is it possible to measure up to freelite · belgium, netherlands, luxembourg: the binding site...
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The Specialist Protein Company
Is it possible to measure up to Freelite? N-Latex FLC Freelite NO FDA Regulatory Compliant YES
NO IMWG Guidelines for Diagnosis1 YES
NO IMWG Guidelines for Monitoring2 YES
NO IMWG Guidelines for Prognosis2 YES
NO Identifi cation of AKI MM3 YES
NO More than 10 years of clinical data YES
<25 Provenance - publications >2,000
<7.5%4 Consistency (batch to batch variation) <6%5
YES Antigen Excess Protection YES
≤5% Antigen Excess Incidence6 ≤ 1%
≥0.940 Linearity7 ≥0.988
Limited Dedicated Global Technical Support YES
2 Range of Platforms >15
No Dedicated EQA Scheme YES
<100% Sensitivity (LCMM)8 100%
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Freelite outweighs the competition ✓
Free Light Chain Assays for Multiple Myeloma
The GOLD STANDARD from Binding Site
Free Light Chain Assays for Multiple Myeloma
References:
1 Rajkumar SV, et al. Lancet Oncol 2014; 15: E538-482 Dispenzieri A, et al. Leukemia 2009; 23: 251-2243 Hutchison CA, et al. Nature Rev Nephrol 2012:8 (1) 43-514 Siemens data “Add Consistency to Your Results” 05-20125 Binding Site data APDOC046 Burden JM, et al. presented at AACC 20127 Sharrod-Cole H, et al. Biochimica Clinica 2013; 37:T390a8 Drayson M, et al. Clin Lymphoma Myeloma 2009; 9: A346a
Freelite, SPAPLUS & Optilite are registered trademarks of The Binding Site Group Ltd (Birmingham, UK) in certain countries.
BNTMII is a trademark of Siemens Healthcare Diagnostics Inc.
Go to www.bindingsite.com to contact us in over 80 countries. www.bindingsite.com
Head Office:The Binding Site Group LtdUnited KingdomTel: +44 (0)121 456 [email protected]
USA, Canada, Latin America:The Binding Site Inc.USAToll Free: 800 633 [email protected]
Germany, Austria, Switzerland:The Binding Site GmbHGermanyTel: +49 (0)6202 9262 0 [email protected]
France:The Binding Site FranceFrance Tel: +33 (0)[email protected]
Spain:The Binding Site SpainSpainTel: +34 934676539 [email protected]
Czech Republic, Slovak Republic:The Binding Site s.r.o.Czech RepublicTel: +420 223 013 988-9 [email protected]
January 2015
MKG786.EBelgium, Netherlands, Luxembourg:The Binding Site SPRL/BVBABelgiumTel: +32 (0)3 242 88 [email protected]
Italy:The Binding Site ItalyItalyTel. +39 035 [email protected]
Freelite® N-Latex
System Optilite® SPAPLUS® BNTMII
κ λ κ λ κ λ
Measuring range mg/L 2.9-127 5.2-139 4.0-180 4.5-165 3.5-110 1.9-60
Sensitivity mg/L 0.58 1.3 0.4 0.45 0.175 0.475
Within run precision <5.2% <3.4% <3.3% <3.7% <5% <5%
Between run precision <2.9% <4.2% <4.2% <5.7% <6.5% <6.5%
Calibrator dilution Onboard Calibrator set Onboard
On board stability days 30 40 25
Automatic antigen excess check Yes Yes Yes
Time to first result 17mins 14mins 15mins
Throughput for 60 samples* 1hr 35mins 2hrs 33mins 3hrs 20mins
*Time taken from first result to last for 40 Multiple Myeloma and 20 normal samples run against both kappa and lambda.
The facts? See the difference a Binding Site system makes!