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Introduction. Antiplatelet Agents. ADP Receptor Antagonists. CURE Reduction in Cardiovascular Events With Clopidogrel. TRITON-TIMI 38 Risk Reduction Prasugrel vs Clopidogrel. PLATO Major Events: Ticagrelor vs Clopidogrel. Onset of Action. - PowerPoint PPT Presentation

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Page 1: Introduction
Page 2: Introduction
Page 3: Introduction

Introduction

Page 4: Introduction

Antiplatelet Agents

Page 5: Introduction

ADP Receptor Antagonists

Page 6: Introduction

CUREReduction in Cardiovascular Events With

Clopidogrel

Page 7: Introduction

TRITON-TIMI 38Risk Reduction Prasugrel vs Clopidogrel

Page 8: Introduction

PLATOMajor Events: Ticagrelor vs Clopidogrel

Page 9: Introduction

Onset of Action

Page 10: Introduction

Randomized Trials of Antiplatelet Agents

TRITON-TIMI 38 and PLATO

Page 11: Introduction

TRANSLATE-ACS

Page 12: Introduction

After the Patient Goes Home…

Page 13: Introduction

Antiplatelet Use After PCI

Page 14: Introduction

Hospitalized Bleeding

Page 15: Introduction

TRANSLATE-ACSFactors Associated With In-hospital Switch From 1st- to

2nd-generation ADP Receptor Inhibitor

Page 16: Introduction

TRANSLATE-ACSFactors Associated With In-hospital Switch From 2nd to

1st -generation ADP Receptor Inhibitor

Page 17: Introduction

Genetic Effects on Pharmacokinetic and Pharmacodynamic Responses

to Clopidogrel

Page 18: Introduction

TRITON-TIMI 38Risk Reduction: Prasugrel vs Clopidogrel

Page 19: Introduction

TRANSLATE-POPS Design

Page 20: Introduction

POPS – Change in Treatment

Page 21: Introduction

Summary

Page 22: Introduction

Abbreviations

Page 23: Introduction

Abbreviations (cont)

Page 24: Introduction

References

Page 25: Introduction

References (cont)

Page 26: Introduction

References (cont)

Page 27: Introduction

References (cont)