journal reading presentation gina
TRANSCRIPT
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JOURNAL READING
PREVALENCE AND RISK FACTORS FOR OCULAR
SURFACE DISEASE AMONG PATIENTS TREATED OVER
THE LONG TERM FOR GLAUCOMA OR OCULAR
HYPERTENSION
Regina Fristasari030.07.212
PEMBIMBING :Dr. Muhammad Edrial !.M
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M"st !atients "# !rimar$ "!en%angle glau&"ma 'P()G*re&ei+e l"ng%term medi&al treatment, "#ten #"r se+eralde&ades and s"me #"r the greater !art "# their li#etimes,
sin&e e+en surgi&al !atients "#ten re-uire adun&ti+emedi&al thera!$.
/hese medi&ati"ns, hi&h are "#ten used #"r de&ades in&lini&al !ra&ti&e, ma$ al"ne &ause &hr"ni& inammati"n
and"r ma$ ea&er4ate !reeisting "&ular sur#a&e disease,su&h as dr$ e$e, Mei4"mian gland d$s#un&ti"n, "r &hr"ni&allerg$.
IN/R(D56/I(N
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/he g"als "# the stud$ ere
1* t" estimate the !re+alen&e "# "&ular sur#a&e disease,stratied 4$ se+erit$, in !atients treated #"r P()G(8/
and2* t" identi#$ ris9 #a&t"rs #"r de+el"!ment "# "&ular sur#a&e
disease in glau&"ma !atients thr"ugh statisti&alanal$sis.
PURPOSE
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/his stud$ as designed as an "4ser+ati"nal, &r"ss%se&ti"nal
stud$ t" des&ri4e "&ular sur#a&e disease in !atients
treated #"r P()G(8/, ith a 1%m"nth in&lusi"n !eri"d.
Patients ere re&ruited 4$ a gr"u! "# 0 "!hthalm"l"gists
s!e&iali;ing in P()G(8/ management, h" ere
instru&ted t" &"lle&t data #r"m 10 &"nse&uti+e !atients
meeting the in&lusi"n &riteria, ith"ut an$ attem!t t" sele&t
&ases, es!e&iall$ !atients !arti&ularl$ m"ti+ated 4$ "&ular
sur#a&e &"m!laints.
Data ere &"lle&ted thr"ugh an"n$m"us -uesti"nnaires
+ia a standardi;ed Internet%4ased &ase re!"rting #"rm.
MATERIAL AND METHODS
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this stud$ as t" -uantitati+el$ estimate
the !r"!"rti"n "# !atients in 3 gr"u!s
Gr"u! B: s&"re = >%10
Gr"u! 6: s&"re = 10%30
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) t"tal "# ?1 !atients ere in&luded in this stud$. /he &hara&teristi&s
"# these !atients are re!"rted in /a4le I: >?.@A
ere #emale 71.1A ere "+er 0 $ears "# age and >1.3A
"+er 70 $ears.
/he diCeren&es ere e!lained 4$ the use "# ed &"m4inati"ns
in hi&h 2 drugs ere deli+ered thr"ugh 1 '1
!atients* "r 2 dr"!s '31 !atients*.
(ur s&"ring meth"d dened 3 gr"u!s '), B, and 6*,
a multin"mial l"gisti& regressi"n as &"ndu&ted.
/his led t" 2 "dds rati"s '(R* #"r ea&h &lass &"nsidered. F"r eam!le,
the (R "# 4eing aged 0%70 $ears as &"m!ared t" 4eing
aged less than 0 as 1.7 '@?A 6I 1.00%3.17* #"r gr"u!
B and 1.7 '@?A 6I 0.%3.1* #"r gr"u! 6.
RESULT
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FIGURE 1
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DISCUSSION
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)s e!e&ted, "lder !atients, th"se ith l"nger treatment
durati"n, and th"se ith m"re se+ere glau&"ma ere m"re
li9el$ t" !resent ith m"re se+ere "&ular sur#a&e in+"l+ement.
Indeed, age, durati"n "# treatment, and se+erit$ "#
disease ma$ 4e related, sin&e "lder !atients are m"re li9el$
t" ha+e had the disease l"nger, t" ha+e underg"ne m"re
treatment, and t" ha+e m"re se+ere glau&"ma.
M"re"+er, >0A "# the stud$ !"!ulati"n had re!"rted a hist"r$
"# treatment m"di&ati"n related t" "&ular sur#a&e issues
CONCLUSION
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Patients treated #"r !rimar$ "!en%angle glau&"ma "r "&ularh$!ertensi"n "#ten ha+e
"&ular sur#a&e diseases, m"re "#ten and m"re se+erel$ in
"lder !atients re&ei+ing m"re drugs and!resenting ith m"re se+ere glau&"ma. /hese high!re+alen&e +alues might there#"re ha+e &"nse-uen&es
"n the 4urden "# the disease in terms "# adheren&e t"treatment and -ualit$ "# li#e.
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THANK YOU