introduction to chemical research (chem 294)
TRANSCRIPT
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Introduction to Chemical Research (CHEM 294)
Mondays: Lecture1-2pm CRN:
Lab2:15-5:15pm 38609
Mentoring
Proposal
1.Pose a
Research Idea
2. Review Primary
Literature
3. Brainstorm
Project Ideas
4. Pose a Testable
Hypothesis
5. Plan the
Experiments
6. Do Preliminary
Experiments
Proposal to submit for
funding to continue
the project
Introduction to Chemical Research (CHEM 294)
Introduction to
Chemical Research
CHEM 294
Chemical Research
CHEM 488
Mentoring
Chemical Research
CHEM 694
Target audience:
Sophomores
Target audience:
Junior/Senior
Target audience:
Graduate students
Mondays: CRN:
Lecture1-2pm 38609
Lab2:15-5:15pm
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Analy,calInstrumentalLaboratoryCHEM314W
Dr.SarahHayesAsst.Professor
Introduc,ons:1.SyllabusandCourseStructure2.Coursewebsite3.Courseprojects4.OverviewofTechniques5.PaperFormatAc,vity
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Mobilityandtransport
Humanandecosystem
exposureandHealth
I’m Dr. Hayes Research: Geochemistry of toxic metal(loid)s
Bioaccessibility
GeochemistryofMineralweathering
Textbooks:SkoogandHoller6thed
Harris8thed
OnreserveattheRasmussenLibraryfor2hruse
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CourseEvalua,on
ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
ConsumerProductCharacteriza,onProject
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ProjectDefini,onA3-5pgreportdesignedfacilitatelearningaboutyour
productanddevelopaplanforaddressingyourques,ons.
1.IntroducGon-Tellmeaboutyourproduct.2.ProductInformaGon-Researchyourconsumerproduct.3.Ingredients-Learnmoreaboutyourproductingredients.4.ThePlan(Reports1-5)-HowwillyouaddresseachquesGonrelevanttoyourproduct.5.ChooseYourOwnAdventure(Report6)-Proposetwoques,onsofyourchoosing.6.References7.Appendices
StandardAddi,onExperiment1:ElementalAnalysisExperiment2:PlasGcsExperiment3:ColorsExperiment4:SEMExperiment5:CYOAExperiment6:SeparaGonsThroughputofanop,calinstrument
ExperimentsProgression
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1.Procedure
2.Experiment
3.AnnotatedFigures
4.Report
5.PeerReview
6.Revision
ExperimentalProgression
TheSchedule
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Howwillweaddresseachques,on?
ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
WhichtechniqueanswerswhichQ?
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Techniquesforelementalanalysis
Tracemetals
Majorelement
Dissolvemetal
HandheldXRF
HNO3 FlameAA ICP-MS
HCl SEM,XRF ICP-MS
???Other?
Notdetectable?Aluminum
Iron
ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
WhichtechniqueanswerswhichQ?
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Plas,csIden,fica,onProbesvibra,onsoffunc,onalgroupswithinsample• Flametest• FT-IR
Step1:prepara,onofplas,cs
Videoonline
Step2:FT-IRanalysis
Step3:Spectralinterpreta,on
Plas,csIden,fica,on
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h\p://ides3221-2011.blogspot.com/2011/03/plas,cs-iden,fica,on-charts.html
Plas,csIden,fica,onbyothermethods
ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
WhichtechniqueanswerswhichQ?
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Colors-MolecularSpectroscopy
UV-VisFluorescenceFT-IR
Calorimeter-energypermass
h\ps://people.chem.umass.edu/botch/Chem122S08/Chapters/Ch6/CalorimBomb.jpg
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ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
WhichtechniqueanswerswhichQ?
ElectronMicroscopy
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Step1:prepara,onofsamplesStep2:carbonorgoldcoatsamplesStep3:Electronmicroscopy
ElectronMicroscopy
ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
WhichtechniqueanswerswhichQ?
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Youmustproposethreeideasintheprojectproposal
Chooseyourownadventure(CYOA)
Poten,alideas:Iden,fica,on/quan,fica,onormoleculesusingNMRX-raydiffrac,on(XRD)toiden,fymineralspecies(orsomeorganics)
X-rayfluorescence(XRF)toquan,fyelementsAddi,onalSepara,onsAddi,onalcolorexamina,on
ConsumerProduct
ElementalAnalysis
IDPlas,cs
Colors&Calories
ElectronMicroscopy
CYOA
Separa,ons
WhichtechniqueanswerswhichQ?
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HighPerformanceLiquidChromatography(HPLC)Step1:samplesadjustedforconcentra,on
Step2:samplesseparatedincolumnStep3:samplesdetectedusingUV-VisorEDLS
HighPerformanceLiquidChromatography(HPLC)Iden,fiedonthebasisof:
Reten,on,me UV-Visabsorp,onLightsca\ering MassSpectrometry
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GasChromatography-MassSpectrometry(GC-MS)
Step1:sampleinjec,on:liquidorheadspaceStep2:samplesseparatedincolumnStep3:totalsmoleculescountedStep4:moleculesfragmentedStep5:ionfragmentsdetected
GasChromatography-MassSpectrometry(GC-MS)Headspaceordirectliquidinjec,on
Iden,fiedonthebasisof:Reten,on,meMassspectrum