INTRAVENOUS OZONE THERAPY

The Direct IV Method and Anti-AgingDr. Howard F. Robins, D.P.M.,D.A.B.P.E.,Member, A.A.O., Member, I.A.O.H.D., H. M. Ozone Practitioners Organization of Malaysia 200 West 57th Street, New York, New York, 10019(O)212-581-0101 (C) 516-967-1009

What if there was a safe, effective and proven treatment for just about every disease?

What if it had been successfully used for over 70 years all over the world?

What if there were hundreds of medical papers written about it?

What if there were thousands of doctors, clinics and hospitals worldwide using this therapy everyday?

What if hundreds of thousands of patients with AIDS, Hepatitis C, Arthritis ,Herpes, MS and a host of many other diseases used this therapy with success?

You would have heard about it, right?

Well, guess what? There is such a therapy but because of the blackout in the news you may not know it exists and you don’t know it works safely?

WHY?

$$$$ IT IS LOW COST $$$$$$$$ IT IS NOT PATENTABLE $$$$THUS, NO MONEY IN IT FOR THE PHARMACEUTICAL COMPANIES!

FOLLOW THE MONEY TRAIL!

When ozone enters the body it acts like “glue” to toxins, toxic metals and harmful free radicles allowing the body to remove them.

Simply, being electron deficient, it steals an electron from bacteria, virus, fungus, yeast and mold cells destroying them. Organisms cannot mutate into a strain that cannot be destroyed. Cuts through bio-film.

It has many benefits to the blood and circulation and energy production.

In concentrations of 50-55mcg’s (gamma) it causes the greatest increase in production of alpha and beta interferon; interleukin-2,6,7,8 and TNF

What does ozone do?

Major AutoHemotherapy(with/without Hyperbaric) (MAH)(45,000)

Direct Intravenous Ozone (DIV)(140,000)

EBOO/ Alif 1 EBOO SAFE (Simple Access Fluid Extraction)/ AquaphersisMost Effective

Methods of Administration

Glucose-6-Phosphate-Dehydrogenase Insufficiency

Ozone Allergy Recent Myocardial Infarction Active Hyperthyroidism Thrombocytopenia Pregnancy

Contraindications

In my practice only two patients in over 140,000+ DIV therapies developed a “temporary rash” within 30 minutes of a treatment, two treatments in a row after 30-40 treatments!

Jacobs,M.T., 1982, Untersuchung uber Zwischenfalle und typische Komplikationen in der Ozon-Sauerstoff-Therapie, OzoNachrichten 1:5 Study in Germany, 644 therapists surveyed, 384,775 patients, 5,579,238 treatments (over two years),only 40 cases of adverse reactions, a rate of .0007%!

Adverse Reactions

Direct IV puts an oxygen/ozone gas mixture directly into the veins at a set concentration.

Concentration used is from 14 to 55 mcg/cc (gamma) (1% O3 @ 14mcg’s to 3.95% @ 55mcg’s)

Volume of gas delivered is from 5 to 240cc at a rate of 1cc every 5 seconds or slower.

Creates high levels of ROS and LOP’s in blood

DIRECT IV

“There have been deaths from DIV”“It causes oxygen lung embolisms”“It creates harmful free radicals”“It damages veins”

Medical “Urban Myth”

Hair and nails grow longer, stronger, healthier and faster.

Skin becomes healthy. Fall asleep easier, sleep better and need less

sleep. More energy all day long. Increases blood circulation and tissue

oxygenation. Greater endurance during athletic training. SLOWS THE AGING PROCESS

DOWN!

Side Effects

Precise dosage Less medical waste; simple syringes used Stimulates Increase of anti-oxident enzymes in healthy cells Removes unwanted antibodies ( sero-conversion) and harmful free

radicals from blood Small (27g) needles used, veins saved Allows for use of smaller veins, more patients eligible No need for Heparin Creates LOP’s and ROS’s in blood in large amounts Stimulates the body to make large amounts of Interferon and Interlukens

(2,6,7,8 and TNF) Crosses blood brain barrier Chelates toxic metals off nerve tissue Removes plaque from arteries Takes only 1 to 12 minutes to complete Allows two treatments per day/6 days a week Lower cost to patient with faster results Cuts through bio-film

Benefits of Direct IV over MAH

Blood is treated ex vivo similar to a classical dialysis system with oxygen-ozone flowing in the opposite direction and the blood being filtered through a special filter system

Takes about one-two hours Ozonates all the blood several times per

session NO ozone enters the body Does react with gluathione in the blood

creating ROS’s and LOP’s Performed only once per weekEBOO- EXTRACORPOREAL

BLOOD OXYGENATION & OZONATION

Many functions including elimination of excess body fluid (edema)

Sterilization of entire blood supply several times per hour

Takes 1 ½ hours, done once a week Cleanses entire blood supply of ALL impurities

including cholesterol Removes all waste as well as any off gassing in an

enclosed system Little to no ozone enters the body Must have good veins or PIC line Reduces size of heart while increasing cardiac

output

Alif 1 EBOO SAFE by CHF Solutions, Inc.

EBOO

Rectal Insuflation Vaginal Insuflation Prolotherapy-Prolozone Drinking ozonated water Direct injections into tissues Ozone sauna-vinyl exercise suit

WARNING!NEVER INHALE OZONE IN HIGH

CONCENTRATIONOther theraputic methods of using Ozone

All viral, bacterial and fungal diseases and infections:

Measles; Herpes (all forms); Lyme; AIDS; Acne; Hepatitis A, B, C; Gangrene; Flu; Rhinovirus;Candidiasis; Tinea; C. dif.; E. coli; Krohn’s; Pneumonia; Polio; Warts; Stealth viruses (echovirus); Shingles (post-herpetic pain); Protozoal infections of all kinds. Bells palsy; MS; ALS (Viral?) Some Diseases-

ConditionsTreated with Ozone

All auto-immune diseases: RA; Lupus; Scleroderma RSD/CRPS Burns Parkinson’s; Alzheimer disease ASO; Atherosclerosis Diabetic neuropathy; retinopathy; ulcers Allergies/asthma Glaucoma; Macular degeneration; Conjuctivitis

(all forms) Anything with “itis” at the end of it Psoriasis; most every skin conditions

Some Diseases-ConditionsTreated with Ozone

STUDIES?STUDIES?SHOW ME SOME STUDIES!!!

Probl Tuberk Bolezn Legk. 2009;(3):28-33.

[Ozone therapy for protracted pneumonias].[Article in Russian]Belianin II, Shmelev EI.Ozone therapy for protracted pneumonias substantially enhances the efficiency of antibiotic treatment.

PubMed- Examples of the Scientific Study of Ozone Therapy

Patol Fiziol Eksp Ter. 2008 Oct-Dec;(4):23-5.[Pathophysiological aspects of endotoxicosis complicated with purulent infection of the foot and correction of endotoxicosis with conventional treatment and with application of ozonized physiological solution in patients suffering from diabetes mellitus].[Article in Russian]Gazin IK.While the conventional therapy reduces endogenous intoxication, intensity of lipid peroxidation, ozonotherapy produces a prompt and effective decrease in pathological activity of lipid peroxidation, regulates a dynamic balance between pro- and antioxidant systems of the human body and, finally, reduces endotoxicosis severity in diabetic patients.

J Laryngol Otol. 2009 Jan;123(1):54-60. Epub 2008 Oct 17.

Randomised, double-blinded, placebo-controlled, clinical trial of ozone therapy as treatment of sudden sensorineural hearing loss.Ragab A, Shreef E, Behiry E, Zalat S, Noaman M.Department of ORL Head and Neck Surgery, Menofia University Hospital, EgyptOzone therapy is a significant modality for treatment of sudden sensorineural hearing loss; no complications were observed

[Combined treatment including ozonotherapy of patients with viral hepatitis ].

[Article in Russian]Chernyshev AL, Filimonov RM, Karasev AV, Neronov VA, Maksimov VA.Vopr Kurortol Fizioter Lech Fiz Kult. 2008 May-Jun;(3):19-22.…with the purpose to correct of disturbances of hepatic exocrine function in patients with viral hepatitis and to prevent stone formation, it is reasonable to use together with antiviral therapy also intravenous injection of ozonated physiological solution and preparations of ursodeoxycholic acid.

Vestn Ross Akad Med Nauk. 2008;(4):27-34.

[Conservative methods in the therapy of male sterility. Critical analysis].[Article in Russian]Artiukhin AAAfter 2-3 courses (with intervals of 3 months) positive dynamics was observed in almost 70% cases. Thus, general ozonotherapy should be considered as one of effective technologies of treatment in patients with male sterility.

Nan Fang Yi Ke Da Xue Xue Bao. 2007 Mar;27(3):384-6.

[Percutaneous intradiscal oxygen-ozone injection for lumbar disc herniation: no need of perioperative antibiotic prophylaxis].[Article in Chinese]Wei CJ, Li YH, Chen Y, Wang JY, Zeng QL, Zhao JB, Mei QL.Department of Interventional Radiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. wcjun1999 @163.comProphylaxis antibiotics is not necessary during the perioperative period of percutaneous intradiscal ozone injection for lumbar disc herniation.

Vopr Kurortol Fizioter Lech Fiz Kult. 2006 Nov-Dec;(6):34-7.

[Ozone therapy in gastroduodenal pathology associated with Helicobacter pylori]Fedorov AA, Gromov AS, Sapronenok SV, Kurochkin VIu, Zhernakova ZM.All the techniques of ozone therapy proved effective in relation to regress of clinical symptoms, regeneration processes, eradication of Helicobacter pylori, but the combined regimen was the best.

J Craniofac Surg. 2006 Nov;17(6):1080-3.New therapeutic protocol in the treatment of avascular necrosis of the jaws.Agrillo A, Petrucci MT, Tedaldi M, Mustazza MC, Marino SM, Gallucci C, Iannetti G.Department of Maxillo-Facial Surgery, University of Rome "La Sapienza," Policlinico Umberto I, Rome, Italy.An analysis of the international medical literature shows that surgical treatment of the necrotic jaws in patients treated with bisphosphonates has proven to be ineffective in stopping the pathological process. The use of hyperbaric oxygen and antibiotics are not effective, either. The authors have developed a new protocol for the management of these lesions. Compared with other therapeutic choices, this protocol has introduced the use of ozone therapy as therapeutic support.

Int J Artif Organs. 2005 Oct;28(10):1039-50.

Extracorporeal blood oxygenation and ozonation (EBOO): a controlled trial in patients with peripheral artery disease.Di Paolo N, Bocci V, Salvo DP, Palasciano G, Biagioli M, Meini S, Galli F, Ciari I, Maccari F, Cappelletti F, Di Paolo M, Gaggiotti E.Nephrology and Dialysis Department, University Hospital of Siena, Siena—ItalyEBOO was much more effective than prostacyclin for treating skin lesions in PAD patients and also had a positive effect on patient general condition without any apparent change in arterial circulation. This suggests other mechanisms of action of EBOO.

Med Sci Monit. 2002 Jul;8(7):CR520-5.Ozone therapy and the activity of selected lysosomal enzymes in blood serum of patients with lower limb ischaemia associated with obliterative atheromatosis.Tafil-Klawe M, Woźniak A, Drewa T, Ponikowska I, Drewa J, Drewa G, Włodarczyk K, Olszewska D, Klawe J, Kozłowska R.Department of Physiology, L. Rydygier Medical University in Bydgoszcz, PolandOzone therapy administered by intravenous infusions and aerosol oxygen-ozone baths of lower extremities yields much better therapeutic results in comparison with classical balneology.

Zh Nevrol Psikhiatr Im S S Korsakova. 2000;100(11):35-7.

[Ozone therapy of migraine].[Article in Russian]Kotov SA.In 58% of the patients the attacks were absent during 3-5 months after ozone therapy; less intensity of headache was observed after their relapse. Improvements in the patients coincides with changes in biochemical parameters.

Panminerva Med. 1995 Sep;37(3):129-32.

Effects of ozonized autohaemotherapy on human hair cycle.Riva Sanseverino E, Castellacci P, Misciali C, Borrello P, Venturo N.Institute of Human Physiology, University of Bologna, Italy.The dosage of ozone was 2500-3000 micrograms for each treatment, one cycle consisting of 16 treatments. Results showed a marked improvement of the hair cycle.

Br J Biomed Sci. 2007;64(1):44-9.The case Department of Physiology, University of Siena, via Moro 2, 53100, Siena, ItalOzone is a very reactive gas that is toxic to the respiratory system. However, under controlled conditions, it can be therapeutically useful in several human diseases. An unfavourable combination of factors (ozone is one of the worst troposphere pollutants) and past misuse have led to misgivings about ozonetherapy. However, basic and clinical work developed over the past 10 years has clarified the fundamental mechanisms of action of ozone in biology and medicine. Interestingly, judicious doses of ozone dissolved in blood trigger a cascade of well-defined chemical compounds acting on multiple cellular targets according to well-known molecular, biochemical and pharmacological pathways. Ozonetherapy is proving to be very useful in age-related macular degeneration, ischaemic and infectious diseases, and in wound healing disorders, where conventional medicine has failed. Critical evaluation of the potential therapeutic utility of this simple, inexpensive medical application by national and international health authorities is warranted and may lead to clinical benefit for a large proportion of the world's population.

Mediators Inflamm. 2004 Feb;13(1):3-11.Ozone as Janus: this controversial gas can be either toxic or medically useful.Bocci V.Department of Physiology, University of Siena, Italy.Ozone is an intrinsically toxic gas and its hazardous employment has led to a poor consideration of ozone therapy. The aim of this review is to indicate that a wrong dogma and several misconceptions thwart progress: in reality, properly performed ozone therapy, carried out by expert physicians, can be very useful when orthodox medicine appears inadequate. The unbelievable versatility of ozone therapy is due to the cascade of ozone-derived compounds able to act on several targets leading to a multifactorial correction of a pathological state. During the past decade, contrary to all expectations, it has been demonstrated that the judicious application of ozone in chronic infectious diseases, vasculopathies, orthopedics and even dentistry has yielded such striking results that it is deplorable that the medical establishment continues to ignore ozone therapy

Aging

As people age, their bodies bodies extract oxygen and transport it to cells LESS efficiently.

The cumulative effect of this lack of O2 is:

• A decrease in the flow of nutrients to the cells• Impairment of creation of necessary cell energy• Impairment of necessary cellular chemical

reactions• Cells die prematurely• Appearance of disease

Aging

By inactivating and/or destroying all viruses, bacteria, fungus, yeast and mold

By eliminating all harmful free radicals By eliminating all toxic metals By destroying all tumors By increasing oxygenation of cells and

creating necessary cellular energy

Anti-Aging Benefits: Reduces “STRESS” on the Body

Clumping of Red Blood cells is reduced or eliminated

Increase flexibility of Red Blood cells Makes Red Blood cells rounder Increases Oxygen carrying ability Oxygenation of tissues increases as the

arterial partial pressure increases Viscosity of blood decreases Oxidizes the plaque in arteries

Anti-Aging Benefits: Benefits to Circulation

Causes increase in Red Blood cell glycolysis rate leading to stimulation of 2,3-diphosphoglycerate

This shifts the oxyhemoglobin disassociation curve to the right

Which leads to increase in amount of O2

released to cells

Anti-Aging Benefits:Stimulates O2

Metabolism

Ozone stimulates the production of anti-oxidant enzymes: Glutathione peroxidase, Superoxide desmutase, Catalase and Reductase which:

• Protect healthy cells from damage by ozone

• Acts as free radical scavengers reducing stress

Ozone activates the Krebs Cycle by enhancing oxidative decarboxylation of pyruvate thus stimulating production of ATP’sAnti-Aging Benefits:

Cell protection and Energy production

Ozone reacts with polyunsaturated fatty acids of the lipid layer in cellular membranes forming various peroxides (ROS’s)

Lipid Peroxidation: One of the two main processes whereby one mole of Ozone and one mole of an olefin (particularly arachidonic acid present in plasma triglycerides) create one mole of H2O2 and two moles of aldehyde (Pryor et. al., 1995)

This creates a number of different aldheydes known as Lipid Oxidation Products (LOP’s)

Most of Ozone’s reactions/benefits are due to the ROS’s and LOP’s which are created instantly as ozone dissolves in the lymph in blood

FORMATION OF ROS’S and LOP’s

Cells need energy to stay alive and perform their purpose

Healthy cells make energy via the Krebs Cycle They need oxygen and nutrients to make energy They need a delivery system to bring it They need a waste removal system

“OZONE’S BENFITS DELIVERS ALL OF THE ABOVE EXTENDING CELL LIFE AND FUNCTION THUS RETARDING THE AGING PROCESS!”Why this is so

Important to Anti-Aging

Aging is a necessary process.

The “trick” is to GROW OLD AND BE WELL and to be able to function on a high level.

THIS IS WHAT CAREFULLY PERFORMED OZONE THERAPY CAN

HELP DELIVER!

When you combine the cleansing, detoxification and immune boosting benefits of Intravenous Ozone Therapy, along with a program of healthy cardiovascular exercise and healthy nutrition, it is possible to significantly slow the aging process.

IN SUMMARY

“When one considers the alternative to growing old…”

THANK YOU FOR YOUR KIND ATTENTION!

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