kcl med mock exam 0304

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    Kings College LondonGKT School of Medicine

    U N I V E R S I T Y O F L O N D O N

    This paper isnotpart of an examination of the college counting towards the award of a degree.

    Examinations are governed by the College Regulations under the authority of the Academic Board.

    MBBS5MOCK EXAMINATION

    GKTVIRTUAL CAMPUS

    EXAM INSTRUCTIONS FOR CANDIDATES(This is what you should expect to see in the end of year exams)

    Time Allowed = 3 Hours (This mock exam should take 2 hours to complete section A & B)

    There are two sections within this exam paper; instructions & test numbers are given at the beginning of

    each section. Please use a pencil to answer on the MCQ answer sheets.

    A normal values sheet has been provided.

    Candidate Number: last four digits of your official College candidate number

    (eg. E01234 = 1234).MCQ Test Number: (See beginning of each section)

    College Number: 10

    DO NOT REMOVE ANY PART OF THIS EXAM PAPER

    FROM THE EXAMINATION ROOM

    TURN OVER WHEN INSTRUCTED (Virtual Campus - when your ready!)

    2003 Kings College, London MG5MB5

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    MBBS Part 5 Mock Exam - 2 - continued on next page

    MB BS PART 5 EXAM

    SECTION A

    There are 75 questions in this section, which should be answered on the

    MCQ answer sheet that has SINGLE CORRECT RESPONSE written

    on the bottom left of the sheet.

    Please complete the following details on the MCQ answer sheet on your desk:

    Date: Day/Month/Yearof exam

    Name (please also write your desk number on this line)

    Last four digits of your candidate number

    Test number:College number: 10

    For each question you should mark ONE answer on the MCQ sheetprovided. Please do not make any other marks on the sheet.

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    MBBS Part 5 Mock Exam - 3 - continued on next page

    SECTION A SINGLE BEST RESPONSE

    1 An elderly man has severe headaches with a tender, red, inflamed temporal artery which has

    prevented him from sleeping for weeks. He is beginning to feel unwell. His Hb is 10g/dl

    and his ESR is 80mm/h. On the day he sees his GP he has blurring of the right eye. What is

    the most appropriate therapy?

    A Non steroidal anti-inflammatory agents

    B Intra-venous corticosteroids

    C Intra-venous penicillinD Intra-venous immunoglobulins

    E Methotrexate

    2 A 70 year old otherwise fit woman presents with a short history of a painless swelling in the

    left breast. Examination reveals a 2.5cm swelling, slightly irregular with overlying skin

    dimpling and tethering. No nodes are palpable in the left axilla. What is the most likely

    diagnosis?

    A Fibroadenoma

    B Duct ectasia

    C Fibroadenosis with cyst

    D Ductal carcinomaE Traumatic fat necrosis

    3 A large cohort study investigating the association of consumption of alcohol and stomach

    cancer shows that those who drink more than 21 units of alcohol per week have a relative

    risk of developing stomach cancer of 1.35 (95% confidence interval 1.10 to 1.75) compared

    to those drinking 21 units or less per week. On the basis of this finding, which of the

    following is true?

    A Alcohol intake above 21 units per week causes stomach cancer

    B The more people drink the more likely they are to get stomach cancer

    C Countries with a high average alcohol intakes have a higher prevalence of stomach

    cancerD People who drink more than 21 units of alcohol per week are on average 13 times

    more likely to develop stomach cancer than those who drink less

    E There is a statistically significant increased risk of stomach cancer in those who

    drink more than 21 units of alcohol per week

    4 Which finding favours the diagnosis of motor neurone disease?

    A Sensory loss

    B Absent tendon reflexes

    C Muscle fasciculation

    D Muscle hypertrophy

    E Optic atrophy

    5 You are a GP. A 14 year old girl comes to your surgery requesting emergency contraception

    (morning after pill). Which is the most appropriate course of action?

    A You should give her the medication only if you are convinced she is able to make a

    mature and responsible decision.

    B You should give her the medication without question since it is available from the

    GP on demand for any at-risk patient.

    C You should not prescribe in this situation since it is illegal to do so without the

    parents explicit consent.

    D Your actions should take into account the legal rights of the unborn child

    E You should warn her of her foolishness and make her an appointment with thefamily planning clinic

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    MBBS Part 5 Mock Exam - 4 - continued on next page

    6 A 25 year old man comes into Accident and Emergency with supraventricular tachycardia.

    Carotid massage does not stop the attack which has already lasted three hours. He is

    normally well and is on no medication and has no other illnesses. What medication is

    preferentially used (treatment of choice) to stop the attack?

    A Intravenous lignocaine

    B Intravenous digoxin

    C Intravenous amiodarone

    D Intravenous adenosineE Intravenous quinidine

    7 An elderly woman falls in the ward and fractures the head of the left humerus. The fracture

    is minimally

    displaced and impacted. What is the most appropriate management?

    A Collar and cuff

    B Excision of the head of the humerus

    C Pin and plate

    D Replacement by an artificial head of the humerus

    E Reduction and realignment under anaesthetic

    8 A 19 year old female college student presents with a weeks history of severe fatigue, fever,

    sore throat and swollen lymph nodes in the neck, axillae and groins. Physical examination

    reveals symmetrical tonsillar enlargement with redness and exudate, petechiae on the palate

    and an enlarged spleen. Investigations showed a haemoglobin of 12g/dl and a white blood

    count of 4.6 x 109/l with 56% segmented neutrophil forms, 20% lymphocytes, 26% atypical

    lymphocytes and 4% monocytes. The platelet count is normal. What is the likely diagnosis?

    A Acute lymphocytic leukaemia

    B Streptococcal pharyngitis

    C Infectious mononucleosis

    D Herpes simplex virus infection

    E Toxic shock syndrome

    9 A 48 year old male is found through health screening to have repeatedly elevated blood

    pressures of about 190/110mmHg. He has had several weeks of headaches, but denies any

    chest pain or breathlessness. On examination he has a loud aortic second sound and a S4

    (atrial) sound. His ECG shows abnormal voltage changes and ST segment depression in the

    left ventricular leads. His urine contains 2+ of protein. Optic fundi show grade II

    hypertensive retinopathy. What would be the most appropriate management?

    A Advise weight loss and see again in 2 months

    B Arrange an exercise stress test

    C Hospitalise and give urgent intravenous antihypertensive medication

    D Begin oral hypotensives and see in 3 months

    E Begin oral hypotensives and see in 2 weeks

    10 A 27 year old woman presents with several weeks of polyuria, increased thirst and weight

    loss. She denies urinary urgency or painful micturition. Her BP is 120/80mmHg.

    Examination reveals decreased skin turgor, fungal infection of both feet and vaginal

    candidiasis. What is the next appropriate diagnostic investigation?

    A Full blood count

    B Blood glucose

    C Liver function tests

    D Serum calciumE Culture of the fungus

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    MBBS Part 5 Mock Exam - 5 - continued on next page

    11 A patient has been commenced on a monoamine oxidase inhibitor drug for depression. He

    presents to Accident and Emergency with a severe headache and vomiting. His blood

    pressure is 200/110mmHg. He tells you that his dentist prescribed an opioid-containing

    analgesic for a toothache. Which one of the following is the most likely diagnosis?

    A Essential hypertension

    B Migraine

    C Psychological stress reaction

    D Drug interactionE Menieres disease

    12 An elderly man has pneumococcal pneumonia and his temperature, while first subsiding,

    returns and becomes swinging. His breathlessness and pleural pain intensify and he has a

    high white blood cell count. The signs change from those of consolidation to those of a

    pleural effusion. A chest x-ray confirms an effusion. What is the next appropriate test?

    A CT scan

    B Bronchoscopy

    C Diagnostic pleural tap

    D Pulmonary function studiesE Re-check the sputum for resistant organisms

    13 A young man in his thirties has a heavy meal with alcohol and shortly after vomits and has

    severe thoracic and epigastric pain. He becomes breathless and hypotensive. When seen in

    Accident and Emergency he is noted to have subcutaneous emphysema in the root of the

    neck on both sides and a left-sided pleural effusion. What intrathoracic catastrophe has

    occurred?

    A Ruptured lower oesophagus

    B Tension pneumothorax

    C Massive pulmonary infarctD Dissecting aneurysm

    E Cardiac infarction with rupture of free left ventricular wall

    14 A young man is involved in a fight with knives. The front of his chest is penetrated, 2 cm

    medial to the left nipple. He is brought to Accident and Emergency hypotensive, pale,

    shocked, with a blood pressure of 80/60 mmHg, and a pulse rate of 130 beats per minute. On

    sitting him up his venous pressure is markedly raised in spite of probable hypovolemia and

    rises further on inspiration. What should be done next?

    A Insertion of pulmonary catheter to measure wedge pressure

    B Rapid intra-arterial transfusion of blood

    C Pericardial drainage

    D Insertion of central venous pressure line

    E Measure cardiac enzymes to detect cardiac contusion

    15 A child with acute leukaemia is treated with corticosteroids. Which infection, if the child is

    unwittingly exposed to it, is a particular hazard?

    A Rubella

    B Chicken pox

    C Scarlet feverD Whooping cough

    E Streptococcal pharyngitis

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    MBBS Part 5 Mock Exam - 6 - continued on next page

    16 The National Service Framework for coronary heart disease is a:

    A Document prepared by the local health authority to improve management of heart

    attack patients

    B Document prepared by the Royal College of Physicians to give guidance to

    clinicians on the management of heart attack patients

    C Document prepared by the National Health Service Executive outlining what is

    expected of health authorities, primary care teams and trust in the prevention

    treatment and rehabilitation of heart diseaseD National audit of the management of coronary hear disease

    E Guidance from the General Medical Council on how to maintain skills in the

    management of heart disease

    17 A man of 60 has progressive, painless, dysphagia with weight loss and a feeling of food

    sticking in the chest. There are no physical signs. The following may all be helpful but

    which is probably the most crucial test?

    A Oesophageal manometry

    B Oesophageal pH studies

    C Oesophagoscopy and biopsy

    D Barium swallowE Chest x-ray

    18 An obese woman has had intermittent retrosternal chest pain on swallowing food over many

    years. A stricture is shown radiologically and is believed to be benign. What is the most

    likely reason for this benign oesophageal stricture?

    A Systemic sclerosis

    B Medications (e.g. non-steroidal anti-inflammatory agents)

    C Caustic induced (e.g. alkalis)

    D Radiation

    E Reflux oesophagitis

    19 Which of the following is NOT seen as a complication of carcinoma of the lung

    A Ptosis

    B Hypertrophic pulmonary osteoarthropathy

    C Hypocalcaemia

    D Hyponatraemia

    E Adrenal metastases

    20 Symptomatic severe carotid stenosis causes strokes, transient ischaemic episodes and retinal

    infarction. In such patients which screening test is advocated, initially, to determine those

    who might be candidates for carotid endarterectomy?

    A Magnetic resonance angiography

    B Doppler duplex ultrasound

    C Carotid angiography

    D Positron emission tomography

    E CT Scan

    21 An elderly man has persistent rest pain in both feet. The pain is worse when in bed and he

    gets relief by dangling his feet out of the bed. What do you suspect?

    A Chronic venous obstruction

    B Acute deep vein thrombosis

    C Severe arterial occlusive diseaseD Gout

    E Neuropathy

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    MBBS Part 5 Mock Exam - 8 - continued on next page

    27 A worried man of 50 years presents to his GP with the complaint that he has passed bright

    red stools intermittently for two months which streaks the stool, splashes the lavatory pan

    and marks the toilet paper. This comes on either after straining at stool, or alternatively after

    occasional bouts of diarrhoea. The bleeding is painless. What is probably the likeliest

    cause?

    A Haemorrhoids

    B Anal fissure

    C Carcinoma of the colonD Colonic polyps

    E Ulcerative colitis

    28 A sexually active youth of 16 years presents to the Accident and Emergency department with

    a 4 hour history of right testicular pain. He has vomited twice On examination he has

    marked testicular tenderness and urinalysis shows no abnormality. The correct management

    is:

    A Further investigation with ultrasound to exclude a teratoma

    B An abdominal x-ray because of the vomiting

    C Urgent surgical exploration of the scrotumD Admission and treatment with tetracycline for a probable sexually transmitted

    disease

    E Referral to the next urological outpatient clinic

    29 A 60 year old asymptomatic man presents with a microcytic anaemia and a haemoglobin

    level of 7g/dl. What is the most probable cause?

    A Diverticulitis

    B Cancer of the sigmoid colon

    C Sickle cell anaemia

    D Cancer of the pancreasE Cancer of the caecum

    30 An elderly woman falls and is unable to get up. On examination her right foot and leg are

    externally rotated and the affected limb shows shortening. What fracture has occurred?

    A Pelvic

    B Ankle

    C Shaft of the tibia

    D Neck of the femur

    E Shaft of the femur

    31 Which one of the following is a particular problem after a recent stroke?

    A Depression

    B Hypomania

    C Schizophrenia

    D Social phobia

    E Panic disorder

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    MBBS Part 5 Mock Exam - 9 - continued on next page

    32 The diagnosis of urinary tract infections in young women is best confirmed by:

    A Radiographic demonstration of the presence of ureterovesicular reflux

    B The presence of pyuria

    C Eliciting a medical history of recurrent fever and abdominal pain

    D Ultrasonic examination of the kidneys and bladder

    E Bacteriological culture of an adequately collected specimen of urine

    33 Which is the most suggestive feature of infective endocarditis?

    A Appearing and changing murmurs

    B Erythema marginatum

    C Juxta-articular nodes

    D Atrial fibrillation

    E Lymphadenopathy

    34 Bronchial breathing characteristically occurs with:

    A Basal emphysema

    B ConsolidationC Pleural effusion

    D Pneumothorax

    E A raised diaphragm

    35 A young adult presents with two days headache, fever, without any neck stiffness or focal

    signs. He has widespread purpura over the trunk and limbs. He is gravely ill. What

    investigation is most helpful?

    A Lumbar puncture

    B Blood culture

    C Complete blood countD Fibrin degradation products

    E Plasma cortisol levels

    36 A middle aged man presents with several months history of rib and spine pain. A skeletal

    survey shows osteolytic lesions in the bones especially the skull. He is anaemic,

    hypercalcaemic and in renal failure. An ESR is 100 mm/h and his serum alkaline

    phosphatase is normal. There is no bony uptake on an isotope scan. What is his condition?

    A Multiple myeloma

    B Pagets disease

    C Prostatic metastases

    D Primary hyperparathyroidism

    E Renal osteodystrophy

    37 A young woman goes on holiday to the Caribbean. While there she develops a red scaly rash

    on her nose and cheeks with arthralgia and fever. On her return to hospital she has chest pain

    due to pericarditis. Pancytopaenia and proteinuria are discovered. What is the likely

    diagnosis?

    A Acute leukaemia

    B Systemic lupus erythematosus

    C Sarcoidosis

    D Acute rheumatic fever

    E Lyme disease

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    MBBS Part 5 Mock Exam - 10 - continued on next page

    38 A man of 30 has been well apart from an operation for coarctation of the aorta in his teens.

    While watching the TV he felt severe occipital pain and lost conciousness for a few minutes.

    He recovered quickly but had pain down the spine into both legs. In Accident and

    Emergency he is distressed because of pain, but is alert. He has a mild fever and his BP is

    160/100mmHg. There is neck stiffness but no focal signs in the CNS. In the right fundus

    there is a canoe-shaped subhyaloid haemorrhage. What is the most likely diagnosis?

    A Massive intracerebral haemorrhageB Subarachnoid haemorrhage

    C Subdural haematoma

    D Fulminating meningitis

    E Hypertensive encephalopathy

    39 Q waves in inferior myocardial infarction appear in which ECG leads?

    A I and II

    B II, III and aVf

    C V1, 2 and 3

    D I, aVf and V6E V4, 5 and 6

    40 An elderly man has been immobile for 3 weeks after a stroke. For 1 week he has been

    restless and has increasing thin, watery, highly offensive stools leaking continually into the

    bed. His abdomen feels lumpy and an abdominal x-ray shows a ground glass homogeneous

    appearance in the pelvis. Spurious diarrhoea is suspected. What is the probable cause?

    A Rectal prolapse

    B Volvulus of the colon

    C Faecal impaction in the rectum

    D Pseudomembranous colitisE Intestinal hurry from a high osmolar diet

    41 A central venous line is being placed via the subclavian vein in an elderly man when he

    suddenly becomes breathless and his oxygen saturation fails. What complication is most

    likely to have happened?

    A The wire has threaded into the left ventricle

    B His chronic obstructive airways disease has been exacerbated

    C A pneumothorax has been created

    D A mycocardial infarction has been induced

    E Air embolism has occurred

    42 A man of 40 comes to Accident and Emergency complaining of a hot red, swollen, painful

    knee joint and inability to walk. This should first be assumed to be due to:

    A Crystal arthritis

    B Septic arthritis

    C Trauma

    D A coagulation disorder

    E Monoarticular rheumatoid arthritis

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    MBBS Part 5 Mock Exam - 12 - continued on next page

    48 A boy after a road traffic accident has a ruptured spleen which requires removal. What long

    term hazard is he liable to?

    A Venous thrombosis of the legs

    B Repeated pneumococcal infections

    C Cirrhosis with portal hypertension

    D Polycythaemia

    E Increased fragility of the skin following surgery

    49 A middle aged woman has upper abdominal pain, jaundice and rigors for several days. Her

    liver is tender and enlarged on palpation. A full blood count shows leukocytosis. What is

    the likely diagnosis?

    A Viral hepatitis

    B Acute cholecystitis

    C Acute cholangitis

    D Pancreatic cancer

    E Drug induced hepatitis

    50 A middle aged woman loses weight, her abdomen becomes swollen and distended with fluid

    and her umbilicus everted. Examination suggest a tumour and a diagnosis is made of

    peritoneal carcinomatosis. This is most likely to be due to:

    A Colonic cancer

    B Pancreatic cancer

    C Stomach cancer

    D Ovarian cancer

    E Hepatoma

    51 A middle aged man with a long history of indigestion and recent NSAID (non-steroidal anti-inflammatory drug) therapy is taken to the Accident and Emergency department because of

    sudden postural syncope and a feeling of faintness. He is noted to be pale, perspiring and

    hypotensive. His pulse is 120 per minute. Digital rectal examination reveals black tarry

    stools. What is the most likely underlying diagnosis?

    A Caecal carcinoma

    B Colonic diverticulitis

    C Angiodysplasia of the colon

    D Bleeding peptic ulcer

    E Jejunal ulceration

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    MBBS Part 5 Mock Exam - 13 - continued on next page

    52 You are married with three children, and your partner works as a GP, and you work as a

    surgical SpR.. Your partner has complained that you are coming home later and later, and

    going into work on your days off to see if you can help the team with patients. Your partner

    also tells you that you seem to be taking too much alcohol, although you only drink wine

    with your evening meal. Which of the following is a reasonable and healthy response to this

    difficult situation?

    A You tell your partner that you are a dedicated and mature doctor, who needs

    understanding, time but most of all space to dedicate to your workB You row with your partner, and explain that your work comes first.

    C You ignore your partner, and finish the bottle of wine before going to bed on your

    own, because you have an early start the next day.

    D You go into work to help the team who have trouble without you there

    E You talk to your GP and ask for professional advice and help, because you are not

    sure you understand what is happening.

    53 An asthmatic comes into hospital with a sudden acute episode of breathlessness and wheeze.

    She is not responding to nebulized salbutamol, inhaled steroids, intravenous aminophylline,

    oxygen, hydration and antibiotics. Arterial blood gases are being monitored as well as hervital signs in case she needs ventilating. What other measures are indicated for this young

    woman?

    A Intravenous corticosteroids

    B Sedation

    C Intravenous metronidazole

    D Sodium cromoglycate

    E Digoxin and diuretics

    54 A known drinker, previously well, in his 30s presents in shock, with acute abdominal pain,

    hyperglycaemia, hypocalcaemia, disseminated intravascular coagulation and renal failure.He later develops non-cardiogenic pulmonary oedema (ARDS). What is the likely

    diagnosis?

    A Acute pancreatitis

    B Peptic ulcer perforation

    C Cholecystitis

    D Leaking abdominal aorta

    E Mesenteric thrombosis

    55 A 17 year old girl presents with a foul smelling vaginal discharge. Speculum examination

    reveals a foamy green-yellow discharge in the posterior fornix. She admits to a longstanding

    relationship and is taking oral contraceptives. There are petechiae on the cervix. A wet

    mount shows motile organisms. Her partner is asymptomatic. What is the most likely

    organism involved?

    A Candida albicans

    B Gardnerella vaginalis. (Hemophilus vaginalis)

    C Chlamydia trachomatis

    D Trichomona vaginalis

    E Beta haemolytic streptococcus

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    56 A woman with advanced metastatic breast cancer is admitted with vomiting, thirst,

    constipation and drowsiness. A neurological examination and CT brain scan reveal no cause

    for her deterioration. She improves following rehydration with intravenous 0.9% sodium

    chloride. What metabolic condition is causing her problem?

    A Hyperphosphataemia

    B Hypercalcaemia

    C Hyponatraemia

    D UraemiaE Hypermagnesaemia

    57 A man of 50 years has crushing chest pain with sweating. He is taken to Accident and

    Emergency within 1 hour of the onset. Which ECG change would lead you to initiate

    thrombolytic therapy?

    A Right bundle branch block

    B ST segment elevation in left ventricular leads

    C Widespread ST segment depression

    D Q waves in septal leads

    E Prolongation of the QT interval

    58 A man of 60 years has refractory heart failure due to ischaemic myopathy in spite of digoxin

    and diuretic therapy. Echocardiography reveals no surgically amenable valve disorder but

    shows global dysfunction. Electrolyte levels and renal function are normal. What

    medication should be tried next?

    A ACE inhibitors

    B Verapamil

    C Disopyramide

    D Phosphodiesterase inhibitors

    E Propranolol

    59 In the prevention of infective endocarditis which one of the following conditions strongly

    warrants antibiotic prophylaxis in a patient about to visit a dentist for scaling?

    A Atrial septal defect

    B Ventricular septal defect

    C Previous coronary artery by-pass grafting involving the use of the internal mammary

    arteries

    D Presence of a dual chamber pacemaker

    E Previous pericarditis

    60 A man with chronic renal failure is anaemic and the picture is one of normocytic

    normochromic anaemia. What measures specifically improves the anaemia of chronic renal

    failure?

    A Corticosteroids

    B Folic acid

    C Vitamin B12

    D Iron

    E Erythropoietin

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    61 A man with a history of alcoholism is admitted to hospital for an emergency

    appendicectomy. On the third post-operative day he becomes confused, agitated and suffers

    visual and auditory hallucinations. His hands are too unsteady to feed himself. The next day

    he has a seizure. What is the most likely diagnosis?

    A Delirium tremens

    B Korsakoffs syndrome

    C Wernickes encephalopathy

    D Alcoholic hallucinosisE Alcoholic intoxication

    62 A patient prescribed a depot phenothiazine develops a mask-like face, tremor at rest, rigidity,

    akathisia and a shuffling gait. What medication if given concurrently prevents these

    extrapyramidal features?

    A Levodopa

    B Diazepam

    C Procyclidine

    D Carbamazepine

    E Clomipramine

    63 An elderly man, who does not drink alcohol, has mild chronic dementia. Abruptly his

    condition worsens. His memory, attention and awareness of his surroundings deteriorates.

    He no longer knows where he is, he hallucinates and becomes disturbed and distressed. He

    is aggressive, hyperactive and unmanageable at home. What medication is given for

    immediate action to calm him down while the doctors identify the reason for his

    deterioration?

    A Fluoxetine

    B Haloperidol

    C DiazepamD Lithium

    E Amylobarbital

    64 Which of the following death certificates will NOT be accepted by the Registrar for Births

    & Deaths

    A 1a. bronchopneumonia

    1b. carcinoma of the bronchus

    B 1a. left anterior myocardial infarction

    1b. coronary artery thrombosis

    2. diabetes mellitus

    C 1a. hyaline membrane disease

    1b. prematurity

    1c. abruption of the placenta

    D 1a. haemoperitoneum

    1b. traumatic rupture of the spleen

    2. malaria

    E 1a. heart failure

    1b. aortic stenosis

    1c. chronic rheumatic fever

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    65 A male diabetic aged 70 years normally controlled by a once daily long acting insulin is

    admitted to hospital with acute cellulitis, fever and a urine loaded with sugar and ketones.

    His blood sugar is 22 mmol/l. He is thirsty, incontinent, but is not vomiting and he can keep

    down food and drink. What hypoglycemic agent is most suitable during this illness?

    A An increase in long acting insulin

    B Soluble human insulin

    C Metformin

    D An oral sulphonylureaE A combination of metformin and a sulphonylurea

    66 A young man of 20 years complains of chest pain worse on breathing 3 weeks after an upper

    respiratory tract infection. He has no abnormal physical signs other than a fever and a

    scratchy sound in systole and diastole. His ECG shows widespread ST segment elevation in

    all leads except V1 and aVr with the concavity upwards. Serial ECGs show the ST

    segments return to the base line and then the T waves start to invert. What does the clinical

    picture suggest?

    A Unstable angina

    B Hyperventilation syndromeC Pulmonary emboli

    D Evolving cardiac infarction

    E Acute pericarditis

    67 A reduced ratio of forced expiratory volume in one second to forced vital capacity

    (FEV1sec/FVC) is a characteristic finding in spirometry in what condition?

    A Pleural effusion

    B Diaphragmatic paralysis

    C Chronic obstructive airway disease

    D Pulmonary fibrosisE Kyphoscoliosis

    68 Which of the following investigations is covered by IR(ME)R 2000 legislation

    A HIV screen

    B Routine ultrasound

    C CT head scan

    D MRI scan of lumbar spine

    E 24 hour ECG

    69 For a patient with Diabetics the optional blood pressure must be under:-

    A 130/90

    B 130/80

    C 140/80

    D 150/70

    E 145/85

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    70 A woman of 20 years with acute thyrotoxicosis is started on carbimazole. After 2 weeks she

    develops a persistent and worsening sore throat with fever and mouth ulceration. What is the

    first and most appropriate test that is required?

    A Throat swab

    B Paul Bunnell test

    C Blood culture

    D Serum immunoglobulins

    E White blood cell count

    71 The highest rate of suicide in the UK is seen with:

    A Young women and teenagers

    B Young men

    C White elderly men

    D Black elderly men

    E White elderly women

    72 Which of the following therapies does not require you to be a Registered Practitioner?A Accupunture

    B Occcupational Therapy

    C Physiotherapy

    D Chiropractology

    E Reflexology

    73 A 20 year old man sustained a minor head injury during a fight in the pub. He presents 24

    hours later with marked ataxia, tremor, nystagmus, dysmetria and dysarthria. The best

    course of action is to order

    A A CT scan of headB A lumbar puncture

    C A period of observation

    D An angiogram

    E An EEG

    74 A single girl of 16 has primary dysmenorrhoea with severe crampy, lower abdominal pain on

    the first two days of her period which prevents her attending school. What should be the first

    line of treatment?

    A Danazol

    B Mefenamic acid

    C Combined oral contraceptive pill

    D Dilatation and curettage

    E Gonadotrophin releasing hormone analogue

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    75 Your patient is undergoing surgery to remove a breast mass (lumpectomy) which is

    considered clinically to be benign. At operation you find that the mass is malignant and wish

    to proceed to a mastectomy. Medico-legally you are justified in taking the following action

    A You are ethically obliged to complete the mastectomy because this is in the patient's

    best interests

    B You should complete the mastectomy for humanitarian reasons to prevent

    unnecessary pain

    C You should obtain her partners consent to continue with the mastectomyD You should complete the lumpectomy only and after she has recovered from this

    procedure seek her written consent for a later mastectomy

    E Benign paternalism dictates you should immediately do what is best for the patient

    without distressing her further

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    MB BS PART 5 EXAM

    SECTION B

    There are 25 questions in this section, which should be answered on theMCQ answer sheet that has EXTENDED RESPONSE A written on the

    bottom left of the sheet.

    Please complete the following details on the MCQ answer sheet on your desk:

    Date: Day/Month/Yearof exam

    Name (please also write your desk number on this line)

    Last four digits of your candidate number

    Test number:College number: 10

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    SECTION B EXTENDED MATCHING

    1 Extended matching MCQ Public Health Theme: study design

    A cross-sectional study E controlled study

    B cohort study F migrant study

    C case control study G randomised controlled trial

    D ecological study H none of the above

    For each of the following situations select the most appropriate study design. Each option can be

    used once, more than once or not at all.

    1 (i) 1000 women with cervical cancer and 1000 age-matched women without cervical cancer

    are interviewed about their smoking history to study the connection between cervical cancer

    and smoking.

    2 (ii) Patients with gonorrhoea are given either multiple or single-dose antibiotic therapy to

    evaluate the effectiveness of single dose therapy in the treatment of gonorrhoea.

    3 (iii) One hundred patients with peripheral vascular disease treated by vein grafting (50 who

    continue to smoke and 50 who have stopped smoking) are followed for 5 years to compare

    the incidence of graft occlusion in the two groups.

    4 (iv) Rubber industry workers are surveyed regarding their health status and medical problems to

    determine the prevalence of occupational illnesses in various job groups.

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    2 Extended matching MCQ General Practice

    The following conditions may cause patients to behave abnormally in the community

    A alcohol withdrawal F hypothyroidism

    B Alzheimers disease G hypoxia

    C depression H schizophrenia

    D hypoglycaemia I steroid psychosis

    E hypomania J temporal lobe epilepsy

    As a general practitioner you are asked to visit the following patients. Select the one most likely

    working diagnosis:

    5 (i) The family of a 70 year old woman are concerned by a slow deterioration in her condition

    over the past few months. She has become paranoid and is accusing them of trying to

    poison her. She is very lethargic and, since you last saw her 6 months ago, has put on

    weight noticeably.

    6 (ii) A neighbour reports that Mr Thomas, a 75 year old patient of yours, has been found

    wandering in the streets. His wife died suddenly two months ago. When you visit him athome, he is clearly disorientated and doesn't recognise you.

    7 (iii) The daughter of a 79 year old woman, who was widowed 9 months ago, reports her mother

    is behaving oddly. She is very withdrawn and has become paranoid about the people in the

    flat opposite her whom she believes are spying on her. She has lost all motivation and

    rarely ventures out of the house.

    8 (iv) A patient of yours asks you to visit her 22 year old son who is home from university. He

    has become abusive and is accusing them of trying to steal his money. He is hyperactive

    and refuses to sleep, pacing the house all night. He is not on any medication.

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    3 Extended matching MCQ Medicine Theme: cough

    A acute bronchitis F primary lung carcinoma

    B asthma G pulmonary embolism

    C chronic obstructive pulmonary

    disease

    H sarcoidosis

    D cystic fibrosis I tuberculosis

    E pneumonia J viral pleurisy

    Select the diagnosis most appropriate for each clinical vignette. Each option may be used once,

    more than once or not at all.

    9 (i) A 59 year old man has had cough productive of blood-tinged sputum for eight hours. He

    has had temperatures to 38.9o C, malaise, shortness of breath, and a cough productive of

    yellow phlegm for two days. He has smoked two packs of cigarettes daily for forty years.

    Rhonchi, wheeze and crepitations are heard over the right hemi-thorax. An xray film of the

    chest shows a dense lobar infiltrate in the right hemithorax.

    10 (ii) A 25 year old man has had a cough productive of blood-streaked sputum for five days. Over

    the past six years he has had similar symptoms once or twice annually that have been

    successfully treated with antibiotic therapy. He has had a cough for twelve years, recently

    productive of one to two cups of yellow-green sputum daily. He does not smoke. He is an

    insulin-dependent diabetic and takes pancreatic extracts. Coarse rhonchi bilaterally and

    wheeze are heard. An xray film of the chest shows increased interstitial markings

    bilaterally, nodular lesions and hyper-inflation.

    11 (iii) A 47 year old woman has had a cough productive of scant amounts of yellow phlegm and

    temperatures to 38.3oC for three months. On one occasion the phlegm was blood-streaked.

    She has had a 10 kg weight loss over the past four months. She does not smoke. Sheimmigrated from Vietnam twenty years ago and medical records are unavailable. Coarse

    upper lobe crackles and rhonchi are heard bilaterally. An xray film of the chest shows

    multiple, bilateral, upper lobe cavities with surrounding infiltrates of the lungs.

    12 (iv) A 32 year old woman has suffered from an unproductive cough for three months, the onset

    of which she dates to a holiday in Tunisia. She notices her cough after climbing stairs to

    work. The cough is particularly troublesome at night and she has been self-medicating with

    cough linctus. Her only other medication is the oral contraceptive pill. She is not

    particularly troubled by breathlessness. On examination she is apyrexial and has no

    abnormal physical signs in her chest.

    13 (v) A 34 year old Afro-Caribbean gentleman has become progressively more breathless over the

    past two months. His symptom of breathlessness is complicated by an unproductive cough,

    most noticeable on exertion. He works as a mortuary attendant, smokes between 5-10

    cigarettes per day and drinks no alcohol. He received BCG at school. His only other

    complaints are of occasional recent irritation of the eyes and of right upper quadrant

    abdominal discomfort. The physical examination is unremarkable, spirometry reveals

    FEV1\FVC was 3.4\3.7 litres (predicted 3.8\4.6 litres), and liver function tests were mildly

    elevated.

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    4. Extended matching MCQ Surgery Theme: rectal bleeding

    A anal fissure F irritable bowel syndrome

    B angiodysplasia G ischaemic colitis

    C diverticular disease H rectal carcinoma

    D duodenal ulcer I ulcerative colitis

    E haemorrhoids

    Select the diagnosis most appropriate for each clinical vignette. Each option may be used once,

    more than once or not at all.

    14 (i) A 19 year old boy with a history of diarrhoea and weight loss over the past year. Three

    months previously he developed a perianal abscess. He has noticed blood mixed in with his

    stool and is opening his bowels 8 times a day.

    15 (ii) A 34 year old woman with pruritus ani but no pain on defecation, who has noticed spots of

    bright red blood on the toilet paper after opening her bowels.

    16 (iii) A 72 year old gentleman who has opened his bowels five times over the last 24 hours, each

    time passing several cupfuls of bright red blood. He is starting to feel light-headed, has a

    pulse of 96bpm, an Hb of 8g/dl, WCC of 10x109/l, platelets 325x109/l. He had a barium

    enema three weeks previously which was reported as normal.

    17 (iv) A 50 year old man who has suffered increasingly with tenesmus and constipation over

    the past year and has lost 1 stone in weight. He has noticed bright red blood coating

    the stool.

    5. Extended matching MCQ Surgery Theme: abdominal mass

    A abdominal aortic aneurysm F hepatomegaly

    B appendix mass G incisional hernia

    C bladder (retention of urine) H rectus sheath haematoma

    D caecal carcinoma I sigmoid carcinoma

    E empyema of gall bladder J splenomegaly

    Select the diagnosis most appropriate for each clinical vignette. Each option may be used once,

    more than once or not at all.

    18 (i) A 21 year old man who reports fever, anorexia, nausea and poorly localised abdominal pain

    one week ago. He now complains of right sided abdominal pain.

    19 (ii) An 88 year old man who is hypertensive, and a life-long smoker arrives in casualty after

    collapsing at home with a pulse of 100 and blood pressure of 60/30.

    20 (iii) A 63 year old obese woman who had a previous perforated duodenal ulcer now presents

    with a non-tender, central abdominal mass which disappears on lying flat

    21 (iv) A 25 year old rugby player who suddenly developed pain in his right iliac fossa, whichworsens on movement.

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    6. Extended matching MCQ ENT Theme: hearing loss

    A acute labyrinthitis F middle ear effusion

    B acute suppurative otitis media G otosclerosis

    C chronic suppurative otitis media-

    tubotympanic type

    H presbyacusis

    D cholesteatoma I tympanic membrane perforationE Meniere's syndrome J wax in the ear canal

    Select the diagnosis most appropriate for each clinical vignette. Each option may be used once,

    more than once or not at all.

    22 (i) A 65 year old man is seen in the ENT outpatients with a history of progressive hearing loss

    in the right ear associated with a scanty offensive ear discharge. Examination shows a crust

    in the attic region. The Rinne test is negative in the right ear but positive in the left ear. The

    pure tone audiogram shows bilateral high frequency hearing loss but in addition there is a

    right-sided conductive hearing loss.

    23 (ii) A 28 year old lady complains of deafness following an upper respiratory tract infection three

    months ago. Examination includes a pure tone audiogram, which shows a bilateral

    conductive hearing loss and flat tympanograms.

    24 (iii) A 32 year old woman has had three attacks of acute rotatory vertigo associated with a

    hearing loss and tinnitus. The hearing loss and tinnitus resolved between attacks. On

    examination in the ENT Clinic there is little to find.

    25 (iv) An 80 year old man complains of a progressive hearing loss for several years. Examination

    of the ears shows normal tympanic membranes on both sides. The pure tone audiogramshows a bilateral high frequency hearing loss.

    End of Exam Paper

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    NORMAL VALUES

    ESR 1-15 mm/hr

    CRP