introduction december 3 rd, 2003 presenting: dsbr literature recommendations venusval hammack
TRANSCRIPT
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Introduction
December 3rd, 2003
Presenting:
DSBR
Literature
Recommendations
VenusVal HammackVenusVal Hammack
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Servicemen Workplace
In the heat of battle/ conflict or training maneuvers, the serviceman occasionally does not have the time or supplies to protect themselves in a Chemical agent environment. This is where inadvertent adverse health exposures occur.
During the 90-91 KTO troops where told to ignore the sounding NBC alarms.
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Acta Medica (Hradec Kralove 9 articles from 1999
to 2003 treatment in rats
Address Long term influence of low level sarin
Japanese Research
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Chromato Analysis
J Chromatogr B Biomed Sci Appl
J Chromatogr Sci J Mol Spectrosc J Chromatogr A Rapid detection & ID
of chem agents immunoassay and enzyme inhibition
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Chemical Analysis Chem Biol Interact Anal Chem J Am Chem Soc Analyst J Biol Chem. Catalyzed hydrolysis
of nerve agent by metal compunds and dection of byproducts
Recommended for Committee Review
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Military Medicine
Mil Med (3ea) J R Army Med Corps Mar 2003 study long
term health effects sarin & other anticholinesterase
Dec 2001 psycho-physiological effect of sarin
Demonstrates Spin by DoD to minimalize health effects
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Publications
JAMA Sci Am Lancet BMJ Nature
Better Kill through chemistry
Address quality of life issues
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Occupational
Int J Occup Environ Health
Environ Health Perspect
J Hazard Mater Environ Sci Technol
Close Review by Committee Recommended
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Applied Toxicology
Toxicol Appl Pharmacol
Regul Toxicol Pharmacol
Toxicol Ind Health Toxicol Lett Toxicol Sci Chem Res Toxicol Toxicology
Recommended for Committee Review
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Forensic
J Health Polit Policy Law
Int J Legal Med Leg Med (Tokyo). Forensic Sci Int Harefuah -Hebrew J Assoc Acad Minor
Phys
Recommended for Committee Review
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Genetics
Structure (Camb Nat Struct Biol Nat Med Nat Genet Clin Chim Acta -
Laboratory Medicine
Recommended for Committee Review
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Toxicology
Drug Chem Toxicol Food Chem Toxicol Fundam Appl
Toxicol Hum Exp Toxicol. Bull Environ Contam
Toxicol Arch Toxicol. J Anal Toxicol
Recommended for Committee Review
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Neurotoxicology
J Clin Neurosci Neurochem Res Neurosci Biobehav
Rev Neuroscience Synapse Need much closer
attention
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Pharmacogenetics J Pharmacol Exp
Ther Indian J Physiol
Pharmacol Med Lett Drugs Ther Trends Pharmacol
Sci J Pharm Pharmacol
Address prophilica interactions
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Environmental
Int J Occup Environ Health
Environ Health Perspect
Environ Sci Technol J Hazard Mater J Environ Health Address adverse
exposures
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Biotech
Biotechnol Adv Biochemistry Biomed Environ Sci Biotechnol Adv. Biotechnol Bioeng Bioorg Med Chem Address sarin in
human physiology
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Summary
Veterans demand that this Committee obtain and review the data from
The U.S. Army Center for Health Promotion and Preventive Medicine (USACHPPM) specifically
Cholinesterase Reference Laboratory manages the external quality assurance and quality control program for RBC-ChE activity determinations in support of the nerve agent medical surveillance program.
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Summary
Red-blood cell-cholinesterase monitoring.
Monitoring RBC-ChE by DOD contractors. Contractor may send the blood specimens to the USACHPPM Cholinesterase Reference Laboratory for primary Analysis. See study
Evaluation of Airborne Exposure Limits for G-Agents: Occupational and General Population Exposure Criteria; ERDEC TR-489, Mioduszewski et al., April 1998 and an ERRATA , SAB, Johnson, 2000.
Also other studies citations in handout.