introducing connected health cities

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NHSA, HEALTH NORTH AND CONNECTED HEALTH CITIES Dr Hakim Yadi, NHSA, Chief Executive Officer [email protected]

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NHSA, HEALTH NORTH AND CONNECTED HEALTH CITIES

Dr Hakim Yadi, NHSA, Chief Executive Officer

[email protected]

• Health Science Scotland: Front door for Scotland - a partnership of medical universities and their associated NHS Health Boards

• Northern Health Science Alliance: Front door for the North - 8 Universities / 8 NHS Trusts across the North of England (Liverpool, Manchester, Leeds, Sheffield, Newcastle, Durham, Lancaster, York / Hull)

• Invest Northern Ireland :Front door for Ireland - a partnership of medical universities, NHS and government

• MedCity: Front door for London - The three London Academic Health Science Centres

• Life Sciences Hub Wales: Nerve centre of a vibrant and prosperous Welsh Life Sciences eco-system

The UK life and health science clusters

To maximize the impact of the health science research and to provide a go-to

center for healthcare companies we have created the Northern Health Science

Alliance (NHSA), a collaboration across eight of England's great cities across a

population of 15m people.

A functioning health partnership for the North of England

Promote the combined value of the NHSA members

Act as a front door for the North’s Health Science Research

Work with industry to secure private sector R&D in the North

Work with research funders to secure greater public sector investment in the North

Work with members to maximize the impact of their research and service reform for the health of the North & UK

What we do

The North’s Research Strengths

Precision Medicine Population / Digital Health Healthy Ageing

Research Themes

eHEALTH & DATA ANALYTICSCLINICAL TRIALS & Health Economics

The Health Science Ecosystem in the Northern Powerhouse has deep expertise in Precision Medicine, Healthy Ageing and Population Health. This is underpinned by world leading clinical trials infrastructure, health economics and health informatics and eHealth.

Digital Health approaches and technologies are deployed across all research themes.

• Two Precision Medicine Catapults • Four Genomic England Centres • Two NIHR Diagnostic Evidence Cooperatives

(Leeds / Newcastle)• Two MRC / EPSRC Pathology Nodes• New Medicines Technology Catapult• Two MRC Single Cell Genomic Centres• The UK AMR Centre at Alderley Park• Cancer Research UK Manchester Institute• Cancer Research UK Leeds Centre• Cancer Research UK Newcastle Centre• Astbury Centre (Leeds)

• National Centre for Ageing Science & Innovation in Newcastle

• MRC Arthritis UK Centre for Integrative Musculoskeletal Ageing

• NIHR Newcastle Biomedical Research Centre in Ageing & Chronic Disease

• Alder Hey Children’s Hospital• York Neuroimaging Centre (YNiC)• Centre for Hyperpolarisation in Magnetic

Resonance (CHyM)• SITraN in Sheffield • Centre for Ageing Research (Lancaster)

• NIHR funded centres for Public Health research

• ESRC Centre for Translational Research in Public Health

• Institute of Infection & Global Health, University of Liverpool

• Well North• Three NHS England Test Beds• Liverpool John Moores University's

Research Institute for Sport and Exercise Sciences (RISES)

• CATCH in Sheffield

• NIHR Clinical Research Networks • Several Clinical Research Facilities, three in Manchester alone • MRC Network of Hubs for Trials Methodology Research• Sheffield School for Health Related Research • York Health Economics

• NWeHealth FARSITE trials recruitment tool• MRC eHerc, Farr Institute, NorthWest eHealth at Manchester • MRC Medical Bioinformatics Centre in Leeds• EPSRC Postgraduate Centre for Cloud Computing in Newcastle • Sci-Tech Daresbury and The Hartree Centre• eHealth SME cluster (Liverpool City Region)• Connected Health Cities• CHICAS, School of Health and Medicine.

Health Data Science

• Sci-Tech Daresbury • MRC eHerc • Farr Institute in Manchester • NorthWest eHealth • Leeds Institute of Data Analytics • EPSRC Postgraduate Centre for Cloud

Computing in Newcastle • National Smart Data Institute in

Newcastle• The Insigneo Institute for in silico

Medicine in Sheffield • NHS Digital (HSCIC)

The North of England has a critical mass of data science expertise and know-how, with government and research council investment across NHSA members.

Our challenge in health and equality

North West78.0

Yorkshire and Humber78.5

South West80.1

South East80.4

London80.0

East of England80.3

West Midlands78.8

East Midlands79.3

Wales

North East78.0

Boundaries of Government Office Regions in Northern and Southern England ShowingNorth to South Gradient in Life Expectancy at Birth 2011-2013 (source: ONS)

Male Life Expectancy at birth 2011-2013

North West81.8

Yorkshire and Humber82.2

South West83.8

South East83.9

London84.1

East of England83.8

West Midlands82.8

East Midlands83.0

Wales

North East81.7

Female Life Expectancy at birth 2011-13

COPD

Liver Cancer

LungCancer

Heart Disease

Our challenge in health and equality

Health North

New models of care

Oct 2014: NHSA White Paper presented to government.

• Health Data• Precision Medicine • Population Health

Health North

New models of care

Oct 2014: NHSA White Paper presented to government.

Jan 2015: NHSA round table with PM, CX and George

Freeeman.

• Health Data Analytics Centre• Precision Medicine Academy • Connected Health Cities

Health North: Connected Health Cities

New models of care

March 2015: Health North CHC announcement

Oct 2014: NHSA White Paper presented to government.

Jan 2015: NHSA round table with PM, CX and George

Freeeman.

Health North: Connected Health Cities

New models of care

Nov 2015: Grant Award

Letter

Jan – May 2016: Project set up

March 2015: Health North CHC announcement

Jan 2016: Official

project start

Oct 2014: NHSA White Paper presented to government.

Jan 2015: NHSA round table with PM, CX and George

Freeeman.

New understanding and models of care

New models of care

Data

Public sectorencounters

Services

Targetedby need

TargetingTools

Ark

Involved CitizensProblem OwnersData Managers

Public Health AnalystsCare Service Analysts

StatisticiansInformaticians

Social ScientistsHealth Economists

Health Service Researchers

Communications Experts

Service Planning

and PolicyInsights

SME Global Corp.

Which services and how?

Spin-in/out Laboratory

Farr Institute & NIHR Centres

Connected Health Cities

2015: Dilute, Duplicated Data Processing 2020: Ark Integrated Data Processing

NHS Commissioning

Research and Innovation

Public Health Intelligence

Social Care Management

RawData

NHS Quality Intelligence

Extract, clean, describe x 5

One size fits all

Ark

Public Involvement

NHS Commissioning

NHS Quality Intelligence

Public Health Intelligence

Social Care Management

Self-care and Personal Health

RawData

Extract, clean, describe x 1

CombinatorialResearch and Innovation

Literature

Policies

Literature

Policies

Targeting System

TransparentInterface with

Industry

Economies of Scale

De-identified Records

IdentifiedRecords

StudyProtocol

/Assessment

StudyRecruit

ClinicianResearcher

Commons of Metadata and Information Governance (Clinical & Research)

Clinical Care

Patient

Research Safe Haven

Encrypted (SHA1 & AES256);Certified (ISO 27001)

City 1

City 3

City 2

City 4

Linkable Data Providers

Research Objects

RAPID REPLICATION• Research protocol• Codes for the data• Statistical scripts• Results in progress• Draft manuscript• Slides etc.

Cities learning from one another

Learning Health Systems

Combining Health Data Uses to Ignite Health System Learning. Ainsworth and BuchanMethods of Information in MedicineIssue:2015 (Vol. 54): Issue 6 2015Pages:479-487

NHSA CHC Therapeutic Areas / Care pathways: North West Coast Connected Health Cities• Alcohol misuse• Unplanned Care

Greater Manchester • Building rapid interventions to reduce

microbial resistance and over-prescribing of antibiotics

• Stroke care

North East and North Cumbria• Frail elderly and long term conditions (with

Parkinson’s Disease as a potential early exemplar)

• Citizens with social deprivationConnected Yorkshire• Healthy childhood• Healthy ageing

Confidential between NHSA and N8

The Northern Health Science Alliance: Pipeline

Branding and Launch