june 4, 2019 state legislation to increase vaccination ... · 6/4/2019 · olive jk, hotez pj,...
TRANSCRIPT
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Tammy R. Beckham, DVM, PhDActing Director, National Vaccine Program Office
June 4, 2019
State Legislation to Increase Vaccination CoveragePanel Introduction
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Saad B. Omer, MBBS MPH PhDWilliam H. Foege Professor of Global Health
Professor of Epidemiology and Pediatrics
Vaccine Mandates: An Overview of Evidence
@SaadOmer3
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Conflicts?
None
4
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5
Reasons For Non-Vaccination Among Measles Cases2000-2015
Other156 (31%)
Nonmedical exemptions…
43% of all cases
Phadke et al. JAMA, 2016
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0
20
40
60
80
100
1 2 3 4 5 6 7 8 9
Percen
t of
measl
es c
ase
s
Time in weeks
Vaccination status of measles cases by week
Unvaccinated
Unknown vaccination
status
Vaccinated
6
Cumulative Epidemic Curve of 16 Measles Outbreaks 2000 - 2015, United States
Phadke et al. JAMA, 2016
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Measles-susceptible Children in the United States
7
Bednarczyk, Orenstein, Omer. Am. J. Epi, 2016
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Measles Incidence & Vaccine Coverage For Top Countries for Immigration and Outbound Travel
8
Bednarczyk RA, Orenstein W, Omer SB. J Travel Med., 2016.
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9
Brewer et al., Psychol Sci Public Interest. 2017
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10
School Immunization Requirements
State laws (not
federal)
3 types of exemptions allowed
1. Medical2. Religious
3. Personal belief(philosophical)
Major role in low rates of vaccine
preventable diseases
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Ease of Obtaining Vaccine Exemptions –by State
Omer et al., New England Journal of Medicine . 2012Figure (with updated 2013 data) created by Mother Jones
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Ease of Obtaining Vaccine Exemptions in the U.S. - by State
Exemption Policies & Whooping Cough Incidence, 1986-2004
Omer et al., JAMA, 2006
Exemption ease
Incidence Rate Ratio
Difficult Reference
Medium 1.35 (0.96-1.91)
Easy 1.53 (1.10-2.14)
Omer et al., New England Journal of Medicine . 2012Figure (with updated 2013 data) created by Mother Jones
13
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14
Non-Medical Exemptions by Year 1991 - 2003
0.0%
0.5%
1.0%
1.5%
1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003
Exe
mpt
ion
Rat
e
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15
Nonmedical Exemptions for States With Religious Exemptions and With Personal Belief Exemptions
1991 - 2004
Data updated
Only Religious Exemptions Permitted Personal Belief Exemptions Permitted
Omer et al., Journal of American Medical Association, 2006
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Nonmedical Exemptions by Ease of Exemption 1991 - 2007
16
Easy Exemption Policy
Medium Exemption Policy
Difficult Exemption Policy
Data updatedOmer et al., JAMA, 2006
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Mean (95% CI) Rates of Nonmedical Exemptions by Type of Exemption, 2006–2011
Omer et al., NEJM, 2012
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Omer et al., New Eng Journal of Medicine, 2012 18
Mean (95% CI) Rates of Nonmedical Exemptions by Ease of Exemption,
2006–2011
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Relative Locations of Pertussis Space-time Clusters & Exemptions Spatial Clusters
Unadjusted OR
3.0 (2.5 – 3.6)
Adjusted OR
2.7 (2.2 – 3.3)
Overlap of
Exemptions
Clusters with
Pertussis Clusters
Omer et al., Am. J. Epi., 2008
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Washington Exemption Law
• SB 5005• Educational counseling and signed form from a licensed (in WA) health care
provider in order to obtain a nonmedical exemption
20
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
Law in effect July 22, 2011
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Impact of Change in Washington Exemption Law
0%
2%
4%
6%
8%
10%
1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014
An
y Ex
em
pti
on
Rat
e
Year
Overall (Before)
Overall (After)
Regression Line (Before)
Regression Line (After)
21Omer et al., Pediatrics, 2017
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Omer et al., New Eng Journal of Medicine, 2009 22
WA State Counties’ School Entry Exemption Rates -2006-2007
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24
Delamater et al., 2019, Pediatrics
Elimination of Nonmedical Immunization Exemptions in California & School-Entry Vaccine Status
(home schoolers etc.)
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Association of State Non-medical Exemption Policies With Medical Exemption Rates
25
Stadlin, Bednarczyk, Omer JID 2012
0
50
100
150
200
250
300
350
400
Difficult Medium EasyMe
dic
al E
xem
pti
on
s /1
00
,00
0
Non Medical Exemption Category
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26
Clusters of high not-up-to-date rates in California
Not Up-To-Date Rates
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Effects of potential legislative and administrative actions on vaccine up-to-date rates
Delamater et al., Unpublished
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Omer, New York Times (Op-Ed), Feb 2015
In-person counseling
Procedures to review each request for exemption
Sign a form that discusses the risks of non-vaccination
Letter elaborating on the reason their child should be exempt
Obtain the form by specifically requesting from the state or local health department, vs. downloading it online
Annual renewal
28
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Acknowledgments
29
@SaadOmer3
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Vaccines, Autism, and
Vaccine Exemptions
Peter Hotez, M.D., Ph.D.
Texas Children’s Hospital Endowed
Chair in Tropical Pediatrics
Dean, National School of Tropical Medicine
at Baylor College of Medicine
Former US Science Envoy
@PeterHotez
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Vaccine Scientist, Pediatrician, Autism Dad
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Vaccine TargetingHookworm and Schistosomiasis Co-Infections
A MULTIVALENTVACCINE TARGETING HOOKWORM + SCHISTO
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U.S. Science Envoy
Program
Leishmaniasis: “Aleppo Evil”
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Texas Children’s Hospital Center for Vaccine
Development
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TEXAS NON-MEDICAL VACCINE EXEMPTIONS (2003-2019)
2,314 2,722 6,9919,60610,404
12,633
19,05022,910
28,43232,616
38,19740,997
44,716
52,75656,738
64,176
2003to
2004
2004to
2005
2005to
2006
2006to
2007
2007to
2008
2008to
2009
2009to
2010
2010to
2011
2011to
2012
2012to
2013
2013to
2014
2014to
2015
2015to
2016
2016to
2017
2017to
2018
2018to
2019
35
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Texas Tribune
Schools with Highest Rates of Vaccination Exemptions
School Percent exemptedAustin Waldorf School (Travis) 40.51%Regents Academy (Nacogdoches) 37.75%Austin Discovery School (Travis) 30.06%Joshua Adv Multi-Gr Sch (Johnson) 26.67%Trinity Christian Academy Paris (Lamar) 23.86%The Khabele School (Travis) 22.08%Aesa Prep Academy (Travis) 20.65%
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Fig 1. Increasing nationwide trend in kindergarten NME rates from 2009 to 2017.
Olive JK, Hotez PJ, Damania A, Nolan MS (2018) Correction: The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties. PLOS Medicine 15(7): e1002616. https://doi.org/10.1371/journal.pmed.1002616https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002616
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Heat map of county-level NME rates in 2016 to 2017
Olive JK, Hotez PJ, Damania A, Nolan MS (2018) Correction: The state of the antivaccine movement in the United States: A
focused examination of nonmedical exemptions in states and counties. PLOS Medicine 15(7): e1002616.
https://doi.org/10.1371/journal.pmed.1002616
http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002616
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Heat map of counties with >400 kindergarteners with NMEs in 2016 to 2017
Olive JK, Hotez PJ, Damania A, Nolan MS (2018) Correction: The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties. PLOS Medicine 15(7): e1002616. https://doi.org/10.1371/journal.pmed.1002616 http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002616
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Fig 4. Negative relationship between state percentage of kindergarten MMR vaccine uptake and
NME rate in the 2016 to 2017 school year.
Olive JK, Hotez PJ, Damania A, Nolan MS (2018) The state of the antivaccine movement in the United States: A focused examination of nonmedical exemptions in states and counties. PLOS Medicine 15(6): e1002578. https://doi.org/10.1371/journal.pmed.1002578https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002578
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Sarkar et al (2019) Lancet Infect Dis
Measles resurgence in the USA: how international travel compounds vaccine resistance
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MISSISSIPPI IMMUNIZATION REQUIREMENTS
BECKY SHIPP, RN, BSN
MISSISSIPPI STATE DEPARTMENT OF HEALTH
IMMUNIZATION PROGRAM DIRECTOR
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OVERVIEW
.
• Mississippi Legislation• Immunization Compliance
• Immunization Requirements• School
• Licensed Child Care Facilities
• Regulation• Immunization Compliance
• Medical Exemptions
• Vaccination Coverage Rates• School Entry
• 19-35 Months
• 13-17 Years
• Successful Partnerships
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Mississippi Code 41-23-37
State Health Officer
• Specifies immunizationpractices to control vaccinepreventable diseases (VPDs)
Schools Defined - All Enrolled Children
• Public, Private, or Kindergarten
• Similar Type of Facility(intended for instruction ofchildren)
• Exception – legitimate homeinstruction program (defined bylaw) 47
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Mississippi Code 41-23-37
Certificate of Vaccination
• Issued on forms specified bythe MS State Board of Health
Exemption - Medical Reasons
• Application by duly licensedphysician on behalf of a child
Schools Report to the MSDH
• Immunization compliancestatus of enrolled children,October & December eachyear 48
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Mississippi Immunization Requirements
Diptheria, Tetanus, Pertussis (DTaP)
Inactivated Polio (IPV)
Hepatitis B (Hep B)
Measles, Mumps, Rubella (MMR)
Varicella (VAR)
Tdap (7th Grade Entry)
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School Entry (K4 – 12th)
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Mississippi Immunization Requirements
Diptheria, Tetanus, Pertussis (DTaP)
Inactivated Polio (IPV)
Hepatitis B (Hep B)
Measles, Mumps, Rubella (MMR)
Varicella (VAR)
Haemophilus influenzae type b (Hib)
Pneumococcal (PCV)
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Licensed Child Care Facilities
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MISSISSIPPI CERTIFICATE
OF IMMUNIZATION
COMPLIANCE FORM 121
51
Required for Attendance
Schools (K4-12th grade)
& Licensed Child Care Facilities
(Physical Copies On-site)
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Mississippi Certificate of Immunization Compliance –Form 121
MS Immunization Registry
Form 121 - Prepopulated Fields
Accessible to medical professionals
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Mississippi Certificate of Immunization Compliance –Form 121
Validation of Compliance
• Requires signature of medicalprofessional
• MD, DO, PA, NP, RPh, RN, LPN
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MS Immunization Registry
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MISSISSIPPI MEDICAL
EXEMPTION REQUEST
FORM 139
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Mississippi Medical Exemption Request –Form 139
• Submissions Accepted From• Child’s pediatrician, family physician,
or internist licensed in MS.
• Child’s out-of-state tertiary carephysician (reviewed on a case-by-casebasis).
• Exemption Status – EachVaccine• Permanent
• Temporary (requires expiration date)
• No Exemption
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Mississippi Medical Exemption Request –Form 139
• Documentation Required ofRequesting Physician• Reason for Medical Exemption
• Physician Contact Information
• Declarative Statement
• To validate physician’s decision for vaccineexemption request
• To ensure appropriate education has beenprovided to the parent/guardian
• Includes MS Medical License Number & NPI #
• Submissions to MSDH Central Office• Reviewed by State Epidemiologist or
Deputy State Epidemiologist for:
• Completion of Documentation Requirements
• Not Validated56
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MISSISSIPPI CERTIFICATE OF
MEDICAL EXEMPTION
FORM 122
• Completed & Signed By• State Epidemiologist or Deputy
State Epidemiologist
• Copies Sent To• Requesting Physician
• Parent
• Accepted By• Schools
• Licensed Child Care Facilities
• Originals Filed at MSDH• During threat of VPD occurring in
the community, child will beexcluded from school/facility perMSDH guidance
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Mississippi NIS-Child Vaccination Coverage Rates 2010 - 2017
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Source: Centers for Disease Control & Prevention Child Vax View at https://www.cdc.gov/vaccines/imz-managers/coverage/childvaxview/data-reports/index.html
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Mississippi NIS-Teen Vaccination Coverage Rates 2010 -2017
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Source: Centers for Disease Control & Prevention Teen Vax View at https://www.cdc.gov/vaccines/imz-managers/coverage/teenvaxview/data-reports/index.html
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SUCCESSFUL PARTNERSHIPS
• Vaccine Access & ComplianceValidation• Statewide Medical Professionals
• Compliance Assurance• MS Department of Education
• MSDH Licensure Division
• Advocacy• MS Chapter AAP
• MS Public Health Association
Protecting
Mississippians from
Vaccine Preventable Diseases
IMMUNIZATION REQUIREMENTS
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THANK YOUBecky Shipp, RN, BSN
(601) 576-7751
www.healthyms.com
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Richard Pan, MD, MPH, FAAPCalifornia State Senator
Author of AB2109, SB277 & SB276
sd06.senate.ca.gov
: RichardPanMD : @DrPanMD
#VaccinesWork #SB277 #CommunityImmunity #FakeMEsHurtKids #SB276
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Los A
ng
eles Times
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do
Efforts to Enhance Vaccine Coverage: Colorado 2019
National Vaccine Advisory Committee
June 4-5, 2019
John M. Douglas, Jr., MD
Executive Director
Tri-County Health Department
Adams, Arapahoe, & Douglas Counties, Colora
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Historical Perspective
• 1978: First school-required immunization laws in CO
• Included medical, personal, religious exemptions
• 2007: CO Immunization Information System
• 2014: HB 14-1288 requiring
• All schools and licensed childcare facilities to reportannual immunization and exemption rates
• Exemptions required to be filed every year for schools
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Colorado Immunization Trends: Kindergartener Up-to-Date Rate for All Vaccines and Personal Exemptions
Data Source: Colorado Department of Public Health and Environment, Immunization Branch
Data Caveats: 1. Variable publicity, legislative efforts
over time2. Changing vaccines, ACIP recs,
compliance definitions, surveymethods
3. Wide CIs all years
Expulsion threat removed
Data collection impaired due to FERPA matters (06/7 thru 10/11)
HB 1288 expanding IZ & exemption reporting:
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Colorado Up-to-Date and Exemption Rates for Schools Statewide: 2017-18
Data Source: Colorado Department of Public Health and Environment, Immunization Branch
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Colorado Up-to-Date Rates for Schools, Denver Metro and Tri-County Area, 2017-18
Data Source: Colorado Department of Public Health and Environment, Immunization Branch
Denver MetroTri-County Area
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MMR Coverage and Exemptions by Colorado County, 2017-18 School Year
MMR Exemptions MMR Coverage
Data Source: Colorado Department of Public Health and Environment, Immunization Branch
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MMR Vaccination Rates in Tri-County Jurisdiction 2017-18
Data Source: Colorado Department of Public Health and Environment, Immunization Branch, Adapted by Tri-County Health Department
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Colorado School District Immunization Fact Sheets (CCIC)
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Colorado School District Immunization Fact Sheets (CCIC)
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Growing Risk of Measles
Estimated Percentage of Kindergartners with Documented MMR Vaccine, 2017-18 MMWR
Oct 12, 2018
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Colorado HB 19-1312• CDPHE required to
• Develop standardized form and submission process to claimexemptions
• Develop & distribute educational materials
• Develop annual report on exemptions
• State board of health required to develop:
• Rules adopting the medical exemption recommendations fromACIP
• Rules adopting hepatitis A, rotavirus, and meningococcalimmunizations;
• Inclusion of HPV and influenza initially proposed and dropped
• Submission of exemptions
• Medical: MD, PA, NP completed form to be provided to school
• Personal, religious: parent/student completed forms to beprovided to state or local health dept
• Follow-up year filings can be completed on-line
• Immunizations and exemptions to be entered into CIIS
• Parent can opt of either
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Controversies over CO HB 19-1312
• Bill-specific
• Degree of difficulty of filing exemptions
• Use of ACIP language regarding medical exemptions
• Inclusion of new vaccines
• HAV, rotavirus, meningococcal included
• HPV, influenza dropped
• General concerns
• Vaccine side effects
• Use of aborted fetal tissue in vaccine production
• Confidentiality of CIIS
• Suspicion of “big pharma”
• Parental rights
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Stance of Governor on CO HB 19-1312
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Final Upshot: Not Enough Time
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Acknowledgements
• Stephanie Wasserman, CO Childrens Immunization Coalition
• Lynne Trefren, Colorado Dept Public Health and Environment
• Paul Gillenwater, CDPHE
• Ottavio Pirrochi, CDPHE
• Rep Kyle Mullica, CO Legislature