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Gjhl`en Od}kl`nehwne2 Exdcejduy

ljn Ejndcejduy NJL Lnnui~y ljn

Evgceje~gi L`~e}l~gdjy dokgi}d]JLy

Blkey Ysejme}c, N*_*K*, Vh*N*

bysejme}Feklg`*uji*enu

7

8/2/2019 Inhaled Formaldehyde Exogenous Endogenous DNA Adducts Epigenetic Alterations of MicroRNAs by Jim Swenberg

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Kd}e ~hlj =6 kg``gdj ~djy$wel} dood}kl`nehwne gy v}dnuien sd}`nsgne ljnuyen gj l sgne yvei~}uk do lvv`gil~gdjy*

^he}eod}e, od}kl`nehwne exvdyu}ey o}dk

ejg}djkej~l` ljn diiuvl~gdjl` ydu}iey

l}e |ug~e idkkdj*

Od}kl`nehwne gy l ajdsj ljgkl` ljnhuklj il}igjdcej, iluygjc jlyl` iljie}*

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6

6

56

?6

36

6 = > ? 8

8/2/2019 Inhaled Formaldehyde Exogenous Endogenous DNA Adducts Epigenetic Alterations of MicroRNAs by Jim Swenberg

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Od}kl`nehwne gy l umg|ug~duy ejg}djkej~ vd``u~lj~, mu~ g~ gy l`yd ljeyyej~gl` ke~lmd`g~e gj l`` `ggjc ie``y* ^he}eod}e, md~h ejndcejduy ljn

exdcejduy od}kl`nehwne jeen ~d me idjygne}en gj }gya lyyeyykej~*

Od}kl`nehwne gy e}w }eli~ge sg~h v}d~egjy ljn NJL, `elngjc ~d nge}yev}d~egj lnnui~y ljn NJL nlklce*

c`u~l~hgdje

Y+hwn}dxwke~hw`+c`u~l~hgdje

LNH9

Y+od}kw`c`u~l~hgdje

Y+od}kw`c`u~l~hgdjehwn}d`lye

od}kl~e

ID=!H=D

c`u~l~hgdje

ejndcejduyydu}iey

exdcejduyydu}iey

L@NH

8/2/2019 Inhaled Formaldehyde Exogenous Endogenous DNA Adducts Epigenetic Alterations of MicroRNAs by Jim Swenberg

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Exve}gkej~l` Neygcj

]l~y se}e exvdyen ~d

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Yiheke

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Gkv}den Ke~hdnd`dcw @DN2 =6 l~~dkd`ey @D\2 >6 l~~dkd`ey

Gjy~}ukej~l~gdj Sl~e}y JljdLi|ug~w UV@I Sl~e}y I kgju~e }ee}ye vhlye c}lngej~

Kdmg`e Vhlyey2 L' Sl~e} sg~h 6*

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8 7

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]l~gd do Exdcejduy ~d EjndcejduyLnnui~y

6

6*5

6 ?6 86

`j

(ExdcejduyL

nnui~y$! ie``y ~d ey~lm`gyh ejndcejduy lnnui~lkduj~y*

Huklj mdje kl}}ds ~d idkvl}e sg~h kdjaew nl~l*

Huklj jlyl` ~u}mgjl~ey ~d ey~lm`gyh ejndcejduy lnnui~lkduj~y*

L v}gkl~e y~unw ~d exlkgje y~ek ie``y gj IN 9>! v}gken

kdjaewy exvdyen ~d Q

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=8

]evlg} do L`nehwne NJL @eygdjy

]gnvl~h, B] e~ l`(=663' Iljie} ]ey

6

=+EY 57>8'

JGEHY Iej~e} od} Ejg}djkej~l`Hel`~h ljn Yuyiev~gmg`g~w (V96

EY