INAUGURAL PROTEA WORKSHOP Preliminary programme

Presented by the Department of Paediatric Cardiology, Red Cross and Tygerberg Hospitals

13th-15th March 2019

The Children’s Heart Disease Research Unit (CHDRU) was established in 2015 with the goals to: • Conduct, promote and support children’s heart research on the African continent• Facilitate Implementation Science• Provide postgraduate supervision and training in children’s heart research

The overarching vision, mission and values of this unit are those of the University of Cape Town and the Department of Pediatrics and the Institute of Child Health as our primary affiliations. Our vision and mission: Vision: integrating research and clinical practice to improve the lives of all with congenital and paediatric heart disease. Mission: conducting innovative, patient-centered and accountable research with the focus on African areas of need.

Two of our key projects are Reach and PROTEA.

Reach: To Stop rheumatic heart disease Reach was founded in 20143by Prof Jonathan Carapetis and Liesl Zühlke and is a scientific and technical initiative to achieve RHD control. Reach works across three strategic areas: people- supporting those living with and affected by RHD, Policy- ensuring ARF/RHD are national health priorities in endemic countries and Programmes-providing technical assistance on ARF/RHD prevention and control.

PROTEA: The Protea study Partnerships for Congenital Heart Disease in Africa (The PROTEA Study) aims to address gaps in evidence in CHD epidemiology by establishing a comprehensive phenotype and genotype registry, developing a biobank for DNA extraction and genetic analysis; and to utilise computational fluid dynamics to potentially develop new treatment modalities for CHD. A key component of this study is capacity building, teaching and training and expanding into other sites in Africa.

These two interests are brought together in this meeting: bringing together colleagues from South Africa and around the World to focus on novel research ideas to impact and change the lives of those living with Rheumatic Heart Disease and then providing some feedback and further training into Echocardiography as we demonstrate how research can impact clinical practice. Our meeting is funded by the University of Manchester and University of Cape Town, MRC UK and CHDRU and is dedicated to the memory of Professor Bongani Mayosi, a co-investigator on the Protea study and a tireless champion for RHD.

A warm welcome to the meeting and enjoy the warm Cape Town hospitality. A/Prof Liesl Zühlke Director Children’s Heart Disease Research Unit

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INAUGURAL PROTEA WORKSHOP Preliminary programme

Presented by the Department of Paediatric Cardiology, Red Cross and Tygerberg Hospitals

13th-15th March 2019

INTERNATIONAL FACULTY

PROF WILLIAM BORDER Director of Noninvasive Imaging, Children’s Healthcare of Atlanta (CHOA), Sibley Heart Center Cardiology Professor of Pediatrics Division of Pediatric Cardiology Department of Pediatrics Emory University School of Medicine

A/PROF NIGEL WILSON Division of Pediatric Cardiology Department of Pediatrics Starship Hospital New Zealand

PROF CRAIG SABLE Associate Division Chief of Cardiology at Children’s National Health System in Washington, D.C. Director of Telemedicine and Echocardiography Professor of pediatrics at the George Washington University School of Medicine & Health Sciences

OPENING ADDRESS PROFESSOR MAMOKETHI PHAKENG

Vice-chancellor University of Cape Town Professor of Mathematics Education Order of the Baobab (Silver) 2016 Most influential woman academic in Africa Businesswoman of the Year Award in the education category @Fabacademic

INAUGURAL PROTEA WORKSHOP Preliminary programme

Newlands Sun Hotel, Newlands, Cape Town Wednesday 13th March 2019

8am Registration

8.15am Opening and Welcome: Prof John Lawrenson Prof John Lawrenson Basic echo: Let’s get started

8.15am-8.45 am Setting up and switching on Ms Yanita Singh 8.45am-9.05am Ensuring high echo quality: what's easy what's

difficult Prof Will Border, USA

9.05am-9.25am Segmental analysis Dr George Comitis 9.25am-9.45am Basic LV and RV function Dr Barend Fourie

9.45am-10am Questions and Discussion Tea with hand-on (reserved places) Fenny Shidhika/Lenise Swanson

Evaluation of simple CHDs 10.30 am-11am An approach to Atrial septal defects Dr Fenny Shidhika, Nam 11am-11.30am Ventricular septal defects Dr Chris Hugo-Hamman 11.30-12.00am Coarctation of the Aorta Dr Jayneel Joshi 12.am-12.30am Atrio-Ventricular Septal Defects Dr Will Border

Lunch with hand-on (reserved places) Liesel Andrag/Yanita Singh

Evaluation of common CHDs

1.15pm-1.45pm Tetralogy of Fallot Dr Lenise Swanson 1.45pm-1.45pm Transposition of the Great Arteries Dr Harold Pribut 2.15pm-2.15pm Pulmonary Veins and TA/PAPVD Dr George Comitis 2.45pm-3.15pm Echo approach to Coronary arteries Prof Will Border 3.15pm-3.30pm Questions and Discussion Dr George Comitis

Tea with hand-on (reserved places) Shanaaz Omer/Mark Willoughby

Acquired Heart Disease and Advanced Techniques

3.50-4.10pm Fetal echo: fundamentals TBC 4.10-4.30 pm ARF versus RHD: Nomenclature matters Prof Nigel Wilson, NZ 4.30-4.50pm Basics of TOE Prof Justiaan Swanevelder

Fetal Echo: Fundamentals

INAUGURAL PROTEA WORKSHOP Preliminary programme

Thursday 14th March 2019

8am Registration

8.15am Welcome and Introduction to opening speaker A/Prof Liesl Zühlke 8.15 am -8.30am Opening address:

Vice-Chancellor of the University of Cape Town Prof Mamogethi Phakeng

Congenital Heart Disease 8.30am-9.00am Protea: Congenital Heart Disease Dr Thomas Aldersley 9.00am-9.30am Genetics of CHD A/Prof Gasnat Shaboodien 9.30am-10am Computational fluid dynamics: Introduction and

application Dr Malebogo Ngoepe/Liam Swanson

10am-10.30am CMR in CHD: Clinical application A/Prof Hopewell Ntsinjana Questions and Discussion -

Tea with hand-on (reserved places) Yanita Singh/Lenise Swanson Rheumatic Heart Disease

11 am -11.30am The Afrostrep register A/Prof Mark Engel 11.30 am -12.00am

RHD in Uganda: Research to clinical practice Dr Twalib Aliku, Uganda

12.am-12.30am Clinical cases and conundrums in RHD Prof Nigel Wilson, NZ 12.30 am -13h00 Rapid-fire poster session

Lunch with hand-on (reserved places) Liesel Andrag/Shenaaz Omer

Advanced Echo techniques

1.15pm-1.45pm Detailed echo in CMO/myocarditis LV: the Imhotep echo

Dr George Comitis

1.45pm-1.45pm Evaluation of the Right Ventricle in CMO Dr Barend Fourie 2.15pm-2.15pm Echo assessment of pulmonary hypertension in

Eisenmengers Prof Will Border, USA

2.45pm-3.15pm Echo assessment of the patient with GUCH Dr Blanche Cupido 3.15pm-3.30pm Questions and Discussion

Tea with hand-on (reserved places) Shanaaz Omer/Mark Willoughby

Research Frontiers in Echo

3.50 pm -4.10pm Speckle tracking basics A/Prof John Lawrenson 4.10 pm -4.30 pm Cardio - oncology - strain assessment for all? Prof Will Border, USA 4.30 pm -4.50pm Echocardiography in HIV Dr Amy Sims Sanyahumbi, Malawi 4.50 pm-5.00 Wrap-up followed by dinner for all delegates

INAUGURAL PROTEA WORKSHOP Preliminary programme

Friday 15th March 2019 PROTEA ADVANCED ECHO & RESEARCH CONCEPTS

08h30am-09h00am Point-of care echo in ICU: Assessment of CO and beyond

Dr Beyra Rossouw

09h00am-09h30am Double outlet right ventricle: Echo findings and implications for surgical approaches

Prof Craig Sable, USA

09h30am-10h00am Double outlet right ventricle: The view from the operating table

Dr Andre Brooks

10h00am-10h30am Innovative teaching concepts in Echo Prof Will Border, USA Tea

11am-11.30am Echo approach to heterotaxy Prof Will Border 11.30am-12.00pm Why we need an echo machine in the cath lab A/Prof John Lawrenson 12pm-12.30pm Advanced imaging- CTA and CHD A/Prof Hopewell Ntsinjana 12.30 pm -13h00 pm

Research Think-tank: What is needed in CHD research in South Africa?

Facilitators: A/Prof Mark Engel and Dr Chris Hugo-Hamman

Lunch 1.30pm-2pm Quality improvement strategies in Cardiac Surgery

in Emerging economies: Children’s Heart Link Ms Bistra Zheleva

2pm-3pm Echo quiz: Get prepared for your Certificate exam! Facilitators: Hopewell Ntsinjana & George Comitis

3pm-3.30pm Exercise stress echocardiography: utility in pediatric and adult patients with congenital heart disease

Prof Will Border, USA

Tea 3.50pm-4.10pm Detailed valve assessment: learning from an adult

echocardiographer Dr Blanche Cupido

4.10pm-4.30 pm Burnout and work-life balance among pediatric cardiologists

Prof Will Border, USA

4.30pm-4.50pm Medicine is an art: an introduction to Zeitz Mocca Art Curator: Ms Liesel Hartman 4.50 pm-5.00 Thanks and close A/Prof John Lawrenson