kidney - pathbliss · anomalies of position: •kidneys may fail to ascend •ascent may be...
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KIDNEYAnatomy, Embryology & Anomalies
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Anatomy
• Site: Retroperitoneal on either side of vertebral column
• Extent:
• Superiorly: T12
• Inferiorly: L3
Right kidney is slightly inferior
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• Size:
• Length: 11cm
• Breadth: 6cm
• Depth: 3cm
• Weight:
• Men: 150g
• Women: 135g
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• Orientation:
• Superior pole: Thick and round
• Inferior pole: Thinner
• Lateral border: Convex
• Medial border: Convex at the poles, concave in between
• Anterior Surface: Convex
• Superomedial: Adrenal gland
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• Hilum: Renal Vein (Anterior)
Renal Artery
Renal Pelvis (Posterior)
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• Perirenal fascia: Bilaminated sheet
Envelops the kidney, suprarenal gland and perirenal fat
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Embryology
• Kidney arises from 2 sources:
• Secretory part: Excretory tubules (nephrons) from nephrogenic cord
• Collecting part: from the ureteric bud arising from the mesonephric duct
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3 Stages of evolution
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Formation of Collecting system
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Development of Nephron
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Continued…
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• Ascent of the kidney:
Due to differential growth of abdominal wall
• Rotation of kidney:
• Initially, hilum is anteriorly
• Gradually rotates medially
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Anomalies of Kidney
• Agenesis: One or both kidneys
• Hypo/Hyperplasia
• Duplication: Extra kidney one side
• Can be separate or fused
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Anomalies of shape:
• Horseshoe kidney
Due to fusion of upper or lower poles
May lie in front or behind the aorta
Inferior mesenteric artery prevents its ascent
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Anomalies of shape:
• Pancake kidney
The two kidneys form one mass
May lie in the midline or on one side
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Anomalies of shape:
• Lobulated kidney
Persistence of lobulation of fetal kidney
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Anomalies of position:
• Kidneys may fail to ascend
• Ascent may be incomplete (lower lumbar)
• Ascends too far (thoracic cavity)
• Both kidneys may lie on the same side of midline
• Both kidneys may be displaced to the opposite side
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• Abnormal rotation:
• Non-rotation- Hilum is directed forward
• Incomplete rotation: Hilum faces anteromedially
• Reverse rotation: Hilum faces anterolaterally
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• Congenital polycystic kidney:
• Due to failure of contact of metanephros with collecting tubules
• Leads to formation to cysts
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• Aberrant renal arteries:
• Arteries arising at abnormal levels
• Common in cases of non-ascent or incomplete ascent
• These can press upon the ureter leading to hydronephrosis
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• Multiple anomalies: Two or more anomalies may co-exist