing theappropriate knowledge and skills that will allowthem to improve understanding of the health technology assessment (HTA) processes toincrease the research skills contributing to the HTA process.
• The Summer School participation fee is free and open to 20 LAC & EU participantswho will be evaluated and admitted on a competitive basis.
• Each eligible applicant will be evaluated according to three criteria: academicpotential; experience in the Summer School topics; personal motivation (includingthe usefulness of this training in their current activity).
• The EULAC-PerMed will award a scholarship to six (6) participants. The successfulcandidates will receive non-cash support to cover accommodation costs and travelexpense.
• The documents to be submitted electronically (english) for this purpose are: theCurriculum Vitae; a clear reference to the candidate's academic qualifications; theapplication form with the candidate’s interest in participating in the Summer Schooland a Reference letter.
More information: María José Ruiz Alvarez ([email protected])
EULAC-PerMed
Widening EU-CELAC policy and research cooperation in Personalised Medicine
Participant No Participant organisation name Country1
(Coordinator)
Instituto de Salud Carlos III
(ISCIII)
Spain
2 Secretaría de Ciencia, Tecnología e Innovación Productiva de la Nación(SGCTeIP)
Argentina
3 Deutsches Zentrum für Luft und Raumfahrt, Projektträger /German Center forAerospace Research, Project Management Agency (DLR)
Germany
4 Fundação Oswaldo Cruz
(FIOCRUZ)
Brazil
5 Ministerio de Salute
(ITMoH)
Italy
6 Comisión Nacional de Investigación Científica y Tecnológica (CONICYT) Chile7 Sociedad para el Fomento de la Innovación Tecnológica (INNOVATEC) Spain8 European Clinical Research Infrastructure Network (ECRIN-ERIC) France9 National Research and Innovation Agency
(ANII)
Uruguay
10 Instituto Conmemorativo Gorgas de Estudios de la Salud Panama11 Chief Scientist Office, Ministry of Health (CSO-MoH) Israel
ERAPerMed consortium – 32 Members from 22 countriesAustrian Science Fund
Fonds de la Recherche Scientifique, Wallonia, Belgium
The Canadian Institutes of Health Research
Quebec Research Funds
Ministry of Science and Education, of Croatia
Innovation Fund Denmark
Estonian Research Council
Estonian Ministry of Social Affairs
Academy of Finland
The French National Research Agency
The Federal Ministry of Education and Research of Germany
The German Aerospace Centre e.V.
The Federal Ministry of Health of Germany
Saxon State Ministry for Higher Education, Research and the Arts
National Research, Development and Innovation Officeof Hungary
Health Research Board of Ireland
Chief Scientist Office, Ministry of Health of Israel
Italian Ministry of Health
Lombardy Regional Foundation for Biomedical Research
State Education Development Agency of Latvia
National Research Fund of Luxemburg
Research Council of Norway
National Centre for Research and Development of Poland
Executive Agency for Higher Education, ResearchDevelopment and Innovation Fundingof Romania
Ministry of Education, Science and Sport of Slovenia
Center for Industrial Technology Development of Spain
Department of Health – Generalitat de Catalunya
Regional Government of Navarre
Swedish Research Council
The Netherlands Organisation for Health Research and Development
The Scientific and Technological Research Council of Turkey
CO-ORDINATION: National Institute of Health Carlos III, Spain
ERA-Net cofund on
Personalised Medicine
ERAPerMed
Close Link Between ICPerMed and ERAPerMed
http://www.permed2020.eu/_media/PerMed_SRIA.pdf
http://www.icpermed.eu/media/content/ICPerMed_Actionplan_2017_web.pdf
Action Plan2017
SRIA2015
Recommendation of PerMed2020:
Only by including the whole value chain, we can move
forward in Personalised Medicine.
ERAPerMed – non EU co-funded JTC2019
TOPIC: PERSONALIZED MEDICINE: MULTIDISCIPLINARY RESEARCH TOWARDS IMPLEMENTATION
Comprises three Research Areas
Each consortium submitting a proposal must address at least one module of Research Area 3 and at least one
module of Research Area 1 or 2
Proposals must be interdisciplinary and clearly demonstrate the potential impact in Personalized Medicine as well as
the added value of transnational collaboration
ERAPerMed – non EU co-funded JTC2019
27 old Funding Partners + 4 Partners more
1 EU country: CSRT, Greece
1 charity: AECC-FC, Spain
Joint Call 2019 Secretariat (JCS):French National Research Agency (ANR)<[email protected]>
Funding Partners´ ex ante Budget: 32 M €
Timeline:
Launch: 9th January 2019
Two step procedure
Submission deadline for Pre-proposals: 7th March 2019
Submission deadline for invited Full-proposals: 17th June 2019
Expected start of granted projects: 2020 q1
1 region: TuscReg, Tuscany, Italy
1 third countries: ASRT, Egypt
ERAPerMed –EU co-funded JTC2018
Pre-proposal stage:
• 196 submitted pre-proposals ( 50 from It-MoH, 23 with italian coordinator) 933 partners requesting to 30 funding
organisations
• 216 M € requested funding
• 102 evaluators from institutions affiliated to 26 countries
• 33% females
Full proposal stage:
• 56 Pre-proposals invited to submit a Full proposal ( 11 from It-MoH, 6 with italian coordinator)
• Overall oversubscription factor for the full-proposal stage: 2.08
25 Project proposal funded with 28,271,516 € with 5 Italian partners final funded for the Italian Ministry of Health (IRCCS : Istituto Europeo di Oncologia (coordinatore), Burlo Garofolo, San Raffaele Pisana, Ospedale San Raffaele di Milano, I.S. Romagnolo per lo Studio e la Cura dei Tumori).
Ministero della Salute. DRGIC