lab 22 –female reproductive system ii introduction female ... repro_2.pdf · female reproductive...
TRANSCRIPT
![Page 1: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/1.jpg)
FemaleReproductiveSystemII
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
![Page 2: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/2.jpg)
Learning Objectives
1. Identify the layers in the wall of the uterine tube, know the functions ofthe component cells, and recognize the different tubal regions.
2. Recognize the layers of the uterine wall, the functional significance oftheir components, and their changes during the menstrual cycle.
3. Recognize histological feature of the cervix, ectocervix, and vagina.
4. Understand the structure of the mammary gland and how it changesduring puberty, pregnancy, and lactation.
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
![Page 3: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/3.jpg)
Keywords
basal layercervixectocervixendometrial glandsendometriumfibrous support tissuefunctional layer
lactiferous ductmammary glandmyoepithelial cellsmyometriumperimetriumuterusvagina
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
![Page 4: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/4.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide60:Oviduct,Ampulla
Slide59:Oviduct,Isthmus
Ovary
![Page 5: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/5.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide19:Oviduct,MassonTrichrome
serosa
mucosa
muscularis
![Page 6: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/6.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide19:Oviduct,MassonTrichrome
mucosasimplecolumnarepitheliumandthinlaminapropria
muscularis
serosa
![Page 7: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/7.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide19:Oviduct,MassonTrichrome
ciliatedcellsciliahelpsweep
fluidtowarduterus
secretorypegcellsnon‐ciliated;secrete
nutritivefilm
laminapropria
![Page 8: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/8.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide60:Oviduct,Ampulla
Slide59:Oviduct,Isthmus
Examineslides59and60oftheoviducttoidentifythefollowingstructure:
mucosa muscularis serosa
Howdothestructurescomparefromoneslidetotheother?
![Page 9: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/9.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide1:Uterus,Trichrome
endometrium
myometrium
perimetrium
![Page 10: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/10.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
endometriummucosawithsimplecolumnarepitheliumandthickunderlyinglaminapropria containingglands
endometrial(uterine)glands
myometrium
Slide1:Uterus,Trichrome
![Page 11: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/11.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide1:Uterus,Trichrome
perimetriumprimarilyserosa
myometriumendometrium
![Page 12: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/12.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
functionallayer
basallayer
LayersofEndometrium
myometrium
![Page 13: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/13.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
MenstrualCycle
1)MenstrualPhaseSlide81
2)ProliferativePhaseSlide80Slide83
3)SecretoryPhaseSlide82Slide84
![Page 14: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/14.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide80:Endometrium,H&E
myometrium
perimetrium
endometrium
![Page 15: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/15.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide80:Endometrium,H&E
myometrium
• fewglandsinendometrium• lotsofspacebetweenglands
endometrialglands
![Page 16: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/16.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
endometrium
myometrium
Slide82:Endometrium,H&E
![Page 17: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/17.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide82:Endometrium,H&E
• morenumerous,jaggedglands
• presenceofthin‐walled,blood‐filledlacunaeinstroma
vascularlacunae
endometrialglands
![Page 18: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/18.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii.Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
myometriumendometrium
Slide81:Endometrium,H&E
![Page 19: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/19.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii.Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide81:Endometrium,H&E
• bloodinstroma,notinlacunae
• thick,well‐developedfunctionallayer
bloodinstroma
![Page 20: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/20.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide133:Cervix,H&E
cutedgestratifiedsquamousepithelium
cervicalglands
transitionofepithelium
![Page 21: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/21.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide133:Cervix,H&E
endocervical gland
ectocervix
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Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide108:MammaryGland,H&E
secretoryacini(lobule)
lobuleconsistsofmultipleacinialldrainingtosame
terminalduct
fibrousinterlobularsupporttissue
adipose
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Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide108:MammaryGland,H&E
lactiferousduct
secretoryacini(lobules)
fibroussupporttissue
![Page 24: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/24.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Slide108:MammaryGland,H&E
plasmacells
myoepithelialcell insidebasementmembranesecretoryaciniandductsarebothcomposedoftwolayersofcells:theluminalepithelialcellsandthebasalmyoepithelialcells
![Page 25: Lab 22 –Female Reproductive System II Introduction Female ... Repro_2.pdf · Female Reproductive System II Lab 22 –Female Reproductive System II A560 –Fall 2015 I. Introduction](https://reader035.vdocument.in/reader035/viewer/2022062919/5ee16959ad6a402d666c4dfe/html5/thumbnails/25.jpg)
Lab22– FemaleReproductiveSystemIIA560– Fall2015
I. IntroductionII. LearningObjectivesIII. SlidesandMicrographs
A. GenitalTract1. Oviduct(Fallopiantube)2. Uterusa. Generalstructureb. Phasesi. Proliferativephaseii. Secretoryphaseiii. Onsetofmenstruation
c. Cervix3. Vagina
B. MammaryGlandIV. Summary
Common Confusion:Seminal vesicle vs. Ampulla (of Oviduct)
Seminal Vesicle
Seminal vesicle: secretory gland of male reproductivetract, producing majority of seminal fluid volume; consistsof single tube coiled upon itself; joins with vas deferens toform ejaculatory duct
Look for: (1) glandular with the appearance of multiplelumens as result of coiling of tube; (2) highly‐foldedmucosa, often having fine “honeycomb” appearance; (3)non‐ciliated pseudostratified columnar epithelium withlipid droplets in cytoplasm giving “foamy” appearance; (4)lipofuscin pigment is often seen in mucosa
Ampulla of oviduct (uterine tube, Fallopian tube, orsalpinx): tube leading from ovary to uterus; tube transmitsovum to uterus and is the usual site of fertilization, usuallyin the ampulla
Look for: (1) single lumen tube w/ mucosa surrounded bymuscularis and serosa continuous with broad ligament; (2)mucosal folds often appear “thicker” than in seminalvesicle due to more lamina propria in the folds; (3) ciliatedsimple columnar epithelium and non‐ciliated “peg cells”present in mucosa; (4) size of muscularis changes withregion of oviduct, generally thin in ampulla and thick inisthmusOviduct
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Time (Days) of Cycle Influencing Hormones Thickness of Endometrium Endometrial Glands Vasculature
Proliferativephase
Secretory phase
Menstrualphase
Lab22‐ Characteristicsofuterinewallthroughoutmenstrualcycle