2003 Aziridine derivatives

Aziridine derivativesR 0040 Intermolecular Alkyl Radical Addition to Methyl 2-(2,6-Dichlorophenyl)-

-2H-azirine-3-carboxylate. — Addition of alkyl radicals to the azirine (I) proceeds in good yields and high stereoselectivity when alkyl iodides (II) are used. In other cases such as 4-chloroiodobenzene, (2-iodoethyl)benzene, n-hexyl, n-octyl and allyl iodide [cf. examples (V)], the rate of iodine atom transfer is to slow resulting in formation of (IIIa) from (I) and triethylborane. — (ALVES, M. J.; FORTES, G.; GUIMARAES, E.; LEMOS*, A.; Synlett 2003, 10, 1403-1406; Dep. Quim. Bioquim., Fac. Cienc. Tecnol., Univ. Algarve, P-8000 Faro, Port.; Eng.) — Mais

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