influencing patient safety in rural primary care clinics through computerized order entry

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Influencing Patient Safety in Rural Primary Care Clinics through Computerized Order Entry Matthew Samore, MD VA Salt Lake City Health Care System Professor of Internal Medicine Adjunct Professor of Biomedical Informatics University of Utah

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Influencing Patient Safety in Rural Primary Care Clinics through Computerized Order Entry. Matthew Samore, MD VA Salt Lake City Health Care System Professor of Internal Medicine Adjunct Professor of Biomedical Informatics University of Utah. Acknowledgments. Kim Bateman, MD - PowerPoint PPT Presentation

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Influencing Patient Safety in Rural Primary Care Clinics through Computerized Order EntryMatthew Samore, MD

VA Salt Lake City Health Care SystemProfessor of Internal MedicineAdjunct Professor of Biomedical InformaticsUniversity of Utah

Acknowledgments

Partners: University of Utah, Healthinsight, CaduRx Funding:

INFORM study: AHRQ R01 HS15413

Kim Bateman, MD Frank Drews, PhD Wu Xu, PhD Brian Sauer, PhD Shobha Phansalkar,

PhD Charlene Weir, PhD Jonathan Nebeker, MD

Amyanne Wuthrich Jose Benuzillo Warren Pettey Marjorie Carter Marci Fjelstad Rui Saito Shuying Shen

Outline Background

Conceptual framework Related work

Our active studies in patient safety Patient safety and health information

technology in rural settings: the INFORM study Methods

Participating clinics Health information technology Measurements

Results to date Summary and future directions

Conceptual framework Commonalities

Defining properties and functional capabilities are causal Internal component relationships are

deterministic Potentially predictable relationship between

internal components of system

Conceptual framework Differences

Adaptability How does system deal with change

Natural systems evolved No spontaneous change of defining parameters Adaptation as a result of unstable previous

states, to meet the changing demands placed upon by environment

Technical systems Intentional design and manufacturing to provide

solution to a specific, practical problem Suitable to perform a number of specific tasks

Conceptual framework Differences

Transparency Observers ability to observe and understand the algorithms

that govern a systems operation Natural systems

Non-transparent Algorithms describing component interactions and state

variables have to be deduced and are not fully understood Models – describe and mimic behavior

Engineered systems Designed for transparency

Relationships are planned and calculated during design process Despite transparency have complex systems sometimes

unpredicted and unanticipated emergent behavior Transparency affects the ability to cope with changes of system

Conceptual framework Differences

Linearity Mathematical description of the relationship

between output of system to its input Natural systems

Often display non-linear behavior Engineered systems designed to be linear

Makes it possible to solve linear problems analytically

Linear systems output can be predicted from input Allows application of reductionistic approach

Conceptual framework Differences

Predictability Allows for anticipation of future state of system

Natural systems More challenging to understand and modify Partly due to adaptive and non-linear nature Even simple natural systems difficult to predict

Engineered systems Easier to understand and maintain Higher complexity increases operator demand Maintenance and prediction are possible

Conceptual framework Clinical care delivery

Complex natural system that varies across myriad settings and care

Health information technology implementation Engineered system meets natural system

Our active studies in patient safety Medication management

Real-time detection of prescribing problems Medicaid population (Nebeker, Xu, and Sauer) VA health care system (Nebeker and Weir)

Clinical decision support systems in rural settings Primary care (Samore and Bateman) Nursing homes (Rubin)

Optimal laboratory monitoring intervals (Sauer) Error-producing conditions in intensive care

units, including interruptions and task ambiguity Medical device problems

Use of observation (Drews and Samore)

Methods INFORM study

Clinic-randomized trial to evaluate impact of computerized clinic order entry tool on clinical practice and office efficiency

Features of computerized clinic order entry tool Web-based writing of outpatient orders, including

prescriptions, immunizations, laboratory tests, X-ray studies, and work notes.

Accessible via any type of computer. Electronic transmission of orders to pharmacies and

other vendors or to local printers Common access to records across providers who

share patients while maintaining strict levels of confidentiality.

Methods: participating clinics Rural primary care clinics with

minimum of two providers were recruited None had pre-existing electronic health

records Eighteen clinics randomly assigned to

two groups Early implementation (launch in year 1) Delayed implementation (launch in year 2)

Post-launch, 2 clinics closed

Methods: participating clinics

Methods: health information technology user interface

Fumbling for his recline button, Ted unwittingly instigates a disaster.

Methods: provider home pageList of all refill requests your staff

has submitted for your approval Pt: Search for a patient record

Methods: refill requestsSelect patient name to review medication history

Select drug to review request and to edit, approve or deny

Methods: patient home pageA brief tour:

Status barNavigation commands Special functions

Active drug listFiltersStatus icons

Methods: drug favorites

Methods: drug interactions

Methods: mild drug interactions

Methods: measurements Observation of office processes

Efficiency of refill process Survey:

Theoretical framework of Information Technology Adoption Model (ITAM)

Focus groups “Time trials” using scenarios

Comparison handwritten and electronic prescription writing

Time-to-complete task Assessment of completeness, legibility, errors

Electronic prescriptions Chart review (Fall, 2007)

Methods: experimental scenarios Instructions for time trials

“For these scenarios, imagine that you’re with a real patient and work at your normal pace.”

Example: “Next you see a regular patient, Abigail B.

Cook. She is 74-year old with a history of rheumatoid arthritis. She also complains of pain when she urinates. The urine culture reveals that the she has a UTI due to E. coli that is resistant to fluoroquinolones. Prescribe an antibiotic to treat her UTI”

Results: impact on workflow Medication refill

system in one participating clinic before implementation of computerized clinic order entry

Post-implementation of computerized clinic order entry

Results

Results: survey Response to one of the questions

pertinent to patient safety: “Integrating drug reference and drug

interaction look-up with prescription writing is useful” 57% (26 of 45) strongly agree

(answered 6 or 7 on 7 point Likert scale) 9% (4 of 45) strongly disagree

(answered 1 or 2 on 7 point Likert scale)

Results: focus groups Favorable:

“We see the interactions. That helps quite a bit. So, that has made a difference a couple of times. Essentially changed my mind…”

“One thing I liked, that there was a medicine that I don’t prescribe very often and didn’t know about the dose…”

Results: focus groups Unfavorable

“it’s like getting those stupid things from the pharmacy…. It commented on too many menial, insignificant things that just waste your time…. Way too sensitive.”

“… the drug to drug reaction says “major” and you Look at other… look at ePocrates later and no reaction at all.”

Results: time trials 65 66

31

20.5

38

56.5

47.5

34.5

0

10

20

30

40

50

60

70

New familiar drug New unfamiliardrug

New dose Refills

Med

ian

Dur

atio

n (S

econ

ds)

CCOE PAPER

Results: drug interaction scenario Frequency with which trimethoprim/sulfa

was prescribed to elderly woman on methotrexate for rheumatoid arthritis Handwritten

11 of 13 instances Computerized clinic order entry tool

3 of 12 instances Recommendation of the Multum database

“Generally avoid”

Results: electronic prescriptions Analysis of instances of significant drug-

interactions is in progress Altogether:

430,000 electronic prescriptions 52,000 unique patients

Coumadin interactions 7 patients received coumadin and

amiodarone concomitantly 29 patients received coumadin and NSAID

(excluding celecoxib)

Summary and future directions Implementation is clinical care system

redesign Measures of impact

“Perceived usefulness” versus “average effect” “Experiment” versus “experience in the wild” “Errors” versus “adverse events”

Transition to health information technology that enhances patient-centered care