issues in inorganic synthesis. ligand synthesis in naoh ph ~11 meoh 20 h or so solvent : ethylene...
TRANSCRIPT
Issues in Inorganic Synthesis
Ligand synthesis
in NaOH pH ~11
MeOH
20 h or so
Solvent : ethylene glycol
Porphyrin substituents on heme in hemoglobin
Metallation of porphyrin
How do you know when the reaction is done?
Anything change at Fe?
Molybdenum Reactions. List them and conditions
MoOCl2detc2
Mo2O3detc4
MoOS2detc2
MoOdetc2
Fe and Ru Reactions. List them and conditions
FeCl(porphyrin)
Ru(bpy)2(L-pterin)
Mechanism:
an advertisement
What’s the difference between pictures A and B?
A Bfrom X-ray crystallography from Chem 3D; “guessed” structure
X-ray Crystallography: the closest we can get to photographing our molecules!
• single crystal (not a powder or many tiny crystals)• periodic array of atoms symmetrically oriented• produces accurate (almost) bond distances and bond angles
• The method:• see U.Penn X-ray Facility• see on-line X-ray Course• see illustration of Space Group Symmetry• one of my old structures (on Cu)
A single crystal structure of a Mo molecule from my lab:
Who wants to go see it done?