january 15-16 translational symposium: 2015 and drug … filecalogera simonaro (dggs-ismms) silvana...
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TRANSLATIONAL SYMPOSIUM:ACCELERATING THERAPEUTIC DEVELOPMENTAND DRUG DISCOVERY
Biological Sciences FacultyPonti�cia Universidad Católica de ChilePortugal # 49
January 15-16
Auditorium B201
Speakers & Moderators
REGISTRATION AND INFORMATION:Dra. Alejandra Alvarez ([email protected])Dra. Silvana Zanlungo ([email protected])
223543833 – 3826-2926 –3734
Alejandra Alvarez (FCB-UC)
Rommy von Bernhardi (FM-UC)Enrique Brandán (FCB-UC)
Andres Dulcey (NCATS-NIH)
Marc Ferrer (NCATS-NIH)
Alfonso González (FM-FCB-UC)
Nibaldo Inestrosa (FCB-UC)
Alexis Kalergis (FCB-UC)
Soledad Matus (FM-UCH)
Samarjit Patnaik (NCATS-NIH)
Edward Schuchman (DGGS-ISMMS)
Calogera Simonaro (DGGS-ISMMS)
Silvana Zanlungo (FM-UC)
2015
R&D WEB WORKSHOP PROGRAM
UC Innovation Center Anacleto AngeliniPonti�cia Universidad Católica de ChileAv. Vicuña Mackenna 4860, Macul.
Juan Marugan (NCATS-NIH)
Yiannis Ioannou (DGGS-ISMMS)
Elisabeth Ottinger (NCATS)
Lili Portilla (NCATS)
CARE
FONDEFFondo de Fomento al DesarrolloCientí�co y Tecnológico
FONDECYTFondo Nacional de DesarrolloCientí�co y Tecnológico
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Free assistance
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TRANSLATIONAL SYMPOSIUM:ACCELERATING THERAPEUTIC DEVELOPMENTAND DRUG DISCOVERY
Biological Sciences FacultyPonti�cia Universidad Católica de ChilePortugal # 49
January 15-16
Auditorium B201
Speakers & Moderators
REGISTRATION AND INFORMATION:Dra. Alejandra Alvarez ([email protected])Dra. Silvana Zanlungo ([email protected])
223543833 – 3826-2926 –3734
Alejandra Alvarez (FCB-UC)
Rommy von Bernhardi (FM-UC)
Enrique Brandán (FCB-UC)
Andres Dulcey (NCATS-NIH)
Marc Ferrer (NCATS-NIH)
Alfonso González (FM-FCB-UC)
Nibaldo Inestrosa (FCB-UC)
Alexis Kalergis (FCB-UC)
Soledad Matus (FM-UCH)
Samarjit Patnaik (NCATS-NIH)
Edward Schuchman (DGGS-ISMMS)
Calogera Simonaro (DGGS-ISMMS)
Silvana Zanlungo (FM-UC)
2015
R&D WEB WORKSHOP PROGRAM
UC Innovation Center Anacleto AngeliniPonti�cia Universidad Católica de ChileAv. Vicuña Mackenna 4860, Macul.
Juan Marugan (NCATS-NIH)
Yiannis Ioannou (DGGS-ISMMS)
Elisabeth Ottinger (NCATS)
Lili Portilla (NCATS)
O
OOH
O
O
O
OH
O
Free assistanceO
OO
H
O
January 15
LECTURES PROGRAM: Auditorium B201. Biological Sciences Faculty, UC
9:00-9:15 Inauguration Juan Larraín, Research Vice President, UC.
Session I Chair: Silvana Zanlungo, Medicine School, UC.
9:15-10:00 Large Scale Pro�ling of Pharmacological Responses: A Screening Platform for the Discovery
of Combination Therapies. Marc Ferrer, NCATS, NIH.
10:00-10:30 Modeling cancer drugs based on protein tra�cking.
Alfonso González, Faculty of Biological Sciences, Medicine School, CARE, UC.
10:30-11:00 Co�ee Break
11:00-11:30 Fundamentals on G-Protein Coupled Receptors and D2-Dopamine Receptor Modulation.
Andres Dulcey, NCATS, NIH.
11:30-12:00 Searching for Therapeutic Approaches to Skeletal Muscle Repair and Healing.
Enrique Brandán, Faculty of Biological Sciences, CARE, UC.
12:00-12:30 Searching and Identi�cation of c-Abl Inhibitors for Alzheimer Disease Treatment.
Alejandra Alvarez, Faculty of Biological Sciences, CARE, UC.
12:30-13:00 Open Discussion
13:00-15:00 Lunch
Session II Chair: Rommy von Bernhardi, Medicine School, UC.
15:00-15:30 Modulating the immunological synapse to enhance pathogen immunity
and reduce detrimental in�ammation for high burden diseases.
Alexis Kalergis, Faculty of Biological Sciences, IMII, UC.
15:30-16:00I In�ammatory Mechanisms and the Use of Pentosan Polysulfate in the Mucopolysaccharidoses.
Calogera Simonaro, Department of Genetics & Genomic Sciences, ISMMS.
16:00-16:30 Targeting ER stress signaling in ALS. Soledad Matus. Faculty of Medicine, BNI, UCH.
16:30–17:00 Co�ee Break
17:00-17:30 Discovery and Progression of Non-Inhibitory Chaperones for Gaucher
Disease. Samarjit Patnaik, National Center for Advancing Translational
Sciences, NCATS, NIH.
17:30- 18:00 The Translational Biology of Acid Sphingomyelinase & Acid Ceramidase:
The Road to New Therapies. Edward H. Schuchman,
Department of Genetics & Genomic Sciences, ISMMS.
18:00-18:30 Open Discussion & Concluding Remarks,
Dr. Nibaldo Inestrosa, Faculty of Biological Sciences, CARE, UC.
18:30-20:00 Cocktail
January 16
R&D WEB WORKSHOP PROGRAM: 2015 UC Innovation Center - Anacleto Angelini
Chair: Juan Marugan, NCATS, NIH.
9:30-10:00 Development and Commercialization of Enzymatic Replacement for Fabry Disease.
Yiannis A. Ioannou, Genetics & Genomic Sciences, ISMMS.
10:00-10:30 Intellectual Property and Transfer Technology Aspects in Translation.
Lili Portilla, NCATS, NIH.
10:30-11:00 Preclinical Development, Natural History Studies, Development of Clinical Protocols,
IND Filling and First in Humans. Elisabeth Ottinger, NCATS, NIH.
11:00-11:30 Co�ee.
CARE
FONDEFFondo de Fomento al DesarrolloCientí�co y Tecnológico
FONDECYTFondo Nacional de DesarrolloCientí�co y Tecnológico