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Innovation WHERE, HOW, AND WHY WE INNOVATE May 18, 2017

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InnovationWHERE, HOW, AND WHY WE INNOVATE

May 18, 2017

How can we embrace

change and createbetter

value for our patients?

For 140 years, the Sisters of OSF have been serving their

communities with compassion and humility. The Sisters have

neverbeenafraid of taking on the hardest challengesand

providing care to all those who needed it. It’s no surprise, then,

that when the paceof change in health care is faster than ever,

when technological andscientific innovation are enabling so

much, that we would take astep back to examinehow we can

leverage these advances for the benefit of our patients.

OSFlaunchedOSFInnovation asameans to embrace changeand

take on the largest health care challenges; the ones that require

innovation andadifferent way of thinking to solve.

In the spirit of Christ and theexample of Francis of Assisi, the

Mission of OSF HealthCare is to

serve persons with the greatest

care and love in a community that

celebrates the Gift of Life.

WHY

Kickin’ it ol’ Skool…. VBP via a capitated payment…

…and a narrow network

It’s 1905….

We define innovation as...

WHY

HOW:ENVIRONMENT

A culture forinnovation and learningWhetherpossibilities aregenerated byanOSFteam,anewstartup, or a

combination,we provide awork environment that is healthy, flexible, high-

performing andhighlycollaborative. Whether in ourWORKplace, abalanced

approachfor creating effective work environments for our office-based

Mission Partners or oneof our simulation environments for clinical

exploration and learning, we have made intentional environments for

innovationand learning. Weare innovators for life.

Surgery Simulation Space Patient Room Simulation Space

NICU Simulation Space EmergencyTransport Simulation Space

6 I

Enhance relationships with Health Technology and Health Devices Entrepreneurs as well as Commercial health care entities to advance Ministry strategy by influencing the design of solutions for early identification and adoption.

Innovation Space

serve. connect. transform.

Here are a fewmembers of the innovation leadership team

Michelle Conger ChiefStrategy Officer

OSFHealthCare

JeffryTillery, MDSeniorVicePresident

ChiefTransformationOfficer

OSFHealthCare

[email protected]

BeckyBuchenVice President

PerformanceImprovement

OSFHealthCare

[email protected]

StanLynallVice President

Venture Investments

OSFHealthCare

[email protected]

Matthew Warrens Vice President

Innovation Partnerships

OSFHealthCare

[email protected]

JohnVozenilek, MD FACEPVicePresidentCMO

JumpTrading SimulationandEducation

OSFHealthCare

[email protected]

Lisa Barker,MDCurriculumDirector

JumpTradingSimulationand

Education

OSF HealthCare

[email protected]

William Bond,MDDirectorof SimulationResearch

Jump Trading Simulation and

Education

OSFHealthCare

[email protected]

Thenkurussi Kesavadas Director of HealthCareEngineering

University of Illinois at Urbana-Champaign

[email protected]@osfhealthcare.org

Matthew Bramlet,MDDirector

Advanced ImagingandModeling

OSFHealthCare

[email protected]

Mark HohulinSenior Vice President

Healthcare Analytics

OSF HealthCare

[email protected]

WHO

Paul PribazVice President

Simulation Administration

OSFHealthCare

[email protected]

Sarah de Ramirez, MD MPH MScVicePresident

Transformational Innovation OSF

HealthCare

Sarah.A.StewartdeRamirez@

osfhealthcare.org

How are we organizing our innovation teamOutside Innovation Partners

• Partnerships with outside companies• Shared innovation methods• Collaborative co-development of

solutions• Immersive design• Shared risk and reward

Breakthrough Innovation

• Developing concepts and inventing things for markets that don’t yet exist

• Create greater efficiency or cost savings with current processes or products through disruptive innovation

• Transform care and existing models• Employ new technologies and ventures• Create innovation fellowship

Core Innovation

• Optimize existing products, processes or assets for existing customers

• A culture sustaining acts of creativity• Targeted at core activities• Continual application of innovation to

recurring details

Venture Capital

• Seeks and manages funding for start-ups with long-term growth potential

• Review business plans• Perform due diligence• Track investments• Ensure venture is meeting milestones• Validates ROI on portfolio

Simulation and Education

• Develop artificial representation of real world process

• Research strategy and grants• Utilizes simulation-based learning

practices for training and beyond• Simulation-based clinical research• Deploys cutting edge technology

Doctor-patient relationships

with disadvantaged patients

who are intimidatedbyhospitals

and doctors

Engagement with

patients from

different cultural

backgrounds

Expansion of care to

uninsured individuals

and families

Building healthy

communitiesoutside

the hospital as well

as inside i t

Motivating individuals

so that health careis

seenasa community

responsibility

For exampale, HealthBegins

partners with LA high school

students to understand

community health problems and

localmedicalresources

Clinicians’ ability to

access other Mission

Partners’ expertise and

capacitywhile thepatient

iswith them

More effective

caregiver - patient

communications and

services outside of

appointments/ office

visits

Alternative

transportation

partnerships to help

rural patientsget

accessto care

Patients’ ability to

optimizethetreatment

process before they

reach theclinician

Connections to

patients that are

indigent, immobile,

or have no address

Forexample,RuralHealth

Initiative isaremote clinical

supportsystem, basedon

asharedbackground

OSF innovation teams could explore…

Recreating diverse

environments to

understand peoples’

reactions and behaviors

Simulation-based

clinical research to

learnfrom rarecases

Disaster response

procedures that are

tested before being

put intopractice

Cutting edge

technology that

improve clinicians’

empathy of

conditionsNew tools and services

to train Mission Partners

For example: Health Scholars is an

interactive, standardized, learning

encounter for preceptors and nurses built

on a measurable, self-contained mobile

platform

HOW:TEAMS

Clear focus anddirection are essential for successful innovation.

We have four focus areas of innovation for our Mission Partners,

external partners, and innovators. These areas guide our

investments and activities in innovation, ensuring they serve the

most important needsof our community.These four areas demand

innovation; we will not advanceour Mission herewithout it.

WHAT

We are focusing on four

innovation priorityareasAdvancingSimulationHow can OSF use simulation

beyondeducationto transform

healthcare?

Aging inPlaceHow can OSF deliver care to

the elderly without disrupting

where and how they live?

More for Those with Less How can OSFbest serve its most

disadvantaged populations?

Radical Access to Care How can OSF radically

democratize access to care,

regardless of setting or context?

Simulation in nursing education

creates a higher level of knowledge and

competence in nursing practice

Ourpopulation and their needs

Simulation has the power to radically improve the way we deliver

care, our ability to cut care costs, and the way we train and

develop providers—at OSF and other institutions. Innovation

here has the power to not only dramatically change the health

care industry, but also create new sources of growth and funding

for OSF.

SUPPORTING DATA

19.1%SIMULATION MARKET CAGR2014–2019

“Simulation is a technique, not a

technology, to replace or amplify real

experiences with guided experiences,

often immersive in nature, that evoke or

replicate substantial aspects of the real

world in a fully interactive fashion”

WHAT

Advancing andReimagining

Simulation

HowcanOSFusesimulation beyond

education to transform health care?

OSF has committed to leading the development and use

of simulation technology and services in health care.

Innovation in simulation can push the boundaries of

education, training, and research, but also teach doctors

empathy and add to our understanding of human behavior.

Training and education simulation is only the beginning.

OSF is leveraging disruptive technology to become a

destination for simulation innovation—and in doing so,

not only advance its own capabilities, but convert them

into valuable products and services for other institutions.

$2 BILLIONThe estimated medical simulation market (2019)

Revolutionizing partnerships

between clinicians and

engineers to stimulate

advancement of health care

New Skills and new partners on our Team

Jump Applied Research for Community Health through

Engineering and Simulation (ARCHES) is a collaboration

with the University of Illinois at Urbana-Champaign’s

Collegeof Engineeringand Collegeof Medicine at Peoria.

Focusing on the technologies and techniques of clinical

simulation and its impact on patient care, ARCHES is

creating new tools using imaging, health information

technology, novelmaterials andhuman factors to enhance

medicalsimulation andeducation.

About 20-25% of patients

discharged from hospitals are

readmitted within 30 days

costing roughly $42 billion

per year to insurance providers

• Most companiesarenotsetupto explore or

commercialize things that are new to the world,

evenif thepromiseishuge

• Involvesthegreatestamountof risk and

degreeof uncertainty

• Delivers thegreatest returns whenyouhit it right

• Comprisesasmallernumberof initiatives drivenby

focusedresources

Falls are a leading cause of

serious injury and death

in the elderly, especially when

they are at home alone

• Collaborationof University of Illinois Colleges of

EngineeringandAppliedHealthSciences(UIUC),

Illinois Neurological Instituteat OSFHealthCare

• Assessfall risks andpredict falls

• Utilizes camera-capturemotion data of

participants inhomeenvironment

• Targetedinterventions inanindividualshome

IDENTIFYING FALLRISK

IMPROVING THE PATIENT DISCHARGE PROCESS

Viewing medical images using

immersive and visual technologiesAdvanced Imaging and Modeling (AIM) has garnered nationwide attention.

Thanks to a generous gif t , creating the Shepard endowment, AIM

beganin 2013 whenpediatric cardiologist Matthew Bramlet, MD worked with

Jumpengineers to developaprocess for converting two-dimensional images of

the heart into 3D-printed replicas for pre-surgical planning. Since the first

model that changed the course of a 9-month-old girl's surgery, we now have a

team of engineersat Jumpandthe University of Illinois College

of Engineeringworking to advancediagnostic effectivenessof imaging

tests aroundthe world.

HOW: IMPROVING UNDERSTANDING

Our engineers at

Jumphavecreateda

prototype program

to view3Dimagesof

heartsandother partsof

the human anatomy for

the HTC Vive, a virtual

reality headset.

Address Social Impacts to

Provide More forThosewith Less

HowcanOSFbest serve its most

disadvantaged populations?

The greatest health issue for some members of our

community is finding their next meal. When people face

daunting obstacles like hunger or homelessness, it’s hard

to focus on health until there’s a costly crisis. Innovation

here finds new ways to engage disadvantaged individuals

through new business models, care delivery, and / or

preventive care. Currently, many existing solutions

are available to only certain social classes. Innovation

here seeks to remove that barrier, providing effective

treatment to all who need care.

WHAT

Ourpopulation and their needs

Disadvantaged individuals—burdened by low income,

racial discrimination, language barriers, and other issues—

often struggle to get care until extreme situations result in

emergency visits. These situations are exacerbated by the

lack of affordable preventive care. OSF must understand this

population intimately and develop solutions that fit its unique

needs andcontext.

OF HOUSEHOLDS

OSF SERVES ARE

LOW-INCOME46%

22%OF OSF

HOUSEHOLDS

ARE BELOW THE

POVERTY LINE

50%of a community’s health is

attributed tosocial, economic, and

physical environment factors

1.4 MILLIONnon-profits working on independent

solutions to major social problems, often working at odds with one another and

increasing the perceived resources required to make meaningful progress.

SUPPORTING DATA

SUPPORTINGDATA

BY2020,THE65+ POPULATIONTHAT OSF

SERVES IS EXPECTED TO GROW

13.6%IN ALLREGIONS

Aging in Place (andwith Grace)

WHAT

Ourpopulation and their needs

The elderly are the fastest growing population that OSFserves,

yet where andhow they wish to spendtheir lives often takes

aback seat to budget, clinical, andcaregiver limitations.Their

families are often not effectively engaged in care decisions,

particularly end-of-life planning. This population needs new

options andmodels that fit into their lives, rather than asking

them to disrupt where and how they live.HowcanOSFempower elderly

patients and their caregivers?

Tapping into new technologies, communities, and services

can afford the elderly more flexibility and choice. For

example, distributed sensors in the home and analytics

can shift the focus from institution-based aging to

community-supported aging that largely happens in the

individual’s home. Innovation here avoids unnecessary

hospitalization of the elderly by providing them services

and tools to make the right choices for themselves. It will

transform how end-of-life planning, geriatrics, home care,

and assisted living are addressed and delivered.Many parts of the country—

especially counties in the rural

Midwest—are “aging in place”

because disproportionate

shares of young people have

movedelsewhere

of all people in a

nursinghomeare

there because of

social deficits, not

physical deficits

87%Of adults age 65+ want to stay in their current home

and community as they age

50%

SUPPORTINGDATA

RURAL COMMUNITIESCONTAIN 20%

OFTHE POPULATION BUT ONLY

ofpracticing

physicians9%

12% of pharmacists

Ourpopulation and their needs

The significant rural population OSF serves can struggle to

access care conveniently or effectively. Other populations,

like Millennials, want health care to fit their lives in ways other

generations never expected. Innovation here will make it

dramatically easier and more elegant for Mission Partners to

connect with their community, whenever and wherever they are.

of smartphone owners have

downloaded anapp specifically

to track or manage health

230,000doctor’s visits could be avoided

if patients 15+with sore throats

used ahomestrep test

2012-2013

50%market growth rate of at-home

diagnostics (e.g., heart rate

monitors,A1C test kits, HIVtests)

19%

Radical Access toCare

WHAT

HowcanOSFradically democratize access

to care, regardless of setting or context?

Radical Access includes care through mobile delivery,

community groups, and peer-to-peer relationships. It

seeks to increase care for the population, provide Mission

Partners more flexibility, and / or expand the footprint

of OSF in rural areas. Innovation here may also focus on

building communities that foster health care beyond the

hospital—at school, home, and work—making a healthy

community everyone’s priority. OSF will initially focus

efforts here on its rural population; as it makes progress,

it will consider expanding its focus to other segments.

We tackle these focus areas

with both core and

breakthrough innovationsInnovationcanbeasambitiousasreinventing how patients receive

care and as targeted as small refinements in the waiting room

experience. We needinnovationsboth largeandsmall to advance our

focus areas, so OSF Innovation categorizes innovation in to two

categories dependingon their levelof ambition.Thiscategorization

allows us to accurately provide the support that solutions or ideas

needto becomeareality.

WHAT

Developing breakthroughsand inventing

things for markets that don’t yet exist

• Most companiesarenot set upto exploreor commercialize

things that are newto the world, evenif the promise ishuge

• Involvesthe greatest amountof risk anddegreeof uncertainty

• Delivers the greatest returns when youhit it right

• Comprisesasmallernumberof initiatives driven by

focusedresources

BREAKTHROUGH: INVENTING THE NEW

Optimizing existing products and

services forexisting patients

• Whatwe feel most comfortable doing

• Most consistentandpredictable—we’re experts in the space

• Lower returns than transformational innovation

• Drivenwidely acrossOSFbyawide rangeof Mission Partners

CORE: IMPROVING THEKNOWN

B R E A K T H R O U G H

Developing concepts

and inventing things for

markets that don’t yet exist

WH

ERE

TO P

LAY

(M

AR

KET

S &

PA

TIEN

TS)

AD

JAC

ENT

EXIS

TIN

GN

EW

EXISTING ADJACENT NEW

A D J A CE N T

Expanding from existing business

into “new to the company” business

CO R E

Optimizing existing products, processes or

assets for existing customers

OSF Innovation Current Portfolio

WHAT

Developing breakthroughsand inventing

things for markets that don’t yet exist

• Most companiesarenot set upto exploreor commercialize

things that are newto the world, evenif the promise ishuge

• Involvesthe greatest amountof risk anddegreeof uncertainty

• Delivers the greatest returns when youhit it right

• Comprisesasmallernumberof initiatives driven by

focusedresources

BREAKTHROUGH: INVENTING THE NEW

Optimizing existing products and

services forexisting patients

• Whatwe feel most comfortable doing

• Most consistentandpredictable—we’re experts in the space

• Lower returns than transformational innovation

• Drivenwidely acrossOSFbyawide rangeof Mission Partners

CORE: IMPROVING THEKNOWN

MA

RK

ETS

& P

ATI

ENTS

AD

JAC

ENT

EXIS

TIN

GN

EW

EXISTING ADJACENT NEW

OSF Innovation

PartnershipsOSF Performance

Improvement

OSF Ventures OSF Healthcare

AnalyticsOSF Simulation

B R E A K T H R O U G H

Developing concepts

and inventing things for

markets that don’t yet exist

A D J A CE N T

Expanding from existing

business into “new to the

company” business

CO R E

Optimizing existing products,

processes or assets for

existing customers

75%

15%

10%

Core Innovation Optimizing existing products, processes or assets for existing customers

HOW

Department Specific Improvement Rapid Improvement realized by equipping front line managers with: tools, knowledge, experience to implement solutions, monitor effectiveness, assess need for change

Increasing capability for Continuous Improvement

TransformAssess Sustain

Entity Wide ImprovementDelivering operational results: business unit lead improvement initiatives designed to maximize operational performance

Ministry Wide ImprovementExecuting on Ministry strategy: highly coordinated, organizationally aligned ministry wide initiatives, designed to meet One OSF goals and key results

Lead

ersh

ip C

om

pet

ency

Org

aniz

atio

nal

Go

als

Cap

abili

ty t

o Im

pro

ve

Rep

ortin

g Imp

rovem

ent

Ensu

ring A

ccou

ntab

ility

High

Perform

ance O

rganizatio

n

Data AnalysisPerformance Improvement

Learning Series

Portfolio Management

Execution of Projects & Programs

Organizational Goals Monitoring Performance

to Target

Leveraging OSF’s PI Methodologies to support Continuous Improvement

LEAN6Sigma

Project ManagementRapid Improvement

Change Management

Continuous Improvement

Re-Assessment

Transforming health care to improve the lives of those we serve

Perf

orm

ance

Imp

rove

men

tC

ycle

Executive Sponsor

• Owns vision, directs integration, results

• Leads change

• Sets bold goals

Business Leader

• Project owner

• Removes barriers to implement and sustain

Process Owner

• Supports project team

• Responsible for implementation

• Sustains gains

PI Coach

• Supports and trains PI Specialists

• Provides guidance to leadership and project team

PI Specialist

• Full-time

• Facilitates teams

• Trains and coaches project team members

• Coaches/supports PI Leads

PI Lead

• Part-time on RIM(90 day) projects

• Applies continuous improvement methods in area of responsibility

Mission Partners

• Apply concepts to their job and work area

• Understand vision

Core InnovationOptimizing existing products, processes or assets for existing customers

HOW

Solution Summary• Implement EPIC module to standardize and have one

method to request, notify, and document patient movement.

• Set guidelines and limits for movements that generate idle time to reduce transporter is waiting.

• Document round trips as two patient movements instead of one.

• Develop House-wide patient movement policy with all changes from project.

Results• Solutions implemented except EPIC transport module:

improved from 25 minutes to 18 minutes in 6 months• Solution with EPIC transport module implemented

August 2016: Improvement from 18 minutes to 12 minutes

• Opportunity to improve patient movements.

Ivantage data showed that there was an excess of

FTEs compared to others in their benchmark;

despite the fact that SAMC has longer hours of

operation and more areas to serve.

• Goal: improve patient and staff satisfaction, provide

timely arrival to testing, discharge and admission

locations, and revise inefficient manual practices

prior to implementing the approved EPIC module

capital request.

• The baseline time to complete a transport

movement was 25 minutes prior to implementing

the standard manual practices and implementing

the EPIC module.

SAMCEPIC Transport Module Implementation

48%EFFICIENCY GAIN

Strategic Priority:

Patient Experience

Key Result:

HCAHPS Overall Rating

of the Hospital

Solution Summary• Standardized processes for after hours dispensing, after hours

compounding and after hours infusion were developed• Training plan including a competency assessment of aseptic

technique for nursing was developed and approved by entity CNOs

• Measurement plan to capture medications dispensed and or compounded after hours that are not available in patient care unit Pyxis was developed

• Assessment and standardization of medications needed within Pyxis for emergency access – this list was also adopted by the Central Region even though SFMC was out of scope

• Development of OSF critical notes to be added to Lippincott procedure IV solution preparation, adding medications to the container

Results• Reduce the number of non-Pyxis dispenses Ministry-wide

Have been reduced by 64% Ministry-wide

• Included entities: All OSF Entities with a non-24/7

pharmacy department (SFH, SEMC, SPMC, SJJWAMC,

SAHC, SMMC, SLMC, HFMC)

• Quick Win: Utilization of Pyxis global find function to

easily allow RNs to see where medication is located

without having to physically search multiple locations.

This enables faster delivery of medication to the patient.

One OSFPharmacy After Hours Dispensing Process RIM

64%MINISTRY-WIDE

Reduced the number

of non-Pyxis dispenses

Strategic Priority:

Patient Experience

Key Result:

HCAHPS Overall Rating

of the Hospital

SUPPORTINGDATA

HIGH RISK PATIENTS PRODUCE

$22MCOST THAN THOSE IDENTIFIED VIA

CURRENT HCC MODEL

Predicting the Future

HOW: INTEGRATING ANALYTICS

Improving the Lives of Those We Serve

What if we knew you were predisposed to be readmitted to the

hospital in less than 30-days and could put preventative solutions in

place for you before you left the hospital the first time? Through our

OSF Healthcare Analytics, we are working on predictive 30-day

Readmission models along with models for Sepsis, COPD,

Cardiovascular Bundles and more. We are advancing innovation

through data to ensure healthier communities.The dilemma is not about

understanding the population risk,

but identifying WHO is at risk

The rapid deployment of EPIC coupled with the strategic investments in Analytics, specifically data science/predictive modeling and data warehousing, have built an industry leading ecosystem for advanced analytics.

Risk stratification, whether through our Readmission Model, ACO Cost model or OSFMG Utilization model, allows us to categorize patients by risk in order to align resources. By doing so, we can most effectively manage a populations risk, while simultaneously maintain appropriate stewardship of our resources.

In bedside nurse

time was shifted

from data

collection from

the readmission

model back to

patient care

The OSF Utilization Model allows for a unified risk score for all

350,000+ medical group patients

$2M

Partnering for Innovation

OSF identifies partners with opportunities that will improve patient outcomes,

enhancepatient experience,andreduce the cost of health care. We believe in

not only investing financially, but also strategically through comprehensive

collaboration.

OSF Identifies Innovation Partners Through Relationships:

Weteam up with other innovators to

test solutions.

AVIA

OSF is a member of AVIA cohorts, which identifies start-ups that are addressing challenges relevant to providers. They select the most relevant start-ups and organize demos withproviders.

Plug n Play

A global innovation platform connecting startups to corporations, and invest in over 100 companies every year

MATTER

A Chicago-based incubator that allows start-ups to rent space, network with corporate partners, and seekpiloting opportunities.

HOW:PARTNERSHIPS

HOW:PARTNERSHIPS

Formal Innovation Partnerships

Upon completion of vetting partnership opportunities OSF may enter into a contracted

innovation partnership that may include one or more of the following actions:

• Usability Services -Utilizing testing refers to evaluating a product or service

by testing it with actual end users with the goal of identifying usability

problems, useful data and to determine end user satisfaction

• Clinical Trials -A branch of healthcare science that determines the safety

and effectiveness (efficacy) of medications, devices, diagnostic products

and treatment regimens intended for human use

• Pilots -A short term experiment designed to test logistics, prove value and

reveal deficiencies before large scale implementation

• Implementation -Partnerships that have resulted in successful pilots and or

previous implementations

OSF Partnership - Overview

Home Monitoring EquipmentFocus Area: Aging in PlaceStatus: Clinical ResearchSponsor: Dr. ClemsonKick off: 10/1/16Scope: Currently the home monitoring vendor for Home Care Ministry wide, currently conducting 50 patient research study with CFH in Central Region

Genetic Screening solution for Breast and Colon CancerFocus Area: Radical AccessStatus: PilotSponsor: Dr. NoraKick off: 3/1/16Scope: Completed 14 month clinical trail in Central Region in November of 2016, began implementation in Northern Region in February of 2017

Provides tools and resources for expecting moms, kick and weight trackers, class registration and cross marketingFocus Area: Radical AccessStatus: ImplementationSponsor: Susan MilfordKick off: 4/21/17Scope: Implementing Northern Region in May, Central Region in June, Eastern Region in July

Care Management application that coordinates care to reduce costs, improve outcomes, and drive a 5-star patient experienceFocus Area: Radical AccessStatus: PilotSponsor: Hoa CooperKick off: 1/15/17Scope: Began enrolling spine surgery patients in Central Region in January, expanding to hip and knee replacement with six surgeons in Peoria and Ottawa in May of 2017

Patient Wisdom efficiently collects, curates, segments, and shares patient stories to improve the experience and delivery of careFocus Area: Social Determinants Status: PilotSponsor: Dr. TilleryKick off: 3/15/17Scope: Piloting with Streator Community

Digital displays in waiting rooms and exam rooms deliver hyper-targeted information to patients at the point of care, during the most actionable moments of their treatmentFocus Area: Radical AccessStatus: PilotSponsor: Susan MilfordKick off: 4/7/17Scope: Implementing in all Neuro and Cardiac offices in Central Region as well as all Care Transformation offices in Primary Care

OSF Partnership - Overview

Procedural Time out applicationFocus Area: Radical AccessStatus: Clinical ResearchSponsor: Dr. PearlKick off: 10/1/16Scope: Conducting 100 patient clinical trial in with Pediatric OR patients at SFMC.

Behavioral Health tele health providerFocus Area: Radical AccessStatus: PilotSponsor: Cheryl CroweKick off: 7/1/16Scope: Began pilot with Care Transformation practices, expanding to Ottawa in March 2017

SilverCloud is used by health systems and care organizations to provide clients with easy and immediate access to evidence-based and supported therapeutic solutionsFocus Area: Radical AccessStatus: ImplementationSponsor: Cheryl CroweKick off: 4/3/17Scope: Piloting with Health Coaches and Primary Care Behaviorists in all Regions

Tablet real-time survey toolFocus Area: Social DeterminantsStatus: PilotSponsor: Lori WiegandKick off: 8/28/15Scope: Being used to collect patient and provider feedback in Care Transformation Offices

Patient Decision Making Tool using guidance from the best evidence to fit a patient’s unique clinical situation and treatment goalsFocus Area: Aging in PlaceStatus: PilotSponsor: Dr. SawickiKick off: 4/10/17Scope: Piloting with Advance Care Planning Coordinators in all Regions

IRIS application puts social services on a single technology platform that integrates with healthcare system care management Focus Area: Social DeterminantsStatus: PilotSponsor: Ken BeutkeKick off: TBDScope: Piloting with Streator Community

Investing in Innovation

OSFVentures

OSF Ventures invests financially and operationally in

opportunities that will improve patient outcomes, enhance

patient experience, and reduce the cost of health care. We

believe in not only investing financially, but also

strategically through comprehensive collaboration.

Value Proposition to OSF

• Identification of solutions to reduce cost or achieve other ministry

objectives.

• Access to emerging technologies to improve patient service.

• Opportunity to collaborate and provide meaningful input during the

product development phase.

• Opportunity to participate in pilots or clinical trials, which can result in

recognition through publications.

• Ability to benefit financially and operationally.

OSF Ventures Dashboard

HOW: INVESTING IN INNOVATION

Venture Opportunities by Category Venture Opportunities by Status

7%

6%

83%

4%

Pre-Pipeline

Pipeline

Not invested

Invested

195

83

16412

12

23

45 Health InformationTechnology

Delivery Solutions

Bio Technology

Other

Therapeutics

Diagnostics

Medical Device

OSF VenturesPipeline Companies

HOW:PARTNERSHIPS

Company Description

Biome Analytics Healthcare Analytics

Diagnostic Photonics Intraoperative Tumor Detection Imaging System

HealthLoop Pre-admission/Post-discharge Patient Engagement Tool

Innoblative Designs, Inc. Intraoperative RF Ablation Medical Device

Navigate Cardiac Structures, Inc. Transcatheter Mitral and Tricuspid Valve Replacement Technology

Orpheus Medical Clinical Media Management Solution

Patient Wisdom Patient Engagement Tool

Prenosis Sepsis Diagnostic Blood Testing Solution

Regroup Therapy Behavioral Health Patient Engagement Tool

WiserCare Shared Decision Making Patient Engagement Tool

OSF Ventures Deal Flow Process

Intake

Companies across different healthcare verticals are introduced to

OSF Ventures through;

Incubators/Accelerators

Portfolio CompaniesOSF Internal

Syndicate PartnersWeb Presence

Investment BankersVenture Conferences

The OSF Ventures team determines if technology fits into the following

categories:

-Medical Device-Diagnostics -Therapeutic

-Health IT-Healthcare Analytics

Vetting

High level overview to determine if technology supports the OSF

Ventures objectives and creates value for OSF Healthcare System.

Ventures Team reviews company’s information with input from our

Innovation Fellow and Innovation Partnerships team.

Subject Matter Experts (SME’s) are identified who can provide high level feedback on technologies that pass

initial vetting.

Pre-Pipeline

Companies that have passed the vetting stage enter into the pre-

pipeline.

OSF Ventures team reaches out to SME’s and provides them with a short

questionnaire seeking input on the technology.

OSF Ventures team initiates communication with company’s

management team.

Pipeline

Companies that are viewed favorably by SMEs and pass an introductory call

enter the pipeline.

OSF Ventures team engages with SMEs for more in-depth feedback.

OSF Ventures conducts business diligence.

Begin to explore potential opportunities for collaboration within

the system.

What

How

OSF Ventures Deal Flow Process

Investment Recommendation

Summary of clinical and business diligence.

OSF Ventures submits investment summary and investment

recommendation to the Venture Committee

On-site company presentations to the committee.

Final Approval

Final Committee Approval

Final concerns resolved and vote taken.

OSF Ventures conveys approval to the company and initiates

legal diligence.

Investment

OSF receives equity ownership for cash.

Investment made when legal diligence completed.

Portfolio Management

Post investment management and governance.

OSF Ventures tracks performance based on board

level info and attendance.

What

How

Active Business Diligence

Pipeline Stage

OSF Venture Team Diligence Encompasses:• Corporate History Review• Management Team Evaluation• Business Model Analysis • Clinical SME Analysis • Market Analysis• Financial Analysis• Product Research• Competition Assessment • Manufacturing and Sales Strategy Review • Regulatory Pathway Review (assessing FDA regulatory requirements

prior to market-entry) • Reimbursement Strategy Analysis (assessing revenue model and billing

code structure) • Syndicate Partner Analysis (research on potential co-investors)• Deal Term Analysis (evaluating investment terms and deal structure)

The OSF Ventures Portfolio

OSF Ventures is an LP investor in Ascension Ventures Fund IV - an investment arm of Ascension Health Alliance headquartered in Clayton, Missouri; primarily focused on investing into the healthcare sector

Technology accelerator working exclusively in the healthcare space based in Chicago

Medical device used by interventional radiologists to streamline treatment for severe ureteral obstruction, founded in Peoria, IL and now based in Mountain View, CA

Wireless heart failure monitoring solution for those suffering from Class III CHF, located in Woodridge, IL

Data warehousing company based in Salt Lake City

Predictive analytics modeling company founded by the Parkland Hospital System in Dallas

Therapeutic for stroke victims combining iron micro-beads with the current drug (tpa) and magnet technology, based in St. Louis

33

Automating the Revenue Cycle via Machine Learning

The Machine Learning application involves the advanced use of computational analytics to predict the most effective resolution tasks for an exception (e.g. credits, denials), based upon OSF’s and Industry’s experience … and then automate those tasks wherever possible.

Consistent with other industries that currently use Machine Learning and automation (e.g. driverless cars, manufacturing floors, radiology readings, auto-fill texting), the computer can process thousands of variables in seconds to determine the most successful resolution path (e.g. 95%+ confidence).

Analyze thousands of resolved OSF accounts and, using Machine Learning, determine the resolution steps which resulting in the quickest and highest payments. Thus begins the transition from Craft to Standardize to Systematize to Automate.

Example: One Crowe client had 21,342 Managed Medicaid Request for Information denials. Via Machine Learning, it was determined that one resolution path, executed for 688 of these accounts, had a payment success rate of 99.7%. The rest of the accounts had a 58.7% success rate on average.

“The result is an expansive and distributed source of truth — built not from trust, but through cryptographically enforced consensus. The information stored can be anything: financial transactions (à la bitcoin), land-title deeds, personal identity, intellectual property, even “smart contracts” — computer code that executes when certain conditions are met. Yet blockchain’s most important attribute is its immutability: once something has been added, it is permanent —stored across thousands of computers, cryptographically locked in history.”

Blockchain…

Source: Gordon, et al, Blockchain in Health Care: Decoding the Hype, http://catalyst.nejm.org/decoding-blockchain-technology-health/

Blockchain in Healthcare•Clinical data sharing. Advance directives, genetic studies, allergies, problem lists, imaging studies, and pathology reports. Alternately, instead of storing actual patient data, blockchain could be used to store access controls — like who a patient has authorized to see their health data —even if the clinical data itself is stored by the EHR.•Public health. A shared, immutable stream of de-identified patient information could more readily identify pandemics, independent of governmental bodies currently aggregating this data•Research and clinical trials. Distributing patient consent or trial results could foster data sharing….and analysis•Administrative and financial information. Eligibility and claims processing workflows could…decrease transactional costs.•Patient and provider identity. National (or international) patient or provider identities could be secured in the blockchain, providing the basis for health data portability and security.•Patient-generated data. Personal health devices, “wearables,” “Internet of Things” (IOT) devices, and patient-reported outcomes are just some examples of patient-generated data that could leverage the blockchain for security and sharing.

“Most of these use cases are top-down: data used and generated on behalf of patients. But perhaps the greatest potential of blockchain technology is the empowering of patients to own and gather their own data. In many ways, the promise of blockchain lies outside the current health information technology framework — directly challenging the siloed, centralized data stores that dominate health care data today.”

Source: Gordon, et al, Blockchain in Health Care: Decoding the Hype, http://catalyst.nejm.org/decoding-blockchain-technology-health/

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OSF HealthCare