iexplore: a provenance-based application for exploring biomedical knowledge

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iExplore: A provenance-based application for exploring biomedical knowledge Vinh Nguyen, Olivier Bodenreider, Thomas Rindflesch, Amit Sheth

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Page 1: iExplore: A provenance-based application for exploring biomedical knowledge

iExplore: A provenance-based application for

exploring biomedical knowledge

Vinh Nguyen, Olivier Bodenreider, Thomas Rindflesch, Amit Sheth

Page 2: iExplore: A provenance-based application for exploring biomedical knowledge

Why iExplore?

• Biomedical Knowledge Repository (BKR)

– Developed at NLM

– Integrating various knowledge sources

– Represented in RDF

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Page 3: iExplore: A provenance-based application for exploring biomedical knowledge

How to explore BKR?

• Large knowledge base

– 71 milliion triples in the BKR Instances

– 4 million triples in the BKR Schema

• Modeled from

– 2 million Metathesaurus concepts

– Semantic predications extracted from PubMed abstracts (2000-2009) by SemRep

• Broad domain coverage

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Page 4: iExplore: A provenance-based application for exploring biomedical knowledge

Approach

• Graph visualization

• Interactive exploration

• Explore either PubMed or UMLS

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Page 5: iExplore: A provenance-based application for exploring biomedical knowledge

Demo

iExplore is available at

http://knoesis.wright.edu/iExplore/iExplore.html

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Page 6: iExplore: A provenance-based application for exploring biomedical knowledge

Technologies

• Semantic Web

– RDF, SPARQL standards

– Virtuoso triple store

• iExplore development

– Client side: Adobe Flex

– Server side: Java

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Page 7: iExplore: A provenance-based application for exploring biomedical knowledge

Q&A

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