jared ray mays, ph.d.faculty.augie.edu/~jmays/mays/cv_190107.pdfjared ray mays, ph.d. contact...

Jared Ray Mays, Ph.D.

CONTACT INFORMATION

Augustana University Tel: (605) 274-4815

Department of Chemistry Fax: (605) 274-4492

2001 S. Summit Avenue, FSC 325 Mobile: (210) 248-8462

Sioux Falls, SD 57197 Email: [email protected]

EDUCATION AND EMPLOYMENT

2015 – Current Augustana University (Augustana College, pre-2015) – Sioux Falls, SD

Associate Professor of Chemistry

2009 – 2015 Augustana College – Sioux Falls, SD

Assistant Professor of Chemistry

2007 – 2009 The University of Kansas – Lawrence, KS

Postdoctoral Research Associate, Medicinal Chemistry

2003 – 2007 The University of Wisconsin – Madison, WI

Ph.D., Pharmaceutical Sciences

1999 – 2003 Gustavus Adolphus College – St. Peter, MN

B.A., Chemistry, Biochemistry

TEACHING EXPERIENCE

2009 – Current Augustana University – Sioux Falls, SD

Assistant/Associate Professor of Chemistry

Courses Taught (Lecture and Laboratory)

– Chemistry 120: Introduction to Chemistry (2009-2012)

– Chemistry 120: Accelerated General Chemistry (2013-Current)

– Chemistry 145: Survey of Organic and Biochemistry

– Chemistry 201: Organic Chemistry I

– Chemistry 202: Organic Chemistry II

– Chemistry 305: Biochemistry

– Chemistry 330: Biochemistry & Medicinal Chemistry (2009-2016)

– Chemistry 330: Medicinal Chemistry (2017-Current)

– Chemistry 399: Independent Study

Courses Taught (Lecture)

– General Education 097: New Student Seminar

– Civitas 202: Pertinence

– General Education 492: Senior Capstone

– Civitas 395: Vocation Project


Department Teaching Assistant (Eight Laboratory Sections)

– Biology 102: Organismal Biology

– Chemistry 141: Organic Chemistry I

– Chemistry 251: Organic Chemistry II

– Chemistry 255: Biochemistry I

– Chemistry 370: Quantitative Analysis

Laboratory Assistant

– Prepared unknown samples for use in Quantitative Analysis laboratory

Chemistry Department Tutor

– Tutored students in General, Organic, Inorganic, Analytical, Bio-, and Physical

Chemistries

– Co-head chemistry department tutor for 2002 – 2003 school year

RESEARCH EXPERIENCE

2009 – Current Augustana University – Sioux Falls, SD

Principle Investigator and Research Advisor

Research Assistants: Michael Amolins

Undergraduate Research Assistants: Kayla Vastenhout, Jordan Clark, Cody Lensing,

Ruthellen Tornberg, Joseph Keppen, Zachary Erickson, Amanda Johnson, Taylor

Yseth, Michaela Bunde, Ethan Pauley, Genevieve Tillotson, Sarah Fisher, Collin

Noldner, Justin Brown, John Klecker, Ellen Voigt, Chase Klingaman, Matt Wagner,

Carl Lang, Claire Fanta, Katie Tlusty, Marie Anderson, Eleanor Ronning, Alexa Snyder

Projects

– Preparation of non-natural isothiocyanate libraries and differential evaluation using

antiproliferation and ARE-induction assays

– Construction of non-natural glucosinolates

– Development of reverse-phase HPLC and UV-Vis methods to assess myrosinase-

dependent hydrolysis kinetics

– Exploration of methods to generate isothiocyanates from non-glucosinolates

– Preparation of intermediates in the phenolic glucosinolate biosynthetic pathway for

use in flux control studies

2007 – 2009 The University of Kansas – Lawrence, KS

Research Advisor: Brian S. J. Blagg, Ph.D.

Undergraduate Research Assistants: Stephanie Hill, Justin Moyers

Projects

– Preparation and evaluation of positional and directional isomers of the

amidocoumarin scaffold

– Syntheses and biological evaluation of chimeric flavone/isoflavone Hsp90 inhibitors

incorporating elements of novobiocin and derrubone

– Construction and biological assessment of quinoline- and naphthalene-derived

analogs of novobiocin to probe structure/activity relationships for C-terminal Hsp90

inhibition

Responsibilities

– Oversee training and mentoring for new postdoctoral associates and graduate students

– Maintain Blagg group chemical inventory and chemical/biological supply orders

2003 – 2007 The University of Wisconsin – Madison, WI

Research Advisor: Scott R. Rajski, Ph.D.

Undergraduate Research Assistants: Anni Zhao, James Avruch

Ph.D. Thesis: Synthetic and Biological Studies Directed at the Development of New

HDAC-Inhibiting Prodrugs

Projects

– Synthesis of non-natural glucosinolates and investigation of myrosinase-dependent

bioactivities

– Construction of analogs based on the bioactive metabolite of sulforaphane to study its

structure-activity relationships

– Synthesis of a structure-diversified isothiocyanate panel and assessment of compound

cytotoxicity relative to sulforaphane

– Synthesis of structurally-simplified cyclic disufides as bio-functional mimics of the

histone deacetylase inhibitor FK-228

– Semi-synthesis of S-adenosylhomocysteine and (S)-perillyl alcohol analogs

Responsibilities

– Instrument maintenance for Rajski group HPLC and lyophilizer

– Maintenance of School of Pharmacy anhydrous solvent-dispensing system, 400 MHz

Varian Gemini NMR Spectrometer, and 500 MHz Varian NMR Spectrometer


Research Advisor: Gretchen E. Hofmeister, Ph.D.

Projects

– Syntheses and resolution of chiral bisphenol and trisphenol ligands for use in

enantioselective reactions with Ti(IV)

PUBLICATIONS AND PATENTS

**Undergraduate authors are designated in italics.

1. Anderson, R. H.; Lensing, C. J.; Forred, B. J.; Amolins, M. W.; Aegerter, C. L.; Vitiello, P. F.; Mays, J.

R. “Differentiating antiproliferative and chemopreventive modes of activity for electron-deficient aryl

isothiocyanates against human MCF-7 cells. ChemMedChem, 2018, 13, 1695–1710.

2. Klingaman, C. K.; Wagner, M. J.; Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Noldner, C. J.; Mays, J.

R. “HPLC-based kinetics assay facilitates analysis of systems with multiple reaction products and

thermal enzyme denaturation. Anal. Biochem. 2017, 516, 37–47.

3. Klingaman, C. K.; Wagner, M. J.; Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Noldner, C. J.; Mays, J.

R. “Synthesis and spectral characterization of 2,2-diphenylethyl glucosinolate and HPLC-based reaction

progress curve data for the enzymatic hydrolysis of glucosinolates by Sinapis alba myrosinase. Data in

Brief, 2016, 10, 151–181.

4. Vastenhout, K. J.; Tornberg, E. H.; Johnson, A. L.; Amolins, M. W.; Mays, J. R. High performance

liquid chromatography-based method to evaluate kinetics of glucosinolate hydrolysis by Sinapis alba

myrosinase. Anal. Biochem. 2014, 465, 105–113.

5. Earl, G. W.; Eichler, B. E.; Moore, B. E.; Weisshaar, D. E.; Duffy-Matzner, J. L.; Mays, J. R.; Dey, B.

K. Developing and sustaining a research program at a traditionally undergraduate liberal arts college:

Research, it’s our thing! Experiences in establishing a research culture at Augustana College, Sioux

Falls, SD. In Developing and Maintaining a Successful Undergraduate Research Program; ACS

Symposium Series 1156; American Chemical Society: Washington, DC, 2014; 61–80.

6. Mays, J. R.; Duffy-Matzner, J. L. Revamping a second semester organic chemistry course to meet the

new ACS biochemistry requirements. In Advances in Teaching Organic Chemistry; Duffy-Matzner, J.

L., Pacheco, K. A. O., Eds.; ACS Symposium Series 1108; American Chemical Society: Washington,

DC 2012; pp 177–183.

7. Mays, J. R.; Hill, S. A.; Moyers, J. T.; Blagg, B. S. J. The synthesis and evaluation of flavone and

isoflavone chimeras of novobiocin and derrubone. Bioorg. Med. Chem. 2010, 18, 249–266.

8. Mays, J. R.; Donnelly, A. C.; Burlison, J. A.; Nelson, J. T.; Vielhauer, G.; Holzbeierlein, J.; Blagg, B.

S. J. The design, synthesis and evaluation of coumarin ring derivatives of the novobiocin scaffold that

exhibit anti-proliferative activity. J. Org. Chem. 2009, 73, 8901–8920.

9. Mays, J. R.; Weller, R. L.; Sarfaraz, S.; Mukhtar, H.; Rajski, S. R. Identification, synthesis and

enzymology of nonnatural glucosinolate chemopreventive candidates. ChemBioChem. 2008, 9, 729–

747.

10. Mays, J. R.; Rajski, S.R. Preparation of isothiocyanates and glucosinolates as antitumor agents. 2008,

International Patent WO 2008008954.

11. Mays, J. R.; Restituyo, J. A.; Katzenberger, R.; Wassarman, D. A.; Rajski, S. R. Cyclic disulfides as

functional mimics of the histone deacetylase inhibitor FK-228. Tetrahedron Lett. 2007, 48, 4579–4583.

PRESENTATIONS

**Undergraduate authors are designated in italics, presenting author(s) for posters and seminars are underlined.

Augustana University – Sioux Falls, SD

1. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Fisher, S. E.; Mays, J. R. “Synthesis of 4-

(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” General

Organic Poster Session, 53rd American Chemical Society Midwest Regional Meeting, Ames, IA;

October 23, 2018.

2. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Evaluation of the Antiproliferation

Effects of Glucosinolates Against Humans MCF-7 Cells.” Undergraduate Poster Session, 53rd

American Chemical Society Midwest Regional Meeting, Ames, IA; October 22, 2018.

3. Anderson, M. A.; Ronning, E. K.; Snyder, A. A.; Mays, J. R. “Nitronate Syntheses of 4-

(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate and Evaluation of Antiproliferation

Effects of Glucosinolates on MCF-7 Cells.” Chemistry/Physics Seminar Series, Augustana University,

Sioux Falls, SD; October 19, 2018.


(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” 2018 Sioux

Valley ACS Undergraduate Research Symposium, Augustana University, Sioux Falls, SD; September

22, 2018. (Awarded 1st place in the judged poster competition).


Effects of Glucosinolates Against Humans MCF-7 Cells.” 2018 Sioux Valley ACS Undergraduate

Research Symposium, Augustana University, Sioux Falls, SD; September 22, 2018.


(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” Undergraduate

Summer Research Poster Session, Augustana University, Sioux Falls, SD; September 19, 2018.


Effects of Glucosinolates Against Humans MCF-7 Cells.” Undergraduate Summer Research Poster

Session, Augustana University, Sioux Falls, SD; September 19, 2018.


(Methylsulfinyl)benzyl and 3-Pyridylmethyl Glucosinolate via the Nitronate Pathway.” Undergraduate

Research Symposium, Pierre, SD; July 25-26, 2018.


Effects of Glucosinolates Against Humans MCF-7 Cells.” Undergraduate Research Symposium,

Pierre, SD; July 25-26, 2018.

10. Fanta, C. C.; Tlusty, K. J.; Johnson, A. J.; Mays, J. R. “Synthesis and Evaluation of Substituted-Biaryl

Isothiocyanates.” Arthur Olsen Student Research Symposium 2018, Sioux Falls, SD; April 21, 2018.

11. Lang, C. W.; Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Generation of Benzyl Isothiocyanate via

Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Arthur Olsen Student Research Symposium

2018, Sioux Falls, SD; April 21, 2018.


Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Chemistry/Physics Seminar Series,

Augustana University, Sioux Falls, SD; March 2, 2018.


Isothiocyanates.” Biochemistry Poster Session, 52nd American Chemical Society Midwest Regional

Meeting, Lawrence, KS; October 18-20, 2017.


Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Biochemistry Poster Session, 52nd American

Chemical Society Midwest Regional Meeting, Lawrence, KS; October 18-20, 2017.


Isothiocyanates.” Chemistry/Physics Seminar Series, Augustana University, Sioux Falls, SD; October

6, 2017.


Isothiocyanates.” 2017 Sioux Valley ACS Undergraduate Research Symposium, Augustana

University, Sioux Falls, SD; September 29, 2017. (Awarded 3rd place in the judged poster

competition).


Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” 2017 Sioux Valley ACS Undergraduate

Research Symposium, Augustana University, Sioux Falls, SD; September 29, 2017. (Awarded 2nd

place in the judged poster competition).


Isothiocyanates.” Undergraduate Summer Research Poster Session, Augustana University, Sioux Falls,

SD; September 13, 2017.


Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Undergraduate Summer Research Poster

Session, Augustana University, Sioux Falls, SD; September 13, 2017.


Isothiocyanates.” Undergraduate Research Symposium, Pierre, SD; August 2-3, 2017. (Awarded 2nd

place in the judged poster competition).


Photolysis of an ortho-Nitrobenzyl-Protected Analogue.” Undergraduate Research Symposium, Pierre,

SD; August 2-3, 2017.

22. Mays, J. R. “Differentiating antiproliferative and chemopreventive modes of activity for electron-

deficient aryl isothiocyanates against human MCF-7 cells.” Eastern South Dakota Research

Symposium, Sanford Center, Sioux Falls, SD; May 31, 2017.

23. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Enzymatic Hydrolysis of 2,2-Diphenylethyl

Glucosinolate.” Arthur Olsen Student Research Symposium 2017, Sioux Falls, SD; April 16, 2017.

24. Mays, J. R. “Differentiating antiproliferative and chemopreventive modes of activity for electron-

deficient aryl isothiocyanates against human MCF-7 cells.” General Poster Session, Division of

Medicinal Chemistry, 253rd ACS National Meeting, San Francisco, CA; April 2–6, 2017.

25. Mays, J. R. “Developing an interdisciplinary medicinal chemistry undergraduate research program at a

small, private, liberal arts university.” Advancing Undergraduate Research Symposium, Division of

Chemical Education, 253rd ACS National Meeting, San Francisco, CA; April 2–6, 2017.


Glucosinolate.” Undergraduate Research Poster Session, Division of Chemical Education, 253rd ACS

National Meeting, San Francisco, CA; April 2–6, 2017.


Glucosinolate.” Undergraduate Research Symposium, Augustana University, Sioux Falls, SD;

September 24, 2016.


Glucosinolate.” Undergraduate Summer Research Poster Session, Augustana University, Sioux Falls,


29. Klingaman, C. A.; Wagner, M. J.; Mays, J. R. “Glucotropaeolin and non-natural substrate 2,2-

diphenylethyl glucosinolate demonstrate consistent outcomes of hydrolysis by Sinapis alba

myrosinase.” Chemistry/Physics Department Seminar Series, Augustana University, Sioux Falls, SD;

September 16, 2016.


Glucosinolate.” Undergraduate Research Symposium, Pierre, SD; July 31-August 1, 2016.


Glucosinolate.” Arthur Olsen Student Research Symposium 2016, Sioux Falls, SD; April 16, 2016.


Glucosinolate.” Current Topics in Biochemistry Poster Session, 251st ACS National Meeting, San

Diego, CA; March 13–17, 2016.


Glucosinolate.” Biochemistry Poster Session, 50th American Chemical Society Midwest Regional

Meeting, St. Joseph, MO; October 21-23, 2015.


Glucosinolate.” Undergraduate Summer Research Poster Session, Augustana University, Sioux Falls,

SD; October 10, 2015.


Glucosinolate.” Chemistry Department Seminar Series, Augustana University, Sioux Falls, SD;

October 2, 2015.


Glucosinolate.” Undergraduate Chemistry Research Symposium, Graduate Education and Applied

Research Center, University of South Dakota, Sioux Falls, SD; September 26, 2015.


Glucosinolate.” Biomedical Research Infrastructure Network Convocation, The University of South

Dakota, Vermillion, SD; August 7, 2015.


Glucosinolate.” 2015 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD;

August 6, 2015.


Glucosinolate.” 2015 South Dakota Undergraduate Research Symposium, Pierre, SD; July 30, 2015.

40. Brown, J. R.; Klecker, J. B.; Pauley, E. H.; Mays, J. R. “Preparation of 2,2-Diphenylethyl

Glucosinolate.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls,

SD; May 1, 2015.

41. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.” Poster

Presentation, Arthur Olsen Student Research Symposium, Sioux Falls, SD; April 18, 2015.


Glucosinolate.” Poster Presentation, Arthur Olsen Student Research Symposium, Sioux Falls, SD;

April 18, 2015.

43. Fisher, S. E.; Mays, J. R. “Fighting Cancer with Broccoli.” Arthur Olsen Student Research

Symposium, Sioux Falls, SD; April 18, 2015.

44. Mays, J. R. “Synthesis of Chemopreventive Glucosinolates: A Nitronate Approach” RSA Luncheon,

Augustana College, Sioux Falls, SD; April 8, 2015.

45. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Photolysis of Non-Glucosinolates to form ITCs.” Chemistry

and Physics Department Seminar Series, Augustana College, Sioux Falls, SD; March 27, 2015.

46. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.”

Undergraduate Research in Medicinal Chemistry Poster Session, 249th ACS National Meeting,

Denver, CO; March 22–26, 2015.

47. Fisher, S. E.; Mays, J. R. “Fighting Cancer With Broccoli.” Chemistry and Physics Department

Seminar Series, Augustana College, Sioux Falls, SD; February 6, 2015.

48. Fisher, S. E.; Mays, J. R. “Exploration of the Nitronate Synthetic Pathway of Glucosinolates.” Poster

Session, 49th American Chemical Society Midwest Regional Meeting, Columbia, MO; November 12-

14, 2014.

49. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.” Poster

Session, 49th American Chemical Society Midwest Regional Meeting, Columbia, MO; November 12-

14, 2014.


Glucosinolate.” Poster Session, 49th American Chemical Society Midwest Regional Meeting,

Columbia, MO; November 12-14, 2014.

51. Fisher, S. E.; Mays, J. R. “Exploration of the Nitronate Synthetic Pathway of Glucosinolates.”

Undergraduate Chemistry Research Symposium, Graduate Education and Applied Research Center,

University of South Dakota, Sioux Falls, SD; September 20, 2014. (Awarded 2nd place in the judged

poster competition).


Undergraduate Chemistry Research Symposium, Graduate Education and Applied Research Center,

University of South Dakota, Sioux Falls, SD; September 20, 2014.


Glucosinolate.” Undergraduate Chemistry Research Symposium, Graduate Education and Applied

Research Center, University of South Dakota, Sioux Falls, SD; September 20, 2014.

54. Fisher, S. E.; Mays, J. R. “Exploration of the Nitronate Synthetic Pathway of Glucosinolates.”

Undergraduate Summer Research Poster Session, Augustana College, Sioux Falls, SD; September 17,

2014.


Undergraduate Summer Research Poster Session, Augustana College, Sioux Falls, SD; September 17,

2014.


Glucosinolate.” Undergraduate Summer Research Poster Session, Augustana College, Sioux Falls,


57. Voigt, E. M.; Pauley, E. H.; Mays, J. R. “Preparation and Photolysis of Non-Glucosinolates.” 2014

Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD; August 7, 2014.


Glucosinolate.” 2014 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD;

August 7, 2014.

59. Williams, T.; Seib, L.; Drake, R.; Mays, J. “My ZAB is dying! Exact mass determinations of ESI

invisible molecules on Qtofs with TAPCI, Toluene Atmospheric Pressure Chemical Ionization.” 62nd

ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD; June 15–19, 2014.

60. Tillotson, G. A.; Amolins, M. A.; Vitiello, P. F.; Mays, J. R. “Synthesis and Evaluation of Nitrile- and

Polyphenyl Isothiocyanates.” Chemistry and Physics Department Seminar Series, Augustana College,

Sioux Falls, SD; April 25, 2014.

61. Fisher, S. E.; Amolins, M. A.; Yseth, T. K.; Clark, J. J.; Vitiello, P. F.; Mays, J. R. “Synthesis and

Evaluation of Novel Non-Natural Isothiocyanates.” Poster Presentation, Augustana College


62. Pauley, E. H.; Mays, J. R. “Preparation of a Photoactive Non-Glucosinolate Precursor to an

Isothiocyanate.” Poster Presentation, Augustana College Symposium, Sioux Falls, SD; April 12, 2014.

63. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Poster Presentation,

Augustana College Symposium, Sioux Falls, SD; April 12, 2014.

64. Mays, J. R. “Glucosinolates: A Tale of Two Syntheses.” RSA Luncheon, Augustana College, Sioux

Falls, SD; March 26, 2014.


Evaluation of Novel Non-Natural Isothiocyanates.” Undergraduate Research in Medicinal Chemistry

Poster Session, 247th ACS National Meeting, Dallas, TX; March 16–20, 2014.


Isothiocyanate.” Undergraduate Research in Medicinal Chemistry Poster Session, 247th ACS National

Meeting, Dallas, TX; March 16–20, 2014.

67. Mays, J. R.; Vastenhout, K. J.; Tornberg, R. H.; Johnson, A. J.; Amolins, M. W. Abstracts of Papers,

247th National Meeting of the American Chemical Society, Dallas, TX, March 16–20, 2014; American

Chemical Society: Washington, DC, 2014.

68. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Chemistry and

Physics Department Seminar Series, Augustana College, Sioux Falls, SD; February 28, 2014.

69. Mays, J. R. “Chemistry and Life as a Chemist.” Boy Scout Chemistry Merit Badge Camp-In,

Washington Pavillion, Sioux Falls, SD; February 8, 2014.


Isothiocyanate.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls,

SD; November 8, 2013.


Evaluation of Novel Non-Natural Isothiocyanates.” Poster Session, 48th American Chemical Society

Midwest Regional Meeting, Springfield, MO; October 26-19, 2013.

72. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Poster Session, 48th

American Chemical Society Midwest Regional Meeting, Springfield, MO; October 26-19, 2013.


Isothiocyanate.” Poster Session, 48th American Chemical Society Midwest Regional Meeting,

Springfield, MO; October 26-19, 2013.


Polyphenyl Isothiocyanates.” Poster Session, 48th American Chemical Society Midwest Regional

Meeting, Springfield, MO; October 26-19, 2013.


Evaluation of Novel Non-Natural Isothiocyanates.” American Chemical Society Sioux Valley Section

Poster Competition, Graduate Education and Applied Research Center, Sioux Falls, SD; September

28, 2013. (Awarded 2nd place in the judged poster competition).

76. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” American Chemical

Society Sioux Valley Section Poster Competition, Graduate Education and Applied Research Center,

Sioux Falls, SD; September 28, 2013.


Isothiocyanate.” American Chemical Society Sioux Valley Section Poster Competition, Graduate

Education and Applied Research Center, Sioux Falls, SD; September 28, 2013.


Evaluation of Novel Non-Natural Isothiocyanates.” Chemistry and Physics Department Seminar

Series, Augustana College, Sioux Falls, SD; September 20, 2013.


Evaluation of Novel Non-Natural Isothiocyanates.” Gilbert Science Center Fall Poster Presentation,

Augustana College, Sioux Falls, SD; September 18, 2013.

80. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Gilbert Science

Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 18, 2013.


Isothiocyanate.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;

September 18, 2013.


Polyphenyl Isothiocyanates.” Gilbert Science Center Fall Poster Presentation, Augustana College,

Sioux Falls, SD; September 18, 2013.


Evaluation of Novel Non-Natural Isothiocyanates.” Biomedical Research Infrastructure Network

Convocation, The University of South Dakota, Vermillion, SD; August 9, 2013.

84. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” Biomedical

Research Infrastructure Network Convocation, The University of South Dakota, Vermillion, SD;

August 9, 2013.


Isothiocyanate.” Biomedical Research Infrastructure Network Convocation, The University of South



Polyphenyl Isothiocyanates.” Biomedical Research Infrastructure Network Convocation, The

University of South Dakota, Vermillion, SD; August 9, 2013.


Evaluation of Novel Non-Natural Isothiocyanates.” 2013 Summer Research Symposium, Sanford

Research, Sioux Falls, SD; August 8, 2013.

88. Noldner, C. J.; Pauley, E. H.; Mays, J. R. “Parallel Syntheses of Glucosinolates.” 2013 Summer

Research Symposium, Sanford Research, Sioux Falls, SD; August 8, 2013.


Isothiocyanate.” 2013 Summer Research Symposium, Sanford Research, Sioux Falls, SD; August 8,

2013.


Polyphenyl Isothiocyanates.” 2013 Summer Research Symposium, Sanford Research, Sioux Falls, SD;

August 8, 2013.

91. Amolins, M. W.; Forred, B. J.; Nagata, S.; Ise, T.; Tornberg, R. H.; Lensing, C. J.; Mays, J. R.;

Vitiello, P. F. “Isothiocyanate-Induced Antioxidant Response: Potential Mechanisms for

Chemoprevention.” 2013 Summer Research Symposium, Sanford Research, Sioux Falls, SD; August

8, 2013.

92. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Oral

Presentation, Augustana College Symposium, Sioux Falls, SD; April 20, 2013.

93. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Isothiocyanates (ITCs): Chemopreventive

and Chemotherapeutic Candidates.” Oral Presentation, Augustana College Symposium, Sioux Falls,

SD; April 20, 2013.

94. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. Poster Presentation, Augustana College


95. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Isothiocyanates (ITCs): Chemopreventive

and Chemotherapeutic Candidates.” Chemistry and Physics Department Seminar Series, Augustana

College, Sioux Falls, SD; April 19, 2013.

96. Tornberg, E. H.; Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.”

Poster Session, 98th Annual Meeting of the South Dakota Academy of Science , Sioux Falls, SD; April

13, 2013. Cancelled due to weather.

97. Johnson, A. L.; Mays, J. R. “Synthesis and Evaluation of Alkyl and Aryl Isothiocyanates as Anticancer

Agents.” Poster Session, 98th Annual Meeting of the South Dakota Academy of Science , Sioux Falls,

SD; April 13, 2013. Cancelled due to weather.


Undergraduate Poster Session, 245th ACS National Meeting, New Orleans, LA; April 7-11, 2013.


Agents.” Undergraduate Poster Session, 245th ACS National Meeting, New Orleans, LA; April 7-11,

2013.

100. Mays, J. R. “Glucosinolates, Isothiocyanates, and Cancer.” Advanced Chemistry Research Course,

Harrisburg, SD; December 12, 2012.

101. Yseth, T. K.; Amolins, M. W.; Clark, J. J.; Mays, J. R. “Synthesis and Evaluation of Methoxy

Isothiocyanates and Sulforaphane Homologs.” Chemistry and Physics Department Seminar Series,

Augustana College, Sioux Falls, SD; November 16, 2012.


Poster Session, 47th American Chemical Society Midwest Regional Meeting, Omaha, NE; October 24-

27, 2012.


Agents.” Poster Session, 47th American Chemical Society Midwest Regional Meeting, Omaha, NE;

October 24-27, 2012. (One of 9 outstanding posters from 94 entries)

104. Bunde, M. M.; Mays, J. R. “Synthesis and Evaluation of Phenoxy Isothiocyanates.” Poster Session,

47th American Chemical Society Midwest Regional Meeting, Omaha, NE; October 24-27, 2012.


Isothiocyanates and Sulforaphane Homologs.” Poster Session, 47th American Chemical Society

Midwest Regional Meeting, Omaha, NE; October 24-27, 2012.


American Chemical Society Sioux Valley Section Poster Competition, Graduate Education and

Applied Research Center, Sioux Falls, SD; September 29, 2012 (Awarded 2nd place in the judged

poster competition).


Agents.” American Chemical Society Sioux Valley Section Poster Competition, Graduate Education

and Applied Research Center, Sioux Falls, SD; September 29, 2012.


Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls, SD; September

14, 2012.


Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 12,

2012.


Agents.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;

September 12, 2012.


Isothiocyanates and Sulforaphane Homologs.” Gilbert Science Center Fall Poster Presentation,

Augustana College, Sioux Falls, SD; September 12, 2012.


Isothiocyanates and Sulforaphane Homologs.” Poster Session, Sanford Research/USD Cancer Biology

Symposium, Sanford Research, Sioux Falls, SD; August 30, 2012.

113. Bunde, M. M.; Mays, J. R. “Synthesis and Evaluation of Phenoxy Isothiocyanates.” South Dakota

Biomedical Research Infrastructure Network Convocation, The University of South Dakota,

Vermillion, SD; August 3, 2012.


Agents.” South Dakota Biomedical Research Infrastructure Network Convocation, The University of

South Dakota, Vermillion, SD; August 3, 2012.


South Dakota Biomedical Research Infrastructure Network Convocation, The University of South


116. Bunde, M. M.; Mays, J. R. “Synthesis and Evaluation of Phenoxy Isothiocyanates.” Poster Session,

2012 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD; August 2, 2012.


Agents.” Poster Session, 2012 Sanford Summer Research Symposium, Sanford Research, Sioux Falls,

SD; August 2, 2012.


Poster Session, 2012 Sanford Summer Research Symposium, Sanford Research, Sioux Falls, SD;

August 2, 2012.


Isothiocyanates and Sulforaphane Homologs.” Poster Session, 2012 Sanford Summer Research

Symposium, Sanford Research, Sioux Falls, SD; August 2, 2012.


Poster Session, 1st Annual It’s All About Science Festival, Sanford Research, Sioux Falls, SD; July 28,

2012.

121. Vastenhout, K.; Mays, J. R. “Synthesis and RP-HPLC Monitored Hydrolysis of Non-Natural

Glucosinolates.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls,

SD; May 11, 2012.


Glucosinolates.” Oral Presentation, Augustana College Symposium, Sioux Falls, SD; April 20-21,

2012.

123. Keppen, J. W.; Clark, J. J.; Mays, J. R. “Synthesis of 3-Pyridylmethyl Glucosinolate from 3-

Pyridylacetonitrile.” Poster Presentation, Augustana College Symposium, Sioux Falls, SD; April 20-

21, 2012.


Poster Presentation, Augustana College Symposium, Sioux Falls, SD; April 20-21, 2012.


Pyridylacetonitrile.” Chemistry and Physics Department Seminar Series, Augustana College, Sioux

Falls, SD; April 20, 2012.


Glucosinolates.” Poster Presentation, 97th South Dakota Academy of Science Annual Meeting,

Vermillion, SD; April 14, 2012.


Pyridylacetonitrile.” Poster Presentation, 97th South Dakota Academy of Science Annual Meeting,

Vermillion, SD; April 14, 2012.


Poster Presentation, 97th South Dakota Academy of Science Annual Meeting, Vermillion, SD; April

14, 2012.


Glucosinolates.” Undergraduate Poster Session, 243rd ACS National Meeting, San Diego, CA; March

25-29, 2012.


Undergraduate Poster Session, 243rd ACS National Meeting, San Diego, CA; March 25-29, 2012.


Chemistry and Physics Department Seminar Series, Augustana College, Sioux Falls, SD; February 17,

2012.


Pyridylacetonitrile.” American Chemical Society Midwest/Great Lakes Joint Regional Meeting,

Organic Chemistry Poster Session, St. Louis, MO; October 26-28, 2011.


Glucosinolates.” American Chemical Society Midwest/Great Lakes Joint Regional Meeting,

Biochemistry Poster Session, St. Louis, MO; October 26-28, 2011. (Awarded best poster in the

biochemistry subcategory)

134. Erickson, Z.; Mays, J. R. “Synthesis of Isothiocyanates with Electron-Deficient Aromatic Rings.”

American Chemical Society Midwest/Great Lakes Joint Regional Meeting, Organic Chemistry Poster

Session, St. Louis, MO; October 26-28, 2011.

135. Mays, J. R. “Glucosinolates, isothiocyanates, and cancer: The story of what we can learn from

broccoli.” RSA Luncheon, Augustana College, Sioux Falls, SD; September 29, 2011.


Pyridylacetonitrile.” American Chemical Society Sioux Valley Section Poster Competition, The

University of South Dakota, Vermillion, SD; September 24, 2011.


Glucosinolates.” American Chemical Society Sioux Valley Section Poster Competition, The

University of South Dakota, Vermillion, SD; September 24, 2011.


American Chemical Society Sioux Valley Section Poster Competition, The University of South

Dakota, Vermillion, SD; September 24, 2011.


Pyridylacetonitrile.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls,



Glucosinolates.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;

September 14, 2011.


Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 14,

2011.


Pyridylacetonitrile.” Poster Session, 2nd Annual Student Research Symposium at Sanford

Research/USD, Sioux Falls, SD; August 4, 2011.


Glucosinolates.” Poster Session, 2nd Annual Student Research Symposium at Sanford Research/USD,

Sioux Falls, SD; August 4, 2011.


Poster Session, 2nd Annual Student Research Symposium at Sanford Research/USD, Sioux Falls, SD;

August 4, 2011.


Poster Session, 2nd Annual Student Research Symposium at Sanford Research/USD, Sioux Falls, SD;

August 4, 2011.


Pyridylacetonitrile.” South Dakota Biomedical Research Infrastructure Network Convocation, The

University of South Dakota, Vermillion, SD; July 29, 2011.


Glucosinolates.” South Dakota Biomedical Research Infrastructure Network Convocation, The



Poster Session, Northern Plains Undergraduate Research Conference Symposium, Ponca State Park,

Ponca, NE; July 29, 2011.


Poster Session, Northern Plains Undergraduate Research Conference Symposium, Ponca State Park,

Ponca, NE; July 29, 2011.


Glucosinolates.” Poster Session, 96th Annual Meeting of the South Dakota Academy of Science,

Oacoma, SD; April 9, 2011.

151. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” Poster Session,

96th Annual Meeting of the South Dakota Academy of Science, Oacoma, SD; April 9, 2011.

152. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Augustana College



Glucosinolates.” Undergraduate Poster Session, 241st ACS National Meeting, Anaheim, CA; March

27-31, 2011.

154. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Undergraduate

Poster Session, 241st ACS National Meeting, Anaheim, CA; March 27-31, 2011.


Glucosinolates.” Chemistry and Physics Departmental Seminar Series, Augustana College, Sioux

Falls, SD; December 14, 2010.

156. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Chemistry and

Physics Departmental Seminar Series, Augustana College, Sioux Falls, SD; November 19, 2010.

157. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” American

Chemical Society Midwest Regional Meeting, Undergraduate Research Poster Session, Wichita, KS;

October 27, 2010.


Glucosinolates.” American Chemical Society Midwest Regional Meeting, Undergraduate Research

Poster Session, Wichita, KS; October 27, 2010.

159. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” American Chemical

Society Midwest Regional Meeting, Undergraduate Research Poster Session, Wichita, KS; October

27, 2010.

160. Mays, J. R. “Synthetic Organic Isothiocyanates: Novel Chemoprotective Agents?” BCAAP Seminar,

South Dakota State University, Brookings, SD; October 20, 2010.

161. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” American

Chemical Society Sioux Valley Section Poster Competition, The University of South Dakota,

Vermillion, SD; October 16, 2010.


Glucosinolates.” American Chemical Society Sioux Valley Section Poster Competition, The

University of South Dakota, Vermillion, SD; October 16, 2010.

163. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” American Chemical

Society Sioux Valley Section Poster Competition, The University of South Dakota, Vermillion, SD;

October 16, 2010.

164. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” Chemistry and

Physics Departmental Seminar Series, Augustana College, Sioux Falls, SD; October 1, 2010.

165. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” Gilbert

Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 22, 2010.


Glucosinolates.” Gilbert Science Center Fall Poster Presentation, Augustana College, Sioux Falls, SD;

September 22, 2010.

167. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Gilbert Science

Center Fall Poster Presentation, Augustana College, Sioux Falls, SD; September 22, 2010.

168. Lensing, C. J.; Mays, J. R. “Synthesis and Evaluation of Novel Isothiocyanates.” Sanford Program for

Undergraduate Research Poster Symposium, Sanford Research, Sioux Falls, SD; August 4, 2010.


Glucosinolates.” South Dakota Biomedical Research Infrastructure Network Convocation, The


170. Clark, J. J.; Mays, J. R. “Synthesis of Heterocyclic Glucosinolates and Sulforaphane.” South Dakota

Biomedical Research Infrastructure Network Convocation, The University of South Dakota,

Vermillion, SD; July 26, 2010.

171. Mays, J. R. “Chemical biology approaches to expand the utility of organic isothiocyanates as cancer

chemoprotective agents.” Chemistry and Physics Departmental Seminar Series, Augustana College,

Sioux Falls, SD; October 2, 2009.

172. Mays, J. R. “Chemical biology approaches to expand the utility of organic isothiocyanates as cancer

chemoprotective agents.” Cancer Biology Research Center, Sanford School of Medicine, Sioux Falls,

SD; August 17, 2009.

The University of Kansas – Lawrence, KS

173. Mays, J. R.; Hill, S. A.; Moyers, J. T.; Blagg, B. S. J. “Synthesis and evaluation of flavones and

isoflavone chimeras of novobiocin and derrubone.” National Institutes of Health Poster Session, The

University of Kansas, Lawrence, KS; October 24, 2008.

The University of Wisconsin – Madison, WI

174. Mays, J. R.; Weller, R.L.; Sarfaraz, S.; Muhktar, H.; Rajski, S.R. “Development of new myrosinase-

dependent histone deacetylase inhibitors as chemoprotectants.” 2005 Midwest Enzyme Chemistry

Conference, Chicago, IL; October 2005.

Gustavus Adolphus College – St. Peter, MN

175. Mays, J. R.; Hofmeister, G.E. “Synthesis and resolution of chiral trisphenols: An approach in

stereochemical control in Lewis-acid catalyzed reactions.” 225th American Chemical Society National

Meeting, New Orleans, LA; March 2003.

GRANT ACTIVITY

1. “Non-Natural Isothiocyanates as Anticancer Agents.” South Dakota BRIN Faculty Fellowship Program,

Role: Principle Investigator, June 1, 2015, Requested $99,994. Fully funded.

2. Participation in “South Dakota Biomedical Research Infrastructure Network (BRIN).” National

Institutes of Health Sponsored IDeA Award, Role: Research Mentor, 2015, Requested $14,400,000.

Fully funded (P20, GM103443), ~$15,000 in support allocated to J. R. Mays per year of participation.

Intended participation through summer 2020.

3. Participation in “South Dakota Experimental Program to Stimulate Competitive Research (SD

EPSCoR).” National Science Foundation RII Track 1 Award (IIA-1355423) and the state of South

Dakota, Role: Research Mentor, 2014, Requested $20,000,000. Fully funded. ~$10,000 in support

allocated to J. R. Mays per year of participation.

4. “Preparation of lead chemopreventive isothiocyanates and glucosinolates.” Augustana Research/Artist

Fund, Role: Principle Investigator, February 2014, Requested $6,580. Fully funded.

5. “Molecular Modeling and Simulation Using SYBYL-X at Augustana College.” 2014 Pittsburgh

Conference Memorial National College Grants Program, Role: Principle Investigator, September 2013,

Requested $10,000. Not funded.

6. “Synthesis and Kinetic Evaluation of Non-Natural Glucosinolates.” Augustana Research/Artist Fund,

Role: Principle Investigator, February 2013, Requested $7,000. Fully funded.

7. “Non-natural Isothiocyanates and their Evaluation against Human Breast Cancers.” National Institutes

of Health Academic Research Enhancement Award, Role: Principle Investigator, October 2012,

Requested $368,683. Not funded (impact score = 56).

8. “REU Site in Cellular and Molecular Biology at Sanford Research and Augustana College.” NSF REU

1262744, National Science Foundation, Role: Senior Personnel (Research Mentor), September 2012,

Requested $350,491. Fully funded.

9. “Preparation and Multifaceted Evaluation of Novel Non-Natural Isothiocyanates as Anticancer Agents.”

Sanford Research Cancer COBRE Pilot Grant (8P20GM103548), Role: Principle Investigator,

Requested $10,104, June 2012. Fully funded.

10. “Synthesis and Kinetic Evaluation of Non-Natural Glucosinolates: Understanding the Structural Basis

for Myrosinase-Catalyzed Generation of Isothiocyanates.” Research Corporation for Science

Advancement Single Investigator Cottrell College Science Award, Role: Principle Investigator,

Requested $45,000, November 2011. Not funded.

11. “Thioredoxin-1 Regulation of Isothiocyanate Chemoprotection.” PhRMA Foundation, Role:

Collaborator, September 2011. Not funded.

12. “Non-Natural Isothiocyanates and Novel Mechanisms of Isothiocyanate Generation: Studies Toward the

Development of Improved Anticarcinogenic Agents.” National Institutes of Health Academic Research

Enhancement Award, Role: Principle Investigator, September 2009, Requested $311,280. Not funded.

13. Participation in “South Dakota Biomedical Research Infrastructure Network (BRIN).” National

Institutes of Health Sponsored IDeA Award, Role: Research Mentor, 2008, Requested $16,600,000.

Fully funded (2 P20, RR016479), $90,000 in startup funds allocated to J. R. Mays for 2009 – 2011,

~$18,000 per year in salary, student stipends, and materials. Began participation in summer 2010.

Intended participation through summer 2013.

14. “Redesigning DNA Gyrase Inhibitor Cyclothialidine to be a Selective Inhibitor of Hsp90.” National

Institutes of Health Ruth L. Kirchstein National Research Service Award Individual Fellowship, Role:

Principle Investigator, December 2007, Requested $100,000. Not funded.

15. “Redesigning DNA Gyrase Inhibitor Cyclothialidine to be a Selective Inhibitor of Hsp90.”Department

of Defense Congressionally Directed Medical Research Programs Prostate Cancer Research Program,

Prostate Cancer Training Award, Role: Principle Investigator, June 2008, Requested $114,998. Not

funded.

16. “Redesigning DNA Gyrase Inhibitor Cyclothialidine to be a Selective Inhibitor of Hsp90.” American

Cancer Society Postdoctoral Fellowship, Role: Principle Investigator, October 2007, Requested

$138,000. Not funded.

17. Participation in “The Development and Evaluation of Purine and Coumarin Based Hsp90 Inhibitors.”

National Institutes of Health and the National Cancer Institute, Role: Postdoctoral Associate, 2005,

Requested $1,829,000. Fully funded (2 U01 CA120458), $45,000 per year for salary and benefits from

2007 – 2009.

18. “New Tools for Histone Deacetylase Inhibition.” National Science Foundation Graduate Research

Fellowship Program, Role: Principle Investigator, November 2004, Requested $40,500. Not funded.

19. “Development of New GI-Specific Histone Deacetyase Inhibitors as Chemoprotectants.” National

Institutes of Health, Role: Graduate Student, November 2004, Requested $100,000. Fully funded (R03

CA117519).

20. “Chemistry Biology Interface Training Grant.” National Institutes of Health and the National Institute of

General Medical Sciences, Role: Trainee, 1993, Requested $4,594,000. Fully funded (5 T32

GM008505-18), ~$30,000 per year allocated to J. R. Mays for salary and benefits from 2004 – 2007.

QUALIFICATION SUMMARY

Knowledge of the properties of organic and biochemical materials

Knowledge of the air- and water-sensitive synthetic theory and methodology used to prepare organic and

biochemical compounds

Knowledge of the techniques used to purify organic and biochemical compounds, including:

chromatography (flash [SiO2], MPLC, HPLC), electrophoresis, and crystallization

Comprehensive understanding of the instrumentation and experiments used to characterize organic and

biochemical compounds, including: NMR, FT-IR, MS, HRMS, and UV-Vis

Areas of teaching competence include general, organic, biochemistry, medicinal, and some analytical

chemistry

TECHNIQUES AND INSTRUMENTATION

Instrumental Methods NMR (1H, 13C, 19F, kinetic NMR, dynamic NMR), IR, MS, GCMS, UV/Vis,

HPLC, Molecular Modeling (Chimera, SYBYL-X)

Separation & Purification PTLC, column chromatography (SiO2), recrystallization, gel electrophoresis

(SDS-PAGE)

Organic Chemistry multi-step chemical synthesis, anhydrous synthetic methodology (vacuum

manifold, glove box), natural product semi-synthesis, construction of

chemical libraries

Molecular Biology protein isolation, western blot analysis, cell culture, antiproliferation assays

(manual, high-throughput)

Software Microsoft Office (Excel, Word, PowerPoint), Cambridgesoft ChemDraw,

Adobe Photoshop, Adobe Illustrator, Adobe Dreamweaver, Thompson

EndNote, Xlfit, SigmaPlot, GraphPad Prism, PC, Linux, Windows (Windows

95 – Windows 7)

RESEARCH INTERESTS

Chemical syntheses of bioactive organic compounds

Synthesis and application of prodrug mechanisms for drug delivery

Development of small molecules with anticancer activity (both chemotherapeutic and chemopreventive)

Analysis of Michaelis–Menten enzyme kinetic processes

Target-oriented construction of chemical libraries

Combinatorial chemistry and convergent syntheses

Identification of 2D- and 3D-quantitative structure–activity relationships (QSAR)

Computational modeling for drug/receptor complexes

Development of in vitro biochemical assays to screen chemical libraries

ACADEMIC SERVICE


2018 – Current Peer Reviewer, Bioorganic Chemistry

2017 – Current Curriculum Council

2016 – Current Peer Reviewer, Journal of Food Science and Technology

2015 – 2016 Mentor, New Faculty Mentoring Program

2015 – Current Peer Reviewer, Computational Biology and Chemistry

2015 – Current Peer Reviewer, The Journal of Natural Products

2015 Chair, Chemistry Laboratory Instructor Search Committee

2014 – 2016 Teacher Education Committee

2014 – Current Peer Reviewer, SciTechnol: Applied Bioinformatics & Computational Biology

2013 Food, Faculty, and Film, “Monty Python and the Holy Grail”; November 5, 2013

2013 – 2016 Coordinator, Chemistry/Physics Department Seminar Series

2013 Examiner, Graduate Thesis for Van Quan Vo, La Trobe University, Victoria, Australia

2013 – Current Textbook Reviewer, John Wiley & Sons

2013 Barry M. Goldwater Foundation Subcommittee: All-Goldwater Scholar Event

2013 – Current Textbook Reviewer, Cengage Learning TextReviews

2013 – 2014 Program Steering Committee for the Froiland/Gilbert Science Center Project

2013 General Education Proposal Subcommittee: The Natural Sciences

2013 Fast Five Presentation, “Musings on the Liberal Arts by a Medicinal Chemist”; March

20, 2013

2012 – 2016 Civitas Committee

2012 – Current Biochemistry Major Steering Committee

2012 – 2016 Faculty Advisor to the Augustana University Chapter of the Student Affiliates of the

American Chemical Society

2012 – Current Peer Reviewer, Mini Reviews in Medicinal Chemistry

2012 – Current Barry M. Goldwater Scholarship National Selection Committee

2012 – Current Peer Reviewer, The Journal of Medicinal Chemistry

2012 Chair of Moral Values Activity, “Life and Death”; March 29, 2012

2012 Chapel Sermon, “Shades of Grey?”; January 11, 2012

2011 – Current Distinguished Scholars Competition Interview Team

2011 Approval of W-Component for Chemistry 330: Biochemistry and Medicinal Chemistry

2010 – 2011 Faculty Advisor to the Augustana College Chapter of the Student Affiliates of the


2010 – 2012 Mikkelsen Library Committee (Chair, 2011 – 2012)

2010 Faculty Enlightenment, Augustana Faculty Meeting ; October 6, 2010

2009 – Current Y.T. Johnson Science Day Committee

2009 – Current Y. T. Johnson Science Day, Break-Out Session Leader

2009 – Current Biochemistry Major Co-Coordinator

2009 Biochemistry Major Task Force


2004 – 2006 Pharmaceutical Sciences Graduate Liaison Committee

PROFESSIONAL AFFILLIATIONS


2010 – Current The American Chemical Society, Division of Medicinal Chemistry


2004 – 2006 The American Chemical Society

HONORS AND AWARDS


2018 1st Place, American Chemical Society Sioux Valley Section 2018 Poster Competition,

POET Research, Sioux Falls, SD

2017 2nd Place, American Chemical Society Sioux Valley Section 2017 Poster Competition,

Augustana University, Sioux Falls, SD

2017 3rd Place, American Chemical Society Sioux Valley Section 2017 Poster Competition,

Augustana University, Sioux Falls, SD

2017 2nd Place, Undergraduate Research Symposium Poster Competition, Pierre, SD

2016 Honorable Mention Student Chapter Awarded to the Augustana College Student

Affiliates of the American Chemical Society

2015 Commendable Student Chapter Awarded to the Augustana College Student Affiliates of

the American Chemical Society

2014 Green Chemistry Award for the Augustana College Chapter for the Student Affiliates of





Graduate Education and Applied Research Center, Sioux Falls, SD







2012 Outstanding Poster, Midwest Regional Meeting of the American Chemical Society,

Omaha, NE





2011 Outstanding Student Chapter Awarded to the Augustana College Student Affiliates of the


2011 Best Poster (Biochemistry subcategory), Midwest/Great Lakes Joint Meeting of the

American Chemical Society, St. Louis, MO


2004 – 2007 NIH Chemistry-Biology Interface (CBI) Training Grant

2003 – 2004 Wisconsin Alumni Research Foundation (WARF) Fellowship

Gustavus Adolphus College – St. Peter, MN

2003 Valedictorian (Unweighted cumulative GPA = 4.00)

2003 Hollingsworth Key Award

2002 – 2003 Chemistry Department Academic Assistant Award

2002 Barry M. Goldwater Scholar in Mathematics, Science and Engineering

2001 Gerhard Alexis Scholarship

2001 American Chemical Society Polymer Chemistry Award

2000 Freshman Chemistry Award

1999 – 2003 Partners in Scholarship Award

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