introduction of computational biology€¦ · methods, mathematical modeling and computational...
TRANSCRIPT
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COMPUTATIONAL BIOLOGY SCSB4223
By Rohayanti Hassan (PhD)
Introduction of Computational Biology
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Why Computational Biology?
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Why Computational Biology?
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Do you know, these data belong to?
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Do you know, these data belong to?
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Computational Biology?
• Computational biology involves the development and application of data-analytical and theoretical
methods, mathematical modeling and computational simulation techniques to the study of biological,
behavioral, and social systems.
• The field is broadly defined
and includes foundations
in computer science, applied
mathematics, animation, statist
ics,biochemistry, chemistry, bio
physics, molecular
biology, genetics, genomics, ec
ology, evolution, anatomy, neuroscience, and visualization.
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The Challenges
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Biological Data
Enjoy this video:
Cellular Visions the Inner Life of a Cell
Nuclei, proteins and lipids move with bug-like authority, slithering,
gliding and twisting through 3D space. "All of those things that you see in the animation are going on in every one of your cells in your body
all the time," says XVIVO lead animator John Liebler
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Computational Solution
Computational Solution
1. Pre-Analytics• Discretization• Binning• Normalization• Standard Deviation• Feature Selection• Feature Ranking• etc
2. Post-Analytics• Supervised Learning• Unsupervised Learning• Probabilistic Method• etc
OutputBiological Data
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Current Trend? BIG DATA? DATA SCIENCE
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Prospect as a Data Scientist
8 Data Skills to Get You Hired
Basic Tools Basic Statistics
Machine Learning
Multivariable Calculus
and Linear AlgebraData Munging
Data Visualization &
Communication
Software
Engineering Thinking Like
A Data
Scientist