• Builtonexperience Pharmaceutical publisher Samedan Ltd is a well-established, highly regarded voice of the industry

• Globalcoverage Every issue, 10,500 copies of the magazine are distributed to our specially targeted readership across the world

International Clinical Trials (ICT) is a specialist journal designed to provide global coverage of key topics pertinent to the clinical trials sector.

Published quarterly, and edited by Dr Graham Hughes, the journal offers a platform of communication and information-sharing for executive and strategic decision-makers, seeking out new trends and marketing opportunities, as well as putting a spotlight on the latest innovations coming to market. ICT is specifically designed to be of interest to those actively seeking to source services for improved efficiency in what is an increasingly competitive market.

It achieves this by publishing a comprehensive collection of articles written by prominent figures spanning the clinical trials arena. Authors are invited to write on a wide range of relevant and interesting topics charting developments in the clinical trial industry, including: clinical development; global outsourcing; and drug delivery; as well as specialist subject areas such as clinical trial supplies; patient recruitment and

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US33.9%

Geographical distributionJob titles

Readership & Circulation

Media Information

retention; and EDC. The journal also features a regular preview and review section, keeping readers up-to-date with the hottest industry meetings.

Distribution is targeted directly at strategic decision-makers within pharmaceutical companies and their contract partners, primarily in Europe, but increasingly to North America and the rest of the world. ICT is fast proving itself to be a powerful advertising platform for organisations wishing to target this highly competitive marketplace.

Heads of IT/Data Management

Corporate Heads

Compliance

Regulatory Affairs

Biostatictics and Analysis

Lab Analysis

Heads of Clinical Trial Manufacuturing

Belgium2.1%

France5% Germany

6%Italy2.4%

The Nethetlands2.5%

UK21.8%

Rest of Europe9.9%

Switzerland2.5%

Japan4%

India1.9% China

4%Canada4%

Heads of Operations

GCP Auditing

QA/QC

Clinical Trials

Clinical Research

Clinical Trial Management

R&D Project Management

Marketing

ICTispublishedquarterlyinFebruary,May,AugustandNovember.

Digital edition2007 marked the launch of the new digital version of the magazine – you can register to view for free the page-turning online edition at www.samedanltd.com, where it’s also possible to download low res PDFs and print off articles. This has further enhanced distribution and provides an exciting new feature that complements the printed editions.

• EditorialintegrityICT is committed to commissioning the hottest topics written by eminent commentators from the drug development scene

Editorial Calendar

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Editorial integrityInternational Clinical Trials is committed to providing its readers with objective articles that tackle the themes of the day. Every article goes through the editing process in order to maintain our impartiality.

ICT is always keen to hear from you with ideas for features. Let us know if you want to provide an article (typically 1,500 and 2,500 words) – simply email a synopsis (100-200 words) of your proposed subject to the editorial team. Please note that due to various constraints, editorial topics on the calendar may alter and articles commissioned for one issue may be postponed until a later issue.

Past contributorsDrStuartJMair, Medical Advisor, Charles River LaboratoriesDrGunterBellaire, Director of Operations, Perceptive InformaticsMichaelMcGrath, Global VP of IT, ICONMarcBuyse, Founder, International Drug Development Institute

Winter 2008(February)

Spring 2009(May)

Summer 2009(August)

Autumn 2009(November)

TRIAL MANAGEMENT

Staff recruitment tacticsPharmacokineticsLate phase challenges

•••

Micro dosingUse of biomarkersPatient retention strategiesAcademic trials

••••

Medical imagingEarly phase trialsTrials of drug/device combinations

•••

Clinical trials administratorsADMEPatient recruitmentTranslation/semantics

••••

eCLINICALPatient diariesAdaptive trial designData security

•••

LIMSIVRSData sharing between companies

•••

Adaptive trials CDISC developments

••

eDiaries & pensCDISC LIMS

•••

LOGISTICS & TRIAL SUPPLY

Safety testingData warehousingBiometricsCentral lab services

••••

Supply managementStorage facilities

••

Cool chain complianceCentral labs

••

Temperature packagingSupply chain efficiency

••

THERAPEUTICSOncology OsteoporosisECG, cardiac safety

•••

Cognition testing and imagingRespiratoryHigh risk compounds

•

••

DiabetesCNSAnti infective resistanceRheumatoid arthritis

••••

Urological disordersHIV/Aids

••

OUTSOURCING &

LEGAL

Latin AmericaCentral/SE AsiaEMEA’s SME office

•••

ChinaPartnerships with regulatorsClinical Trial Directive update

•••

Latin AmericaC&E EuropeEU & US legal update

•••

Clinical trial agreements, EUParallel trading

••

CONFERENCES DIA, Europe• DIA, US• Clinical Trials Congress• Partnerships in Clinical Trials•

NB Please note that publication dates and editorial topics are subject to change

Editorial Guidelines

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Articles included in International Clinical Trials vary between 1,500 and 2,500 words in length, and are usually accompanied by whatever visual materials (photographs, diagrams, graphs and so on) the author is able to provide.

The absolute prerequisite of unpaid articles in ICT is that they are non-promotional contributions. We are looking for objective discussion of the author’s particular subject as opposed to information regarding their company’s activities or services. We are happy for the author to write on any aspects they consider pertinent or of particular interest, and we

by-line the author and the company concerned. All articles go through our thorough editing process to ensure accuracy and consistency, so your article may differ from the original text sent.

So that we have an idea of the direction you intend to take, we ask for a short synopsis (100-200 words) of your proposed subject. This helps to avoid disappointment should the same topic be tackled by more than one contributor. Please note that due to various constraints, it sometimes happens that articles commissioned for one issue have to be postponed until a later issue.

What to send• Text in an unformatted Word document should be emailed as an attachment.• A contact email address for the author(s) is also required that can be printed at the end of the article.• Please include a short biography (100-150 words) about the career and education of the author(s). • We prefer to include pictures of any author(s) with each biography. This, along with any images or diagrams,

can be emailed as jpeg, tiff or eps files of at least 300 dpi at the size they are to be used.• A note on references – please supply references in the following format:

1. Name AB, Name BC, Name CD and Name DE, Paper Title, Journal xx: pp xxx-xxx, 20072. Name EF, Name FG, Name GH and Name HI, Paper Title, Journal xx: pp xxx-xxx, 2007Their position in the text should be marked by: (1), (2) etc. Please try to keep references to a minimum – we can only publish more than 20 references per article in exceptional circumstances.

What happens nextBefore publishing your article, we send by email a low res PDF of the final design proof to check and give written approval for. This takes place in the week before the issue goes to print and it is important that you or a colleague is available during this time to approve the article. In the interests of accuracy, we never run an article without final written approval of the design proof.

Four-pagereprint

Quantity: 1,000 2,000 3,000

Cost: £845 £878.50 £944.50

Six-pagereprint

Quantity: 1,000 2,000 3000

Cost: £950 £1250 £1480.80

ReprintsReprints allow clients a great opportunity to extend their marketing reach. Reproducing editorial features designed by our in-house team is the perfect tool for trade shows or mailouts, making it a cost-effective way to add another dimension to a marketing campaign.

Advertising Rates

Printed options

Website facilities for advertisers • Hyperlink from magazine website to client website• Banner logo on magazine website (see page 4 for

banner specifications)• Press release facility for the duration of advertising• Corporate profile of up to 350 words with logo

Digital publication opportunities • Basic advert optimisation (link to company website)• Rich media - Video – MPEG, AVI, WMV, MOV - Audio – MP3 - Flash Ad – SWF with fonts embedded - Note that the file size should not exceed 40MB.• Extra ad page facing the front cover – PDF, SWF

Double page spread £4,550

Single page £2,850

Half page (horizontal or vertical) £1,575

Third page (vertical only) £1,150

Quarter page £795

Front cover logo £1,500

Opposite content pages£3,750

(fullpageonly)

Opposite editor’s letter£3,750

(fullpageonly)

Cover 2 (inside front cover)£4,950

(£7,750dps)

Cover 3 (inside back cover) £3,450

Cover 4 (outside back cover) £5,750

Additionalchargesfordigitaloptimisationvarydependingonthetypeofpackage.Pleasecontactsalesforfurtherinformation

Technical Guidelines

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Clientdesignedadvertsshouldbesuppliedinoneofthefollowingways• Adobe Acrobat PDF – advert PDFs must be supplied optimised for high quality printing. All colours (including pictures) must be CMYK, not RGB or

Pantone. They must include high resolution graphics (300dpi) and embedded fonts. Bleed adverts must include registration markings and bleed. We are unable to make amendments to PDF files.

• Adobe Illustrator CS2 – images and graphics must be embedded. Fonts should be supplied if they are not embedded/converted to outline.• QuarkXpress 6 (not Quark Passport) – with relevant high resolution graphics and fonts also supplied.

Howtosupplyfiles• Electronic files can be emailed to us• Larger files (above 10mb) should be supplied to us on CD or uploaded to our FTP site (ftp.samedan.com – contact us for login details)

Type Area(recommended margins)

Trim(page size)

Bleed(3mm minimum)

Doublepagespread 273 x 396 mm 297 x 420 mm 303 x 426 mm

Fullpage 273 x 186 mm 297 x 210 mm 303 x 213 mm

Halfpagehorizontal 135 x 186 mm 148 x 210 mm 151 x 213 mm

Halfpagevertical 273 x 92 mm 297 x 105 mm 303 x 108 mm

Thirdpage(verticalonly) 273 x 55 mm N/A N/A

Quarterpage 135 x 92 mm N/A N/A

NoteAll print adverts should be supplied with a colour copy of the advert. PDFs are supplied entirely at the client’s own risk and the publisher accepts no responsibility for any errors in printing. Powerpoint, CorelDraw and Microsoft Word files are not acceptable.

Web packagesSamedan web packages include banner advertising, company profiles and company logos. We are also able to list industry events in our dedicated online section.

WebsiteBannerSpecifications• Dimensions: 468x60 pixels or 200x150 pixels depending on page position• Resolution: 72 ppi• Format: *.gif /*.jpg/*.swf• Flash (*.swf ) video banners also accepted: must be 200 pixels in width, file size of no more than 120kb

CompanyProfileGuidelines• Profiles should be between 200 and 500 words and can include company contact details.• They can be accompanied by a logo, but we cannot make use of other images. Logos must be in *.jpg format and approximately 200x50 pixels.• Online banners are live on the site for 3 months. • Company profiles can be updated at any time if we are sent the relevant information.• Event listings are live for the duration of the lead-up to the event, and will be deleted once the event has taken place.

Contact the teamEditorialJohn White, john@samedanltd.com

AdvertisingDavid Hirsh, david@samedanltd.com

GeneralEnquiries

Samedan Ltd 16 Hampden Gurney StreetLondonW1H 5AL

Tel: +44 (0)20 7724 3456Fax: +44 (0)20 7724 2632 Email: info@samedanltd.comWeb: www.samedanltd.com