issn 1341-7568 genes genetic systems ggenetic
TRANSCRIPT
GGS
Genes &GeneticSystems
Genes & Genetic Systems
C O N T E N T S
(The Genetics Society of Japan)
April 2021 Vol.96, No.2
Apri l 2021 Vol .96, No.2
ISSN 1341-7568
https: / /gsj3.org
Front inset: Plants are often characterized by petal color variation within species, a phenomenon known as flower color polymorphism. Although biotic and abiotic elements are important determinants of flower color polymorphism, selectively neutral factors have also been implicated in its maintenance. Geranium thunbergii (Geraniaceae) is a perennial herb distributed throughout the Japanese archipelago. As shown in the inset on the cover, the species displays a geographic cline in floral color: individuals having purple petals are distributed in the western part, while those having white or pale pink petals are distributed in the eastern part. Both flower colors co-occur in central Honshu, where the cover photo was taken. In this issue, Seikan Kurata and colleagues developed and characterized 19 microsatellite markers to explore the formation and maintenance mechanisms of flower color polymorphism. A preliminary population analysis showed that three populations in western, central and eastern parts of the country had different genetic structure.
Full papersBioinformatic analysis of differentially
expressed genes as prognostic markers in pheochromocytoma and paraganglioma tumors
Zhen Shi, Xiaodi Kong, Cheng Li, Hui Liu, Abdulhafiz Imam Aliagan, Li Liu, Yue Shi, Xiao Shi, Binbin Ma, Ruiqi Jin, Shizhuo Wang, Ding Pan and Juyu Tang
55
SELL and IFI44 as potential biomarkers of Sjögren’s syndrome and their correlation with immune cell infiltration
Hua Xu, Jia Chen, Yang Wang, Yanmei Wu and Yingjie Liang
71
Genome-wide analyses of tandem repeats and transposable elements in patchouli
Linqiu Liu, Junjun Li, Jiawei Wen and Yang He
81
A 1-bp deletion in Mc1r in a Norway rat (Rattus norvegicus) from Sado Island, Japan gives rise to a yellowish color variant: an insight into mammalian MC1R variants
Takeru Tsunoi, Koki Noju, Takeshi Eto and Hitoshi Suzuki
89
Short communicationDevelopment and characterization of nuclear
microsatellite markers to reveal the neutral demographic background of flower color polymorphism in Geranium thunbergii (Geraniaceae)
Seikan Kurata, Shota Sakaguchi, Hitomi Mishima, Takashi Tsuchimatsu and Motomi Ito
99
Corrigendum 105
Front inset: Plants are often characterized by petal color variation within species, a phenomenon known as flower color polymorphism. Although biotic and abiotic elements are important determinants of flower color polymorphism, selectively neutral factors have also been implicated in its maintenance. Geranium thunbergii (Geraniaceae) is a perennial herb distributed throughout the Japanese archipelago. As shown in the inset on the cover, the species displays a geographic cline in floral color: individuals having purple petals are distributed in the western part, while those having white or pale pink petals are distributed in the eastern part. Both flower colors co-occur in central Honshu, where the cover photo was taken. In this issue, Seikan Kurata and colleagues developed and characterized 19 microsatellite markers to explore the formation and maintenance mechanisms of flower color polymorphism. A preliminary population analysis showed that three populations in western, central and eastern parts of the country had different genetic structure.
Full papersBioinformatic analysis of differentially
expressed genes as prognostic markers in pheochromocytoma and paraganglioma tumors
Zhen Shi, Xiaodi Kong, Cheng Li, Hui Liu, Abdulhafiz Imam Aliagan, Li Liu, Yue Shi, Xiao Shi, Binbin Ma, Ruiqi Jin, Shizhuo Wang, Ding Pan and Juyu Tang
55
SELL and IFI44 as potential biomarkers of Sjögren’s syndrome and their correlation with immune cell infiltration
Hua Xu, Jia Chen, Yang Wang, Yanmei Wu and Yingjie Liang
71
Genome-wide analyses of tandem repeats and transposable elements in patchouli
Linqiu Liu, Junjun Li, Jiawei Wen and Yang He
81
A 1-bp deletion in Mc1r in a Norway rat (Rattus norvegicus) from Sado Island, Japan gives rise to a yellowish color variant: an insight into mammalian MC1R variants
Takeru Tsunoi, Koki Noju, Takeshi Eto and Hitoshi Suzuki
89
Short communicationDevelopment and characterization of nuclear
microsatellite markers to reveal the neutral demographic background of flower color polymorphism in Geranium thunbergii (Geraniaceae)
Seikan Kurata, Shota Sakaguchi, Hitomi Mishima, Takashi Tsuchimatsu and Motomi Ito
99
Corrigendum 105
Genes & Genetic Systems(The Official Journal of the Genetics Society of Japan)
President IWASAKI, Hiroshi (DNA Repair, Homologous Recombination)Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, S2-7, 4259 Nagatsuta, Midori, Yokohama, Kanagawa 226-8503, JapanTel. +81-45-924-5168 ; fax +81-45-924-5207 ; [email protected]
Editor-in-Chief ARAKI, Hiroyuki (DNA Replication, Yeast Genetics)National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan/Joint-Support-Center for Data Science Research, ROIS, TokyoTel. +81-55-981-6754 ; fax +81-55-981-6762 ; [email protected]
Vice Editor-in-Chief MASUYA, Hiroshi (Bioinformatics, Mouse Genetic)RIKEN BioResource Research Center, 3-1-1, Kouyadai, Tsukuba, Ibaraki 305-0074, JapanTel. +81-29-829-9112 ; fax +81-29-836-9337 ; [email protected]
Managing Editor NISHIHARA, Hidenori (Transposable Elements, Molecular Evolution, Phylogenetics, Mammalian Evolution)Department of Life Science and Technology, Tokyo Institute of Technology, 4259-S2-17, Nagatsuta-cho, Midori-ku, Yokohama 226-8501, JapanTel. +81-45-924-5742 ; [email protected]
Reviews Editor ISHII, Kojiro (Yeast Genetics, Chromosome Biology)School of Environmental Science and Engineering, Kochi University of Technology, 185 Miyanokuchi, Tosayamada-cho, Kami, Kochi 782-8502, JapanTel. +81-887-57-2511 ; fax +81-887-57-2520 ; [email protected]
GGS Prize Editor KOGA, Akihiko (Primates, Evolution)Primate Research Institute, Kyoto University, Inuyama, Aichi 484-8506, JapanTel. +81-568-63-0526 ; fax +81-568-63-0085 ; [email protected]
Editors AKASHI, Hiroshi (Population Genetics, Molecular Evolution, Evolutionary Genetics)Laboratory of Evolutionary Genetics, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, JapanTel. +81-055-981-6793 ; [email protected]
ASAI, Kei (Bacterial Genetics, Regulation of Gene Expression)Department of Bioscience, Faculty of Life Sciences. Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, JapanTel. +81-03-5477-2758 ; fax +81-3-5477-2668 ; [email protected]
CARR, Antony M. (Checkpoints, DNA Damage Response)Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, BN1 9RR, UKTel. +44-1273-678122 ; fax +44-1273-678121 ; [email protected]
FAWCETT, Jeffrey (Genome Evolution)RIKEN iTHEMS, 2-1 Hirosawa, Wako, Saitama 351-0198, JapanTel. +81-48-462-1111 (ext. 3086) ; fax +81-48-462-1359 ; [email protected]
FUKUI, Kiichi (Chromosome Science, Imaging)Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, JapanTel. +81-6-6879-7440 ; fax +81-6-6879-7440 ; [email protected]
GALANDE, Sanjeev (Chromatin Biology)Centre of Excellence in Epigenetics, Indian Institute of Science Education and Research (IISER), Sixth floor, First Tower, Sai Trinity Building, Garware Circle, Sutarwadi, Pashan, Pune, Maharashtra 411021, IndiaTel. +91-20-2590-8001 ; fax +91-20-2586-5315 ; [email protected]
HABER, James E. (Yeast Genetics, Homologous Recombination, DNA Repair)MS029, Rosensteil Center, Brandeis University, 415 South St, Waltham, MA 02454-911, USATel. +1-781-736-2462 ; fax +1-781-736-2405 ; [email protected]
HIRANO, Hiro-Yuki (Developmental Genetics, Plant)Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-8654, JapanTel. +81-3-5841-4056 ; fax +81-5841-4056 ; [email protected]
ICHIYANAGI, Kenji (Genetics, Epigenetics, Genomics, Epigenomics, Molecular Biology, Bioinformatics)Graduate School of Bioagricultural Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, JapanTel. +81-52-789-4066 ; fax +81-52-789-5748 ; [email protected]
IMOTO, Issei (Human Genetics)Division of Molecular Genetics, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, JapanTel. +81-52-764-9888 ; fax +81-52-764-9888 ; [email protected]
INNAN, Hideki (Population Genetics, Genome evolution)Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Kanagawa 240-0193, JapanTel. +81-46-858-1600 ; fax +81-46-858-1544 ; [email protected]
INOUE, Ituro (Human Genetics)National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, JapanTel. +81-55-981-6795 ; fax +81-55-981-6715 ; [email protected]
ISHINO, Yoshizumi (Archaea Molecular Biology and Genetics)Department of Bioscience & Biotechnology, Graduate School of Bioresource & Bioenvironmental Sciences, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka 812-8581, JapanTel. +81-92-642-4217 ; fax +81-92-642-3085 ; [email protected]
ITOH, Masanobu (Drosophila Genetics, Bombyx Genetics, Transposable Elements)Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, JapanTel. +81-75-724-7788 ; fax +81-75-724-7708 ; [email protected]
KAKUTANI, Tetsuji (Epigenetics, Epigenomics)Department of Biological Sciences, Graduate School of Science, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, JapanTel. +81-3-5841-4454 ; fax +81-3-5841-4466 ; [email protected]
KIM, Hie Lim (Population Genetics, Genomics)Asian School of the Environment, SCELSE, Nanyang Technological University, 50 Nanyang Ave, N2-01C-52, 639798, SingaporeTel. +65-6794-3846 ; [email protected]
KIMURA, Ryosuke (Evolutionary Genetics, Molecular Anthropology, Human Genetics)Department of Human Biology and Anatomy, Graduate School of Medicine, University of the Ryukyus, Uehara 207, Nishihara-cho, Okinawa 903-0215, JapanTel. +81-98-895-1211 ; fax +81-98-895-1400 ; [email protected]
KINOSHITA, Tetsu (Plant Genetics, Epigenetics)Kihara Institute for Biological Research, Yokohama City University, 641-12 Maioka, Totsuka, Yokohama, Kanagawa 244-0813, JapanTel. +81-45-820-2468 ; [email protected]
KOBAYASHI, Takehiko (Yeast Genetics, Genome Stability and Amplification)Institute for Quantitative Biosciences (IQB), The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113- 0032, JapanTel. +81-3-5841-7861 ; fax +81-3-5841-8472 ; [email protected]
KODZIUS, Rimantas (Molecular Biology, Omics)Department of Mathematics & Natural Sciences, The American University of Iraq, Sulaimani Raparin, Kirkuk Main Road, Sulaimani, IraqTel. +96-477-3836-3674 ; [email protected] or [email protected]
KUROIWA, Asato (Animal Cytogenetics)Department of Biological Sciences, School of Science, Hokkaido University, Kita-10 Nishi-8, Kita-ku, Sapporo 060-0810, JapanTel. +81-11-706-2752 ; fax +81-11-706-2752 ; [email protected]
KUSUMI, Junko (Population Genetics, Molecular Evolution, Evolutionary Genetics)Department of Environmental Changes, Faculty of Social and Cultural Studies, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, JapanTel. +81-92-802-5649 ; fax +81-92-802-5649 ; [email protected]
LAI, Poh San (Human Genetics)Division of Human Genetics, Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, National University Hospital, NUHS Tower Block Level 12, 1E Kent Ridge, Singapore 119228Tel. +65-6772-4112 ; fax +65-6779-7486 ; [email protected]
LEE, Fang-Jen (Scott) (Protein and Membrane Trafficking)Institute of Molecular Medicine, College of Medicine, National Taiwan University, 7 Chung Shan South Road, Taipei 100, TaiwanTel. +886-2-23123456 ext. 65730 ; fax +886-2-23957801 ; [email protected]
MAKI, Hisaji (Mutagenesis, Carcinogenesis, DNA replication, DNA repair)Division of Biological Science, Graduate School of Science and Technology, Nara Institute of Science and Technology, Takayama-cho 8916-5, Ikoma, Nara 630-0101, JapanTel. +81-743-72-5490 ; fax +81-743-72-5499 ; [email protected]
MASOUDI-NEJAD, Ali (Bioinformatics, Systems Biology)Laboratory of Bioinformatics and Bioknowledge Systems, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, IranTel. +98-912-585-1148 ; fax +98-21-6640-4680 ; [email protected]
MORI, Ikue (Neurogenetics, Caenorhabditis elegans)Neuroscience Institute and Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, JapanTel. +81-52-789-4560 ; fax +81-52-789-4559 ; [email protected]
MURAI, Koji (Molecular and General Genetics in Higher Plant)Department of Bioscience and Biotechnology, Fukui Prefectural University, 4-1-1 Matsuoka-Kenjojima, Eiheiji-cho, Yoshida-gun, Fukui 910-1195, JapanTel. +81-776-61-6000 ; fax +81-776-61-6015 ; [email protected]
NAKABEPPU, Yusaku (DNA Repair, Mutagenesis, Carcinogenesis, Neuroscience)Division of Neurofucntional Genomics, Department of Immunobiology and Neuroscience, Medical Institute of Medical Biology, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, JapanTel. +81-92-642-6800 ; fax +81-92-642-6791 ; [email protected]
NASUDA, Shuhei (Plant Cytogenetics, Plant Genetic Resources)Graduate School of Agriculture, Kyoto University, Kitashirakawaoiwake-cho, Sakyo-ku, Kyoto 606-8502, JapanTel. +81-75-753-6061 ; fax +81-75-753-6047 ; [email protected]
NIKAIDO, Masato (Evolutionary Biology, Molecular Biology, Bioinformatics)School and Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, W3-43, 2-12-1 Ookayama, Meguro, Tokyo 152-8550, JapanTel. +81-3-5734-2659 ; fax +81-3-5734-2946 ; [email protected]
NIKI, Hironori (Bacterial and Yeast Genetics, Chromosome Dynamics)National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, JapanTel. +81-55-981-6870 ; fax +81-55-981-6826 ; [email protected]
NISHIDA, Yasuyoshi (Developmental Genetics, Drosophila)[email protected]
NONOMURA, Ken-Ichi (Plant Genetics, Reproduction)Plant Cytogenetics Laboratory, National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411-8540, JapanTel. +81-55-981-6872 ; fax +81-55-981-5872 ; [email protected]
OKADA, Yukinori (Human Genetics, Bioinformatics, Statistical Genetics)Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanTel. +81-6-6879-3971 ; [email protected]
REHA-KRANTZ, Linda J (DNA Replication, Genetics of Phage and Yeast)University of Alberta (Emeritus)[email protected]
ROTHSTEIN, Rodney (DNA Recombination, Genome Rearrangements)Department of Genetics and Development, Columbia University, 701W. 168th St., New York, NY10032, USATel. +1-212-305-1733 ; fax 1-212-923-2090 ; [email protected]
SATTA, Yoko (Molecular Evolutionary Genetics, Primate)Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Kanagawa 240-0193, JapanTel. +81-468-58-1574 ; fax +81-468-58-1544 ; [email protected]
SAWAMURA, Kyoichi (Evolutionary Genetics, Drosophila)Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, JapanTel. +81-29-853-4669 ; fax +81-29-853-6614 ; [email protected]
SEO, Yeon-Soo (DNA Replication, Cell Cycle)Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373-1 KusungDong, Yusung-ku, Daejeon 305-701, KoreaTel. +82-42-869-2637 ; fax +82-42-869-2610 ; [email protected]
SHIROISHI, Toshihiko (Mammalian Genetics)RIKEN BioResource Research Center, 3-1-1 Koyadai Tsukuba, Ibaraki 305-0074, JapanTel. +81-29-836-9044 ; fax +81-29-836-9144 ; [email protected]
SHIWA, Yuh (Genomics, Bioinformatics)Department of Molecular Microbiology, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya, Tokyo 156-8502, JapanTel. +81-3-5477-3185 ; fax +81-3-5477-2537 ; [email protected]
SIMKOVA, Hana (Plant Genomics)Centre of Plant Structural and Functional Genomics, Institute of Experimental Botany, CZ-78371 Olomouc, Czech RepublicTel. +420-585-238-715 ; fax +420-585-238-704 ; [email protected]
TAJIMA, Atsushi (Human Genetics)Department of Bioinformatics and Genomics, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, JapanTel. +81-76-265-2715 ; fax +81-76-234-4249 ; [email protected]
TAKAHASHI, Aya (Drosophila Genetics, Population and Evolutionary Genetics)Department of Biological Sciences, Tokyo Metropolitan University, 1-1 Minamiosawa, Hachioji, Tokyo 192- 0397, JapanTel. +81-42-677-1111 ext. 3733 ; [email protected]
TAKAHASHI, K. Ryo (Quantitative Genetics, Population Biology)Faculty of Life Sciences, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555, JapanTel. +81-75-705-3114 ; [email protected]
TANAKA, Shuuitsu (DNA Repair, Apoptosis, Fungi Genetics)Department of Regulatory Biology, Faculty of Science, Saitama University, 255 Shimoohkubo, Sakura-ku, Saitama 338-8570, JapanTel. +81-48-858-3414 ; fax +81-48-858-3414 ; [email protected]
TERACHI, Toru (Organellar Genetics)Faculty of Life Sciences, Kyoto Sangyo University, Motoyama, Kamigamo, Kita-ku, Kyoto 603-8555, JapanTel. +81-75-705-1896 ; fax +81-75-705-1914 ; [email protected]
THON, Genevieve (Yeast Genetics, Heterochromatin and Chromosome Dynamics)Department of Biology, University of Copenhagen, BioCenter, Ole Maaloes vej 5, 2200 Copenhagen, DenmarkTel. +45-3532-2113 ; fax +45-3532-2128 ; [email protected]
TING, Chau-Ti (Drosophila Genetics, Population Genetics and Molecular Evolution)Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, TaiwanTel. +886-2-3366-2522 ; fax +886-2-2367-3374 ; [email protected]
TSUMURA, Yoshihiko (Ecological Genetics, Forest Genetics)Faculty of Life & Environmental Sciences, University of Tsukuba 1-1-1 Tennodai, Tsukuba, Ibaraki 305- 8572, JapanTel. & fax +81-29-853-4629 ; [email protected]
WANG, Hurng-Yi (Virology, Molecular Evolutionary Genetics)Graduate Institute of Clinical Medicine, National Taiwan University, Taipei 100, TaiwanTel. +886-2-23123456 ext. 66614 ; fax +886-2370-9820 ; [email protected]
WANG, Ting-Fang (Chromosome Biology)Institute of Molecular Biology, Academia Sinica, Nankang, Taipei 11529, TaiwanTel. +886-2-2789-9188 ; fax +886-2-2782-6085 ; [email protected]
XU, Guoliang (Mammalian Epigenetics)Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, ChinaTel. +86-21-5492-1332 ; fax +86-21-5492-1266 ; [email protected]
XU, Shuhua (Population Genomics, Human Genetics)Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology, Shanghai 200031, ChinaTel. +86-21-54920479 ; fax +86-21-54920451 ; [email protected]
Instructions to Authors can be found at https://gsj3.org/ggs/instructions_for.html
ENDO, Takashi, Ryukoku Univ.DOLEZEL, Jaroslav, Inst. Exper. Bot., Czech RepublicFUJIKAWA, Kazuo, Kindai Univ.GAO, Xiang, Nanjing Univ., ChinaGOJOBORI, Takashi, KAUST, Saudi ArabiaGONDO, Yoichi, Tokai Univ.IKEUCHI, Tatsuro, Tokyo Medical and Dental Univ.ISHIWA, Sadao, Ochanomizu Univ.ITOH, Tateo, Shinshu Univ.KAWAGISHI, Ikuro, Hosei Univ.KAWANO, Shigeyuki, Univ. TokyoLI, Wen-Hsiung, Academia Sinica, TaiwanMATSUDA, Yoichi, Nagoya Univ.MATSUURA, EtsukoMIYATA, Takashi, Biohistory Res. Hall.MORIKAWA, Hiromichi, Hiroshima Univ.MUKAI, Yasuhiko, Osaka Kyoiku Univ.MURATA, Minoru, Okayama Univ. (Emeritus)
NAKATSUJI, Norio, Kyoto Univ. OGAWA, Hideyuki, Iwate Nurse College OHSHIMA, Yasumi, Kyushu Univ.SEONG, Je Kyung, Seoul Nat. Univ., KoreaSHI, Suhua, Sun Yat-sen Univ., ChinaSHINAGAWA, Hideo, Osaka Univ.SUGIURA, Masahiro, Nagoya Univ.TACHIDA, Hidenori, Kyushu Univ.TAJIMA, Fumio, Univ. TokyoTAKAGI, Nobuo, Hokkaido Univ.TANG, Kun, CAS-MPG Partner Inst. for Comput. Biol., ChinaTATENO, Yoshio, Natl. Inst. Genet. TOH-E, Akio, Chiba Univ.TSUJIMOTO, Hisashi, Tottori Univ.TSUNEWAKI, Koichiro, Kyoto Univ. (Emeritus)YONEKAWA, Hiromichi, Tokyo Metro. Inst. Med. Sci.
Advisory Board
YAMAMOTO, Masa-Toshi (Drosophila Genetics)Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, JapanTel. +81-55-981-6824 ; fax +81-55-981-6828 ; [email protected]
YAMANISHI, Yoshihiro (Bioinformatics, Computational Drug Discovery)Department of Bioscience and Bioinformatics, Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology, 680-4 Kawazu, Iizuka, Fukuoka 820-8502, JapanTel. +81-948-29-7821 ; fax +81-948-29-7801 ; [email protected]
YAO, Meng-Chao (Genome Dynamics)Institute of Molecular Biology, Academia Sinica, Nankang, Taipei 11529, TaiwanTel. +886-2-2789-3117 ; fax +886-2-2789-9988 ; [email protected]
YEN, Hsueh-Chi (Sherry) (Protein Degradation)Institute of Molecular Biology, Academia Sinica, Nankang, Taipei 11529, TaiwanTel. +886-2-2789-9212 ; fax +886-2-2782-6085 ; [email protected]
The Genetics Society of Japan
Office 1111 Yata, Mishima, Shizuoka 411-8540, Japan. Tel. & fax + 81-55-981-6736. E-mail: [email protected] for 2021–2022 President IWASAKI, Hiroshi, Tokyo Institute of Technology Home Secretary NONOMURA, Ken-Ichi, National Institute of Genetics Home Secretary HIRATA, Tatsumi, National Institute of Genetics Foreign Secretary HISHIDA, Takashi, Gakushuin University Secretary for Planning and Meeting OKI, Masaya, University of Fukui Secretary for Planning and Meeting NAKABEPPU, Yusaku, Kyushu University Secretary for Planning and Meeting FARCETT, Jeffrey, Riken Institute Treasurer KITANO, Jun, National Institute of Genetics Editor-in-Chief ARAKI, Hiroyuki, National Institute of Genetics Vice Editor-in-Chief MASUYA, Hiroshi, Riken Institute Secretary at large ARAKI, Kimi, Kumamoto University Secretary at large ENDO, Toshinori, Hokkaido University Secretary at large ICHIYANAGI, Kenji, Nagoya University Secretary at large IKEMURA, Toshimichi, Nagahama Institute of Science and Technology Secretary at large MAKI, Hisaji, Nara Institute of Science and Technology Secretary at large MIYAGISIMA, Shin-ya, National Institute of Genetics Secretary at large MURAI, Koji, Fukui Prefectural University Secretary at large MURAYAMA, Yasuto, National Institute of Genetics Secretary at large NIKAIDO, Masato, Tokyo Institute of Technology Secretary at large OHNO, Mizuki, Kyushu University Secretary at large SASAKI, Mariko, The University of Tokyo Secretary at large SAZE, Hidetoshi, Okinawa Institute of Science and Technology (OIST) Secretary at large SUGIMOTO, Michihiko, Riken Institute
Council BoardCHIGI, Yuta, Tokushima UniversityDAIGAKU, Yasukazu, Tohoku UniversityGONDO, Yoichi, Tokai UniversityISHIGURO, Kei-ichi, Kumamoto UniversityKANAZAWA, Akira, Hokkaido UniversityKINOSHITA, Tetsu, Yokohama City UniversityKOBAYASHI, Takehiko, The University of TokyoKOGA, Akihiko, Kyoto UniversityKONDO, Rumi, Ochanomizu UniversityKUBO, Tomohiko, Hokkaido UniversityKUROIWA, Asato, Hokkaido UniversityNIKI, Hironori, National Institute of GeneticsNITASAKA, Eiji, Kyushu University
SADO, Takashi, Kindai UniversitySATO, Yutaka, National Institute of GeneticsSATTA, Yoko, SOKENDAISAWAMURA, Kyoichi, University of TsukubaSEKI, Yoshiyuki, Kwansei Gakuin UniversitySHINOHARA, Miki, Kindai UniversitySUGASAWA, Kaoru, Kobe UniversityTAKAHASHI, Aya, Tokyo Metropolitan UniversityTAKANO, Toshiyuki, Kyoto Institute of TechnologyTAMURA, Koichiro, Tokyo Metropolitan UniversityTANAKA, Wakana, Hiroshima UniversityTESHIMA, Kosuke, Kyushu UniversityYOSHIYAMA, Kaoru, Tohoku University
The Genetics Society of Japan was established in 1920 with the aim of promoting research in genetics and related fields, and of providing its members with opportunities for interac-tion. The Society accomplishes this aim mainly by publishing a bimonthly English journal, Genes & Genetic Systems, and by holding an annual meeting that gives the members the oppor-tunity of reporting their work for discussion. At the general assembly of this meeting, the general policies and financial issues involved in the running of the Society are discussed and decided. The Society has two administrative organs that interact: one is the Society office, which is composed of the president, home secretary, foreign secretary, secretary for planning and meetings, treasurer, editor-in-chief, vice editor-in-chief, and several secretaries at large, and the other is the council board, which consists of members elected from the national constituency and from regional constituencies. Both groups
are responsible for laying down general policies and financial issues for the Society. The Society appoints some members and non-member experts as editors to help the editor-in-chief; they are in charge of receiving and handling manuscripts. The Society also has an advisory board, which gives the Society office aca-demic advice and assistance with publishing the journal.
Publication of the journal is partly supported by a Grant-in-Aid for Publication of Scientific Research Result from the Japan Society for the Promotion of Science (JP20HP2004).
The office of the Genetics Society of Japan is in the National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411-8540, Japan. Tel. & fax, + 81-55-981-6736. E-mail: [email protected]
GGS
Genes &GeneticSystems
Genes & Genetic Systems
C O N T E N T S
(The Genetics Society of Japan)
April 2021 Vol.96, No.2
Apri l 2021 Vol .96, No.2
ISSN 1341-7568
https: / /gsj3.org
Front inset: Plants are often characterized by petal color variation within species, a phenomenon known as flower color polymorphism. Although biotic and abiotic elements are important determinants of flower color polymorphism, selectively neutral factors have also been implicated in its maintenance. Geranium thunbergii (Geraniaceae) is a perennial herb distributed throughout the Japanese archipelago. As shown in the inset on the cover, the species displays a geographic cline in floral color: individuals having purple petals are distributed in the western part, while those having white or pale pink petals are distributed in the eastern part. Both flower colors co-occur in central Honshu, where the cover photo was taken. In this issue, Seikan Kurata and colleagues developed and characterized 19 microsatellite markers to explore the formation and maintenance mechanisms of flower color polymorphism. A preliminary population analysis showed that three populations in western, central and eastern parts of the country had different genetic structure.
Full papersBioinformatic analysis of differentially
expressed genes as prognostic markers in pheochromocytoma and paraganglioma tumors
Zhen Shi, Xiaodi Kong, Cheng Li, Hui Liu, Abdulhafiz Imam Aliagan, Li Liu, Yue Shi, Xiao Shi, Binbin Ma, Ruiqi Jin, Shizhuo Wang, Ding Pan and Juyu Tang
55
SELL and IFI44 as potential biomarkers of Sjögren’s syndrome and their correlation with immune cell infiltration
Hua Xu, Jia Chen, Yang Wang, Yanmei Wu and Yingjie Liang
71
Genome-wide analyses of tandem repeats and transposable elements in patchouli
Linqiu Liu, Junjun Li, Jiawei Wen and Yang He
81
A 1-bp deletion in Mc1r in a Norway rat (Rattus norvegicus) from Sado Island, Japan gives rise to a yellowish color variant: an insight into mammalian MC1R variants
Takeru Tsunoi, Koki Noju, Takeshi Eto and Hitoshi Suzuki
89
Short communicationDevelopment and characterization of nuclear
microsatellite markers to reveal the neutral demographic background of flower color polymorphism in Geranium thunbergii (Geraniaceae)
Seikan Kurata, Shota Sakaguchi, Hitomi Mishima, Takashi Tsuchimatsu and Motomi Ito
99
Corrigendum 105
Front inset: Plants are often characterized by petal color variation within species, a phenomenon known as flower color polymorphism. Although biotic and abiotic elements are important determinants of flower color polymorphism, selectively neutral factors have also been implicated in its maintenance. Geranium thunbergii (Geraniaceae) is a perennial herb distributed throughout the Japanese archipelago. As shown in the inset on the cover, the species displays a geographic cline in floral color: individuals having purple petals are distributed in the western part, while those having white or pale pink petals are distributed in the eastern part. Both flower colors co-occur in central Honshu, where the cover photo was taken. In this issue, Seikan Kurata and colleagues developed and characterized 19 microsatellite markers to explore the formation and maintenance mechanisms of flower color polymorphism. A preliminary population analysis showed that three populations in western, central and eastern parts of the country had different genetic structure.
Full papersBioinformatic analysis of differentially
expressed genes as prognostic markers in pheochromocytoma and paraganglioma tumors
Zhen Shi, Xiaodi Kong, Cheng Li, Hui Liu, Abdulhafiz Imam Aliagan, Li Liu, Yue Shi, Xiao Shi, Binbin Ma, Ruiqi Jin, Shizhuo Wang, Ding Pan and Juyu Tang
55
SELL and IFI44 as potential biomarkers of Sjögren’s syndrome and their correlation with immune cell infiltration
Hua Xu, Jia Chen, Yang Wang, Yanmei Wu and Yingjie Liang
71
Genome-wide analyses of tandem repeats and transposable elements in patchouli
Linqiu Liu, Junjun Li, Jiawei Wen and Yang He
81
A 1-bp deletion in Mc1r in a Norway rat (Rattus norvegicus) from Sado Island, Japan gives rise to a yellowish color variant: an insight into mammalian MC1R variants
Takeru Tsunoi, Koki Noju, Takeshi Eto and Hitoshi Suzuki
89
Short communicationDevelopment and characterization of nuclear
microsatellite markers to reveal the neutral demographic background of flower color polymorphism in Geranium thunbergii (Geraniaceae)
Seikan Kurata, Shota Sakaguchi, Hitomi Mishima, Takashi Tsuchimatsu and Motomi Ito
99
Corrigendum 105