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ISSN 0036-8075 12 MAY 1995 VOLUME 268 NUMBER 5212 AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE NEWS & COMMENT Dispute Splits Schizophrenia Study A Glimpse of an Elusive Quarry O'Leary Takes Swipe at Bureaucracy U.K. Tries to Set Priorities With the Benefit of Foresight Russian Arctic Battles Pipeline Leak Japan: Chiba's Heavy-Ion Accelerator Battles Cancer and Critics 792 793 794 795 796 797 RESEARCH NEWS noMA AueA New Clue to Prostate Cancer Spread 799 Battle Is Joined Over Gamma Bursts 800 Study Unveils Climate Cooling Caused 802 by Pollutant Haze Researchers Get a Sharper Image r 803 of the Human Brain Keeping the Kilo From Gaining Weight 804 Umbilical Cords: Turning Garbage Into Clinical Gold New Compounds Make Light of Pests 805 806 POLICY FORUM The World's Forests: Need for a Policy Appraisal N. Myers 823 PERSPECTIVES -- Neuropeptides, Adenylyl Cyclase, and r 825 Memory Storage E. Kandel and T. Abel r 827 A Fixation with Fixation G. J. Leigh ARTICLE From Microwave Anisotropies to Cosmology D. Scott, J. Silk, M. White 829 DEPARTMENTS THIS WEEK IN SCIENCE EDITORIAL Degrees of Uncertainty 781 783 LETTERS 785 Impetus for NSF Policy: D. N. Langenberg * Who Survived the Cretaceous?: D. H. Janzen * Author- ship Criteria: J. P. Kassirer * EPA and Biotechnol- ogy Regulation: L. R. Goldman * Reading Disabil- ity, Attention-Deficit Hyperactivity Disorder, and the Immune System: R. P. Warren, J. D. Odell, W. L. Warren, R. A. Burger, A. Maciulis, W. W. Daniels, A. R. Torres; L. R. Cardon, S. D. Smith, D. W. Fulker, W. J. Kimberling, B. F. Pennington, J. C. DeFries * Amorphous Stability and Trehalose: C. Colaco, J. Kampinga, B. Roser * Noncoding DNA, Zipf's Law, and Language: A. K. Konopka and C. Martindale SCIENCESCOPE RANDOM SAMPLES 791 807 BOOK REVIEWS 905 The Values of Precision, reviewed by S. Widmalm * Vignettes * Reprints of Books Previously Reviewed PRODUCTS & MATERIALS 915 wnwm_ vab o arw~ Board of Reviewing Editors ..inuwutiwinuuuuminuuinmuusm.& C. Thomas Caskey Dennis W. Choi John M. Coffin F. Fleming Crim Paul J. Crutzen James E. Dahlberg Robert Desimone Bruce F. Eldridge Paul T. Englund Richard G. Fairbanks Douglas T. Fearon Harry A. Fozzard Klaus Friedrich Theodore H. Geballe Roger 1. M. Glass Stephen P. Goff Peter N. Goodfellow Corey S. Goodman Ira Herskowitz Eric F. Johnson Stephen M. Kosslyn Michael LaBarbera Nicole Le Douarin Charles S. Levings Ill Alexander Levitzki Harvey F. Lodish Richard Losick Reinhard Lihrmann Diane Mathis Anthony R. Means Shigetada Nakanishi Roger A. Nicoll Stuart L. Pimm Yeshayau Pocker Dennis A. Powers Ralph S. Quatrano V. Ramanathan Douglas C. Rees T. M. Rice David C. Rubie Erkki Ruoslahti Gottfried Schatz Jozef Schell Ronald H. Schwartz Terrence J. Sejnowski Ellen Solomon Thomas A. Steitz Michael P. Stryker Robert T. N. Tjian Emil R. Unanue Geerat J. Vermeij Bert Vogelstein Arthur Weiss Zena Werb George M. Whitesides Owen N. Witte William A. Wulf SCIENCE * VOL. 268 * 12 MAY 1995 SCIENCE 803 & 889 Functional visualization Frederick W. Alt Don L. Anderson Michael Ashburner Stephen J. Benkovic David E. Bloom Piet Borst Henry R. Bourne Michael S. Brown James J. Bull Kathryn Calame - womcom L 778 on May 17, 2020 http://science.sciencemag.org/ Downloaded from

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Page 1: SCIENCEscience.sciencemag.org/content/sci/268/5212.toc.pdf · ISSN0036-8075 12MAY1995 VOLUME268 NUMBER5212 AMERICAN ASSOCIATIONFORTHE ADVANCEMENTOF SCIENCE NEWS&COMMENT Dispute Splits

ISSN 0036-807512 MAY 1995VOLUME 268NUMBER 5212

AMERICANASSOCIATION FORTHEADVANCEMENT OFSCIENCE

NEWS & COMMENT

Dispute Splits Schizophrenia StudyA Glimpse of an Elusive Quarry

O'Leary Takes Swipe at Bureaucracy

U.K. Tries to Set Priorities With theBenefit of Foresight

Russian Arctic Battles Pipeline Leak

Japan: Chiba's Heavy-Ion AcceleratorBattles Cancer and Critics

792793

794

795

796

797

RESEARCH NEWSnoMAAueA

New Clue to Prostate Cancer Spread 799

Battle Is Joined Over Gamma Bursts 800

Study Unveils Climate Cooling Caused 802by Pollutant Haze

Researchers Get a Sharper Image r 803of the Human Brain

Keeping the Kilo From Gaining Weight 804

Umbilical Cords: Turning Garbage IntoClinical Gold

New Compounds Make Light of Pests

805

806

POLICY FORUM

The World's Forests: Need for aPolicy AppraisalN. Myers

823

PERSPECTIVES--

Neuropeptides, Adenylyl Cyclase, and r 825Memory StorageE. Kandel and T. Abel

r 827A Fixation with FixationG. J. Leigh

ARTICLEFrom Microwave Anisotropies toCosmologyD. Scott, J. Silk, M. White

829

DEPARTMENTSTHIS WEEK IN SCIENCE

EDITORIALDegrees of Uncertainty

781

783

LETTERS 785Impetus for NSF Policy: D. N. Langenberg * WhoSurvived the Cretaceous?: D. H. Janzen * Author-ship Criteria: J. P. Kassirer * EPA and Biotechnol-ogy Regulation: L. R. Goldman * Reading Disabil-ity, Attention-Deficit Hyperactivity Disorder, andthe Immune System: R. P. Warren, J. D. Odell,W. L. Warren, R. A. Burger, A. Maciulis, W. W.Daniels, A. R. Torres; L. R. Cardon, S. D. Smith,

D. W. Fulker, W. J. Kimberling, B. F. Pennington,J. C. DeFries * Amorphous Stability and Trehalose:C. Colaco, J. Kampinga, B. Roser * NoncodingDNA, Zipf's Law, and Language: A. K. Konopkaand C. Martindale

SCIENCESCOPE

RANDOM SAMPLES

791

807

BOOK REVIEWS 905The Values of Precision, reviewed by S. Widmalm *Vignettes * Reprints of Books Previously Reviewed

PRODUCTS & MATERIALS 915

wnwm_ vab o arw~Board of Reviewing Editors ..inuwutiwinuuuuminuuinmuusm.&C. Thomas CaskeyDennis W. ChoiJohn M. CoffinF. Fleming CrimPaul J. CrutzenJames E. DahlbergRobert DesimoneBruce F. EldridgePaul T. EnglundRichard G. Fairbanks

Douglas T. FearonHarry A. FozzardKlaus FriedrichTheodore H. GeballeRoger 1. M. GlassStephen P. GoffPeter N. GoodfellowCorey S. GoodmanIra HerskowitzEric F. Johnson

Stephen M. KosslynMichael LaBarberaNicole Le DouarinCharles S. Levings Ill

Alexander LevitzkiHarvey F. LodishRichard LosickReinhard LihrmannDiane MathisAnthony R. Means

Shigetada NakanishiRoger A. NicollStuart L. PimmYeshayau PockerDennis A. PowersRalph S. QuatranoV. RamanathanDouglas C. ReesT. M. RiceDavid C. Rubie

Erkki RuoslahtiGottfried SchatzJozef SchellRonald H. SchwartzTerrence J. SejnowskiEllen SolomonThomas A. SteitzMichael P. StrykerRobert T. N. TjianEmil R. Unanue

Geerat J. VermeijBert VogelsteinArthur WeissZena WerbGeorge M. WhitesidesOwen N. WitteWilliam A. Wulf

SCIENCE * VOL. 268 * 12 MAY 1995

SCIENCE

803 & 889Functional visualization

Frederick W. AltDon L. AndersonMichael AshburnerStephen J. BenkovicDavid E. BloomPiet BorstHenry R. BourneMichael S. BrownJames J. BullKathryn Calame

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Page 2: SCIENCEscience.sciencemag.org/content/sci/268/5212.toc.pdf · ISSN0036-8075 12MAY1995 VOLUME268 NUMBER5212 AMERICAN ASSOCIATIONFORTHE ADVANCEMENTOF SCIENCE NEWS&COMMENT Dispute Splits

aCOVER

This skeleton of a Late Triassic turtle (210 million years along with those from Northern Hemisphere sites sug-ago) from Argentina extends the South American fossil gest that turtles were a taxonomically and ecologicallyrecord of turtles by 60 million years and provides the diverse group by the Late Triassic. The shell is 55basis for a new interpretation of basal turtle relation- centimeters long from front to back. See page 855.ships and the origin of living groups. This new taxon [Photo: G. W. Rougier]

RESEARCH ARTICLEConversion of Xenopus Ectoderm 836into Neurons by NeuroD, a BasicHelix-Loop-Helix Protein

J. E. Lee, S. M. Hollenberg, L. Snider, D. L.Turner, N. Lipnick, H. Weintraub

REPORTS --------Aligned Carbon Nanotube Films: 845Production and Optical and ElectronicPropertiesW. A. de Heer, W. S. Bacsa, A. Chatelain, T.Gerfin, R. Humphrey-Baker, L. Forro, D. Ugarte

Phonons Localized at Step Edges:A Route to Understanding Forces atExtended Surface DefectsL. Niu, D. J. Gaspar, S. J. Sibener

Seismic Evidence for an EarthquakeNucleation PhaseW. L. Ellsworth and G. C. Beroza

847

851

Late Triassic Turtles from South America 855G. W. Rougier, M. S. de la Fuente, A. B. Arcucci

Serpentine Stability to Mantle Depthsand Subduction-Related MagmatismP. Ulmer and V. Trommsdorff

Dinitrogen Cleavage by aThree-Coordinate Molybdenum(III)ComplexC. E. Laplaza and C. C. Cummins

858

F 861

CD1 Recognition by Mouse NK1+ T 863LymphocytesA. Bendelac, 0. Lantz, M. E. Quimby, J. W.Yewdell, J. R. Bennink, R. R. Brutkiewicz

Identification and Characterization of a 866Prostaglandin TransporterN. Kanai, R. Lu, J. A. Satriano, Y. Bao, A. W.Wolkoff, V. L. Schuster

A Neuropeptide Gene Defined by theDrosophila Memory Mutant amnesiacM. B. Feany and W. G. Quinn

0 869

Control of Proton Sensitivity of the 873NMDA Receptor by RNA Splicing andPolyaminesS. F. Traynelis, M. Hartley, S. F. Heinemann

Gene Trap Tagging of PROLIFERA, 877an Essential MCM2-3-5-Like Gene inArabidopsis

P. S. Springer, W. R. McCombie, V. Sundaresan,R. A. Martienssen

Role of the Chaperone Protein Hsp104 in 880Propagation of the Yeast Prion-LikeFactor [psi+]Y. O. Chemoff, S. L. Lindquist, B.-i. Ono,S. G. Inge-Vechtomov, S. W. Liebman

KAI1, a Metastasis Suppressor Gene r 884for Prostate Cancer on HumanChromosome lip1 1.2J.-T. Dong, P. W. Lamb, C. W. Rinker-Schaeffer, J. Vukanovic, T. Ichikawa, J. T.Isaacs, J. C. Barrett

Long-Range Motional Restrictions in aMultidomain Zinc-Finger Protein fromAnisotropic TumblingR. Brfischweiler, X. Liao, P. E. Wright

886

Borders of Multiple Visual Areas in r 889Humans Revealed by Functional MagneticResonance ImagingM. I. Sereno, A. M. Dale, J. B. Reppas, K. K.Kwong, J. W. Belliveau, T. J. Brady, B. R.Rosen, R. B. H. Tootell

TECHNICAL COMMENTS I

Evaluating Turnover in Tropical ForestsD. Sheil; 0. Phillips

894

: AAAS Board of Directors PI Indicates accompanying featureFrancisco J. Ayala Anna C. Roosevelt M SCIENCE (ISSN 0036-8075) i8 published weekly on Friday, except Change of address: allow 6 weeks, giving old and new addresses and 11-digit

Retiring President, Alan Schriesheim the last week In December, by the American Association for the Ad- account number. Postmaster: Send change of address to Science, P.O. BoxChairman Jean E. Taylor vancement of Science, 1333 H Street, NW, Washington, DC 20005. Second- 2033, Marion, OH 43305-2033. Single copy sales: $7.00 per issue prepaid in-

Rita R. Colwell Chang-Lin Tien class postage (publication No. 484460) paid at Washington, DC, and additional cludes surface postage; bulk rates on request. Authorization to photocopyPresident Nancy S. Wexler mailing offices. Copyright © 1995 by the American Association for the Advance- material for internal or personal use under circumstances not falling within the fair

Jane Lubchenco ment of Science. The title SCIENCE is a registered trademark of the AAAS. use provisions of the Copyright Act is granted by AAAS to libraries and otherPresident-elect Domestic individual membership and subscription (51 issues): $97 ($50 allocated users registered with the Copyright Clearance Center (CCC) Transactional

William.. Golden to subscription). Domestic institutional subscription (51 issues): $228. Foreign Reporting Service, provided that the base fee of $1 per copy plus $0.10 perwAiliam T. Golden postage extra: Mexico, Caribbean (surface mail) $53; other countries (air page is paid directly to CCC, 27 Congress Street, Salem, MA 01970. TheWilliam A. Lester Jr. Treasurer assist delivery) $93. First class, airmail, student and emeritus rates on re- identification code for Science is 0036-8075/83 $1 + .10. Science is indexedSimon A. Levin Richard S. Nicholson quest. Canadian rates with GST available upon request, GST #1254 88122. in the Reader's Guide to Periodical Literature and in several specializedMichael J. Novacek Executive Officer Printed in the U.S.A. indexes.

SCIENCE * VOL. 268 * 12 MAY 1995

836Before and after neuroD

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