Good Laboratory Practice

The key to the delivery of quality service

Positively United to Support Humanity Guyana’s Faith-Based Holistic HIV Care and Treatment Initiative

Presented by: Lynette Hardy

Learning Objectives

• Review elements of good laboratory practice

• Review our role in laboratory operations• Remind ourselves of our commitment to

provide quality results to our clients• Review our role as a team player in the

deliverance of quality laboratory service

PUSH

The Quality Management System

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Organization Personnel Equipment

Purchasing &

Inventory

Process Control Information

Management

Documents&

Records

Occurrence Management Assessment

Process

Improvement

Customer

Service

Facilities &

Safety

Five basic components

• Resources – organization - Personnel - facilities• The laboratory investigation• Customer service• Results reporting and document control• Quality assurance

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Goal of GLP is to…..

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Obtain results that are: Reliable Repeatable Auditable Acceptable

Aim

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• To strive for 100% level of quality• To be aware that achieving a 99% level of

quality means accepting a 1% error rate

In Guyana a 1% error rate would probably mean everyday.....

• Six hours without electricity• Four hours without running water in the laboratory• Contaminated food being served at hotels• Incorrect blood being transfused• Incorrect results being given to patients• Crash landing of airplanes at Cheddie Jagan International Airport

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Advantages

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• Limits the waste of resources• Ensures high quality of results• Ensures comparability of results• Promotes the mutual recognition of

results

Laboratory errors has severe consequences on..

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time

personnel effort

patient outcomes

Laboratory tests are influenced by…..

Laboratory environment Knowledgeable staff Competent staff Reagents and equipment Quality control Communications Process management Occurrence management Record keeping

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Organization

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Responsibilities, Authorities

CommunicationProvision of

resources

Personnel Human resources Job qualifications Job descriptions Orientation Training Competency assessment Professional development Continuing education

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Equipment

Acquisition Installation Training Calibration Troubleshooting Biomedical services Records

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The laboratory investigation

Sample management Standard Operating Procedure Method validation Quality control Interpretation of results Reporting of results

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Customer Service

Customer identification Customer needs Customer feedback

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Documents Recordscreation collection

revisions and review review

control and distribution storage

retention

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Quality Assurance

Occurrence Management Complaints Documentation Root cause analysis Corrective actions Preventive actions

PUSH

ImplementingQuality Management

does notguarantee

anERROR-FREE

Laboratory

But it detects errors that may occur and prevents them from recurring

A laboratory is a complex system and all aspects

must function properly to achieve quality

Thank YouThank You