IVF and PGD

In Vitro Fertilization

First test tube baby – Louise Brown - 1978

According to CDC’s 2010 ART Success Rates, 147,260* ART cycles were performed at 443 reporting clinics in the United States during 2010, resulting in 47,090 live births.

There are 5 clinics who do ART’s in the Kansas City area.

STEPS OF IVF 1. ovarian

hormonal stimulation

2. retrieval of egg

3.Fertilization

ICSI – 66%

4. Selection of embryos for transfer

5. Transfer of embryos

Embryos not transferred are destroyed or frozen in liquid nitrogen - 50% death rate in thawing process

US Average IVF Success Rates, 2003-2009, data according to CDC/SART The use

of ARTs doubles the risk of birth defects

Selective reduction

• 2-3 embryos are usually introduced into the uterus.

• If the parents only want one child, but more embryos implant, many choose selective reduction. This has become a commonplace procedure, even for those who conceive naturally.

• A potassium chloride solution is injected into the baby’s heart, he dies, and then later is born with the other baby.

PGD One cell is removed from the

embryo. Genetic analysis of its DNA is

done. Embryos who have the desired

traits are introduced into the mother’s uterus.

Undesirable embryos are destroyed or used for research purposes.