ingredient breakdown-updated.pdf
TRANSCRIPT
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Joylent is a ready to drink milkshake mix in powdered form to be mixed with water, with sweetener and added vitamins and minerals.Instructions for use: Mix 173g (3.5 scoops) of Joylent with 500ml water. Every bag contains 3 servings.Ingredients: oatmeal (gluten), Joylent Vitamix [Maltodextrin, Trisodium citrate * 2H2O, Sodium chloride, L-Choline bitartrate, Calcium carbonate (precipitated), Magnesium oxide (heavy),Vitamin C (ascorbic acid), Vitamin E 50% (dl-alpha-tocopheryl acetate, 500 IU), Niacin (niacinamide), Vitamin A (retinol acetate) 325000 IU, Pantothenic acid (calcium-D- pantothenate), Vitamin D3, Copper sulphate, Vitamin K1 5%,Vitamin B1 (thiamine mononitrate), Vitamin B6 (pyridoxine hydrochloride), Vitamin B2 (riboflavin), Potassium iodate, Chromium chloride, Folic acid, Biotin, Vitamin B12 (cyanocobalamin)], soy flour, whey protein concentrate (cow's milk, lactose, soy lecithin, sucralose, flavor aroma, natural dye, thickener: guar gum), ground flaxseed, flavour enhancer [flash-dried fruit powder (strawberry/banana [5%])/vanilla powder/raw cacao].Allergens: may contain traces of nuts (peanuts).
Sources:
Oatmeal - plant - Avena sativa
Whey Protein concentrate - cow milk- animal - cow
Soy flour - plant - Glycine max NON GMO
ground flaxseed - plant - Linum usitatissimum
flash- dried fruit powder (strawberry/banana [5%] - Fragaria ananassa/Musa acuminata Vanilla powder - plant - V. planifolia
Cacao powder - plant - Theobroma cacao
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Vitamin Mix
Maltodextrin maize or wheat/ maize
Sodium chloride synthetic flow chartCalcium carbonate (precipitated) synthetic, mineral flow chart
L-Choline bitartrate synthetic flow chartMagnesium chloride * 6H2O synthetic origin, composition
Potassium citrateplant (Maize, Sugar Beet), mineral flow chart
Magnesium oxide (heavy) synthetic flow chart
Vitamin C (ascorbic acid)vegtable (corn) => fermentation
Vitamin E 50% (dl-alpha-tocopheryl acetate, 500 IU) vegtable (maize), synthetic
Potassium iodate synthetic n.a.
Niacin (niacinamide) synthetic flow chartVitamin A (retinol acetate) 325000 IU
vegetable( beet sugar, maize, acacia), synthetic) flow chart
Vitamin D3
synthetic, vegetable(maize, sugar cane, coconut), animal wool grease (fat) flow chart
Pantothenic acid (calcium-D-pantothenate) synthetic flow chart
Folic acid petrochemical flow chart
Chromium chloride synthetic n.a.
Biotin synthetic flow chartVitamin B12 (cyanocobalamin) fermentation flow chart
Vitamin K1 5%synthetic, vegetable(maize, acacia) flow chart
Vitamin B2 (riboflavin) vegetable (maize starch)
Copper sulphate synthetic flow chartVitamin B6 (pyridoxine hydrochloride) synthetic
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Basic flow-chart: SodiumPlant: dsalz GmbH, Bad
chloride Ph.Eur./UPFried richshal llGermany ffi4ffi W&dgffifu.w
Rock salt feed
Dissolving
Sedimentation
Evaporation I Crystallisation
lnsolubles(Clay, anhydrite,magnesium hy-droxide)
Fines, graineswith oversize
Rock salt means sodiumchloride with the main naturalimpurities clay and anhydrite
Dosage of sodium hydroxide(pH regulation) and flocculant
Dosage of antifoam additive(silicone product)
Slurry (Sodium chloride / Brine)
Debrin ing (centrifuges)
Drying (hot air)
Cooling (cold air)
Packaging25 I 50 ks PE baqs,
Sodium chloride extra pure,without anticaking agent
{-- Final inspection and test
Version: 19 May 201O/Dr. Gtzfriedleg
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Vitamin D3 100 SD
Emulsification (High-pressure)
Holding
Spray Drying
Sifting
Packaging
Preparation of Matrix (water soluble
components in water)
Preparation of Oil Phase
Temperature control
Screen size
Production route: Vitamin D3 100 SD
Nut
race
utic
als
Pressure control
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Herstellungsmethode (Calciumcarbonat, schwer, Magnesia 449):
Calcit
Zerkleinern
Trocknen
Siebung
Mahlen
Analysieren, CaCO3
Verpacken
Comments on the production process: Only natural Calcium carbonate (CaCO3) from 5 m to 4 6 mm is micronized. Raw material in stones of 10 cm arrives in the main plant from the quarry, 8 km far, and here it starts to be micronized. Micronization takes place in two different lines: technical line and pure line. In the technical line all products for technical market are obtained, while in the pure line only products for both food and pharmaceutical market are manufactured. Both lines are completely closed and separated and no contaminations are possible. Thanks to the dry and friable raw material, during the process no liquids or chemicals are used and only compressed air is used for cleaning machinery. In the process there are three metal detectors. They are able to detect only ferrous materials, whereas for the pure line a glass procedure is in place. The plant works for 24 hours per day, 7 days per week. Maintenance is done during summer time and winter holidays when machinery is off. Controls of critical steps: Raw material: chemical analysis In-process-controls: periodically throughout the manufacturing process; physical analysis and insoluble matter in acetic acid Finished product: chemical and physical analysis
71805
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Seed culture in mother bottle culture
Primary seed culture
Second seed culture
Fermentation
Continuous lysis
Membrane filtration
Adsorption in column
Eluate vacuum concentration
Transformation Concentration eluate collection
Fermentation broth Primary acidification
Zhejiang Medicine Co., Ltd.
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Flow Chart of Biotin Pure
Debenzylation Adjust pH inaqueous layerCheckingmaterials
Recoveringhydrobromic acid
Storage inwarehouse
Storage inPlant
Receiving byPlant
Checkingequipments
Dropping liquidcaustic/Keeping PH Filtration
Extracting/Demixing
Crystallization/Centrifugalization
Refluxing/Filtration MillingDrying Sampling
Storage inPlant
Transport tocustomerPackaging
Storage inwarehouse
Dibenzyl biotin/Hydrobromic acid
HB/Methylbenzenesolution
Water/ Activatedcarbon/EDTA
Raw material/Packaging material
Biotin crude
Test by QC Release byQA
Extraction
Water/Methylbenzene Liquid caustic
Thermalinsulation
CCP2CCP1
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Version 05.11, supersedes 04.07 -1/1- TPC_G10_EN
Production Flow Chart Tripotassium Citrate
citric acid, potassium source, water
neutralization crystallization centrifugation
sieving packaging drying
Detailed Flow Chart
A. A1 station:
NO2
COCl
p-nitrobenzoyl chloride
Alkali liquor Water Monosodium glutamate
The layer of Toluene
Hydrochloric acid (Ind. Grade)
Iron powder
Ammonium chloride
Toluene
Hydrochloric acid (Ind. Grade)
Condensation
Reduction
Recollect
Distillation
Stand to delamination
Adjusting
Temperature Preservation
Salt formation
Filter
Decolorization
Filter
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For information only not for regulatory purposes no update service - August 2005
Human Nutrition Flow Chart: Dry Vitamin A-Acetate 325 GFP/E Manufacturing site: BASF Health & Nutrition, Denmark
Atomization
Emulsion of Vitamin A-Acetate
Powdering agent Air
AirDrying
Mixing of dried batches to standard
Dry Vitamin A-Acetate 325 GFP/E
February 2012
CONFIDENTIAL
Choline Bitartrate Processing Flow
Manufacturing site: Balchem Italia srl
Via del Porto snc 28040 Marano Ticino (NO) Italy
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JIANGXI TIANXIN PHARMACEUTICAL CO.,LTD
Add.: Leanjiang Industrial Zone, Leping, Jiangxi, China P.C.: 333300 Tel: +86-798-6702928 Fax: +86-798-6702928 E-mail: [email protected] Website: http://www.txpharm.com
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Process Chart of Pyridoxine Hydrochloride
Remark: CCP is the Milling process. Inside the milling machine there is a screen. The integrity of the screen and the remains of material on the screen are inspected and recorded for each batch production.
Starting materials: 4-methyl-5-ethoxyoxazole, n-propyl dioxepin Flow chart:
4-Methyl-5-ethoxyoxazole
n-Propyl dioxepin
Addition reaction Aromatization
Hydrolysis Purification Drying
Milling/Sieving
Finished product
Ethanol
Human Nutrition Flow Chart: Calcium D-Pantothenate Manufacturing site: Ludwigshafen, Germany
For information only not for regulatory purposes no update service - January 2005
Crystallisation
Water
Methanol
Calcium D-pantothenate
Spray drying
Calcium -alaninate D-pantolactone
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Manufacturing Flow Chart
Dry Vitamin K1 5% GFP PRD no. 30041002
Manufacturing site: BASF A/S, Denmark
This document, or any answers or information provided herein by BASF, does not constitute a legally binding obligation of BASF.
While the descriptions, designs, data and information contained herein are presented in good faith and believed to be accurate, it is provided for your information only and not to be used for purposes of pharmaceutical registrations.
There is no automatic update service for this information.
SELLER MAKES NO WARRANTY OF ANY KIND; EITHER EXPRESS OR IMPLIED, BY FACT OR LAW, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR PARTICULAR PURPOSE.
Emulsion of Vitamin K1
Atomization
Drying
Sieving
Dry Vitamin K1 5% GFP
Powdering agent Air
Air
Version 1, 03.2011
Flow chart of Niacinamide manufacture process
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Version 12.07.2012 Kn/VS FS-C46-Et-2.doc
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METHOD OF MANUFACTURE
Magnesium Oxide, heavy
Magnesium Oxide
Demin. Water
Suspension
Purification
Drying
Packing
The raw materials are ordered by the Dr. Paul Lohmann GmbH KG according to internal specifications or pharmacopoeia, controlled by Quality Control and released for production thereafter. Only Demineralised Water is used as a cleansing agent and solvent. The final product is analysed by QC according to methods of specification or pharmacopoeia. If all tests comply with the limits, the material is released for shipment.